LOCUS       NZ_CP045704            21044 bp    DNA     linear   CON 03-SEP-2024
DEFINITION  Streptomyces rutgersensis strain NBH77 chromosome, complete genome.
ACCESSION   NZ_CP045704
VERSION     NZ_CP045704.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces rutgersensis
  ORGANISM  Streptomyces rutgersensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces diastaticus group.
REFERENCE   1  (bases 1 to 6848830)
  AUTHORS   Benaud,N., Edwards,R.J., Amos,T.G., D'Agostino,P.M.,
            Gutierrez-Chavez,C., Montgomery,K., Nicetic,I. and Ferrari,B.C.
  TITLE     Antarctic desert soil bacteria exhibit high novel natural product
            potential, evaluated through long-read genome sequencing and
            comparative genomics
  JOURNAL   Environ Microbiol 23 (7), 3646-3664 (2021)
   PUBMED   33140504
REFERENCE   2  (bases 1 to 6848830)
  AUTHORS   Benaud,N., Edwards,R.J. and Ferrari,B.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2019) School of Biotechnology and Biomolecular
            Sciences, University of New South Wales, Botany St, Sydney, NSW
            2052, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-DEC-2018
            Assembly Method                   :: FALCON v. v 1.8.6
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014216335.1-RS_2024_09_03
            Annotation Date                   :: 09/03/2024 04:34:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,921
            CDSs (total)                      :: 5,831
            Genes (coding)                    :: 5,642
            CDSs (with protein)               :: 5,642
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 189
            CDSs (without protein)            :: 189
            Pseudo Genes (ambiguous residues) :: 0 of 189
            Pseudo Genes (frameshifted)       :: 102 of 189
            Pseudo Genes (incomplete)         :: 130 of 189
            Pseudo Genes (internal stop)      :: 14 of 189
            Pseudo Genes (multiple problems)  :: 50 of 189
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:08:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4811384
            Orig. end                         :: 4832428
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045704.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Belinda Ferrari, QAP Lab
            4002, Bioscience South E26, UNSW Sydney, Australia 2052 (Quarantine
            regulated isolate).
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21044
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="13"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21044
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21044
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11044](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11044
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(105..518)
                     /locus_tag="F0345_RS20245"
                     /old_locus_tag="F0345_20280"
     CDS             complement(105..518)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="F0345_RS20245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20280"
                     /product="hypothetical protein"
                     /protein_id="WP_003950781.1"
                     /transl_table=11
                     /translation="MSPIAGEPGTQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLGCVFRLIDDSLEVTVSAPTTDGKAPERDTFAWTV
                     LSALAGKVDSSVAEDNTVSISLHKQRGAGPGPA"
     misc_feature    complement(649..662)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.89"
                     /tool="antismash"
     misc_feature    complement(655..668)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.69"
                     /tool="antismash"
     gene            complement(737..997)
                     /locus_tag="F0345_RS20250"
                     /old_locus_tag="F0345_20285"
     CDS             complement(737..997)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950782.1"
                     /locus_tag="F0345_RS20250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20285"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_100454719.1"
                     /transl_table=11
                     /translation="MNKCAHVAELPHPEPAPSADTCEECLEAGTHPVQLRKCLHCGHVA
                     CCDSSPHRHATAHFERSGHPVMRSAEPGESWRWCYADGSIV"
     gene            1077..2672
                     /locus_tag="F0345_RS20255"
                     /old_locus_tag="F0345_20290"
     CDS             1077..2672
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470744.1"
                     /locus_tag="F0345_RS20255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20290"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_100454721.1"
                     /transl_table=11
                     /translation="MDVLPLLLLVAGSTAVAGAARRTPVPAPLLLVTAGLLVSYVPGVP
                     HYTLDPEIVLPMVLPPLLYTAAMDSSYLDLRAQVRSVALLSVGYTLFATLAVGWAVHLV
                     VPDLPLTAALVLGAVVAPPDAVAATAVARRVGLPSRITTILQGESLVNDATAITAYRVA
                     VAAAVGESAGPLHAGAEFLVASLGGVAVGLVLMVPLHWLRTHLREPLLQNTLSLLIPFA
                     AYALAEYAHASGVLAVVVVALYLGHHSWQVDFATRLQEDAVWKMVAFVLESAVFALIGL
                     QLPLVVGGLGEYHAGQVLWYALAVFLLVVATRFVWTYPAVHLPRLLSRRVRAREPDPTW
                     KGPFVVAWAGMRGVVSLAVAFSIPHGVHEGGSFPYRNLILFLTFTTVIGTLVVQGLTLP
                     ALIRLLRLPGRDARAETLLEAQAQNAASEAAEHRLDALLTDPRNALPEPLADRLRAVLE
                     RRRNAVWERLGTVNPETGESVDDTYRRLARTVIASEREVFVALRDQRHIDDEMLRDLLR
                     RLDLEEAAAYREDE"
     gene            complement(2685..3665)
                     /locus_tag="F0345_RS20260"
                     /old_locus_tag="F0345_20295"
     CDS             complement(2685..3665)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893582.1"
                     /locus_tag="F0345_RS20260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20295"
                     /product="1-aminocyclopropane-1-carboxylate
                     deaminase/D-cysteine desulfhydrase"
                     /protein_id="WP_100454723.1"
                     /sec_met_domain="PALP (E-value: 9.7e-18, bitscore: 62.9,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIRRDPVPPSPGASEPRARDGRPGHEPARPLLPSPVRELREPAF
