LOCUS       NZ_CP045704            45898 bp    DNA     linear   CON 03-SEP-2024
DEFINITION  Streptomyces rutgersensis strain NBH77 chromosome, complete genome.
ACCESSION   NZ_CP045704
VERSION     NZ_CP045704.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces rutgersensis
  ORGANISM  Streptomyces rutgersensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces diastaticus group.
REFERENCE   1  (bases 1 to 6848830)
  AUTHORS   Benaud,N., Edwards,R.J., Amos,T.G., D'Agostino,P.M.,
            Gutierrez-Chavez,C., Montgomery,K., Nicetic,I. and Ferrari,B.C.
  TITLE     Antarctic desert soil bacteria exhibit high novel natural product
            potential, evaluated through long-read genome sequencing and
            comparative genomics
  JOURNAL   Environ Microbiol 23 (7), 3646-3664 (2021)
   PUBMED   33140504
REFERENCE   2  (bases 1 to 6848830)
  AUTHORS   Benaud,N., Edwards,R.J. and Ferrari,B.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2019) School of Biotechnology and Biomolecular
            Sciences, University of New South Wales, Botany St, Sydney, NSW
            2052, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-DEC-2018
            Assembly Method                   :: FALCON v. v 1.8.6
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014216335.1-RS_2024_09_03
            Annotation Date                   :: 09/03/2024 04:34:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,921
            CDSs (total)                      :: 5,831
            Genes (coding)                    :: 5,642
            CDSs (with protein)               :: 5,642
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 189
            CDSs (without protein)            :: 189
            Pseudo Genes (ambiguous residues) :: 0 of 189
            Pseudo Genes (frameshifted)       :: 102 of 189
            Pseudo Genes (incomplete)         :: 130 of 189
            Pseudo Genes (internal stop)      :: 14 of 189
            Pseudo Genes (multiple problems)  :: 50 of 189
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:08:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4314697
            Orig. end                         :: 4360595
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045704.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Belinda Ferrari, QAP Lab
            4002, Bioscience South E26, UNSW Sydney, Australia 2052 (Quarantine
            regulated isolate).
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..45898
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="NRPS"
                     /product="NRPS-like"
                     /region_number="11"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..45898
                     /SMILES="NC([*])C(=O)NC(Cc1ccc(O)cc1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..43111
                     /SMILES="NC([*])C(=O)NC(Cc1ccc(O)cc1)C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..43111
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:23111](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..23111
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            complement(856..1626)
                     /locus_tag="F0345_RS18200"
                     /old_locus_tag="F0345_18240"
     CDS             complement(856..1626)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004987131.1"
                     /locus_tag="F0345_RS18200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18240"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_100456714.1"
                     /transl_table=11
                     /translation="MTTTPLASRSTEVAARATELSKVYGTGETRVVALDQVSIDFRQGE
                     LTAIMGPSGSGKSTLMHCVAGLDTFDGGSVRIGDTELGALKDKQLTQLRRDKIGFIFQA
                     FNLLPTLTALENITLPMDIAGRKPDQGWLDQVIDMVGLRDRLKHRPAQLSGGQQQRVAV
                     ARALASRPEIIFGDEPTGNLDSRSGAEVLGFLRNSVRAMNQTVVMVTHDAVAASYADRV
                     VFLADGRIVDEMHRPTADSVLDRMKEFDAKGRTS"
     misc_feature    2195..2211
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 19.04"
                     /tool="antismash"
     gene            complement(2330..2809)
                     /locus_tag="F0345_RS29925"
     CDS             complement(2330..2809)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016144.5"
                     /locus_tag="F0345_RS29925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GrpB family protein"
                     /protein_id="WP_238156465.1"
                     /transl_table=11
                     /translation="MGARPAGLPHHVEHAGPPSIPALPAKPAPDLPLTVPGPADEDAYV
                     PAPALARLGPRPTIRRPDRNEHRLLRGAPTHPGGERRRPARPPRDRPYAPLPRPTRAPP
                     RPTATCTRPPSTSRPGARGGTPSSEGTRGAGWWRRCRAGRGGAEVPGTGLEPVRP"
     gene            3174..4169
                     /locus_tag="F0345_RS18210"
                     /old_locus_tag="F0345_18250"
     CDS             3174..4169
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008417706.1"
                     /locus_tag="F0345_RS18210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18250"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_100456712.1"
                     /transl_table=11
                     /translation="MVFGSGGAGGGGDAVVDVRDLWMRYGEKDVLRGISFEIRRGEVLG
                     LLGPNGAGKTTTIEILEGFRQPSSGHVRVLGVDPLKGDDAWRARVGVVLQSWRDHSRWR
                     VGALLEQFASYYRPYTGRDGYPGPYEVAELLARVGLSDKAETKAGALSGGQRRRLDVAV
                     GIVGRPSLLFLDEPTTGFDPKARGDFHDLVHALSDLEDTTVLLTTHDLAEAEKLADRIL
                     ILDGGGIVADGSSEQLARQVAGEDEVRWTRHGVREVHLTPDGTRFTRELFERHGEEVTE
                     LEVRRASLEDTYLRMVAQSEAEAGAPGSVPGEAEPAPGTGPARERTGEPA"
     cand_cluster    3181..45898
                     /SMILES="NC([*])C(=O)NC(Cc1ccc(O)cc1)C(=O)O"
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    3181..45898
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[23180:25898](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      23181..25898
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
     gene            4166..5065
                     /locus_tag="F0345_RS18215"
                     /old_locus_tag="F0345_18255"
     CDS             4166..5065
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008417704.1"
                     /locus_tag="F0345_RS18215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18255"
                     /product="ABC transporter permease"
                     /protein_id="WP_229831609.1"
                     /transl_table=11
                     /translation="MSEAVSGAGEREREAARFAWGHGYGPGVRRGATEFLNSLRTPADV
                     GYYIVGSAVFLVVMFLNRHSVDETTGVSAGALMLPGVLGFTIIFGALFGLATAVSTERE
                     DGTLLRAKSLPHGTTGYVVGQSTRAALEVVLSLVLLLVPGLILLDNAWSGGVWGVPHAA
                     SLVLLGVLASTPLGFAVGSLVKNPRALGGWGFMLMSGLVGISGTFFPLSVLPGWVAGLA
                     QVFPLYWLGHGLRSAMLPDAAAAGEINGSWQVWESYAVLGAWALLGLVLAPVLLRRMAR
                     RESGASMSARRETALQRY"
     gene            5076..5342
                     /locus_tag="F0345_RS18220"
                     /old_locus_tag="F0345_18260"
     CDS             5076..5342
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950363.1"
                     /locus_tag="F0345_RS18220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18260"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_100456711.1"
                     /transl_table=11
                     /translation="MTPRTEGAGPGAGAGPDPVHNRIAMLRVERHVTRRQLADALGVHY
                     QTIGYLERGEYSPSLHLALRIAAYFGVPVEFVFSLTPFAPLKP"
     misc_feature    complement(5650..5663)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.89"
                     /tool="antismash"
     gene            5678..6610
                     /locus_tag="F0345_RS18225"
                     /old_locus_tag="F0345_18265"
     CDS             5678..6610
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642953.1"
                     /locus_tag="F0345_RS18225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18265"
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="WP_185393347.1"
                     /transl_table=11
                     /translation="MRSSNPVFSRRGFSRDNGHAQFNAAPQAGGPAVGTQQGNPYAGGN
                     PYAGQNPYAGQNPYAQGDQQTYANPYAQDQYGVQAPTTDRMTMDDVVMRTATTLGTLIV
                     TAALAWWFLPVDAANMGKSYGIAVGAGLVAMVLALVQSFKRKASPALILAYAALEGVFL
                     GVVSNVVDTHIANGAAMQAVIGTMAVFTAVLVAYKAGWIRVNRRFYGFVMAAAMGFVLL
                     MAVNLLFAVFGGGDGLGFRSGGLGIIFGIIGVLLGACFLALDFKQVEDGIAYGAPREES
                     WLAAFGLTMTLVWIYMEFLRLIAILQGDD"
     gene            6696..7007
                     /locus_tag="F0345_RS18230"
                     /old_locus_tag="F0345_18270"
     CDS             6696..7007
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950365.1"
                     /locus_tag="F0345_RS18230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18270"
                     /product="hypothetical protein"
                     /protein_id="WP_100456710.1"
                     /transl_table=11
                     /translation="MLDTTPLTSAVDQFADRLRAAPQSKLQRGAAAEALELARELSARA
                     QRLEQPAGEVRVMPDAGMFAVADQVTVAAHDLALVLPGKEALDAAVARVAEARERAGI"
     gene            complement(7116..7916)
                     /locus_tag="F0345_RS18235"
                     /old_locus_tag="F0345_18275"
     CDS             complement(7116..7916)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950366.1"
                     /locus_tag="F0345_RS18235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18275"
                     /product="hypothetical protein"
                     /protein_id="WP_100456708.1"
                     /transl_table=11
                     /translation="MTLALLIALAAVVAVGAVALHAVHGLRRQITALRAELHATRPGRA
                     TVPAARADAEGIREAVAEALAEERERELAEARAFWAAQEARDASDAPSLLGGLHGLVDD
                     LFIPRQADLAGLDALDAAEAASQKPAGEPEEDSPELAAARRRHPSHPDFVPVRPTPVER
                     EGAGDDHETTVAVLEELAQSRTALADVRPGPLGTLDVYVFADGTTLCMTPGHRETAELL
                     AGSLRAGEAPVLLGGSGVSGAYALTFSCGEDNVYLLADRVIASV"
     gene            complement(8232..9452)
                     /locus_tag="F0345_RS18240"
                     /old_locus_tag="F0345_18280"
     CDS             complement(8232..9452)
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006125100.1"
                     /locus_tag="F0345_RS18240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18280"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_164379807.1"
                     /transl_table=11
                     /translation="MPEAVIVSAARSPIGRAFKGSLKDVRPDDLTAHIIETALAKVPEL
                     NPRDIDDLMLGCGLPGGEQGNNLGRIIAVQMGMDHLPGCTVTRYCSSSLQTSRMALHAI
                     KAGEGDVFISAGVETVSRFAKGNSDSLPDTRNPVFAEAEARTAAVAEQGADSWHDPRED
                     GKLPDAYIAMGQTAENLARLKGVTREEMDEFGVRSQNLAEEAIEKGFWEREITPVTTPD
                     GTVVSQDDGPRAGVTLEGVQGLKPVFRPDGRVTAGNCCPLNDGAAALVIMSDTKARELG
                     LTPLARIVSTGVSGLSPEIMGYGPVEASNQALRRAGLSIDDIDLAEINEAFAAQVIPSY
                     RDLGLPLEKVNVNGGAIAVGHPFGMTGARITTTLINSLQFHDKQFGLETMCVGGGQGMA
                     MVIERLS"
     gene            complement(9758..10807)
                     /locus_tag="F0345_RS18245"
                     /old_locus_tag="F0345_18285"
     CDS             complement(9758..10807)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950368.1"
                     /locus_tag="F0345_RS18245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18285"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_185393781.1"
                     /transl_table=11
                     /translation="MARRIAAGAAYGGGGIGLLGVAGVGVLLAEAQLAKRSVGSQGDGA
                     APPRADGVYGRAFGVRPEDGPEVEPLRFLMLGDSTAAGQGVHRSRQTPAALLASGLAAV
                     AERPVELRNVAVPGARSDDLDRQVSLALADGGWVPDVCVLMVGANDVTHRMTATESVRL
                     LASAVRRLRTAGAEVVVGTCPDLGTIEPVYQPLRWLARRASRQLAAAQTIGTVEQGGRT
                     VSLGDLLGPEFAQNPRELFGPDNYHPSAEGYATAAMAVLPTLCASLGLWPEGERPEAAR
                     DEGFLPVARAAARAASEGGTEVAAAGGARGPLALLKRRRRRRITHEPSPAPATGAPAAE
                     GGGLDRRPG"
     gene            10980..12377
                     /locus_tag="F0345_RS18250"
                     /old_locus_tag="F0345_18290"
     CDS             10980..12377
                     /EC_number="4.2.1.22"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004122 - cystathionine beta-synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019343 - cysteine biosynthetic process via
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008417695.1"
                     /locus_tag="F0345_RS18250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18290"
                     /product="cystathionine beta-synthase"
                     /protein_id="WP_164379808.1"
                     /sec_met_domain="PALP (E-value: 5.3e-70, bitscore: 234.5,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHIHDSMVDLVGNTPLVRLNNVTEGIQATVLAKVEYFNPGGSVKD
                     RIALRMIEDAEERGLLGPGSTIVEPTSGNTGVGLAIVAQQKGYKCVFVCPDKVSLDKIN
                     VLRAYGAEVVVCPTAVDPDHPDSYYNVSDRLVRETPGAWKPDQYSNPNNPLSHYHSTGP
                     ELWEQTDGKITHFVAGIGTGGTISGTGRYLKEAGDGGVQVVGADPEGSVYSGGSGRPYL
                     VEGVGEDFWPTAYDRNITDRIVAVSDKDSFQMTRRLAKEEGLLVGGSCGMAVVAALEVA
                     RELGPDDVVVVLLPDSGRGYLSKIFSDEWMNDYGFLDQGGDEPRVGDVLRDKEGDMPHL
                     VHMHPEETVGEAIEVLREYGVSQMPIVKPGAGHPDVMAAEVVGSVVERELLDALFASRA
                     ALDDPLEKHMSRPLPQVGSGEPVADLMAVLGQADAAIVLVEGKPTGVVSRQDLLSFLAR
                     SAGTAVK"
     misc_feature    complement(12976..12987)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    13024..13037
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.73"
                     /tool="antismash"
     gene            13038..13985
                     /locus_tag="F0345_RS18255"
                     /old_locus_tag="F0345_18295"
     CDS             13038..13985
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987083.1"
                     /locus_tag="F0345_RS18255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18295"
                     /product="aldo/keto reductase"
                     /protein_id="WP_185393348.1"
                     /transl_table=11
                     /translation="MRTTELGDGGPAVGRIGLGAMGMSFAYDPRHRDDGTSITVIRRAL
                     DLGVNLIDTADVYGPFANEELVGRALIGRRHEAVLSSKGGVRFDGAEVTLDGRPEYLRS
                     ALEASLRRLRTDHLDLYFLHRVDPRVPVEESWGELADLVAEGKVRALGVSEASADEVRR
                     AGAVHPVAAVQSEFSLFTRDFQDDVVPLCREHRIAFLCHSPLGSGLLSGRYRTRGDLTE
                     GDDRADMPRFTEEAMAANAGLVDRVGAVGRRRGATSAQVALAWLLAQGEHVIPIPGTKT
                     PRYLEQNVAAAELVLSAEDLDELDALPAPTGARE"
     gene            14036..14680
                     /locus_tag="F0345_RS18260"
                     /old_locus_tag="F0345_18300"
     CDS             14036..14680
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024811.5"
                     /locus_tag="F0345_RS18260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18300"
                     /product="HAD family hydrolase"
                     /protein_id="WP_115067891.1"
                     /sec_met_domain="HAD_2 (E-value: 1.2e-25, bitscore: 89.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERFAIFDLDDTLVDSTGAVDRWFIEVSEQRNLGAAGLEFLRAEQ
                     ERPVSPRESFQAIIDRFGFTESPDELRSIFLDRVPRLSRTFDGVLENLAELRARGWRTA
                     LLTNGTEVDQQPKMRDGLADLFDVVCFADDEPMRKPDPEIFRLVADRAGTGLDGAWMIG
                     DSLEHDIAGATAVGMSTIWVSGGRTPQDGESVSGQVVTSVAEAFPLLHAAG"
     gene            complement(14901..15926)
                     /gene="gntD"
                     /locus_tag="F0345_RS18265"
                     /old_locus_tag="F0345_18305"
     CDS             complement(14901..15926)
                     /NRPS_PKS="Domain: TauD (129-319). E-value: 3.1e-15. Score:
                     48.6. Matches aSDomain:
                     nrpspksdomains_F0345_RS18265_TauD.1"
                     /codon_start=1
                     /gene="gntD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF041363.1"
                     /locus_tag="F0345_RS18265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18305"
                     /product="guanitoxin biosynthesis L-enduracididine
                     beta-hydroxylase GntD"
                     /protein_id="WP_100456696.1"
                     /sec_met_domain="TauD (E-value: 2.9e-13, bitscore: 48.6,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKYHLDARANADIDELVRELTRDLSSVHEAAFHRRAAVLAHELP
                     RELRKALVGFRLTEPSGGFLLSGIRIGEEIGPTPADWHQPAGVVSPALREESVFVLCAQ
                     LLGDPFGYATLQNGLMMHDIVPIQGHEKEQISSGSEETLEWHTEEAFHPHRADYTALMC
                     LRNPYGAPTTYAEISDLDITEADRATLRQPLFATRPSGSHSAERNAYTTHLPKSRHALA
                     KESFDRIEEQHRNPPTVSVLFGDEADPYLCVDPDCMTPLTEEAAGALERLCAEINRKLQ
                     DVNLTPGDILFLDNNSAIHGRRPFKARFDGSDRWLKRMNITRDLRRSRSRRLSADDRVV
                     R"
     aSDomain        complement(14970..15539)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F0345_RS18265_TauD.1"
                     /evalue="3.10E-15"
                     /label="F0345_RS18265_TauD.1"
                     /locus_tag="F0345_RS18265"
                     /protein_end="319"
                     /protein_start="129"
                     /score="48.6"
                     /tool="antismash"
                     /translation="HEKEQISSGSEETLEWHTEEAFHPHRADYTALMCLRNPYGAPTTY
                     AEISDLDITEADRATLRQPLFATRPSGSHSAERNAYTTHLPKSRHALAKESFDRIEEQH
                     RNPPTVSVLFGDEADPYLCVDPDCMTPLTEEAAGALERLCAEINRKLQDVNLTPGDILF
                     LDNNSAIHGRRPFKARFDGSDRWLKRM"
     gene            complement(15977..16660)
                     /locus_tag="F0345_RS18270"
                     /old_locus_tag="F0345_18310"
     CDS             complement(15977..16660)
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016115.5"
                     /locus_tag="F0345_RS18270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18310"
                     /product="cyclase family protein"
                     /protein_id="WP_100456694.1"
                     /transl_table=11
                     /translation="MTTAKRDLVDLSHVVRQGMTTYPGLPGPVIEDHMSRVDSRDRYSP
                     GTEFQIGRITLVANTGTYADVPFHRFEGGADLSQVPLSRFADLEGVAVSVPAGSPSGVG
                     PEVFDGLEVTDRAVLVHTGWDRHWATPSYGDPAHPFLTEAAVAWLVARRPALVGIDSVN
                     IDDMADLARPAHTGLLAAGIPVVEHMTGLGQVVGQDFRFHAAPIPVADMGTFPVRAYAL
                     VDREG"
     gene            complement(16657..17874)
                     /locus_tag="F0345_RS29930"
                     /old_locus_tag="F0345_18315"
     CDS             complement(16657..17874)
                     /GO_function="GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1291: argininosuccinate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF044952.2"
                     /locus_tag="F0345_RS29930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18315"
                     /product="argininosuccinate synthase domain-containing
                     protein"
                     /protein_id="WP_100456692.1"
                     /transl_table=11
                     /translation="MHGFLTGLEEIADQPPRHMLLLYSGGVDGTYLLQRLQSLGVRVTA
                     LHLRIGDRESSATAAAHARQFGASFIDVDVTDQFFDVFAPAAVHADAVYQDQFPVGSTL
                     TRPLMARTAVRVAREHGCEVIGHTATYMQNSSIRLSGSIAALAPEIGVAAPFLGSDLPR
                     EAKLAALAEAGISFPEGIHSVDANPWARVIECGSLESPENRLDESVFRWTRDVEDAPAE
                     PAELLLTFRRGLPVALDEAPIAFGDLVERLNLLAGEHGVGRSSGLEDTPFGVKNHEVRE
                     APAATVIIKAHQVMANAVFTAQEHAVRGAIAREWTTTVVQGGWFSHLGESLARCLADLD
                     RPLEGSVRLRLHRGAVTVLSVNSRNGLYYTRFGETFHASMSDYSYTPWLSLATLPSRLR
                     RFGAPR"
     gene            complement(17859..18980)
                     /locus_tag="F0345_RS18280"
                     /old_locus_tag="F0345_18320"
     CDS             complement(17859..18980)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.5"
                     /locus_tag="F0345_RS18280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18320"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_185393349.1"
                     /sec_met_domain="TauD (E-value: 5.3e-07, bitscore: 28.1,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQVREPTQPPAVAGGDPTGSTIAPLDDVAISLTPAEREAAGEVF
                     AASARALKGRPLDDEEVLTEAEFAGLRLPRRILEALGRFRRQGNDAGALLIRNMPVDLA
                     PPATPADGFLSHWNDLPVATFGQLAVASTVGDVIAYADEKLGRLVQDITPVQGDERRQE
                     NSGTVYLELHTEDGFHPSKPDFITLLCIRPDHERVARTVVGAAAGALPLLSERAAGVLR
                     EPRFRLRVSSSFGGGADDLLTEPLPVLSGTAEVPDLLADFHAMDALDEEAGAALEELRS
                     AFLATLRGGVLEAGDLVVVDNRTAIHGRSEFTARYDGTDRWLRRCFAVTDIRSSRADRP
                     AGSRVCHPLRDIGLFVPGPSTTPRIEGPACMGS"
     misc_feature    complement(19576..19590)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.82"
                     /tool="antismash"
     misc_feature    19608..19622
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.08"
                     /tool="antismash"
     gene            20001..23111
                     /locus_tag="F0345_RS18285"
                     /old_locus_tag="F0345_18325"
     CDS             20001..23111
                     /NRPS_PKS="Domain: AMP-binding (11-411). E-value: 1.2e-93.
