LOCUS       NZ_JACHJQ010000003     20921 bp    DNA     linear   CON 27-SEP-2024
DEFINITION  Actinophytocola algeriensis strain CECT 8960 Ga0436956_03, whole
            genome shotgun sequence.
ACCESSION   NZ_JACHJQ010000003
VERSION     NZ_JACHJQ010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinophytocola algeriensis
  ORGANISM  Actinophytocola algeriensis
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae.
REFERENCE   1  (bases 1 to 1136783)
  AUTHORS   Whitman,W.
  TITLE     Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the
            genomes of soil and plant-associated and newly described type
            strains
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1136783)
  AUTHORS   Whitman,W., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2020) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 154.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014203735.1-RS_2024_09_27
            Annotation Date                   :: 09/27/2024 05:42:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,095
            CDSs (total)                      :: 9,030
            Genes (coding)                    :: 8,881
            CDSs (with protein)               :: 8,881
            Genes (RNA)                       :: 65
            rRNAs                             :: 3, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2, 2 (5S, 16S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 44 of 149
            Pseudo Genes (incomplete)         :: 120 of 149
            Pseudo Genes (internal stop)      :: 3 of 149
            Pseudo Genes (multiple problems)  :: 17 of 149
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:06:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 671831
            Orig. end                         :: 692752
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JACHJQ010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20921
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20921
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20921
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10921](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10921
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    239..254
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: medium, score: 24.49"
                     /tool="antismash"
     misc_feature    complement(406..422)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.18"
                     /tool="antismash"
     gene            complement(560..1474)
                     /locus_tag="FHR82_RS15520"
                     /old_locus_tag="FHR82_003157"
     CDS             complement(560..1474)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012782768.1"
                     /locus_tag="FHR82_RS15520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003157"
                     /product="ABC transporter permease"
                     /protein_id="WP_184811552.1"
                     /transl_table=11
                     /translation="MSAAEQEQAPPPPPSTRSWSRAREDIVEGFKQRELWGHLGWQDIK
                     QRYRRSVIGPLWITLSMAITAIGLGLLYSQLFQATIPTFLPYITVGFIVWNFINGCITE
                     GTDTFIRNEGLIKHLPAPLTVYALRTVWRLTLMFAHNLLVYVVILVIFWGSLTTSDYTI
                     TDGGNPQPGIGFGILLAIPAFVLLAVNGGWVAILFGIISTRYRDIPQVINSLISLLFFM
                     TPIVWTTDILTQRLPGSGDSDWKVLIAELNPLYHYVQLLRAPLIGNEQSWHHWAVVGGF
                     TVVGWGLAFVAMRNYRSRVSYWV"
     gene            1635..2264
                     /locus_tag="FHR82_RS15525"
                     /old_locus_tag="FHR82_003158"
     CDS             1635..2264
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012795673.1"
                     /locus_tag="FHR82_RS15525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003158"
                     /product="glycosyltransferase family 29 protein"
                     /protein_id="WP_184811077.1"
                     /transl_table=11
                     /translation="MRTLIDVYAEHPEPRTVAVVGNMPLPADEERAKAIDACDLVFRVN
                     GFVTDDPGAAPTVGSRTHVVVFNRALRATKYVFENYRRRLYLMVEPGRLHWEPDNLPGW
                     WPADLGLVPVNNAEVTLPLSDALGLPSRTEGTWSTTGTMAAWIARTCYPEAELLLTGYS
                     FIDDPNQTHWMHAAGDSCIVGPEHQIAAEGRLLDSWTKTGRTRLLR"
     gene            2275..2748
                     /locus_tag="FHR82_RS15530"
                     /old_locus_tag="FHR82_003159"
     CDS             2275..2748
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012795674.1"
                     /locus_tag="FHR82_RS15530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003159"
                     /product="hypothetical protein"
                     /protein_id="WP_225944026.1"
                     /transl_table=11
                     /translation="MRNNGFEGLRTLFGARPVVSDRIKRLIDFRINERIPAERLEEYYR
                     TVDRLAHDHTEVVEDMRRRINDLERRFNEVDKIQRWTHNELERIIPQVASQESQLESLR
                     EKIAAVPVGDQPQIDESRTLIDEIRREHSQIRVRLTAVAQYEDRLRKLEDRAE"
     gene            2900..3121
                     /locus_tag="FHR82_RS15535"
                     /old_locus_tag="FHR82_003160"
     CDS             2900..3121
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FHR82_RS15535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FHR82_003160"
                     /product="hypothetical protein"
                     /protein_id="WP_184811078.1"
                     /transl_table=11
                     /translation="MVDVQWWLSAYDNRVHAFGNEEAGRDFGEALCEHCVPNNKISCTD
                     DGERCLACLLIFGDLLADTLGEANWRAS"
     misc_feature    2921..2923
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3140..4189
                     /gene="pseI"
                     /locus_tag="FHR82_RS15540"
                     /old_locus_tag="FHR82_003161"
     CDS             3140..4189
                     /EC_number="2.5.1.97"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pseI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005452746.1"
                     /locus_tag="FHR82_RS15540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003161"
                     /product="pseudaminic acid synthase"
                     /protein_id="WP_184811079.1"
                     /transl_table=11
                     /translation="MREVRIGKHTIGADHRPFVIAEMSGNHNGDLDRALAIVDEVARSG
                     AQALKLQTYRADTITIDVDAPAFRISDDHSLWGGENLYSLYEKAHTPWEWHAPIFERAA
                     QQGLTVFSSPFDPTAIDLLESLDAPAYKIASAEIVDLPLVELAARTGKPLVISTGMANV
                     AEIHAAVETARRAGNDQLVVLGCTASYPADPADSNLRGIPLIRDTFDVVPGLSDHTMGI
                     GVPVAAVALGACVIEKHVTLKRADGGVDSEFSLEPLELAALVTETERAWQALGTTRIGP