                     ERYGVRLLLKRDDLIHPDIPGNKWRKLAPVLDTADGRTVVTFGGAWSNHLRATAAAGRL
                     LGFPTVGVVRGEELAGRPLNASLARCRADGMRLAFVSRARYRRKDDPAVRDELVAEAAG
                     AGQAVRVVPEGGSDAAAVRACAVLGGELAALREDAPVAGVACGTGGTLAGLAAGLAPEQ
                     RAVGVAVLKGGFLGAEVAAHQRAAFGGQRGRWSVEDGFHHGGYARSSPELERFATAFEQ
                     RHGLPVERAYVAKLLHGLAALAADGRFRRGTAVAAVVTGPPFPRA"
     gene            complement(3697..4290)
                     /locus_tag="F0345_RS20265"
                     /old_locus_tag="F0345_20300"
     CDS             complement(3697..4290)
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414543.1"
                     /locus_tag="F0345_RS20265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20300"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_100454725.1"
                     /transl_table=11
                     /translation="MAPPMSADRFLKALKDEGVTVVEVGSWRSHNRNSKGAWGPVNGVM
                     IHHTVTSGSDRTVEICRKGHASLPGPLCHGVITKDGRVHLVGYGRANHAGLGDDDVLAA
                     VIAERAGYPPVNEANTDGNARFYGFECENLGDGKDPWPSAQLDAIERVSAAVCRVHGWN
                     ERSVIGHLEWQPGKVDPRGFTMASMRERIRGRLK"
     gene            complement(4493..4723)
                     /locus_tag="F0345_RS20270"
                     /old_locus_tag="F0345_20305"
     CDS             complement(4493..4723)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950786.1"
                     /locus_tag="F0345_RS20270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20305"
                     /product="hypothetical protein"
                     /protein_id="WP_100454727.1"
                     /transl_table=11
                     /translation="MAGFLDRAKEQAQRGLAQGKQKLDEVQVQRAGADLLKKLGSAYYA
                     EQRRGGDPRATQDALRALEQHIATHGEQGLR"
     gene            complement(4897..6120)
                     /locus_tag="F0345_RS20275"
                     /old_locus_tag="F0345_20310"
     CDS             complement(4897..6120)
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642378.1"
                     /locus_tag="F0345_RS20275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20310"
                     /product="globin domain-containing protein"
                     /protein_id="WP_100454729.1"
                     /transl_table=11
                     /translation="MLTERSAATVRATLPAVGAAIGEITGQFYDRLFADRPELLRDLFN
                     RGNQAAGTQRQALAGSIAAFAGHLLDQPDSRPDAMLARIAHKHASLGVTRDQYALVHRH
                     LFAAIADVLGEAATPEVAEAWDEVYWLMANALATHEERLMAEQNVLAGGTWRPWEVVAR
                     HDDTAEVAVLRLRPADGRPAAPYRAGQYVSVQAELPDGARQIRQYSLTGAPEGDERTIA
                     VKRVSGGPGPEGEVSGHLHARTRVGDVLDLSAPYGDLVLDRTPGADGRPAPLLLASAGI
                     GCTPVVAMLRELADSAYAGPVTVVHGDRTPATHPLRAPHTELTGRLADAEAHFWYEEHT
                     AGPGALTGRVDLKAVPVAPGTRAYLCGPLPFMRSVREQLLEQGVRPADIHYEVFGPDLW
                     LASAQPAA"
     gene            complement(6299..6760)
                     /locus_tag="F0345_RS20280"
                     /old_locus_tag="F0345_20315"
     CDS             complement(6299..6760)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950788.1"
                     /locus_tag="F0345_RS20280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20315"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_100454731.1"
                     /transl_table=11
                     /translation="MRLTRFTDLALRVLMRLAVEDPKATDDLPTTREVAAGMRVPYTHT
                     AKAVARLQRLGLIEARRGRGGGLALTEAGRSASVGTLVRELEGVGDVVECEGAEPCPLL
                     SACRLRGALRQAQESFFATLDPLTVGGLAAAPAGPVLLDIARSRSPDDT"
     misc_feature    6779..6795
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 23.78"
                     /tool="antismash"
     misc_feature    complement(6815..6829)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.35"
                     /tool="antismash"
     misc_feature    6816..6829
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.9"
                     /tool="antismash"
     misc_feature    6909..6923
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.34"
                     /tool="antismash"
     misc_feature    complement(6936..6951)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.47"
                     /tool="antismash"
     gene            6949..8355
                     /locus_tag="F0345_RS20285"
                     /old_locus_tag="F0345_20320"
     CDS             6949..8355
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="F0345_RS20285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20320"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_100454733.1"
                     /transl_table=11
                     /translation="MSVGEEIRAEQATPQQSLATSAARNLATTTKSVPQMQEISSRWLL
                     RTLPWVDVQGGTYRVNRRLSYSVGDGRVTFVKTGDRVQVIPAELGELPALRDFEEQDVL
                     TELASRCEQREFEAGETLASFGSRTDAVFLLAHGRVEKIGTGPYGDDSVLGVLADGAYF
                     GEQALTDPEAIWEYTARAATHCTVLVLPGDQVAQVAERAEPLAAHLRQLRSLPQQRTNK
                     YGEAPIDLSAGHVGEAVLPGTYVDYEASPREYELSVAQTVLRIHSRVADLYNQPMNQTE
                     HQLRLTVEALKERQEHELINNREFGLLNNCEYDQRLQPHAGVPGPDDMDELLSRRRGSK
                     LFLAHPRAIAAFGRECSRRGIYPESVEIAGNRLPAWRGVPIYPCNKIPVTEARTSSILC
                     MRTGEEDQGVIGLRQSGIPDEIEPSLSVRFMGISEQAIISYLVTTYYSAAVLVPDALGV
                     LENVEIGRWQ"
     misc_feature    complement(9074..9089)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.98"
                     /tool="antismash"
     gene            10001..11044
                     /locus_tag="F0345_RS20290"
                     /old_locus_tag="F0345_20325"
     CDS             10001..11044
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415521.1"
                     /locus_tag="F0345_RS20290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20325"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_100454740.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2e-60, bitscore:
                     202.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHTTQSRTHSHEAAEILDEARAVVGPELRRAVDTLPAPIRRVAR
                     YHFGWEDEAGSAAGANGGKAVRPALVLAAVHALGGRPERALRSAAAVELTHNFTLLHDD
                     VIDRDRTRRHRPTAWTVFGDADAILAGDALQSLAQQWLAEDPHPRAGAAVARLARCVVE