                     Score: 305.9. Matches aSDomain:
                     nrpspksdomains_F0345_RS18285_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (517-585). E-value: 8.7e-21. Score:
                     65.9. Matches aSDomain: nrpspksdomains_F0345_RS18285_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (604-904). E-value:
                     9.7e-77. Score: 249.8. Matches aSDomain:
                     nrpspksdomains_F0345_RS18285_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="F0345_RS18285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18325"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_185393350.1"
                     /sec_met_domain="AMP-binding (E-value: 9.6e-106, bitscore:
                     352.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.6e-13, bitscore:
                     47.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 9.5e-53, bitscore:
                     177.6, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRSTIHGLIAARARSTPGLPAVEYGDECLDFRELERRSDAAARR
                     LSAHGVAPGVFVAVSLERSAAMVVTLLGILKAGGSYVALDPAYPEARLRWILEDIAPRL
                     AVASRAMRGTVPPAGIPLLVAEELDDASPAHGTDVAPMPGEPGAVPSEGDPERLAFITY
                     TSGTTGRPKGVMHVHDSMTYFMEMIEPYLGLAPGTRFLQFYPLTWEIQALDIYAVLAAG
                     GTVVIPPAGTETAGPGLVRFLRDARVTTALLPPALLAELAEEPPLPALHTLAYIGERCR
                     PRTAERWGSGRRLINLYGPTEVTVAASASDERPPGDAPPIGKALPGRELHVLDEQMNPV
                     AEGAPGELHVGGRGLARGYWRLPELTERQFPQDPFSGRPGSRLYRTGDRVRYLPDGNLE
                     FLGRVDGQLNVRGQRVERGEIEAVMAAHPGVRSCAVVVQGEGSDARLVGFVVGTPGVEK
                     ELGDRLADELPPAMVPSFLVPLERLPLNQHGKVDLAALRAHRRRGAGSRVARPAPRPGP
                     EADLARIWEEVLEVEEVGPEDGFRALGGTSLQAIRAQNRIREHFGVPLTVRELVGAGTL
                     ADLARLLAAGDAGRGALPPLTRTAAGPSHPASLHQRRLWAQARAKQAASVAYNETSALH
                     ITGPVDLSALRRAVQDLADRHEAFRSSLHLDGADLRVDIAAHVTVELAEEDLTGTADPF
                     AAATRRVAELGALPFDLERAPLLRATLLDLGAETRVLVLVTHHTVADGLSQDVLDHDLA
                     QCYAARGAGREPAPRPGKELRPRDHALWQRTTAGHPVLAAGLDHWRAVLDGAPTVTNLS
                     TAGTRSASFSHLGGRVNHETGPELRAAVERLAKEAGTTPYAVCLLALAVLVSRRTGQRD
                     VLIGSPFSGRPSQEAEDVIGFFTNTVVMRVRLDGRLDPLPLLGAVDERIQEGLEHQYVA
                     FNDVVRAVGARGGTSGQPLVQVVLAYQGPLRPRAALTGAHVVPWLVDNGTAKADLTVEI
                     NEVGDELVVVLPYSADVMDEPVAARTLAEYVEILRELTVPRPDTAQS"
     CDS_motif       20034..20138
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F0345_RS18285_0001"
                     /evalue="2.20E+01"
                     /label="C5_starter_265-294"
                     /locus_tag="F0345_RS18285"
                     /protein_end="46"
                     /protein_start="11"
                     /score="-2.1"
                     /tool="antismash"
                     /translation="ARARSTPGLPAVEYGDECLDFRELERRSDAAARRL"
     aSDomain        20034..21233
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F0345_RS18285_AMP-binding.1"
                     /evalue="1.20E-93"
                     /label="F0345_RS18285_AMP-binding.1"
                     /locus_tag="F0345_RS18285"
                     /protein_end="411"
                     /protein_start="11"
                     /score="305.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ARARSTPGLPAVEYGDECLDFRELERRSDAAARRLSAHGVAPGVF
                     VAVSLERSAAMVVTLLGILKAGGSYVALDPAYPEARLRWILEDIAPRLAVASRAMRGTV
                     PPAGIPLLVAEELDDASPAHGTDVAPMPGEPGAVPSEGDPERLAFITYTSGTTGRPKGV
                     MHVHDSMTYFMEMIEPYLGLAPGTRFLQFYPLTWEIQALDIYAVLAAGGTVVIPPAGTE
                     TAGPGLVRFLRDARVTTALLPPALLAELAEEPPLPALHTLAYIGERCRPRTAERWGSGR
                     RLINLYGPTEVTVAASASDERPPGDAPPIGKALPGRELHVLDEQMNPVAEGAPGELHVG
                     GRGLARGYWRLPELTERQFPQDPFSGRPGSRLYRTGDRVRYLPDGNLEFLGRVDGQLNV
                     R"
     aSModule        20034..21755
                     /complete
                     /domains="nrpspksdomains_F0345_RS18285_AMP-binding.1"
                     /domains="nrpspksdomains_F0345_RS18285_PCP.1"
                     /locus_tags="F0345_RS18285"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20214..20255
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F0345_RS18285_0002"
                     /evalue="1.50E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="F0345_RS18285"
                     /protein_end="85"
                     /protein_start="71"
                     /score="12.1"
                     /tool="antismash"
                     /translation="LGILKAGGSYVALD"
     CDS_motif       20475..20534
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F0345_RS18285_0003"
                     /evalue="6.80E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="F0345_RS18285"
                     /protein_end="178"
                     /protein_start="158"
                     /score="24.8"
                     /tool="antismash"
                     /translation="AFITYTSGTTGRPKGVMHVH"
     CDS_motif       20649..20678
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F0345_RS18285_0004"
                     /evalue="8.80E+00"
                     /label="NRPS-A_a2"
                     /locus_tag="F0345_RS18285"
                     /protein_end="226"
                     /protein_start="216"
                     /score="0.8"
                     /tool="antismash"
                     /translation="AVLAAGGTVV"
     CDS_motif       21027..21110
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F0345_RS18285_0005"
                     /evalue="3.90E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="F0345_RS18285"
                     /protein_end="370"
                     /protein_start="342"
                     /score="41.6"
                     /tool="antismash"
                     /translation="GAPGELHVGGRGLARGYWRLPELTERQF"
     CDS_motif       21198..21263
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F0345_RS18285_0006"
                     /evalue="1.30E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="F0345_RS18285"
                     /protein_end="421"
                     /protein_start="399"
                     /score="27.1"
                     /tool="antismash"
                     /translation="FLGRVDGQLNVRGQRVERGEIE"
     aSDomain        21552..21755
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F0345_RS18285_PCP.1"
                     /evalue="8.70E-21"
                     /label="F0345_RS18285_PCP.1"
                     /locus_tag="F0345_RS18285"
                     /protein_end="585"
                     /protein_start="517"
                     /score="65.9"
                     /tool="antismash"
                     /translation="EADLARIWEEVLEVEEVGPEDGFRALGGTSLQAIRAQNRIREHFG
                     VPLTVRELVGAGTLADLARLLAA"
     aSDomain        21813..22712
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F0345_RS18285_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="9.70E-77"
                     /label="F0345_RS18285_Condensation_LCL.1"
                     /locus_tag="F0345_RS18285"
                     /protein_end="904"
                     /protein_start="604"
                     /score="249.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHTVADG"
                     /tool="antismash"
                     /translation="HPASLHQRRLWAQARAKQAASVAYNETSALHITGPVDLSALRRAV
                     QDLADRHEAFRSSLHLDGADLRVDIAAHVTVELAEEDLTGTADPFAAATRRVAELGALP
                     FDLERAPLLRATLLDLGAETRVLVLVTHHTVADGLSQDVLDHDLAQCYAARGAGREPAP
                     RPGKELRPRDHALWQRTTAGHPVLAAGLDHWRAVLDGAPTVTNLSTAGTRSASFSHLGG
                     RVNHETGPELRAAVERLAKEAGTTPYAVCLLALAVLVSRRTGQRDVLIGSPFSGRPSQE
                     AEDVIGFFTNTVVMRVRLD"
     aSModule        21813..25616
                     /complete
                     /domains="nrpspksdomains_F0345_RS18285_Condensation_LCL.1"
                     /domains="nrpspksdomains_F0345_RS18290_AMP-binding.1"
                     /domains="nrpspksdomains_F0345_RS18290_PP-binding.1"
                     /domains="nrpspksdomains_F0345_RS18290_TD.1"
                     /final_module
                     /locus_tags="F0345_RS18285"
                     /locus_tags="F0345_RS18290"
                     /monomer_pairings="Tyr -> Tyr"
                     /monomer_pairings="Tyr -> Tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       21879..21986
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F0345_RS18285_0007"
                     /evalue="4.10E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="F0345_RS18285"
                     /protein_end="662"
                     /protein_start="626"
                     /score="48.1"
                     /tool="antismash"
                     /translation="AYNETSALHITGPVDLSALRRAVQDLADRHEAFRSS"
     CDS_motif       22206..22268
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F0345_RS18285_0008"
                     /evalue="2.10E-04"
                     /label="C3_LCL_132-143"
                     /locus_tag="F0345_RS18285"
                     /protein_end="756"
                     /protein_start="735"
                     /score="14.0"
                     /tool="antismash"
                     /translation="HHTVADGLSQDVLDHDLAQCY"
     CDS_motif       22611..22700
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F0345_RS18285_0009"
                     /evalue="1.90E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="F0345_RS18285"
                     /protein_end="900"
                     /protein_start="870"
                     /score="45.9"
                     /tool="antismash"
                     /translation="DVLIGSPFSGRPSQEAEDVIGFFTNTVVMR"
     CDS_motif       22689..22748
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F0345_RS18285_0010"
                     /evalue="2.60E-01"
                     /label="C2_LCL_024-062"
                     /locus_tag="F0345_RS18285"
                     /protein_end="916"
                     /protein_start="896"
                     /score="3.8"
                     /tool="antismash"
                     /translation="VVMRVRLDGRLDPLPLLGAV"
     CDS_motif       22761..22868
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F0345_RS18285_0011"
                     /evalue="1.80E-05"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="F0345_RS18285"
                     /protein_end="956"
                     /protein_start="920"
                     /score="17.0"
                     /tool="antismash"
                     /translation="QEGLEHQYVAFNDVVRAVGARGGTSGQPLVQVVLAY"
     gene            23181..25898
                     /locus_tag="F0345_RS18290"
                     /old_locus_tag="F0345_18330"
     CDS             23181..25898
                     /NRPS_PKS="Domain: AMP-binding (11-386). E-value: 2.5e-68.
                     Score: 222.5. Matches aSDomain:
                     nrpspksdomains_F0345_RS18290_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (491-533). E-value: 1.9e-08.
