LOCUS       NZ_CP045704            22286 bp    DNA     linear   CON 03-SEP-2024
DEFINITION  Streptomyces rutgersensis strain NBH77 chromosome, complete genome.
ACCESSION   NZ_CP045704
VERSION     NZ_CP045704.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces rutgersensis
  ORGANISM  Streptomyces rutgersensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces diastaticus group.
REFERENCE   1  (bases 1 to 6848830)
  AUTHORS   Benaud,N., Edwards,R.J., Amos,T.G., D'Agostino,P.M.,
            Gutierrez-Chavez,C., Montgomery,K., Nicetic,I. and Ferrari,B.C.
  TITLE     Antarctic desert soil bacteria exhibit high novel natural product
            potential, evaluated through long-read genome sequencing and
            comparative genomics
  JOURNAL   Environ Microbiol 23 (7), 3646-3664 (2021)
   PUBMED   33140504
REFERENCE   2  (bases 1 to 6848830)
  AUTHORS   Benaud,N., Edwards,R.J. and Ferrari,B.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2019) School of Biotechnology and Biomolecular
            Sciences, University of New South Wales, Botany St, Sydney, NSW
            2052, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-DEC-2018
            Assembly Method                   :: FALCON v. v 1.8.6
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014216335.1-RS_2024_09_03
            Annotation Date                   :: 09/03/2024 04:34:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,921
            CDSs (total)                      :: 5,831
            Genes (coding)                    :: 5,642
            CDSs (with protein)               :: 5,642
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 189
            CDSs (without protein)            :: 189
            Pseudo Genes (ambiguous residues) :: 0 of 189
            Pseudo Genes (frameshifted)       :: 102 of 189
            Pseudo Genes (incomplete)         :: 130 of 189
            Pseudo Genes (internal stop)      :: 14 of 189
            Pseudo Genes (multiple problems)  :: 50 of 189
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:08:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5108342
            Orig. end                         :: 5130628
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045704.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Belinda Ferrari, QAP Lab
            4002, Bioscience South E26, UNSW Sydney, Australia 2052 (Quarantine
            regulated isolate).
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22286
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="14"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22286
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22286
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12286](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12286)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(547..1257)
                     /locus_tag="F0345_RS21510"
                     /old_locus_tag="F0345_21535"
     CDS             complement(547..1257)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893466.1"
                     /locus_tag="F0345_RS21510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21535"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_185393441.1"
                     /transl_table=11
                     /translation="MYGLYALKPWYAARLAGVRGALARRRVSPDALTAAGIGAASAAGA
                     ALALLPAGWAGAPVAVLLAARLACANLDGALARDTGRSTRRGALLNETGDRAADLVVVA
                     AFWPLAPGWLVALAACAATLPSWVSLAGAATGAVRLNGGPVGKTERCLLAVVAAATGWY
                     APVLAVLAVGSAATAVLRGARLWRELGAADRDGRASGEGLRARPAPAPALSPAAPCPPG
                     APATSTTTTTGRTR"
     misc_feature    1626..1641
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.82"
                     /tool="antismash"
     gene            1883..2020
                     /locus_tag="F0345_RS21515"
     CDS             1883..2020
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008406190.1"
                     /locus_tag="F0345_RS21515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_164495069.1"
                     /transl_table=11
                     /translation="MSAETTSAARRSRRAHRATETDRRNAAAALQRALDRRDNGGATGH
                     "
     gene            2148..3188
                     /locus_tag="F0345_RS21520"
                     /old_locus_tag="F0345_21540"
     CDS             2148..3188
                     /EC_number="1.1.1.85"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575023.1"
                     /locus_tag="F0345_RS21520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21540"
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="WP_115068125.1"
                     /transl_table=11
                     /translation="MSRSINLAVIPGDGIGQEVVAQGLKVLNAVLPEDVKLETKEYDLG
                     ARRWHRTGETLPDAELEALKQHDAILLGAIGDPSVPSGVLERGLLLKLRFAFDHFVNLR
                     PSKLFPNTATPLAGRPEIDFVVVREGTEGPYTGNGGSLRTGTPAEVATEVSVNTAYGVE
                     RVVRDAFARAQARPRKKLTLVHKNNVLVFAGHLWKNTFDKVAAEYPDVATDYLHVDAAT
                     IFFVTQPERFDVIVTDNLFGDIITDLAAAVTGGIGLAASGNVNPTGEFPSMFEPVHGSA
                     PDIAGQGKADPTATILSVALLLRHLGYEAEAARIEEAVSADLAERDGTARSTDAVGDAL
                     AGRVAG"
     misc_feature    2183..2197
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     gene            3609..4697
                     /locus_tag="F0345_RS21525"
                     /old_locus_tag="F0345_21545"
     CDS             3609..4697
                     /EC_number="2.6.1.42"
                     /GO_function="GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_4 (90-343). E-value: 6.1e-28.
                     Score: 90.1. Matches aSDomain:
                     nrpspksdomains_F0345_RS21525_Aminotran_4.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951042.1"
                     /locus_tag="F0345_RS21525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21545"
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="WP_100455091.1"
                     /transl_table=11
                     /translation="MTTPTIELKPSAHPLPAAEREAILARPGFGRHFTDHMVTVKWTEG
                     RGWHDGQLVPYGPLSLDPATNVLHYAQEIFEGLKAYRRPDGSVATFRPDANARRFQASA
                     RRLAMPELPVETFIEACDLLVAQDKAWVPPHGGEESLYLRPFMIATEVGLGVRPADEYL
