LOCUS       NZ_CP045704            20975 bp    DNA     linear   CON 03-SEP-2024
DEFINITION  Streptomyces rutgersensis strain NBH77 chromosome, complete genome.
ACCESSION   NZ_CP045704
VERSION     NZ_CP045704.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces rutgersensis
  ORGANISM  Streptomyces rutgersensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces diastaticus group.
REFERENCE   1  (bases 1 to 6848830)
  AUTHORS   Benaud,N., Edwards,R.J., Amos,T.G., D'Agostino,P.M.,
            Gutierrez-Chavez,C., Montgomery,K., Nicetic,I. and Ferrari,B.C.
  TITLE     Antarctic desert soil bacteria exhibit high novel natural product
            potential, evaluated through long-read genome sequencing and
            comparative genomics
  JOURNAL   Environ Microbiol 23 (7), 3646-3664 (2021)
   PUBMED   33140504
REFERENCE   2  (bases 1 to 6848830)
  AUTHORS   Benaud,N., Edwards,R.J. and Ferrari,B.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2019) School of Biotechnology and Biomolecular
            Sciences, University of New South Wales, Botany St, Sydney, NSW
            2052, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-DEC-2018
            Assembly Method                   :: FALCON v. v 1.8.6
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014216335.1-RS_2024_09_03
            Annotation Date                   :: 09/03/2024 04:34:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,921
            CDSs (total)                      :: 5,831
            Genes (coding)                    :: 5,642
            CDSs (with protein)               :: 5,642
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 189
            CDSs (without protein)            :: 189
            Pseudo Genes (ambiguous residues) :: 0 of 189
            Pseudo Genes (frameshifted)       :: 102 of 189
            Pseudo Genes (incomplete)         :: 130 of 189
            Pseudo Genes (internal stop)      :: 14 of 189
            Pseudo Genes (multiple problems)  :: 50 of 189
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:08:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4779533
            Orig. end                         :: 4800508
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045704.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Belinda Ferrari, QAP Lab
            4002, Bioscience South E26, UNSW Sydney, Australia 2052 (Quarantine
            regulated isolate).
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20975
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="12"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20975
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20975
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10975](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10975
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(345..1703)
                     /gene="aroA"
                     /locus_tag="F0345_RS20110"
                     /old_locus_tag="F0345_20145"
     CDS             complement(345..1703)
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642411.1"
                     /locus_tag="F0345_RS20110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20145"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_100454663.1"
                     /transl_table=11
                     /translation="MTLNPVSTPLWPAPYATGAVEATVQVPGSKSVTNRALVLAALAAE
                     PGWLRRPLRSRDTVLMADALRTLGVGIEETVSSDSAAPGSAVPRGGGGEAWRIIPSGLR
                     GPATVDVGNAGTVMRFLPPLATLADGDIRFDGDPRSYERPLHGVIDALRALGARIDDDD
                     RGSLPLTVHGTGSLDGGTVEIDASSSSQFVSALLLSAPRFNQGVEVRHIGPRLPSMPHI
                     RMTVDMLRRVGAQVDEPESGGEPNVWRVTPGALLGRDLTVEPDLSNAQPFLAAALVTGG
                     RVVIPDWPARTTQPGDRLREIFTTMGGSCELTEAGLVFTGSGRVHGIDVDLGEVGELTP
                     GIAAVAALADGESVLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLRIRPRPLHG
                     GVFRTYDDHRMATAGAVLGLAVKDVEIENVATTAKTLPDFPDLWTAMLDGSGQ"
     misc_feature    1682..1696
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.13"
                     /tool="antismash"
     gene            complement(1794..2519)
                     /locus_tag="F0345_RS20115"
                     /old_locus_tag="F0345_20150"
     CDS             complement(1794..2519)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950755.1"
                     /locus_tag="F0345_RS20115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20150"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_100454666.1"
                     /transl_table=11
                     /translation="MQSTTTAPAADLWDRVTGTQTAPEFWLVVATGVAALAVVLWGPAW
                     RPARNAVTIAHEGGHGLVALVTGRKLEGIRLHSDTSGLTVSRGRPTGPGMILTALAGYT
                     APSLLGLGGAWLLAAGHITALLWAATALLLALLVMVRNAYGVLTVLITGGLFVAVSWLA
                     DSQVQAVFAYAAVWFLLLGGVRPVFELQSKRRRGGAPDSDADQLARLTHAPAAVWLFFF
                     HAVALCSLIGGGGRLLGRS"
     gene            2610..3473
                     /locus_tag="F0345_RS20120"
                     /old_locus_tag="F0345_20155"
     CDS             2610..3473
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="F0345_RS20120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20155"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_100454669.1"
                     /transl_table=11
                     /translation="MCGRYAATRSPEDLSEIFGVEKAELSEAAADGQETGEAPSPSETL
                     VPDWNVAPTKEVPAILDRPVKGSDDPRPVRQLRTLTWGLVPSWAKSPDGGARMINARAE
                     TVHEKPAYRRAFAARRCILPADGYYEWVTAPEERKLEEEGKRKRPRKQPYFVTPADGSV
                     FAMAGLYEFWRDPSLPGDHPRAWWVTCSVITTEAETAPLAVGPEEGPRALADIHPRMPL
                     MLPPDRWDAWLDPSRTDVAELRELLAAPPEGLMRAYPVATAVSNVRNNGPGLVTELEGP
                     EVGTLF"
     gene            3994..4542
                     /locus_tag="F0345_RS29310"
     CDS             3994..4542