                     Score: 26.5. Matches aSDomain:
                     nrpspksdomains_F0345_RS18290_PP-binding.1"
                     /NRPS_PKS="Domain: TD (601-812). E-value: 3e-18. Score:
                     57.9. Matches aSDomain: nrpspksdomains_F0345_RS18290_TD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012711.5"
                     /locus_tag="F0345_RS18290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18330"
                     /product="AMP-binding protein"
                     /protein_id="WP_100456686.1"
                     /sec_met_domain="AMP-binding (E-value: 2.9e-69, bitscore:
                     232.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.8e-06, bitscore:
                     26.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.4e-13, bitscore:
                     49.0, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLSTFLAHHLGARGAEPALESGTRTWSYADLDRITRDRAARLRG
                     LHPKAVRIALVGEHTAEALVWTLAVMRAGLVHTPLSPGLPPERMREALRVAGPDLVLRC
                     TTEPLREEDLGRPVIDAAQLAAGASLADGAESPVSWPVQETAYSIFTSGSSGLPKLVNV
                     GHQGVEALCEAQTRLFGVEPGDRVLQFSSLAFDASVAEVLVTLYAGGTLVVPVWDGGSW
                     VNAVGTHLAEHGCDVITAPPSVYARLTDEARKMIGTVVFAGEAMTEVDFRMAARFSRVF
                     NAYGPTEGTVCFSVAEPSRFTTSVGRPVDGYEARVHDPATHTYTTSGLGELVIVGQGVA
                     LGYEGVERGEAPFTTVDGARAYHTGDEVELRDGEVFYRGRIDDRIKRLGHRIALTELEG
                     RLSALLGSRVAVLTHEGSLVLAHTTTGRTEPELKAWLREVLPNWEVPDTLLLVPDIPVG
                     HTGKADKDALRALVGRDGTGTRSGGAGEEAGQDAVSALVEELLGVPVTPGTSFFDAGGD
                     SFGLVQLQVKLAQLYGEERVQSAFDLLNYDFTVEGFLAAVGDAPQAAASPVPAVLRTVS
                     SDLAGLTASLTALRQEASGAPGTVTVTGAGGFIGGHVLDKLLGTGRPLVVVTTSSPRRV
                     VERHCVRFGRQEADFSDVRFLSYDDLEAPAEDTGGWGAVVHCGYHVNHVLPLERQVKDS
                     IATTRTLVRAAAERGAHQFVFVSAASVGQEFVPLTEDALEAVGDPYSQSKFVAESYVGA
                     LDGTGCRVDIVRTGLVYGHQAGDAAFLDDDVFANLLRISGQRRVMPRLAGLVPVCHVAD
                     VVETLLTAAAGRAAERRAVLLQRTYDTDQLSAELGGVALADPREWLAAVTEAGATDPRV
                     LAALRLWLDEQGWSGPVHATCRPIIRELIKTLEI"
     aSDomain        23214..24338
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F0345_RS18290_AMP-binding.1"
                     /evalue="2.50E-68"
                     /label="F0345_RS18290_AMP-binding.1"
                     /locus_tag="F0345_RS18290"
                     /protein_end="386"
                     /protein_start="11"
                     /score="222.5"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="GARGAEPALESGTRTWSYADLDRITRDRAARLRGLHPKAVRIALV
                     GEHTAEALVWTLAVMRAGLVHTPLSPGLPPERMREALRVAGPDLVLRCTTEPLREEDLG
                     RPVIDAAQLAAGASLADGAESPVSWPVQETAYSIFTSGSSGLPKLVNVGHQGVEALCEA
                     QTRLFGVEPGDRVLQFSSLAFDASVAEVLVTLYAGGTLVVPVWDGGSWVNAVGTHLAEH
                     GCDVITAPPSVYARLTDEARKMIGTVVFAGEAMTEVDFRMAARFSRVFNAYGPTEGTVC
                     FSVAEPSRFTTSVGRPVDGYEARVHDPATHTYTTSGLGELVIVGQGVALGYEGVERGEA
                     PFTTVDGARAYHTGDEVELRDGEVFYRGRIDDRIK"
     CDS_motif       23616..23675
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F0345_RS18290_0001"
                     /evalue="2.30E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="F0345_RS18290"
                     /protein_end="165"
                     /protein_start="145"
                     /score="17.2"
                     /tool="antismash"
                     /translation="AYSIFTSGSSGLPKLVNVGH"
     CDS_motif       24309..24374
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F0345_RS18290_0002"
                     /evalue="2.40E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="F0345_RS18290"
                     /protein_end="398"
                     /protein_start="376"
                     /score="13.9"
                     /tool="antismash"
                     /translation="YRGRIDDRIKRLGHRIALTELE"
     aSDomain        24654..24779
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F0345_RS18290_PP-binding.1"
                     /evalue="1.90E-08"
                     /label="F0345_RS18290_PP-binding.1"
                     /locus_tag="F0345_RS18290"
                     /protein_end="533"
                     /protein_start="491"
                     /score="26.5"
                     /tool="antismash"
                     /translation="AVSALVEELLGVPVTPGTSFFDAGGDSFGLVQLQVKLAQLYG"
     aSDomain        24984..25616
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F0345_RS18290_TD.1"
                     /evalue="3.00E-18"
                     /label="F0345_RS18290_TD.1"
                     /locus_tag="F0345_RS18290"
                     /protein_end="812"
                     /protein_start="601"
                     /score="57.9"
                     /tool="antismash"
                     /translation="VTGAGGFIGGHVLDKLLGTGRPLVVVTTSSPRRVVERHCVRFGRQ
                     EADFSDVRFLSYDDLEAPAEDTGGWGAVVHCGYHVNHVLPLERQVKDSIATTRTLVRAA
                     AERGAHQFVFVSAASVGQEFVPLTEDALEAVGDPYSQSKFVAESYVGALDGTGCRVDIV
                     RTGLVYGHQAGDAAFLDDDVFANLLRISGQRRVMPRLAGLVPVCHVAD"
     gene            25902..26912
                     /locus_tag="F0345_RS18295"
                     /old_locus_tag="F0345_18335"
     CDS             25902..26912
                     /EC_number="2.1.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019846.5"
                     /locus_tag="F0345_RS18295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18335"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_100456685.1"
                     /transl_table=11
                     /translation="MTSDTAMTVVSEQRWDPGPPLDAGFVDGEISIREELRRGDFTRWR
                     RAGGHELRERLTDRPERLFLFQTEGHWYAGCKTISDYVLDQGMPGVFCSRVYWYNVVGT
                     VTSVRTSDTDARIVFEPLDETGRRAAFEAITPLTEIVHPFAKQRDPGREKTSPSDGWLV
                     TEERAAFLGLGEQHLRRYTRERFRSWCEAADGDLLAYDPACSTGQFLSEFATMDPARIR
                     TVGQDLSSQMADFAASRLERVVCGDAASPAVESGSVDILFSRFLNSEVVSTAQARSLLP
                     ALVDTLRPGGTMVLLGHSPVLLDAVDLVSAGLRVRQTVARQDDHLFQYYVCEHGA"
     misc_feature    26914..26926
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.41"
                     /tool="antismash"
     gene            26914..28518
                     /locus_tag="F0345_RS18300"
                     /old_locus_tag="F0345_18340"
     CDS             26914..28518
                     /EC_number="3.-.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015032127.1"
                     /locus_tag="F0345_RS18300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18340"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_100456683.1"
                     /transl_table=11
                     /translation="MTLSLKKNVIAEPAVAGWYAWSYLLPPQTLAKYLKNHYRNIVESY
                     LADPQTHRTALRNARFLGGPFVYEQDGSYDRIRKWYDTAREQYAPLLELADAIDELEQK
                     ILPEQTGASLDQVYRQLPAPLAGRVELFYNRDNRTPDYRFIEPFLYASPYFDTALQQVR
                     FSEVHQDARQFALTTPVLAYTPEQVLVTVPLESELLDTVFRGGLTEEELRRVIDGLGLD
                     GERAAAFKGFFAEDPEPADSPGHAEPGEDVLEYVGHACVFVRHRGTTFLVDPVISYSGY
                     GHESDGRFTFDDLPERIDYVMITHNHQDHMLLETLIKIRHRVGRVVIAKSANSSLVDPD
                     LKRILTGLGFRDIVELDDLDTLDTPGGSITAVPFLGEHGDIRIRTKCGWMLDLDGTRVL
                     FAADSTNVSPELYPQVTAALGQVHTVFIGMESVGAAVSWLYGPLFPEKLERRIDAGRRL
                     KGSNFAQAAEIVDALGADSVYVYAMGQEPWLGAVMCVEYDEKHPAMIDSDRLVAHVGER
                     GGTAKRLFLHETIAIRP"
     gene            28515..29786
                     /locus_tag="F0345_RS18305"
                     /old_locus_tag="F0345_18345"
     CDS             28515..29786
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F0345_RS18305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F0345_18345"
                     /product="acetyl-CoA carboxylase biotin carboxylase subunit
                     family protein"
                     /protein_id="WP_124287621.1"
                     /transl_table=11
                     /translation="MNAGKPHVVHIGFHASEAHTVDFEADHVTVVMPRASAARLPAALA
                     ARFARIEVLDLPDSDDLDTYDRAVDRMRELVEDLVAQFGPPAAIVGLYEHTTLPAARLR
                     EHFGVPGTGAKTALLCRDKVPMKEALSGTGIRVPRFLAVGPDTPRAELSEFARGLPGRV
                     VLKPRSQGASIGVRILDGAAELLALADAGGIEEGYEAEEFVDGSIYHIDGVVRDGEMRW
                     FCASRYLDTCFDFRHGTAPLGAVTPDSPGLVRRMRDVTGTVLEALGLTDSTYHMELFHT
                     PGDELVFLEIGNRFGGAGISWHQRQVYGVDLARESVLACLGRPSEVATPTTMLDHRDVG
                     ASGWLYMPAVSGAVRVVAVRGLDELPGSVVGVNTPSVGDVLDSEGLIWATAGGFLVRGD
                     STLAVERDMARIISTYTLETKAGD"
     gene            29786..30637
                     /locus_tag="F0345_RS18310"
                     /old_locus_tag="F0345_18350"
     CDS             29786..30637
                     /NRPS_PKS="Domain: TauD (9-276). E-value: 3e-54. Score:
                     176.5. Matches aSDomain:
                     nrpspksdomains_F0345_RS18310_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121: dioxygenase, TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.5"
                     /locus_tag="F0345_RS18310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18350"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_161499815.1"
                     /sec_met_domain="TauD (E-value: 2.9e-52, bitscore: 176.5,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARTRLGTHIGVVVDDYRLDPADPGLRDFVTELLLQHKVVFFKSQ
                     HLDRHTFMQVAKRIGRTEVHPFISEDEPVVHGISPFQPYHEYPEITGIYHDEEHTGNLN
                     AWHSDLNWREVPTFGSLLRAVQIPPRGGDTCWANMAAAYASLSSEVKEQLDGLRVVHDW
                     MQIYFPAFDGNDETLARMREKYPAQSHPLVLTHPFTGEKSLFSNKVSGVRVEGVDEAES
                     KRILDMVHLLAWRPEFQCRFSWEEGDVAIWDNLASQHYAVSDYWPHTRKMERITLEGES
                     IK"
     aSDomain        29813..30613
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F0345_RS18310_TauD.1"
                     /evalue="3.00E-54"
                     /label="F0345_RS18310_TauD.1"
                     /locus_tag="F0345_RS18310"
                     /protein_end="276"
                     /protein_start="9"
                     /score="176.5"
                     /tool="antismash"
                     /translation="IGVVVDDYRLDPADPGLRDFVTELLLQHKVVFFKSQHLDRHTFMQ
                     VAKRIGRTEVHPFISEDEPVVHGISPFQPYHEYPEITGIYHDEEHTGNLNAWHSDLNWR
                     EVPTFGSLLRAVQIPPRGGDTCWANMAAAYASLSSEVKEQLDGLRVVHDWMQIYFPAFD
                     GNDETLARMREKYPAQSHPLVLTHPFTGEKSLFSNKVSGVRVEGVDEAESKRILDMVHL
                     LAWRPEFQCRFSWEEGDVAIWDNLASQHYAVSDYWPHTRKMERIT"
     gene            30634..31167
                     /gene="cpt"
                     /locus_tag="F0345_RS18315"
                     /old_locus_tag="F0345_18355"
     CDS             30634..31167
                     /codon_start=1
                     /gene="cpt"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091418.1"
                     /locus_tag="F0345_RS18315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18355"
                     /product="chloramphenicol phosphotransferase CPT"
                     /protein_id="WP_100456678.1"
                     /transl_table=11
                     /translation="MSTQVIVLNGGSSSGKTGITRCLKAILPHPWINLGVDDLIDRLPP
                     SLVEAGSGVEFGQQGEVHLGDGFREMEEAWTKGVAAMARAGARIIIDDVFLSGAASQDR
                     LRAQLEGLEVLWVGVRCDAEIAAGRELARGDRVIGMAVSQAEIVHKGVTYDVEVDTSRT
                     ESLDCARTIAARVS"
     gene            31280..32506
                     /locus_tag="F0345_RS18320"
                     /old_locus_tag="F0345_18360"
     CDS             31280..32506
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.5"
                     /locus_tag="F0345_RS18320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18360"
                     /product="MFS transporter"
                     /protein_id="WP_164494974.1"
                     /transl_table=11
                     /translation="MSHPPGRPAAQKTWGKFWLLTSAASVSEMGNTFLHLAMPWTILAS
                     TGSALMAALSLGVQYLPFVASPLLGTLIDGYERRMVFMVSELVQGVLIALTPLLLMADQ
                     VELVLVVLLVAGCGTVTSNLTSDFSLLPMLAPENRLTEAYSRFGAVTELARTAGPAVAG
                     LVLAVVGGYGALWIDAATFLVTAVIAAFLPRGEKPVVERGFLRMQVEGFRSFRKIRGVP
                     RLTLVLSVYNLGAGAVPTIILVVAAGTWGWSSGLAGAVLAAGAAGSALGSWLGGRLWHN
                     ASAERRIRLWFLVCAVSSVGLLAPWEEVVVLGFCCLMAGEGGMNVTTNEYRFRAIPDEV
                     SGRVNAVMRAFILGGAALSSLLLGWSVTLPEQVLRFAPALITSVLAVLIWAGVRSFRAP
                     VGTEPEKAA"
     gene            32552..33115
                     /locus_tag="F0345_RS18325"
                     /old_locus_tag="F0345_18365"
     CDS             32552..33115
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F0345_RS18325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F0345_18365"
                     /product="hypothetical protein"
                     /protein_id="WP_206432843.1"
                     /transl_table=11
                     /translation="MLYMFAFDKVGIVVGDLYFVDPEPLKGQESAEHGVRLELRLVEQG
                     ALVDSVYAAYPITVDQPVWRADFLESVDGRPGSFDRTHHHPVFTGWDPGDRVFVRELSA
                     DPMGWLGDRLADLGGLLKTAGLPADTAGPADAAELRRAAPEIVDATRRLLDRVRAGEIG
                     NRPAGVPPEPVEGQFQALVRSGWL"
     gene            complement(33169..33963)
                     /locus_tag="F0345_RS18330"
                     /old_locus_tag="F0345_18370"
     CDS             complement(33169..33963)
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014841.5"
                     /locus_tag="F0345_RS18330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18370"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_202854059.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 1.7e-43, bitscore:
                     146.4, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIPPYGVGADLLSRFAELPRLRLLQLESAGVEWIRPYVPEGVVL
