LOCUS       NZ_JACHJQ010000001     25035 bp    DNA     linear   CON 27-SEP-2024
DEFINITION  Actinophytocola algeriensis strain CECT 8960 Ga0436956_01, whole
            genome shotgun sequence.
ACCESSION   NZ_JACHJQ010000001
VERSION     NZ_JACHJQ010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinophytocola algeriensis
  ORGANISM  Actinophytocola algeriensis
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae.
REFERENCE   1  (bases 1 to 1326241)
  AUTHORS   Whitman,W.
  TITLE     Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the
            genomes of soil and plant-associated and newly described type
            strains
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1326241)
  AUTHORS   Whitman,W., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2020) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 154.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014203735.1-RS_2024_09_27
            Annotation Date                   :: 09/27/2024 05:42:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,095
            CDSs (total)                      :: 9,030
            Genes (coding)                    :: 8,881
            CDSs (with protein)               :: 8,881
            Genes (RNA)                       :: 65
            rRNAs                             :: 3, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2, 2 (5S, 16S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 44 of 149
            Pseudo Genes (incomplete)         :: 120 of 149
            Pseudo Genes (internal stop)      :: 3 of 149
            Pseudo Genes (multiple problems)  :: 17 of 149
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:06:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1069267
            Orig. end                         :: 1094302
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JACHJQ010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25035
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..25035
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25035
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15035](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15035)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            514..1539
                     /locus_tag="FHR82_RS05085"
                     /old_locus_tag="FHR82_001024"
     CDS             514..1539
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004558616.1"
                     /locus_tag="FHR82_RS05085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001024"
                     /product="6-phosphofructokinase"
                     /protein_id="WP_184809014.1"
                     /transl_table=11
                     /translation="MRVGLLTGGGDCPGLNAVIRAVVRKGIEAHGWETVGFRNGWLGPI
                     EGLTKPIGLDDVEDILTRGGTILGSSRTNPYKVDGGVDRIRETLAEHGVDALIAIGGED
                     TLGVAKRLTDDGIGVVGVPKTIDNDLGATDYTFGFDTAVHIATESIDRLRTTAESHHRA
                     LVVEVMGRHAGWIALHSGLAGGANVILVPERQFSVDQVVEWVERRFERQYAPIIVVAEG
                     ALPEGGQEKLLTGEKDAFGHVRLGGIGTWLAEEIAQRTGKESRAVVLGHTQRGGTPTAY
                     DRVLATRFGLHAVDAVQDGDFGVMVALRGTDIVRVKLSEATAELKTVPLERYQEAEVFF
                     G"
     gene            1565..2935
                     /locus_tag="FHR82_RS05090"
                     /old_locus_tag="FHR82_001025"
     CDS             1565..2935
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686272.1"
                     /locus_tag="FHR82_RS05090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001025"
                     /product="amidase family protein"
                     /protein_id="WP_184809015.1"
                     /transl_table=11
                     /translation="MDLDELLWSGADAQAAALRDGTVSAPDLLEAVLARLDAVNPALNA
                     FRVVYTEAARAQAADAQRRLDAGERTPLLGVPVAVKDDLDVAGDVTAMGGRPQFPPAEQ
                     DAPSVARLRAAGAVLVGHTNTPDRCLWPFTETLTNGATRNPWQLDHTPGGSSGGSAAAV
                     AAGVVGAATGSDGGGSVRIPANFCGLFGLKTTRDLIDMGDEEHWHGLAGVGPLGRRVAD
                     AAAMLDVIADEPGGYREAVDTDPGPLRIALSWRTPLGPAIIERQRKQAVLDTADRLRAL
                     GHAVTVTEPPLGVRPSPQFLVRYLRGVADDVAQLPHPEWLEPRTRRIAALGRRVPDSVL
                     ARSRAAEAGLHDLMAGFFGQFDVILQPGWTGRQPRIGRFHGSGASHTLAAVSQGIAFFP
                     TWNVLGYPVAALPVGFDDIGLPIGVQLIGAAGSEATLLSLSGQFERAHPWTSRRPSL"
     gene            3111..4499
                     /locus_tag="FHR82_RS05095"
                     /old_locus_tag="FHR82_001026"
     CDS             3111..4499
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800237.1"
                     /locus_tag="FHR82_RS05095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001026"
                     /product="class II 3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="WP_184809016.1"
                     /transl_table=11
                     /translation="MNWTVDVPVDTLPELPPLPPALRARLDDALSRPAAQQPDWPDREQ
                     LHQVRTLLESVPPITVPNEIDRLRDKLAEVARGEAFLLQGGDCAETFVDNTEPHIRGNI
                     RTLLQMAVVLTYGASLPVVKVGRIAGQYAKPRSNTTDALGLPVYRGDIINSLVPKHEAR
                     VPDPGRMIRAYANAGAAMNLVRALTAAGMADLSKVHEWNKDFVSNSAAGERYEALATEI
                     DRGLRFMQACGVEDTSLHSTEIFASHEALLLDYERALLRMDTRGPDPRLYNLSSHFLWI
                     GERTRQLDGAHIAFAELLSNPIGVKIGPTTTPELAVEYVERLDPHNTPGRLTLISRMGN
                     GKVRDALPPIVEKVEASGHRVIWQCDPMHGNTHESSTGYKTRHFDRIVDEVQGFFEVHR
                     RLGSHPGGIHVELTGEDVTECLGGAQDISDDDLAGRYETACDPRLNTQQSLELAFLVAE
                     MLRS"
     gene            complement(4588..5805)
                     /locus_tag="FHR82_RS05100"
                     /old_locus_tag="FHR82_001027"
     CDS             complement(4588..5805)
                     /GO_function="GO:0004144 - diacylglycerol O-acyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0045017 - glycerolipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020671591.1"
                     /locus_tag="FHR82_RS05100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001027"
                     /product="wax ester/triacylglycerol synthase
                     domain-containing protein"
                     /protein_id="WP_184809017.1"
                     /transl_table=11
                     /translation="MGRLTGLDAAFLSLETRERPMHLGAVAVFRGPVPAGRLRTLLVER
                     AARLPGLRVDGGWFPSWWPASDFDPAGHVHTYEVAGQRTFEAYAAGWLATPLDLSRPPW
                     DVHVVTGLSDDRFAVLVKLHHALADGAGAVALAGALLDGGLPHSRATDPPSYGIGQTAA
                     MAGAVARAVRVPPVPAMRTSGGTARRVSFVRLDLADVRQIRRRHGGTTNDVALAVLTGG
                     LREWLRSRGAPVDGRAPRALIPVNTRARGGAGGNQLSGYLCDLPVGLTDPVARLRAVRS
                     AMDANKAAGPSRGAGTLPILANLLPPAVHRLCGPITGLGAPLLFDTVVTTVPLPSVPLT
                     VAGAPLAEIYPFGPLAPGHAVGVAISPYRDAVHIGLQADRDAVPDLDVLSHAIAKACTT
                     LHELAQ"
     gene            complement(5883..8018)
                     /locus_tag="FHR82_RS05105"
                     /old_locus_tag="FHR82_001028"
     CDS             complement(5883..8018)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020671593.1"
                     /locus_tag="FHR82_RS05105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001028"
                     /product="PASTA domain-containing protein"
                     /protein_id="WP_311770877.1"
                     /sec_met_domain="Pkinase (E-value: 1.2e-45, bitscore:
                     152.2, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDERGVGLIGALLEQRYRVDALLARGGMSSVYRGLDTRLDRRVAI
                     KVMDARFADDRAFVDRFEREARSAAKIHHPNVVAVHDQGVDKSPNGDLVYLVMELVDGG
                     TLRDLINERGALDVPTALAIMEPVLSALAAAHRAGLVHRDVKPENVLIGHGGEGGSTVK
                     VGDFGLVRAIHSAGTTSASVILGTVAYLSPEQVTTGNANSAGDVYSAGIVLFEALTGTA
                     PYTGDNAISVAYRHVNDDVPAPSTLAGNIPPELDDLVVRATRRDMEQRPVDGAAFLSEI
                     EKLRMVIGAPRVPVPVPAPTIADRTMPVSPETIRHSSGVIDTSEAERTVRNAPVVSPAV
                     APVAPAGATIVRQAPPGGFRPIGPQGTRAMLRTDLDRAGPATEYVPPVSGPFPSQQPQA
                     APPRPPRNRPPQPPPARKGRGGSIALWSAVAVLVLALVGTSTWWFASGRYRTVPDVAAM
                     ARDDAERKLRDNDLDPQIKTERHNTIAAGTVIRTDPAQGQEVLRGDSVTMVVSLGKPKV
                     PEVREGADPTEVEDLIRKQGLQPDRDDGQNRYDDDVEKGKVVSVSPQPGTELNIGERVV
                     IVLSKGPEPKPIPDVRNKTRDEAFQELTALGYTPVEGTAEFSADVEGGRVIRTDPEIGS
                     KIEGDDKTVTVIVSNAVTVPDLGNQSADQAVATLQQLGLQAEIQAFGGGSGRVIGQSPT
                     ANSKVAPNSKVVIWVIP"
     misc_feature    8108..8123
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            8178..8549
                     /locus_tag="FHR82_RS05110"
                     /old_locus_tag="FHR82_001029"
     CDS             8178..8549
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657740.1"
                     /locus_tag="FHR82_RS05110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001029"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_311770878.1"
                     /transl_table=11
                     /translation="MSAIPSADDVLGPDVEVLPLPDVADRLALPVTKVRQALRDGQLLA
                     VRRNGVLSVPTPFLTADGQIVKGLPGTITVLADAGFTPDDMLRWLFEPDETLPGGTPIA
                     ALRATGGREVKRRAQALAF"
     gene            complement(8531..9232)
                     /locus_tag="FHR82_RS05115"
                     /old_locus_tag="FHR82_001030"
     CDS             complement(8531..9232)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0030416 - methylamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018942.5"
                     /locus_tag="FHR82_RS05115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001030"
                     /product="MauE/DoxX family redox-associated membrane
                     protein"
                     /protein_id="WP_184809019.1"
                     /transl_table=11
                     /translation="MAALSQGFALALAGLLVSAGAPKLWRPGHVAGALRRVFGPRGSTS
                     ALRRHGRLLGAWELLLAAAVVHVGGRVTGVALAVTFAGFLGFVVVAVRRGSSCGCWASL
                     TEGPAGGAELARTAVLAAAAGYVAGTGWPRGVSVAALGWAGALLAVMVLAAVAGGRIAP
                     VRSAGVARRLARRAAPTRRGRLLARLAFLAGFVHIGTDAEQARLRRALDATQRTATQRT
                     VTRAAGQKARA"
     gene            complement(9232..9510)
                     /locus_tag="FHR82_RS05120"
                     /old_locus_tag="FHR82_001031"
     CDS             complement(9232..9510)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FHR82_RS05120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FHR82_001031"
                     /product="hypothetical protein"
                     /protein_id="WP_184809020.1"
                     /transl_table=11
                     /translation="MSWDDFTACAGRDGEILVEIGEDGVKEIAGLWKMLPQDVKAMLIA
                     AARWGGVYLEAALAAVGIAAAEAIAAVAAGAGLGVIMAVIMDCYDHL"
     gene            complement(9526..9924)
                     /locus_tag="FHR82_RS05125"
                     /old_locus_tag="FHR82_001032"
     CDS             complement(9526..9924)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FHR82_RS05125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FHR82_001032"
                     /product="hypothetical protein"
                     /protein_id="WP_184809021.1"
                     /transl_table=11
                     /translation="MTVPEGAQLSDDGNYWWDGTDWQPTGNAATGDVGGGIADALAQQG
                     IAIAPEAADAGYIQQIALHVNSWYEGLDENSRAIVDALSRQGADLLLADPEVGVVSEGD
                     PLITAFSANGMTLHESLSATNQALEQTA"
     gene            complement(10001..10933)
                     /locus_tag="FHR82_RS05130"
                     /old_locus_tag="FHR82_001033"
     CDS             complement(10001..10933)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005437541.1"
                     /locus_tag="FHR82_RS05130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001033"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_311770879.1"
                     /sec_met_domain="phytoene_synt (E-value: 9.1e-110,
                     bitscore: 362.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 7.1e-67,
                     bitscore: 222.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGLFGAAGRKSTPALDEAYRACRRINARYGRTYFLATRFLPAAS
                     RPSVHALYGFARLADEIVDNAVAPGDPAQALTTLEKALAEAFAGAPPAHPVLLALTDTV
                     RRHDIDEALFTEFLASMRMDLTITGYATFADLAEYTHGSAGVIGLQMLPVLGTEGPREE
                     AAPYAAALGEAFQLTNFLRDVGEDLDRGRLYLPADELAAFGVDRAMLEHAHRTGRTERP
                     IRRALAHLVSCTHAVYRRAEPGIALLAPRSRPCIAAATAMYRHILDEIADAGYDVLGRR
                     VVVPTHRRLRIAVSAMARALPFRVAPRSR"
     gene            complement(10930..12324)
                     /locus_tag="FHR82_RS05135"
                     /old_locus_tag="FHR82_001034"
     CDS             complement(10930..12324)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FHR82_RS05135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FHR82_001034"
                     /product="hypothetical protein"
                     /protein_id="WP_184809022.1"
                     /transl_table=11
                     /translation="MTRKPRRLVPFLVVAVLGLTACTNAVGGAPSGVEIGPLTTAEATA
                     SALTSFAESAATRYQGGLKASDGSAFTVDVTATSTSEVFGTITVDGLGATITVLDKTLY
                     LKGAPEFWAAMAARFGVSSGDGTALGNRWVKLPTVLLGIEFADIFTPDVVSQAAGKATK
                     GDGALPDKTTKVAEVEGLEVPVDGGKVYLAKDAPHGVVAIALDEIGSAENTKARDLQVA
                     VSDVSANINKIYTDLANGATKDLGTAIDALTTITQGGNRFDACGAPSCTLIVDITNPSK
                     KAVKVHLKADWTGDNAPLGSCEQTVGPVQPGAAATMSCAITTPEWGSFYQRANSVPGSH
                     PYGAVWTALALADPPDAKPLEERATAKPADTKSGREGESGHAVYAISYADSVWKYGVAS
                     ARYWRDQAKEQLRGCLGTTKSVCTASLVTTAENPVSAYALATQLVATYKQENGECPAGQ
                     WVSCPK"
     gene            complement(12390..13910)
                     /gene="crtI"
                     /locus_tag="FHR82_RS05140"
                     /old_locus_tag="FHR82_001035"
     CDS             complement(12390..13910)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020671598.1"
                     /locus_tag="FHR82_RS05140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001035"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_184809023.1"
                     /sec_met_domain="DAO (E-value: 1.4e-13, bitscore: 47.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALPGATDRVVVVGAGLAGLSAALHLIGAGREVTVLESAPHVGG
                     RAGADRLGAYRIDTGASVLTMPDLLDEAFSAVGSSLAERVELTRLDPAYRAHFADGSTI
                     HVHTGADAMAEEVRRVAGPREAAGYLRLRQWLTSLYRVQREEFIGANFDSPLDLLGPKL
                     AHLAAMGGFGRLGPRIGRYLSDERLRRLFSFQSLYAGLAPAEALAAYGVIAYMDTVAGV
                     WFPRGGVGAVAEAMAAAAADAGGSVRTGTGAAWLERTGDRVTAVRTTHGERIPCDAIVL