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013427.5"
                     /locus_tag="F0345_RS29310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="WP_258057207.1"
                     /transl_table=11
                     /translation="MARARKQAGAAEEAALRLGDDCELDVGDAGSRRTAVEEERRRADE
                     ARSAVQRAEAALRRLDEGAFGRCVSCGAAVGPERLAALPHTELCAPCSGAGGRGLPRGA
                     AQQDPTGARSRRGRSGRTVEGEARRAPEPGGTSMSDTTPGQAEGERDEEEPGREAREQP
                     ARTTPSQAEGDRDDEAEDG"
     gene            4591..5454
                     /locus_tag="F0345_RS20130"
                     /old_locus_tag="F0345_20165"
     CDS             4591..5454
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016467393.1"
                     /locus_tag="F0345_RS20130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20165"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_100454674.1"
                     /transl_table=11
                     /translation="MTGHPQDRGPARITFIGNATLLIEYGPLTLLTDPNFLHRGERAYL
                     GNGLSSARLLDPALELSELPGLDAVVLSHLHGDHWDRRARRGLAKDLPILTTPHASRRL
                     QGLHGFSRAVGLPTWQSETLVREGRQVRVTALPGRHGPALAHRLLPPVMGSLWEFGAAG
                     AEPEVRLYVTGDTVMFPGVHEIARRCPDVQLAVLHLGGTTLPGGLLVTMDARQGVEMMR
                     ALELPEVLPVHYEEYGVMRSPLADFLAATEREGLGDRVVRCRRGERVAVGPNGAVAIGG
                     PLRGER"
     gene            5569..6255
                     /locus_tag="F0345_RS20135"
                     /old_locus_tag="F0345_20170"
     CDS             5569..6255
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016469652.1"
                     /locus_tag="F0345_RS20135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20170"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_371874298.1"
                     /transl_table=11
                     /translation="MNAPTPETDVTSAPLPSGEAVTVPTPGGDARVTWFRARRPRAVLA
                     LGHGAGGGIEARDLVALARALPGHGVSVALVEQPWRVAGRKVAPAPKTLDVAWRAVWPK
                     LAAQGLPVVAGGRSAGARVACRTGAGLGACGVLALSFPLHPPGRPERSRAEELLGTGLP
                     TLVVQGGRDPFGRPEEFPAGSHDLAEVPHGDHGFAVPRKAPVTGEETLAVITEAVGEWL
                     ERLPLA"
     gene            6525..7202
                     /locus_tag="F0345_RS20140"
                     /old_locus_tag="F0345_20175"
     CDS             6525..7202
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="F0345_RS20140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20175"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_189400099.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGSKDDVPEKPEETSAERTARFERDALAFLDQMYSAA
                     LRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRKKQREPQR
                     SAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKSALQAIPEEFRIAVYLADVE
                     GFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGSGASAAEPNDRKG
                     AGS"
     gene            7199..7507
                     /gene="rsrA"
                     /locus_tag="F0345_RS20145"
                     /old_locus_tag="F0345_20180"
     CDS             7199..7507
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642406.1"
                     /locus_tag="F0345_RS20145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20180"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_185393405.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEVLDHLYEFLDHEMPDSDSNKIRTHFDECSPCL
                     EKYGLEQAVKKLVKRCCGQDDVPADLRDKVISRLDMIRAGQTVPQHDIVSTEAADSS"
     gene            7812..8804
                     /locus_tag="F0345_RS20150"
                     /old_locus_tag="F0345_20185"
     CDS             7812..8804
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415712.1"
                     /locus_tag="F0345_RS20150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20185"
                     /product="hypothetical protein"
                     /protein_id="WP_100454682.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARTAGLRAVALLDRDTGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLKIPGEAAASGEPSGMGLGSAAVRISPEGEAEVVWGRRLDPARIEVQSIPL
                     PSSGRRWGEVILHDGVPHGERTTASGDTYPVFDEIELWAPSPVPTWVVLLEAQEPADRD
                     ALELLAADAGFAAEDWSSSVRLLCRTCSESRMPSDEGGGERHVDPHDHSEPGQPGPLGH
                     RDTGGEGDLWVPERECGIAAPPALVRGLLDGWVADSPDSRSWRDLEEVC"
     gene            8923..9579
                     /gene="def"
                     /locus_tag="F0345_RS20155"
                     /old_locus_tag="F0345_20190"
     CDS             8923..9579
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="F0345_RS20155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20190"
                     /product="peptide deformylase"
                     /protein_id="WP_100454685.1"
                     /transl_table=11
                     /translation="MAQQDTEQQAVAGGVLPVDDEGFVIDTEDTEEREAAYRARGTARP
                     ITVVGNPVLHRETKDVTVFDAELAELVDDMFASQRAAEGVGLAANQIGVDKKVFVYDCP
                     DDEGVRHVGVVCNPVLDELPAERRVLDDSNEGCLSVPTAYAELARPDHAVVRGQDEKGN
                     PIVVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKEALRQMAEGTPRYETVPND"
     misc_feature    9705..9719
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.07"
                     /tool="antismash"
     misc_feature    9952..9965
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.14"
                     /tool="antismash"
     misc_feature    complement(9952..9965)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.17"
                     /tool="antismash"
     gene            10001..10975
                     /locus_tag="F0345_RS20160"
                     /old_locus_tag="F0345_20195"
     CDS             10001..10975
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470738.1"
                     /locus_tag="F0345_RS20160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20195"