                     CNAKGAYDRAVTEWVTGVVLAHLLRLPRFEQARRDERWDYTHTDSLEGKRVLLVGYGSL
                     GSALAPVLAGFGAEVAAVARRARPGVHGVDELPGLLPEADIVVLLLPLTEATTGLVDAT
                     FLSRIRDGGLLVNAGRGRLVDTDALVAELRGGRLYAALDVTAPEPLPAGHPLWSAPGLI
                     LTPHTAGSNTSPPARAMALAKAQLARYAAGEPLANVVGEAGY"
     misc_feature    34082..34095
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.55"
                     /tool="antismash"
     gene            34516..35784
                     /locus_tag="F0345_RS18335"
                     /old_locus_tag="F0345_18375"
     CDS             34516..35784
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014805.5"
                     /locus_tag="F0345_RS18335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18375"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_100456672.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 6.1e-09, bitscore:
                     34.5, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 7.3e-07,
                     bitscore: 27.2, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLAVHSPYTDAREAPVLLLVGSGYRPYREYILAAVSQHYRLWL
                     LDSHEATWQLRYCAGATRVDTRDADAVREAALAVGESLRVVGVFTYDETQVVSCARLAQ
                     DLGLPGSPPEAITNCRDKAATRATLAAAGVPQPASVVVTTAEEALGAAERIGYPVIVKA
                     RGMAASFGVVRADDAADIAAAFAAADGADFMDLPRYPANVLVEEYLTGPEISVDAVIHD
                     GEVTPTVIAHKRLGLEPYFEETGHDVDARDPLFEDEELLRQLRDIHRALGLTHGATHSE
                     FKLTPRGPRLVEVNARLGGDLIPYLGLLATGVDPTVAAAHAAAGRRADLTPVHRKAAAV
                     RFLLPEGRCRTVEVVTHTDRFGPTVHETGITADPGDELDLPPAAFFTRYGHVVAVGEDM
                     GQVQEDLREPWRLLELRAEALPD"
     gene            35885..37231
                     /locus_tag="F0345_RS18340"
                     /old_locus_tag="F0345_18380"
     CDS             35885..37231
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (96-440). E-value:
                     2.7e-31. Score: 100.9. Matches aSDomain:
                     nrpspksdomains_F0345_RS18340_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321857.1"
                     /locus_tag="F0345_RS18340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18380"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_100456670.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.4e-29, bitscore:
                     101.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSVSEHLDTAPVPRAPVPGGVRLDAAELHASVSDPCLTAMTLLN
                     DIAGRHPDAVSFAAGRPYEGFYEVAALGDHLTAFERHLVDDLGLGPEDVRRTFFQYGRT
                     KGFIHHLIARHLASDERMTVDPESVLVTTGCQEAMVLVLRALCRDERDVVLAAYPTYVG
                     FLGATRLVDAQVRPVAEGPGGIDLADLAEQIRRARADGLRPRACYVVPDFANPGGVSIP
                     EADRRRLLELAEREDVLLLEDNPYSMFHGGEGRLPTLKSMDVGHRVVYFGSFAKTAFAG
                     ARVGYVVADQPMADGALFADELAKLKSMLTLNTSTVAQAVVGGFLLRNDCSVERATVRE
                     AQVYRDNLRAVLAGLEKHFGEDGALPGSGVSWNVPEGGMFVVVTLPMRADDVLLTRSAE
                     RFGVLWTPMYHFYAGEGGSHQIRLSFSALTPERIDVGIARLARLVADRA"
     aSDomain        36173..37204
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F0345_RS18340_Aminotran_1_2.1"
                     /evalue="2.70E-31"
                     /label="F0345_RS18340_Aminotran_1_2.1"
                     /locus_tag="F0345_RS18340"
                     /protein_end="440"
                     /protein_start="96"
                     /score="100.9"
                     /tool="antismash"
                     /translation="TFFQYGRTKGFIHHLIARHLASDERMTVDPESVLVTTGCQEAMVL
                     VLRALCRDERDVVLAAYPTYVGFLGATRLVDAQVRPVAEGPGGIDLADLAEQIRRARAD
                     GLRPRACYVVPDFANPGGVSIPEADRRRLLELAEREDVLLLEDNPYSMFHGGEGRLPTL
                     KSMDVGHRVVYFGSFAKTAFAGARVGYVVADQPMADGALFADELAKLKSMLTLNTSTVA
                     QAVVGGFLLRNDCSVERATVREAQVYRDNLRAVLAGLEKHFGEDGALPGSGVSWNVPEG
                     GMFVVVTLPMRADDVLLTRSAERFGVLWTPMYHFYAGEGGSHQIRLSFSALTPERIDVG
                     IARL"
     gene            37366..38931
                     /locus_tag="F0345_RS18345"
                     /old_locus_tag="F0345_18385"
     CDS             37366..38931
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092028.1"
                     /locus_tag="F0345_RS18345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18385"
                     /product="APC family permease"
                     /protein_id="WP_229831611.1"
                     /transl_table=11
                     /translation="MTATATGPDTRPEPGQDANLKRDLGYWSLTGVACGGIIGSGWLFG
                     SFYGAQAAGPAAVISWVIGGAALTLVALVLIELGAGRPEAGGMVRWPFIANGPLAGTLI
                     GWTMLLAVASTMAAQASAIVQYANRYLPGLYEDEALTLRGRFAGVGLLLVLVILNWFGV
                     RLFARLNLLVTAVKVLVPVLTIVALLVSSFHPGNISAGGGFAPYGWSASLTAIAGAGII
                     YAIDGFASPIELSAEAKNPRRDIPRAVLTAIGLAVLLNIVLQLTFVFAVPTESLGDGWR
                     GLTFASPFGELALLLNLSWLAAVVYADAVFSPGGSTYVAVAAGSRETYAVAKNEALPRW
                     FAGVSERSGVPRRAMALNFALSVVILLPSSGWRDLITVVGTLALLTYALCSVAAGTFRE
                     AAPERLAGWVRGLGWIAPAGFVVASELVHWSDWENLRIALPELLAAVLLFAVLRRRDLD
                     LRAELRTGAWLLGYLVWLLVMSGLGSFGGMNLIPAPWDTVAVALSALATYRWGVRSGVA
                     HLRR"
     gene            39140..39973
                     /locus_tag="F0345_RS18350"
                     /old_locus_tag="F0345_18390"
     CDS             39140..39973
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003957440.1"
                     /locus_tag="F0345_RS18350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18390"
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="WP_100456666.1"
                     /transl_table=11
                     /translation="MTHSPAGRLQGLFEGRRLTPTQRRIAHCMVRHADEVPFLSSVELA
                     ELAGVSQPSVTRFAVALGFDGYPALRRDLRERVPAAPAAAAEANGYQQAVEGEIANLRR
                     LADFLADPGPLERAGRLLAGSRPLPVLGLRAAAAQARGFAYFAAKVHPDVRLLDEGGTM
                     LVDRIDAARLAGASALLCFALPRHPREVVEALAYARERGLRVVTVADSAFAPVAAESDV
                     LVPGAVGTGLAFDTACAPMLLGRVLLEAMCDALPDAQARLERFDARAADRGLFAE"
     misc_feature    39979..39997
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.87"
                     /tool="antismash"
     gene            40110..40649
                     /locus_tag="F0345_RS18355"
                     /old_locus_tag="F0345_18395"
     CDS             40110..40649
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018895297.1"
                     /locus_tag="F0345_RS18355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18395"
                     /product="hypothetical protein"
                     /protein_id="WP_100456664.1"
                     /transl_table=11
                     /translation="MAVVQRAGAAPLWWLGVVAAGAGLVPDGLTGRRIGVLAGALLFLS
                     AAALVTLVRGGRAAALAEHAVRAARSDVLQARSVTVRNWRRGHAWWLALAFAAALGSAF
                     ALPAAGGMLLAGWGTGLWLRARRTGRVEESHDALLWTTADALGRGGGDPLGAKATRLRT
                     TGSRAGDATPGGGRRR"
     gene            complement(40683..41057)
                     /locus_tag="F0345_RS18360"
                     /old_locus_tag="F0345_18400"
     CDS             complement(40683..41057)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008417686.1"
                     /locus_tag="F0345_RS18360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18400"
                     /product="hypothetical protein"
                     /protein_id="WP_100456662.1"
                     /transl_table=11
                     /translation="MANTETSLKEAMSVIEGATGVALVDYTSGMALGTLGGGKDFNLEV
                     AAAGNTDVVRAKLRTMEHLGLKEEIEDILITLGGQYHLIRLLKSRGGNGLFLYLVLDAG
                     RANLAMARHQLRRIESELEV"
     gene            complement(41168..41677)
                     /locus_tag="F0345_RS18365"
                     /old_locus_tag="F0345_18405"
     CDS             complement(41168..41677)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008417684.1"
                     /locus_tag="F0345_RS18365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18405"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_100456660.1"
                     /transl_table=11
                     /translation="MAAEREVLDELQRLRARVPLLSGALAASADGLVLAQDTAGTEAES
                     LAALTAAALGVAVRLTDATGRGSFRELLVRGEQGYVATYAAGSSAVLTLLAEDRINVGR
                     LHLEGRRAGARIGALVDAALDRAATPQPPAEYPRVRPPARPVAPPPPPPAGASPGTPGS
                     LPRRPV"
     gene            complement(41716..42519)
                     /locus_tag="F0345_RS18370"
                     /old_locus_tag="F0345_18410"
     CDS             complement(41716..42519)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524738.1"
                     /locus_tag="F0345_RS18370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18410"
                     /product="hypothetical protein"
                     /protein_id="WP_100456658.1"
                     /transl_table=11
                     /translation="MTSAGSSTAALPPLSPMLRRLADERATGALMRDRGTLYLADGQVV
                     HAESPATPGIDVLLTAGGTLARAGWWEAVAAAGARQRVAAYLVDSGRVPGGALELCHLG
                     ALYDAAFFALAPTSTPARFRYGVSHWIGPVHPVPARSVERETLRRRELLDRIWPDAAVD
                     TAPLARLTDGADLPLTPRRRAVLEAVDGTRTAAAIALGLGRSAFHTLIDVRRLAAAGAL
                     DAVRSYGRPEDASPGAHAGAPVLPEVTPDPDIALLRRLRDALEVL"
     misc_feature    complement(42487..42489)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(42516..42926)
                     /locus_tag="F0345_RS18375"
                     /old_locus_tag="F0345_18415"
     CDS             complement(42516..42926)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950375.1"
                     /locus_tag="F0345_RS18375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18415"
                     /product="hypothetical protein"
                     /protein_id="WP_100456656.1"
                     /transl_table=11
                     /translation="MPGIDECLLDIMKLPGARGAAVVDWTSGLALGTIGESPHDDHEAT
                     AAETAEVARMAAEQPAFAQDSVRAAASPEGAADGGVEDVIVTSRAGYHILRFVETDFDS
                     SVFVHLWLHRSEGNLALARIRLGELADRLVLA"
     misc_feature    complement(42898..42913)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.51"
                     /tool="antismash"
     gene            complement(43438..44454)
                     /locus_tag="F0345_RS18380"
                     /old_locus_tag="F0345_18420"
     CDS             complement(43438..44454)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950376.1"
                     /locus_tag="F0345_RS18380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_18420"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_100456654.1"
                     /transl_table=11
                     /translation="MGSRQRPTIKTVAARAGVGRTTVSRVINGSELVSDEARSAVLAAI
                     AELNYVPNSVARGLVTSRTDSVALVIPESESRLGSEPYFSAVIRGVSTGLTERRIQLQL
                     VLVRDQAERDQLTESVAERRVDGVLLVSVHEHDPLPGLLENMGLPTVLAGRRAHGEPLS
                     HVRADNEGGAAAAVAHLVARGRRRVATISGPLDMDVSRSRLDGWRDALRGEGVEAAETL
                     VASADFTEAGGEAAMRSLLEREPGLDAVFAASDVMAAGALVELRRQGRRVPDDVAVIGF
                     DDSVVARHSNPPLTSVRQPVEAIGRTMARILLAEIDDPGQPRQHVVLPTELVVRESS"
ORIGIN
        1 tgaggccgct cagcccctgc tcgatctgct tggcctgctc ctccgcgagc tcctggccgg
       61 tgttggccgt cgcctcctcg ggcaccagcg cctggacctg cttcagcagt tcggcgtcgg
      121 aggcaccgga ggccgcggcg accgtcacgt cctggaagta gccggggcgc aggtactgct
      181 cctgggcggt gcgctggtcg aacaggacga ggctgccgcc ggcgttgacc gcgccgtcct
      241 cggtggtgaa gacaccggag agggtcagct cctggacggg cccgttggtg gcgacgcgga
      301 ccttgtcgcc gacctggtac tcgcccttct cggcggtggc ccggtcgagc gcgacctgcc
      361 cggccttcgg gccggagccg tcggtgaagg tgtactgcgg gtccttgccg tcggcgccgg
      421 gggagaagtt ggcaccggtg ttggaccagc cgctgcctat cagcttgccg tccgggtcgg
      481 cgacgcccgc gaagccggag acccggccgt gcgccgcgga gacaccgtcg agccggtcga
      541 tcctcttcag cgtcgcggcg tcgatgccgc tcttctcctg gtcgcgcggg tgcgcgtagg
      601 tctggacgga gacggcgacg tcgtcgtagc tcttcgccga ctggttgcgc agggcgttgc
      661 cgagggtgtc ggtgaagacc agggtgccgg agacgaaggc cacgccgagc atcacggcga
      721 gcacggtcat cagcagcctg gccttgtgcg caaggacatt gcgcagggcg gtacggaaca
      781 tgaggagtcc tgggaaggaa cgggcgggcc cggtgggccg cgcggggcgg agagaagcct
      841 gcgagcgggg tcgggctagc tggtgcggcc cttcgcgtcg aactccttca tccggtccag
      901 cacgctgtcg gccgtcgggc ggtgcatctc gtcgacgatg cggccgtcgg cgaggaagac
      961 cacgcggtcc gcgtaggagg cggcgaccgc gtcgtgggtc accatcacca cggtctggtt
     1021 catggcgcgc accgagttgc gcaggaagcc cagcacctcg gcgccggagc gggagtccag
     1081 attgcccgtc ggctcgtcac cgaagatgat ctccggccgc gaggcgagcg cccgggccac
     1141 ggcgacgcgc tgctgctgcc caccggagag ctgcgccgga cggtgcttga gccggtcgcg
     1201 gaggcccacc atgtcgatga cctggtccag ccagccctgg tccggcttgc ggccggcgat
     1261 gtccatcgga agggtgatgt tctccagggc ggtgagtgtc ggcagcaggt tgaacgcctg
     1321 gaagatgaag ccgatcttgt cccgccgcaa ctgcgtgagc tgcttgtcct tcagcgcgcc
     1381 gagctccgtg tcgccgatcc gcaccgagcc gccgtcgaag gtgtccagcc cggccacgca
     1441 gtgcatcagc gtggacttgc cggagcccga ggggcccatg atcgcggtca gctcgccctg
     1501 ccggaagtcg atggagacct ggtccagcgc gaccacccgg gtctcgcccg tgccgtacac
     1561 cttgctgagt tcggtggcgc gggcggccac ctcggtggac ctggaggcca gaggggtggt
     1621 ggtcacgggg aagctcctgt cggtggggcg ggggactcgg actgcgtcgt ccgccggcgg
     1681 gcggacgcgg caagccaccc ctgtccggtg gcggggtgag agtcgtctgt acggtctgcg
     1741 tccatccttc ctgccggaac cgcgcggacc atcactcccc agttcccttt cgagtgccac
     1801 tccgtggggt gaccggggga gcgcccgtca tacctgggta ggaccccccg cccgtaccga
     1861 ccctgaccgc cacccctgag acggggtgcc ctggaggccc gcctgccccc ggaaggcgtc
     1921 cggaaggcac ccggaaggcg ctcgtggcgg gagaccctgg tcacgctttc cggtggttcc
     1981 ggcgggccgc cccgcgcccc ggcggcgggg gacgccgaca ggccggcggg aggcgcggcg
     2041 gcccaacccg caaccggcgc aatgatcttc gcccggcccc tggtcgcatt ccggtcattc
     2101 ttgccccgag ccgtccatgg ccgggttcgg gtggagcctg ccgaagggcg gcgtggagcg