                     TPDLPVSYRLLGRTPRRPLRPRWSPSAVVLHVGVTRTWPELGHHTVFFGTHWDRTFDEI
                     LHRGKLMSDPSLLVTRPTATDQALAPSGREVISVLAPCPNQETGEIDWDRVGPAYRAEL
                     GQVLAARGLTGFDDAVEVERLVTPADWAAAGLAAGTPFSLAHTLQQTGPFRPRNLVGGV
                     ANAVLAGCGTTPGVGIPPVVISGRLAAQRVTGAQRQRSVSSSPRVAAR"
     gene            complement(13911..15035)
                     /locus_tag="FHR82_RS05145"
                     /old_locus_tag="FHR82_001036"
     CDS             complement(13911..15035)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011208270.1"
                     /locus_tag="FHR82_RS05145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001036"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_376706385.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.6e-49, bitscore:
                     164.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVTPERVAADMAEDIDMAVHRHVEKLLRGYLAERRAELPALAQ
                     TFAAAVDTLSDFALRGGKRIRPTFAWWGWRAAGGEGTGTRAEAVLTAVSALELIQTCAL
                     VHDDLMDASELRRGHPTVHVRFTDAHRAGGWLGEPERFGMAAAILLGDLALAWADDMFT
                     GAPLSDRMRGAARGPWLAMRAEMFAGQYLDVLAQAEGDESEERALGVARLKTAAYTVER
                     PLHMGVALAGADEDTIAAVRAFGTDVGVAFQLRDDLLGVYGDTEVTGKPAGDDLREGKR
                     TLLVSLGLGYADEAGRHADADLLRRALGDPGLTQETIQRVRDLLVEVGAVDELERRIEK
                     LTVSAMAALDAAGLDEPGRTRLADLAIAATRRDR"
     gene            15116..16021
                     /locus_tag="FHR82_RS05150"
                     /old_locus_tag="FHR82_001037"
     CDS             15116..16021
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005465634.1"
                     /locus_tag="FHR82_RS05150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001037"
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="WP_184809024.1"
                     /transl_table=11
                     /translation="MTSVVARIPGDRPVFSVEFMPPRDDADELRLWNAIRSLEGLDPAF
                     VSVTYGAGGSSRDRTIRTTGRVVTETTLVSMAHLTAVDHSVAELRNVIGWYASLGIRNV
                     LALRGDPPGDPNGEWVKHPEGLEYAEELVSLVRSLGDFCVGVSAFPYGHPRSADLDEDT
                     RYLVSKLRAGADFAIAQLFFEADDFLRLRDRVAAAGCETLLLPGVMPLTTPRILSKTVE
                     LSGADVPASLAGRLDPLAGDAKAFREEGMNVTTELCERLLAEGVPSLHFYTFNRSKATK
                     EIVVDRLGLAPGRSQLRSVG"
     gene            complement(16130..16807)
                     /locus_tag="FHR82_RS05155"
                     /old_locus_tag="FHR82_001038"
     CDS             complement(16130..16807)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF047061.1"
                     /locus_tag="FHR82_RS05155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001038"
                     /product="LppM family (lipo)protein"
                     /protein_id="WP_184809025.1"
                     /transl_table=11
                     /translation="MRRVSRVTGLFALFAVLMLSLTGCLRIHTALAVSPEDTVSGELII
                     AALPVSEQDNGPPLTIPPELNDRVRAEKYTQDGYVGQKVTFKELRFTDVATLVESISEA
                     NQYRLSLRRVGGRVTLAGSVDLTQVPKDRADIQIKIAFPGPVTRTDGDEDDSTISWSPK
                     PGAVTEFNAIAEYSNGGGESLMKWVTIVGGGALLAAVIAALLALIAHRRSLSADRAQAV
                     GRY"
     misc_feature    complement(16664..16666)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16884..18539
                     /locus_tag="FHR82_RS05160"
                     /old_locus_tag="FHR82_001039"
     CDS             16884..18539
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020419643.1"
                     /locus_tag="FHR82_RS05160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001039"
                     /product="DUF885 domain-containing protein"
                     /protein_id="WP_225943944.1"
                     /transl_table=11
                     /translation="MTVHRISDDYVDDYVRLVPTIATELGIPGYDDQWPDLSPEGNAAV
                     AGLARRALADVSAVEPSDDAERVAKAVFTERLGVEVELYDAGLIDSDLNVLASPPQSLR
                     STFDLMPTSTADDWSTIATRLSRLPAALAGYRVSLLHAAAKGNVSAVRQVTKVADQCQK
                     WSQGFFTDFVAGAKDVPDTVRTDLDAGAAAASKAYGELAEFLRAEVLPKAPGKDAVGAE
                     AYKLLSRRYLGAALDLREAYEWGWTEFLRLEAEMKEVANRVKPGASLAEAAAALDNDPR
                     YQVRGVEAFREWMQKLSDQALSDLRGVHFDIPDEIMRLDCKIAPPGGTAGAYYTNPTDD
                     FSRPGAMWWALPPDKDEFTTWREASIVYHEGVPGHHMQIATAMYHAERLNKFQRMLSWV
                     PAYSEGWALYAERLMREFGYLSDDGNLFGMLNENIFRAARVIIDIGMHLELEIPAGTGF
                     HEGARWTPDLGLEFMLTRTITEHELVVDEVDRYLGWAGQAPAYKLGERLWLEARDDAKA
                     RAGGAFDLKHFHMESLYLGQMGMDTMRECLSRIQ"
     gene            complement(18598..18759)
                     /locus_tag="FHR82_RS47245"
                     /old_locus_tag="FHR82_001040"
     CDS             complement(18598..18759)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FHR82_RS47245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FHR82_001040"
                     /product="hypothetical protein"
                     /protein_id="WP_311770880.1"
                     /transl_table=11
                     /translation="MTEVDRPLRVGNQARLRELVREHGDEVRVFSAHDPWAFAEVAGLA
                     RGGVPSMP"
     misc_feature    complement(18818..18827)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.55"
                     /tool="antismash"
     gene            complement(18854..19435)
                     /locus_tag="FHR82_RS05165"
                     /old_locus_tag="FHR82_001041"
     CDS             complement(18854..19435)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012955.5"
                     /locus_tag="FHR82_RS05165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001041"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_311770881.1"
                     /transl_table=11
                     /translation="MNVTHLNCGTMREIPADGREPARVVCHCLVIEAEHGLVLVETGFG
                     AVDVTQPSVALGDAFLERTAPVLSPSETAAAQLIARGYAPSDVTDIVLTHLDLDHSGGL
                     PDFPGARVHLHDAEYRAAMAVSDAHPEHTLRYPARALGSSAALGDLSVTAGRVVVRVRR
                     RAAGRTAIGVVAGAPRRALRRALRGGGPNR"
     misc_feature    complement(19471..19486)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(19482..19497)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     misc_feature    19490..19505
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.13"
                     /tool="antismash"
     misc_feature    complement(19493..19508)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.85"
                     /tool="antismash"
     misc_feature    complement(19605..19621)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.02"
                     /tool="antismash"
     gene            19733..21196
                     /locus_tag="FHR82_RS05170"
                     /old_locus_tag="FHR82_001042"
     CDS             19733..21196
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020643814.1"
                     /locus_tag="FHR82_RS05170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001042"
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="WP_184809027.1"
                     /transl_table=11
                     /translation="MATDAEVIGVRGVFLKLRTHAGLTARRLRDTEVDTRVLADLPAVQ
                     RAIRESGAPVEQAIVDAVAAVVAELDPTDRLIADVVLALGMLADRLTDQPALANRLYRA
                     DLGVRRVALSEGWATLHELMGVEHPPQAPTVRSLRGSVEEKTLGVLAERCVRAAGMARR
                     ESTEEPGNAVVVVGGAVMDHITVVESLPVAGESVQATSFHMNPGGKGLNLAVAGRRMGF