                     /product="multidrug MFS transporter"
                     /protein_id="WP_100454688.1"
                     /sec_met_domain="T1TS (E-value: 8.3e-51, bitscore: 172.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESRAWLLEKRLMPADKVTRYADELRYTDLIAGYYVGAPREVISA
                     ISDFSTWFFVWDDQHDRDAVHGRRDSWYRLSADLHTALDAPGDHLAHPEPLVAAFAETV
                     HRLGGFLSADWNRRFARNFHAIVGAYDQEFENRVTKVTPSVADYIELRRHTFGHSVWID
                     LLEPTAGREIPESLRTSGPFMAAARHCQDFSAWYNDLCSLPKELAGDDQHNLGISLIRH
                     EGLSLEEAVTEVRKRVENCVTEFEVAEKELRELLDGHLAALPGAAASEEARSVAEAVGS
                     AVFNMRNWFSSVYWFHHESGRYRVDSWDDRSTPPYVSDLAGDA"
     misc_feature    complement(10023..10032)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.67"
                     /tool="antismash"
     gene            10972..12339
                     /locus_tag="F0345_RS20165"
                     /old_locus_tag="F0345_20200"
     CDS             10972..12339
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018535174.1"
                     /locus_tag="F0345_RS20165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20200"
                     /product="cytochrome P450"
                     /protein_id="WP_115068011.1"
                     /sec_met_domain="p450 (E-value: 4.6e-78, bitscore: 261.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTEPVIERPAAPGPRTAPLVAGSVPVLGHAPSLVRDPLAFLTGL
                     RDHGDLVRVKLGPKTAYAVCAPELVGALLRNSQEFVVGGPLWENLEVLLGKGVATSNGA
                     DHRRQRRMMQPAFRPERIASYATVMEEESRAMADRWRDGQVVDIGAETFSCAVRVVARS
                     LLEVDSIGAKADRISSSLHTVFSGLYRRMILSFGPLHRLPTPANRRFERALADLHQLVD
                     EVIAERHAEGKGPDDLLDILLTAEDGEGRPLSDQEIHDHLVSLIVAGAENVASTLAWCF
                     QLLTEHPAEEQRVAEEALSVAPGRPVDFGDLGSLEHTRNAIVESMRIRPAAWIFTRRAV
                     ADTELGGYRIPAGADIIYSAYAMQHDPRSFDRPDVFDPDRWIPERAEKVPQYAMMPFST
                     GNRKCPGDHFSMVEATLMLATVVPRWRLVPVPETDPAPRIGITLQPKRAVFRVERR"
     gene            complement(12424..13476)
                     /locus_tag="F0345_RS20170"
                     /old_locus_tag="F0345_20205"
     CDS             complement(12424..13476)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992855.1"
                     /locus_tag="F0345_RS20170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20205"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_185393406.1"
                     /transl_table=11
                     /translation="MTTPDTTPAANAHTVGTAKNLLDPGFELTLRPMRYPDFYERYRDA
                     IKNTWTVEEVNLHSDVADLAKLSPGEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSP
                     EARLYLSRQLFEEAVHVQFYLTLLDTYLPDPADRADAFAAVENIPSIREKAEFCFRWMD
                     SVDKLDQLESQADRRKFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWV
                     FRDETMHMSFAFDVVDTVRKEEPELFDDRLQEQVVAMLKEAVEAELQFARDLCGEGLPG
                     MNTESMREYLECVADQRLTRLGFAPVYGSQNPFSFMELQGVQELTNFFERRVSAYQVAV
                     EGTVSFDDDF"
     gene            complement(13476..15845)
                     /locus_tag="F0345_RS20175"
                     /old_locus_tag="F0345_20210"
     CDS             complement(13476..15845)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966408.1"
                     /locus_tag="F0345_RS20175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20210"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_185393407.1"
                     /transl_table=11
                     /translation="MTIAPADPSTAEVRAEEIQGPGGALLRTLTDLTADLPDTDPGRVA
                     AAALRGRNAASDEAELRSLATEAAAGLISEDPAYSRLAARLLARTIAEEAAGQGVTAFT
                     ESVATGHREGLIADRTAAFVTAHAERLDALVDPAADDRFGYFGLRTVHSRYLLRHPHTR
                     QVIETPQHFMLRVACGLAADESVQALDEVASLYRLMSALSYLPSSPTLFNSGTRHPQMS
                     SCYLLDSPKDELESIYDRYHQVARLSKHAGGIGLAYSRIRARGSLIRGTNGHSNGIVPF
                     LNTLDASVAAVNQGGRRKGAAAVYLETWHADIEEFLELRDNTGEDARRTHNLNLAHWIP
                     DEFMRRVDADADWSLFSPSDVPELTDLWGAAFDAAYRAAEAAGLAKRTIPARELYGRMM
                     RTLAQTGNGWMTFKDTSNRTANQTALPGHTVHSSNLCTEILEVTDDGETAVCNLGSVNL
                     GAFVTGGALDWERLDEAVRTAVVFLDRVVDINFYPTEQAERSNSRWRPVGLGAMGLQDV
                     LFQLRLPFDSPEARRLSTRIAERIMLTAYETSCELAERNGPLPNWDRTRTAQGVLHPDH
                     YDTDLAWPQRWEALRARVARSGMRNALLLAIAPTATIASIAGVYECIEPQVSNLFKRET
                     LSGEFLQVNSYLVEDLKRLGVWDARTREALREASGSVQGFAWVPEELRALYRTAWELPQ
                     RGLIDMAAARTPFLDQSQSLNLFMETPTIGKLSSMYAYAWKKGLKTTYYLRSRPATRIA
                     RAAGGSAPATVPAQAAPEADAVACSLENPESCEACQ"
     regulatory      complement(16006..16082)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(16097..16110)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     misc_feature    complement(16104..16118)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(16135..16149)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 23.01"
                     /tool="antismash"
     gene            complement(16707..16949)
                     /locus_tag="F0345_RS20180"
                     /old_locus_tag="F0345_20215"
     CDS             complement(16707..16949)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642403.1"
                     /locus_tag="F0345_RS20180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20215"
                     /product="YbdD/YjiX family protein"
                     /protein_id="WP_100454699.1"
                     /transl_table=11
                     /translation="MSGEAAHRPGRLGVLAHRLRAGARWIGWYVREVSGETAYEKYAAH
                     LRRHDPDAEVMTRRQFERSRMDAREADPRDGFRCC"
     gene            complement(16946..19156)
                     /locus_tag="F0345_RS20185"
                     /old_locus_tag="F0345_20220"