     2161 agcgcgcgct gtcctgatga cccctcaggc gccaataaaa taagacaaca tcggcttgag
     2221 ggcccgctgt ccgagtgact tgtccggata ggctcacacc gcgtatgcgg ccccccagct
     2281 tgcccggatg gtggaatgca gacacggcga gcttaaacct cgctgccctt cacgggcgta
     2341 ccggttcaag tccggttccg ggcacttcgg cccctccgcg cccggcgcgg catctcctcc
     2401 accaccccgc tcctcgcgtc ccctcactgc tgggtgtacc gccacgtgcg cccggccggc
     2461 tcgtgcttgg cgggcgcgta caggtcgcgg tcggccgggg tggcgcgcgg gtgggtcgcg
     2521 gaagcggagc gtacgggcgg tctcggggag gacgcgcagg tcgacggcgc tcgccgccgg
     2581 ggtgggtggg tgcgccccgg agcaggcggt gctcgttccg gtcgggtcgg cggatggtcg
     2641 ggcgcgggcc gagccgggcc agggccgggg ccgggacgta ggcgtcctcg tcggccgggc
     2701 cggggacggt cagggggagg tccggggcgg gcttggccgg cagggccggg atcgagggcg
     2761 ggccggcgtg ctcgacgtgg tgcgggagcc cggccggccg cgcgccgatc cgggccgcct
     2821 cggcggcgca cgcctaccgg cacggtgcgt accgcacgag ggcgaccggc ccgtcgagcc
     2881 ggggcgcggc tcgacgtacg cggcctcgac ctcctcgccg gccgtcgggt cgtggtcccg
     2941 gaggcggcgg agggcgcctg gtcgggcacg tgctgctcct ggcggacgcg ggcgggagct
     3001 gtgccgcgcc gctccccctc gcggtcgcct tcccgccacg cctccgggcg tggactttgc
     3061 ccgttcttgg tgctgctgcg ggaaaacgct ggaagagatg tagtactcct gctacgttcc
     3121 atcgcaggaa caagacggaa gacgggtcgt gagggcggac gggggagcgg gcgatggtgt
     3181 tcggcagcgg gggcgcggga ggcggcgggg acgccgtcgt cgacgtgcgg gacctgtgga
     3241 tgaggtacgg ggagaaggac gtgctgcgcg ggatctcctt cgagatccgg cggggcgagg
     3301 tgctgggact gctcgggccc aacggtgccg gcaagaccac caccatcgag atcctggagg
     3361 ggttccggca gccctcctcc ggacacgtgc gggtgctcgg cgtggacccg ctgaagggtg
     3421 acgacgcctg gcgggcgcgg gtcggcgtgg tgctccagtc ctggcgcgac cacagccgct
     3481 ggcgggtcgg cgcgctgctg gagcagttcg cctcctacta ccggccgtac accgggcgcg
     3541 acgggtaccc ggggccgtac gaggtggccg agctgctggc gcgggtcggg ctgtccgaca
     3601 aggcggagac caaggccggg gcgctctccg gcggccagcg gcggcggctc gacgtggccg
     3661 tgggcatcgt cggacggccc agcctgctct tcctcgacga gccgaccacc ggcttcgacc
     3721 ccaaggcgcg tggcgacttc cacgacctgg tgcacgccct ctcggacctg gaggacacca
     3781 cggtcctgct caccacccac gacctcgccg aggcggagaa gctcgccgac cgcatcctca
     3841 tcctcgacgg tggcggaatc gtcgccgacg gcagctcgga gcagctggcc cggcaggtcg
     3901 cgggcgagga cgaggtccgc tggacgcggc acggcgtgcg cgaggtccac ctgacaccgg
     3961 acggcacacg gttcacccgc gagctgttcg agcggcacgg cgaggaggtc accgaactgg
     4021 aggtgcgccg ggccagtctg gaggacacct acctgcggat ggtcgcgcag agcgaggcgg
     4081 aggcgggagc gccgggctcc gtccccggcg aggcggagcc ggctccgggc acggggccgg
     4141 ccagggaacg gacgggggaa ccggcatgag tgaggcagtg agcggtgcgg gcgagcggga
     4201 gcgggaggcc gcccggttcg cgtggggcca cggctacggc cccggggtcc ggcgcggcgc
     4261 cacggagttc ctgaactccc tgcgcacccc ggcggacgtg ggctactaca tcgtcggctc
     4321 ggccgtcttc ctcgtcgtca tgttcctcaa ccgccacagc gtcgacgaga cgaccggggt
     4381 cagcgcggga gcgctcatgc tccccggggt gctgggcttc acgatcatct tcggcgcgct
     4441 cttcgggctg gccaccgccg tctccaccga gcgggaggac ggcaccctgc tgcgcgccaa
     4501 gtcgctcccg cacggcacca cgggctacgt cgtggggcag agcacccggg ccgcgctgga
     4561 ggtcgtcctc tccctcgtcc tgctgctggt gcccggcctg atcctgctcg acaacgcctg
     4621 gtcgggtggt gtgtgggggg ttccgcacgc ggcctcgctg gtgctgctgg gcgtgctcgc
     4681 ctcgaccccg ctcggcttcg ccgtcggctc gctggtcaag aacccccgtg cactgggagg
     4741 ctgggggttc atgctgatga gcggcctggt cgggatctcc ggtacctttt tcccgctgtc
     4801 ggtgctgccc ggctgggtgg ccgggctcgc gcaggtcttc cccctctact ggctggggca
     4861 cggcctgcgg tcggcgatgc tgccggacgc cgcggcggcc ggagagatca acggaagctg
     4921 gcaggtgtgg gagagctacg cggtcctcgg ggcctgggcc ctgctcggcc tggtcctggc
     4981 gccggtgctg ctgcgccgga tggcccgcag ggagtcgggc gcctcgatgt ccgcccggcg
     5041 ggagacggcg ctccagcggt actgaggagc cgtggatgac gccccgtacg gagggggccg
     5101 ggccgggcgc gggcgccggg ccggacccgg tccacaaccg catcgcgatg ctccgcgtcg
     5161 aacgccacgt cacgcgccgc cagctcgccg acgccctcgg cgtccactac cagaccatcg
     5221 gctacctgga acgcggcgag tacagcccca gcctgcacct cgcgctgcgc atcgccgcct
     5281 acttcggcgt accggtggag ttcgtgttct ccctgacgcc gttcgccccg ctgaagccgt
     5341 agcgggtacg gtccggtgcc gggcgtgcgc cacccgtccg gggacattcc cgtacgccgt
     5401 gaggcgaacg tcacgcggtg ggccccggcc cggcgtcacc gccgcgatcc ccggcgcgac
     5461 gcggcgccgg cccggccgcg cgcaccccgt cccgcctgcg cggacggtcc tcgtacgggg
     5521 gtgcggcgag ttgtcccgga gagcccgcta tgggggtttg cccccggagg aaatcggtca
     5581 agagcgggga aagatccttc ccgagcagta gggtcattct tttgcccacg cattactctt
     5641 gggccaaggc cacgcagggt ggccacggag gagtgagatg aggagcagca acccggtctt
     5701 ctcgcgacgg gggttcagcc gcgacaacgg ccacgcgcag ttcaacgcgg cgccgcaggc
     5761 cgggggcccc gccgtaggaa cgcagcaggg caacccgtac gcgggcggca acccctacgc
     5821 gggacagaac ccgtacgccg gtcagaaccc gtacgcccag ggcgaccagc agacgtacgc
     5881 caacccgtac gcgcaggacc agtacggcgt ccaggcgccc accaccgacc gcatgacgat
     5941 ggacgacgtc gtcatgcgca cggcgacgac cctcggcacg ctgatcgtca cggccgccct
     6001 cgcctggtgg ttcctgccgg tcgacgcggc caacatgggc aagtcgtacg gcatcgccgt
     6061 cggcgccggt ctcgtcgcga tggtgctggc gctcgtccag tcgttcaagc gcaaggcctc
     6121 gcccgcgctg atcctggcgt acgccgccct cgagggcgtc ttcctcggcg tcgtgagcaa
     6181 cgtcgtcgac acgcacatcg ccaatggcgc ggccatgcag gccgtcatcg gcaccatggc
     6241 ggtcttcacc gcggtgctgg tggcctacaa ggccggctgg atccgcgtca accgccgctt
     6301 ctacggcttc gtgatggccg ccgcgatggg cttcgtgctc ctcatggcgg tcaacctgct
     6361 cttcgccgtc ttcggcggcg gtgacggcct cggcttccgc agcggtggcc tcggcatcat
     6421 cttcggcatc atcggcgtcc tgctcggcgc ctgcttcctc gccctcgact tcaagcaggt
     6481 cgaggacggc atcgcctacg gcgcgccgcg cgaggagtcc tggctggccg ccttcggcct
     6541 gaccatgacg ctggtctgga tctacatgga gttcctgcgc ctgatcgcca tcctccaggg
     6601 tgacgactga cggcaggtcc ccgcacgacg aagcgccccg cggagcatcc gcggggcgct
     6661 tcgtcgttcc cgggccaggg catagggtcg gcggtgtgct tgatacgacc ccgctgacca
     6721 gcgccgtgga ccagttcgcc gaccggcttc gggccgcccc gcagagcaag ctccagcgcg
     6781 gcgccgccgc cgaggccctg gaactggccc gggaactctc cgcccgcgcc cagcgcctgg
     6841 agcagcccgc cggggaggtg cgtgtgatgc ccgacgccgg gatgttcgcc gtcgccgacc
     6901 aggtgaccgt cgccgcccac gacctggccc tcgtcctgcc cggcaaggag gccctggacg
     6961 cggcggtggc ccgggtcgcc gaggcccggg agcgggccgg gatctgacgg ggcgtacgcg
     7021 cccgcgcggc gtaccggcgc cagacgcgcg aggtccgcgc cccggacggg acgcggacct
     7081 ggcggcggga gggcccgtct tcggacgggt ggaggtcaga cggaggctat gacgcggtcg
     7141 gccagcaggt agacgttgtc ctcaccgcag gagaaggtca gcgcgtacgc gcccgacacc
     7201 ccggagccgc ccagcagcac cggcgcctca ccggcccgca gcgaacccgc cagcagttcg
     7261 gccgtctccc ggtggcccgg ggtcatgcag agggtggtgc cgtcggcgaa cacgtagacg
     7321 tccagggtgc ccagcgggcc cgggcgcacg tcggcaaggg ccgtacggga ctgtgccagc
     7381 tcctccagca ccgccaccgt cgtctcgtgg tcgtcaccgg cgccctcgcg ctccaccggg
     7441 gtggggcgga ccgggacgaa gtccgggtgc gaggggtggc ggcggcgggc ggcggccagc
     7501 tcgggggagt cctcctccgg ctcgccggcc ggcttctgcg acgccgcctc ggcggcgtcc
     7561 agcgcgtcca gtcctgccag gtccgcctgg cgcgggatga acaggtcgtc caccagcccg
     7621 tgcaggccac ccaggagcga gggcgcgtcc gaggcgtccc gcgcctcctg cgccgcccag
     7681 aacgcccgcg cctcggccag ctcacgctcg cgctcctcgg cgagcgcctc cgcgacggcc
     7741 tcgcggatgc cctcggcgtc ggcccgcgcg gccgggacgg tggcccggcc ggggcgggtg
     7801 gcgtgcagct cggcgcggag cgccgtgatc tgccggcgga gcccgtgcac ggcgtgcagg
     7861 gcgacggctc ccacggccac cacggcggcg agggcgatca gcagggcaag ggtcatggcg
     7921 ctcactgacg tactcccggt tcgagtcggt ccccgacttc ctacatcagc ttgaagggcg
     7981 aaccatccgg ctgtcagtgc attacgtcac gaaagggaca ggtctttcgg tgggtcgttc
     8041 cccctcgacc catagtgacc tgcgaaaacg ccgatccccc gggatatagg tcacatcctg
     8101 ggggagattg ggtcacggaa cggaggaggg gtgagcgggg cggagggggg ccttcgcgcc
     8161 cctcccctcc ccacctgcga agggtggccc ggcgtgcgcg cggggccacc cttcgtgggt
     8221 tccgtgccag gtcagctcag gcgctcgatg accatggcca tgccctggcc gccaccgacg
     8281 cacatggtct ccagaccgaa ctgcttgtcg tggaactgga ggctgttgat gagggtggtg
     8341 gtgatgcggg cgccggtcat gccgaagggg tggccgacgg cgatggcgcc gccgttgacg
     8401 ttgaccttct ccagcggcag gccgaggtcg cggtaggagg ggatgacctg ggcggcgaac
     8461 gcctcgttga tctcggcgag gtcgatgtcg tcgatgctca gcccggcccg gcgcagggcc
     8521 tggttgctcg cctcgaccgg gccgtaaccc atgatctcgg gggagaggcc ggagacgccg
     8581 gtggagacga tgcgggccag cggggtcagg cccagttcgc gcgccttggt gtcggacatg
     8641 atcaccaggg cggcggcgcc gtcgttgagc gggcagcagt tgcccgcggt gacgcggccg
     8701 tcggggcgga agacgggctt caggccctgc acgccctcca gggtgacgcc ggcgcgcggg
     8761 ccgtcgtcct ggctcaccac ggtgccgtcc ggggtggtga ccggggtgat ctcgcgctcc
     8821 cagaagccct tctcgatggc ctcctcggcg aggttctgcg agcggacgcc gaactcgtcc
     8881 atctcctcac gcgtgacgcc cttcagccgg gccaggttct ccgcggtctg gcccatcgcg
     8941 atgtacgcgt cgggcagctt gccgtcctcg cgcgggtcgt gccaggagtc cgcgccctgc
     9001 tcggcgacgg cggccgtgcg ggcctccgcc tcggcgaaga ccgggttccg ggtgtccggc
     9061 agggagtcgg agttgccctt ggcgaaacgg gagaccgtct cgacaccggc cgagatgaag
     9121 acgtcgccct cgccggcctt gatggcgtgc agggccatgc ggctggtctg gagggaggag
     9181 gagcagtagc gggtcaccgt gcagccgggc aggtggtcca tgcccatctg gacggcgatg
     9241 atccggccga ggttgttgcc ctgctcgccg ccgggcaggc cgcagccgag catcaggtcg
     9301 tcgatgtcac gagggttcag ctcggggacc ttggccaggg ccgtctcgat gatgtgggcg
     9361 gtcaggtcgt ccgggcgtac gtccttcagg gagcccttga aggcgcggcc gatgggggag
     9421 cgggcggcag agacgatcac ggcttcgggc atcgggcggc tccagtcggt aggggggcgg
     9481 ggcttctcct gcggaagcta cccgtacgta acgtgcgggt cacccactgg gggctgtgac
     9541 acgggccgca ctttctaagc gcttgctcat gggtgtgtgg ctcgaccgga gggacggggg
     9601 ccgagccgtc ctggggtggg gcggtgctcc ggtgccgccg cccggcgtcc ccaggcaccg
     9661 gccgggccgg gtggtcccgg acgccggccg ggccgggagc gccgaggtga tgctcggcat
     9721 cgtgaaccgg tgctcctgag ccggtccgta ccggaactca gcccggccgg cgatcgaggc
     9781 cgcccccctc ggccgccggg gcccccgtgg ccggagcggg ggagggctcg tgggtgatgc
     9841 gccggcgccg gcgccgcttg aggagggcga gaggcccccg cgcgcccccg gccgcggcca
     9901 cctcggtgcc gccctcggag gcggcccgag cggcggcgcg ggccaccggc aggaacccct
     9961 cgtcccgagc ggcctccggc cgctccccct cgggccacag gccgagcgag gcgcagagcg
    10021 tgggcagcac cgccatcgcc gccgtcgcgt acccctccgc cgaggggtgg tagttgtccg
    10081 gcccgaacag ctcccgcggg ttctgcgcga actcgggccc cagcaggtcc ccgagcgaca
    10141 cggtccgccc gccctgctcc accgtcccga tcgtctgcgc ggccgccagt tgccgtgagg
    10201 cccgccgggc cagccagcgc agcggctggt agacgggttc gatggtgccg aggtcggggc
    10261 aggtcccgac caccacctcg gccccggccg tccgcagccg ccgtaccgcg gaggcgagca
    10321 gccgtaccga ctcggtggcg gtcatgcggt gggtgacgtc gttggcgccg accatcagca
    10381 cgcagacgtc cgggacccag ccgccgtcgg ccagcgccag cgagacctgc cggtcgaggt
    10441 cgtcggagcg ggcgccgggc accgcgacgt tccgcagctc caccgggcgc tccgcgacgg
    10501 ccgccaggcc gctggcgagc agcgccgccg gggtctgccg ggaacggtgc accccctgcc
    10561 cggcggcggt cgagtcgccc agcatgagga accgcagcgg ctccacctcc ggcccgtcct
    10621 cgggccggac gccgaacgcc cttccgtaca ccccgtcggc gcgcggcggc gcggcgccgt
    10681 ccccctggct ccccacggaa cgcttggcca actgcgcctc ggccagcagc acgccgacac
    10741 cggccacgcc cagcagcccg atgccgccac cgccgtacgc cgcgcccgcc gcgatccgcc
    10801 gtgccaccct cgccctcgac atgaccggca gccacctcct cgtagccgta cacccacact
    10861 gtgccccgcc gggcaggtcc gccaatcccc gacggccacg cgcgaggccc cgggcggctt
    10921 acgctgtgcc cacccataca gccctgcgtt acgcagttca tcgacgcccg gagacaacgg
    10981 tgcacatcca cgactcgatg gtcgacctgg tcggcaacac cccgctggtc aggctcaaca
    11041 acgtgaccga gggaatccag gcgacggtcc tggccaaggt cgagtacttc aaccccggcg
    11101 gctccgtgaa ggaccgcatc gccctgcgca tgatcgagga cgccgaggag cgcggcctgc
    11161 tcggccccgg ctccacgatc gtcgagccga ccagcggcaa caccggcgtc ggcctcgcca
    11221 tcgtcgcgca gcagaagggg tacaagtgcg tcttcgtctg ccccgacaag gtctcgctgg
    11281 acaagatcaa cgttctgcgg gcgtacggcg ccgaggtcgt ggtctgcccc accgcggtcg
    11341 accctgacca cccggactcg tactacaacg tctccgaccg gctggtccgg gagacgccgg
    11401 gggcgtggaa gcccgaccag tactccaacc cgaacaaccc cctctcccac taccactcga
    11461 ccggccccga actgtgggag cagacggacg ggaagatcac ccacttcgtc gcgggcatcg
    11521 gcaccggtgg caccatctcc ggcaccggcc gttacctcaa ggaggccggc gacggtggtg
    11581 tgcaggtggt cggcgcggac cccgagggct cggtctactc cggcggctcg ggccgtccgt
    11641 acctggtcga gggcgtcggt gaggacttct ggccgaccgc ctacgaccgg aacatcaccg
    11701 accggatcgt cgcggtctcc gacaaggact ccttccagat gacccgccgc ctcgccaagg
    11761 aggagggcct gctggtcggc ggctcctgcg ggatggccgt cgtcgccgcc ctggaggtcg
    11821 cccgggagct cggccccgac gacgtggtcg tcgtgctgct gcccgacagc ggccgcggct
    11881 acctctcgaa gatcttcagc gacgagtgga tgaacgacta cggcttcctc gaccagggcg
    11941 gcgacgagcc gcgcgtcggc gacgtgctgc gcgacaagga gggcgacatg ccccacctcg
    12001 tccacatgca ccccgaggag accgtcggtg aggccatcga ggtgctgcgc gagtacggcg
    12061 tctcccagat gccgatcgtc aagccgggcg ccggccaccc cgacgtgatg gccgccgagg
    12121 tcgtcggctc cgtcgtcgag cgggaactgc tcgacgccct cttcgccagc cgggcggccc
    12181 tggacgaccc gctggagaag cacatgtcgc gcccgctgcc gcaggtcggc tccggcgagc
    12241 cggtcgccga cctgatggcc gtcctcggcc aggcggacgc cgcgatcgtg ctggtggagg
    12301 ggaagccgac cggcgtcgtc agccgccagg acctgctctc cttcctcgcc cgctcggccg
    12361 gcaccgccgt caagtgaccg accgcgcggc ccgcgccccg gacgcccggg ggcgggccgc
    12421 gctccccttc gcgcaagtgg tacgagcccg acacgtcggc gcagcacccg gttaacacgc
    12481 atcgggcaca ttggtgggtg tcggcagggg acggcacacg accaccggga gaaccggggg
    12541 cgatgtgccg ctcaccaccg gcacgcgaac ggcgtcacgg acctccggag cggctcccgg
    12601 acctccgaac gacgcccgcg ggcgcggcgc ccggccctga cccggcgccc gcccctcgcg
    12661 gggaccgccg tcgtcccgcc ctcctgggcc cggcccgggg ggtgcggcgg tccccgcgca
    12721 ccccccccgt ccgaggcccg agggcgggcg gaactggcgg agcggcttcg ccgcctgctc
    12781 gaccgccccg gccggaggtg acgcggcgtc accacgcgcg ggaccgcgga gacctctgcg
    12841 ccgatcaact tcaggacggg aaattcccgc gcagtgactc aacagttctc ggcggcgccg
    12901 aaagcctttt aggaaagggt tgtcgcgcca tgccggaggg tcctatgctg actcggccga
    12961 tgatgctgtg acggggcgtt catgtcgacc ccgaagaaaa ggcgatacgc cccgctcctg
    13021 ttcgaaaggc atgtttcgtg cgcaccaccg aactcggtga tggaggtccg gccgtcggcc