                     FVVIASPAGAYFPGGVKPVSIWLSENRVRAVPGGVGDAKTGGNYAASLLAQAEAAAEGC
                     DQVAYLDAVEHKWVEELGGMNLCFVYGDRLVTPALTGSLLAGVTRDTLLSLAADLGHQA
                     EEGRVSIDQWREDSRSGALTEVFACGTAAVITPVGRVKTATDEWTQGDGEPGEVTLRLR
                     EALLALQTGRAEDRHGWMHPLG"
     aSDomain        3879..4637
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F0345_RS21525_Aminotran_4.1"
                     /evalue="6.10E-28"
                     /label="F0345_RS21525_Aminotran_4.1"
                     /locus_tag="F0345_RS21525"
                     /protein_end="343"
                     /protein_start="90"
                     /score="90.1"
                     /tool="antismash"
                     /translation="FRPDANARRFQASARRLAMPELPVETFIEACDLLVAQDKAWVPPH
                     GGEESLYLRPFMIATEVGLGVRPADEYLFVVIASPAGAYFPGGVKPVSIWLSENRVRAV
                     PGGVGDAKTGGNYAASLLAQAEAAAEGCDQVAYLDAVEHKWVEELGGMNLCFVYGDRLV
                     TPALTGSLLAGVTRDTLLSLAADLGHQAEEGRVSIDQWREDSRSGALTEVFACGTAAVI
                     TPVGRVKTATDEWTQGDGEPGEVTLRLREAL"
     gene            5064..5918
                     /locus_tag="F0345_RS21530"
                     /old_locus_tag="F0345_21550"
     CDS             5064..5918
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F0345_RS21530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F0345_21550"
                     /product="hypothetical protein"
                     /protein_id="WP_100455092.1"
                     /transl_table=11
                     /translation="MSHTEATGQWKEALEQTQGELKGLRGETRQGLRLQTEANADLRAI
                     REGVAELSAVVPLLRALAERDRATQPEAASGAGGTKAVHRADGRDAFAHGGNEQHPAAG
                     GISRGDDMADLDGGERPPHHDDLKAAIWAVYRGDGPQAAAPAAPHPCGPGRSGQAGLGP
                     EGEHGLLLLRAAGLASAELLAHRDTWEWFADLAVGHQHFRHPFQVEETKDGRVRTSLSG
                     RSLVAALIGLWERIEKAPVNTVDWAMATAYYQRVAGRLVNLTSQGGVIRIILDDGADDA
                     AED"
     misc_feature    complement(6325..6339)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.96"
                     /tool="antismash"
     gene            6614..8386
                     /gene="cimA"
                     /locus_tag="F0345_RS21535"
                     /old_locus_tag="F0345_21555"
     CDS             6614..8386
                     /EC_number="2.3.3.21"
                     /GO_function="GO:0043714 - (R)-citramalate synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046912 - acyltransferase activity, acyl
                     groups converted into alkyl on transfer [Evidence IEA]"
                     /GO_process="GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cimA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470910.1"
                     /locus_tag="F0345_RS21535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21555"
                     /product="citramalate synthase"
                     /protein_id="WP_229842524.1"
                     /sec_met_domain="HMGL-like (E-value: 2.1e-45, bitscore:
                     153.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQATPEEPADRAPSAATEPQVARDVRGGDGARPASAGTPVAVP
                     DTAAVDAAVARPLHIFDTTLRDGAQREGINLSVADKLTIARHLDDFGVGFIEGGWPGAN
                     PRDTEFFARAREEITFRNAQLVAFGATRRAGGSAADDLQVKALLDSGAPVVTLVAKAHD
                     RHVELALRTTLDENLAMVRDTVAYLRDQGRRVFVDCEHFFDGYAANPAYAKSVVRAASE
                     AGADVVVLCDTNGGMLPAQIQAVTATVLADTGARLGVHAQDDTGCAVANTLAAVDAGAT
                     HVQCTANGYGERVGNANLFPVVAALELKYGRTVLPEGALAEMTRISHAIAEVVNLTPST
                     HQPYVGVSAFAHKAGLHASAIKVDPDLYQHIDPELVGNRIRMLVSDMAGRASIELKGKE
                     LGIDLGEDRALVGRVVERVKERELAGYSYEAADASFELLLRDELRRGAHGGAEGEAPSR
                     FFRVESWRAITEDRPDGTHANEATVKLWAKGERILATAEGNGPVNALDRALRVALERIY
                     PQLAKFELRDYKVRILEGRSGTESTTRVLISTGDGDGEWSTVGVAENVIAASWHALEDA
                     YTYGLLRAGVAPVE"
     gene            8576..9934
                     /locus_tag="F0345_RS21540"
                     /old_locus_tag="F0345_21560"
     CDS             8576..9934
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642015.1"
                     /locus_tag="F0345_RS21540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21560"
                     /product="hypothetical protein"
                     /protein_id="WP_100455093.1"
                     /transl_table=11
                     /translation="MLGTAGATAVPAAAAPSAHSPAVAAAPERAPGRATVSEVATAWRE
                     GPVFVDPDVSDQLSDVQARDLSQEIQESDKAIFVAVLPATFTDDVDRTMNDLRGDTGIT
                     GLYVLRIGDDLHVRADRSVLSPQATQNLQSRFQGTTPAADQLSGLVGNATQNMGGRAPA
                     SWSAREGVPGSTWLGLGIAAVVVGGAAYTLTRRTKNRRAQAQREALDKLRVVVDEDITA
                     FGEELERLDFRPSEPGATDEMRGDYERALDAYENAKSLMDHAGKPEDVREVTKALEDGR
                     FALAVLDARRDGRELPVRRSPCFFDPRHGLSVADVTWAPAGGAPREVPVCAADQARLEQ
                     GEAPEIRTVESDGGGRRPYWEAGPAYGPWAGGYFGGGLLPGLLAGTMLGHMMMTPAYAA
                     DYGSAEGFGDGGAGGGYEGGDVSGSDFDPGDFGGGFGDGGGFGGGGGDFGGGF"
     gene            complement(10001..12286)
                     /locus_tag="F0345_RS21545"
                     /old_locus_tag="F0345_21565"
     CDS             complement(10001..12286)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414954.1"
                     /locus_tag="F0345_RS21545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21565"
                     /product="germacradienol/geosmin synthase"
                     /protein_id="WP_246332388.1"
                     /sec_met_domain="T1TS (E-value: 4.2e-81, bitscore: 271.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFVLPDFYVPYPARLNPHLEEARAHARVWADEMGMLEGSGVW
                     DLADLEAHDYALLCAYTHPDCDGPALSLVTDWYVWVFFFDDHFLELFKRTQDREGAKAY
                     LERLPAFMPMDLADGFPEPRNPVEAGLADLWARTVPAMSEDWRRRFALSTENLLNESMW
                     ELSNINAGRVSNPLEYIEMRRKVGGAPWSAGLIEYAAQAEVPEAVAYSRPLRVLTDAFS
                     DGVHLRNDLFSYQREVEEEGELSNGVLVLERFLECTTQEAAEAVNDLLTSRLQQFENTA
                     LTELGPLFADKGLNPAESASVLAYVKGLQDWQSGGHEWHMRSSRYMNEGAVDGGEAPPT
                     PGGSPGALAAALLGGTLGTSALDVRSFFGRPARQRARSFSHVPYQRTGASLLPDFKLPF
                     PTRLSPAMEQSRVDTVEWAHRMGLLVPQPGVPGSDVWDEEALAGYDFPLCAAGLHPEAD