                     DVRFAAAVGDDAAATRLLEYMSEQNLGTDLIVEAPGEATPVAQVIVLPNGDAATIGWKN
                     ELRVALSTRDMRSQAMSRALAEADAVLVTLEAPVDVVKWTLDTARTLPRKPLVLLQASP
                     PLDRPQQIYRQLTGVDYVVGSEWALSKLLPPFNDDKSIDEIARQLRTMGVATVCVVENF
                     RCRIRSRELEADFDAPSVPLTDSPGAREAFSAALIHHLLRIGRGGLTRESLEWASAAMA
                     TNLSIDIITDAMPKPGDVGRIMESDQSVG"
     misc_feature    19773..19787
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.32"
                     /tool="antismash"
     gene            21202..21981
                     /locus_tag="FHR82_RS05175"
                     /old_locus_tag="FHR82_001043"
     CDS             21202..21981
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF001591.0"
                     /locus_tag="FHR82_RS05175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001043"
                     /product="GTP cyclohydrolase II"
                     /protein_id="WP_311770882.1"
                     /transl_table=11
                     /translation="MGDVNLTEHELRHADGDFRVVVLGRGSDMHGNQPCAAVFGEPGNG
                     CLVRIHSRCVYGEIFESVDCDCRDQLRQSMAMMRKVGSGVLIYLDQEGRGAGLLAKALG
                     YQLTQREGLDTFSSYRVLGLPEDSRSYEDAVAILRNLGLRRVRLLTNNPAKVAALSTAD
                     FQVEQQPFLVRGQSAEARRYLAAKARFGHTISIAELEADAARDRWRWLHKLLRRTWRKP
                     AQETPERAPARVVELPVPTVNPVEQSVTSAQPTDLVS"
     gene            complement(22057..22635)
                     /locus_tag="FHR82_RS05180"
                     /old_locus_tag="FHR82_001044"
     CDS             complement(22057..22635)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064527.1"
                     /locus_tag="FHR82_RS05180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001044"
                     /product="N-acetyltransferase"
                     /protein_id="WP_184809028.1"
                     /transl_table=11
                     /translation="MTAVPPRVERFVDLSPDELRACLPEALSLYVTAMRYPSGTAEQRA
                     PMWLAHMLRAEWRCVGAFNADHRMVGVAYGYRGAAGQWWHEQVRRGIIEQSGAELADRW
                     LEDYFELTEVHVSPASQGRGIGEELLRRLLGGVRASKVLLSTPEGPTRAWRLYYRLGFT
                     DVLRHYRFTGDPRPFGVLGRVLPVPPPRN"
     gene            complement(22653..23153)
                     /locus_tag="FHR82_RS05185"
                     /old_locus_tag="FHR82_001045"
     CDS             complement(22653..23153)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156538.1"
                     /locus_tag="FHR82_RS05185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001045"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_184809029.1"
                     /transl_table=11
                     /translation="MTSLDHPSISKLAAALLEAGLSPAADGIRLLDDEVRTAAAAAQAL
                     GVEVGAIANSLVFRATYGDEVRPLLALTSGAHRADTATLAALVGADEVGKADPAFVREH
                     TGQAIGGVAPVGHPHPVRTVVDADLARYEVVWAAAGHPKSVFPTTYADLVALTGGTAAD
                     VAG"
     misc_feature    complement(23246..23261)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 26.01"
                     /tool="antismash"
     misc_feature    23247..23260
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.39"
                     /tool="antismash"
     gene            23373..23786
                     /locus_tag="FHR82_RS05190"
                     /old_locus_tag="FHR82_001046"
     CDS             23373..23786
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686257.1"
                     /locus_tag="FHR82_RS05190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001046"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_184809030.1"
                     /transl_table=11
                     /translation="MTATLDFPNHHSATPESALGLLAQAETGLSTAELEEDAARRFADA
                     YLAALRAAAALLAMRGRPHRARSRPMSVWTLLSSVAPELREWAAFFASCSATRASVQAG
                     ITRAVSTRSADDLVRQSGQFIELVSRLIRGADR"
     gene            23783..24544
                     /locus_tag="FHR82_RS05195"
                     /old_locus_tag="FHR82_001047"
     CDS             23783..24544
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686256.1"
                     /locus_tag="FHR82_RS05195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHR82_001047"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_184809031.1"
                     /transl_table=11
                     /translation="MTVTPLVDFARLLDVLDTEGERLATSATGTDPELEVPHLPGMRLG
                     EVVRHVGSVYRMVVSWLRDGERPTRWQREPAPDQSVVDYFRAGLLEVVDELDRHDPLEG
                     APTWWPEHQNFGFWCRRLAHETTVHRVDVQLTGAKLLVGDIAAEVALDGIDELMSLWFT
                     HRLGVLGVSDVVPGRVAVNAGGRRWIARVSTTGASAWRTDEDEPAEATVSSDATGMYLW
                     LWGRRPGAYVQESGDPALVAQLRSLLRVATR"
ORIGIN
        1 tcgaccgagt tcgacccggg cagggcgggc ccatgggtgc gggacaacgt gctcgacaag
       61 ctgccgtcgc ccgccgaccc ggcgtggtgc gaccgcgcca cgatccgcga tcgcctcatg
      121 aagttcctga gccgcgatcg cgagcgggtc gagctgtggg cctggttcgc cgcgtacgac
      181 cacgtcgcgc tcgcgcagct gtggggtgac atgcccgcgc tgccgaggga actgccccgg
      241 ttcacccgcg agctgcgcca gcggtgggag gacgtgggca aaccgtcgct gccgcccccg
      301 cccagcgacg cgcacgacgc gctcgccgat gcccgccaca acctcgtccg ctggaaggtg
      361 atcgaggcgg aacgtgtcag gagagggttc cccgtcagtt gaccggggca ccttgctgca
      421 ccgatccaga gaatggcact ctacgggctg acaaacgcac tcaggacccg aacaggaccc
      481 cgtgctcctg cggccggatg gaggatcgag cacatgcgcg tcggtttgct cacaggtggc
      541 ggtgactgcc caggactcaa cgcggtcatc cgcgctgtgg tccgcaaggg catcgaggcc
      601 catggttggg agacggtcgg gttccgcaac ggctggctcg gcccgatcga ggggctgacc
      661 aagcccatcg ggctcgacga cgtcgaggac atcctgacca ggggtggcac gatcctcggt
      721 tcgtcgcgga ccaacccgta caaggtcgac ggcggcgtcg acaggatcag ggagacgctc
      781 gccgagcacg gtgtggacgc cctgatcgcg atcggcggcg aggacaccct cggggtggcg
      841 aagcgcctga ccgacgacgg catcggcgtg gtcggcgtgc cgaagacgat cgacaacgac
      901 ctcggcgcga ccgactacac gttcggcttc gacaccgcgg tgcacatcgc gaccgagtcg
      961 atcgaccggc tgcgcacgac cgccgagtcg caccaccgcg cgctggttgt cgaggtcatg
     1021 ggccgccacg ccggttggat cgcgctgcac tccggtctcg cgggcggcgc gaacgtgatc
     1081 ctggtgccgg agcgccagtt ctccgtcgac caggtcgtcg agtgggtcga gcgccggttc
     1141 gaacgccagt acgcgccgat catcgtggtc gccgagggcg cgctgcccga gggcggccag
     1201 gagaagctgc tgaccggtga gaaggacgcg ttcggtcacg tgcgccttgg tggcatcggc
     1261 acctggctcg ccgaggagat cgcacagcgg accggcaagg agtcccgtgc ggtcgtgctg
     1321 ggccacaccc agcgcggcgg caccccgacc gcgtacgacc gcgtgctcgc gacccgcttc
     1381 ggcctgcacg ccgtggacgc ggtgcaggac ggcgacttcg gtgtgatggt cgcgctgcgc
     1441 ggcaccgaca tcgtgcgcgt gaagctgtcc gaggccaccg ccgagctgaa gaccgtgccg
     1501 ctggagcggt accaggaggc cgaagtcttc ttcggctgag cccgtgcggg gctaatgttc
     1561 ccgcatggac cttgacgagc tgctctggtc gggcgcggac gcccaggccg ccgccctgcg
     1621 cgacggcacg gtgtccgcgc ccgacctgct cgaggcggtg ctcgcccgcc tcgacgcggt
     1681 caacccggcg ctgaacgcgt tccgcgtggt gtacaccgag gcggcgcgtg cgcaggcggc
     1741 cgacgcgcag cgacggctcg acgctgggga gcgcacgccg ctgctggggg tcccggtcgc
     1801 ggtgaaggac gacctggacg tggccggtga cgtgaccgcc atgggcgggc gcccgcagtt
     1861 cccgcccgcc gagcaggacg cgccctcggt ggcgcgactg cgggcggcgg gtgcggtgct
     1921 ggtggggcac acgaacacgc cggaccggtg cctgtggccg ttcaccgaga cgctcaccaa
     1981 cggcgccacg cgcaacccgt ggcagctcga ccacacacca ggcggctcgt ccggtggttc