    13081 ggataggact gggcgcgatg ggaatgtcct tcgcctatga tccgcgacac cgcgatgacg
    13141 gcacctccat caccgtcatc cgtcgcgcgc tcgatctggg cgtcaatctg atcgacacgg
    13201 cggatgtgta cgggccgttc gccaacgagg aactcgtcgg gcgcgctctg atcggccggc
    13261 gtcacgaggc cgtgctgtcg agcaagggcg gtgtccggtt cgacggggcg gaggtcaccc
    13321 tcgacggacg cccggagtac ctcaggtcgg ccctggaggc cagcctgcgg cgtctgcgca
    13381 ccgaccacct cgacctctac ttcctgcacc gtgtcgaccc gcgagtcccg gtggaggaga
    13441 gctggggcga gctcgcggac ctcgtggccg agggcaaggt gcgcgccctc ggtgtctccg
    13501 aggcgtccgc ggacgaggtc cgcagggcag gtgcggtaca cccggttgcc gccgtccaat
    13561 cggagttctc cctgttcacg cgggatttcc aggacgacgt cgtgcccttg tgccgcgagc
    13621 accgcatcgc gttcctgtgc cactcaccgc tcggcagcgg acttctgagc gggcgctaca
    13681 ggacccgcgg ggacctcacc gaaggcgatg accgggccga catgccccgg ttcaccgagg
    13741 aggcgatggc ggccaacgcc gggctggtgg accgggtcgg ggcggtgggc cggcgtcgtg
    13801 gcgccacctc tgcccaggtc gccctcgcct ggctgctcgc ccagggcgag cacgtgatcc
    13861 cgatcccggg caccaagact ccgcgctacc tggagcagaa cgtcgcggcg gccgaactgg
    13921 tcctgtccgc ggaggacctt gacgagttgg acgcgctgcc ggcgccgacg ggcgcccgcg
    13981 aatagcgggg ttccggtact cggtcctgcc gcacccacca catgattggg gccacatgga
    14041 aagattcgcc atcttcgatc tcgacgatac gctggtggac agcaccggag cggtggaccg
    14101 gtggttcatc gaagtctccg aacagcggaa cctcggtgcg gccgggctcg aattcctccg
    14161 ggcggaacag gagcgtccgg tatcccctcg ggaatctttt caggccatca tcgacagatt
    14221 cggcttcacc gaatcaccgg atgaactccg cagcatattc ctggaccgcg taccacgtct
    14281 ttcccgcacg ttcgacggcg tactggagaa cctcgcggaa ctgcgggcgc gcgggtggcg
    14341 gacggccctt ctgacgaacg gtacggaggt ggaccagcag ccgaagatgc gggacggcct
    14401 ggcggatctc ttcgacgtgg tctgcttcgc cgacgacgag ccgatgcgca agccggaccc
    14461 cgagatcttc cggctggtcg ccgaccgcgc gggcaccgga cttgacgggg cctggatgat
    14521 aggcgactcc ctggaacacg acatcgcggg cgccaccgcc gtgggtatgt cgacgatctg
    14581 ggtctccggc ggccggacgc cccaggacgg ggagtcggtc tccggacagg tcgtgacctc
    14641 ggtggccgag gccttccccc tgctgcacgc ggccgggtga gcttgggcgg cccgcggtgg
    14701 gaggaccgcg ggccgcgaag acacgtcgag cggccggggc atcccccggg ggcgttctcg
    14761 aagtcccgca cggcgtccgg cgcgcctctc gccgcaccgg ccgaaggccc aatccccccg
    14821 cgccacgtag tccttcgtcc ggcacgccga aagcaggcac cgaagaccgc ggacaccgtg
    14881 cgggacttcg atgacatccc ctaacggacg acgcggtcgt cggccgagag ccgacgggac
    14941 cgcgaacggc gcaggtcgcg ggtgatgttc atccgcttca gccagcggtc cgagccgtcg
    15001 aagcgcgcct tgaacggccg gcgtccgtgg atcgcgctgt tgttgtcgag gaagaggatg
    15061 tcaccggggg tgaggttgac gtcctggagc ttgcggttga tctcggcaca cagtcgctcc
    15121 agcgccccgg ccgcctcttc ggtcagtgga gtcatgcagt cgggatcgac gcacaggtag
    15181 ggatcggctt cgtcaccgaa caggacgctc acggtcggcg ggttgcggtg ttgctcctcg
    15241 atccggtcga agctctcctt cgccagggcg tgccggctct ttggcaggtg ggtggtgtac
    15301 gcgttgcgct ccgcggaatg cgagccgctc ggccgggtgg cgaagagcgg ctgccggagt
    15361 gtggcgcggt ccgcctcggt gatgtcgagg tcggagatct cggcgtacgt ggtcggcgcg
    15421 ccgtaaggat tacgcaggca catcagcgcg gtgtagtccg cccggtgggg gtggaacgcc
    15481 tcctcggtgt gccactcgag ggtctcctcg gagccggagg agatctgctc cttctcatgc
    15541 ccctggatgg gcacgatgtc gtgcatcatc agcccgttct ggagggtggc gtacccgaag
    15601 gggtcgccga ggagctgcgc gcagaggacg aagaccgatt cctcgcgcag ggcgggcgag
    15661 accaccccgg cgggctggtg ccagtcggcg ggggtggggc cgatctcctc cccgatccgg
    15721 atgccggaca gcaggaaccc cccggacggc tcggtgagcc ggaatccgac gagtgccttc
    15781 cggagctccc ggggcaactc gtgcgccagc accgcggctc ttctgtggaa cgccgcctcg
    15841 tgcacgctcg acaggtcacg ggtcaactcc cgcaccagct cgtcgatgtc cgcgttggcc
    15901 cgggcgtcca ggtggtactt ctccatgtcc acgacctccg tagcagcagt gtggtccttc
    15961 gcgccggcgg tgccggtcac ccttctcggt cgacgagggc gtaggcccgt acggggaagg
    16021 tgcccatgtc cgcgacgggg atcggcgcgg cgtggaagcg gaagtcctgg cccacgacct
    16081 gtcccaggcc ggtcatgtgc tcgaccaccg ggatgccggc agcgaggagt ccggtgtgcg
    16141 cgggccgcgc caggtcggcc atgtcgtcga tgttgaccga gtcgataccc accagggcgg
    16201 ggcgcctggc caccagccag gcgacggccg cctccgtgag gaaggggtgg gccgggtccc
    16261 cgtaggacgg agtggcccag tgccggtccc agcccgtgtg gacgaggacg gcacggtcgg
    16321 tcacctcgag gccgtcgaac acctcggggc cgacgccgct cggagagccg gcggggacgc
    16381 tgaccgccac gccctccagg tcggcgaacc gggacagcgg cacctgcgag aggtccgcgc
    16441 cgccctcgaa gcggtggaag gggacgtcgg cgtaggtccc ggtgttcgcg acgagggtga
    16501 tgcgccctat ctggaactcc gtaccggggg agtagcggtc ccgggaatcc acgcgtgaca
    16561 tgtggtcctc gatcaccggc ccgggcagcc ccgggtaggt ggtcatgcct tggcgcacca
    16621 cgtgcgaaag gtcgacgagg tccctcttgg cggtggtcat cgtggagctc cgaatcgtcg
    16681 cagtcggctg ggcagggtgg ccagtgacag ccaaggcgtg taggagtagt cggacatcga
    16741 cgcgtggaac gtctcgccga accgtgtgta gtagagaccg ttccgcgagt tcacgctgag
    16801 cacggtgacg gccccccggt gcagccgcag ccgcacggaa ccctccaggg ggcggtccag
    16861 gtcggccagg catctggcca ggctctcgcc gagatggctg aaccagccgc cctggaccac
    16921 ggtcgtcgtc cactcccggg cgatcgcccc gcgaaccgcg tgctcctggg ccgtgaagac
    16981 cgcgttggcc atgacctggt gggccttgat gatcacggtg gcggcgggtg cctcgcggac
    17041 ctcgtggttc ttcacaccga acggagtgtc ctcgagcccg gaggaccggc ccactccgtg
    17101 ctccccggcc agcagattga ggcgttccac gaggtcgccg aaggcgatcg gcgcctcgtc
    17161 gagggccacc ggcagccccc gtcggaacgt gaggagcagc tcggccggct cggcgggagc
    17221 gtcctcgacg tcccgggtcc accggaagac gctttcgtcc aggcggttct ccgggctctc
    17281 cagggagccg cactcgatga cccgcgccca gggattggcg tcgacgctgt ggatgccctc
    17341 gggaaaggag atgcccgcct ccgcgagtgc ggccagcttg gcctcacgcg gcaggtcgga
    17401 gccgaggaac ggcgcggcca cgccgatctc cggggcaagg gcggcgatcg aaccgctgag
    17461 ccggatggaa ctgttctgca tgtacgtcgc cgtgtggccg atcacctcgc atccgtgttc
    17521 ccgcgccacc cggacggcag tcctggccat gagcggccgg gtgagcgtcg aaccgaccgg
    17581 gaactggtcc tggtacacgg cgtccgcgtg gacggcggca ggagcgaaca cgtcgaagaa
    17641 ctggtccgtc acgtccacgt cgatgaagct cgcgccgaac tgccgggcgt gtgcggccgc
    17701 ggtggccgag gattcgcggt cgccgatgcg aaggtgcagc gccgtcaccc tgactcccag
    17761 ggactggagc cgctggagga ggtaggtccc gtcgacgccg ccggagtaca gcagcagcat
    17821 gtgccgcggc ggctggtcgg cgatctcctc caggccggtc aggaacccat gcacgccgga
    17881 ccctcgattc gtggagtggt ggaagggccg gggacgaaga ggccgatgtc ccgcaggggg
    17941 tggcacacac gggagccggc cggtcggtcc gctcgcgagg agcggatgtc tgtgacggcg
    18001 aagcaccggc gcagccagcg gtcggttccg tcgtaacgtg cggtgaactc cgaacggccg
    18061 tggatggcgg tgcggttgtc gacgacgacc aggtcccccg cttcgaggac accgccccgc
    18121 aaggtggcga ggaaggcgga cctgagttcc tccagggccg ctcccgcctc ctcgtcgagt
    18181 gcgtccatgg cgtggaagtc ggcgaggagg tccgggacct cggccgtgcc ggagagtacc
    18241 ggcagaggct cggtgagcag gtcgtcggcg ccgcccccga acgagctgct caccctgagg
    18301 cggaagcgag gttccctcag gacgccggcg gctcgctcgg acagcagcgg cagcgccccg
    18361 gcggccgcgc cgacgacggt ccgggcgaca cgttcgtggt cggggcgtat gcacagaagc
    18421 gtgatgaagt ccggtttgga cgggtggaac ccgtcctcgg tgtggagttc gagatagacc
    18481 gtcccggagt tctcctgacg cctctcgtcc ccctggaccg gggtgatgtc ctggacgagc
    18541 ctgccgagct tctcgtccgc gtaggcgatg acgtcaccca cggtcgacgc cacggcgagc
    18601 tgcccgaaag tggccacggg aaggtcgttc cagtgggaga ggaacccgtc ggccggagtg
    18661 gcggggggcg cgaggtcgac cggcatgttc cggatcagga gcgcgccggc gtcgttgccc
    18721 tgccggcgga accggccgag tgcctccagg atccgcctcg gcagccggag ccccgcgaac
    18781 tcggcctccg tcagcacctc ctcgtcgtcc agcggccggc ccttcagggc gcgggccgac
    18841 gcggcgaaca cctcgccggc ggcttcgcgt tcggcggggg tgaggctgat cgccacgtcg
    18901 tcgagcggtg cgatggtgct gccggtggga tcgccgccgg cgacggccgg tggctgtgtc
    18961 ggttcacgta cctgaatcac caggcgcctc cctgaggtcg agactgattc cgggtccggc
    19021 ctgccgaaac ccgcacgggc tcgaccgtgc gcgtcgtcgc agacgaccgt tccggcctgg
    19081 cggattcatt tattccgctt gccgggcatg gcctgggaat gcgccgggac gagccggaac
    19141 cgtgtggttt cggtggttga gaccgctact tttccagagg ttccagccgg gtcccgagtg
    19201 gcggaccggg gtcgcgcctc gatccgcttc gtgaaggttc ggcctgtccg gcattctgtt
    19261 gcggtgccgg agttccgaag gggcacgacg ctgtggtatt gaatggcgta cccgggctgt
    19321 gcccgtctgt gtcgcccatc gaagacaccc ccgtgtcaag gccttcacct tttgcgtccg
    19381 tcatcgaaac agaaacgtcc gaacggcgca agcatcttcg tcaagtcgcg tgcagagatt
    19441 gactcttgcc tcctctgcgg gcccaaacta tagtgcagct cgcggctcgc gaggcgtgcc
    19501 gaaaattgcg tgaaacgggg gatgcggagt gaggatggaa cggggtggag cgacggagtg
    19561 tcagccgtcg cgcaggattt tcaggacttt ctctttccag tggggcgaac ttccggacat
    19621 tttcgggcgc gtccagtagg gctccaagcc tcttcggtga ctcccctttc cgtcggtcac
    19681 cccgcagcta ttgcgtgatc cgcctcgttc gaggctgatg gccgattcgg ggagcgtccc
    19741 gcttcttcgt gatgggtgtg tgcgacttcc cgcgccctgc gattcttcag ccagaactgc
    19801 cgccggggta tccgtatgcc cgcatccggt gagttccgcg agtttgccgg atgagctccg
    19861 tgctcccgat ccggcaggtt tcgctgggat gggtgaaatt tgccttcctt cgttgttcct
    19921 tccattgtgc cccgaggtca tgggcttcgc ggcgaagaaa ttgcactgcg cagggggaaa
    19981 cgcaccgtgg atttctgtaa atgagccggt ccaccattca cggcctcata gccgcacgtg
    20041 ctcggtcgac cccgggcctt ccggccgtcg agtacgggga cgaatgcctc gacttccgcg
    20101 aactggagcg ccggtccgac gccgcggccc ggagactgag cgcgcacggc gtcgcgccgg
    20161 gcgtcttcgt cgcggtgtcc ctggagcgtt ccgccgccat ggtggtgacg ctgctgggca
    20221 tcctgaaggc gggtggcagc tacgtcgccc tggatcccgc gtatccggag gcacggctgc
    20281 gctggatcct cgaggacatc gccccgcgcc tggcggtggc gagccgcgcc atgcggggca
    20341 cggtgccccc ggccggtata ccgctcctcg tcgccgagga gctggacgac gcgtcgccgg
    20401 cgcacggaac ggacgtcgcc ccgatgccgg gggagccggg cgcggtgccc tccgaaggcg
    20461 atcccgagag gctcgccttc atcacctaca cgtccggaac aacgggccgc cccaagggcg
    20521 tcatgcacgt gcacgactcc atgacctact tcatggagat gatcgagccc tacctgggcc
    20581 tcgcgcccgg cacccggttc ctccagttct acccgctgac ctgggagatc caggccctcg
    20641 acatctacgc ggtgctcgcc gccggcggca ccgtggtcat cccgcccgcc ggcaccgaga
    20701 cggccgggcc cggcctggtg cggttcctcc gggacgcccg cgtcaccacg gcgctgctgc
    20761 cccccgcgct gctcgccgag ctggccgagg aaccgcccct gccggccctg cacacgctcg
    20821 cctacatcgg ggagcgatgc cggccccgga cagccgaacg ctgggggagc ggccgacgcc
    20881 tgatcaacct ctacggcccc accgaggtga ccgtcgcggc cagcgcctcg gacgaacgcc
    20941 cgcccggcga cgcaccgccg atcggcaagg ccctgcccgg tcgcgaactg cacgtgctcg
    21001 acgagcagat gaatcctgtc gccgaaggcg cgccgggtga actccacgtg ggcggccggg
    21061 gcctggcgcg cggatactgg agactccccg aactcacgga acgccagttc ccgcaggacc
    21121 ccttcagcgg gcggcccggc tcccgcctct accgcaccgg cgaccgggtg cggtacctgc
    21181 cggacggcaa tctggagttc ctgggccgcg tggacggaca gctcaacgtc cgtggccagc
    21241 gcgtcgaacg gggagagatc gaagcggtga tggccgcaca cccgggcgtg cggtcctgcg
    21301 cggtcgtcgt ccagggggag ggctcggacg ccaggctcgt gggctttgtc gtcggcaccc
    21361 ctggggtgga gaaggaactg ggcgaccggc tggccgatga gctgccgccc gccatggtgc
    21421 cgtcgttcct cgtgcccctg gagcgcctcc cgctcaatca gcacggcaag gtggatctgg
    21481 ccgcgctgcg cgcgcaccgc cggcgggggg cgggctcccg cgtcgcccgg ccggctccgc
    21541 gccccgggcc ggaggctgac ctggcccgca tctgggagga ggtcctggag gtcgaggagg
    21601 tcggtcccga ggacggcttc cgcgccctcg gcggtacctc gctccaggcc atcagggcgc
    21661 agaaccggat ccgcgaacac ttcggcgttc cgctgaccgt ccgggaactc gtgggcgccg
    21721 gcaccctggc ggacctggcc cgccttctgg cagccggcga cgccggacgt ggtgccctgc
    21781 cgccgctcac ccgcaccgcg gccggcccgt cgcaccccgc ctccctgcac cagcggcgcc
    21841 tctgggccca ggcccgggcg aagcaggccg cgtccgtcgc ctacaacgag acgtccgccc
    21901 tccacatcac cggacccgtg gacctgtccg ccctgcggcg cgcggtgcag gacctggcgg
    21961 accggcacga ggcctttcgg agcagtctgc acctggacgg cgccgacctc cgcgtcgaca
    22021 tcgccgcgca cgtcacggtg gagctggccg aggaggatct gaccgggacc gccgatccct
    22081 tcgcggcggc cactcggcgg gtcgcggaac tcggtgccct ccccttcgac ctggagcggg
    22141 caccgctgct cagagccacc ctgctcgacc tgggggcgga gacacgggta cttgtcctcg
    22201 tcacccacca caccgtcgct gacggcctct cgcaggacgt gctcgaccac gacctggcgc
    22261 agtgctacgc cgcgcgcggg gcgggacggg aaccggctcc gcggcccggg aaggagctcc
    22321 gcccccgcga ccacgccctg tggcagcgca ccacggccgg gcacccggtg ctcgcggcgg
    22381 gtctcgatca ctggcgcgcc gtgctcgacg gcgcccccac cgtgacgaac ctttcgaccg
    22441 cgggtacccg gtcggcctcg ttcagccacc tcggtggccg ggtgaaccac gagacgggac
    22501 ccgaactacg cgcggcggtc gaaaggctgg ccaaggaggc gggcaccacc ccgtacgcgg
    22561 tgtgtctcct ggccctcgcc gtactggtgt cccggcgcac cgggcagcgg gacgtcctca
    22621 tcggctctcc cttctcgggc cggccgagcc aggaggccga ggacgtcatc gggttcttca
    22681 ccaacaccgt ggtgatgcgg gtgagactcg acggccgcct cgacccgctc ccgctgctcg
    22741 gcgccgtgga cgagcggatc caggagggcc tggagcacca gtacgtcgcg ttcaacgacg
    22801 tcgtgcgggc ggtaggcgcc cggggcggca cgtcgggcca gccgctcgtc caggtggtcc
    22861 tggcctacca ggggccgttg cgtccccgcg ccgccctcac cggggcccac gtggtgccgt
    22921 ggctcgtgga caacggcacg gccaaggccg acctgacggt ggagatcaac gaggtcgggg
    22981 acgaactggt cgtggtcctg ccgtacagcg ccgacgtcat ggacgagccg gtcgccgcgc
    23041 gcacgctggc ggagtacgtg gagatcctgc gcgaactgac agtcccccgg ccggacaccg
    23101 cacagtcctg acgcgcgggg ggcccgcccg gtgccggacg ggttcccgcc gaccgacaag
    23161 ccaacctgaa gggaagcccg gtggatcttt ccacgttcct cgcccaccac ctcggcgcgc
    23221 gcggtgccga gccggccctg gagtcgggta cgcggacctg gtcgtacgcc gacctggacc
    23281 ggatcacccg ggaccgggcc gcgcggctgc gcggcctcca cccgaaggcc gtacgcatcg
    23341 cgctggtcgg cgagcacaca gcggaggcgc tcgtctggac gctggccgtg atgcgcgccg
    23401 ggctggtcca caccccgctc agccccggcc ttccgccgga gcggatgcgt gaggccctgc
    23461 gtgtggccgg acccgacctg gtgctccgct gcaccaccga gcccctgcgc gaggaggacc
    23521 tcggcaggcc ggtgatcgac gcggctcaac tggccgccgg ggcttctttg gcggacggtg
    23581 ccgagagccc ggtgtcctgg cccgtgcagg agacggccta ctcgatcttc acctcgggat
    23641 ccagcgggct gcccaaactg gtgaacgtcg gccaccaggg cgtcgaggcc ctctgcgagg
    23701 cccagacgcg cttgttcggt gtcgaacctg gcgaccgtgt gctccagttc tcctccctcg
    23761 ccttcgacgc ctccgtcgcc gaggtgctcg tgaccctcta cgccggcggc accctcgtcg
    23821 tccccgtatg ggacggcggc tcctgggtga acgcggtggg cacccacctg gccgagcacg
    23881 gctgcgacgt gatcaccgcc ccgccgtcgg tgtacgcgcg gctgaccgac gaggcgcgca
    23941 agatgatcgg cacggtcgtc ttcgcgggcg aggccatgac cgaggtcgac ttccggatgg
    24001 cggcccggtt cagccgggtg ttcaacgcct acggccccac cgagggcaca gtctgcttct