                     LEELDLASQWLTWGTYGDDYYPAVFGRTRNFAGAKVCTDRLRDFMPVEQPSAGPVPTSA
                     LERSLADLWVRTASAMPEKARREFRKTIEVMLDSWVWELDNQAIGRIPDPIDYMEMRRA
                     TFGSDLTMSLCRLRHGNIVPEEVYRSGTVQAMEKAVSDYGALINDVFSYQKEVEFEGEI
                     HNAVLVTQNFFDCDYPTGLAYVDALMNARLEQFQHIVAHELPVLYEDFQLDAAARKVLD
                     GYVRQLENWLSAILTWHRGCVRYKEEDLSHHSPGVRRVIEAAPRGIGPNGLGPSTLGTA
                     AARVFAGG"
     gene            complement(12366..12632)
                     /locus_tag="F0345_RS21550"
                     /old_locus_tag="F0345_21570"
     CDS             complement(12366..12632)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893458.1"
                     /locus_tag="F0345_RS21550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21570"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_115068127.1"
                     /transl_table=11
                     /translation="MTGAPSLSQPLSWFKSSYSSDAGGNCIEVAYDWRKSSYSGSEGGN
                     CVEVAAHPTTVHVRDSKVPAGPVLDVAPAAWAAFVHATAGPLV"
     gene            complement(12629..13453)
                     /locus_tag="F0345_RS21555"
                     /old_locus_tag="F0345_21575"
     CDS             complement(12629..13453)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414952.1"
                     /locus_tag="F0345_RS21555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21575"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_185393442.1"
                     /transl_table=11
                     /translation="MQQRKKSSKKVTSWEVLGKQLAEFRRVAGLTQGQLADLARVGEDT
                     VSSVEQGRRRLQADLAERLDTILETKRALSTAVSTIPTHERYPLFAQDFIEHEQTAVTI
                     LSYESHVIPGLLQTSEYARTVFGNAYPPLTTQGLEEAVQARVDRKQILSRDIPPMMSFI
                     IEESVLLRHLGDPQAMSQQIQHLRDCADLPCLSLQVMPTNTDAHAGLAGPLVLLETPDH
                     DHLAYIEGHHRGFMVDDQDEVSAYQQKYGMLRAQALSPQKTKDLLNTLLGVK"
     gene            13566..13991
                     /locus_tag="F0345_RS21560"
                     /old_locus_tag="F0345_21580"
     CDS             13566..13991
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414951.1"
                     /locus_tag="F0345_RS21560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21580"
                     /product="ATP-binding protein"
                     /protein_id="WP_115068129.1"
                     /transl_table=11
                     /translation="METETRLPARCERFYRRERRSVPAARDFTAAVLDDWDARVPRDDV
                     LLCVSELATNALLHGVPPGRGFRLFVLRADDGGVRVEVHDSGDGHPATRAPGDEAESGR
                     GLLLVSALADDWGVGERDPGKSVWCSFRPLPVHHLGR"
     gene            14872..15402
                     /locus_tag="F0345_RS21565"
                     /old_locus_tag="F0345_21590"
     CDS             14872..15402
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960225.1"
                     /locus_tag="F0345_RS21565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21590"
                     /product="VOC family protein"
                     /protein_id="WP_100455098.1"
                     /transl_table=11
                     /translation="MSDYYDAFEISPVPAPGPDAVPPEPFRGIYGMPAFVNVPTTDLAA
                     SVEFWTRGLGFFELFVVPGTLVHLRRWAFQDVLLVAAPSVPEQPPAMSFSFSGVLDQVD
                     SLAAACRALRPDAVDGPRDTPWNTRDVEVVTPENARVVLTAAKPFDPAGQEARNLAAMG
                     ITPPGDGPGGRHG"
     misc_feature    15451..15465
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.98"
                     /tool="antismash"
     gene            15817..16599
                     /locus_tag="F0345_RS21570"
                     /old_locus_tag="F0345_21595"
     CDS             15817..16599
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414944.1"
                     /locus_tag="F0345_RS21570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21595"
                     /product="hypothetical protein"
                     /protein_id="WP_258057218.1"
                     /transl_table=11
                     /translation="MTRKTMWRTAVAGGAAVVFTGLTAVPAGAAEGGVSFTRVKVNSGK
                     PIVIGVKEEVEVPASGRMTTKLTFKGVPMVHPYRGKLGKGEELWSALGGGDPEGVDPVK
                     GVYDFAVAFSIHPRHAGLKNKDAGTWKTCARISLAGGGHDVDDENLPLQVKRATRLTVN
                     ASPEPVTKGKTLTVTGTVTRADWDKHTYQGYAGRTVSLQFRPAGASSYKTVKKARSNSK
                     GALKTTVKATGTGTWRWTYHGNSTSGARSSSGDHVAVK"
     gene            complement(16864..17538)
                     /locus_tag="F0345_RS21575"
                     /old_locus_tag="F0345_21600"
     CDS             complement(16864..17538)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414941.1"
                     /locus_tag="F0345_RS21575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21600"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_100455099.1"
                     /transl_table=11
                     /translation="MSDDGTRTAGDEARAEAVREAWARIDAWMRAHAPDSYEELAPPAG
                     PAAVEAAQAELGVRFPADLLASLACHDGLRHWANCLPVRPPLPVSEIVGHWRMCVEIDE
                     ANRADGEGREPEDEEPWWHPQWVPWAQSDGDAQIIDMRPGPDQGRLGMAYHDDCGVFEG
                     GWPSLSAYLTEVAEVLEKGGAVGGTWVPYLTCDGELWWSLKDETELNGEPLTPAPAPAA
                     AS"
     gene            complement(17988..18470)
                     /locus_tag="F0345_RS21580"
                     /old_locus_tag="F0345_21605"
     CDS             complement(17988..18470)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-154). E-value:
                     1.7e-20. Score: 65.8. Matches aSDomain:
                     nrpspksdomains_F0345_RS21580_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414939.1"
                     /locus_tag="F0345_RS21580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21605"
                     /product="SRPBCC family protein"
                     /protein_id="WP_100455100.1"
                     /transl_table=11
                     /translation="MRSTAEVSVAAVIEAEPKAVYERVADVASMGRWSPECVRTAAGVG
                     PAPVGAEFKGVNKGPSGRSWSTRCRVMVARPGERFTFRVRFWGMPVATWDYRFRPVGDG
                     TATEVTETAVDQRNRLLWFLGSAVSGVWDRSAHNAETMRRTLERLRETLEAERRTG"
     aSDomain        complement(18009..18458)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F0345_RS21580_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="1.70E-20"