     2041 cgccgcggcg gtggccgcgg gcgtcgtcgg cgcggcgacc ggctcggacg gcggcggctc
     2101 ggtccgcatc ccggcgaact tctgcggcct gttcgggctg aagaccaccc gcgacctgat
     2161 cgacatgggt gacgaggagc actggcacgg cctcgcgggc gtcggcccgc tcggccgccg
     2221 cgtggccgac gcggccgcga tgctggacgt gatcgccgac gagccgggcg gctaccgcga
     2281 ggccgtcgac accgatcccg gcccgttgcg gatcgcgctg tcgtggcgca ccccgctcgg
     2341 cccggcgatc atcgagcggc agcgcaagca ggcggtgctc gacaccgccg accggctgcg
     2401 cgcgctcggg cacgcggtga cggtgacgga gccgccgctc ggggtgcggc ccagcccgca
     2461 gttcctcgtg cggtacctgc gcggggtggc cgacgacgtc gcgcagctgc cgcacccgga
     2521 gtggctggaa ccgcgcacgc gccgcatcgc cgcgctgggc cgccgggtgc cggactcggt
     2581 gctggcgcgc tcccgtgccg cggaggcggg gctccacgac ctgatggctg ggttcttcgg
     2641 ccagttcgac gtgatcctgc agccggggtg gaccgggcgg cagccacgta tcggccggtt
     2701 ccacggcagc ggcgcgtcgc acacgctggc cgcggtgtcg cagggcatcg cgttcttccc
     2761 aacgtggaac gtactcggct acccggtggc ggcgctgccg gtcggcttcg acgacatcgg
     2821 cctgccgatc ggggtgcagc tgatcggcgc ggccggctcg gaggcgacgc tgctgtcgct
     2881 gtcgggccag ttcgagcggg cgcacccgtg gacgtcgagg aggccgtcgc tgtaggcgtc
     2941 gccgtgcacc tggcgcccgc tccctccgct gggacggtgg cgtgctcctg tcccagatcg
     3001 cgggaagcac gtggccaggg gatggccgat cgtccacgta ctggtgaaac gatcaagccg
     3061 cgggtgctgt cgccgtaaac cgggctgaca cgccgggcta ccctggtgcc gtgaactgga
     3121 ccgttgacgt gccggtggac acgcttcccg agctcccgcc gctgccgccg gcactgcgcg
     3181 cccgcctcga cgacgcgctg tcccggcctg ccgcgcagca acccgactgg ccggaccgcg
     3241 agcagctgca ccaggtgcgc acgctgctgg agagcgtccc gcccatcacc gtccccaacg
     3301 agatcgaccg cctgcgcgac aagctcgccg aggtcgcccg cggcgaggcc ttcctgctgc
     3361 agggtggcga ctgcgccgag accttcgtgg acaacaccga gccgcacatc cgcggcaaca
     3421 tccgcacgtt gctgcagatg gccgtcgtcc tgacctacgg cgcgagcctg ccggtcgtga
     3481 aggtcggccg catcgcgggc cagtacgcca agccgcgctc gaacaccacc gacgcgctcg
     3541 gcctcccggt gtaccgcggc gacatcatca actcgctcgt gcccaagcac gaggcacgcg
     3601 tgcccgaccc gggccgcatg atccgcgcgt acgccaacgc gggcgcggcc atgaacctcg
     3661 tgcgcgccct caccgcggcg ggcatggcgg acctgtcgaa ggtccacgag tggaacaagg
     3721 acttcgtcag caactcggcg gccggtgagc ggtacgaggc gctggccacg gagatcgacc
     3781 gcggcctgcg gttcatgcag gcgtgcgggg tcgaggacac gtcgctgcac agcacggaga
     3841 tcttcgcgag ccacgaggcg ctgctgctcg actacgagcg cgcgctcctg cgcatggaca
     3901 cccgcggtcc cgacccccgg ctgtacaacc tgtcgtcgca cttcctgtgg atcggggagc
     3961 ggacccgcca gctcgacggc gcgcacatcg cgttcgcgga gctgctgtcc aacccgatcg
     4021 gcgtcaagat cggcccgacc accacgccgg agctcgcggt cgagtacgtc gagcgcctcg
     4081 acccgcacaa caccccgggc cgcctgacgc tcatctcccg catgggcaac ggaaaggtgc
     4141 gcgacgcgct cccgccgatc gtggagaagg tggaggcgtc cggccaccgg gtgatctggc
     4201 agtgcgaccc gatgcacggc aacacgcacg agtcgtccac cggctacaag acccgccact
     4261 tcgaccgcat cgtcgacgag gtccagggct tcttcgaggt gcaccggcgc ctcggctccc
     4321 acccgggcgg catccacgtg gaactgacgg gcgaggacgt caccgagtgc ctcggcggcg
     4381 cccaggacat ttcggacgac gacctggcgg gccgttacga gaccgcgtgc gacccgcgcc
     4441 tgaacaccca gcagtcactg gagctggcgt tcctggtcgc ggagatgctc cgcagctgac
     4501 ccggccccgc acggcgcccg cggaatgcca tgaaaacgct ttcggggacg ctcaacgtcc
     4561 cgaaagcgtt ttaaggcacc gggcaactca ctgcgccagt tcgtgcaacg tcgtgcacgc
     4621 cttggcgatc gcgtgcgaga gcacgtcgag gtccggcacc gcgtcccggt cagcctgcag
     4681 tccgatgtgg acagcgtccc ggtagggcga gatcgcgacg cccacggcat gtccgggtgc
     4741 caacggccca aagggataga tctccgccag cggcgcgccg gccacggtca acggcaccga
     4801 cggcagcggc acggtggtca ccacggtgtc gaacaacagc ggcgccccga gcccggtgat
     4861 cggcccgcac aaccggtgca cggccggagg aagaagattc gcgaggatcg gcaacgtgcc
     4921 cgcgccgcgc gaaggccctg ccgccttgtt cgcgtccatc gccgagcgga cagcgcgcag
     4981 ccgcgccacc ggatcggtga gaccgaccgg caggtcgcac aggtaccccg acagctggtt
     5041 gccgcctgcg ccgccacggg ctcgcgtgtt caccgggatc agcgcacgcg gagcccggcc
     5101 gtccaccggc gcgccccgcg accgcagcca ctcccgcagc ccgccggtga gcacggcgag
     5161 cgccacgtcg ttcgtggtcc cgccgtgcct gcggcggatc tgccgcacgt cggcgaggtc
     5221 gaggcggacg aacgacaccc gccgggccgt gccgccggac gtgcgcatcg cgggcaccgg
     5281 cggcacccgc acggcgcgtg cgaccgcgcc ggccatggcc gcggtctggc cgatgccgta
     5341 ggacggcggg tccgttgccc tggagtgcgg caggccaccg tcgagcagcg cacccgccag
     5401 cgccaccgca ccggcgccgt cggcgagtgc gtggtgcagc ttcacgagga ccgcgaaccg
     5461 gtcgtcggac aggccggtga cgacgtgcac gtcccacggc ggccgggaca ggtccagcgg
     5521 ggtcgcgagc cagccagccg cgtatgcctc gaacgtgcgc tgcccggcca cctcgtaggt
     5581 gtgcacgtgc ccggccgggt cgaagtccga cgccggccac cacgacggga accagccacc
     5641 gtcgacgcgg agtcccggca gccgggccgc ccgctccacc agcagtgtcc gcagccgccc
     5701 ggccggcacc ggtccccgga acacggcgac ggcgccgagg tgcatcgggc gttcccgggt
     5761 ctccaggctc aggaaagccg cgtccaaccc agtcaatcgg cccatggctt cagctcacca
     5821 gcgttccgtg tcctgcgagt tacgcccatg cgaagccgtg gttgttcacc cttgcgcgca
     5881 ggtcagggga tcacccatat gacgaccttc gagttcggcg cgaccttgct gttggcggtg
     5941 gggctctggc cgatcacccg gccggacccg ccgccgaagg cctggatctc cgcctggagc
     6001 ccgagttgct gcagcgttgc cacggcctgg tcggcggact ggttgccgag gtcgggcacg
     6061 gtcaccgcgt tggacacgat cacggtgacg gtcttgtcgt cgccctcgat cttcgagccg
     6121 atctccgggt cggtgcggat gacccgcccg ccctcgacgt ccgccgagaa ctccgcggtg
     6181 ccctcgaccg gtgtgtaacc gagggcggtg agttcctgga acgcctcgtc ccgcgtcttg
     6241 ttgcgcacgt cggggatcgg cttgggctcc gggcccttgc tgagcacgat gacaacgcgc
     6301 tcaccgatgt tgagctccgt gcccggctgc ggcgagaccg agacgacctt gcccttctcg
     6361 acgtcgtcgt cgtaccggtt ctgcccgtcg tcgcggtccg gctgcaggcc ctgcttgcgg
     6421 atgaggtcct cgacctccgt cgggtcggcg ccctcgcgca cctccggcac cttcggcttg
     6481 ccgagcgaca cgaccatggt gaccgagtcg ccgcgcagca cctcctggcc ctgcgcgggg
     6541 tcggtcctga tcaccgtgcc cgccgcgatg gtgttgtgcc gttcggtctt gatctgcggg
     6601 tccaggtcgt tgtcccgcaa ctttcgttcg gcgtcgtccc tggccatcgc cgccacgtcc
     6661 ggcaccgtgc ggtaccggcc ggaggcgaac caccaggtcg acgtgccgac gagcgcgagc
     6721 accagcaccg cgacggcact ccacagcgcg atcgacccgc cgcggccctt ccgcgcgggc
     6781 ggcggctgcg gcggccggtt gcgtggcggg cgcggcggtg cggcctgcgg ctgctgggac
     6841 gggaacggac cggacacggg tggcacgtac tcggtcgcgg ggccggcgcg gtccaggtcg
     6901 gtgcgcagca tcgcccgcgt gccctgcggc ccgatcggcc ggaaaccacc gggcggcgcc
     6961 tgccgcacga tcgtcgcgcc cgcgggcgcg acgggggcca ccgcggggga cacgacgggg
     7021 gcgttccgga cggtcctctc agcctcgctg gtgtcgatca cgcccgagct gtggcggatg
     7081 gtctccggcg acaccggcat cgtgcggtcg gcgatcgtcg gcgcgggcac cgggaccggc
     7141 acccgcggcg caccgatcac catgcgcagc ttctcgatct ccgagaggaa cgcggcgccg
     7201 tcgaccgggc gctgctccat gtcgcgccgg gtcgcgcgga cgaccaggtc gtccagctcg
     7261 ggcgggatgt tgccggcgag cgtggacggg gcgggcacgt cgtcgttcac gtggcggtag
     7321 gcgacggaga tggcgttgtc gccggtgtag ggcgcggtgc cggtcagtgc ctcgaacagg
     7381 acgatgcccg ccgagtacac gtcgcctgcc gagttcgcgt tgccggtggt gacctgctcg
     7441 ggggagaggt aggcgaccgt gccgaggatg acgctcgcgc tggtggtccc cgcgctgtgg
     7501 atggctctga ccaggccgaa gtcgccgacc ttgaccgtgc tgccgccctc gccgccgtgc
     7561 ccgatgagca cgttctccgg cttgacgtcc cggtgcacca gaccggcgcg gtgcgcggcg
     7621 gccagtgccg agagcaccgg ctccatgatc gcgagcgcgg tcggcacgtc gagcgcgccg
     7681 cgctcgttga tgaggtcgcg cagcgtgccg ccgtcgacga gctccatgac caggtagacg
     7741 agatcaccgt tcggtgactt gtcgacgccc tggtcgtgca ccgccaccac gttcgggtgg