    24061 ccgtggccga gccgagccgg ttcaccacct cggtcggccg ccccgtcgac gggtacgagg
    24121 cccgcgtcca cgatccggcg acgcacacgt acaccacgtc gggactgggc gaactcgtca
    24181 tcgtcggcca gggagtcgcc ttggggtacg aaggtgtgga gcggggagaa gcacccttca
    24241 ccacggtcga cggggccagg gcctatcaca ccggggacga ggtcgaactc cgcgacgggg
    24301 aggtcttcta ccgtggccgc atcgacgacc ggatcaagcg tctcggccac cggatcgccc
    24361 tcaccgagct cgaaggccgg ctgtccgcgc tgctcggatc gcgcgtcgcg gtactgacac
    24421 acgaaggctc tctggtcctc gcccacacca ccaccggccg gaccgagcca gagctcaagg
    24481 cgtggctgcg cgaggtgctc ccgaactggg aagtgcccga cacactcctg ctggtccccg
    24541 acatcccggt cgggcacacg ggcaaggccg acaaggacgc cctgcgcgcc ctcgtcgggc
    24601 gcgacggcac cggcacgcgg tccggcggag ccggcgagga agccggtcag gacgccgtga
    24661 gtgccctggt cgaagaactc ctcggtgtcc cggtcacccc cggcacgtcg ttcttcgacg
    24721 cgggcggcga ctccttcggg ctcgtgcaac tccaggtcaa gctcgcccag ctgtacggcg
    24781 aggagcgggt gcagagcgcc ttcgacctgc tcaactacga cttcaccgtc gaggggttcc
    24841 tcgccgccgt gggcgacgct ccgcaggccg cggcctcccc ggtacccgcc gtcctccgca
    24901 cggtctccag cgatctggcc ggactgaccg cctcgctcac ggccctgcgg caggaggcat
    24961 caggtgcccc ggggacggtc accgtcaccg gagccggtgg attcatcggt gggcacgtcc
    25021 tcgacaagct gctcggcacc ggccgtccgc tggtcgtcgt caccaccagc agcccccgcc
    25081 gcgtcgtcga gcgccactgt gtgcggttcg gccgtcagga ggccgacttc tccgatgtgc
    25141 ggttcctgag ctacgacgac ctggaggcgc cggcggagga caccggaggc tggggcgccg
    25201 tcgtgcactg cggctaccac gtcaaccacg tgctgccact ggagcgccag gtcaaggaca
    25261 gtatcgcgac gacccggacc ctggtccggg cagcggccga gcgcggcgcg catcagttcg
    25321 tgttcgtctc cgcggcctcc gtcggccagg agttcgtgcc gctgaccgag gacgccctgg
    25381 aggccgtcgg cgacccgtac tcccagtcga agttcgtggc cgagagctac gtcggagcgc
    25441 tcgacggcac gggctgccgg gtcgacatcg tccgcaccgg actcgtgtac gggcaccagg
    25501 cgggcgacgc ggccttcctc gacgacgatg tcttcgccaa cctgctgcgg atctccgggc
    25561 agcgccgcgt catgccgagg ctggccggtc tcgtgccggt gtgccacgtc gccgacgtcg
    25621 tggagacgtt gctgaccgcg gccgccgggc gggcggcgga gcggcgagcc gtcctcttgc
    25681 agcgcaccta cgacaccgac cagctgagcg ccgagctcgg cggcgtggcc ctggccgatc
    25741 cgcgggagtg gctcgcggcc gtgacagagg ccggtgccac ggacccccgc gtgctggccg
    25801 cactccggct ctggctcgac gagcagggct ggagcggacc ggtacacgcc acgtgccggc
    25861 cgatcatccg ggaactcatc aagaccttgg agatctgacg catgacttcc gacacggcca
    25921 tgaccgtggt ttccgagcag cgctgggatc cgggcccgcc cctcgacgcg gggttcgtcg
    25981 acggcgagat cagcatccgg gaggagcttc gccggggcga cttcacccgc tggcgacgcg
    26041 ccggcggcca cgagctgcgt gagcggctca cggaccgtcc cgagcggctg ttcctcttcc
    26101 agacggaggg ccactggtac gcgggctgca agacgatctc cgactacgtg ctcgaccagg
    26161 gtatgccggg tgtcttctgc agccgcgtgt actggtacaa cgtggtcggc acggtgacgt
    26221 ccgtccgtac ctccgacact gacgcccgga tcgtcttcga gccgctggac gagaccggcc
    26281 gccgtgccgc cttcgaggcg atcacgccac tcacggagat cgtgcacccc ttcgccaagc
    26341 agcgtgatcc cggccgcgag aagaccagcc cctccgacgg ctggctggtc acggaggaac
    26401 gcgcggcgtt cctcggtctc ggtgagcagc acctccggcg ctacacccgg gaacggttcc
    26461 gatcgtggtg cgaagccgcc gacggcgacc tcctcgcgta cgacccggcc tgctcgacgg
    26521 gtcagttcct gtccgagttc gccaccatgg accccgcccg gatccgcacg gtgggccagg
    26581 acctgagcag ccagatggcc gacttcgccg cctcccgtct ggagagggtc gtctgcggtg
    26641 acgcggcctc ccccgccgtc gagtccggca gcgtcgacat cctgttcagc cggttcctca
    26701 actccgaggt cgtctccacc gcccaggccc ggtcccttct gccggcactg gtcgacacgc
    26761 tgcgtccggg cggaaccatg gtcctgctcg gacacagccc cgtcctgctc gacgccgtgg
    26821 acctggtgag cgccgggctg cgcgtccggc agaccgtcgc gcgccaggac gaccacctct
    26881 tccagtacta cgtgtgtgaa cacggagcct gatgtgaccc tgtctctcaa gaagaacgtc
    26941 atcgcggagc cggccgtcgc gggatggtac gcctggtcgt acctgctccc tcctcagacg
    27001 ctggcgaagt acctcaagaa ccactaccga aacatcgtcg agtcctacct cgccgacccg
    27061 cagacccacc gcacggcact gcggaacgcc cgcttcctcg gcggcccgtt cgtgtacgag
    27121 caggacggct cctacgaccg gatccgcaag tggtacgaca ccgcccgcga gcagtacgcc
    27181 ccgctcctcg aactcgccga cgccatcgac gagctggagc agaagatcct tccggagcag
    27241 accggcgcgt cactggacca ggtgtaccgg caactgcccg cgccgctggc cggccgtgtg
    27301 gagttgttct acaaccggga caaccgcacg ccggactacc ggttcatcga gccgttcctc
    27361 tacgcctccc cctacttcga caccgctctc cagcaggtca ggttctccga ggtccaccag
    27421 gacgcgcgcc agttcgccct gaccaccccg gtcctcgcct acacccccga gcaggtgctg
    27481 gtcacggtgc cgctggaatc ggaactcctc gacacggtct tccgcggcgg actcaccgag
    27541 gaggagctgc gccgggtgat cgacggcctt ggcctcgacg gggaacgcgc tgccgccttc
    27601 aagggcttct tcgcagagga cccggagccc gcggacagcc cggggcacgc ggagcccggc
    27661 gaggacgtcc tcgaatacgt gggccacgcc tgcgtgttcg tccggcaccg ggggaccacc
    27721 ttcctggtgg acccggtgat cagctacagc ggctacgggc acgagagcga cggcaggttc
    27781 accttcgacg acctgcccga gcgcatcgac tacgtgatga tcacgcacaa ccaccaggac
    27841 cacatgctcc tggagacgct catcaagatc cgtcaccgtg tggggcgcgt cgtcatcgcc
    27901 aagtccgcca actccagcct cgtcgatccc gatctcaaac ggatcctgac gggtctcggc
    27961 ttccgggaca tcgtcgaact cgatgacctg gacacgctcg acacccccgg cggcagcatc
    28021 accgcggtgc cgttcctcgg ggagcacggg gacatccgga tccgtaccaa gtgcggctgg
    28081 atgctggacc tggacgggac ccgggtgctg ttcgccgccg actccaccaa cgtctcgccg
    28141 gagctgtacc cgcaggtgac ggccgcgctc ggccaggtgc acacggtgtt catcgggatg
    28201 gagagcgtgg gggcggcggt cagctggctc tacggcccgc tcttcccgga gaaactggaa
    28261 cgccggatcg acgcgggccg gcggttgaag ggcagcaact tcgcacaggc ggcggagatc
    28321 gtcgacgcgc tcggcgccga ctccgtctac gtgtacgcga tgggccagga gccgtggctc
    28381 ggcgcggtca tgtgcgtcga gtacgacgag aagcatccgg cgatgatcga cagcgacaga
    28441 ctggtcgccc atgtcgggga gcggggcggc accgcgaagc ggctgttcct gcacgagacg
    28501 atcgcgattc gcccgtgaac gcgggcaagc cgcacgtcgt ccacataggg ttccacgcct
    28561 ccgaggcgca caccgtggac ttcgaggccg accacgtgac cgtcgtgatg cccagggcga
    28621 gcgccgcgcg gctgcccgcc gccctggccg cgaggttcgc ccgcatcgag gtcctcgacc
    28681 tgcccgattc ggacgacctg gacacgtacg accgcgccgt ggaccggatg cgcgagctcg
    28741 tggaggacct ggtcgcgcag ttcggtccgc ctgcggcgat cgtcggcctc tacgagcaca
    28801 ccacgctgcc ggcggcccgg ctgcgcgagc acttcggggt gccgggcacc ggcgcgaaga
    28861 cggcgctcct gtgccgggac aaggtgccga tgaaggaggc cttgtcgggc accggcatcc
    28921 gggtgccgag gttcctcgcc gtgggcccgg acaccccgcg cgccgaactg agcgagttcg
    28981 cccgcggact gcccggccgg gtggtgctca agccgcggag ccagggcgcc agcatcggcg
    29041 tgcgcattct ggacggcgcc gcggaactcc tggccctggc cgacgccggc ggcatcgagg
    29101 aggggtacga ggccgaggag ttcgtcgacg gctccatcta ccacatcgac ggtgtggtcc
    29161 gggacggcga gatgcgctgg ttctgcgcct cccgctatct cgacacctgc ttcgacttcc
    29221 ggcacggcac cgctcccctg ggggcggtga cccccgacag ccccggactc gtgcgcagga
    29281 tgcgagacgt caccgggacg gtgctggaag ccctcggact cacggacagc acgtaccaca
    29341 tggagctgtt ccacaccccc ggcgacgagc tggtcttcct ggagatcggc aaccgcttcg
    29401 gcggggccgg catcagttgg caccagcgcc aggtctacgg cgtcgacctg gcccgcgagt
    29461 cggttctggc ctgcctgggc cggccgtccg aagtggccac gcccacgacc atgctggacc
    29521 accgggacgt gggcgcctcg ggatggttgt acatgccggc cgtcagcggt gccgtccggg
    29581 tcgtcgccgt ccgcgggctc gacgaactcc ccggctccgt ggtgggcgtc aacaccccgt
    29641 cggtgggtga cgtcctcgac tccgaggggc tcatctgggc gaccgctgga gggttcctcg
    29701 tccgcgggga ttccacgctc gcggtggagc gggacatggc gcggatcatc agcacgtaca
    29761 cactcgagac gaaggcaggc gactagtggc tcgtacgagg ctcggcacgc acatcggagt
    29821 cgtcgtggac gactaccggc tcgacccggc ggacccgggg ctccgcgact tcgtcaccga
    29881 gctgctgttg cagcacaagg tggtgttctt caagagccag cacctggacc ggcacacctt
    29941 catgcaggtc gcgaagcgga tcggccggac cgaggtgcac cccttcatct ccgaggacga
    30001 gcccgtggtg cacggcatct caccgttcca gccgtaccac gagtatccgg agatcaccgg
    30061 catctaccac gacgaggagc acacggggaa cctcaacgcc tggcacagcg acctcaactg
    30121 gcgcgaggtg ccgaccttcg gctcgctcct gcgcgccgtg cagatcccgc cgcgcggtgg
    30181 cgacacctgc tgggcgaaca tggcggcggc gtacgcctca ctcagctccg aggtcaagga
    30241 gcagcttgac ggtctgcgcg tcgtccacga ctggatgcag atctacttcc ccgccttcga
    30301 cggaaacgac gaaacactgg cccgtatgcg ggagaagtac ccggcgcaat cccaccccct
    30361 ggtcctcacg catcccttca ccggcgagaa gtccctcttc tccaacaagg tttcgggcgt
    30421 ccgcgtcgaa ggagtcgacg aggcggagag caagcggatt ctggatatgg tgcacctttt
    30481 ggcgtggcgc ccggaattcc agtgccgctt ctcgtgggaa gagggcgacg tggcgatctg
    30541 ggacaacctt gccagccagc attacgccgt ctccgactac tggccgcaca cccgcaaaat
    30601 ggaacgcatc accctcgaag gcgagtcgat caagtgagca ctcaagtcat tgtcctgaac
    30661 ggtggatcca gctccggcaa gacggggatc acccgctgcc tgaaggcgat cctcccccat
    30721 ccgtggatca acctcggcgt cgacgacctg atcgaccggc tgccgccgtc cctggtcgag
    30781 gccggctccg gcgtcgagtt cggacagcag ggcgaggtcc acctcggcga cggcttccga
    30841 gagatggagg aggcgtggac gaagggcgtc gcggccatgg cgcgtgccgg agcccggatc
    30901 atcatcgacg acgtgtttct cagcggagcg gcctcccagg accgcctgcg ggcccagctg
    30961 gagggtcttg aggtgctctg ggtcggcgtg cgctgcgacg ccgagatcgc ggccggccga
    31021 gaactggccc gcggtgaccg ggtcatcggc atggccgtct cccaggcgga gatcgtgcac
    31081 aagggcgtca cctacgacgt cgaggtcgac accagccgca ccgagtccct ggactgcgcc
    31141 cggacgatcg ccgctcgcgt gagctgaccc cctggtgagc acgcccgtgg gcgcgggcgt
    31201 gctcaccgca gtgatggacg gagcgaggag acagagcatg gacagtgcgg aaactgacgg
    31261 gtcaggcgcg gactcggccg tgtcgcaccc gccggggcgg ccggccgcgc agaagacgtg
    31321 gggcaagttc tggctactga cttccgcggc gtcggtctcc gagatgggca acaccttcct
    31381 gcacctggcg atgccgtgga ccatcctggc cagtacggga tccgccctga tggccgcgct
    31441 cagcctgggc gtgcagtacc tgccgttcgt cgcctcgccc ctgctgggca ccctgatcga
    31501 cggctacgaa cgccgcatgg tcttcatggt ctcggaactg gtccaaggcg tgctcatcgc
    31561 gctgaccccg ctgctgctca tggcggacca ggtcgagctc gtcctcgtgg tgctgttggt
    31621 cgccggctgc ggcaccgtga cctccaacct gaccagcgac ttcagtctgc tccccatgct
    31681 cgcgccggag aacaggctca ccgaggcgta cagcaggttc ggtgccgtga cggaactggc
    31741 ccgcacggcc gggccggccg tcgccggact ggtgctcgcc gtggtcggag ggtacggggc
    31801 gctgtggatc gacgccgcga cgttcctggt cacggcggtc atcgcggcct tcctgccgcg
    31861 cggtgagaag ccggtcgtcg aacgcggctt cctccgcatg caggtcgagg gcttccgcag
    31921 cttccggaag atccgcggag tgccgcggct caccctggtg ctctcggtgt acaacctcgg
    31981 cgcgggcgcc gtaccgacca tcatcctggt cgtcgccgcc ggaacctggg gctggtccag
    32041 cggcctggcg ggcgcggtcc tcgcagccgg ggccgccggc agcgccctcg gttcgtggct
    32101 gggcggcagg ctctggcaca acgcctcggc ggaacgccgc atccggctct ggttcctggt
    32161 gtgcgcggtc tcctccgtcg gcctcctggc cccctgggaa gaagtggtgg tcctcggctt
    32221 ctgctgtctg atggccgggg aaggaggcat gaacgtcacc acgaacgagt accgcttccg
    32281 ggcgataccc gatgaggtgt ccggccgggt caacgccgtc atgcgggcgt tcatcctggg
    32341 cggcgccgcc ctgtcctccc tgctgctggg ctggtccgtg acgctgccgg agcaggtact
    32401 gcggttcgcc ccggccctga tcacctcggt cctggcggtc ctgatctggg cgggcgtgcg
    32461 cagcttccgg gcgcctgtgg gaaccgaacc ggagaaggcg gcctaggacc tgcccgtctt
    32521 cgatcacgac gtacgctgcg agaggaacga catgctctac atgttcgcct tcgacaaggt
    32581 cggcatagtg gtgggggatc tgtacttcgt cgatcccgaa ccactcaagg gacaggagag
    32641 cgccgagcac ggggtccggc tcgagctgag actggtcgag cagggcgcac tcgtggactc
    32701 cgtctacgcc gcctacccga tcaccgtgga ccagccggtg tggcgcgccg acttcctgga
    32761 gtcggtcgac ggcaggcccg ggagcttcga ccggacccac caccacccgg tcttcacggg
    32821 ctgggacccg ggcgaccggg tcttcgtccg cgagctgtcc gccgacccga tgggctggct
    32881 gggcgaccgc ctcgccgacc tcggcggttt gctgaagacg gccggtctcc ccgccgacac
    32941 ggccggtccg gccgacgccg ccgagctgcg cagggcggct ccggagatcg tggacgcgac
    33001 ccgcaggctc ctcgaccggg tccgcgcggg cgagatcggg aaccggccgg cgggtgtacc
    33061 gcccgaaccc gtcgaggggc agttccaggc gctggtccgt tccggctggc tgtgagtcct
    33121 cgggggcgcc ggccgcccgt tcggggggcc ggcgcccccg aggggcggtc agtagcccgc
    33181 ttctccgacc acgttggcca gcggctcgcc ggcggcgtag cgcgccagtt gggccttggc
    33241 cagagccatg gccctcgccg gcggcgaggt gttcgacccg gcggtgtgcg gggtcaggat
    33301 gagtccgggg gccgaccaca aggggtgccc cgccggcagc ggctccgggg cggtcacgtc
    33361 gagtgccgcg tacagccggc ccccgcgcaa ctcggcgacc agcgcgtcgg tgtcgacgag
    33421 gcggccacgg ccggcgttca ccagcaagcc gccgtcccgg atgcggctca ggaacgtggc
    33481 gtcgacgagg ccggtggtgg cctcggtcaa cggcagcagc aggaccacga tgtccgcctc
    33541 gggcagcagt ccgggcagct cgtccacgcc gtgcacgccc gggcgggccc gccgggccac
    33601 ggctgcgacc tcggcgccga agccggccag caccggggcc agggccgagc cgagggagcc
    33661 gtacccgacg agcagcacac gcttgccctc cagggagtcg gtgtgtgtgt agtcccagcg
    33721 ctcatcgcgg cgggcctgct cgaagcgcgg cagtcgcagc agatgggcca ggacgacgcc
    33781 ggtgacccac tccgtgaccg cccggtcgta cgcgcccttg gcgttgcaca gcacgacgcc
    33841 ttccggaacg tacggcctga tccactccac gccggcggac tccagctgca gcagccggag
    33901 ccggggcagc tcggcgaacc gggacagaag gtcggcaccg acgccgtagg gcgggatgat
    33961 cacctccacg gtgtccgccg acgccggaaa ttcggcctct ccggtccaca catcggcccg
    34021 gaaccccgtc ggcagcccgc ccatgagcgc ctcggattcc ggagtcggta gccagacgga
    34081 gatcttttcc gtaaagggga atgaggcgct ccggaaattc tccggattgt tctgtgtgcg
    34141 gggattcatg tgaggtattt tagcgtcccg gtcgtgcgcg cggccatgtc gtggaatggt
    34201 gtgcaatccc cgattgtccg cgcagaaccg gcagtttcgg gcggcggacg agtggtgtcg
    34261 gtccggaatt ccagacggtc cggaaacctg ttgacaggcg ttcggggatc cagcaagaat
    34321 caagacgggt gaaaatccct tccggttgcg gtattcacct ctcggatcct tgggcccagc
    34381 ggattgatcc gcgaatgggg cggcttttcc tcggagtcgt ccgggccttt cgtcagccgc
    34441 cgcgtcccgc gttcgccgca cggcgtgcgc cggtctgcgc gcacggctcg tctccgtaca
    34501 gaccgaagga atctcatgac cgacctggcc gttcacagcc cgtacaccga cgcgcgggag
    34561 gcgcccgtcc tgctgctcgt gggcagcggg taccgcccct atcgcgagta catcctggcc
    34621 gcggtctccc agcactaccg gttgtggctc ctggactcgc acgaggcgac gtggcagctg
    34681 cggtactgcg cgggcgccac tcgcgtcgac acccgcgacg cggacgccgt gcgcgaggcg
    34741 gccctggccg tcggtgagtc cctgcgggtc gtcggcgtct tcacctacga cgagacgcag
    34801 gtcgtgtcct gcgcgcgcct cgcgcaggac ctcggtctgc cgggcagccc gcccgaggcc
    34861 atcaccaact gccgtgacaa ggcggccacg cgtgccaccc tcgccgcggc cggggtgccc
    34921 cagccggcct ccgtcgtcgt caccaccgcc gaggaggcac tcggcgcggc ggagaggatc