                     /label="F0345_RS21580_Polyketide_cyc2.1"
                     /locus_tag="F0345_RS21580"
                     /protein_end="154"
                     /protein_start="4"
                     /score="65.8"
                     /tool="antismash"
                     /translation="AEVSVAAVIEAEPKAVYERVADVASMGRWSPECVRTAAGVGPAPV
                     GAEFKGVNKGPSGRSWSTRCRVMVARPGERFTFRVRFWGMPVATWDYRFRPVGDGTATE
                     VTETAVDQRNRLLWFLGSAVSGVWDRSAHNAETMRRTLERLRETLE"
     gene            18595..18972
                     /locus_tag="F0345_RS21585"
                     /old_locus_tag="F0345_21610"
     CDS             18595..18972
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151190.1"
                     /locus_tag="F0345_RS21585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21610"
                     /product="signal peptidase I"
                     /protein_id="WP_100455101.1"
                     /transl_table=11
                     /translation="MSENVYVGDAPTEAALDAGWIMGHFKAPDDPRHNEAVEIKWGVHE
                     AGDRRAAWVRGEERQALLVLVSGRFRMEFPGRDVVLSEQGQYVIWGKGVDHSWEAEEPS
                     VVMTVRWPSVPGYRVPETAAG"
     gene            complement(19698..20303)
                     /locus_tag="F0345_RS21590"
                     /old_locus_tag="F0345_21615"
     CDS             complement(19698..20303)
                     /GO_component="GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414932.1"
                     /locus_tag="F0345_RS21590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21615"
                     /product="YceI family protein"
                     /protein_id="WP_100455102.1"
                     /transl_table=11
                     /translation="MGIFGRKNETAATAATSAVNPDLAALTGTYTIDPAHTTIGFVARH
                     AMVTNVKGGFADFTGTLELDGADPANSSARIDVTMDSIDTGNADRDGHLKSADFFKTDE
                     FPQMTFRSTKAEALGGDDYRITGDLTILGTTRPLSIDLEFNGAAKDPFGNERVGFEGTA
                     SILRSEWGLTWNAALETGGVLVSDKIKLAFDISAIKNA"
     gene            20682..21221
                     /locus_tag="F0345_RS21595"
                     /old_locus_tag="F0345_21620"
     CDS             20682..21221
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470926.1"
                     /locus_tag="F0345_RS21595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_21620"
                     /product="hypothetical protein"
                     /protein_id="WP_100455103.1"
                     /transl_table=11
                     /translation="MKIRSALSALALVAGAGFGVIGTATAATAAPAPAGAAAEYGAAVT
                     KITHAQATSRFSSSGITWSSSGGCSNRNVSTCTSFDQLNLASAQGAQTLKSASGCALRI
                     TGGTETGHASGTYSHWNGYKLDFAKATCLNNYVTGHFTYIGQRGDGAAQYKSASGNIYA
                     NEGNHWDVTFHNCGGC"
     misc_feature    complement(21350..21366)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.48"
                     /tool="antismash"
ORIGIN
        1 cgcaccacgc gccgacatcc ccgaacgaca cggccacgcc caccgcgagc gccgccgggc
       61 ccagcaggac cagaccgcag agcgccaccg gtatccacag cagtccgagg agcgtgcgcc
      121 ccgcccgggt gaagcctcgt tccgcgtcgc cgtccagcag cgcgggcagt gccgccgcga
      181 ccagcagcag cgccaccgcc gggaggccca gccgctccgg cgcccgccag gccagcagtg
      241 gcagcagcac cgccgccccg gtcagcaccg ccccctcgcc ccggccgagc ccggccagcc
      301 gcgcgtactc ggcgaccgcc accaccccga gccccgccgc cagagcgaac gccccgggcg
      361 ggcccgcgag gaacgctccc aggaagagcg gcgccgccag cgcccaggta cgccaccgtc
      421 gccgcagctc ggtgcggagc cgcacccggg ccgggagggc ggcgacggcg accccgccga
      481 ggcccagcgc gccgccgacg acgggggccg cgcgagccag gagctcggcg gtggcgaggg
      541 cggcggtcat cgcgttctcc ccgtggtcgt ggtcgtggat gtggccggcg cgccgggcgg
      601 gcacggtgcg gcggggctga gcgcgggcgc gggcgcgggg cgggcgcgga gcccctcgcc
      661 cgacgcgcgc ccgtcgcggt cggccgcccc cagctcccgc cacaggcgcg ccccacgcag
      721 cacggccgtg gcggcggagc ccacggcgag caccgcgagg accggggcgt accagccggt
      781 ggcggcggcc acgacggcga gcaggcagcg ctccgtcttg ccgaccggcc cgccgttgag
      841 ccggacggcc ccggtggccg ccccggccag ggacacccag gagggcagcg tcgccgcgca
      901 ggcggccagc gcgaccagcc agcccggtgc caggggccag aaggccgcga cgaccacgag
      961 gtcggcggcc cggtcacccg tctcgttgag cagggcgccg cgccgggtgc tgcggcccgt
     1021 gtcgcgggcc agcgcgccgt cgaggttggc gcaggcgagc cgtgccgcga gcagcaccgc
     1081 gacgggcgcg cccgcccagc ccgccgggag cagcgcgagg gcggcgccgg ccgccgaggc
     1141 cgcgccgatc ccggcggcgg tgagggcgtc gggggagacc cggcgccggg cgagcgcccc
     1201 gcgcacaccg gcgagccggg ccgcgtacca gggcttgagt gcgtagaggc cgtacatggg
     1261 accgactctc ccgccggggt ggggccgccg gaacggtgcg ggtactcaga ggccctgagt
     1321 acgccggccg gggtgccgga gcggggcggt gtgggacggg ccactcttcc ggaggatgcc
     1381 gttctgtcca gggaaaaccc ggcgtgagct ggcgcggaaa gggcgcgcgg gcggctcacc
     1441 gggggcgcgt ccggaagaag ccgtctcaga tagtaggaag tccgagtaac tgtggagaca
     1501 gaagcgcgcc ccgggtctag ctttgtagga gccgaacgtc tcgctggaac cagcgaatga
     1561 cggatgcgcc ccgcgccacg agcaggcaat ccctgctggc ccggagcccc gtcccttccg
     1621 gcgcttcgac ctcccgtgcg atcgcccggt ggccgccctc gtggccgcgg gttccggtcg
     1681 cggggttctc gatcctggtg cgcggaccgg tccgcgccgt cccgccggcg ccgtaccggg
     1741 gccggagccg tcccgtgcgg cgccggcggt ccccggggcg gtccgaagcg tgtgccccgt
     1801 cccctcaggc ccagcgccac ccgccgttcc cggcgattcc gtccggcccc agcgatccca
     1861 gcgatctcaa aggagtctcc ccatgtccgc agagacgacc tccgccgccc gccgctcccg
     1921 ccgcgcccac cgggccaccg agaccgaccg ccgcaacgcc gccgcggccc tccagcgagc
     1981 cctggaccgc cgcgacaacg gcggcgccac cggtcactga gccgctcggc cccgcacccg
     2041 cccggccctc ggtgccgggc gggaggcgtg taccgccccg gactcgccga ccgtccgcat
     2101 catggacggt ccgtgtcacc ccgtgggacg aggagtaggg tgcgaccatg tctcgcagca
     2161 tcaatctcgc agtgatcccc ggtgacggca tcggccagga ggtcgtggcc cagggtctga
     2221 aggtcctcaa cgccgtcctc cccgaggatg tgaagctgga gaccaaggag tacgacctcg
     2281 gcgcgcgccg ctggcaccgt acgggggaga ccctgcccga cgcggagctg gaggcgctca
     2341 agcagcacga cgcgatcctc ctcggcgcca tcggcgaccc ctcggtcccc tccggcgtcc
     2401 tggagcgcgg cctgctgctg aagctccgct tcgccttcga ccacttcgtc aacctccgcc
     2461 cctcgaagct cttcccgaac accgccaccc cgctggccgg ccgtccggag atcgacttcg
     2521 tggtggtccg cgagggcacc gagggcccgt acacgggcaa cggcggctcg ctgcgcaccg