                     KDSEREVSRLRRSLWVVEDVAEGDEVTAANVRSIRPSGGLAPADLGTVLGRRFRQAAPK
                     GTPLTWDLV"
     misc_feature    complement(4190..4201)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            4203..4733
                     /locus_tag="FHR82_RS15545"
                     /old_locus_tag="FHR82_003162"
     CDS             4203..4733
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034351.1"
                     /locus_tag="FHR82_RS15545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003162"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_184811080.1"
                     /transl_table=11
                     /translation="MLWPPAPLRTERLVLRESEARDRAAFIELFASPEVRTYLGGPRPR
                     AELERAVPEVPGRRPGVFVADLDGAMIGIITLDRRAAERPGHVHPDAGETELGYLFLPE
                     VWGRGYAAEACAAALGWFACERPGEPVVLCTQTANDRAVRLAAKLGFTEVERFEEFGAE
                     QWFGVWSPVTPSD"
     gene            complement(4740..5504)
                     /locus_tag="FHR82_RS15550"
                     /old_locus_tag="FHR82_003163"
     CDS             complement(4740..5504)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013775.5"
                     /locus_tag="FHR82_RS15550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003163"
                     /product="phosphotransferase enzyme family protein"
                     /protein_id="WP_184811081.1"
                     /sec_met_domain="APH (E-value: 1.4e-20, bitscore: 70.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLDLAPWGSPTVLERLGGHRNEVFRLEGGLVARRSRRSVASLDW
                     ELDLLDHLSRHGFLVPEVVRADGRAQVDGVVVQRWLPGREPTDWAPVVAELRRLHELTA
                     GWPPRPDFPGTRDLLTTDRGGDVDLTAMPPEAVETCRAAWRALDGPSTVVHGDPCAANI
                     RVDGDRVGFLDWDEARVDHPWLDLADIPGLDLPPAAHAAVNAWEAANGWLVEPHYARER
                     LAQLACGQPCGQHPGLWTTCVSASACGIQTCG"
     gene            complement(5561..6712)
                     /locus_tag="FHR82_RS15555"
                     /old_locus_tag="FHR82_003164"
     CDS             complement(5561..6712)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030637.1"
                     /locus_tag="FHR82_RS15555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003164"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_311771099.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.1e-110,
                     bitscore: 365.4, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 9.1e-07, bitscore:
                     24.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPYGRQSIVEEDIAAVAEVLRGDWLTTGPAVRRFEADLSALVGG
                     VPTVSVTSGTAALHVAYAAAGIGQGDEVVCAPMTFVATAATAIQQGATVVFADVSPETG
                     NLLPEAAAAAMTAKTRVVSSVDYAGHPVQVDELLKVAHDGGALLLEDAAHSIGGTWQRR
                     PVGALADLTTFSFFPTKNLTTAEGGAVATPNPDLARRAAQFRNHGLVRDKARMRYPDEG
                     GWHQEVHEFGLNYRLPDVLCALGSSQLRRLAWFKERRAEIHARYTAGLSDVDGVRTPVT
                     LPGADPMWHLYPLRVLDGRRRDLFDHLRAGGIGVQVNYIPVYWHPVFADLGYQRGMCPN
                     AERFYAEELSLPLFPDLSDDYVDRVIELVRKFFSPERSLRSEQ"
     gene            complement(6843..7826)
                     /gene="pseB"
                     /locus_tag="FHR82_RS15560"
                     /old_locus_tag="FHR82_003165"
     CDS             complement(6843..7826)
                     /EC_number="4.2.1.115"
                     /NRPS_PKS="Domain: NAD_binding_4 (10-130). E-value:
                     1.9e-09. Score: 28.9. Matches aSDomain:
                     nrpspksdomains_FHR82_RS15560_NAD_binding_4.1"
                     /codon_start=1
                     /gene="pseB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005450427.1"
                     /locus_tag="FHR82_RS15560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003165"
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase
                     (inverting)"
                     /protein_id="WP_184811083.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 3.2e-94,
                     bitscore: 311.4, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 4.9e-11, bitscore:
                     38.3, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALLEGAGILLTGGTGSFGKAFIDYALKHLDPRRLVILSRDELKQ
                     YEARQMFGDDPRLRWFIGDVRDRRRLERAMHDVDYVVHAAALKQVDTAEYNPFEFVQTN
                     ITGSQNVIEAAIDCGIQKVVALSTDKASSPINLYGATKLCADRLFISGNHYAAGHPTRF
                     SVVRYGNVMGSRGSVIPFFKSLADRGEALPITDLRMTRFWITLPQAVEFVVNSFDSMHG
                     GELYVPRIPSMRLVDLARVIAPNSPMKEVGIRPGEKLHEEMIAPDDSRRTLLLDDRYVV
                     MPHIAGWGYEPPAEGQAVPEGFAYRSDTNDLWLSDDDLRALVAQYG"
     aSDomain        complement(7437..7796)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FHR82_RS15560_NAD_binding_4.1"
                     /evalue="1.90E-09"
                     /label="FHR82_RS15560_NAD_binding_4.1"
                     /locus_tag="FHR82_RS15560"
                     /protein_end="130"
                     /protein_start="10"
                     /score="28.9"
                     /tool="antismash"
                     /translation="LTGGTGSFGKAFIDYALKHLDPRRLVILSRDELKQYEARQMFGDD
                     PRLRWFIGDVRDRRRLERAMHDVDYVVHAAALKQVDTAEYNPFEFVQTNITGSQNVIEA
                     AIDCGIQKVVALSTDK"
     CDS_motif       complement(7707..7799)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHR82_RS15560_0001"
                     /evalue="5.30E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="FHR82_RS15560"
                     /protein_end="40"
                     /protein_start="9"
                     /score="9.5"
                     /tool="antismash"
                     /translation="LLTGGTGSFGKAFIDYALKHLDPRRLVILSR"
     gene            7868..8605
                     /locus_tag="FHR82_RS15565"
                     /old_locus_tag="FHR82_003166"
     CDS             7868..8605
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012795679.1"
                     /locus_tag="FHR82_RS15565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003166"
                     /product="cytidylyltransferase domain-containing protein"
                     /protein_id="WP_184811084.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.9e-08, bitscore:
                     30.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPVRVNAVIQARLSSTRLPGKVLRPLGGRSVLSWVIRAAQETHN
                     LDTVILATSDDPTDDPVADEAARCGAVVVRGPLDDVLARYVKAVREHPCDAVVRLTADC
                     PLHDPAVIAQVVAVWRADPTLDHVSNFVVRRHPRGLDTELVRVAVLEEQARIATGGHRE
                     HVTSNIYTQPDVYRCGGVVPGVDNSDLRVTLDTEEDAKLLEGVVAELGDEVPSWQALVA
                     LLRSRPDLVALNADVEQNTTPTT"