    34981 ggctacccgg tcatcgtcaa ggcgcgtggc atggccgcca gtttcggcgt cgtccgcgcg
    35041 gacgacgccg ccgacatcgc ggccgccttc gccgccgccg acggcgccga cttcatggac
    35101 ctgccgcgct accccgcgaa cgtgctggtc gaggagtatc tgaccgggcc ggagatcagc
    35161 gtcgacgccg tcatccacga cggggaggtc actccgaccg tcatcgccca caagcggctc
    35221 ggcctcgaac cgtacttcga ggagacgggc cacgacgtcg acgcgcgcga cccgctcttc
    35281 gaggacgagg aactgctccg ccagctccgc gacatccacc gcgccctcgg cctcacccat
    35341 ggtgcgaccc actccgagtt caagctgacc cctcgcggcc cgcgcctggt ggaggtcaac
    35401 gcacggctcg gaggggacct catcccctac ctcggcctgc tcgccacagg cgtcgacccc
    35461 acggtcgcgg cggcgcacgc cgcagccggc cgcagggccg acctcactcc ggtccaccgc
    35521 aaggcggcgg ccgtcaggtt cctgctgccc gagggccgct gccgcaccgt ggaggtcgtc
    35581 acccacacgg accgcttcgg gcccacggtc cacgagaccg gcatcaccgc tgaccccggg
    35641 gacgaactcg acctgccgcc ggccgcgttc ttcacccgct acggccatgt cgtggccgtg
    35701 ggggaggaca tgggccaggt ccaggaggac ctccgggagc cctggcgtct gttggaactg
    35761 cgggccgaag cgctgcccga ctgaacccgt cgcccgagtc caccggcccg gctcccagca
    35821 ccgtgaccga gccgtccgat ccgcctccgc gccggcgggc cgggcggcga gaacaggacc
    35881 ccgcatgacc agtgtttccg agcatctcga caccgcgccg gtaccacgtg cgccggtgcc
    35941 cggcggtgtc cggctggacg ccgccgaact gcacgcctcg gtgagcgacc cgtgcctgac
    36001 ggcgatgacc ctgctcaacg acatcgccgg acgccacccg gacgccgtct cgttcgccgc
    36061 gggccgcccg tacgagggct tctacgaggt cgccgcgctc ggggaccacc tgaccgcctt
    36121 cgagcggcac ctggtggacg atctcggact ggggccggag gacgtacgcc ggaccttctt
    36181 ccagtacggc cgcaccaagg ggttcatcca ccacctgatc gcccggcatc tcgccagtga
    36241 cgagcggatg acggtcgacc ccgaatcggt gctcgtgacc accgggtgcc aggaggccat
    36301 ggtcctggtc ctgcgggcgc tgtgccgcga cgagcgcgac gtcgtcctcg ccgcgtatcc
    36361 cacgtatgtc ggattcctcg gcgcgacccg gctcgtcgat gcgcaggtgc ggccggtcgc
    36421 cgaagggccg ggcggcatcg acctcgccga cctggcggag cagatccgcc gtgcgcgggc
    36481 cgacggcctg cggccgcgcg cctgctacgt ggtgcccgac ttcgccaacc ccggcggtgt
    36541 cagcatcccg gaggccgacc gccgcagact cctcgagctc gcggagcggg aggacgtgct
    36601 gctcctggag gacaacccgt actcgatgtt ccacgggggc gagggccggc tgcccaccct
    36661 gaaatccatg gacgtggggc accgggtggt ctacttcggg tcgttcgcca agacggcgtt
    36721 cgcgggcgcc cgcgtcgggt acgtggtcgc cgaccagccg atggccgacg gcgcactctt
    36781 cgccgacgag ctcgcgaagc tcaagagcat gctcacgctc aacacctcca cggtcgccca
    36841 ggccgtcgtg ggcggctttc tgctgaggaa cgactgcagc gtggaacgcg ccaccgtacg
    36901 ggaggcccag gtctaccgcg acaacctgcg tgccgtcctc gccggcctgg agaagcactt
    36961 cggtgaggac ggcgcgctgc ccggttccgg ggtctcgtgg aacgttccgg agggtggcat
    37021 gttcgtcgtc gtcaccctgc cgatgcgcgc ggacgacgtc ctgctcacgc gctccgccga
    37081 gcgtttcggg gtgctctgga cacccatgta ccacttctac gcgggggagg gcggatcaca
    37141 ccagatccga ctgtccttca gcgccctgac tcccgagcgg atcgacgtgg gcatcgcgcg
    37201 gctcgcccga cttgtcgccg accgcgcctg acaggaggcg cgtacccacg ggaacgccgc
    37261 tcgccgctca ccgatcaccg cacacggggg aagacacacc atggaacgga cagcacgcgg
    37321 atgcgtcgtg cccgacgccg ggacaacgaa ccccggaggt gcggcgtgac ggccaccgcg
    37381 acgggccctg acacccggcc ggagcccggg caggacgcca acctgaagcg cgatctcggc
    37441 tactggagcc tgacaggcgt ggcgtgcggc ggcatcatcg gttcgggctg gctcttcggc
    37501 tcgttctacg gcgcccaggc ggccggcccc gcggccgtga tctcctgggt gatcggtggt
    37561 gccgcgctga cgctggtcgc cctggtcctc atcgaactgg gcgccggcag gcccgaggcc
    37621 ggcggcatgg tgcggtggcc gttcatcgcg aacggacccc tcgcgggcac tctcatcggc
    37681 tggaccatgc tcctcgcggt cgccagcacc atggccgccc aggcctccgc catcgtgcag
    37741 tacgccaacc gctacctgcc gggtctgtac gaggacgagg cgctgacgct ccggggccgg
    37801 ttcgccggcg tggggctcct gctggtcctc gtcatcctga actggttcgg ggtcaggctc
    37861 ttcgcccggc tgaacctgct ggtcaccgcc gtcaaggtac tcgtccccgt gctcacgatc
    37921 gtggcgctgc tggtgtcgag cttccacccc ggcaacatct cagccggcgg cggcttcgcc
    37981 ccctacggct ggtcggcgtc actgaccgcg atcgccggtg cggggatcat ctacgccatc
    38041 gacggcttcg cctcaccgat cgagctgtcc gccgaggcga agaacccccg gcgggacata
    38101 ccgcgcgcgg ttctcaccgc catcggactc gcggtcctcc tgaacatcgt gctccagctg
    38161 acgttcgtct tcgccgttcc gacggagagt ctcggggacg gctggcgcgg gctgaccttc
    38221 gcctcgccgt tcggggagct cgccctgctg ctcaacctca gctggctggc ggcggtcgtc
    38281 tatgccgacg cggtgttctc accgggcggc tcgacgtacg tggcggtggc cgccggcagc
    38341 cgggagacgt acgcggtggc caagaacgag gcgctgcccc ggtggttcgc cggggtgtcg
    38401 gagcggtccg gtgtcccgcg aagggccatg gctctcaact tcgcgctgag cgtcgtcatc
    38461 ctgctgccct ccagcgggtg gcgggacctc atcaccgtgg tcggcaccct ggccctgctg
    38521 acctacgcgc tgtgctccgt ggcggcgggc acgttccggg aggccgcgcc cgagcggctg
    38581 gcgggctggg tccgcggcct cggctggatc gcgccggcgg gcttcgtggt cgcctcggag
    38641 cttgtgcact ggtcggactg ggagaacctg cggatcgcgc tgcccgagtt gctcgccgcc
    38701 gtgctcctgt tcgccgtcct gcgccgccgt gacctcgacc tccgtgccga gctgcggacc
    38761 ggcgcgtggc tcctcggcta cctcgtgtgg ctgctggtca tgtcaggtct cggcagcttc
    38821 ggcgggatga acctgatccc ggcgccctgg gacacggtcg cggtggccct ctccgccctg
    38881 gccacctacc ggtggggcgt ccgctccggc gtggcgcacc tgcgccgctg acggcaggcc
    38941 ggccgcctga cggtgacctc cccggcccca cgaggcccct gagccgaacg gcatgagcgc
    39001 cgaagggccc gccggtgccg ccggcctcgc cgctcgcagc tccggggggc cggggtgagg
    39061 gcgcccccag ccgctctgta tagggtcatg cacggtgcga gacggatgaa tggcggcgag
    39121 ttccgagggg acgcgagaga tgacccacag cccggccggc aggctccagg ggctcttcga
    39181 gggccgtcgg ctgacgccca cgcagcgcag gatcgcccac tgcatggtgc gccacgccga
    39241 cgaggtgccg ttcctgtcca gcgtcgagct ggccgaactg gccggagtca gccagccctc
    39301 cgtcacgcgg ttcgcggtcg ccctcggctt cgacggctac ccggcgctcc ggcgcgacct
    39361 gcgtgagcgg gtgcccgccg cgcccgccgc ggccgccgag gccaacgggt accagcaggc
    39421 cgtcgagggt gagatcgcca acctgcggcg gctcgccgac ttcctcgccg accccggccc
    39481 gctggagcgg gccgggcgac tgctggccgg ctcgcggccg ctgccggtgc tgggactgcg
    39541 ggcggccgcc gcccaggcac gcggcttcgc ctatttcgcc gccaaggtcc acccggacgt
    39601 acggctgctc gacgagggcg gcaccatgct ggtcgaccgg atcgacgccg cccggctggc
    39661 cggtgcctcc gccctgctct gcttcgcact gccccgccac ccgcgcgagg tggtcgaggc
    39721 actggcgtac gccagggagc gcgggctgcg cgtggtgacc gtggccgact cggccttcgc
    39781 gccggtcgcc gcggaatcgg acgtgctcgt cccgggggcg gtggggaccg ggctcgcctt
    39841 cgacacggcc tgcgcgccga tgctgctggg ccgggtcctg ctggaggcga tgtgcgacgc
    39901 gctccccgac gcgcaggccc ggctggagcg gttcgacgcg cgcgccgccg accgggggct
    39961 gttcgccgag taggggcgga ggcgaccgtt tctcacccgc gtctcaggaa aggccggtaa
    40021 cctccgggcc cacatcggcc cccggcgtcc gggggcgacg cgtgaaggag gagcgggagt
    40081 tgagaggcgg agcacgggga ctggtacggg tggcggtggt ccagcgggcc ggagcggcac
    40141 ccctgtggtg gctcggagtg gtcgcggcgg gcgccgggct ggtcccggac gggctgaccg
    40201 gccgccgcat cggcgtcctc gcgggcgccc tgctgttcct gtcggcggcg gccctcgtca
    40261 ccctggtgcg cggcggccgg gccgccgcgc tcgccgagca cgccgtacgc gccgcccgct
    40321 ccgacgtcct ccaggcccgc tcggtgacgg tacgcaactg gcggcgcggc cacgcctggt
    40381 ggctcgcgct cgccttcgcc gccgccctcg gcagcgcctt cgccctgccc gcggccggcg
    40441 gcatgctgct ggccggctgg gggacggggc tgtggctgcg ggcccgcagg acgggacggg
    40501 tggaggagtc ccacgacgcc ctgctgtgga ccaccgccga cgcgctcggc cggggcgggg
    40561 gcgatccgct gggcgcgaag gccacccggt tgcggacgac cgggtcgcgc gcgggggacg
    40621 cgacgccggg cggcggcagg cggcgctgac cgcgccgggc gacgcgtacc cgtcgtacgg
    40681 gctcagacct ccagttcgga ctcgatccgg cggagctggt ggcgggccat cgccaggttg
    40741 gcgcggccgg cgtccagcac caggtagagg aagaggccgt tgccgccccg ggacttgagc
    40801 aggcggatca ggtggtactg gccgccgagg gtgatgagga tgtcctcgat ctcctccttc
    40861 agccccaggt gctccatggt gcggagcttg gcgcggacca cgtcggtgtt ccccgccgcc
    40921 gcgacctcca ggttgaagtc cttgccgccg ccgagagtgc ccagcgccat gccgctcgtg
    40981 tagtcgacga gggcgacgcc ggtggcgccc tcgatgacgc tcatcgcttc cttgagggac
    41041 gtttcggtgt tcgccatggg tgcagtcctc ttcttcctcg gttgcttgcc ttgggtggat
    41101 cgcttgcgtg ctgcgccgcc ggccgcggtg gccgggggct cggatgtggc tctggtacgg
    41161 ggcggggtca tacggggcgc cggggcaggc tgccgggcgt gccgggggac gcgcccgccg
    41221 ggggcggcgg cgggggagcg accgggcggg ccggaggccg gacgcggggg tactcggcag
    41281 gcggctgcgg ggtggccgca cggtccaggg cggcgtcgac cagggcgccg atccgggctc
    41341 cggcgcggcg gccctccaga tgcaggcggc ccacgttgat gcggtcctcg gcgagcaggg
    41401 tcagcaccgc cgaggagccc gccgcgtacg tcgccacgta gccctgctcg ccgcggacca
    41461 ggagttcacg gaaggagccg cggccggtgg cgtcggtcag gcggaccgcc acgccgaggg
    41521 cggcggcggt cagggcggcg aggctctccg cctcggtccc ggcggtgtcc tgggccagga
    41581 ccaggccgtc ggccgaggcc gccagggcgc ccgagagcag cgggacacgg gcccgcagcc
    41641 gctggagttc gtcgaggact tcccgctcgg cggccatcag ttgtctcctc tcggcacgct
    41701 gtcggcgcgc gcgtatcaca ggacctccag ggcgtctcgg agccggcgca gcagggcgat
    41761 gtccggatcg ggcgtcacct cggggaggac gggcgccccg gcgtgcgcgc cgggcgaggc
    41821 gtcctcggga cggccgtacg accggacggc gtccagcgcg cccgccgccg ccagccgccg
    41881 tacgtcgatc agcgtgtgga aggcggagcg gcccagtccg agggcgatcg cggctgccgt
    41941 ccgggtgccg tcgaccgcct ccaggaccgc gcggcggcgc ggcgtcagag gcaggtcggc
    42001 cccgtcggtg aggcgggcca ggggcgcggt gtcgaccgcg gcgtccggcc agatccggtc
    42061 cagcagttcg cggcggcgca gtgtctcgcg ctccaccgag cgggccggga ccgggtgcac
    42121 cgggccgatc cagtgcgaga cgccgtaccg gaagcgggcc ggggtgctgg tgggggccag
    42181 ggcgaagaag gcggcgtcgt acagggcgcc gaggtggcag agttccagcg cgccccccgg
    42241 cacccgaccg ctgtccacca ggtacgccgc gacgcgctgc cgcgccccgg cggccgccac
    42301 cgcctcccac cagcccgccc tggccagcgt gccgccggcc gtcagcagga cgtcgatgcc
    42361 cggggtcgcc ggggactccg cgtgcaccac ctggccgtcc gccaggtaga gcgtgccccg
    42421 gtcccgcatg agcgccccgg tggcccgctc gtcggcgagc cgccggagca tcggggagag
    42481 cgggggtaac gccgcggtgg aggagccggc ggaggtcatg ccaggaccag ccgatccgcc
    42541 agttcgccga ggcggatcct ggcgagcgcc agattgccct cggagcggtg cagccacagg
    42601 tggacgaaga cgctgctgtc gaagtcggtc tcgacgaaac ggaggatgtg gtacccggcc
    42661 cgggaggtga cgatgacgtc ctccacgccc ccgtccgcgg ccccctcggg ggaggccgcg
    42721 gcacgtaccg agtcctgggc gaaggcgggc tgttcggcgg ccatgcgggc gacctcggcg
    42781 gtctcggcgg cggtcgcctc gtggtcgtcg tgcggggact cgccgatggt gcccagggcg
    42841 aggccgctcg tccagtcgac gacggccgcg ccgcgggcgc cggggagttt catgatgtcg
    42901 agcaggcact cgtcgattcc gggcatgcgg gggttcctcc cggacgtggg gtgcggctgg
    42961 ggtgtgagca agaggctacg catggtggtg gaggcttggg gaagttctgg cattttccag
    43021 gggtacttgc gttcggagcg ctaaagttcg gcccctttgt tcacgggggt tgccgtggag
    43081 ggcggcagga ctgtatgggc atggccgagc aagggaacgc acgcccgggc cggctacggc
    43141 cgctctggcc ggttcacggc ccaccggtcc accggtccac cggtccaccg gtccaccggc
    43201 ccaccggtcc accggcccac ggccgagttg ggccgcggcg cgtccaggct tccgtggccc
    43261 acccgcccgt ccacctgccc gccccggcct ggcgggcgtc gcggccgagg cccggacgcc
    43321 cgcaacctgg gcggccgaaa cctgggcgcc cgaggcgcct gcgcctgccc tggaagccgc
    43381 ctgcggatca gccgagtcgt gggggccggc ccgccgccca cccgccacgg ggcggagtca
    43441 ggacgactcc cgtacgacga gttccgtcgg caggacgacg tgctgccggg gctgaccggg
    43501 gtcgtcgatc tccgccagga ggatccgggc catcgtgcgg ccgatcgcct cgaccggctg
    43561 gcgcacgctg gtgaggggcg ggttgctgtg ccgggcgacg acggagtcgt cgaagccgat
    43621 caccgccacg tcgtcgggga cccgccggcc ctggcggcgc agttccacca gcgcgccggc
    43681 cgccatgacg tccgaggcgg cgaacaccgc gtccagaccc ggctcgcgtt caagtagtga
    43741 acgcatcgcg gcctcgccgc cggcctcggt gaagtcggcg gaggccacca gcgtctccgc
    43801 cgcctcgacg ccctcgccgc gcagggcgtc ccgccagccg tcgaggcgac tgcgcgacac
    43861 gtccatgtcg agggggccgc tgatggtggc gacccgccgc cgcccccggg ccaccaagtg
    43921 ggcgacggcc gccgcggcgc cgccctcgtt gtcggcgcgg acatggctga gcggctcgcc
    43981 gtgggcgcgc cggccggcga ggacggtggg cagccccatg ttctccagca ggcccggcag
    44041 cgggtcgtgc tcgtgcaccg agaccagcag caccccgtcc acccggcgct cggcgaccga
    44101 ctcggtgagc tggtcgcgct cggcctggtc gcgtacgagg accagttgga gctggatccg
    44161 ccgctcggtg agaccggtgc tgacgccgcg gatgacggcg gagaagtagg gctccgagcc
    44221 cagccggctc tccgactcgg ggatgaccag ggcgacggag tccgtcctgc tggtcaccag
    44281 cccccgggcg accgagttgg gcacgtagtt cagctccgcg atggcggcga gcacggccga
    44341 cctggcctcg tcgctgacca gctccgaacc gttgatgacg cgggacaccg tggtccgtcc
    44401 cacgcccgca cgcgcggcga cggtcttgat cgtcgggcgt tgcctgctgc ccatgaagcc
    44461 tccctcgcgc caggtcggtc agaccgtgat ccgccgggcg gggcctggcc gtgacctgcc
    44521 gccgttcgcc tgcgcattct gccagaacgc ccctgcgggc gagggggccg gagggtggcg
    44581 gacggacatc ctcccgaaac aaagtcgcgt caacttcttg acagagcctt tcggtggcgg
    44641 ccagtcttcg agctcccgga gtgggcacgt tcccatcgtc atttgggaac gtacccacca
    44701 cgcaaatcgg ccctgcggga cagctacgcg ggctcgaacc ccggtgcgcg agcgccgctg
    44761 aggaggacta catggccaga acccgcagga agccgcgtac aagagtcgtc gccgccatct
    44821 ccgcggtgtc ggccctcggg ttgctcgtcg gctgctcagg cggtggtgag gggaccggcg
    44881 gcggccggaa ggacggcaag gtcaccatca gcatggggct gtacggcgtg atgggcttca
    44941 aggaggccgg gctgctcgac aagtacatgg aggagaaccc ggacgtcgtc gtcgaggcgg
    45001 agatcgcggg cgacgaacag acctactaca ccgcgctcca gacccatctg gccgccggca
    45061 gcgggctgaa ggacatccag ggcatagaga tcggccgggc caaggaactg gtcgacaccc
    45121 agaaggacaa gttctccgac ctgtccggcg tgaaggggac cgaccacttc ctgccgtgga
    45181 agcagagcca ggtcaccgcg gccgacgaca aggtcatcgg cctcggcacc gacatcggcc
    45241 cgatggcggt ctgctaccgc aaggacaagt tcgaggaggc gggcctgccc accgaccggg
    45301 acgaggtcgc caagttgtgg gagggcgact gggcgaagta cgtcgccgtc ggcgagagct
    45361 tcaagaaggg cgtcaagggc gacaaggtcg ccttcatgga cagtgccagc ggactgttca
    45421 acgccatgat ctacggcggc ccccagcagt tctacgacaa ggagggggag ctggtctacg
    45481 ccgacaaccc cgtcgtgaag gacgcctgga agctggcctc gaaggccgcc acgtccggcc
    45541 tcaccgccaa gctccgccag ttccagccgg gctgggaccc cgggctcgcc aacggcacct
    45601 tcgccaccgc cgtgtgcccg gcctggatgc tggcgcacat cagcgagaag gcgggcgagg
    45661 ccaacaaggg caagtgggac gtggccaagg cccccaaggg cgccaactgg ggcggctcgt
    45721 tcctcggggt gatggagaac agccccgtca agaaggaggc ccaggaactc gtcgcctggc
    45781 tcaccgcgcc cgagcagcag gcgttcctct tccagaagca gggctccttc ccctcgtccc
    45841 ggaccgccct ggaatcccct gaggtcgccg gcaccaagtc ggagtacttc aacgacgc
//