                     LCAGQHTDCALEERAPTEVALDECLTMAESKTGALLGCACALGALHADAGPEQIAALDA
                     FGREAGLAFQLIDDIIGIWGDPARTGKPAGADLTARKKSLPVVAALTSGTAAGAELAER
                     YAGPPEPDELARTVALVEAAGGRDWAQAEAADRMGRAVQQLALAVPDPARAGGLLSLAE
                     FVTRRSH"
     gene            11252..11848
                     /locus_tag="F0345_RS20295"
                     /old_locus_tag="F0345_20330"
     CDS             11252..11848
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950792.1"
                     /locus_tag="F0345_RS20295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20330"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_100454743.1"
                     /transl_table=11
                     /translation="MGVATRTAGAADRDRVAALLDTAFHHDPVSSWVFPEEEHRRAVHG
                     VFMGCFLDAALAGGRVDLLEDGSAAALWLSVPAGEPEEEDDMPALMRRTADPDNERAEL
                     VGRLTGAIHPTGRAHAYLLLVAVAPDRQGEGLGTALLTPVLEQCDRDGLPAYLEASSAR
                     SRELYLRLGFADRGEPLRLPEGPLMWPMWREPVTH"
     gene            complement(12123..12470)
                     /locus_tag="F0345_RS20300"
                     /old_locus_tag="F0345_20335"
     CDS             complement(12123..12470)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040156.4"
                     /locus_tag="F0345_RS20300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20335"
                     /product="DUF5713 family protein"
                     /protein_id="WP_308429910.1"
                     /transl_table=11
                     /translation="MGGIPIDGQRVAAEIPPRAPRRLLVPGPGPGQGRRDPHRPARADR
                     GERPPGLHALYALTDAATKAFNALETGSEAAGNEIETTAHEEVAEEFRLIATAHGYLDA
                     DPERLVSARDW"
     misc_feature    complement(12653..12666)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.41"
                     /tool="antismash"
     misc_feature    complement(12653..12669)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.24"
                     /tool="antismash"
     gene            12755..13750
                     /locus_tag="F0345_RS20305"
                     /old_locus_tag="F0345_20340"
     CDS             12755..13750
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642366.1"
                     /locus_tag="F0345_RS20305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20340"
                     /product="DUF1648 domain-containing protein"
                     /protein_id="WP_100454745.1"
                     /transl_table=11
                     /translation="MTATGRRARVPRRLVALVALPFVAASALAAGVQAAASDRLPARLA
                     VHFGAGGVPDRFESPAQFLVTVAALLLLGGAAWTVLVVRGARGGGAGTGMATAMGWGLA
                     AFLGSISVLLLQLNADAADPAEVRLPLWHFGAALAVALTAGFLGHALVRGLVPAWPPDR
                     ESSGAERLDLPRHGRAGWARRTGSWPLLLAGLVTLCVAAALLLVSGTSWWAGIVLLLSG
                     LPLVLMAQADVTVDQRGLTVRLSGLPWPRLSVPLDQVVTARTRSVNPLGEFGGWGYRVT
                     PKRSGLIYRSGEALVVRRTGDGREFAVTVDDAGTAAALLNTLAERRPETR"
     gene            13753..14118
                     /locus_tag="F0345_RS20310"
                     /old_locus_tag="F0345_20345"
     CDS             13753..14118
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893576.1"
                     /locus_tag="F0345_RS20310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20345"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_100454748.1"
                     /transl_table=11
                     /translation="MLFHIDPGSPVPLGDQVAAAARAAIASGGFAPGDRLPAARTLADS
                     LGVNVHTVLRGYQRLRDEGLIELRRGRGAVVSRTDSVTGRAALLPHARALVAEARSLGL
                     GENEVLALVRETLADPA"
     misc_feature    13756..13769
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.11"
                     /tool="antismash"
     gene            complement(14135..15199)
                     /locus_tag="F0345_RS20315"
                     /old_locus_tag="F0345_20350"
     CDS             complement(14135..15199)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552841.1"
                     /locus_tag="F0345_RS20315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20350"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_185393411.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 2.3e-11, bitscore:
                     41.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIMRIRGVVLPERVERTFWTDGEVLRTEPPAGRGAGREVETVVDG
                     GWLVPELVDVHTHPGAEEPEHGFDEAALRRHLEAHRDAGVLLVRTPGTMRRMPGWVDTE
                     PGLPRVRSAGRWLAAPGRFFPGVGRDLREDRLPGAAVEEATAASGWCKIIGDWRWDEPA
                     VPLDVMTAAVDAVHAVGGRVAVHCQTAEGSRNAVLSGADSLEHGMHLDPGLLELMARQG
                     TAYIPTLGAFAESAEVWRGRERSAKRSAWLAGWEGMVANVRAAYEAGVTVLAGTDTFPC
                     GTVAAESRQLFDAGLPAGEAVGAASWTARKWLGLPGLADGAPADLVAYDRDPTAHPEVL
                     GRPARIVLRGRVVR"
     gene            complement(15338..15733)
                     /gene="sodN"
                     /locus_tag="F0345_RS20320"
                     /old_locus_tag="F0345_20355"
     CDS             complement(15338..15733)
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="F0345_RS20320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20355"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_100454754.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKMQAN
                     DDPQYQTRAIVIKEQRAELAKHHVSVLWSDYFKPPHFESYPQLHQLVNDTLKALSAAKN
                     SSDPASGQKALDLIAEIDRIFWETKKA"
     gene            15910..16380
                     /gene="sodX"
                     /locus_tag="F0345_RS20325"
                     /old_locus_tag="F0345_20360"
     CDS             15910..16380
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950799.1"
                     /locus_tag="F0345_RS20325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20360"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_337590234.1"
                     /transl_table=11
                     /translation="MAIRRGEAGAAGTARGWRGRGRFGMVEVDGPSMVPTLEHGDWLLV
                     RYGARVRPGDVVILRHPFQQDLLVVKRAVERREGGWWVLGDNAFAGGDSTVYGVVPRAM
                     VLARVAARLRPRPTGGHGREPVRGVRATLGWAYSAVRPVRSEVSLSRRLRAR"
     gene            complement(16317..16913)
                     /locus_tag="F0345_RS20330"