     gene            8602..9942
                     /locus_tag="FHR82_RS15570"
                     /old_locus_tag="FHR82_003167"
     CDS             8602..9942
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024698.5"
                     /locus_tag="FHR82_RS15570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003167"
                     /product="bifunctional
                     UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose
                     hydrolase/GNAT family N-acetyltransferase"
                     /protein_id="WP_184811085.1"
                     /transl_table=11
                     /translation="MTRLLLRADATPSTGVGHLSRCVALATAARSRGWDVALCGSFTAG
                     RWLLGSLPVVASPEPADAVVVDHYGIGEFSADGLVVSMEDGGFGRRRADIVVDANLYAA
                     PRPDDGSPVVLRGPAYAPLRAEIRAARTARTARTAQRAGSVPPKVVVVMGGGAAPSSVA
                     AALSALRDTGVPAEVVAISAAPVPGFEVVPPTPELPALCASADLVVSAAGVTLLELCCI
                     GVPTALVRIADNQAAGYQAAVEQGVAAGLGADPRSHVPVLRTLLRDAAARKALGDKART
                     TVDGRGADRVLDAMGFDPTVRAATGADAALLLSWRNDEETRRWSRTTDPVSPADHEAWL
                     SRVLTDDDRWLLVAEHDGRPVGTVRFDRAGGAWEVSITVAPAARGRRLAVPMLLAAERA
                     LGPAVIRANVHGENAASLALFRRAGYRPVPSVSRSEWHWLEKSPSQE"
     gene            10001..10921
                     /locus_tag="FHR82_RS15575"
                     /old_locus_tag="FHR82_003168"
     CDS             10001..10921
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020667220.1"
                     /locus_tag="FHR82_RS15575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003168"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_184811086.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.8e-46, bitscore:
                     154.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNTLLSDVESRLREVLDGHAGATHLIDAGGKRLRPMLVILGAEF
                     GPRQDKVVDAAVLTELVHVGTLHHDDVMDQAPVRHGVPTANALWGNNRAILLGDLMLAR
                     AGELGAELGLPALRLQTTTLARLVRGQLMETVRPKSADPMAFCLEVMADKSASLIAMAA
                     ELGALVAEAPPSVCGALHIYGEHLGIAFQLVDDVLDIVGGESGKTPGTDLRAGVVTVPV
                     LHALAAGDAAADRLRVLLVTGTVTDPDLHAEALGLLRDGPGPSLTRADAGDHAELARAA
                     LADLPRGEAREVLDSLCDAVLERAK"
     gene            11066..11431
                     /locus_tag="FHR82_RS15580"
                     /old_locus_tag="FHR82_003169"
     CDS             11066..11431
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078170.1"
                     /locus_tag="FHR82_RS15580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003169"
                     /product="VOC family protein"
                     /protein_id="WP_184811087.1"
                     /transl_table=11
                     /translation="MPARFKDLVIDANDHHTLADWWCGAMGYVRKDEHEPPADGWMRPH
                     DWPVPIVDPHGAGPLFWIVPVPEKKTGKNRLHLDVFGDTQELLDAGATLLRRRDDEIEW
                     DVLADPEGNEFCVFTPR"
     gene            11428..12183
                     /locus_tag="FHR82_RS15585"
                     /old_locus_tag="FHR82_003170"
     CDS             11428..12183
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104742.1"
                     /locus_tag="FHR82_RS15585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003170"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_184811088.1"
                     /transl_table=11
                     /translation="MTALDIVIVVAAGLFAGGINSVVGSGTLVTFPVLLALGYPPVVAN
                     VSNSLGLVPGSIGGAVGYRRELKGQGSRLLRFGVVTAVGAVGGALLLLVLPPGAFEAVV
                     PALIVVALVLVLLQPLIAKRLAQREGDRHPHGGIPLLFGVFGCAVYGGYFGAAQGVILL
                     ALMGILVDDSLQRLNGVKNVTTAIANLVSGVVFVFVADVDWAVVGLLAGGSTIGGLIGA
                     RIGRRLRPIWLRAAIVVVGTVAIVQLLIR"
     misc_feature    12124..12126
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12301..12924
                     /locus_tag="FHR82_RS15590"
                     /old_locus_tag="FHR82_003171"
     CDS             12301..12924
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013672451.1"
                     /locus_tag="FHR82_RS15590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003171"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_225944027.1"
                     /transl_table=11
                     /translation="MTYAEPHGVVRGGVVVLHEERGMTEAMRDLITGLAAEGWLTVAPH
                     IYDGDSTEVDDLTALDRISELSGESVLADTDIAFGWLAQHGIDADRIGVVGFELGGAVA
                     LVVAASRAIGAAVSVGGGGILNPLSPGLPALVDAAPTLRCPWLGLYGDKVADEVALLRD
                     AAKRSETANDVVLYPAADHRFDIYPDTAVEAWQRVLNWFDAHLR"
     gene            12944..13717
                     /locus_tag="FHR82_RS15595"
                     /old_locus_tag="FHR82_003172"
     CDS             12944..13717
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025377.5"
                     /locus_tag="FHR82_RS15595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003172"
                     /product="ESX secretion-associated protein EspG"
                     /protein_id="WP_184811090.1"
                     /transl_table=11
                     /translation="MSATSLSHQEFDLLWEHLGFTERPYPLDVRSFGYTMDERAALREQ
                     VRQSLAHKGLHDGAEVAPALEEQLALLGRHTRSVDGRLSVGETLRVLAASDGRRGVLAA
                     QSDDEVRLAWVRNARLVPAVIALLPDRRPGPGGSARLPKEVFDAAVDEFAASGYVGLER
                     TLTNGGVTGRDLRTVTTLLESGRQGGGQLAANSVDQVGRRTRTSVLNWFDTEPGRYLVH
                     TEVTRDRVEWLTITPADTARVEQRLTEMAASLNQP"
     gene            13776..14216
                     /locus_tag="FHR82_RS15600"
                     /old_locus_tag="FHR82_003173"
     CDS             13776..14216
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FHR82_RS15600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FHR82_003173"
                     /product="hypothetical protein"
                     /protein_id="WP_184811091.1"
                     /transl_table=11
                     /translation="MSEPRAFPGAASGALAPVATKVGKVKEQALAGSLTIDLEVAKVIL
                     VQLGTLRARAAELVRDCVDLDTPLRFGDNWVGRIMSERLRMVAVDSDGGVTHVLTAFHQ
                     VLDDLEATVRFAAGMYETSDESAADDLRRAVGQFGVTVEEES"
     gene            14213..15307
                     /locus_tag="FHR82_RS47415"
                     /old_locus_tag="FHR82_003174"
     CDS             14213..15307
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013021.5"
                     /locus_tag="FHR82_RS47415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003174"
                     /product="PPE domain-containing protein"
                     /protein_id="WP_184811092.1"
                     /transl_table=11