     2581 gcacccccgc cgaggtcgcc accgaggtca gcgtcaacac cgcgtacggc gtggagcgcg
     2641 tcgtccgcga cgccttcgcc cgcgcccagg cacgccctcg caagaagctc acgctggtcc
     2701 acaagaacaa cgtgctggtc ttcgccgggc acctctggaa gaacaccttc gacaaggtcg
     2761 ccgccgagta ccccgacgtc gccaccgact acctgcacgt cgacgccgcg acgatcttct
     2821 tcgtcaccca gccggagcgg ttcgacgtca tcgtcaccga caacctcttc ggcgacatca
     2881 tcaccgacct cgccgcggcc gtcaccggcg gcatcggcct ggccgcctcc ggcaacgtca
     2941 acccgacggg tgagttcccg tcgatgttcg aaccggtcca cggctccgcc cccgacatcg
     3001 ccggacaggg caaggccgac ccgaccgcca ccatcctctc cgtcgccctc ctgctgcggc
     3061 acctcggcta cgaggccgag gccgcccgca tcgaggaggc cgtctccgcc gacctcgcgg
     3121 agcgcgacgg caccgcgcgg tccaccgacg ccgtcggcga cgcgctcgcc ggacgagtag
     3181 ccggctgacc cggcgcacgc accccgaagc cgccgggtcc ccacgggaca acccggcggc
     3241 ttccccatgg gcggccccgg gtgccggcac ccagagcccg cgctcacccc gtcccgcccg
     3301 cgtaccgccc ccgcgccgtg cgcgccgcgg ccccgcgccc accgtttcgt cctcccgttt
     3361 ccccaccgtc ctccgcccgg cgcgtcgccg cacgcgacac ggacggcggg ggaggtggcc
     3421 tccccggcgt tccctcaccg ccccttccgg cgcgataatc gaacgtgggg ccgcggagaa
     3481 tgaggcgata ccggacgtcc gtgtggcacg cagcggaccg gagtgcgaga cagcaccccg
     3541 gccgcacgcc acgcagaggt acgggcgtga gcgcggtccg tcaccaccac acgtgaagga
     3601 caccactcat gacgacgccg acgatcgaac tgaagccctc cgcgcacccg ctcccggcgg
     3661 ccgagcgcga ggcgatcctc gcccgccccg gcttcggccg gcacttcacc gaccacatgg
     3721 tcaccgtgaa gtggaccgag ggccgcggct ggcacgacgg ccagctcgtc ccctacggac
     3781 cgctctccct cgaccccgcc accaacgtcc tgcactacgc ccaggagatc ttcgagggcc
     3841 tgaaggcgta ccgccgcccc gacggctccg tggcgacgtt ccgccccgac gccaacgccc
     3901 gccgcttcca ggcctccgcg cgccgtctgg ccatgcccga gctgcccgtc gagaccttca
     3961 tcgaggcgtg cgacctgctg gtcgcccagg acaaggcatg ggtcccgccg cacggcggtg
     4021 aggagtcgct ctacctgcgg cccttcatga tcgccacgga ggtcggcctc ggcgtcaggc
     4081 ccgccgacga gtacctcttc gtggtcatcg cctccccggc cggcgcgtac ttccccggcg
     4141 gcgtcaagcc cgtctccatc tggctctccg agaaccgcgt ccgcgccgtc cccggcggcg
     4201 tcggcgacgc caagaccggc ggcaactacg ccgcctccct cctcgcccag gccgaggccg
     4261 ccgccgaggg ctgcgaccag gtcgcctacc tcgacgccgt cgagcacaag tgggtcgagg
     4321 aactgggcgg catgaacctc tgcttcgtct acggcgaccg tctcgtcacc cccgccctca
     4381 ccggctccct cctcgccggc gtcacccgtg acaccctcct ctccctcgcc gccgacctcg
     4441 gccaccaggc ggaggagggt cgcgtctcca tcgaccagtg gcgcgaggac agccgcagcg
     4501 gcgccctcac cgaggtcttc gcctgcggca ccgccgccgt catcaccccc gtcggcaggg
     4561 tcaagaccgc caccgacgag tggacccagg gcgacggtga acccggcgag gtcaccctcc
     4621 gcctccgcga ggccctcctc gccctccaga cggggcgcgc ggaggaccgg cacgggtgga
     4681 tgcacccgct gggctgaacc tgatcaccga agagcggccc cgccggtccg agtgcggacc
     4741 ggcggggccg ctcttcgccg ggcccgagcg cggggtgctc caggcagggt cgcgccgcct
     4801 ggggaccggc acggccggcg cggtggggac ggaggctcgg ccgctcatgc gatggcccga
     4861 tccggttgcc ggagaagggc cggaaaccgg cgtgtttccc aggtgattga tggggagata
     4921 cgaccggtcg caacactgag taacaagagg tacgcatgag gtggaagcca gaggtcctcc
     4981 aggaactctc aggcatacgg gaagcgctgc gaacggctct ggaggccgcg cagcggtgcc
     5041 atgaatcaca gcaaggtctg gccgtgtcgc acacggaggc gaccggacag tggaaggaag
     5101 cgctggaaca gacgcagggg gagctgaagg ggctgcgggg agagacccgg cagggcctcc
     5161 gcctccagac ggaggccaac gccgacctgc gcgccatccg ggagggcgtg gccgagctgt
     5221 ccgccgtcgt tccgctcctc cgcgcactcg cggaacgaga ccgggcgacc cagcccgagg
     5281 cggcttcggg ggcgggcggc acgaaggccg ttcaccgggc ggacgggcgg gacgccttcg
     5341 cccacggtgg gaacgaacag catccggcag ccggcggcat ttctcggggg gacgacatgg
     5401 cagacctcga cggcggcgag cgcccgccgc accacgacga cctgaaggcg gcgatctggg
     5461 ccgtctaccg aggggacggg ccgcaggccg ccgcgcccgc ggcgccgcac ccctgcggtc
     5521 cgggccgctc gggacaggcg gggctcggcc ccgagggcga gcacgggctg ctgctgcttc
     5581 gggcagccgg tctcgcctcc gccgagctcc tcgcgcaccg cgacacctgg gagtggttcg
     5641 ccgacctcgc cgtcggacac cagcacttcc ggcatccctt ccaggtcgag gagaccaagg
     5701 acggacgcgt ccggacctcg ctgtcgggac gctccctggt ggccgccctg atcgggctgt
     5761 gggagaggat cgagaaggcc cccgtgaaca cggtggactg ggccatggcc accgcctact
     5821 accagcgggt ggccggtcgg ctggtcaacc tcaccagcca gggcggggtc atccgcatca
     5881 tcctggacga cggagcggac gacgcggcgg aggactgacc tcccgggggc ctgtggggac
     5941 tgaccttccc gagacctgtg tgggccggcc tcccgggaac ctgtggggac tggccccccc
     6001 cgggaacccg tggcgaccga cctcccggga agcccagggg gcggacctcg tgggacccca
     6061 ggggacggat ctcgtgggaa cccccgtggg gccctggcct gacgacggca cgggccccac
     6121 gcctcgcggc gtcttcgtac cgggggtgac gccctacccg tgggcggagc cttcgggggc
     6181 tctcggccgc gcgggcggag tccccgggac gagccgagcg cggaccggaa gccggacgag
     6241 ggggcgaggg ggaaggacgt gggattcgct gtgcggaccc tcgcgccttt cgccccctcc
     6301 acccgccgca cgggagacgc cgcgttcgca tcctgagacg ggcgaccaga ggtcgggcgc
     6361 cctgtggaag actggtcccg tgcccacgtt cgccatgatt atcggcagca ggcgcgccgg
     6421 tccgcagtga ccgccccgca ccaccacgtg cgacgcggcc accgtgcccc agacccgcgc
     6481 gcagacctct cgcacccgcg aggggtcttt tcgtttgtcg gccccgaccg ggccgcggcg
     6541 aggcgcacga gaggatgggg gcaagtggag ccaagcattc cggagccact cacccgacag
     6601 gagtcaccac cgcatgacca gccaggccac ccccgaggaa cccgctgacc gcgccccgtc
     6661 ggccgcgacg gaaccgcagg tcgcgcgcga cgtacggggc ggtgacgggg cgcgccccgc
     6721 gtccgccgga acccccgtcg ccgtgccgga caccgccgcc gtggacgccg ccgtcgcgcg
     6781 ccccctgcac atcttcgaca ccacgctccg cgacggcgcc cagcgcgagg gcatcaacct
     6841 cagcgtcgcc gacaagctga cgatcgcccg gcacctggac gacttcgggg tgggcttcat
     6901 cgagggcggc tggcccgggg cgaacccgcg cgacaccgag ttcttcgccc gcgcccgcga
     6961 ggagatcacc ttccgcaacg cgcaactcgt cgccttcggc gcgacccgcc gcgcgggcgg
     7021 cagcgccgcc gacgacctcc aggtcaaggc actcctcgac tcgggtgccc cggtcgtcac
     7081 cctggtcgcc aaggcgcacg accgccacgt cgagctggcc ctgcgcacca ccctcgacga
     7141 gaacctcgcc atggtccgcg acaccgtggc gtacctgcgc gaccagggcc gccgggtctt
     7201 cgtcgactgc gagcacttct tcgacggcta cgccgccaac ccggcgtacg ccaagtcggt
     7261 ggtccgggcc gcgagcgagg cgggcgccga tgtcgtcgtc ctctgcgaca ccaacggcgg
     7321 gatgctgccc gcgcagatcc aggccgtcac cgccaccgtc ctcgccgaca ccggtgcacg
     7381 cctcggcgtc cacgcccagg acgacaccgg ctgcgccgtg gccaacaccc tcgccgccgt
     7441 cgacgcgggc gccacccacg tccagtgcac cgccaacggc tacggcgaac gcgtcggcaa
     7501 cgccaacctc ttcccggtcg tcgccgccct ggagctgaag tacggccgca ccgtcctgcc