                     /old_locus_tag="F0345_20365"
     CDS             complement(16317..16913)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470753.1"
                     /locus_tag="F0345_RS20330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20365"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_100454756.1"
                     /transl_table=11
                     /translation="MELASYSDYALRLVNSEEPARGTDTLTSVDAVRALFGTSTQAARR
                     ATDADVTRFRAVRGRLRAVFEAAADGDERQAVHLLNALLLEFPVSPQVSGHGELDAEGR
                     PDWHMHLADHPSNATSGYAAIAAMGLAFHLTEFGADRLGLCEAAPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRRESDTSERTGRTAE"
     misc_feature    16906..16921
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     gene            17008..17820
                     /locus_tag="F0345_RS20335"
                     /old_locus_tag="F0345_20370"
     CDS             17008..17820
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893572.1"
                     /locus_tag="F0345_RS20335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20370"
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="WP_100454758.1"
                     /transl_table=11
                     /translation="MTDAETAPTGTADAAAVQTGATPGTDWAAWQISWDQQQEWYLPDR
                     EERFRVMLDMVEAAAGPEPRVLDLACGTGSITDRLLKRFPKAQSTGVDLDPALLTIAEG
                     TFAGDDRVTFVTADLKDPDWPALLPHDSYDAVLTATALHWLHTEPLAALYGQIAGIVRD
                     GGVFLNADHMPDPATPRINAAERELRHRRMEEAKAEGAVDWSTWWRLAAADPVLAGPTA
                     RRFEIYGEHAEGDTPPAEWHARTLREAGFTEARTVWQSPSDAMVLGLK"
     gene            complement(17916..18677)
                     /locus_tag="F0345_RS20340"
                     /old_locus_tag="F0345_20375"
     CDS             complement(17916..18677)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973712.1"
                     /locus_tag="F0345_RS20340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20375"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_100454761.1"
                     /transl_table=11
                     /translation="MTAMVKAEGVHKSFGQVEVLKGIDLEVATGEVFCLIGPSGSGKST
                     FLRCINHLEKINAGRLYVDGDLVGYRQKGDRLYELKDAEVALKRRDIGMVFQRFNLFPH
                     KTALENVMEAPVQVRGVAKAAARERAGQLLERVGLSDKAGNYPSQLSGGQQQRVAIARA
                     LAMDPKLMLFDEPTSALDPELVGEVLDVMRQLAEEGMTMIVVTHEMGFAREVGDSLVFM
                     DGGVVVEAGDPREVLTDPRHERTQSFLSKVL"
     gene            complement(18674..19621)
                     /locus_tag="F0345_RS20345"
                     /old_locus_tag="F0345_20380"
     CDS             complement(18674..19621)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415538.1"
                     /locus_tag="F0345_RS20345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20380"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_100454763.1"
                     /transl_table=11
                     /translation="MSADIHKKDPEATPPGPAPTQAAPIKAVPVRHYGRYVSALIALAA
                     LGSVVYAFSEGDINWAFIPDYFFNDRILSGVRETLVLTFLSMVIGVAGGVLLAVMRLSK
                     NPVVSSIAWFYIWFFRGTPVLVQLFVWFNLGFVFEYVNLGPFYKDEWSDFMTPFLTALL
                     GLGLNEAAYMAEICRAGLLSVDEGQTEAAHALGMSQGKTLRRIVLPQAMRVIVPPTGNE
                     VINMLKTTSLVAAVQYYELFKHAQDIGMTSGATVEALFLAATWYLILTSVLSVGQYYVE
                     RYYARGSLRQLPQTPWQKVRAHLTSLSSRSEVTR"
     gene            complement(19652..20605)
                     /locus_tag="F0345_RS20350"
                     /old_locus_tag="F0345_20385"
     CDS             complement(19652..20605)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415540.1"
                     /locus_tag="F0345_RS20350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20385"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_100454764.1"
                     /transl_table=11
                     /translation="MTASITRRPRPLRSRLAAAGAITAVGALLLTGCGDQTAGAEDSGE
                     KKETAAPLAGKLPKKYQDSGVVKVGSDIAYPPVEFKDKDGRTVGLDVDLAAALGEQLGV
                     ELKFENGTFDTLLGGLRSKRYDIAMSAMTDTKARQEGLDSETGKKVGQGVDFVDYFTAG
                     VSVYTNKGKDQGIKTWQDLCGKKIVVQRGTVSHDLAKAESKKCEKGEIKMETFDNDQQA
                     QTRLRSGGADAGSSDFPVAAYAVKTSGGGDHFELVGEQVEAAPYGIAISKSNPELRDAI
                     KAALDAIIENGEYQKIVEKWGVEDGAVTEAVVNGGK"
     misc_feature    20948..20968
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.7"
                     /tool="antismash"
ORIGIN
        1 gttccccggg ccggcggccg ggccggcggc cggtcggtcc ccgccgccgg tcgcgggggg
       61 actccaggtg ctgtgcgtct cctcaggcac cggttccccg tccctcacgc cggaccgggg
      121 cccgcgccgc gttgcttgtg caggctgatc gagacggtgt tgtcctcggc gaccgaggag
      181 tcgaccttgc ccgcgagcgc ggagagcacc gtccaggcga acgtgtcccg ctcgggggcc
      241 ttgccgtcgg tggtgggtgc cgacaccgtc acctccagtg agtcgtcgat cagccggaag
      301 acgcagccga ggactgagcc cggcacggcc tgctggagca gaatcgcgca cgcctcgtcg
      361 acggcgatgc gcaggtcctc gatctcgtcg agggtgaagt ccaaacgcgc cgcgaggccg
      421 gccgtggccg tccgcagcac cgacaggtag gcacccgctg ccggcagccg gacttccacg
      481 aagtcctggg tcccgggctc gcctgcgata ggggacaccc tcacctccaa ggtggtacaa
      541 gcactttcgg ggctccgggg aggagtcccc gggacgcgcc acgttccagc cgtgacgcta
      601 ccgcgccgtc gaggtccgtg tcccaggacc cccgcccctg tgcctcactc atagtaagca
      661 tacttatacg cagggtggct aggggtctgc ggagctcaat tggaaagtcc gggcgccggg
      721 ttgacgtacc cagcgctcag acgatcgaac cgtccgcgta gcaccagcgc cacgactcgc
      781 ccggctccgc gctgcgcatc accgggtggc cgctccgctc gaagtgggcc gtcgcgtgcc
      841 ggtgcggaga ggagtcgcag cacgccacgt ggccgcagtg caggcacttc cgcaactgga
      901 ccgggtgcgt cccggcctcc aggcactcct cgcaggtgtc cgccgacggg gcgggctcgg
      961 ggtgcggcag ctcggcgaca tgggcgcatt tgttcatgat gggcaggtta acgcggctcc
     1021 tgtgccttct gtcatggtgt gccgcccgcc gagggggaag gacgggacca cccgccatgg
     1081 acgtactgcc gctgctgctc ctggtcgcgg gcagcaccgc cgtcgccggg gcggcccggc
     1141 gtacgcccgt tcccgccccg ctgctcctgg tcaccgcggg gctgctcgtg tcgtacgtgc
     1201 ccggcgtccc gcactacacg ctcgacccgg agatcgtgct gcccatggtg ctgccgccgc
     1261 tgctctacac ggccgccatg gacagctcct acctggacct gcgcgcccag gtccggtccg
     1321 tcgccctgct ctcggtcggc tacacgctct tcgcgacgct cgccgtcggc tgggccgtcc
     1381 acctggtcgt gcccgacctg ccgctcaccg ccgccctggt cctcggcgcg gtcgtggcgc