     CDS             complement(16946..19156)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009267 - cellular response to starvation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1185: carbon
                     starvation protein A"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642402.1"
                     /locus_tag="F0345_RS20185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20220"
                     /product="carbon starvation CstA family protein"
                     /protein_id="WP_185393408.1"
                     /transl_table=11
                     /translation="MAEPAPPASGNRKLSAKSIAVWTLVAVVGAIAWSVLALSRGEEIS
                     AIWMLAAALGSYAIAYRFYARFIANKVLKVDKDRATPAERLDNGVDFQPTDRRVLFGHH
                     FAAIAGAGPLVGPILAAQMGYLPGTIWIVAGVIFAGAVQDMVTLFFSTRRNGRSLGQMA
                     RDEIGPVGGVAALIAVFMIMIILLAVLALVIVNALAGSPWGVFSIGMTIPIALFMGVYL
                     RTMRPGKVTEVSVLGVALLLLAIVGGGWVAESSMADFFTLEPGTLVIWMVVYGFFASVL
                     PVWMLLAPRDYLSTFMKVGTIVLMAVCVVIAMPTLKMDGVTSFATSGAGPVFSGSLFPF
                     VFITIACGALSGFHSLVSSGTTPKMVQKETQIRMIGYGAMLTESFVAIMAMIAACIIDP
                     GLYFAINSPAGVLGDTVNSASEAVANLGFTISPDQLAQAAKDVEEASLLSRTGGAPTFA
                     LGMAEIFASALGGAGMKAFWYHFAIMFEALFILTTVDAGTRVGRFMLQDTLGNVWKPMR
                     RVSWWPGVWLTSAVVVGCWGYFLWVGVHDPLGGINQLFPLFGIANQLLAAVALAVCTTL
                     LIKSGRLKWAWVTGVPLVWDVAVTLTASWQKVFSDNPAIGFFAQRAKYQDGIDAGEVLA
                     PAKSMSDMHTVVTNSTVDGVLSIVFAVLIIIVLVDAGRVSYNAIRRPESVKMAEAPFEQ
                     SKIVAPAGMFPTAEEKAELALVGAGAPVSADDAPAGQGGGKA"
     gene            complement(19669..20457)
                     /locus_tag="F0345_RS20190"
                     /old_locus_tag="F0345_20225"
     CDS             complement(19669..20457)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950769.1"
                     /locus_tag="F0345_RS20190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_20225"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_181843958.1"
                     /transl_table=11
                     /translation="MTTDAGGTRTRTAGGPATEPTSPVRATRVPKYYRLKRHLLDMTQT
                     LPPGTSVPPERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLT
                     SYTEDMRAQGLEPTSQLLEVGYITADDSLAALLDITAGSRVLRIERLRLASGEPMAIET
                     THLSAKRFPALRRSLVKYTSLYTALYEVYGVRPAEAEETIETSLATPREAALLATDVGL
                     PMLMLSRHSRDETGAPVEWVRSVYRGDRYKFLARLKRPVE"
     misc_feature    complement(20615..20630)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.28"
                     /tool="antismash"
     misc_feature    complement(20639..20654)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.29"
                     /tool="antismash"
ORIGIN
        1 cgtcgtcgtc ggccgtgcgg cgcagcaccg aggcgcgctc ctcgatccgc acgatgcgcg
       61 ccagggtgtc cttctctccg gagagatccc cgaccaccgc cacccggtcg cccaccaccg
      121 ccgccttgcg gcccagctcg cgggccttca tcgcggtcac cgtacggccc tcgaccaggc
      181 aggtgatccg gccccggtcc acggtgagga ccatgccctc ggcggcgtcc tcgtgcttgg
      241 ggcgggtgtg ggtgcggggg cggctgcccc ggcggctggg gcggacgcgg atgtcgtcct
      301 cgtcggggtt ctttccgtaa cggcgcatcg tcagctcccg gccgtcactg gccggacccg
      361 tcgagcatgg cggtccacaa gtcggggaag tcgggcaggg tcttcgcggt ggtggcgacg
      421 ttctcgatct cgacgtcctt caccgccagt cccaggaccg cgccggcggt cgccatccgg
      481 tggtcgtcgt aggtgcggaa gacaccgccg tgcagcggac ggggacggat gcgcaggccg
      541 tcggcggtct ccgtgacgtc gccgcccagc tcgttgatct ccttggtgag cgccgccagc
      601 cggtccgtct cgtgcagccg caggtgcgcc acgccgcgca ggacggactc gccgtcggcc
      661 agcgcagcga cggccgcgat ccccggggtc agctcgccga cctcaccgag gtccacgtcg
      721 atgccgtgga cgcggcccga gccggtgaag accaggccgg cctcggtgag ttcgcaggaa
      781 ccacccatcg tggtgaagat ctcccgcagg cggtcacccg gctgcgtggt gcgggccggc
      841 cagtccggga tcaccacgcg gccaccggtg accagcgccg ccgccaggaa cggctgggcg
      901 ttcgacaggt ccggctcgac ggtgaggtcc cggccgagca gcgcgcccgg ggtgacccgc
      961 cagacgttcg gctcgccgcc cgactcgggc tcgtcgacct gggcgccgac ccggcgcagc
     1021 atgtcgacgg tcatccggat gtgcggcatc gagggcagcc tggggccgat gtgacggacc
     1081 tccacgccct ggttgaaacg gggcgccgac agcagcaggg cgctgacgaa ctgggaggac
     1141 gaggaggcgt cgatctcgac cgtgccgccg tccagtgagc ccgtgccgtg caccgtcagc
     1201 ggcaggctgc cccggtcgtc gtcgtcgatc cgggcgccga gcgcgcgcag cgcgtcgatc
     1261 acgccgtgca gcggacgctc gtaggagcgc gggtcgccgt cgaagcggat gtcgccgtcg
     1321 gcgagggtgg cgagcggcgg caggaagcgc atcaccgtgc ccgcgttgcc cacgtcgacg
     1381 gtggccgggc cgcgcaggcc cgacgggatg atccgccacg cctcgccgcc cccgccgcgc
     1441 ggcacggcgc tgcccggtgc ggccgagtcc gacgagacgg tctcctcgat gcccacgccg
     1501 agggtgcgca gcgcgtccgc catcagcacg gtgtcgcgcg agcgcagcgg gcggcgcagc
     1561 caccccggct cggccgcgag cgccgccagg accagggctc ggttggtgac cgacttggac
     1621 cccggtacct ggaccgtcgc ctcgacggct ccggtcgcgt acggggcagg ccagagggga
     1681 gtggaaaccg ggttcagggt catgaccgcc actttagtgc gccgaggtcg ccggaccggc
     1741 gcacgggagc gccgccgcct ctcacggaga cgggcggcgg cggcccggaa cggtcacgac
     1801 cggcccagca gccggccgcc gccgccgatc agggagcaga gcgcgaccgc gtggaagaag
     1861 aagagccaga ccgccgccgg ggcgtgggtc aggcgggcga gctggtcggc gtcggagtcc
     1921 ggcgcaccgc cgcgccgccg cttcgactgg agctcgaaca ccggccgcac cccgcccagc
     1981 agcaggaacc agaccgccgc gtaggcgaag accgcctgca cctgggaatc ggcgagccag
     2041 gagaccgcga cgaagaggcc gccggtgatc agcacggtca gcaccccgta ggcgttgcgg
     2101 accatcacca gcagggcgag cagcagcgcc gtcgccgccc acagcagcgc cgtgatgtgc
     2161 ccggcggcca gcagccacgc gccgcccagc ccgaggagcg agggggcggt gtacccggcg
     2221 agggcggtga ggatcatgcc cggcccggtc ggccggcccc ggctcacggt cagcccggag
     2281 gtgtccgagt ggaggcgtat cccctccagc ttgcggccgg tgaccagagc gaccaggccg
     2341 tggccgccct cgtgggcgat ggtgacggcg ttccgcgccg ggcgccaggc cgggccccac
     2401 aggaccacgg cgagggccgc cacgccggtc gccacgacca gccagaactc gggggcggtc
     2461 tgcgtcccgg tgacgcggtc ccacagatcg gcggcgggtg cggtggtggt gctctgcata