                     /translation="MSEGIMIGGCYPPSWPRPPKPPVDEPVPESLDETVEWMTWSHPEL
                     YRMVHDGIDLTGAMSVSATWARLGDELADMADELSKLLFTTSQAWEGEAAELAKESVSA
                     LSEWSRETAIRATEVCACVTVQVDNVATARNDMPPPPYPVLPTPTPLPSQVTAFTNGGF
                     DTATPLVVDPLVYTTQERELHEQAARTMERFQANSRDVYATVPQFAPPSLRKVPYGPPT
                     EPPQPPPPPQPPQPPVPPPVPRVPGGGPGPGAGGGPVSGGGPGAAGPGTPGRAPATAPL
                     APGGGAGTGEPAARPAAASAVPVRQGGQAPGMAGGMPMGGGGGSGRGEDIERRNKYVEE
                     DPDIWGASDERVMPPVIGEVNRRA"
     gene            15300..16052
                     /locus_tag="FHR82_RS15610"
                     /old_locus_tag="FHR82_003175"
     CDS             15300..16052
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025377.5"
                     /locus_tag="FHR82_RS15610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003175"
                     /product="ESX secretion-associated protein EspG"
                     /protein_id="WP_184811093.1"
                     /transl_table=11
                     /translation="MRDPGSGWIQLSVVELYLLWSAMGLGPTPEVLDVLHVGRTKARRA
                     ELAEESSRDLAARDLGTVAAPARDLAGMLRSLGNPSASLDMRVYGTGSPLFAFAAVGPS
                     GAAIAARVGDEVRLGAVRPTALASSLLGSLTHLPAAADRPANVSAADYDAACAQGAAEG
                     ISGFTRVLHAAGVRAEEVSTLTQALTSRTGGGQLGATGRARAYSLVNWLDTPDGRYALR
                     RNGSWITLTPADTARLTTMAEEMLTDVR"
     misc_feature    16054..16069
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.52"
                     /tool="antismash"
     misc_feature    16064..16078
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.52"
                     /tool="antismash"
     gene            16157..16564
                     /locus_tag="FHR82_RS15615"
                     /old_locus_tag="FHR82_003176"
     CDS             16157..16564
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007512669.1"
                     /locus_tag="FHR82_RS15615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003176"
                     /product="YciI family protein"
                     /protein_id="WP_184811094.1"
                     /transl_table=11
                     /translation="MAKYLLLKHYRGAPAAVNDVPMAEWTPEEISAHVKYMDDFAARLE
                     ETGEFVDSQALSPVGTFVRYDGEGRPPVTDGPFAETKDLIAGWMVIDVDTYDRAIELAG
                     ELSAAPGAGGKPIHEWLELRPFYGSAPTITE"
     gene            16567..17709
                     /locus_tag="FHR82_RS15620"
                     /old_locus_tag="FHR82_003177"
     CDS             16567..17709
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009948507.1"
                     /locus_tag="FHR82_RS15620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003177"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_184811554.1"
                     /transl_table=11
                     /translation="MDEALLRSLTPNVLGILVRRGADFAAAEDAVQEALIEALRVWPAD
                     PPRDPKGWLVTVSWRKFLDATRADAARRRREDAGELVAEPAPEPVPAVDDTLQLYFLCA
                     HPSLSPSAAVALTLRAVGGLTTRQIAQAYLVPEATMGQRISRAKRTVSGVRFDQPGDVA
                     TVLRVLYLVFNEGYSGDVDLAAEAIRLTRGLAAAIDHPEVAGLLALMLLHHARRAGRTT
                     PDGGLVPLAEQDRGRWDTAMIAEGVGILQAALARDRLGEFQAQAAIAALHADAPTAEET
                     DWVQIVEWYDELVRLTDSPVVLLNRAVAVGEADGPRAGLAALAALDDSLPRHAAVAAYL
                     HERDGDLAAAARLYVEAASKAPNLAECEYLTRQAARLNNR"
     gene            complement(17714..17995)
                     /locus_tag="FHR82_RS15625"
                     /old_locus_tag="FHR82_003178"
     CDS             complement(17714..17995)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016698174.1"
                     /locus_tag="FHR82_RS15625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003178"
                     /product="DUF4287 domain-containing protein"
                     /protein_id="WP_184811095.1"
                     /transl_table=11
                     /translation="MSFQAYLDGIEKKTGKTPAELLAEAGARGYDATTRAGVVLEWLKT
                     DYDLGRGHGMALCHVLKNGTEISDKHVGGTGTHRDPSATLRIDGLANR"
     misc_feature    complement(18062..18075)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.63"
                     /tool="antismash"
     misc_feature    complement(18065..18079)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.51"
                     /tool="antismash"
     gene            complement(18101..18760)
                     /locus_tag="FHR82_RS15630"
                     /old_locus_tag="FHR82_003179"
     CDS             complement(18101..18760)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016699539.1"
                     /locus_tag="FHR82_RS15630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003179"
                     /product="response regulator transcription factor"
                     /protein_id="WP_184811096.1"
                     /transl_table=11
                     /translation="MTVDVLIVDDDPLVRTGLTMMLGGAPDIRVVAEAGDGAEVLALVD
                     RHRPHVVLMDIRMPTVDGLTATEALRKRRDAPEVLVLTTFDADRHVLRALRAGAAGFLL
                     KDTPPAQIVAAVRQVAEGTPVLSPVVMKRLVARVAATETETRGTRAATRLAVLNDRERA
                     VAVEVGKGRSNAEIGTALHLSVPTVKTHVSSALTKLDLNNRVQIAILVHDAGLLPD"
     gene            complement(18757..19872)
                     /locus_tag="FHR82_RS15635"
                     /old_locus_tag="FHR82_003180"
     CDS             complement(18757..19872)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010226143.1"
                     /locus_tag="FHR82_RS15635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_003180"
                     /product="sensor histidine kinase"
                     /protein_id="WP_184811097.1"
                     /transl_table=11
                     /translation="MRRSLRDWSVDIGLFMFAVLYGLLVVAMRVETGSAPRQEWLFALD
                     QLVGVAGAGLLWLRRRWPVGVAAALMAVACVSELVGGAAMVALFTVAVHRSLRVTAVLF
                     AAGLASTCVFLLLRPAPDEPLAFSLGFGFAVQCAVVGWGLVVRHRRELVLSLRERAARA
                     ETEARLRADRAQLQAREAIAREMHDVLGHRLSLLSVHAGALEYRPDAPAADIARAAGVI
                     RESAHQALQDLREVIGVLRAPVQELPQPTFADVPALVAESARAGMPVVLRNEITAEMPD
                     TLGRTVYRIVQESLTNARKHAAGSTVDISVRDADGLRVEIVNTAGEPGEPGGGQGLAGL
                     RERVALAGGRVDAGPEPGGGWRVSAWLPWPA"
     misc_feature    complement(20161..20176)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.12"
                     /tool="antismash"
     misc_feature    complement(20161..20176)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.33"
                     /tool="antismash"
ORIGIN
        1 cgcgccgatg ccctcgtcca gcagcaggat ctccgggtcg atcgacgtga ccacgcccag
       61 cgcgaggcgg acgcgcatgc ccgtggagta cgtccgcagc ggcatctgca ggtagtcgcc