     1441 cgccggacgc ggtcgccgcc accgccgtgg cccggcgggt cgggctgccc tcccggatca
     1501 ccacgatcct gcagggcgag tccctggtga acgacgccac cgccatcacc gcctaccggg
     1561 tcgcggtcgc cgcggccgtc ggcgagtccg ccgggccgct gcacgccggg gcggagttcc
     1621 tggtcgcctc gctcggcggc gtcgcggtcg gcctggtcct catggtgccg ctccactggc
     1681 tccgcaccca cctgcgcgag cccctgctcc agaacaccct ctcgctgctc atcccgttcg
     1741 ccgcctacgc cctcgccgag tacgcccatg cctccggggt gctcgccgtg gtggtcgtcg
     1801 ccctctacct cggccaccac tcctggcagg tcgacttcgc cacccggctc caggaggacg
     1861 ccgtctggaa gatggtcgcc ttcgtcctgg agtccgccgt cttcgccctg atcggactcc
     1921 aactgccact cgtcgtcgga gggctgggcg aataccacgc gggccaggtc ctctggtacg
     1981 ccctcgccgt cttcctgctg gtcgtcgcca cccggttcgt ctggacctac ccggccgtcc
     2041 acctgccccg gctgctgtcc cgccgcgtcc gcgcccgcga gcccgacccc acctggaagg
     2101 gtcccttcgt cgtcgcctgg gccgggatgc gcggcgtcgt ctcgctcgcc gtcgccttct
     2161 ccatcccgca cggcgtccac gagggcggct cgttcccgta ccggaacctg atcctcttcc
     2221 tgaccttcac caccgtcatc ggcaccctgg tcgtgcaggg cctgaccctg cccgccctca
     2281 tccggctgct gcgcctgccc ggccgcgacg cgcgcgccga gacgctgctg gaggcgcagg
     2341 cgcagaacgc ggcgtccgag gcggccgaac accggctcga cgctctgctc accgacccgc
     2401 gcaacgccct gccggagccg ctcgccgacc ggctgcgggc cgtgctggag cgccgccgca
     2461 acgccgtctg ggaacgcctc ggtacggtca atccggagac gggcgagagc gtcgacgaca
     2521 cctaccggcg gctggcccgt accgtgatcg cctccgaacg ggaggtcttc gtcgccctgc
     2581 gcgaccagcg ccacatcgac gacgagatgc tccgcgacct gctgcgccgc ctcgatctgg
     2641 aggaggcggc ggcctaccgg gaggacgagt gagccgcggc cgcgctacgc ccgcgggaag
     2701 ggcggcccgg tgaccaccgc ggccaccgcc gtgccccggc ggaagcggcc gtccgccgcc
     2761 agcgcggcca ggccgtgcag cagcttggcg acgtaggcgc gttccacggg caggccgtgg
     2821 cgctgctcga acgcggtggc gaagcgctcc agctccgggc tgctgcgggc gtaaccgccg
     2881 tggtggaagc cgtcctcgac gctccaccgg ccacgctgcc cgccgaacgc cgcccgctgg
     2941 tgcgccgcca cctcggcccc gaggaagccg cccttcagca cggccacgcc caccgcccgc
     3001 tgctcgggcg cgagccccgc cgccagcccg gccagggtgc cgccggtgcc gcaggcgacc
     3061 cccgccaccg gcgcgtcctc ccgcagcgcg gccagttccc cgccgagcac ggcgcacgcc
     3121 cggaccgcgg cggcgtccga accgccctcg ggcaccacgc gcaccgcctg tcccgccccg
     3181 gcggcctcgg ccaccagttc gtcccggacc gccgggtcgt ccttccgccg gtaccgggcg
     3241 cggctgacga aggccagcct catgccgtcg gcgcggcagc gcgcgaggga ggcgttgagc
     3301 ggacggccgg ccagttcctc cccccggacg acgccgacgg tggggaagcc gaggagccgt
     3361 ccggccgccg ccgtcgcccg caggtggttg gaccacgccc cgccgaacgt caccaccgtc
     3421 cggccgtcgg ccgtgtcgag gacgggcgcg agtttgcgcc acttgttccc cgggatgtcc
     3481 ggatggatga ggtcgtcccg cttcagcagc agccggaccc cgtaccgctc gaaggccggt
     3541 tcgcgcagtt cccgcaccgg agaggggagc aggggccgcg ccggctcgtg ccccgggcgc
     3601 ccgtcgcggg cacggggctc ggacgccccg ggggacggcg gtacgggatc tcggcggatg
     3661 ctcacccctc cattgtcggc cccgccggta cgggcctcac ttgaggcggc cccggatgcg
     3721 ttcgcgcatc gaggccatgg tgaaaccgcg cgggtccacc ttgcccggct gccactccag
     3781 gtggccgatg acggaccgct cgttccagcc gtgcacccgg cagacggcgg ccgagacccg
     3841 ctcgatcgcg tcgagctggg cgctgggcca cgggtccttt ccgtcgccca ggttctcgca
     3901 ctcgaagccg taaaagcggg cgttcccgtc ggtgttggcc tcgttgaccg gggggtagcc
     3961 ggcgcgttcg gcgatgaccg ccgccaggac gtcgtcgtcg cccagcccgg cgtggttggc
     4021 acggccgtag ccgaccaggt ggacgcggcc gtccttggtg atgacgccgt ggcagagggg
     4081 gccggggagc gaggcgtggc ccttccggca gatctcgacc gtgcggtcgc tgccggaggt
     4141 gacggtgtga tggatcatca cgccgttcac cggtccccag gcgcccttgc tgttgcggtt
     4201 gtggctgcgc cagctgccca cctcgacgac ggtgaccccc tcgtccttga gggccttgag
     4261 gaatctgtcc gctgacatgg gtggggccat gccgcctcct tcgggtgcga agcggcgccc
     4321 ggccggtgcg cgggcacctc gtgtggatcg ctttgtaccc gcaatcacgg cccgtcaaga
     4381 ccgcgaaagg tccgcgggac gggtgtacga cgcgatccgg ccagccggag ggccgggcgg
     4441 ccggtcccct tgaaggcacg cgggcggggc ggcgccccgc cccgcccctt cgtcagcgca
     4501 ggccctgctc cccgtgggtg gcgatgtgct gctccagggc gcgcagggcg tcctgggtgg
     4561 cgcgcgggtc gccgccccgc cgctgctcgg cgtagtacgc ggagcccagc ttcttcagca
     4621 ggtcggcgcc ggcccgctgc acctgcacct cgtcgagctt ctgcttgccc tgggcgaggc
     4681 cgcgctgggc ctgctccttg gcgcggtcga ggaatccagc catggtccgt actccttctg
     4741 tcctgggcgc cccgaacccg gggccccggt gccggcgagg cgcggggccg ccgcccggcc
     4801 tgagggccgg acgcggcttc cgtccggctc aacggcccgc gcgcacgggt ggttcccggt
     4861 ggttcgcccg gcgtgtccgg tggcggggaa gggagttcag gcggccggct gggccgaggc
     4921 cagccacagg tccggcccga agacctcgta gtggatgtcg gcggggcgca ctccctgctc
     4981 caggagctgc tcgcggaccg accgcatgaa cggcagcggg ccgcagaggt aggcgcgggt
     5041 gccgggggcc accgggacgg ccttgaggtc gacgcggccg gtgagcgcgc cgggcccggc
     5101 ggtgtgttcc tcgtaccaga agtgggcctc ggcgtcggcg aggcggccgg tcagctcggt
     5161 gtgcggggcg cgcagcgggt gggtggcggg ggtgcggtcg ccgtgcacga cggtgacagg
     5221 gcccgcgtag gcgctgtcgg ccagttcgcg gagcatggcg acgaccgggg tgcagccgat
     5281 gccggcggag gcgagcagga gcggggccgg acggccgtcc gcgccggggg tgcggtcgag
     5341 gaccaggtcg ccgtagggcg cggagaggtc caggacgtca ccgacgcggg tgcgggcgtg
     5401 caggtggccg gagacctcgc cctccgggcc cggcccgccg gacacacgct tgacggcgat
     5461 ggtccgctcg tcgccctcgg gggcgccggt gagcgagtac tgtcggatct gccgcgcgcc
     5521 gtcgggcaac tcggcctgta cggagacgta ctgcccggcc cgataggggg cggccgggcg
     5581 gccgtcggcg gggcgcagcc gcaggacggc gacctccgcg gtgtcgtcgt ggcgtgccac
     5641 gacctcccag gggcgccagg tcccgccggc caggacgttc tgctcggcca tgaggcgttc
     5701 ctcgtgcgtg gccagggcgt tggccatcag ccagtacacc tcgtcccagg cctcggcgac
     5761 ctccggggtg gcggcctcgc cgagcacgtc cgcgatggcg gcgaagaggt gccggtggac
     5821 cagggcgtac tggtcgcggg tgacgccgag tgaggcgtgc ttgtgggcga tccgggcgag
     5881 catggcgtcg gggcggctgt ccggctggtc gagcaggtgg ccggcgaagg cggctatgga
     5941 cccggcgaga gcctgccgct gggtgcccgc ggcctggttg ccgcggttga acaggtcccg
     6001 cagcagttcg gggcggtcgg cgaagagccg gtcgtagaac tgcccggtga tctcgccgat
     6061 cgccgcgccg acggcgggca gggtggcgcg gacagtggcg gccgatcgct cggtgagcat
     6121 gaggactcct tcgggtggag cgaggtggag aaggtgactg gtggtgactg gcgagggcgt
     6181 cttaattggt atgtgggact ccaatttgac gccgtgcgcg gggcagggtc ggtcctgccg
     6241 ggcggggtga ggggtctacg ggcgcccggc gcggtgcggc gggtgtcgcg ggggagcgtc