     2521 ctcgggcggc tcctcgcagc ggtggggcgc gcgtccgccg ggccccacgt ggtggcggcc
     2581 ggacggccgg gcctggcagt ctggcacgta tgtgcggacg gtacgcggcc acccggagcc
     2641 ctgaggacct cagtgagatc ttcggcgtcg agaaggccga gctgagcgag gcggcggcgg
     2701 acggccagga gacgggggag gccccctcgc cctccgagac cctcgtcccc gactggaacg
     2761 tggcgcccac caaggaggtt cccgcgatcc tcgaccggcc ggtcaagggg agcgacgacc
     2821 cgcgccccgt acggcagttg cggaccctga cctggggtct cgtcccctcc tgggccaagt
     2881 cgcccgacgg cggcgcccgg atgatcaacg cgcgggccga gaccgtccac gagaagcccg
     2941 cctaccgccg ggcgttcgcc gcacgccgct gcatcctgcc cgccgacggc tattacgagt
     3001 gggtgaccgc ccccgaggag cggaagctgg aggaggaggg gaagcggaag cggccccgca
     3061 agcagcccta cttcgtcacc cccgccgacg ggtcggtctt cgcgatggcc gggctgtacg
     3121 agttctggcg cgacccctcc ctgcccgggg accacccgcg cgcctggtgg gtgacgtgtt
     3181 cggtgatcac caccgaggcg gagacggcac cgctcgccgt ggggcccgag gagggaccgc
     3241 gggcgctggc cgacatccac ccccggatgc cgttgatgct gccgccggac cggtgggacg
     3301 cctggctcga cccgtcgcgg acggacgtgg cggagctgcg ggagctgctg gcggcgccgc
     3361 cggaagggct gatgcgggcc tatcccgtgg ccaccgcggt gagcaacgtg cgcaacaacg
     3421 ggcccgggct cgtcaccgag ctggagggac ccgaggtggg caccctcttt tagggcctgc
     3481 ccggcggatc ctcgtggcac agcccgcggc gtccggtgcg tgctctcgcc atgcgcccgg
     3541 atctcccctc gtaccggacg tactcgggtg attcgcgcgt gcggccagag tgcgtgccag
     3601 gcgtcgcggg catcgcgggc ccacgaggat ccgccggaca ggtcctggtg ggcgtcccac
     3661 cccccgcacg gcgcgcacgg cgcccggcac atactcccga cgccccggcc ggaggcccag
     3721 gcagcttcgc cacgagggcc ttcggccggc acaccgagac cacgcagcga ccaccgcgga
     3781 gaccgcaccg gaggtgaagc cccccgaggc ccgcttccgc cgggccggcc ggcggcgggg
     3841 tccgtagcct ggagggaacg gggcgccctc gcagaggtca ggaggcgtga ggtggtgccg
     3901 aatcctccgg ttcagcccgg tggcgatgac ggtgacggcg agggagcggc ccggggcggc
     3961 cgggagtctg tgcgccgggc cttgacggag cgggtggcgc gggcgcggaa gcaggcgggc
     4021 gccgccgagg aggccgcgct gcgcctgggg gacgactgcg aactcgacgt cggggacgcg
     4081 ggctcccggc gcaccgccgt cgaggaggag cggcgtcggg ccgacgaggc gcggagcgcg
     4141 gtccagcggg cggaggcggc cctgcgccgt ctcgacgagg gcgccttcgg acgctgcgtg
     4201 tcctgcggcg cggccgtcgg cccggagcgg ctggcggccc tgccgcacac cgagctgtgc
     4261 gcgccgtgca gcggcgcggg tggccggggg ctgccgcgcg gggccgctca gcaggacccc
     4321 accggtgccc gctcgcgccg tggccgttcc gggcgcacgg tggaaggaga ggcgcggcgg
     4381 gcgccggagc caggagggac ctccatgagt gacaccactc ccggtcaggc cgagggcgag
     4441 cgcgacgagg aggagccggg ccgggaggcc cgcgagcagc ccgcgcggac gaccccctcc
     4501 caggcggagg gggacaggga cgacgaggcg gaggacggct gaggccgggg cacacccgcc
     4561 gccgaggtgc gaggaagcga ggcgaagcgt atgaccggcc acccgcagga ccgcggaccg
     4621 gcgcggatca ccttcatcgg gaatgcgacg ctgctcatcg agtacgggcc cctgacgctc
     4681 ctcaccgacc cgaacttcct gcaccggggg gagcgggcct acctgggcaa cgggctctcc
     4741 tccgccaggc tgctcgatcc cgccctggag ctgagcgagc tgcccggcct ggacgcggtg
     4801 gtcctctccc acctgcacgg cgaccactgg gaccggcggg cacggcgggg actggcgaag
     4861 gacctgccga tcctcaccac gccgcacgcc tcgcggcgcc tgcaaggact gcacggcttc
     4921 tcccgggcgg tcggtctgcc cacctggcag tccgagacgc tggtccgcga aggccgccag
     4981 gtgcgggtga cggccctgcc cggccgccac ggcccggccc tggcgcaccg gctgctgcca
     5041 ccggtcatgg gcagcctctg ggagttcggg gcggccggag cggagccgga ggtacgcctc
     5101 tacgtcaccg gggacaccgt catgttcccc ggtgtgcacg agatcgcccg gcgctgcccc
     5161 gacgtccagc tcgccgtgct ccacctcggc ggaacgacgc tgcccggcgg cctgctggtc
     5221 acgatggacg cgcgccaggg cgtggagatg atgcgcgccc tggaactgcc cgaggtcctg
     5281 cccgtgcact acgaggagta cggcgtgatg cgctcgccgc tggccgactt cctggccgcc
     5341 accgagcgcg agggtctcgg cgaccgggtc gtgcgatgcc gccgcgggga acgggtggcg
     5401 gtcggcccga acggcgccgt ggccatcggc gggccgctcc ggggcgagcg gtgacgggac
     5461 cgggagcggt ctgagcggag gccgccggca ccgggccctc ctccccggtg tcccgcccgg
     5521 tgccgtccgc tgcgagccgg cctcgcccgg ccggtgcagg atggccggat gaacgcaccg
     5581 acgcctgaga ccgacgtcac ctccgcccca ctgccctcgg gcgaggcggt caccgtcccc
     5641 acgcccggcg gggacgcccg cgtcacctgg ttccgggccc ggcgtccgcg ggccgtgctg
     5701 gcgctcgggc acggggccgg cggcggcatc gaggcccggg acctggtggc gctggcccgt
     5761 gcgctgcccg ggcacggggt gagtgtggcg ctggtggagc agccgtggcg ggtcgccggg
     5821 cggaaggtgg cgcccgcgcc gaagaccctc gacgtggcct ggcgggcggt gtggccaaag
     5881 ctggcggcgc aggggctgcc ggtcgtcgcc ggcgggcgga gcgcgggggc gcgagtggcc
     5941 tgccgtacgg gcgccggtct gggggcgtgc ggcgtactgg cgctcagctt tccgctgcac
     6001 ccgccggggc gcccggagcg cagccgcgcc gaggagctgc tcgggaccgg cctgccgacc
     6061 ctcgtggtgc agggcgggcg ggatccgttc ggccggcccg aggagttccc ggcggggagc
     6121 cacgacctgg ccgaggtgcc ccacggcgac cacggtttcg ccgtaccgag gaaggcgccg
     6181 gtcaccgggg aggagacgct cgccgtgatc accgaggcgg tgggggagtg gctggagcgg
     6241 ctgcccctgg cctgaggcgg ggccggccgg cgccgggaat gccgagcggg cgacggctgt
     6301 tgtgcgggac gaaggtcctg cgacagcgtt gatcacgaga ggaagtccgc cgcatgggtt
     6361 cgaccgtctg cccgagccgc gagcgcgcca ccgacctgga gtggtcggtg ctgcacgtgc
     6421 ccgcgcgcac cggctccggc cgcgatcgcc gggaagtcca ggagcgtggt ctatcctccg
     6481 attcgggcgg tccggacggc ggacccgcca cagcgctgaa ggaggtgggt ccggtcacgg
     6541 ggaccgacgc gggaagcaag gacgacgtgc cggagaagcc cgaggagacc tcggcggagc
     6601 ggaccgcgcg gttcgagcgg gacgcgctcg ccttcctcga ccagatgtac tcggcggccc
     6661 tgcggatgac ccgcaacccg gccgacgccg aggacctggt ccaggagacc tacgccaagg
     6721 cgtacgcgtc cttccaccag ttccgtgagg gcaccaacct caaggcgtgg ctctaccgga
     6781 ttctcaccaa caccttcatc aactcgtacc gcaagaagca gcgtgagccc cagcgcagcg
     6841 ccgccgagga gatcgaggac tggcagctcg cgcgagccga gtcgcacatg tcgaccggtc
     6901 tgcgctcggc ggagtcgcag gcgctggacc accttcccga ctccgacgtg aagtccgccc
     6961 tccaggcgat ccccgaggag ttccgcatcg ccgtgtatct ggccgatgta gagggctttg
     7021 cctacaagga gatcgcggac atcatgggta cacccatcgg gacggtgatg tcccgcctgc
     7081 accgcggccg ccgccagttg cgcggcatgt tggaggacta cgcccgcgag cgcgggctgg