      121 gagctcggtg aactcggtga tgtcgtcgac ccgcttctcc atctgcttgc gggtcatgcc
      181 gaggaacagg ccgcggatca tgatgttctc gaggccggag atctccggat ccatgccgac
      241 gccgaggtcg aacaccggcg cgaccttgcc gacgatccgc gacgagcccc tggtcggctc
      301 gtagatgccc gccagcagcc gcagcagcgt cgacttgccc gcgccgttgt ggccgacgag
      361 ccccacgcgg tcgccttcct tcagcgacag cgtgatgtcg tgcagtgcct cgatgatcgg
      421 caccttctgc tcggtgccga tcttgccgcc gaccttgccg aggacggcct tcttcaggga
      481 gcgggtcttc gcgtcgaaga tcgggaagtc gaccgaggcg tcccagacgt tgatgctgac
      541 catgccgtta tcgcctcact cagacccagt aggaaacgcg cgaacggtag ttgcgcatgg
      601 ccacgaaggc caggccccac cccacaacgg taaacccgcc gacgaccgcc cagtggtgcc
      661 aactctgctc gttgccgatc agcggcgcgc gcagcagctg cacgtagtgg tagagcgggt
      721 tcagctcggc gatcagcacc ttccagtcgc tgtcacccga gccgggcagg cgctgcgtga
      781 ggatgtcggt ggtccacacg atcggcgtca tgaagaacag caacgagatc aggctgttga
      841 tgacctgggg gatgtcgcgg tagcgcgtgg agatgatgcc gaagaggatc gcgacccacc
      901 cgccgttgac cgcgagcagc acgaacgcgg gaatggcgag caggatgccg aaaccgatgc
      961 ccggctgcgg gttgccgccg tcggtgatcg tgtagtccga cgtggtcagc gagccccaga
     1021 agatgacgag gatgaccacg tacacgagga ggttgtgggc gaacatcagc gtgagccgcc
     1081 acaccgtgcg cagtgcgtac acggtcagcg gcgcgggaag gtgcttgatg agaccttcgt
     1141 tgcggatgaa ggtgtccgtg ccctcggtga tgcacccgtt gatgaagttc cacacgatga
     1201 agccgaccgt gatgtacggc aggaaggtcg ggatcgtcgc ctggaacagc tgggagtaga
     1261 gcagaccgag cccgatcgcg gtgatggcca tcgacagcgt gatccacagt ggtccgatga
     1321 ccgacctgcg gtagcgctgt ttgatgtcct gccacccgag atgcccccac agctcacgct
     1381 gtttgaagcc ctcgacgatg tcctcccgcg cacgcgacca gctacgggtc gaggggggag
     1441 gtgggggtgc ctgctcctgc tcggcagcgc tcattactga cacggctgtc gagactaccg
     1501 gcgggcactg cgcgtgccgc aggggccgcg cttcgcacag tgttgtcaca ccgagacccc
     1561 gcgcgcgaaa gaagatcgtt cgcgtcctgg taacttctgc gctcatggtc gacgtcgccc
     1621 ctgtgcagag cgtcatgcgc acgctcattg acgtctatgc cgaacacccg gaaccacgga
     1681 ccgtcgcggt cgtcggcaac atgccgctgc ccgcggacga ggagcgggcc aaggccatcg
     1741 acgcatgcga cctggtgttc cgggtcaacg ggttcgtcac ggacgaccct ggtgccgccc
     1801 cgactgtggg cagtcgcaca cacgtggtgg tgttcaaccg tgcgctgcgc gccaccaagt
     1861 acgtgttcga gaactaccgc aggcggctgt acctcatggt cgagccgggc cgtctgcact
     1921 gggaaccgga caacctgccc ggctggtggc cggcggacct ggggctcgtg ccggtcaaca
     1981 acgccgaggt gacgctgccg ctgtcggacg cgctcggcct gccgagccgc accgagggca
     2041 cgtggtcgac gaccggcacg atggccgcct ggatcgcacg gacctgctat ccggaggctg
     2101 aactcctgct gaccgggtac tcgttcatcg acgacccgaa ccagacgcac tggatgcacg
     2161 ccgccggtga ctcctgcatc gtcgggcccg agcaccagat cgccgccgag gggcggctgc
     2221 tcgactcgtg gaccaagacc ggccgcacca ggctgcttcg ctgagggaaa cacattgcgc
     2281 aacaacggtt ttgagggtct ccgcacgctg ttcggggccc gtccggtcgt gtcggaccgg
     2341 atcaagcggc tgatcgactt ccggatcaac gagcgcatcc cggccgagcg cctcgaggag
     2401 tactaccgga ccgtagaccg gctcgcgcac gaccacaccg aggtcgtgga ggacatgcgc
     2461 agacggatca acgacctcga gcgccgcttc aacgaggtcg acaagatcca gcgctggacg
     2521 cacaacgagc tcgagcgcat catcccgcag gtcgcgtcgc aggagtccca gctcgagtcg
     2581 ctgcgcgaga agatcgccgc ggtgccggtc ggcgaccagc cgcagatcga cgagtcccgc
     2641 acgctgatcg acgagatccg ccgggagcac agccagatcc gggtgcgcct caccgcggtg
     2701 gcccagtacg aggaccgcct ccgcaagctc gaagatcgcg cggagtagcc gtcagggccc
     2761 ggacatcacg ttccgttgcc attcacagtt taacgttcaa gtgggaattg ttgactggtt
     2821 gtctccatcg gtcaactctg ttgcctgtta ctccattcgt ggaccctgat gagtgggcac
     2881 aggcgcggag gtcggggtca tggtggacgt ccagtggtgg ttatctgcgt acgacaaccg
     2941 ggtgcacgcg ttcggcaacg aggaagccgg ccgcgatttc ggggaagcac tgtgtgagca
     3001 ctgcgtaccg aacaacaaga tctcctgcac cgacgacggc gaacgatgtc tcgcgtgctt
     3061 gctgatcttc ggtgacctgc tcgcggacac cttgggagag gccaactggc gcgcgtccta
     3121 ggcccggtac gttgggccca tgcgtgaagt caggatcggc aagcacacga tcggcgcgga
     3181 ccaccggccg ttcgtcatcg ccgagatgtc cgggaaccac aacggtgacc tggaccgtgc
     3241 gctggcgatc gtcgacgagg tcgccaggtc cggtgcgcag gcgctgaagc tgcagaccta
     3301 ccgcgccgac acgatcacca tcgacgtcga cgcgcccgcc ttccgcatct ccgacgacca
     3361 ctcgctgtgg ggcggggaga acctctactc gctgtacgag aaggcccaca cgccgtggga
     3421 gtggcacgcg ccgatcttcg agcgcgccgc ccagcagggc ctcaccgtct tctccagccc
     3481 gttcgacccg accgccatcg acctgctcga gtcgctcgac gcgcccgcct acaagatcgc
     3541 ctccgccgag atcgtggacc tgccgctcgt cgagctggcc gcccggaccg ggaaaccgct
     3601 ggtcatctcc accggcatgg cgaacgtcgc cgagatccac gccgccgtcg agaccgcccg
     3661 ccgcgcgggc aacgaccagc tggtcgtcct gggctgcacc gcgtcctacc cggccgatcc
     3721 ggccgacagc aacctgcggg gcatcccgct catccgcgac acgttcgacg tggtcccggg
     3781 cctgtccgac cacaccatgg gcatcggcgt gccggtcgcc gcggtggcgc tcggggcgtg
     3841 cgtgatcgag aagcacgtga cgctcaagcg cgccgacggc ggcgtggaca gcgagttctc
     3901 gctggagccc ctggagctgg ccgcgctggt cacggagacc gagcgggcct ggcaggcact
     3961 cggcacgacc cgcatcggcc cgaaggacag cgagcgcgag gtcagcaggc tgcggcggtc
     4021 gctgtgggtg gtcgaggacg tcgccgaggg tgacgaggtg acggccgcga acgtccggtc
     4081 gatccggccg tcaggtgggc tcgcccccgc cgacctgggg accgtgctgg gccgccggtt
     4141 ccgccaggcc gcgccgaagg ggaccccgct cacctgggac ctggtctagg cgttctcttc
     4201 ccgtgctctg gccacctgcc ccgttgcgga ccgaacggct cgtgctccgc gagtcggagg
     4261 cccgggaccg tgcggcgttc atcgagctgt tcgcctcgcc ggaggtgcgc acctacctcg
     4321 gtggtcctcg accgcgtgcc gagctcgaac gcgcggtgcc cgaggtgccc ggccggcgtc
     4381 ccggcgtttt cgtcgccgac ctcgacggcg cgatgatcgg catcatcacg ctcgaccggc
     4441 gcgccgcgga gcgtccgggc cacgtccacc cggacgccgg ggagaccgag ctcggctacc
     4501 tgttcctgcc ggaggtgtgg ggacgcgggt acgccgccga ggcgtgcgcc gcggcactcg
     4561 ggtggttcgc ctgcgagcgt ccgggcgaac cggtggtgct ctgcacccag accgccaacg
     4621 accgcgcggt gcgcctcgcg gcgaagctgg ggttcaccga ggtggagcgg ttcgaggagt
     4681 tcggcgccga gcagtggttc ggcgtgtggt ccccggtcac gccgtccgat tgagccaggt
     4741 tatccacagg tttgaatccc gcaagcgctt gctgacacac acgttgtcca caggccggga
     4801 tgttgtccac agggttgtcc acaggccagc tgtgcgagcc gttcgcgggc gtagtgcggc
     4861 tcgaccagcc agccgttggc ggcttcccac gcgttgacgg cggcgtgggc ggccggtggg
     4921 aggtccaggc ccgggatgtc cgcgaggtcg agccacgggt ggtcgacgcg ggcctcgtcc
     4981 cagtcgagga agccgacgcg gtcgccgtcg acgcggatgt tcgcggcgca cggatcgccg
     5041 tggacgaccg tcgacgggcc gtcgagggcc cgccacgcgg ctcggcaggt ctcgacggcc
     5101 tcgggtggca tcgcggtcag gtcgacgtcg ccgccgcggt cggtggtcaa caggtcgcgg
     5161 gtgccgggga agtccgggcg cggcggccag cccgcggtca gctcgtggag gcgccgcagc
     5221 tcggccacca ccggcgccca gtcggtcggc tcacggccgg ggagccagcg ctgcacgacc