     7561 cgagggcgcc ctcgccgaga tgacccgcat ctcgcacgcc atcgccgagg tcgtcaacct
     7621 caccccctcc acgcaccagc cctacgtcgg cgtctccgcc ttcgcccaca aggccggcct
     7681 gcacgcctcc gcgatcaagg tcgatcccga cctgtaccag cacatcgacc cggagctggt
     7741 cggcaaccgc atccggatgc tcgtctccga catggccggc cgcgcctcca tcgagctgaa
     7801 gggcaaggag ctggggatcg acctcggcga ggaccgtgcc ctggtcggcc gtgtcgtgga
     7861 gcgggtcaag gagcgcgagc tggccggcta ctcctacgag gccgccgacg cctccttcga
     7921 actcctcctc cgcgacgagc tgcgccgcgg tgcccacggg ggagcggagg gcgaggcccc
     7981 gtcccggttc ttccgcgtcg agtcgtggcg ggcgatcacc gaggaccgtc ccgacggcac
     8041 gcacgccaac gaggcgaccg tgaagctctg ggccaagggc gagcgcatcc tcgccaccgc
     8101 cgagggcaac ggccccgtca acgccctgga ccgcgccctg cgcgtcgccc tggagcggat
     8161 ctatccgcag ctcgccaagt tcgaactgcg ggactacaag gtccgcatcc tggagggccg
     8221 ctccggcacc gagtccacca cccgggtcct gatctccacc ggtgacgggg acggcgagtg
     8281 gtccacggtc ggcgtcgccg agaacgtcat cgccgcctcc tggcacgccc tggaggacgc
     8341 ctacacctac ggcctgctcc gggccggcgt cgcgcccgtc gagtagtccc cgccgaggcg
     8401 gcggggccct ccccggcccc gccgcccggt cgcgtccgcc gccccgcctc gcgggcctcc
     8461 cgcccgcccg tccgacgcgc ttcgccccga cccgggttag cgtgggggta tgaggcgagc
     8521 cgcagtccgc cagtccgtac gccggggcgc cctcatggtg tccgggcctc ttctcgtgtt
     8581 gggcaccgcc ggagcgacgg ccgtgcccgc cgcggccgcg ccgtccgcgc actccccggc
     8641 cgtcgccgcc gccccggagc gggcccccgg ccgcgcgacc gtctccgagg tcgccacggc
     8701 ctggcgcgag ggtcccgtct tcgtggaccc ggacgtctcg gaccagctct ccgacgtcca
     8761 ggcgcgcgat ctctcccagg agatccagga gagcgacaag gcgatcttcg tcgcggtcct
     8821 ccccgccacc ttcaccgacg acgtcgaccg gacgatgaac gacctgcgcg gcgacaccgg
     8881 catcaccggc ctgtacgtgc tgcgcatcgg tgacgacctg cacgtccgcg ccgaccggtc
     8941 ggtcctgtcc ccgcaggcca cccagaacct ccagtcccgg ttccagggca ccaccccggc
     9001 tgccgaccag ctctccggcc tggtcggcaa cgccacccag aacatgggcg gccgcgcccc
     9061 cgcctcctgg tccgcccgcg aaggcgtacc cggctcgacc tggctcggcc tcggcatcgc
     9121 cgccgtggtc gtcggcggtg ccgcctacac gctgacgcgg cgtaccaaga accggcgtgc
     9181 gcaggcccag cgggaggcgc tcgacaagct gcgggtggtg gtggacgagg acatcaccgc
     9241 gttcggcgaa gagctggagc ggctcgactt ccggccctcg gagcccggcg ccaccgacga
     9301 gatgcgcggc gactacgagc gcgccctcga cgcgtacgag aacgccaagt ccctcatgga
     9361 ccacgcgggg aaacccgagg acgtgcggga ggtgaccaag gcgctggagg acggccggtt
     9421 cgcgctcgcc gtgctcgacg cccgccgcga tggccgcgaa ctgcccgtgc gccgctcgcc
     9481 gtgcttcttc gacccgcgcc acggcctctc ggtcgccgac gtcacctggg ccccggccgg
     9541 cggcgcgccc cgagaggtgc ccgtctgcgc ggcggaccag gcgcggctgg agcagggcga
     9601 ggcgcccgag atccgcaccg tcgagtccga cgggggaggc cgccgcccgt actgggaggc
     9661 aggtccggcg tacggcccgt gggcgggcgg ctacttcggt ggcggcctgc tgccgggcct
     9721 gctcgccggc acgatgctcg gccacatgat gatgaccccc gcctacgccg ccgactacgg
     9781 ctcggccgag ggcttcggcg acggcggggc gggcggcggt tacgagggcg gcgacgtctc
     9841 cggctccgac ttcgaccccg gcgacttcgg cggtggcttc ggcgacggcg gcggtttcgg
     9901 cggtggaggc ggcgacttcg gtggcggctt ctgaccccgg cggctcagcg gtgacgagtc
     9961 cgggggcgcc cgcagcacga agcggcgccc ccggcccggc tcaccccccg gcgaacaccc
    10021 gggcggccgc cgtgcccagc gtcgaggggc cgagcccgtt gggtccgatc ccgcgcggcg
    10081 cggcctcgat cacgcgccgc acgccggggg agtggtggct caggtcctcc tccttgtacc
    10141 gcacgcagcc ccggtgccag gtcaggatgg ccgacagcca gttctccaac tggcgcacat
    10201 acccgtccag caccttcctg gccgccgcgt ccagttggaa atcctcgtac agcacgggca
    10261 gttcgtgggc gacgatgtgc tggaactgtt ccagccgcgc gttcatcagc gcgtccacgt
    10321 acgccagccc ggtcgggtag tcgcagtcga agaagttctg ggtgacgagg acggcgttgt
    10381 ggatctcgcc ctcgaactcc acttccttct ggtaagagaa gacgtcgttg atcagtgcgc
    10441 cgtagtccga gacggccttc tccatcgcct ggacggtgcc cgagcggtac acctcctccg
    10501 gcacgatgtt gccgtggcgc agcctgcaca ggctcatcgt caggtccgag ccgaaggtgg
    10561 cacggcgcat ctccatgtag tcgatcgggt cggggatgcg gccgatcgcc tggttgtcca
    10621 gctcccagac ccagctgtcg agcatgacct cgatggtctt acggaactcg cggcgcgcct
    10681 tctccggcat cgccgaggcg gtccgcaccc acaggtcggc gagcgagcgc tccagggcac
    10741 tggtcggcac cggccccgcc gacggctgct cgaccggcat gaagtcccgc agccggtccg
    10801 tgcagacctt ggccccggcg aagttccggg tgcggccgaa gacggccggg tagtagtcgt
    10861 cgccgtacgt gccccaggtc agccactgcg aggcgaggtc cagctcctcc aggtcggctt
    10921 ccgggtgcag cccggccgcg cagagcggga agtcgtaccc ggccagcgcc tcctcgtccc
    10981 acacgtccga accgggcacc cccggctgcg gcacgagcag ccccatccgg tgcgcccact
    11041 ccaccgtgtc gacccgggac tgttccatcg ccggcgagag ccgcgtcggg aacggaagct
    11101 tgaagtccgg cagcagggag gccccggtcc tctggtacgg cacgtgcgag aagctgcgcg
    11161 cccgctgccg cgccggacgc ccgaagaacg accgcacgtc cagcgcggag gtgcccagcg
    11221 tcccgcccag cagcgccgcc gccagcgccc ccggcgaacc acccggtgtc ggcggtgcct
    11281 ccccgccgtc gaccgcgccc tcgttcatgt accggctgga gcgcatgtgc cactcgtggc
    11341 cgcccgactg ccagtcctgg agccccttca cgtacgccag caccgaggcg gactcggccg
    11401 gattcagccc cttgtcggcg aagagcggcc ccagttcggt cagcgcggtg ttctcgaact
    11461 gctggagccg tgaggtcagc aggtcgttga cggcctcggc cgcctcctgc gtggtgcact
    11521 ccaggaaccg ttccagcacg aggacgccgt tgctcagctc gccctcctcc tcgacctccc
    11581 gctggtagga gaagaggtcg ttgcgcaggt ggacgccgtc cgagaaggcg tcggtcagca
    11641 cgcgcagggg ccgcgagtac gccaccgcct ccggcacctc ggcctgcgcc gcgtactcga
    11701 tcagccccgc cgaccacggc gcgccgccga ccttgcggcg catctcgatg tactccagcg
    11761 ggttggagac gcggcccgcg ttgatgttgg acagctccca catcgactcg ttgagcaggt
    11821 tctccgtgga gagcgcgaag cggcgccgcc agtcctcgga catcgccgga accgtccgcg
    11881 cccacaggtc cgcgagcccc gcctccaccg gattccgagg ctccgggaaa ccgtcggcca
    11941 gatccatcgg catgaacgcc ggcagccgct ccaggtacgc cttcgcgccc tcacggtcct
    12001 gcgtccgctt gaacagttcc aggaagtggt cgtcgaagaa gaagacccac acgtaccagt
    12061 cggtcaccag cgacaacgcc ggcccgtcgc agtccggatg cgtgtacgcg cacagcagcg
    12121 cgtagtcatg ggcctccagg tcggccaggt cccagacgcc cgacccctcc agcatcccca
    12181 tctcgtccgc ccacacccgg gcgtgcgcgc gcgcctcttc cagatggggg ttgagccgcg
    12241 ccgggtacgg cacgtagaaa tcgggcagga caaagggctg tgtcacagtc gggccttcca
    12301 cacggtgatt tcggcggccc gatcactacc cgcccgtccg accggtcagc cggacggcgg
    12361 tgttgtcata cgagtggacc ggcggtcgcg tgtacgaacg ccgcccaggc ggcgggggcg
    12421 acgtcgagga cggggcctgc cgggaccttg gagtcgcgga cgtggacggt ggtggggtgg