     7141 tccccgccgg ttccggggcg agcgcggcgg aaccgaacga ccggaaaggc gcgggctcat
     7201 gagctgcgga gagccgcacg agacggattg ctcggaagtc ctcgaccatc tctacgagtt
     7261 cctcgaccac gagatgcccg acagtgactc caacaagatc cgcacgcact tcgacgagtg
     7321 ctccccctgc ctggagaagt acgggctgga gcaggccgtc aagaagctgg tcaagcgctg
     7381 ctgcgggcag gacgacgtcc ccgcggacct gcgtgacaag gtgatcagcc ggctggacat
     7441 gatccgtgcg ggccagaccg tcccgcagca cgacatcgtc tccacggaag cggcggacag
     7501 ctcctgacca ccggctgacg cgggagcggg ggccgtactc cggtacggcc cccccgcgcg
     7561 tgccccccgg gcccccgtcc ccggcggagg gcgaccgggc gggtacagcc cgggcggccc
     7621 acaggcaagt cactcgatag agcgaccccg ccgaggaggg tctgcacctc acaccagtgg
     7681 gtaacccatg ggtaatgagc gacgccccaa ccgtccgtgg ttggatgcga agaggctccc
     7741 cgcccgtccc ggcccagcgc cggcgcccgg gtgagggacc cgaagggacc ggacaccggc
     7801 aggcgggaat cgtgaggatc ttcggcaagg gacggcaccg cccctccgcc tcctggcggc
     7861 aggcgaccga ccgagcgttc accttgatcg gcgacggccg ctacgaggac gcgggcgcac
     7921 tgctcacgcg cgccgccgac ctggaaccct ggctctccga gtcctggttc aacctcgccc
     7981 tgctccacaa gttccgccac gactgggaac aggcccgcac cgcgggcctg cgcgccgtcg
     8041 ccctgttgga ccgggacacc ggcgcccccg actggtggaa cgtcggtatc gccgccaccg
     8101 ccctccagga ctggccgctg gcccgccgcg cctggcaggc gtacggcctg aagatccccg
     8161 gtgaggcggc cgcctccggc gagccgtccg ggatggggct gggcagcgcc gccgtgcgca
     8221 tctcccccga gggggaggcc gaggtggtct ggggccggcg gctggatccc gcccgcatcg
     8281 aggtgcagtc gatcccgctg ccctcctcgg ggcgccgctg gggcgaggtg atcctgcacg
     8341 acggggtccc gcacggcgaa cggaccaccg cctcggggga cacgtacccg gtcttcgacg
     8401 agatcgagct gtgggcgccc tctccggtgc cgacctgggt ggtgctgctg gaggcgcagg
     8461 agccggccga cagggacgcg ctggagctgc tggccgcgga cgccggtttc gccgccgagg
     8521 actggtcgtc gtcggtacgg ctgctctgcc ggacctgctc ggagagccgg atgccgagcg
     8581 acgagggcgg cggcgagcgc cacgtcgacc cgcacgacca cagcgagccc ggccagcccg
     8641 ggccgctcgg ccaccgggac accggcggcg agggcgacct gtgggtgccc gagcgcgagt
     8701 gcggcatcgc cgctccgccc gccctggtgc gcggcctgct cgacggctgg gtcgccgaca
     8761 gcccggacag ccgctcctgg cgggacctgg aagaggtctg ctgatccgcc tccggccgcc
     8821 ccggcgcccg ccggtccgct ccgcgcggcc ctcggtgccc ccgtccccgc gtaggctgta
     8881 cgggcacgga caacgggttc ccaggaaggc gcggaagcgg acatggcgca gcaggacacg
     8941 gagcagcagg cggtggcggg cggtgtgctg ccggtcgacg acgaggggtt cgtcatcgac
     9001 accgaggaca ccgaggagcg tgaggcggcc taccgcgccc ggggcaccgc gcgtccgatc
     9061 accgtggtgg gcaacccggt gctgcatcgc gagacgaagg acgtgacggt cttcgacgcg
     9121 gagctggccg agctggtgga cgacatgttc gccagccagc gggcggcgga gggcgtgggc
     9181 ctggccgcca accagatcgg cgtggacaag aaggtcttcg tctacgactg cccggacgac
     9241 gagggcgtgc gccacgtcgg cgtggtctgc aacccggtcc tcgacgagct gccggccgag
     9301 cgccgtgtgc tcgacgactc caacgagggg tgcctgtcgg tccccaccgc ctacgcggag
     9361 ctggcccgcc ccgaccacgc ggtggtgcgc ggtcaggacg agaagggcaa cccgatcgtg
     9421 gtgcgcggca ccggctactt cgcccgctgc ctccagcacg agaccgacca cctgtacggg
     9481 tacctctaca tcgaccggct ctccaagcgc gagcgcaagg aggccctgcg gcagatggcc
     9541 gagggcaccc cgcgctacga gacggtgccc aacgactgag gcgcgtcccc tccggcaccc
     9601 cgccgcacgc cgccccgccc cgctctcccc gtacgggagg cggggcggtg gtgtgccgtg
     9661 gcggggtgct gtgctgttcc ggccgctgga gcggccccat gatcaatttt cggacactca
     9721 tggcgatctt cgagtcggcc aggggtggcg aatgaagcaa atctgttccc tgattggtca
     9781 gttgtagtgc tcaatggaaa gggcgggggg acacaccacc gcgcggtccc cacgccgagt
     9841 ggggcaccgg cagaaagcgg atgaaagggg tttgttcgtg cctgctttcc cacacagtgc
     9901 cgcacgggcg cagacgactt cggtgcccga ggcgctggcg ttgcccgtga tcgaacaagc
     9961 gtttccgcga catcgccatg agtattggcc aaagcttcag gtggagtccc gtgcctggct
    10021 gctcgaaaaa cgtctgatgc ccgccgacaa ggtcacccgc tatgcggacg agctccgcta
    10081 caccgacctc atcgccggct actacgtcgg cgcgccgagg gaggtcatct cggcgatatc
    10141 cgacttcagc acctggttct tcgtctggga cgaccagcac gaccgggacg ccgtccacgg
    10201 gcggcgcgat tcctggtacc ggctgagcgc cgacctgcac accgcgctgg acgcccccgg
    10261 cgaccacctg gcccacccgg agccgctggt ggcggccttc gccgagaccg tccaccggct
    10321 gggcggcttc ctcagcgccg actggaaccg ccggttcgcc cggaacttcc acgccatcgt
    10381 cggtgcctac gaccaggaat tcgagaaccg cgtcaccaag gtcaccccga gcgtggccga
    10441 ttacatcgaa ctgcggcgtc acaccttcgg tcattccgtc tggatcgacc tcctcgaacc
    10501 gacggcgggg cgtgaaattc ccgaatccct gcgcacgagc gggccgttca tggcggcggc
    10561 ccgtcactgc caggatttct ccgcctggta caacgacctc tgctcactcc cgaaagaact
    10621 cgccggcgac gaccagcaca atctgggaat cagcctcata cgtcatgagg gtctgtcgct
    10681 cgaagaggcg gtgacggagg tgaggaaacg cgtggagaac tgcgtcacgg aattcgaggt
    10741 ggcggagaag gaattgcggg aactcctcga cggacatctc gccgcgctgc ccggcgcggc
    10801 cgcttcggaa gaggcacggt ccgtcgcgga ggcggtgggg tccgccgtct tcaacatgcg
    10861 caactggttc tcctcggtct actggttcca ccacgagtcc ggccgctacc gcgtcgacag
    10921 ctgggacgac cggagcaccc cgccgtacgt cagcgacctg gcaggtgacg cgtgagcacc
    10981 gaacccgtca tcgagcgccc cgccgccccg ggcccgcgca ccgcgcccct ggtggccggc
    11041 agcgtgcccg tgctcggcca cgccccgagc ctggtccgcg acccgctcgc cttcctcacc
    11101 gggctgcgcg accacggtga cctggtccgc gtgaagctcg gcccgaagac ggcgtacgcg
    11161 gtgtgcgcgc cggagctggt cggggcgctg ctgcgcaact cccaggagtt cgtggtcggc
    11221 gggccgctct gggagaacct ggaggtcctg ctcggcaagg gggtggccac cagcaacggg
    11281 gccgaccacc gccgccagcg gcgcatgatg cagcccgcct tccggcccga gcggatcgcc
    11341 tcgtacgcga ccgtgatgga ggaggagtcg cgggcgatgg ccgaccgctg gcgcgacggg
    11401 caggtggtcg acatcggcgc cgagacgttc agctgcgcgg tgcgggtggt cgcccgttcg
    11461 ctgctggagg tggactcgat cggcgccaag gccgaccgga tcagctcctc cctgcacacc
    11521 gtcttcagcg gcctgtaccg gcggatgatc ctctccttcg ggccgctgca ccggctgccc
    11581 acccccgcca accgccgctt cgaacgggcg ctggccgacc tccaccagct cgtcgacgag
    11641 gtgatcgccg aacgccacgc ggagggcaag gggcccgacg acctcctcga cattctgctg
    11701 accgccgagg acggcgaggg ccggcccctc agcgatcagg agattcacga ccatctcgtc