     5281 acaccgtcca cctgcgcccg cccgtccgca cgcaccacct cgggcacgag gaaaccgtgg
     5341 cgcgacaggt ggtccagcag gtccagctcc cagtcgaggg acgcgacgga tcggcgggat
     5401 cggcgtgcca cgaggccgcc ttcgagacgg aacacctcgt tgcggtgccc accgagccgc
     5461 tccagcaccg tgggagagcc ccacggggcg aggtccaggg tcatgttcgc tcgcaaccct
     5521 tgctcggcat cactgttcgc tccgcaagct ccgctcggca tcactgttcg ctccgcaagc
     5581 tccgctcagg agagaagaac ttcctcacca gctcgatcac ccggtccacg tagtcgtccg
     5641 acaggtccgg gaacagcggc agcgacagct cctccgcgta gaaccgctcc gcgttcgggc
     5701 acatcccgcg ctggtagccg aggtcggcga acaccgggtg ccagtacacc gggatgtagt
     5761 tcacctgcac cccgatccca cccgcacgca ggtggtcgaa caggtcgcgg cggcgcccgt
     5821 ccagcacccg caacgggtac aggtgccaca tcgggtccgc gcccggcagc gtcaccggcg
     5881 tccgaacgcc gtccacatcg gacagcccgg cggtgtagcg ggcgtggatc tccgcgcgcc
     5941 gctccttgaa ccacgcgagc cgccgcagct ggctggaacc caaggcgcac aacacgtccg
     6001 gcagccggta gttcaggccg aactcgtgca cctcctggtg ccagccgccc tcgtccgggt
     6061 accgcatccg cgccttgtcg cgcaccagcc cgtggttgcg gaactgcgcc gcccgccgcg
     6121 cgaggtccgg gttcggcgtc gcgaccgcgc cgccctcggc ggtcgtcagg ttcttggtgg
     6181 ggaagaagga gaacgtcgtc aggtccgcca gagcgccgac cgggcggcgt tgccacgtgc
     6241 cgccgatcga gtgcgccgcg tcctccagga gcagcgcgcc gccgtcgtgc gcgaccttga
     6301 gcagctcgtc gacctgcacc gggtgcccgg cgtagtcgac cgaggacacc acgcgtgtct
     6361 tcgcggtcat cgccgccgcg gcggcctccg gcaggaggtt cccggtctcc ggcgacacgt
     6421 ccgcgaacac gaccgtcgcg ccctgctgga tcgcggtcgc ggcggtcgcg acgaacgtca
     6481 tcggcgcgca cacgacctcg tcgccctggc cgatgcccgc cgccgcgtac gcgacgtgca
     6541 gagccgcggt ccccgaggtc accgacaccg tcggcacgcc gccgaccagc gcggacaggt
     6601 ccgcctcgaa ccggcgcacg gccggtccgg tggtcagcca gtcaccgcgc aggacctccg
     6661 cgaccgcggc gatgtcctcc tcgacgatcg actgccgtcc atacgggagc acgtccgcat
     6721 cactggtcgc tgcgctcctc cgctcagacg ccgtcttccc tcctacgctg ctcgctcgcc
     6781 cgtggccggg ctccctgcgc tgctcgtcag tccagacgac gcccgctccg tcgctccgct
     6841 cctcacccat actgcgccac caacgcccgc aggtcatcgt ccgagagcca caggtcgttg
     6901 gtgtccgacc ggtacgcgaa gccctccggc accgcctggc cctcggcggg cggctcgtaa
     6961 ccccagcccg cgatgtgcgg catcacgacg taccggtcgt cgagcaggag cgtcctgcgc
     7021 gagtcgtccg gggcgatcat ctcctcgtgg agcttctcgc caggccggat gccgacctcc
     7081 ttcatggggc tgttcggcgc gatcacgcgg gccaggtcca ccagccgcat gctggggatc
     7141 ctcggcacgt acagctcgcc gccgtgcatc gagtcgaacg agttgaccac gaactccacg
     7201 gcctgcggca gcgtgatcca gaagcgggtc atgcgcaggt cggtgatcgg cagcgcctca
     7261 ccgcggtcgg ccagcgactt gaagaacggg atgaccgacc cgcgtgagcc catcacgttg
     7321 ccgtacctga ccaccgagaa ccgggtcggg tgacccgccg cgtagtggtt gccggagatg
     7381 aacagccggt ccgcgcacag cttcgtcgcg ccgtacaggt tgatggggct ggacgccttg
     7441 tcggtcgaca gcgccacgac cttctggatg ccgcagtcga tggccgcctc gatcacgttc
     7501 tgcgacccgg tgatgttggt ctgcacgaac tcgaacgggt tgtactcggc cgtgtcgacc
     7561 tgcttgagcg cggcggcgtg caccacgtag tccacgtcgt gcatggcgcg ctcgaggcgc
     7621 ctgcggtcgc ggacgtcgcc gatgaaccag cgcagccggg ggtcgtcgcc gaacatctgg
     7681 cgggcctcgt actgtttcag ctcgtcgcgg gacaggatca ccagacgccg tgggtccagg
     7741 tgcttcaggg cgtagtcgat gaacgccttg ccgaaggacc ccgtcccgcc cgtgagcagg
     7801 atgccagccc cttcgagcag cgccatggtc ttacctccgc ggtctgggtc gtcaccggtg
     7861 cgccatcatg gcacccgtgc gagtcaacgc ggtcatccag gcacggttgt cctccacccg
     7921 gctgcccggc aaagtgctcc ggccgctggg cggcaggagc gtgctgagct gggtcatccg
     7981 cgccgcccag gagacgcaca acctcgacac cgtgatcctc gcgacgtccg acgaccccac
     8041 ggacgacccg gtggccgacg aggccgcccg ctgcggtgcc gtggtcgtcc gtggcccgct
     8101 ggacgacgtg ctggccagat acgtgaaggc cgtccgcgag cacccgtgcg acgcggtggt
     8161 acggctcacg gccgactgcc cgctgcacga cccggcggtg atcgcgcagg tcgtggccgt
     8221 gtggcgggcc gacccgacgc tggaccacgt gtcgaacttc gtcgtgcgcc gccacccgcg
     8281 cggcctggac accgagctgg tacgggtcgc ggtgctggag gaacaggcac gcatcgcgac
     8341 cggcggccac cgcgagcacg tgacgtcgaa catctacacg cagcccgacg tgtaccggtg
     8401 cggcggcgtg gtgcccgggg tggacaactc cgacctgcgc gtcacgctgg acaccgagga
     8461 ggacgcgaag ctcctggaag gggtcgtggc ggagctcggc gacgaggtgc cgtcgtggca
     8521 ggcgctggtc gcgctgctgc ggtcccggcc ggacctggtg gcgctgaacg cggacgtcga
     8581 gcagaacacc acgcccacga catgacgagg ctgctgctgc gcgcggacgc caccccgtcg
     8641 acgggggtcg gtcacctgtc ccgctgcgtg gcgctggcga cggcggcccg gtcccgcggc
     8701 tgggacgtgg cgctgtgcgg atcgttcacc gcgggccggt ggctgctcgg atcgctcccg
     8761 gtcgtggctt ctcccgagcc cgctgacgcg gtcgtggtcg accactacgg catcggcgag
     8821 ttcagtgccg acggtctcgt ggtgtccatg gaggacggcg ggttcgggcg gcggcgcgcg
     8881 gacatcgtgg tggacgcgaa cctgtacgcg gcaccgcgcc cggacgacgg gtcgccggtg
     8941 gtgctgaggg ggcccgcgta cgcgccgctg cgtgcggaga tccgggcggc acggacagca
     9001 cggacggcac ggacggcaca gcgcgcgggt tcggtgccgc cgaaggtcgt ggtcgtgatg
     9061 ggtggcggcg cggccccgtc gtcggtggcg gcggcgctgt ccgcgctgcg tgacacgggg
     9121 gtgcccgctg aggtggtggc gatctcggcc gcgccggtgc cgggtttcga ggtcgtgccg
     9181 ccgacccccg agctgcccgc gttgtgcgcg tcggcggacc tggtggtgag cgcggccggc
     9241 gtgacgttgc tggagctgtg ctgcatcggg gtgccgaccg cgctggtgcg gatcgcggac
     9301 aaccaggcgg ccggctatca ggcggcggtg gagcagggcg tggcggcggg cctcggcgcc
     9361 gacccgcgat cgcacgtgcc ggtgctgcgg acgctgctgc gggacgccgc cgcgcggaaa
     9421 gcgctggggg acaaggcaag gacgactgtc gacggcaggg gagcggaccg cgtcctcgac
     9481 gcgatgggct tcgacccgac agtgcgtgcc gccaccgggg cggacgcggc gctgctgctg
     9541 tcgtggcgga acgacgagga gacccgccgc tggtcacgca ccacggaccc ggtctccccg
     9601 gccgaccacg aggcgtggct gtcccgcgtg ctgaccgatg acgaccgatg gctgctggtg
     9661 gcggagcacg acggccgtcc ggtggggacg gtgcgtttcg accgcgcggg cggggcgtgg
     9721 gaggtcagca tcacggtggc gcccgcagca cgcggccgga ggctggcggt accgatgctg
     9781 ctggcggccg aacgggcact gggcccggcg gtgatccgcg cgaacgtgca cggtgagaac
     9841 gccgcgtcgc tggccctgtt ccgccgcgcg ggctaccggc cggtgccgtc cgtgtcgcgc
     9901 tcggagtggc actggctgga gaaatctccc tctcaggagt gagcgcgttc ggccgcaggc
     9961 gggatctgcc gcggtggtcc ccggcgggaa gctcgacagc atggggaaca cgcttctgtc
    10021 cgatgtcgaa agccggctgc gcgaggtcct ggacgggcac gcgggcgcca cccacctcat
    10081 cgacgcgggt ggcaagcggc tgcgcccgat gctcgtcatc ctgggggccg agttcggccc
    10141 gcgccaggac aaggtggtgg acgccgcggt gctcacggag ctggtccacg tcggcacgct
    10201 gcaccacgac gacgtgatgg accaggcccc ggtccgccac ggggtcccga cggcgaacgc
    10261 gctgtggggc aacaaccggg cgatcctgct gggtgacctg atgctggcca gggccgggga
    10321 gctgggtgcg gagcttggcc tgcccgcgct gcgcctgcag accaccacac tggccaggct
    10381 ggtccgaggc cagctgatgg agacggtccg cccgaaatcg gccgacccga tggcgttctg
    10441 cctggaggtc atggccgaca agtcggcgtc cctgatcgcg atggccgcgg agctgggcgc