     6301 aggtgtcgtc cggtgaccgg ctccgggcga tgtccagcag gacggggccg gccggggcgg
     6361 ccgcgaggcc gcccacggtc aacgggtcga gggtggcgaa gaaggactcc tgtgcctggc
     6421 ggagggctcc gcgcaggcgg caggcggaga gcagggggca cggctccgcg ccctcgcact
     6481 ccacgacgtc cccgacgccc tccagttcgc gcaccagggt gccgacggag gctgaccgcc
     6541 cggcctcggt gagggcgagc ccgccgcctc ggccccggcg cgcctcgatg aggccgaggc
     6601 gctggaggcg cgcgaccgcc ttggcggtgt gggtgtacgg aacgcgcata ccggcggcca
     6661 cctcccgggt ggtggggagg tcgtcggtgg ccttcgggtc ctcgacggcg agccgcatga
     6721 ggacgcgcag ggccagatcg gtgaagcgcg tgagccgcat ggccacagcc tagaaaactt
     6781 gcatatgtga tgcaacttaa ggctcctgta ggggaatgtt cgaaaagaaa cagcaagctc
     6841 ccccgccggg gagtcgatca ttcccactcg tttgtgtaat ggcgccgccg ctctgcgtga
     6901 tggaagtctg atcgtcgagt tcagtgcttg atcgggagga caattttcat gtcggtaggc
     6961 gaagagatcc gcgcggagca ggccacaccc cagcagagtc tggccacctc cgccgcgcgg
     7021 aacctggcca ccaccaccaa atccgtgccg cagatgcagg agatcagctc gcgctggctg
     7081 ctgcgcacgc tgccctgggt ggacgtgcag ggcggtacgt accgggtcaa ccgcaggctc
     7141 agctactcgg tcggtgacgg ccgggtcacc ttcgtgaaga ccggggaccg cgtccaggtc
     7201 atccccgccg agctgggcga actgcccgcg ctgcgggact tcgaggagca ggacgtcctc
     7261 accgagctgg cctcccgctg cgagcagcgc gaattcgagg ccggggagac gctcgcctcc
     7321 ttcggcagcc gtaccgacgc cgtcttcctc ctggcgcacg gccgcgtcga gaagatcggc
     7381 acgggccctt acggtgacga ctccgtcctc ggcgtcctcg ccgacggggc gtacttcggc
     7441 gagcaggccc tcaccgaccc ggaggccatc tgggagtaca cggcacgcgc cgccacccac
     7501 tgcaccgtcc tcgtcctgcc cggcgaccag gtcgcacagg tcgccgagcg tgccgagccg
     7561 ctcgccgccc acctgcggca gcttcgcagc ctgccgcaac agcggaccaa caagtacggc
     7621 gaagccccca tcgacctctc ggccggccac gtcggcgagg ccgtcctccc cggcacctac
     7681 gtcgactacg aggcctcgcc ccgcgagtac gagctgagcg tcgcccagac cgtcctgcgc
     7741 atccacagcc gcgtcgccga cctctacaac cagccgatga accagacgga gcaccagctc
     7801 cggctgaccg tcgaggcgct caaggagcgc caggagcacg agctgatcaa caaccgcgag
     7861 ttcggcctgc tcaacaactg cgagtacgac cagcggctcc agccgcacgc cggcgtgccc
     7921 ggccccgacg acatggacga actcctcagc cgccgccggg gatcgaagct cttcctcgcc
     7981 cacccgcgcg ccatcgccgc cttcggccgg gagtgcagca ggcgcgggat ctacccggag
     8041 tcggtggaga tcgccgggaa ccgcctgccg gcctggcgcg gcgtgccgat ctacccgtgc
     8101 aacaagatcc cggtcaccga ggcccgcacc agctccatcc tctgcatgcg tacgggcgag
     8161 gaggaccagg gcgtcatcgg cctgcggcag agcggcatcc ccgacgagat cgagcccagt
     8221 ctctcggtcc gcttcatggg catcagcgag caggcgatca tctcctacct ggtgacgacc
     8281 tactactcgg cggccgtcct cgtcccggac gccctcggtg tcctggagaa cgtcgagatc
     8341 ggccgctggc agtgagcggt cgctgatgaa ccgcacccac cacggtccac ccggccggcc
     8401 gtccgcccag ggcggcgggc ccggggcctc ggcaccaccc gccacccccg gcccgccggg
     8461 cggtgggatc agggccaccg tcctgcgggc cgggaggtgg gcgttcaccg ccccgctgcg
     8521 gctgctctgc accaccctca cccgcctcct gcccggctcc cgtgcgggcg ggggccggga
     8581 ggaggggggc gccgggggca tgtggcccgg ggacctgccc gctccccggg ggtcagctcc
     8641 ggagaagagc cgacgctccg cctcgccctc cgcgcggcgg agaccggccc cctcgccgta
     8701 ctgcgccatg ccgcacgtgc cccgcgtcgc ccgctgcccg caccggccgc cacccgctcc
     8761 gcgaaggctg ggccgcaggt gagaggagtc ggcccgtgcc ggacaggtcc ctgggggccg
     8821 gcactccggc ggggggtggc tgagccgagg gtggtgctgg gcggccgcgc gtgagccggg
     8881 ccgagggccc gacgcgcgtg gccgtcctgt cctgcggggg aaagcggtgc gggcggacgg
     8941 gggtgtactc acagtccggc acggcaccga cggcgcccgg cacgccctcc cgccgcaccg
     9001 gccaggccgg agtggctccg ctgccaagcc cttcgtccgg caggccgaga gcacgcaccg
     9061 gccacagcgg gcaccgcacg ggccttcgaa gacacgccct cgggcgagcg tgggagccgg
     9121 gcgcgcaggg cgcgtgccgt gcgcgggtga ggacggaccg gagtgtcctg gcagcctccg
     9181 tgcggacgaa gtgcggggag tgggtaaggg cgccggggat gccctcgggc cgggcgagcc
     9241 cgtacgccag tgcggggggt gaggaccggg cgaggggtgg agtggtgggc ggtttccgga
     9301 agtgcccgtg agacggaggc gggagtggtc cggggatcgg ggggcgcgga ccccggccgg
     9361 gatcgtccgg agagaacgat cacctgggga agacgatcgc cccggagaag atctcccggc
     9421 ggatcggcgg atcggcggat cggcggatcg gcggatcggt gcatcggtgg atcggcggat
     9481 cggcggatcg gtgcatcggt ggatcggtgg atcggtggat cggtggatcg gtggatcggt
     9541 gggaggggga ggagggcagg ctccccgtcg agaaacgggg gtcacgaccc gtgccggtgg
     9601 caggggcagg accggggcgc cggcggaggc cgggcgcgac gccgcgcggc tcctgccggg
     9661 agcgagggta gggcctgctc gaaggtgggt cgcggtggcc ggacgtaagg agcgctgttc
     9721 atgggcagga acgggacggc accggcccgg cctcggctcc gcgccccgag ccgggggacg
     9781 tgggggctgc cctcgattcc ggggcggacc gcgcggaccg tgccacggga cgctggggcg
     9841 tacggcaggg gagccccttg cggccgcccg gcccggggcc ggcgggggcg ggcggtgccg
     9901 gtggattccg gagcgggagg ggtgtgaggc ggtcgccggt gcggcgacct gggagcagca
     9961 ggggcagttc gacggcggga ccggggagaa gggaacaccg atgacgcaca ccacgcagag
    10021 cagaacccac agccacgagg ccgcggagat cctggacgag gcgagggcgg tggtcgggcc
    10081 cgaactgcgc cgggcggtcg acaccctgcc cgcgccgata cgccgcgtcg cccgctacca
    10141 cttcggctgg gaggacgagg cggggtccgc cgccggggcc aacggcggga aggcggtacg
    10201 gccggcgctg gtgctcgccg ccgtgcacgc tctgggcggg aggcccgagc gcgccctgcg
    10261 cagtgccgcc gccgtcgaac tcacccacaa cttcaccctc ctccacgacg acgtcatcga
    10321 ccgggaccgc acccgccgtc accgaccgac cgcctggacc gtcttcggcg acgccgacgc
    10381 gatcctcgcc ggggacgccc tccagtccct cgcccagcaa tggctggccg aggaccccca
    10441 cccacgagcc ggcgcggccg tcgcccgcct ggcccgctgc gtggtggagc tctgcgcggg
    10501 ccagcacacc gactgcgccc tggaggagcg cgcacccacc gaggtcgccc tcgacgagtg
    10561 cctcaccatg gcggagtcca agaccggcgc gctgctcggc tgcgcctgtg ccctcggcgc
    10621 gctccacgcc gacgccgggc cggagcagat cgccgccctc gacgccttcg gtcgcgaggc
    10681 cgggctcgcc ttccagctca tcgacgacat catcggcatc tggggcgacc ccgcgcgcac
    10741 cggcaagcct gccggcgcgg acctcacggc gcgcaagaaa tccctgcccg tcgtcgccgc
    10801 cctcacctcc ggcacagcgg ccggcgccga gttggcggaa cggtacgccg ggccgcccga
    10861 gccggacgaa ctggcccgca ccgtcgcgct ggtggaagcg gccggcgggc gggactgggc
    10921 gcaggcggag gcggccgacc ggatgggacg cgccgtgcag caactggcgc tggccgtccc
    10981 cgacccggcc cgggcgggcg ggctgctctc gctggcggag ttcgtcaccc gtcgctccca
    11041 ctgaggccgg gccgccctcc ccggaggcgt cctgatcccc acccgtcggg ctactggatg
    11101 ccctacgctg caacgggcct atgacggcag ggagttgaca gcgtctcccg ggccggggcc
    11161 gatccgtgac cgtggtgcgc gtaccggggt ggcagtgggc cgtccgggtg gcggccggac