    11761 tccttgatcg tcgcgggggc cgagaatgtc gcctcgacac tcgcctggtg cttccagctc
    11821 ctcaccgaac accccgcgga ggaacagcgg gtggccgagg aggcactatc cgtggcgccg
    11881 ggccgaccgg tggatttcgg cgatctgggc tccctggagc acacccgcaa tgccatcgtc
    11941 gaatcgatgc gcatacgccc cgcggcgtgg atattcacgc gccgcgccgt cgcggacacg
    12001 gaactcggtg gctatcgcat tccagccggt gcggacatca tctacagcgc gtatgcgatg
    12061 cagcacgatc cgcgctcatt cgaccggccg gacgtcttcg acccggaccg ctggattcct
    12121 gaacgggccg aaaaggtacc gcagtacgcg atgatgccgt tcagcacggg caaccggaaa
    12181 tgccccggcg accacttcag catggtggag gccacgctga tgctcgccac cgtggtgccc
    12241 cgctggcgac tggtccccgt ccccgagacc gacccggcgc cccgcatcgg gatcaccctc
    12301 cagcccaagc gcgccgtctt ccgggtcgag cgccgctgac ccggggcgcg ccgcggacac
    12361 cgacgcccga cgcccggccc ccgggagggg ccgggcgtcg ggcgtccgcc cgggcgggcc
    12421 cggtcagaag tcgtcgtcga aggagacggt gccctcgacc gcgacctggt aggccgagac
    12481 acggcgctcg aagaagttgg tcagctcctg cacaccctgg agctccatga aggagaacgg
    12541 gttctgcgag ccgtacaccg gggcgaagcc cagccgggtg agccgctggt cggcgacgca
    12601 ctccaggtac tcgcgcatcg actcggtgtt catgccgggc aggccctcgc cgcacaggtc
    12661 gcgggcgaac tggagctccg cctcgaccgc ctccttcagc atcgcgacga cctgctcctg
    12721 gagcctgtcg tcgaacagct ccggctcctc cttgcggacc gtgtcgacca cgtcgaaggc
    12781 gaagctcatg tgcatcgtct cgtcgcggaa gacccagttg gtaccggtcg ccagcccgtg
    12841 cagcagcccg cgcgagcgga accagtacac gtaggcgaac gccccgtaga agaacagccc
    12901 ctcgatgcag gcggcgaagc agatcaggtt gagcaggaac ttgcggcggt ccgcctggct
    12961 ctccagctgg tccagcttgt ccaccgagtc catccagcgg aagcagaact ccgccttctc
    13021 gcggatcgag gggatgttct ccaccgccgc gaaggcgtcc gcgcggtccg ccgggtcggg
    13081 caggtaggtg tcgagcagcg tcaggtagaa ctggacgtgc acggcctcct cgaagagctg
    13141 ccggctcagg tagagccgcg cctcggggga gttgatgtgc ttgtacaggg tgagcacgag
    13201 gttgttggcg acgatcgagt cacccgtggc gaagaacgcg accagccgcc cgatcaggtg
    13261 ctgctccccc ggggagagct tcgccaggtc ggccacgtcg gagtggaggt tgacctcctc
    13321 gacggtccag gtgttcttga tcgcgtcccg gtagcgttcg tagaagtcgg ggtaccgcat
    13381 gggacgcagg gtcagctcga agccggggtc gagcaggttc ttcgccgtgc ccacggtgtg
    13441 cgcgttcgct gccggggtgg tgtcgggggt ggtcattact ggcatgcctc gcaggactcg
    13501 gggttctcca gggagcaggc gacggcatcc gcttcggggg ccgcctgcgc cgggacggtg
    13561 gcgggggcgg agccgccggc ggcgcgggcg atccgcgtgg ccggacggga ccgcaggtag
    13621 tacgtggtct tcagcccctt cttccaggcg tacgcgtaca tcgagctgag cttgccgatg
    13681 gtgggcgtct ccatgaacag gttcagcgac tggctctggt ccaggaacgg ggtccgggcg
    13741 gccgccatgt cgatcaggcc gcgctgcggc agttcccacg cggtgcggta cagcgcccgc
    13801 agctcctcgg gcacccaggc gaagccctgc accgaaccgc tggcctcgcg cagcgcctcg
    13861 cgggtccgcg cgtcccagac gccgagccgc ttcaggtcct cgaccaggta ggagttgacc
    13921 tggaggaact cgccgctgag ggtctcgcgc ttgaagaggt tggagacctg cggctcgatg
    13981 cactcgtaga caccggcgat cgaggcgatg gtggccgtcg gggcgatcgc gaggagcagc
    14041 gcgttgcgca tgccgctccg cgcgacccgg gcgcgcagcg cctcccaccg ctgtggccag
    14101 gccaggtcgg tgtcgtagtg gtccggatgg agcacaccct gagcggtgcg ggtgcggtcc
    14161 cagttgggca gcggcccgtt cctctcggcg agttcgcagg aggtctcgta cgcggtgagc
    14221 atgatgcgct cggcgatccg ggtggagagc cggcgggcct cgggggagtc gaaggggagc
    14281 cggagctgga agaggacgtc ctggaggccc atggctccca ggcccaccgg ccgccagcgg
    14341 gagttggagc gctcggcctg ttcggtgggg tagaagttga tgtcgaccac gcggtcgagg
    14401 aagaccacgg cggtgcgcac cgcctcgtcc agccgctccc agtcgagggc gccgccggtg
    14461 acgaaggcgc cgaggttgac cgagccgagg ttgcagacgg ccgtctcgcc gtcgtcggtg
    14521 acctccagga tctcggtgca gaggttcgag gagtgcacgg tgtggccggg cagcgccgtc
    14581 tggttggcgg tgcggttgga ggtgtccttg aaggtcatcc agccgttgcc ggtctgggcg
    14641 agggtgcgca tcatccggcc gtacagctca cgcgccggga tggtccgctt ggcgagtccc
    14701 gcggcctcgg ccgcgcggta ggccgcgtcg aaggccgccc cccacaggtc ggtcagctcg
    14761 gggacgtccg agggggagaa gagcgaccag tcggcgtcgg cgtcgacccg gcgcatgaac
    14821 tcgtcgggga tccagtgcgc gaggttgagg ttgtgggtgc gccgggcgtc ctccccggtg
    14881 ttgtcgcgca gctccaggaa ctcctcgatg tcggcgtgcc aggtctccag gtagaccgcg
    14941 gccgcgccct tgcgccggcc gccctggttg acggcggcca ccgaggcgtc gagcgtgttg
    15001 aggaacggca cgatgccgtt ggagtgcccg ttggtaccgc ggatcagcga accccgggcg
    15061 cggatgcggg agtaggccag gccgatgccg ccggcgtgct tggagagccg ggcgacctgg
    15121 tggtaccggt cgtagatcga ctccagctcg tccttggggg agtccagcag gtagcaggag
    15181 gacatctgcg ggtgccgggt gccggagttg aagagggtgg gggaggaggg caggtaggag
    15241 agggcactca tcagccggta gagcgaggcg acctcgtcga gggcctggac cgactcgtcc
    15301 gcggcgagtc cgcaggcgac gcgcagcatg aagtgctggg gtgtctcgat gacctggcgg
    15361 gtgtgcgggt ggcgcagcag gtagcggctg tgcacggtgc gcaggccgaa gtagccgaag
    15421 cggtcgtcgg ccgccggatc gaccagggcg tcgagccgct cggcgtgcgc ggtcacgaaa
    15481 gcggcggtgc ggtccgcgat caggccctcg cggtggccgg tggcgaccga ctcggtgaag
    15541 gcggtgacgc cctggcccgc ggcctcctcg gcgatggtgc gggccagcag gcgggcggcg
    15601 agccgcgagt aggcggggtc ctcggagatc agaccggcgg cggcctccgt cgcgagggac
    15661 cgcagctcgg cctcgtccga ggcggcgttg cggccccgga gcgcggcggc ggcgacccgg
    15721 ccggggtcgg tgtcggggag atccgcggtg aggtcggtga gggtacgcag cagcgcgccc
    15781 ccggggccct ggatctcctc ggcccgcacc tcggccgtcg acggatcggc tggcgcgatg
    15841 gtcatgaagc tctccctcgc tcggcacgga gccacgcgga gggcagcgga tacgacggac
    15901 ggccgggctc tggggcacac ggctccgcac gcgtccgcga gcccattcca cgaggcccgg
    15961 acgacatcgg cacccgggcc ggacggccgg ggtgcgccgt cggcaggtcc tcggactcgc
    16021 gggcgcgcag aagcgcacca acacaccgtt gcgggacagt tccggacttc caccggattc
    16081 ccctgcggcg acagcgagca tgagcataca tcttgtgccg cgctcgggaa gcggccccat
    16141 atcttgtgtc gggtgtgccg tgaggtgggc cattcgaccc acccgtaccg gatgcccgaa
    16201 ccgggcggag gacccctcgg acagggcccg gacgcccgcc ggaagggccc gggagcagct
    16261 ccgggaaggc cctgggcggc gccttccggc agagcccgcg cggggcgcct cccggaagcg
    16321 cgtgaagcgg cgcgacggcc tcggagagcg tacgcgcacg ggctccgggc ccgggtgcca