     7801 tggatcttgg ccgccgaccg tgcctcgcgc tcgaagcggt ccacgaaggc ccggtcatcg
     7861 gcgaaccgcg cgtccatcac cttgatcgcc acccggcggt cgagacgcgt gtccagcccg
     7921 cggtacaccg aggacatgcc accgcgggcg agcagcgcgt cgacccggta ccgctgctcc
     7981 agcagcgcgc cgatcaagcc gactcccctt tcgtccacga ccgtgatggt acggagcgcg
     8041 gcgtgatggc gtggcgaagc ggtccaattc gcggagcccg cggagcgaat catggggcgc
     8101 tgtccgggtc acgaccgggt cacgcgggtg gaaaaccctc tgcgcgggac gacctcacct
     8161 gtggcatcgt ttgcggtgtg agtgcgatcc cttccgccga cgacgtgctg ggccccgatg
     8221 tcgaggtcct accgctgccc gatgtggccg accggctggc gctgccggtc acgaaggtac
     8281 ggcaggcgtt gcgggacggt cagctgctcg cggtccgcag gaacggggtg ctgagtgtgc
     8341 cgaccccgtt cctcaccgct gacggccaga tcgtcaaagg cctgccgggc acgatcaccg
     8401 tgctcgcgga cgccggcttc acccccgacg acatgctgcg ctggctcttc gagccggacg
     8461 agacgctgcc ggggggcacc ccgatcgccg cgctgcgcgc gacgggtggc cgtgaggtga
     8521 aacgcagggc tcaggccctg gctttctgac cggccgcccg ggtcacggtc cgctgcgtcg
     8581 cggtccgctg cgtcgcgtcg agtgcgcggc gcagtcgagc ctgctccgcg tcggtgccga
     8641 tgtgcacgaa cccggccagg aacgccagcc gcgcgagcag ccgtccacgg cgggtcggtg
     8701 cggcacgccg agccagcctg cgcgccacgc cggccgaccg cacgggtgcg atccgcccgc
     8761 cggccaccgc ggccagcacc atgacggcga gcagcgcgcc cgcccacccc agtgcggcga
     8821 cgctgacgcc ccgcggccac cccgtcccgg ccacgtaccc cgccgcggcc gccagcacgg
     8881 ccgtacgggc cagttcggcg ccgcccgcgg gtccttcggt cagtgacgcc cagcagccgc
     8941 acgacgagcc acgccggacg gccacgacca cgaagccgag gaacccggcg aacgtgaccg
     9001 cgagcgccac cccggtgacc cggccgccga cgtgcacgac ggccgcggcg agcagcagct
     9061 cccacgcgcc gagcagccgc ccgtggcgcc gcagcgcgga ggtgctccca cgcggcccga
     9121 agacgcgccg cagcgccccg gccacgtgac cggggcgcca cagcttgggt gcgcccgcgc
     9181 tgaccagcag accggccagc gcgagcgcga aaccctgcga cagagcggcc atcacaggtg
     9241 gtcgtagcag tccatgatca cggccatgat cacgccgagc ccggcgcccg cggccaccgc
     9301 cgcgatggcc tccgcggcgg cgatgccgac cgcggccagc gccgcctcca ggtacacgcc
     9361 gccccaccgg gcggcggcga tcagcatcgc cttcacgtcc tgcggcagca tcttccacag
     9421 gcccgcgatc tccttgaccc cgtcctcgcc gatctccacg aggatctcgc cgtcccggcc
     9481 cgcgcacgcg gtgaagtcat cccacgacat ggttcagccc ttccctcacg cggtctgttc
     9541 gagtgcctgg ttcgtcgccg acagcgactc gtgcaacgtc atgccgttgg ccgagaacgc
     9601 ggtgatcagc gggtcaccct cggacaccac gccgacctcc gggtcggcga gcagcaggtc
     9661 ggcgccctgc cgcgacaggg cgtccacgat cgccctgctg ttctcgtcca ggccctcgta
     9721 ccagctgttc acgtgcagcg cgatctgctg gatgtagccc gcgtccgccg cttccggcgc
     9781 gatggcgatg ccttgctgcg cgagcgcgtc ggcgatgccg ccgcctacgt cgcccgtcgc
     9841 cgcgttcccg gtcggctgcc aatcggtgcc gtcccaccag taattgccgt catcggagag
     9901 ctgggctccc tctggcacgg tcatgaagtc ctcccacgtc gtggcttgtg cacggaggat
     9961 gacctttggc agccggacag ggcagtgctg cgggaccggc tcagcgggaa cggggtgcca
    10021 cccgaaaggg cagcgcacgg gccattgcgg agaccgcgat ccgcagccgc cggtgcgtcg
    10081 gcacgacgac ccgcctgccg agcacgtcgt agccggcgtc ggcgatctcg tcgaggatgt
    10141 ggcggtacat ggcggtcgcg gcggcgatgc agggccgtga cctcggcgcc agcagcgcga
    10201 tgcccggttc ggcccgccgg tagaccgcgt gcgtgcagga cacgaggtgg gcgagcgcgc
    10261 gccggatcgg ccgttccgtg cggccggtgc ggtgggcgtg ttcgagcatg gcccggtcca
    10321 ccccgaacgc ggccagctcg tcggcgggca ggtacaggcg gccgcggtcg aggtcctccc
    10381 cgacgtcgcg caggaagttg gtcagctgga acgcctcgcc gagcgcggcc gcgtacggcg
    10441 ccgcctcctc ccgggggccc tcggtgccga gcacgggcag catctgcagc ccgatgaccc
    10501 cggccgagcc gtgggtgtac tcggcgaggt cggcgaacgt ggcgtagccg gtgatcgtga
    10561 ggtccatccg catggacgcg aggaactcgg tgaacagggc ctcgtcgatg tcgtggcgcc
    10621 gcacggtgtc ggtgagcgcc agcagcaccg ggtgcgcggg cggcgccccg gcgaacgcct
    10681 cggcgagcgc cttctcgagc gtggtcagcg cctgggcggg atcacccggc gcgaccgcgt
    10741 tgtccacgat ctcgtcggcc agccgcgcga acccgtacag ggcgtgcacg gacggcctgc
    10801 tcgcggcggg caggaaccgg gtggcgagga agtacgtgcg cccgtaccgc gcgttgatgc
    10861 ggcggcacgc ccggtacgcc tcgtcgagtg ccggggtgct cttcctcccg gcggcgccga
    10921 acagccccgt cacttcgggc agctcaccca ctggcccgcc gggcactcgc cgttctcctg
    10981 cttgtacgtg gccaccagct gggtcgcgag cgcgtacgcc gaaacggggt tctcggcggt
    11041 ggtgacgagc gatgcggtgc acaccgactt ggtggtgccg aggcagccgc gcagctgttc
    11101 cttcgcctgg tcgcgccagt agcgggcgga cgcgacgccg tacttccaca cgctgtcggc
    11161 gtagctgatc gcgtagacgg cgtgcccgct ctcgccttcc ctgcccgact tggtgtcggc
    11221 gggcttggcg gtggcgcgtt cctcgagcgg cttcgcgtcc ggcgggtcgg cgagcgcgag
    11281 cgcggtccac accgcgccgt acgggtggct gccgggcacc gagttggcgc gctggtagaa
    11341 gctcccccac tccggggtgg tgatcgcgca gctcatggtg gccgccgcgc cgggctggac
    11401 cggtccgacg gtctgctcgc agctgccgag cggcgcgttg tcgcccgtcc agtcggcctt
    11461 caggtggacc ttcacggcct tcttggacgg gttggtgatg tcgacgatga gcgtgcagct
    11521 cggcgcgcca caggcgtcga accggttgcc gccctgggtg atcgtggtga gcgcgtcgat
    11581 cgcggtgccc aggtccttcg tggccccgtt cgcgaggtcg gtgtagatct tgttgatgtt
    11641 cgcggacacg tcgctgaccg cgacctggag gtcgcgcgcc ttggtgttct ccgcgctgcc
    11701 gatctcgtcg agcgcgatgg cgaccacgcc gtgcggcgcg tccttcgcga ggtagacctt
    11761 gccgccgtcg acggggacct cgaggccctc gacctcggcg accttggtgg tcttgtccgg
    11821 cagcgcgccg tcgcccttgg tggccttgcc cgcggcctgg ctgaccacgt ccggggtgaa
    11881 gatgtcggcg aactcgatgc cgagcagcac ggtcggcagc ttcacccagc ggttgccgag
    11941 cgcggtgccg tcgccggagc tgacgccgaa gcgggcggcc atggcggccc agaactcggg
    12001 cgcgcccttg aggtacaggg tcttgtcgag caccgtgatc gtcgcgccga gcccgtcgac
    12061 ggtgatggtg ccgaacacct cgctggtgct ggtggcggtc acgtcgacgg tgaacgcgga
    12121 gccgtcggag gccttcaacc cgccctggta gcgggtcgct gcggactccg cgaagctcgt
    12181 gagcgcggaa gcggtcgcct cggccgtggt gagcggcccg atctcgaccc cggacggcgc
    12241 gccaccgacc gcgttcgtgc aggcggtcag cccgagcacg gccaccacga gaaaaggcac
    12301 aaggcggcgc ggcttccgag tcatggtcct ccccatcccg ggtgcgccgt gtggtctgtt
    12361 cggcgcagtt ccgggaggag tatcgcaact catcgcgcgg cgacgcgcgg ggatgagctg
    12421 acggaacgct gacgttgtgc gcccgttacc cgttgggcgg ccagcctgcc cgagatgacc
    12481 accggcggga tgccgacgcc aggtgtggtg ccacagcccg cgagcacggc gttggccacg
    12541 ccgccgacga ggttgcgggg ccggaacgga ccggtctgct gcaacgtgtg cgcgagggag
    12601 aacggggtgc ccgcggcgag tccggccgcg gcccagtccg ccggggtgac gagccgctcg
    12661 acctcgaccg cgtcgtcgaa cccggtgagg ccgcgcgccg cgagcacctg gcccagctcg
    12721 gcgcggtagg cggggccgac ccggtcccag tcgatctcgc cggtctcctg gttggggcac
    12781 ggcgcgagga ccgagatcac ctcgcggccg gaaggcgcga gcgcctgatc ggtcgcggtc
    12841 ggccgggtga ccagcagcga cgggtcgctc atgagcttgc cgcggtgcag gatctcgtcg
    12901 aacgtgcggt cccagtgcgt gccgaagaac accgtgtggt gcccgagctc cggccaggtg
    12961 cgggtcacgc cgacgtgcag caccaccgcg gacggcgacc agcgcggccg cagcggcctg
    13021 cgtggcgtgc ggcccagcag ccggtagctg accggcaggt cgggggtgag cacgatcgcg
    13081 tcacacggga tccgctcgcc gtgcgtggtg cgcacggcgg tcacgcggtc accggtgcgc
    13141 tccagccacg cggcgccggt gccggtccgc accgacccgc ccgcgtcggc cgcggcggcg
    13201 gccatggcct cggcgaccgc accgaccccg ccgcgcggga accacacgcc cgcgacggtg
    13261 tccatgtacg cgatcacgcc gtacgcggcg agcgcctcgg cgggcgcgag acccgcgtac
    13321 agcgactgga acgagaacag ccgccgcagc cgctcgtcgg acaggtaccg gccgatcctc
    13381 gggccgagcc tgccgaaccc gcccatggcg gccaggtgcg cgagcttcgg gccgagcagg
    13441 tcgaggggcg agtcgaagtt ggcgccgatg aactcctcgc gctgcacccg gtacaggctg
    13501 gtgagccact ggcgcagccg caggtacccg gccgcctcgc gcggcccggc cacccgccgg