    11221 cgcccggcgg gcgggggaga agggggcgac tgtgggagtg gcgacgcgta cggcgggggc
    11281 cgcggaccgg gaccgggtgg cggccctgct cgacaccgcc ttccaccacg acccggtgag
    11341 cagctgggtc ttccccgagg aggagcaccg ccgggccgtc cacggcgtct tcatggggtg
    11401 cttcctggac gcggcgctcg ccggggggcg cgtcgacctg ctggaggacg gctcggccgc
    11461 cgccctgtgg ctctcggtcc cggccgggga gcccgaggag gaggacgaca tgcccgccct
    11521 catgaggcgt accgccgacc cggacaacga gcgcgccgaa ctcgtcggcc gcctcaccgg
    11581 cgcgatccac cccaccggcc gcgcccacgc ctatctgctg ctggtcgccg tcgccccgga
    11641 ccggcagggc gagggcctgg gcaccgccct cctcaccccc gtcctcgaac agtgcgaccg
    11701 ggacggcctc cccgcctacc tggaggccag cagtgcccgc agccgggagc tctacctccg
    11761 cctcggcttc gccgaccgcg gcgagccgct ccggttgcct gaggggccgt tgatgtggcc
    11821 catgtggcgg gagcccgtga cgcactgagc ggcctcggcc cgtcccgccg ccccaccggc
    11881 tgacccgtcc gggagcggtc cgggccggcg ccggccggcg atggcgccgg aacctgtgac
    11941 gactccgccc gcgcgcaccc gtagccgcgg gccgcacccc cgcccgggct tcgtcgggcg
    12001 cggcgggccg cgccggctcg cacggaccgt cgacgccgtc cgaccggccc gggtggcggg
    12061 agcccgccag cggtggctga cccccgcctc ccgcaggccg gccggtccgc cggcttccgc
    12121 ggtcaccagt cccgggcgct gacgaggcgt tcggggtccg cgtccaggta gccgtgagcc
    12181 gtcgcgatga gccggaactc ctcggcgacc tcctcgtggg cggtggtctc gatctcgttg
    12241 ccggccgctt cggacccggt ctccagcgcg ttgaacgcct ttgtcgcggc gtcggtgagt
    12301 gcgtagaggg cgtggaggcc gggcggcctc tcgccccgat ccgctcgcgc ggggcggtga
    12361 ggatctcggc gcccttgtcc agggcccggt ccgggaacaa ggagtcgtcg tggagcgcgc
    12421 ggaggaatct ccgccgcgac ccgctgcccg tcgatcggta tgccgcccac cccgcctgaa
    12481 ccacgacgtc cccgctctcg ccccacggca ccgacacccc acggcactca catcccgcgg
    12541 ggctgacgct cccccggcgc tgatgcacca cggcacagac actccaccgc actgacgccc
    12601 cggcgcaccg gcgacgaggt ggctagggtc gcccctcctc gccgctcgcg ggttgttata
    12661 gttcaatgcg aacaagaggc ttggtctcca gcggtccccg gtgaggccgg gacgcgtgcc
    12721 cgagccggta cccctgccag cggaggagca gcccatgacc gccaccggcc gccgcgcccg
    12781 tgtcccccgt cggctcgtcg ccctcgtcgc cctgccgttc gtcgccgctt cggccctggc
    12841 ggcgggggtc caggccgcgg cgagcgaccg gctccccgcc cggctggccg tgcacttcgg
    12901 cgccggcggg gtgccggacc ggttcgagag cccggcgcag ttcctggtca ccgtggccgc
    12961 gttgctgctg ctcggtggtg cggcctggac cgtgctggtc gtgaggggag cccggggcgg
    13021 cggagccggt acgggcatgg cgaccgcgat ggggtggggg ctcgcggcct tcctgggctc
    13081 gatatccgtc ctgctgctcc agctcaacgc ggacgccgcc gacccggccg aggtccgcct
    13141 gcccctctgg cacttcggtg ccgccctcgc cgtggccctg accgccggct tcctcgggca
    13201 cgcgctggtc agggggctgg tccccgcctg gccgccggac cgggagtcct ccggcgccga
    13261 gcggctggac ctgccgcggc acgggcgcgc cgggtgggcg cggcgtaccg gttcgtggcc
    13321 gctgctgctg gccggcctgg tgaccctgtg cgtcgccgcc gccctgctgc tggtctccgg
    13381 cacgtcctgg tgggccggga tcgtactgct gctgagcggc ctcccgctcg tgctgatggc
    13441 ccaggccgac gtcaccgtcg accagcgcgg tctgaccgtg cgcctctcag gtctgccctg
    13501 gccccggctg agcgtccccc tcgaccaggt ggtcaccgcg cggacccggt cggtcaaccc
    13561 gttgggcgag ttcggcggct gggggtaccg ggtgacgccc aagcggtccg ggctgatcta
    13621 ccgttcgggg gaggcgctcg tggtgcgcag gaccggggac gggcgggagt tcgccgtcac
    13681 cgtggacgac gcgggcacgg ccgccgccct gctcaacacg ctggccgaac gccgcccgga
    13741 gacccgctga ccatgttgtt ccacatcgac cccggctccc cggtgccgct cggcgaccag
    13801 gtcgcggccg ccgcccgcgc cgccatcgcc tcgggcggct tcgcccccgg cgaccggctc
    13861 ccggccgccc gcaccctcgc cgactccctc ggtgtcaacg tccacaccgt gctccgcggc
    13921 taccagcggc tgcgcgacga ggggctgatc gaactccggc gcggacgggg cgccgtggtc
    13981 agccgcaccg actcggtcac cggccgcgcc gccctcctcc cgcacgcccg cgccctggtc
    14041 gccgaggccc gctcactggg gctcggcgag aacgaggtcc tggccctggt ccgcgagact
    14101 ctcgccgatc ctgcttgacg ggccgtcctg ccccctaccg caccaccctc ccccgcagca
    14161 cgatccgcgc gggccgcccc agcacctccg ggtgcgcggt cggatcgcgg tcgtacgcca
    14221 ccaggtcggc cggtgccccg tcggcgaggc cgggcaggcc cagccacttc cgggccgtcc
    14281 aggaggccgc accgaccgct tccccggcgg gcagcccggc gtcgaacaac tgccgggact
    14341 cggcggcgac ggtgccgcag gggaaggtgt ccgtcccggc gaggacggtg acgcccgcct
    14401 cgtacgcggc ccggacgttg gccaccatcc cctcccaccc ggccagccag gccgagcgct
    14461 tggcgctccg ctcccggccc cgccacacct ccgcactctc ggcgaaggcg cccagcgtcg
    14521 ggatgtacgc cgtgccctgg cgagccatca gctccagcag cccggggtcg aggtgcatgc
    14581 cgtgttcgag gctgtcggcc ccggagagga ccgcgttccg cgacccctcg gccgtctggc
    14641 agtgcacggc gacccggccg ccgaccgcgt gcacggcgtc gaccgccgcg gtcatcacgt
    14701 ccagcggcac ggccggttcg tcccaccgcc agtcgccgat gatcttgcac cagccggacg
    14761 ccgcggtggc ctcctccacg gcggcgcccg ggagtcggtc ctcccgcaga tcgcgcccca
    14821 ccccggggaa gaaccgcccc ggagccgcca gccaccgccc ggccgaccgg acccgcggca
    14881 gccccggctc cgtgtcgacc cagccgggca tccgccgcat cgtccccggc gtacgcacca
    14941 gcagcacccc ggcgtcgcgg tgtgcctcca gatgccgccg cagcgccgcc tcgtcgaaac
    15001 cgtgctccgg ctcctcggcc cccggatgcg tgtgcacgtc gaccagttcc gggaccagcc
    15061 agcccccgtc caccaccgtc tccacctcgc ggccggcccc gcgcccggcc ggcggctcag
    15121 tgcgcagcac ttccccgtcg gtccagaagg tccgctccac gcgctccggc aggacgacgc
    15181 cccgtatccg catgatcatg agcgggaccc tacgtctccg cgcgtgggcc gcgcgggaaa
    15241 aaccgcaccc ggcccgcgac ggacgccggg tgggcgtccc gcggaccggg tgcggtcggt
    15301 gggtggtccg gcccgtcacg ccgggccggt caccggatca agccttcttg gtctcccaga
    15361 agatgcggtc gatctcggcg atgaggtcca gggccttctg gccggaggcc gggtcggacg
    15421 agttcttggc ggccgagagg gccttcaagg tgtcgttgac cagctggtgc agctgcgggt
    15481 agctctcgaa gtgcggcggc ttgaagtagt cgctccacag gaccgagacg tggtgcttgg
    15541 ccagctcggc gcgctgctcc ttgatgacga tggcgcgcgt ctggtactgc gggtcgtcgt
    15601 tggcctgcat cttctcctgg acggccttga cggactccgc ctcgatgcgg gcctgggccg
    15661 ggtcgtacac gccgcagggc aggtcgcagt gggcgctgac cttcaccttg ggggcaaaca
    15721 ggcgggaaag catgaggtgc tgtccttcct cgtgatcgtc ttctcgcagg tgacactact
    15781 ccgtgagggg cgggttttct cggtcgcccc cgggggccta gggcgaaagg acggggtgag
    15841 agtgggaccg gggaggtgcc gccgggagtg tgggcgggta ggcgagtgag gcggacggaa
    15901 gggcgagaag tggcgatcag acgaggcgag gcgggggccg ccgggacggc gcgcgggtgg
    15961 cgcggccggg ggcggttcgg gatggtcgag gtggacggcc cgtccatggt gccgacgctg
    16021 gagcacggcg actggctcct ggtcaggtac ggcgctcgcg tccgcccggg tgacgtggtg
    16081 atcctgcgcc accccttcca gcaggacctg ctggtcgtca agcgcgccgt ggagcgacgt