    16381 ggggccgcgt gacggtaccc gagggcgagg ccggcgacag tgcggtgcga cgcggtccgg
    16441 gctggacgag gggacgactc ggttcgggcg gtggacgtgg ggcgccggcg gtgcggcacg
    16501 gtcctggccg ggggcgtgag ccggcccaga cgaggggagc cggcccggtg ccgtcgaaag
    16561 ggcccgcccc ggcccgggcc cgaggccgtg ccccctcgcc ggagaccggc cggaccgtcc
    16621 gccgggcctt cgcgcgtacc gccccggtca ggccgggaaa cggcgaagcc gccgaccccg
    16681 ggagggccgg cggcttcgcc gtgcggtcag cagcagcgga atccgtcccg tggatccgcc
    16741 tcgcgggcgt ccatgcggct gcgttcgaac tgcctgcggg tcatcacctc ggcgtccggg
    16801 tcgtggcgcc ggaggtgcgc ggcgtacttc tcgtacgccg tctcgcccga cacctcccgg
    16861 acgtaccagc cgatccagcg cgcgccggcg cgcaggcggt gcgccaggac gccgaggcgg
    16921 ccggggcggt gggccgcctc gccgctcatg ccttgccgcc gccctgcccg gcgggggcgt
    16981 cgtcggccga gacgggggcc ccggcgccga cgagggccag ttcggccttc tcctcggcgg
    17041 tggggaacat ccccgccggg gcgacgatct tcgactgctc gaagggcgcc tcggccatct
    17101 tgaccgactc gggcctgcgg atcgcgttgt agctgacgcg gcccgcgtcg accaggacga
    17161 tgatgatcag caccgcgaag acgatcgaca ggactccgtc cacggtggag ttggtcacca
    17221 cggtgtgcat gtcgctcatc gacttggccg gagccagcac ctcgcccgcg tcgatgccgt
    17281 cctggtactt ggcgcgctgg gcgaagaagc cgatggccgg gttgtccgag aagaccttct
    17341 gccagctcgc ggtgagcgtg accgccacgt cccagacgag cgggacaccc gtcacccagg
    17401 cccacttgag gcggcccgac ttgatcagca gcgtggtgca gacggcgagc gcgacggcgg
    17461 ccagcaactg gttggcgata ccgaagagcg ggaagagctg gttgatgccg cccagcgggt
    17521 cgtgcacgcc gacccagagg aagtagcccc agcagccgac cacgaccgcc gaggtcagcc
    17581 agacgcccgg ccaccagctg acgcggcgca tcggcttcca gacgttgccc agggtgtcct
    17641 ggagcatgaa gcggccgacc cgcgtcccgg cgtcgacggt ggtgaggatg aagagcgcct
    17701 cgaacatgat cgcgaagtgg taccagaacg ccttcatccc ggcgccgccg agtgccgacg
    17761 cgaagatctc cgccatgccg agggcgaagg tcggcgcgcc accggtgcgg gacagcaggg
    17821 aggcctcctc gacgtccttc gccgcctggg ccagttggtc cgggctgatg gtgaagccga
    17881 ggttggcgac cgcctccgag gcgctgttga ccgtgtcgcc gaggacaccg gccggggagt
    17941 tgatggcgaa gtagaggccc gggtcgatga tgcaggcggc gatcatcgcc atgatggcga
    18001 cgaaggactc ggtgagcatc gcgccgtagc cgatcatccg gatctgggtc tccttctgga
    18061 ccatcttcgg ggtggtgccc gaggagacca gggagtggaa gccggagagc gcgccgcagg
    18121 cgatggtgat gaagacgaac gggaagagcg agccggagaa gaccgggccc gcgccgctgg
    18181 tcgcgaagga ggtgacgccg tccatcttca gcgtcggcat cgcgatgacg acgcagaccg
    18241 ccatcagcac gatggtgccg accttcatga aggtggagag gtagtcacgc ggggcgagca
    18301 gcatccagac cggcagtacc gaggcgaaga agccgtagac caccatccag atgaccaggg
    18361 tgcccggctc cagggtgaag aagtccgcca tggaggactc cgcgacccag ccgccgccca
    18421 cgatcgccag cagcaggagg gcgacgccga ggacggagac ctcggtgacc ttgcccgggc
    18481 gcatcgtgcg caggtagacg cccatgaaga gggcgatcgg gatggtcatg ccgatggaga
    18541 agacccccca cggcgaaccg gccagcgcgt tgacgatgac gagggccagc accgccagca
    18601 ggatgatcat gatcatgaag accgcgatca gggcggcgac accgccgacc gggccgatct
    18661 cgtcccgggc catctggccg agcgaacggc cgttgcggcg ggtggagaag aagagggtga
    18721 ccatgtcctg gacggcgccg gcgaagatca cgcccgccac gatccagatg gtgcccggca
    18781 ggtaccccat ctgtgccgcc aggatcgggc cgacgagcgg acccgctccg gcgatggccg
    18841 cgaagtggtg gccgaagagc acccggcggt cggtcggctg gaaatcgacc ccgttgtcca
    18901 ggcgctccgc cggcgtggcc cggtccttgt cgaccttcag gaccttgttg gcgatgaagc
    18961 gcgcgtagaa gcggtacgcg atggcgtagg agccgagggc cgccgccagc atccagatgg
    19021 cggagatctc ctcgccccgg gagagcgcca gcacgctcca ggcgatggcg ccgaccacgg
    19081 cgaccagcgt ccagacggcg atggacttgg cggacagctt ccggtttccg gaggcgggtg
    19141 gagccggctc ggccatgatg gtcccctcac atgagcgcag gtggacccac ctgcgctgaa
    19201 ctcctgcgat gcgtcggaaa tgtaggcgac cggtccgggc tttggcaccc cctgtccgcg
    19261 tatcggaacg gcaacgactc cggatccggc acaaccttcc gccgggaccg ccgcgtccgc
    19321 gtcccttaag cacgcctcgc cgcgtatttg tcctccgcga ggcgctgctc ccgcccctcg
    19381 cggcccttcc tcgaccgccc cctgccgtgc tcctcgggtg gtgggtgcgt acccgccgcc
    19441 acccgtgggt catgcacgga agagcacaca cgtacgagcg aatcggccgg agagggccgt
    19501 gcggggcgag gggtctccct cgggtggtgg gagagcggcg ggcgaattcg cgccaggcgc
    19561 ggcgccgctc gcccgccggg cacggcgaag ggcggcaccc ctcgccgagg ggtgccgccc
    19621 ttccgtccgt acccgcggcg gccggccctt ccgggcggcc gcccgcgcct actccaccgg
    19681 ccgcttcagc cgggccagga acttgtaccg gtcgccccgg tagaccgagc gcacccactc
    19741 gacgggcgcc cccgtctcgt cgcgggagtg gcgcgagagc atgagcatcg gcaggcccac
    19801 gtcagtggcg agcagggccg cctcgcgcgg ggtggcgagc gaggtctcga tggtctcctc
    19861 ggcctcggcc gggcgcacgc cgtacacctc gtacagggcc gtgtagaggg aggtgtactt
    19921 gaccagggag cggcgcaggg cggggaagcg cttggccgac aggtgtgtcg tctcgatcgc
    19981 catcggctcg ccgctggcca gtcgcagccg ctcgatgcgc agcacccggc tgcccgcggt
    20041 gatgtcgagc agggcggcga gcgagtcgtc ggcggtgatg tagccgacct ccaggagctg
    20101 cgaggtgggc tccaggccct gggcgcgcat gtcctcggtg taggaggtga gctggagtgc
    20161 ctgggagacc ttgggcttgg ccacgaaggt gcccttgccc tggatgcgtt cgagccggcc
    20221 ctcgacgacc agctcctgga gtgcctggcg caccgtggtc cgcgaggtgt cgaactcggc
    20281 ggcgagcgta cgctcgggag gtacggaggt gcccgggggc agcgtctgcg tcatgtcgag
    20341 caggtgccgc ttgaggcggt agtacttggg cacgcgcgtg gcccgtaccg gactggtggg
    20401 ctccgtggcg ggtccgccgg ccgtccgggt cctcgttccg cccgcgtccg tcgtcatact
    20461 ccgcccctcc ggctcctgtg ctgctgccgt caccggctcc tccgtctgtc gcggatcaca
    20521 tcgtggcacg gccggtgatc gccggtccgg actccctcag gtgtcggtcc gataacggac
    20581 gcgactgccc ttcttataca cccttgacac ccctaaaggt ctaggccaag ctccgcttac
    20641 tggtctacac cattaaagac cagatcccag tcccacgggc agtaactcgt cttcgatgtc
    20701 atcgctgcgg gtggggggta aagggttccc tgaggagggt gacgtgaagc gcaagctcat
    20761 tgcggccatc ggtgtcgctg gcatgatggc cggtctcgcg gcgtgcgggg actcggagac
    20821 ggcgagcaac gccaagcccg aggaccgcaa ggaaaacctg accgtctggc tgatggtcga
    20881 cgcccagagc acctggcccg agctggtcaa ggacgtcaac gcccagttca agaagaagta
    20941 ccccaacgtc aaggtgaacg tccagtacca gggct
//