    13561 acctcctcgg ccatcgcgtc ggcgccggtg tgcacgtgga tcgtggaccc gtcggcgaag
    13621 tgcgcccggt aggcggggtc gaggcgggtc agctcgaccc gttccgcgag cgacgagccc
    13681 accgccgaga acgcctcgtc cagcaggtcc ggcatggtga gcacggacgc gccggtgtcg
    13741 atgcggtagg cgccgagccg gtccgcgccc gcccggccgc cgacgtgcgg cgccgactcc
    13801 agcacggtca cctcgcggcc cgcgccgatc agatgcagcg cggccgagag cccggcgagc
    13861 ccggcgccga ccacgaccac ccggtcggtc gcgccgggga gcgcgcgcat tcagcggtcc
    13921 cgtcgggtgg cggcgatcgc gaggtccgcg agccgcgtgc ggccgggctc gtcgaggccc
    13981 gccgcgtcga gcgcggccat cgccgacacc gtgagcttct cgatccgccg ctccagctcg
    14041 tcgaccgcac cgacctcgac cagcaggtcc cgcacgcgct ggatggtctc ctgcgtcagg
    14101 ccggggtcgc cgagcgcgcg gcgcagcagg tccgcgtcgg cgtgcctgcc cgcctcgtcc
    14161 gcgtagccca gccccagcga gacgagcagc gtgcgcttgc cttcacgcag gtcgtcgccg
    14221 gcgggcttgc cggtcacctc ggtgtcgccg tacacgccga gcaggtcgtc ccgcagctgg
    14281 aacgcgacgc cgacgtcggt gccgaacgca cggaccgcgg cgatcgtgtc ctcgtcggcc
    14341 cccgcgagcg cgacacccat gtgcagcggc cgttccaccg tgtaggcggc ggtcttcagc
    14401 cgcgccaccc ccagcgcgcg ctcctcggac tcgtcgccct cggcctgcgc gagcacgtcg
    14461 aggtactggc cggcgaacat ctccgcccgc atggcgagcc acggcccgcg ggcagcacct
    14521 cgcatccggt ccgacagcgg cgcgccggtg aacatgtcgt ccgcccacgc gagcgccagg
    14581 tcgccgagca ggatcgcggc ggccatcccg aaccgctccg gctcgccgag ccagccgccc
    14641 gcgcggtgcg cgtcggtgaa ccggacgtgc acggtcgggt ggcccctgcg cagctcggac
    14701 gcgtccatga ggtcgtcgtg gaccagcgcg cacgtctgga tcagctccag cgcgctgacc
    14761 gccgtgagca cggcctcggc ccgcgtaccg gtgccttccc cgcccgcggc gcgccagccc
    14821 caccacgcga acgtgggccg gatccgcttg ccgccgcgga gcgcgaagtc ggagagggtg
    14881 tcgacggcgg ccgcgaacgt ctgcgccagc gcgggcagct ccgcgcggcg ctccgccagg
    14941 taaccgcgga ggagcttctc gacatggcgg tgcaccgcca tgtcgatgtc ctctgccatg
    15001 tccgctgcca cgcgctcggg ggtcacgctg accatggtgc gtgttcggat cccggaacgc
    15061 actgccgggg gtgggtgtcg agggtatctg taggcagggt cactaccctg ggtacatgac
    15121 ttcggtggtg gcgcgtattc ccggcgaccg gccggtgttc tccgtcgagt tcatgccgcc
    15181 gcgcgacgat gcggacgaac tccggctgtg gaacgcgatc cggtcgttgg agggccttga
    15241 cccggctttc gtgtcggtga cctacggcgc gggcggctcc agccgcgacc gcaccatccg
    15301 gaccaccggc cgtgtcgtga cggagaccac actggtctcg atggcccacc tgaccgcggt
    15361 ggaccactcg gtggccgagc tgcgcaacgt catcggctgg tacgcctcgc tcggcatccg
    15421 caacgtgctc gcgctgcgtg gcgacccgcc cggcgacccc aacggtgagt gggtcaagca
    15481 cccggagggc ctcgagtacg ccgaggagct ggtgagcctc gtccgttcgc tcggcgactt
    15541 ctgcgtcggc gtgtcggcgt tcccgtacgg ccacccgcgc tccgccgacc tcgacgagga
    15601 cacccggtac ctggtgtcca agctccgcgc gggcgccgac ttcgccatcg cgcagctgtt
    15661 cttcgaggcc gacgacttcc tccgcctgcg cgaccgcgtc gccgccgcgg gctgcgagac
    15721 gctgctgctg cccggcgtga tgccgctgac cacgccgagg atcctgagca agaccgtgga
    15781 actgtccggc gcggacgtgc ccgcgtcgct ggcaggcagg ctcgacccgc tcgccggtga
    15841 cgcgaaggcg ttccgcgagg agggcatgaa cgtcacgacc gagctgtgcg agcggctgct
    15901 ggccgaaggc gtgccgagcc tgcacttcta cacgttcaac cgctccaagg cgacgaagga
    15961 aatcgtcgtc gaccgcctcg gcctggcgcc gggccggtcg cagctgcgtt ccgtcggtta
    16021 gtgctgcggt cgcctacgtt gggcgttcct tcttgcgcgg ggtgacttgt cctcgccgga
    16081 gggcgccccg ccccatccac ggaacctggc gacgtgggtg gacacagcgc tagtagcggc
    16141 cgaccgcctg tgctcggtcg gcgctcaggc ttcgccggtg tgcgatcagc gcgagcagcg
    16201 cggcgatcac cgccgccagc agtgcgccgc cgccgacgat cgtcacccac ttcatcagcg
    16261 actcgccgcc gccgttggag tactccgcga tggcgttgaa ctcggtgacc gcgccgggct
    16321 tcggggacca gctgatcgtg ctgtcgtcct cgtcgccgtc ggttctggtg accgggccgg
    16381 ggaaggcgat cttgatctgg atgtccgcgc ggtccttcgg cacctgcgtc aggtcgaccg
    16441 acccggcgag cgtgacccgg ccacccacgc ggcgcagcga cagccggtac tggttggcct
    16501 cggagatcga ctcgacgagc gtcgccacgt cggtgaaccg cagctccttg aaggtcacct
    16561 tctggccgac gtagccgtcc tgcgtgtact tctccgcccg cacacggtcg ttgagctccg
    16621 gcgggatcgt cagcggcggc ccgttgtcct gttcgctcac cggtaacgcg gcgatgatca
    16681 gctcgcccga gacggtgtcc tccggggaca cggccagtgc ggtgtggatg cggaggcacc
    16741 cggtcagcga aagcatgagc acggcgaaca gcgcgaacag cccggtgacc ctggagaccc
    16801 tgcgcatcgc gccatcctgc cagtagccgt gccgggcgcg aaatcccgtg tgtgcgcagg
    16861 agctgatggg taccgtgccc gccatgaccg tgcaccgcat cagcgacgac tacgtggacg
    16921 actacgtccg gctcgtgccc accatcgcga ccgagctagg cataccgggc tacgacgacc
    16981 agtggccgga cctgtcgccg gagggcaacg ccgcggtggc gggcctggcg aggcgcgcac
    17041 tggccgacgt ctccgccgtg gagccatcgg acgacgcgga acgcgttgcg aaggcggtct
    17101 tcaccgagcg cctcggcgtg gaggtcgagc tgtacgacgc gggtctgatc gactcggacc
    17161 tcaacgtgct cgcgagcccg ccgcagagcc tgcggtccac gttcgacctg atgccgacga
    17221 gcaccgcgga cgactggtcc accatcgcca cccgcctgtc ccgcctgccg gcggcgctgg
    17281 ccgggtaccg cgtgtccctg ctgcacgcgg ccgcgaaggg caacgtctcc gcggtccgcc
    17341 aggtcaccaa ggtcgccgac cagtgccaga agtggagcca gggcttcttc accgacttcg
    17401 tcgcgggcgc caaggacgtc ccggacaccg tccgcacgga cctggacgcg ggcgcggctg
    17461 ccgcgtcgaa ggcgtacggc gagctggcgg agttcctccg cgccgaggta cttccgaagg
    17521 ccccggggaa ggacgcggtg ggcgcggagg cgtacaagct gttgtcccgc cggtacctcg
    17581 gtgccgcact ggacctgcgt gaggcctacg agtggggctg gaccgagttc ctgcgcctcg
    17641 aggcggagat gaaggaggtc gcgaaccgcg tcaagccggg cgcgagcctc gcggaagcgg
    17701 cggcggcgct ggacaacgac ccccgctacc aggtgcgggg cgtcgaagcg ttccgcgagt
    17761 ggatgcagaa gctgtccgac caggccctgt ccgacctgcg cggcgtccac ttcgacatcc
    17821 cggacgagat catgcggctg gactgcaaga tcgccccgcc cggcggcacc gcgggtgcct
    17881 actacacgaa cccgaccgac gacttcagcc gcccgggcgc catgtggtgg gccctgcccc
    17941 cggacaagga cgagttcacg acgtggcgcg aggcgagcat cgtgtaccac gagggcgtcc
    18001 cgggccacca catgcagatc gcgacggcca tgtaccacgc ggaacggctg aacaagttcc
    18061 agcggatgct gtcgtgggtg cccgcgtact cggagggctg ggccctctac gcggaacgcc
    18121 tgatgcgcga gttcggctac ctgtcggacg acggcaacct gttcgggatg ctcaacgaga
    18181 acatcttccg tgccgcccgc gtgatcatcg acatcggcat gcacctggaa ctggagatcc
    18241 cggcgggcac cggcttccac gagggtgcga ggtggacccc ggacctgggg ctggagttca
    18301 tgctgacccg cacgatcacc gaacacgagc tggtggtcga cgaggtggac cgctacctgg
    18361 gctgggcggg ccaggccccg gcctacaaac tgggcgaacg cctgtggctg gaagcccgcg
    18421 acgacgcgaa ggcgcgggcg ggtggcgcct tcgacctgaa gcacttccac atggagtccc
    18481 tctacctcgg ccagatgggc atggacacga tgcgcgagtg cctgtccagg atccagtagc
    18541 cgaagccgac gccacgaagg gcgccttcag gacgacctcc cgtccaggag gcgcccttca
    18601 cggcatcgac ggcacgccac cccgtgcgag accggcgacc tcggcgaacg cccacggatc
    18661 gtgcgcggag aacacccgca cctcatcccc gtgctcccgg accagctccc gcaacctggc
    18721 ctggttcccc acccgcaacg gccggtccac ttcggtcacc tcctcgaacg cgtcccacag
    18781 aggaatcgcc cagcggtcac tggtgatctg cccgtcgtaa taaaacgcat cgccggcgtg
    18841 cagcagccat cggtcagcgg ttcggaccgc caccgcgcag tgcccggcgg agtgcccggc
    18901 gaggggcacc agcaacaact ccgatggcag tccgtccagc cgcacggcgt cgaacccgaa
    18961 ccacgacacg tcccgccgtg acggataggt cacccagcgc ggccgatgag cccagtgcgc
    19021 gggccgggta ccgcagcgtg tgctcgggat gtgcgtcgga gacggccatg gccgcccggt
    19081 actcggcgtc gtgcaggtgc acccgcgcgc cggggaagtc cggcaacccg ccgctgtggt
    19141 cgagatccag gtgcgtgagc acgatgtccg tgacgtcgga cggcgcgtac ccacgcgcga
    19201 tgagctgggc cgcggcggtt tccgacggag agagcaccgg cgccgtgcgc tccaggaacg
    19261 cgtcgccgag cgcgaccgaa ggctgcgtca cgtccacggc tccgaaaccg gtctccacca