    16141 gagggcggct ggtgggtgct gggggacaac gccttcgcgg gcggcgacag cacggtctac
    16201 ggggtggtgc cgcgcgccat ggtgctggcg cgggtggcgg cccggctgcg gccgcgcccc
    16261 accgggggtc acggacgtga gccggtgcgc ggggtgcggg cgacgctcgg ctgggcctac
    16321 tcggcggtcc gcccggtccg ctccgaggtg tcgctctcgc ggcgcttgcg ggcccggtag
    16381 gcggcgacgt tggcgcgggt cgcgcaccgg tccgagcagt agcgccggga gcggttggtg
    16441 gaggtgtcga ggtaggcgtt gcggcagggc gccgcctcgc agaggccgag ccggtccgcg
    16501 ccgaactcgg tgaggtggaa ggcgagcccc atcgcggcga tggcggcgta gccgctggtg
    16561 gcgttggagg ggtggtcggc caggtgcatg tgccagtccg ggcggccctc ggcgtcgagt
    16621 tcaccgtggc cggagacctg cgggctcacc gggaactcca gcagcagggc gttgagcagg
    16681 tgcaccgcct ggcgctcgtc gccgtcggcc gccgcctcga agaccgcgcg gagccggccg
    16741 cgcaccgcgc ggaagcgggt gacgtccgcg tcggtggccc ggcgggccgc ctgggtactc
    16801 gtaccgaaga gggcgcgtac cgcgtcgacg gaggtgaggg tgtcggtgcc ccgtgccggt
    16861 tcctcgctgt tgaccagacg cagggcgtaa tccgagtaag aggcgagttc cacttgtagt
    16921 ccttacgggc tcggtctagg gtcggtcggg caggcagatg taatggctag ctccgctttt
    16981 agggtattac gctacggagg agttcggatg acggacgcag agacggcgcc gaccggtacc
    17041 gccgacgcgg ctgcggtgca gaccggagcc accccgggga ccgactgggc cgcctggcag
    17101 atcagctggg accagcagca ggagtggtac ctccccgacc gcgaggagcg cttccgcgtc
    17161 atgctcgaca tggtcgaggc ggcggcgggc cccgaaccgc gcgtcctcga cctcgcctgc
    17221 ggcacgggaa gtatcacgga ccggctcctc aagaggttcc cgaaggcgca gagtaccggc
    17281 gtcgacctgg accccgcgct gctcaccatc gccgagggaa ccttcgccgg ggacgaccgg
    17341 gtcaccttcg tcaccgccga cctcaaggac cccgactggc ccgcgctgct cccgcacgac
    17401 agctacgacg cggtcctcac cgccaccgcc ctgcactggc tgcacaccga gccgctcgcc
    17461 gccctctacg gccagatcgc cggcatcgtc cgcgacggcg gcgtcttcct caacgccgac
    17521 cacatgcccg accccgccac cccgcggatc aacgccgccg aacgtgagct gcggcaccgc
    17581 cggatggagg aggccaaggc ggagggtgcc gtcgactggt ccacctggtg gcggctggcc
    17641 gccgccgacc cggtcctggc cgggccgacc gcccgccggt tcgagatcta cggggagcac
    17701 gccgaaggcg acacgccccc cgccgagtgg cacgcccgca ccctgcgcga ggccgggttc
    17761 accgaggccc gcacggtctg gcagtcgccg tcggacgcga tggtgctcgg gctgaagtaa
    17821 ccggggagcc ggtgcgcgac gccgcggggg cggtacggaa cacacgattc cgtaccgccc
    17881 ctgtacgcgt gccgggcctg acggcctcgc cgggctcaga gcaccttcga gaggaacgac
    17941 tgcgtccgct cgtgccgcgg gtcggtcagc acctcgcggg gatcgcccgc ctccacgacc
    18001 acgccgccgt ccatgaagac cagcgagtcg ccgacctccc gggcgaagcc catctcgtgg
    18061 gtgacgacga tcatcgtcat gccctcctcg gcgagctggc gcatcacgtc cagcacctca
    18121 ccgaccagct ccgggtcgag tgccgaggtc ggctcgtcga agagcatcag cttcgggtcc
    18181 atcgccagcg cgcgggcgat cgccacgcgc tgctgctggc cgccggagag ctgcgagggg
    18241 tagttgcccg ccttgtcgga gaggcccacc cgctccagga gctgcccggc ccgctcccgg
    18301 gccgccgcct tggcgacgcc ccggacctgg accggcgcct ccatcacgtt ctccagcgcc
    18361 gtcttgtgcg ggaagaggtt gaagcgctgg aagaccatgc cgatgtcccg gcgcttcagg
    18421 gcgacctcgg cgtccttcag ctcgtagagc ctgtcgccct tctgccggta gccgaccagg
    18481 tcgccgtcga cgtagagccg tccggcgttg atcttctcga ggtggttgat gcagcgcagg
    18541 aaggtcgact tccccgagcc ggaggggccg atgaggcaga acacctcgcc ggtggccacc
    18601 tccaggtcga tgcccttgag cacctcgacc tggccgaagg acttgtggac gccctcggcc
    18661 ttcaccatgg cggtcatcgg gtcacctccg agcggctgga gagcgaggtc aggtgcgcgc
    18721 gcaccttctg ccagggggtc tgcggcagct gccgcagcga gcctcgggcg tagtaccgct
    18781 cgacgtagta ctggccgacg ctgaggaccg aggtgaggat caggtaccag gtggcggcca
    18841 ggaagagcgc ctcgacggtg gcgccggagg tcatgccgat gtcctgcgcg tgtttgaaca
    18901 actcgtagta ctggacggcc gccaccaggg aggtcgtctt cagcatgttg atgacctcgt
    18961 tgccggtggg cggcacgatc acgcgcatcg cctgcggcag cacgatgcgg cgcagcgtct
    19021 tgccctggct catgccgagc gcgtgggccg cctcggtctg gccctcgtcg accgagagca
    19081 gaccggcccg gcagatctcc gccatgtacg cggcctcgtt gaggccgagg ccgagcaacg
    19141 ccgtcaggaa cggcgtcatg aagtccgacc actcgtcctt gtagaacggg ccgaggttca
    19201 cgtactcgaa gacgaagccg aggttgaacc agacgaagag ctgcaccagg accggggtgc
    19261 cccggaagaa ccagatgtag aaccaggcga tggaggagac caccgggttc ttcgacagcc
    19321 gcatcaccgc cagcagcaca ccgccggcca cgccgatgac catcgagagg aaggtcagga
    19381 ccagcgtctc gcggacaccg ctgagaatgc ggtcgttgaa gaagtagtcc gggatgaagg
    19441 cccagttgat gtcgccctcg gagaacgcgt acacgaccga gccgagcgcc gcgagcgcga
    19501 tcagcgccga gacgtagcgg ccgtagtggc ggaccgggac ggccttgatg ggagccgcct
    19561 gggtgggggc cggaccggga ggggtggcct ccgggtcctt cttgtggatg tcagcagaca
    19621 caggtgttgc ctttcagcga cgccggaggg gtcacttgcc gccgttgacg accgcctcgg
    19681 tgaccgcgcc gtcctcgacg ccccacttct cgacgatctt ctggtactcg ccgttctcga
    19741 tgatcgcgtc cagcgccgcc ttgatcgcgt cccgcagctc cgggttggac ttggagatgg
    19801 cgatgccgta cggcgccgcc tcgacctgct cgccgaccag ctcgaagtgg tcgccgccgc
    19861 ccgaggtctt caccgcgtac gcggcgaccg ggaagtcgga ggaaccggcg tcggcaccgc
    19921 ccgagcgcag ccgcgtctgg gcctgctggt cgttgtcgaa ggtctccatc ttgatctcgc
    19981 ccttctcgca cttcttcgac tcggccttgg ccaggtcgtg cgagacggtg ccgcgctgga
    20041 cgacgatctt cttgccgcag aggtcctgcc aggtcttgat gccctggtcc ttgcccttgt
    20101 tggtgtagac ggagacgccg gcggtgaagt agtcgacgaa gtcgacgccc tggccgacct
    20161 tcttcccggt ctcggagtcc aggccctcct ggcgcgcctt ggtgtcggtc atcgccgaca
    20221 tcgcgatgtc gtaccgcttg gagcgcaggc cgccgaggag cgtgtcgaag gtgccgttct
    20281 cgaacttcag ctccactccg agctgctccc cgagcgcggc ggcgaggtcc acgtccagac
    20341 cgacggtcct gccgtccttg tccttgaact ccaccggcgg gtacgcgatg tccgagccga
    20401 ccttgacgac gccgctgtcc tggtacttct tcgggagctt gccggcgagc ggggcggccg
    20461 tctccttctt ctcgccggag tcctcggcgc ccgcggtctg gtcgccgcag ccggtgagca
    20521 ggagggcgcc cacggccgtg atcgcgccgg ccgcggcgag acgggagcga aggggccggg
    20581 ggcgacgcgt gatgctggcg gtcatgaggg attcctccga caggtgagcg gatggcgagg
    20641 gtggccgacg ggtcgttggc acacaccttc gggtgtcgcg acctcgtgcg atgggtggca
    20701 tcttgccatt cggaccgagg ggagcgaggt gccgcccatg tcaaaatcgg ataacgggtc
    20761 cacccgctgc cccaacagcc ctgtgttccc cgggcatccg tcatgcctgc ccgggtcgtt
    20821 accttgctca cgcgcatacc gcgcatctcg ccatgtggga cagagaagtg gcgtcggggg
    20881 aggttcccgt gaagtcggac atgtgagcgg acggtgtggc cgattcggct cggcacgcgc
    20941 caccgcgatc aggtagaaaa gacggttaca cccctcatcc ggggctcagg acgcgtgtgc
    21001 ggcgcgtccg cgcgtgcgac ctcccccgtg tggaggcggg ccca
//