    10501 cctggtggcg gaggcgcccc cgtcggtctg cggcgcgttg cacatctacg gcgaacacct
    10561 gggcatcgcg ttccagctgg tggacgacgt actggacatc gtcggtggcg agtcggggaa
    10621 gactcccggc accgacctgc gagcgggggt ggtgaccgtg cccgtgctgc acgcgctggc
    10681 cgcgggcgat gccgcggccg accggctgcg cgtgctgctg gtcacgggca cggtcaccga
    10741 cccggacctg cacgccgaag cgctcgggct gctgcgggac ggccccggcc cgtcgctgac
    10801 tcgcgccgac gccggcgacc acgcggagct ggcgcgggcg gcgctggccg atctgccccg
    10861 gggcgaggcc cgcgaggtgc tggactcctt gtgcgacgcc gtgctggaga gagcgaagtg
    10921 agtaccggct gacgcctgtg gacaacgcac cgtccactct ggtccgcacc acgtcgggtg
    10981 ccggttggca agtggggtgt gacgtggtcc tcgaccaggg cgtatggcac gcgccacggt
    11041 cggcggcccg tgcgaccatg ccgcaatgcc agcacgtttc aaggacctgg tcatcgacgc
    11101 gaacgaccac cacacgctcg ccgactggtg gtgtggcgcg atggggtacg tgcgcaagga
    11161 cgagcacgag ccgcctgccg acgggtggat gcggccgcac gactggccgg tgccgatcgt
    11221 cgacccgcac ggtgccggcc cgctgttctg gatcgtgccg gtgccggaga agaagacggg
    11281 caagaaccgg ttgcacctgg acgtgttcgg ggacacccag gaactcctcg acgcgggcgc
    11341 gaccctcctg cgccgccggg acgacgagat cgagtgggac gtgctcgccg atcccgaggg
    11401 caacgagttc tgcgtgttca caccgcgttg accgcgctcg acatcgtcat cgtcgtcgcg
    11461 gcggggttgt tcgcgggcgg catcaactcc gtggtcgggt ccggcacgct cgtcaccttt
    11521 cccgtgctgc tggcgctcgg gtatccgccg gtggtggcga acgtctccaa cagcctcggg
    11581 ctcgtgccgg gatccatcgg cggtgccgtc ggctaccggc gggagctgaa ggggcagggc
    11641 tcgcggctgc tgcggttcgg cgtcgtgacc gcggtcgggg cggtcggcgg ggccctgctg
    11701 ctgctcgtcc tgccgcccgg cgcgttcgaa gccgtcgtgc ccgcgctgat cgtcgtcgcg
    11761 ctcgtactcg tcctgctgca gccgctcatc gcgaagcgcc tcgcccagcg cgagggcgac
    11821 cggcatccgc acgggggcat cccgttgctg ttcggggtgt tcggctgcgc cgtgtacggc
    11881 ggctacttcg gcgcggcgca gggcgtcatc ctgctggcgc tcatgggcat cctggtggac
    11941 gattcgctgc aacggctcaa cggcgtcaag aacgtgacca ccgcgatcgc gaacctcgtg
    12001 tccggggtgg tgttcgtgtt cgtggccgat gtggactggg cggtcgtggg tctgctcgcg
    12061 ggtggctcga ccatcggtgg gctgatcggg gcacggatcg ggcgccgtct taggccgatc
    12121 tggttacggg ccgccatagt ggtggtcggc acggtggcga tcgtgcagct gctcatccgg
    12181 tgattactcc attcggatgg gattcgttga ctggtgttca cctcgacgtg attgggtatc
    12241 ggaatgtctc cagccacccg cacagagcct gtacagctga ctgacggtcg tgcgctgcgc
    12301 atgacgtacg cggaaccaca cggggtcgtc agaggcggag tcgtcgtcct gcacgaggaa
    12361 cgcgggatga ccgaggcgat gcgggacctg atcaccgggc tcgccgccga gggctggctg
    12421 accgtcgcac cgcacatcta cgacggcgac tcgaccgaag tggacgacct cacggcgctg
    12481 gaccggatca gcgagctgtc cggtgagtcc gtgctcgccg acaccgacat cgcgttcggc
    12541 tggctcgcgc agcacggcat cgacgcggac cggatcggtg tggtcgggtt cgagctgggt
    12601 ggtgcggtgg cactggtggt ggccgcgagc cgggcgatcg gcgcggccgt gtccgtcggc
    12661 ggtggcggga tcctgaaccc gctctcgccc ggcctgcccg cactcgtgga cgcggcgccc
    12721 acgctgcgct gcccgtggct cggcctgtac ggggacaagg tcgccgacga ggtcgcgctg
    12781 ctgcgggacg cggcgaagcg ctcggagacg gccaacgacg tcgtgctgta cccggccgcc
    12841 gaccaccggt tcgacatcta cccggacacg gccgtcgaag cctggcagcg ggtcctgaac
    12901 tggttcgacg cgcacttgcg ctgaccggac cataattctc cgcgtgtccg cgacctcgtt
    12961 gtcccaccag gagttcgacc tcctgtggga gcacctcggc ttcaccgaac ggccctaccc
    13021 gctcgacgtg cgttccttcg ggtacaccat ggacgagcgg gcggcactgc gcgagcaggt
    13081 gcggcagtcc ttggcccaca agggactcca cgacggcgcc gaggtcgcgc ccgcgctgga
    13141 ggagcagctc gcgctgctcg gcaggcacac gcggagtgtc gacgggcggt tgtccgtcgg
    13201 cgagacactg cgggtgctcg cggcgagcga cggccgccgg ggcgtgctcg ccgcgcagtc
    13261 cgacgacgag gtccggctcg cgtgggtgcg gaacgcgcgg ctcgtgcccg cggtgatcgc
    13321 gttgctgccg gaccggcggc cagggccggg cgggtcggcg cggctgccca aggaggtctt
    13381 cgacgcggcc gtcgacgagt tcgccgcgag cgggtacgtc gggctggaac gcacgctcac
    13441 gaacggcggc gtgaccggcc gcgacctgcg cacggtcacc acgttgctgg agtccggcag
    13501 gcagggcggc gggcagctgg ccgcgaacag cgtcgaccag gtcggccgcc gcaccaggac
    13561 gtccgtgctg aactggttcg acaccgagcc cggccgctac ctcgtgcaca ccgaggtgac
    13621 cagggaccgg gtcgaatggc tgaccatcac ccccgccgac accgcgcgcg tcgagcagcg
    13681 cctgacggag atggcggcct cgctgaacca gccgtgagcg gccgcgcgac gcgttactgt
    13741 gacacctggt tctgatccgt caaagggggt tccccatgtc cgagcccagg gccttccccg
    13801 gcgcggcctc gggcgcgctc gcgccggtcg ccaccaaggt cggcaaggtc aaggagcagg
    13861 cgctcgccgg ctcgctgacg atcgacctcg aggtcgcgaa ggtcatcctc gtccagctcg
    13921 gcacgctgcg ggcccgcgcg gccgagctgg tccgggactg cgtggacctc gacacgccgc
    13981 tccggttcgg cgacaactgg gtcggccgga tcatgtccga gcggctgcgc atggtcgccg
    14041 tggacagcga cggcggcgtc acgcacgtgc tgaccgcgtt ccaccaggtc ctcgacgacc
    14101 tggaggcgac ggtccggttc gcggcgggca tgtacgagac gagcgacgag agtgcggcgg
    14161 acgacctgcg gcgcgcggtc gggcagttcg gcgtgacggt cgaggaggaa agttgagcga
    14221 gggcatcatg atcggtggct gttatccgcc gagctggccg cgcccgccga agccgccggt
    14281 ggacgagccg gtgccggagt cgctcgacga gaccgtcgag tggatgacct ggtcgcaccc
    14341 cgagctgtac cggatggtcc acgacggcat cgacctcacc ggcgcgatgt cggtgtccgc
    14401 gacgtgggcg cggctgggtg acgagctggc cgacatggcc gacgagctgt cgaagctgct
    14461 gttcacgacc tcgcaggcgt gggagggtga ggcggcggag ctcgcgaagg agagcgtgtc
    14521 ggcgctgtcg gagtggtcga gggagaccgc gatccgcgcg accgaggtgt gcgcctgcgt
    14581 caccgtccag gtcgacaacg tcgccaccgc gcgcaacgac atgccgcccc cgccgtaccc
    14641 ggtgctgccg acgccgacgc ccctgccctc gcaggtgacc gcgttcacca acggtggctt
    14701 cgacaccgcg acgccgctcg tggtggaccc gctggtctac acgacacagg aacgcgagct
    14761 gcacgagcag gccgcgcgga ccatggagcg gttccaggcg aactcgcggg acgtgtacgc
    14821 gaccgtgccc cagttcgcgc cgccgtcgct gcggaaggtg ccgtacggcc cgccgaccga
    14881 gccgccgcag ccacctccgc caccccagcc accgcagcca ccagtcccgc cgccagtgcc
    14941 gagggtgccc ggcggtggcc ccggccctgg cgcgggcggt ggtccggttt ccggtggtgg
    15001 tcctggcgcc gctggacccg gcacgccggg tcgtgccccg gccaccgccc cgctcgcccc
    15061 gggcggcggt gcgggaacgg gtgaaccagc ggcccggccc gctgccgcgt cggcggtgcc
    15121 ggtccggcag ggcggccagg cgccgggcat ggcaggcggt atgccgatgg gtggtggcgg
    15181 cgggagcggt cgcggcgagg acatcgagcg caggaacaag tacgtcgagg aggaccccga
    15241 catctggggc gccagcgacg agcgggtcat gccgccggtg atcggggagg tcaaccgccg
    15301 tgcgtgaccc tggctccggg tggatccagc tgagtgtggt cgagctgtac ctgctgtggt
    15361 cggcgatggg cctcggcccg acgcccgagg tgctggacgt gctgcacgta ggccgcacga
    15421 aggcgcggcg ggcggagctg gccgaggagt cgtcccgcga cctcgcggcc cgtgacctcg
    15481 gcacggtggc ggcaccggcc cgcgacctgg ccgggatgct gcggtcgctc ggcaacccgt
    15541 cggcgtcgct ggacatgcgg gtgtacggga cgggttcgcc gctgttcgcc ttcgccgcgg
    15601 tcggtccgtc cggcgccgcg atcgcggccc gcgtcggcga cgaggtccgg ttgggcgcgg
    15661 tccgcccgac ggcactcgcg tcgtcgctgc tcggctcgct cacccacctg cccgctgccg