    12481 gcggcgacct ctacgcagtt gccgccctcg ctcccgctgt agctggactt gcgccagtcg
    12541 taggcgacct cgatgcagtt gccacccgcg tcgctgctgt agctggactt gaaccaagag
    12601 agtggctggc taagcgaagg ggcgccggtc atttcactcc aagcagtgtg ttcagcaggt
    12661 cctttgtctt ctgaggtgag agggcctgcg cccgcagcat cccatacttc tgttggtacg
    12721 cactgacctc atcttggtcg tccaccatga agcccctgtg gtgtccctcg atgtaggcga
    12781 ggtggtcgtg gtccggcgtt tccagcagaa cgaggggacc ggccagccct gcgtgggcgt
    12841 cagtgttcgt tggcatgact tggagactca gacagggcag gtcggcgcag tctcggagat
    12901 gctggatctg ttgtgacatc gcctgcgggt cgcccaagtg ccttagcagc acgctctcct
    12961 caatgatgaa gctcatcatc ggaggaatat cgcgagacag tatctgcttc ctgtcgacac
    13021 gggcttgcac cgcttcttcc aggccctgcg ttgtcaaggg cggatacgcg ttgccgaaca
    13081 cggtccgtgc gtattccgac gtttgcagca ggccggggat gacgtggctc tcgtacgaga
    13141 ggatggtgac ggccgtttgc tcgtgctcga tgaagtcctg ggcgaacagc ggataccgct
    13201 cgtgcgtcgg gatcgtcgac accgctgtgc tcagtgcgcg tttggtctcc aggatcgtgt
    13261 ccagccgctc ggccaagtcg gcctgtagcc gtcgtctgcc ctgctcgacg gaggagaccg
    13321 tgtcctcgcc gaccctcgcc aggtccgcca gttgcccctg ggtcagcccc gccacccgcc
    13381 ggaactcggc cagttgtttg ccgagcactt cccacgacgt gaccttcttg ctggacttct
    13441 ttcgctgctg catacgcact ccctctcccg acgcgccccg tcgcgcaccc gacacgaccc
    13501 gtacaacgga tttgtacggg tcgacgccct gcacaaggct agtgacgttg ggtgacctta
    13561 ggagggtgga aaccgaaacc cgactccccg cgcgctgcga gcgcttctac cgccgcgagc
    13621 gccgatccgt ccccgcagcc agggacttca ccgccgccgt gctggacgac tgggacgccc
    13681 gcgtgccccg cgacgacgtc ttgctctgcg tgagcgaact ggccaccaac gccctgctcc
    13741 acggcgtccc gccggggcgc ggcttccggc tcttcgtgct ccgggccgac gacggcggcg
    13801 tacgcgtcga ggtccacgac agtggcgacg ggcaccccgc gacccgcgcc cccggcgacg
    13861 aggccgagtc cggccggggc ctgctcctgg tctccgccct cgccgacgac tggggggtgg
    13921 gggagcgcga cccgggcaag agcgtctggt gctccttccg tcctctgccc gtccaccact
    13981 tgggaaggtg acccccctca gttcctccac cgggtgtcgg gtccgccggg cggcctcgac
    14041 ggagcgccgg cggagggggc ttgtgctcgg caagggaccg ccgaggcggc cggagccgct
    14101 cggcccccag aacggccggc ccccggcccc gggtgccgtc gccgggtacc gcgtggtccc
    14161 gccgggccgc gccgccctca ccgttccggc gcctccgcac ggtcacctcg gcccggtgac
    14221 cggccgcgac cccctcccgg aggccgccgg ccagtgcctc ggcgacgtga tcgcggccag
    14281 tgtgcggacg tgcgcgccga agggggcgaa acctcgcctc accagggccc ctcatcccgg
    14341 tacgacgcgg gcgccgggtc ccagagctgg tcgtgccggg ccaccacgcg ccgcagttcg
    14401 cgcgccccgc gccgtgacag ggcgcgggcg acccggtcca gcgactcccg ggcctcccac
    14461 gggtctgggc agcagtaaca gggggcgcac ccggcgtgcg gccacgtgcg ccccctcggc
    14521 aacctcacat gcccggccca ggcgcgtacg gcctcggcca cggcgcccgg ccacagacaa
    14581 ttccgcgagc gctccagtcg ggccacctcg gccgaggtcc cgcccgacag cccgtcgatc
    14641 acgggtgact tctcgtaggg cctgcgcggc cggggaagtc cggctcgcac cctgcccggc
    14701 ggcttacgcg gcacgggcct ttcggcaggt cgtcacaagg gccagcctgg cacggagccg
    14761 ctccggccgt ccgatcattt ttccggggta ccaccttccc gggttcgggc tcgtcggggc
    14821 gcacggtccc ggcttgaccc tcacgcggcg tgaggccgga cgctggggca catgagcgac
    14881 tactacgacg cgttcgagat cagtcccgtg cccgctcccg gccccgacgc ggtgccgccg
    14941 gagcccttcc ggggcatcta cgggatgccc gccttcgtga acgtccccac gaccgacctg
    15001 gcggcgtcgg tggagttctg gacccggggt ctcggcttct tcgagctgtt cgtggtcccc
    15061 ggcacgctcg tgcatctgcg ccggtgggcc ttccaggacg tgctgctggt cgcggcgccg
    15121 agcgtcccgg agcagccgcc cgcgatgagc ttcagcttct ccggcgtgct cgaccaggtc
    15181 gactccctcg ccgcggcctg ccgcgcgctg cgcccggacg cggtcgacgg gccccgggac
    15241 acgccctgga acacccgcga cgtggaggtc gtcacccccg agaacgcacg ggtcgtcctc
    15301 accgccgcga agcccttcga cccggccggc caggaggcgc ggaacctcgc ggccatgggc
    15361 atcaccccgc ccggcgacgg tcccggcggg aggcatggct gacacccctg gcgccggcgg
    15421 cccggccgtg gggcaggtct cggcgcgcct ggacgtgacg gtccgcacgc tgccgccgcc
    15481 gtggccggcg cccctcgcga ccggtgggcc cgcaccggtc gctcgtacgg cccggggcac
    15541 tccggcgcgc cctgtcgctc cgccgcccgc accgggtcgg cgcccgcacc gggtcggcgc
    15601 cggccggtcc accccgtcgt cacgcgtacg gaccgtccca ccgcccggcg ccggcagcgc
    15661 ggccccggcc cggacgcctc agtgatcaca tcgtgtcccg caccgcgcac aacctcgcac
    15721 ggccctctca tgtcccacca ttggccgaga gaccgagctc cggccggggc gcctgcgcgc
    15781 ctgtccacgc ggtggcgaga ggtcgggtcg ggttcgatga cgcggaagac gatgtggaga
    15841 acggcggtgg ccggcggagc ggcggtcgtg ttcaccggac tgacggcggt gccggccggg
    15901 gcggcggagg gcggtgtctc cttcaccagg gtcaaggtga acagcggcaa gccgatcgtg
    15961 atcggggtga aggaagaggt cgaggtaccc gcctccggcc ggatgacgac caaactcacg
    16021 ttcaagggcg tccccatggt gcacccctac cgggggaagc tcgggaaggg ggaagagctc
    16081 tggagcgccc tcgggggagg cgaccccgag ggcgtggacc ccgtgaaggg cgtctacgac
    16141 ttcgccgtgg cgttctccat ccacccgcgg cacgccggcc tcaagaacaa ggacgccggc
    16201 acctggaaga cgtgcgcccg gatctcgctg gccggcggcg gccacgacgt ggacgacgag
    16261 aacctgccgc tacaggtcaa gcgggccacc cgcctcaccg tcaacgcctc gccggagccg
    16321 gtgaccaagg gcaagaccct caccgtgacc gggaccgtca cccgcgccga ctgggacaag
    16381 cacacctacc agggctacgc cggccgcacc gtcagcctcc agttcaggcc cgcgggagcc
    16441 tcctcgtaca agacggtcaa gaaggcgagg tcgaacagca agggcgccct caagaccacg
    16501 gtcaaggcca ccgggacggg gacgtggcgc tggacgtacc acggcaactc gacctccgga
    16561 gcgaggtcgt cgagcgggga ccacgtcgcc gtgaagtagc agcgggtagc tcccgtccgg
    16621 cccccgcgaa ggcgaccgct gcggaacagg ccgcccgggt gggcgatcag acgggcggcg
    16681 gggccggatt cctcctccgc accgaggact ccgcgggcga gcacgccccg ccgcgcgccg
    16741 ccggggcggc cttcgaggag gcaccccggc gggagacaca cgggatcgtg gccgtcttcc
    16801 gtgacccgca cggggaccgg tcgggcctgc ttcaggtggg gtgcgtaccg gcccggcagg
    16861 gcgtcaggaa gccgccgccg gcgccggagc gggggtcagc ggctcgccgt tcagctcggt
    16921 ctcgtccttg agggaccacc acagttcgcc gtcgcacgtc aggtagggca cccaggtgcc
    16981 gccgacggca ccgcccttct ccagaacctc cgcgacctcg gtgaggtacg ccgacagcga
    17041 cggccagccg ccttcgaaca cgccgcagtc gtcgtggtac gccatgccca gacggccctg
    17101 gtccggaccg gggcgcatgt cgatgatctg ggcgtcgccg tcgctctgcg cccacgggac
    17161 ccactgcggg tgccaccacg gctcctcgtc ctcgggctcc cggccctccc cgtcggcgcg
    17221 gttggcctcg tcgatctcca cgcacatccg ccagtgaccg acgatctcgg agaccggcag
    17281 gggcgggcgg accggcaggc agttggccca gtggcgcagt ccgtcatggc aggcgagcga
    17341 ggcgagcaga tcggccggga accgcacccc cagctccgcc tgggccgcct cgaccgccgc