    19321 gcaccagccc gtgctccgcc tcgatgacca ggcagtggca cacgacccgc gcgggctccc
    19381 ggccgtcggc ggggatctca cgcatggtgc cgcagttgag gtgtgtgacg ttcatcgtgc
    19441 tcccggttcg gccgttcggt tggtctttgc cacaaagaaa tgtgaaaaca gcgaaaatca
    19501 ctcgctttgt ccaccgaatg gggcaattcg gtcgtctgct agccctgccg acgcagccgg
    19561 gcacccccgt tcggaggaag cggtagcgtc agatcacgtg ctccagcata taatatgacg
    19621 actggtctac cgaattcaat agaccggtca tcatagatcc cgggaaacat cgtgaccggt
    19681 gcttgcgcga cgcgagatag tggaggcaag tgacacccag tggaggtcgg caatggcaac
    19741 cgacgcggaa gtcatcggcg tccgcggcgt gttcctcaag ctgaggaccc atgccggcct
    19801 gaccgcgaga cgtctgcgcg acaccgaggt ggacacgcgc gtcctcgcgg acctgcccgc
    19861 ggtccagcgc gccatccggg agtccggcgc accggtcgag caggccatcg tcgacgcggt
    19921 ggccgcggtc gtcgccgagc tcgaccccac cgaccggctc atcgccgacg tggtgctcgc
    19981 gctgggcatg ctggcggacc ggctcaccga ccagcccgcg ctcgccaacc gcctctaccg
    20041 cgccgacctc ggcgtgcggc gggtggcgct gtcggagggc tgggcgacgc tgcacgagct
    20101 gatgggcgtc gagcacccgc cgcaggcgcc caccgtgcgc agcctgcgcg gttcggtgga
    20161 ggagaagacg ctgggcgtgc tggccgagcg ctgcgtgcgt gccgcgggca tggcccgccg
    20221 cgagtcgacg gaggagccgg gcaacgcggt cgtggtggtc ggcggcgccg tgatggacca
    20281 catcaccgtc gtcgagtccc tgccggtggc gggcgagtcg gtgcaggcca cgtcgttcca
    20341 catgaatccc ggcggcaagg ggctcaacct cgccgtggcg ggcaggcgca tgggtttcga
    20401 cgtccggttc gccgccgccg tgggcgacga cgcggccgct accaggcttc tcgagtacat
    20461 gtccgagcag aacctgggca ccgacttgat cgttgaagca ccgggcgaag cgacccccgt
    20521 ggcacaggtt attgtgctgc ccaacggaga cgccgccacg atcggctgga agaacgagct
    20581 ccgggtcgca ctctccacaa gagacatgcg aagtcaggcg atgagccgtg cgctggccga
    20641 ggccgacgcc gtgctcgtga ccctggaagc gccggtcgat gtcgtgaagt ggactttgga
    20701 caccgcacgg actctgccga ggaaaccgct ggtgctgttg caggcgtcgc cgccgctgga
    20761 ccgtccacag cagatctacc ggcagttgac cggagtggac tacgtcgtgg ggtccgaatg
    20821 ggctctgagc aagctgctgc cccccttcaa cgacgacaag agcattgacg agatagcgcg
    20881 ccagctgcgc actatgggcg tggcgacggt ctgtgtcgtg gagaacttcc gctgccggat
    20941 caggtctcgt gagttggaag cggacttcga cgcaccgtcg gtgccgctca ccgattcccc
    21001 gggggccaga gaagccttct cagccgccct gatacatcat ttgctcagga tcggacgcgg
    21061 tggcctcacc cgcgaaagcc tcgagtgggc gagcgcggcg atggccacga acctttccat
    21121 cgacatcatc acagacgcca tgccgaagcc cggcgacgtc ggacggatca tggagtcgga
    21181 ccagagtgtg gggtagcccg agtgggcgat gtaaacctga cggaacatga gctgaggcac
    21241 gcagacgggg acttccgcgt cgtcgtgctc ggccgcggtt ccgacatgca cggcaaccag
    21301 ccgtgcgccg cggtgttcgg cgaacccggg aacgggtgtc tcgttcgaat tcactcgcgg
    21361 tgtgtgtacg gcgagatctt cgagtccgtc gactgtgact gccgggacca actgcgacag
    21421 tcgatggcca tgatgcgcaa ggtgggctcc ggtgtcctca tctacctcga ccaggaggga
    21481 agaggcgccg gactgctcgc gaaggctctc gggtaccagt tgacccagcg tgagggcctg
    21541 gacacgttct ccagctaccg ggtgctcggc ctgccggagg actcacgttc ctatgaggac
    21601 gcggtggcga tcctccgcaa cctcggcctg cgccgggtgc ggttgctcac caacaacccg
    21661 gcaaaggtcg cggcactgtc cacggcggac ttccaggtcg agcaacagcc cttcctggtc
    21721 cgcgggcaga gcgcggaggc ccgccggtac ctggcggcca aggccaggtt cggtcacacc
    21781 atctcgatcg ccgagctgga agccgacgcc gcgcgcgacc gctggcggtg gctgcacaag
    21841 ctgctgcggc ggacgtggcg caagccggcc caggaaacgc ccgagcgggc acccgcgcgg
    21901 gtcgtggaac tgccggtacc cacggtgaac cccgtggagc agtcggtcac gtcggcacaa
    21961 ccgaccgacc tcgtcagctg atgcggtggc cggggtggcg aaccatcccg gccacctgaa
    22021 cccgaggatc gccgcgcccg cgtcgcgtgc gcactgtcag ttccggggcg gcgggacggg
    22081 cagcacacga cccagtacgc cgaacggcct ggggtcgccc gtgaaccggt agtggcgcag
    22141 cacgtcggtg aagcccagcc ggtagtacaa ccgccaggcg cgggtcgggc cctccggggt
    22201 cgacagcagc accttcgacg cgcgcacccc gcccagcagc ctgcgcagca gctcctcgcc
    22261 gatgccccgg ccctggctcg cgggcgagac gtgcacctcg gtcagctcga agtagtcctc
    22321 cagccagcgg tccgccagtt ccgcgccgga ctgctcgatg atcccgcggc gcacctgctc
    22381 gtgccaccac tggcccgcgg cgccccggta gccgtacgcg acacccacca tgcggtggtc
    22441 ggcgttgaac gcgccgacac agcgccactc cgcgcgcagc atgtgcgcga gccacatggg
    22501 tgcgcgctgt tctgcggtgc ccgacgggta acgcatcgcc gtgacgtaca gcgacaacgc
    22561 ttctggcagg caggcgcgca gttcgtcggg ggagaggtcg acgaaccgtt ctacgcgtgg
    22621 tgggaccgcg gtcacgacag ccgattctcc tctcagcccg cgacgtccgc agccgtgccc
    22681 cccgtcaggg cgaccagatc ggcgtaggtc gtcgggaaca ccgacttcgg gtggcctgcg
    22741 gccgcccaca ccacctcata gcgtgccagg tccgcgtcca cgaccgtgcg caccgggtgc
    22801 gggtgtccca ccggcgccac cccgccgatc gcctgccccg tgtgttcccg cacgaaggcc
    22861 gggtcggcct tgcccacctc gtccgcgccg accagcgcgg cgagcgtcgc ggtgtccgcg
    22921 cggtgggcgc cggaggtcag cgcgagcagc gggcgcacct cgtcaccgta cgtagcacgg
    22981 aagacgaggc tgttggcgat cgcaccgacc tcgacgccga gcgcctgcgc ggccgccgcc
    23041 gcggtgcgca cctcgtcgtc gaggaggcgg atgccgtccg cggccgggga gaggcctgcc
    23101 tccagcagcg cggcggccag tttgctgatc gaggggtggt ccagagaggt catggcccta
    23161 tctgaccacg gatgcggttc tgatcgccgc cgaaattccc ggtcgaggtt gagtctcccg
    23221 gcagccggag ctaagctcga actgttcgaa cacccgttcg aacactggct cggtggcagg
    23281 acgggggaag cgtcttgcca ccgagccccg ccggcttccc cacggcacat cgtcacagcc
    23341 agtgatgatt ttccgatccg cgaggagatc cggtgactgc gactctcgac tttccgaacc
    23401 accactcggc gacgcccgag tccgcgctcg gcctgctcgc ccaggccgag accggactct
    23461 ccaccgccga gctggaggag gacgcggcgc gccggttcgc ggacgcctat ctcgcggcgt
    23521 tgcgtgccgc cgcggcgctg ctcgccatgc gcgggcggcc gcaccgcgcc cggtcgcgcc
    23581 cgatgagcgt gtggacgctg ctgtcgtcgg tcgcgcccga gctgcgggag tgggccgcgt
    23641 tcttcgcgtc ctgctcggcg acgcgcgcgt cggtgcaggc gggcatcacc cgtgcggtca
    23701 gcacccggtc cgcggacgac ctcgtgcgcc agtccgggca gttcatcgag ctggtgtcgc
    23761 ggttgatccg cggcgcggac cggtgaccgt cacaccactg gtcgacttcg cccgtctgct
    23821 cgacgtgctg gacaccgagg gggagcggct cgccacgtcg gccacgggaa cggatccgga
    23881 gctcgaggtg ccccacctgc cgggcatgcg gctcggtgag gtggtgcggc acgtcggctc
    23941 cgtctaccgg atggtggtgt cctggctgcg cgacggcgag cggcccaccc gctggcagcg
    24001 cgagcccgcg ccggaccaga gcgtcgtgga ctacttccgc gccggcctgc tggaggtcgt
    24061 cgacgaactg gaccggcacg acccgctcga gggtgcgccc acctggtggc cggagcacca
    24121 gaacttcggt ttctggtgcc gcaggctggc gcacgagacc accgtgcacc gtgtcgacgt
    24181 ccagctgacc ggcgccaaac tgctggtcgg cgacatcgcg gcggaggtgg cgctggacgg
    24241 catcgacgag ctcatgtcgc tgtggttcac ccaccgcctc ggcgtgctgg gcgtgtcgga
    24301 cgtggtcccc ggccgcgtgg ccgtcaacgc gggtggtcgc cgctggatcg ccagggtctc
    24361 caccaccggc gcctcggcat ggcgcaccga cgaggacgaa ccggccgagg ccacggtctc
    24421 cagcgacgcg acgggcatgt acctgtggct gtggggcagg cgccctggtg cgtacgtgca
    24481 ggagtcgggc gatccggcgc tggtcgcgca gctgagatca ctgctccgcg tcgcgacgcg
    24541 ctgaattgtc ggtgccttcc gctagtttgc tgcgcatgtc cacgcgactg tgcaacgtgg
    24601 tggtagacgc ggccgacccg acggccctgg cggagttctg ggtgaccctg ctcgactggc
    24661 gcgtgtccca tgcggacgcc gaggaggtgg acgtcgtcgc gccaccggac gacggctgga
    24721 agttcgacct ggtcttcgtc ccggtggcgg accagaaggt gggcaagaac cgggtgcacc
    24781 tggacctgtc gagtgcctcc ccggaccacc aggcggcgat cgtcgcccac gcggaggcgc
    24841 tcggtgcggt tcgcgtcgac gtcggccagc gcaacgtgcc gtggatcgtc ctggccgacc
    24901 cggagggcaa cgagttctgc gtactggaac aacgacccga gtacgcggcc accggtgcga
    24961 tcgcggcggt ggtggtggac gtggtggacc cgttgcggca gtcggagttc tggtccggcg
    25021 cgtcgggctg gccgg
//