    15721 ccgaccggcc ggccaacgtg agcgccgccg actacgacgc ggcgtgcgcg cagggtgccg
    15781 cggaaggcat ttccgggttc acgagggtgc tgcacgccgc gggtgtccgc gcggaggagg
    15841 tcagcacgct cacgcaggcg ctgacgtccc gcacgggcgg tggccagctc ggcgcgacgg
    15901 gccgggcccg cgcgtacagc ctggtcaact ggctggacac cccggacggc cggtacgccc
    15961 tgcgccgcaa cggctcgtgg atcaccctca ccccggccga cacggcccgc ctgaccacga
    16021 tggccgaaga gatgctcacc gacgtccgct gactgtgtcg cgcgtcacaa tttgctgatg
    16081 tcgaagatcc gggtgcggct ccgtcccagc ggcatgaacc gcgcgggaac gcgcacacct
    16141 gacgaggaga gtcaccatgg ccaagtacct gctgctcaag cactaccgag gcgcaccggc
    16201 cgccgtcaac gacgtgccga tggccgagtg gacgccggag gagatctcgg cccacgtgaa
    16261 gtacatggac gacttcgcgg cccggctcga ggagaccggc gagttcgtcg actcgcaggc
    16321 gctctcgccc gtgggcacgt tcgtccggta cgacggcgag gggcgcccgc cggtcaccga
    16381 cggcccgttc gccgagacca aggacctcat cgccggctgg atggtgatcg acgtcgacac
    16441 ctacgaccgc gccatcgagc tggcgggcga gctgtccgct gccccgggcg cgggcgggaa
    16501 gccgatccac gagtggctgg agctgcgccc gttctacggc tcggcgccga cgatcacgga
    16561 gtgagcatgg acgaggcgct gctcaggagc ctcaccccga acgtcctcgg catcctcgtc
    16621 cgccgcggcg ccgacttcgc ggcggccgag gacgccgtgc aggaggcgct gatcgaggcg
    16681 ctgcgcgtct ggcctgccga cccgccccgg gacccgaagg gctggctggt caccgtgtcc
    16741 tggcggaagt tcctcgacgc gaccagggcg gacgcggccc gtcgcaggcg ggaggacgcg
    16801 ggagaactcg tggccgaacc cgcgccggag ccggtgcccg cggtggacga cacgctccag
    16861 ctctacttcc tgtgcgcaca cccgtcgctg tcgccgtcgg ccgcggtcgc gctcacgttg
    16921 cgggccgtcg gcgggctgac cacccgccag atcgcgcagg cctacctggt gcccgaggcg
    16981 accatggggc agcgcatcag ccgggcgaag cggaccgtct ccggcgtgcg gttcgaccag
    17041 cccggcgacg tcgccaccgt gctgcgcgtc ctgtacctcg tcttcaacga gggctactcc
    17101 ggcgacgtcg acctggccgc cgaggccatc cggctcaccc gagggctcgc ggccgcgatc
    17161 gaccacccgg aggtggccgg gttgctcgcg ctcatgctgc tccaccacgc ccggcgggcc
    17221 ggccggacca cgccggacgg cggtctggtg ccgctcgccg agcaggaccg cggccggtgg
    17281 gacaccgcga tgatcgccga gggcgtcggg atcctgcagg cggcgctggc ccgcgaccgg
    17341 ctgggcgagt tccaggcgca ggccgccatc gcggccctgc acgcggacgc gcccaccgcc
    17401 gaggagaccg actgggtgca gatcgtcgag tggtacgacg agctggtgcg cctgaccgac
    17461 agcccggtcg tcctgctcaa ccgcgcggtg gcggtcggcg aggccgacgg gccgcgggcc
    17521 gggctggcgg cgctcgcggc gctggacgac tcgctgccgc gccacgccgc ggtggcggcg
    17581 tacctgcacg agcgcgacgg cgacctggcc gcggcggccc ggctgtacgt cgaggcggcc
    17641 agcaaggcac ccaacctggc cgaatgcgaa tacctgacgc gccaggcggc ccggctcaac
    17701 aaccgctgag ccctcagcgg ttggcgaggc cgtcgatccg cagggtcgcg gacggatccc
    17761 ggtgggtgcc ggtgccgccg acgtgcttgt cgctgatctc cgtgccgttc ttcagcacgt
    17821 ggcacagcgc catcccgtgg ccgcggccca ggtcgtagtc ggtcttgagc cattcgagga
    17881 cgacgcctgc cctggtggtc gcgtcgtagc cgcgcgcacc ggcctccgcc agcagctcgg
    17941 ccggggtctt gccggtcttc ttctcgatgc cgtctaggta ggcctggaag gacatgtcgt
    18001 ctccgtctgt cgtgggggcg gtgcccacgc agtctatgac aacttttcct gtccggacaa
    18061 cttttatttt cggaaggttc gtcggttctg ctcgcgggcg ctagtccggc aggagtcccg
    18121 cgtcgtggac cagtatcgcg atctggacgc ggttgttgag gtccagcttc gtcagggcgc
    18181 tcgacacgtg tgtcttcacc gtcggcacgg acaggtgcag cgccgtcccg atctcggcgt
    18241 tcgaccggcc cttgccgacc tccaccgcca ccgcgcgctc ccggtcgttg agcaccgcga
    18301 gacgggtcgc ggcacgggtc ccccgggtct ccgtctccgt cgcggcgacc ctcgcgacca
    18361 ggcgtttcat caccacgggc gacagcaccg gtgtgccttc cgcgacctgt cgcacggccg
    18421 ccacgatctg tgcgggcggc gtgtccttca gcaagaaccc ggccgccccc gctcgcagtg
    18481 cgcgcagcac gtgccggtcg gcgtcgaacg tggtcagcac cagtacctcg ggtgcgtccc
    18541 gccgcttgcg gagcgcctcc gtcgcggtga gaccgtcgac cgtcggcatg cggatgtcca
    18601 tcagcaccac gtgcgggcgg tgccggtcga ccagcgcgag cacctcggcg ccgtccccgg
    18661 cctcggcgac cacgcggatg tccggtgcgc cgccgagcat catggtcagc ccggtgcgca
    18721 cgagtgggtc gtcgtcgacg atcagcacgt ccacggtcat gccggccacg gtagccacgc
    18781 cgacacgcgc cagccgccgc cgggttccgg tccggcgtcg acccggccac cggccagtgc
    18841 cacgcgttcg cgcaaccccg cgagtccttg tccgccaccg ggttcgcccg gctcgcccgc
    18901 cgtgttgacg atctcgacgc ggagcccgtc cgcgtcccgc accgagatgt ccactgtgga
    18961 gcccgcggcg tgcttgcgtg cgttggtcag gctttcctgc acgatccggt acaccgtgcg
    19021 gccgagcgtg tccggcatct cggccgtgat ctcgttgcgc agcaccaccg gcatgccggc
    19081 gcgggcggac tcggcgacca gcgcgggcac gtccgcgaac gtcggctgcg gcagctcctg
    19141 cacgggcgcg cgcagcaccc cgatcacctc acgcaggtcc tgcagcgcct ggtgcgcgct
    19201 ctcgcggatc acccccgccg cccgcgcgat gtccgccgcc ggtgcgtccg gccggtactc
    19261 cagcgcgccc gcgtgcacgc tgagcagcga caaccggtgc ccgagcacgt cgtgcatctc
    19321 gcgggcgatc gcctcgcggg cctgcagctg cgcgcggtca gcccgcagcc gcgcctccgt
    19381 ctcggcgcgc gcggcccgtt cccgcagcga cagcaccagc tcgcgccggt gccgcacgac
    19441 cagcccccac ccgacgaccg cgcactgcac cgcgaacccg aacccgagcg agaacgcgag
    19501 cggctcgtcc ggcgcgggcc gcagcagcag gaacacgcac gtcgaggcca ggcccgcggc
    19561 gaacaggacg gcggtgaccc gcagcgaccg gtgcacggcc accgtgaaca gcgcgaccat
    19621 ggccgcgccc cccaccagtt ccgacacgca cgccacggcc atcagcgcgg ccgccacgcc
    19681 gaccggccac cgccgacgca gccacagcag cccggcgccg gcgaccccga ccagctggtc
    19741 gagcgcgaac agccactcct gccggggcgc cgagcccgtc tcgacgcgca tcgcgacgac
    19801 caggagcccg tacaacacgg cgaacatgaa cagcccgatg tccacagacc agtcgcgcag
    19861 gctgcgtctc atcgcccgaa cgtaccgagc ccgcgcgttc cggacgccga tcccagacca
    19921 aggtcgggaa aggtcggtac tttggtcggc cggtccgacc ggcgcgtgag tcaggcgccg
    19981 acgtactccg cgaggtgctc gccggtgagg gtggagtggt cggcgacgag ggcgctggga
    20041 gtgccctcga agacgaccag tccaccgtcg tggcccgcac cgggtccgag gtcgatgatc
    20101 cagtccgcgt gcgccatgac cgcctggtgg tgctcgatga cgatcaccga cttgcccgcg
    20161 tcgaccagcc ggtcgagcag gcccagcagg ttctccacgt ccgcgaggtg caggcccgtg
    20221 gtcggctcgt cgaggatgta gacgccgccg tcgccgccca tgtgggtggc gagcttgagc
    20281 cgctgccgct cgccgccgga cagcgtggtc agcggctggc cgatggtgag gtagccgagg
    20341 ccgacgtcgg ccaggcgatc gaggatcttg tgcgcggcag gcagcttggc ttcgccgtcg
    20401 ccgaagaact cctcggcctc ggtcaccgac atcgcgagca cctcgctgat gtcccggcca
    20461 ccgaacttgt agtccagcac ggacgcgtcg aagcgcctgc cctcgcacac gtcacacgtg
    20521 gtggacatgc cggccatgat cccgaggtcg gtgtagatga ccccggcgcc gttgcagccc
    20581 gggcacgcgc cctcggagtt cgcgctgaac agcgccggct tcacgccgtt ggccttggcg
    20641 aacgccttgc ggatcggctc cagcagaccg gtgtaggtcg cggggttgct gcgccgcgag
    20701 ccgcggatcg gggtctggtc gaccgccacc acaccgtccc gcttggcgac ggaaccgtgg
    20761 atcagcgagc tcttgcccga ccccgcgacg ccggtgacga ccaccagcac cccgagcggg
    20821 atgtcgacgt ccacgtcccg caggttgttc gtgtccgcgc cgcggatctc cagctgcccg
    20881 gacggctcac gcacgtcctc cttgagcgac acgcggtcgt c
//