    17401 cggaccggcg ggcggggcca actcctcgta ggaatcgggt gcgtgggcgc gcatccacgc
    17461 gtcgatgcgc gcccacgcct cccgcaccgc ctcggcgcgc gcctcgtccc cggccgtcct
    17521 cgtcccgtcg tcgctcatac gaccgatccc accacacgcc accgacagga ggccggccgg
    17581 acgtcagccc cggggcgtac ggcccccgcg gtttcgcccg tgccgcggtc ccggcccgcc
    17641 ggggcggttc cgtcgcgggc ggccatcctg accgctccgg ccggacgggg cgccctccac
    17701 gccaggccgc tccgcacgag gagcggccgg actgccgccg gacgtcgcgc aactcgacgg
    17761 ggaccctgcc ggccccgggg ctgatacggg cgacgaccgc cacgtggacg gcgaacaccg
    17821 cgctcgggcg gaccgttcct cgtcaggcgc gaggaaggtc ttcaggccgc cggtgcgcgc
    17881 ggcagtagtg gtgtccggcg ccaggccccg ccctcgcgac gaggcggcgg agcccgcgcc
    17941 cgcggggtgc gggccggcct gccccagggc cccgtaccgg ccgggcctca ccccgtccgt
    18001 cgctccgcct ccagcgtctc gcggagacgc tccagggtgc ggcgcatggt ctctgcgttg
    18061 tgcgcgctcc ggtcccagac gccgctgacc gccgaaccga ggaaccacag gagccggttc
    18121 cgctggtcca cggccgtctc ggtcacctcg gtcgcggtgc cgtcgccgac cggacggaag
    18181 cggtagtccc aggtcgccac cggcatcccc cagaaccgca cccggaaggt gaaccgttca
    18241 ccgggccgcg ccaccatcac ccggcagcgc gtcgaccaac tgcgcccgct cgggcctttg
    18301 ttgacaccct tgaactcggc gcccaccggt gcgggcccga cgcccgccgc cgtccgcacg
    18361 cactccggac tccaccggcc catcgacgcc acgtcggcga cccgctcgta gaccgccttc
    18421 ggctccgcct cgatcacggc cgccacggag acctccgctg tgctcctcac gtccctcaac
    18481 cccctcagtc gtacaacgcg tcagcaggac caccccagcc aaccaaagcc gccccggccc
    18541 ggccaccctc cagcccccgg ggagaccacc ctcacgtgta ctaccgtccg gaggatgagc
    18601 gagaacgtgt acgtgggtga cgcccccacg gaggccgcgc tggacgccgg gtggatcatg
    18661 ggccacttca aggcgccgga cgacccgcgc cacaacgagg ccgtggagat caaatggggc
    18721 gtccacgagg ccggcgaccg acgcgccgcc tgggtgcggg gcgaggaacg gcaggcgctg
    18781 ctcgtcctcg tcagcggccg cttccgcatg gagttccccg gccgggacgt ggtcctgagt
    18841 gaacaggggc agtacgtgat ctggggcaag ggcgtcgacc actcctggga ggccgaggag
    18901 ccgtcggtcg tcatgacggt gcgctggccc tccgtgccgg gctaccgcgt cccggagacc
    18961 gcggccgggt agcgcgccgc cgtcccgcgc cgcgccccga cgcggccccc ccccggaccg
    19021 ccctctccgg gccacccccg tacggagcgg ggggacgacc ccggcgggga gcggtgagga
    19081 gagggcggag ggtggcgccg aggggtcggc ggagggcgcg tcggccgggg tgggcgagcg
    19141 gcatccgctc cgcccgcaca cccacgcgcc cgcctctcgg ctccgaccgt cagttacccg
    19201 ccaccgtccg cgccaccctt ggtgtcaccc gaacgtgcgg ggcgttccgg gggcgtgacc
    19261 agcgcattca cggcgggtca tggcggtcgt gacggtcacc ccggtcatgg acgtcaggac
    19321 gtcacggcgg tcgcggcgtg accgtcgccg cacggcggcc ccggcgggtg agacgggaga
    19381 ggggtggccg gccgggcaga gggccgagcg tgcgtgccgg gccggcgtgg agtcgcgggg
    19441 ctccggtgcc tgtccctcgg ggcgcttcgg tccgccggct cgccacgctc gcgaccagcg
    19501 gcgccccgtc ggcgggcggg gtgccggcgg accggtggag tggcgggcgg accgcccgcc
    19561 gccggccggc cgcacgcagg agcgcccgcc ctccggaagg gagggcgggc gcgctctcgg
    19621 ggctccaggg ccccgtgccc ctgtggttct gcgggtccgt gggccggggg tcgtccggcc
    19681 ggcccggccg ggaggggtca ggcgttcttg atcgccgaga tgtcgaaggc cagcttgatc
    19741 ttgtcggaga cgaggacgcc accggtctcc agggccgcgt tccaggtcag gccccactcg
    19801 gagcgcagga tggaggcggt gccctcgaaa ccgacgcgct cgttgccgaa cgggtccttg
    19861 gcggcgccgt tgaactccag gtcgatggag agcggccggg tggtgccgag gatggtcagg
    19921 tcgccggtga tccggtagtc gtccccgccg agcgcctccg ccttcgtgga gcggaaggtc
    19981 atctgcggga actcgtcggt cttgaagaag tcggcgctct tgaggtgacc gtcgcggtcg
    20041 gcgttgccgg tgtcgatcga gtccatggtc acgtcgatcc gggcggagga gttcgccggg
    20101 tccgcaccgt ccagctccag cgtgccggtg aagtcggcga agccgccctt gacgttggtg
    20161 accatggcgt ggcgggccac gaagccgatc gtggtgtgcg ccgggtcgat cgtgtaggtg
    20221 ccggtcagcg cggccaggtc cgggttgacg gcgctggtcg cggcggtcgc ggcggtctcg
    20281 ttcttgcggc cgaagatgcc catggtgtgc tccttggggg acgtgctccg ggcggactcc
    20341 ggagcggggg agaagctgtt gaatgttcaa cgagttcgac ggtaacgcgt ttccgttcaa
    20401 ctttcaacat ctccgctcgg gtgggtgctg aaccctggcc gaggccctct ggcgccgggc
    20461 cgggccggcc ggtgccggtg agcgcgttcc gggcttcggt ggcgcgcgga cgcacgcggt
    20521 cggggtgcgc ccccgagttg gctggaactg gtgggttgga ccccctggtg acacgcgtag
    20581 aactcgggca ctatgcctct gctccgcccc gtacggcctc cgcaccaccc ccacgcaccc
    20641 cccaccgccg cgtgccccgc acgccacgca aggaggaccc catgaagatc cgctcggcgc
    20701 tgagcgccct cgccctcgtc gcgggagccg ggttcggcgt catcggcacc gccaccgccg
    20761 ccaccgccgc tccggccccc gccggcgccg ccgccgagta cggcgcggcc gtcaccaaga
    20821 tcactcatgc ccaggccacc tcacggttct cctcctcagg gatcacgtgg tcgtcctcgg
    20881 gcggctgctc caaccgcaac gtctcgacct gcacctcgtt cgaccagttg aacctcgcct
    20941 cggcccaggg cgcccagacc ctcaagtcgg cgagcggctg tgccctgagg atcaccggcg
    21001 gcaccgagac cggccacgcg agcggcacct actcgcactg gaacggctac aagctcgatt
    21061 tcgccaaggc cacctgcctg aacaactacg tcaccggtca cttcacctac atcggccagc
    21121 gcggcgacgg cgccgcccag tacaagtccg cctctggcaa catctacgcc aacgagggca
    21181 accactggga cgtgaccttc cacaactgcg gcggctgctg accggcccgc cggaccccgg
    21241 tcctccggtg ggtgtcagcc gttcgggcgc gccaaggaac gccccgcccc gggcgcgtcc
    21301 gcttgtgggg tccctacggg ccgccgagcc gttcgcacgc tcctcgcctt tgtcggaatg
    21361 ccacaacgcg caccccccgc cagcagtcga atgcgttgcg taccccgatc ttcctgtgag
    21421 accgctccag gaaaacggcc tgaggactgt gaggagtcga cggcagattc ccggggcccg
    21481 gcttcgtaga gtcgctacat gaccgttttg gacgagacag ccgagtccgg gagcgagccc
    21541 gccgacgcac gtggccgcgt ggccgagctc cacgccctgc gccagcgggc cgagcagggt
    21601 ccgagtgaga aggcgacggc ggcgcagcgc gccaagggca agctgaccgc ccgcgagcgg
    21661 atcgccctgc tgctggacga gggctcgttc cgcgaggtcg agcagctccg caggcaccgg
    21721 gcaaccgggt tcggcctgga gcagaagaag ccgcacaccg atggtgtcat caccggctgg
    21781 ggcacggtcg agggccggac ggtcttcgtc tacgcgcacg acttccggat cttcggtggc
    21841 gcgctcggcg aggcccacgc cacgaagatc cacaagatca tggacatggc catcgcggcc
    21901 ggggcgccgc tggtctccct caacgacggc gcgggcgccc gcatccagga gggcgtctcc
    21961 gccctcgccg gatacggcgg catcttccag cgcaacacca aggcgtccgg ggtcatcccg
    22021 cagatcagcg tgatgctcgg cccgtgcgcg ggtggcgccg cctacagtcc ggcgctgacc
    22081 gacttcgtct tcatggtccg cgacacctcg cagatgttca tcaccggccc ggacgtggtc
    22141 cgcgcggtga ccggcgagga gatcagccag aacggcctgg gcggcgcgga cgtgcacgcc
    22201 gagacctccg gcgtctgcca cttcgcctac gacgacgagg agacgtgcct cgccgaggtg
    22261 cgctacctcc tctccctcct ccccca
//
