LOCUS       NZ_JACHJK010000013     22205 bp    DNA     linear   CON 29-SEP-2024
DEFINITION  Streptomyces echinatus strain CECT 3313 Ga0436950_13, whole genome
            shotgun sequence.
ACCESSION   NZ_JACHJK010000013
VERSION     NZ_JACHJK010000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces echinatus
  ORGANISM  Streptomyces echinatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 302204)
  AUTHORS   Whitman,W.
  TITLE     Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the
            genomes of soil and plant-associated and newly described type
            strains
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 302204)
  AUTHORS   Whitman,W., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2020) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 160.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014203595.1-RS_2024_09_29
            Annotation Date                   :: 09/29/2024 05:39:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,466
            CDSs (total)                      :: 8,381
            Genes (coding)                    :: 8,094
            CDSs (with protein)               :: 8,094
            Genes (RNA)                       :: 85
            rRNAs                             :: 7, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 5, 1 (5S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 287
            CDSs (without protein)            :: 287
            Pseudo Genes (ambiguous residues) :: 0 of 287
            Pseudo Genes (frameshifted)       :: 116 of 287
            Pseudo Genes (incomplete)         :: 236 of 287
            Pseudo Genes (internal stop)      :: 12 of 287
            Pseudo Genes (multiple problems)  :: 77 of 287
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:56:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 214110
            Orig. end                         :: 236315
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JACHJK010000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22205
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22205
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22205
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12205](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12205)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            588..1838
                     /locus_tag="FHS34_RS31270"
                     /old_locus_tag="FHS34_006335"
     CDS             588..1838
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675708.1"
                     /locus_tag="FHS34_RS31270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006335"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_184971666.1"
                     /transl_table=11
                     /translation="MGPLPELRYPSVPELVASARALAGREPGLCALRQVGVSRAGRPLH
                     LLSVGHARRAVLVVAGAHANEPTGGSTLRALAERVLVDRELRTGTSWHFLLCADPDGAS
                     LHVTPAPRSLLDYHLGFYRPTGAEQPEWSPSVLPPDRLPPETRALTGVIDELRPYLQVT
                     LHGTDLGGSWVQLTKDVPGLAEPFAKSAAELHIPVETGASDAAGWPASGPGVHVMPGPE
                     TGVAYPSMPDDARHSTWYHAHRYGGLTAVVEVPMWASDLVDDPAPHPAPAAAMRRLSAR
                     LLRDAREVERILAEALPRLDGADGPLLRAARWALELIPGLAEDWIHTAPAGTTMAYVGS
                     VDAFGRRLPLRAAAMLLRVLREADDRAAPRLEQLVSTWCDAFAQRFRARWVPLEHQVEH
                     QSRTVLVAAHQAREQAS"
     gene            complement(1894..2307)
                     /locus_tag="FHS34_RS31275"
                     /old_locus_tag="FHS34_006336"
     CDS             complement(1894..2307)
                     /GO_function="GO:0004867 - serine-type endopeptidase
                     inhibitor activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071457.1"
                     /locus_tag="FHS34_RS31275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006336"
                     /product="SSI family serine proteinase inhibitor"
                     /protein_id="WP_184971668.1"
                     /transl_table=11
                     /translation="MTHITRTAAAAGALLAAAGLLTAGPARAASPDNQQGNWLYLTVTR
                     GDARTGVTHGALLLCDPPRGHAHAAQACGELADVQGDIDRIPAADVFCPMIFAPVTTHA
                     RGRWNGRSVDFTETYTSVCVMNARTGHVFALDG"
     misc_feature    complement(2329..2338)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(2444..2995)
                     /locus_tag="FHS34_RS31280"
                     /old_locus_tag="FHS34_006337"
     CDS             complement(2444..2995)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385491.1"
                     /locus_tag="FHS34_RS31280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006337"
                     /product="DUF1707 and FHA domain-containing protein"
                     /protein_id="WP_184971670.1"
                     /transl_table=11
                     /translation="MTSSFEFSTYPARLSDAERDKALRVLRDGVALGRLSHDTFVRRME
                     LALAARRSDELAALVADLPQENRFSRAVLGTVEAVSGFTVRLRRAWQAERLPKLLLPHP
                     AHTHPLRIGRDPANGLRLNHETVSRVHAELRRQGGLWVLRDLGSTNGTTVNGRRVTGAV
                     VVREGDQIAFGRMAFRLSAS"
     gene            3173..4918
                     /gene="treZ"
                     /locus_tag="FHS34_RS31285"
                     /old_locus_tag="FHS34_006338"
     CDS             3173..4918
                     /EC_number="3.2.1.141"
                     /GO_function="GO:0033942 -
                     4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675705.1"
                     /locus_tag="FHS34_RS31285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006338"
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="WP_184971672.1"
                     /sec_met_domain="CBM_48 (E-value: 2.2e-06, bitscore: 21.9,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 1.5e-14, bitscore:
                     48.3, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFEVWAPQAERVTLHCEGATRALARDPARAGWWTGEAEAEHGAR
                     YGFALDDGPVRPDPRSRRQPDGPDGLSAVVDHGRHEWRARWAGRGLPGAVLYELHVGTY
                     TREGTLDAAADRLDHLVELGVTHVQLMPVCPFPGRHGWGYEGVSLWAVHEPYGGPEALK
                     RFVDRAHGLGLGVVLDVVHNHLGPSGNHLPAFGPYFTDTHRTPWGSAVNLDAPGSDEVR
                     AFLLGSALAWLRDYRIDGLRLDAVHALYDTRACHFLEELSAAVDGLAGEVGRPLFLIAE
                     SDMNNPRFITPRAEHGIGLHAQWNDDFHHALHTTLTGESQGYYADFAREPFAALTKTLT
                     GGYFHDGTYSGFRGRRHGRPLDRARVAGHRLLGYSQTHDQVGNRAQGDRLAAHLSPGLL
                     ACAATLTLTAPFTPMLFMGEEWAAGTPWQFFTDHTDPGLAEAVRQGRRREFAAHGWAEE
                     EVPDPQDPATRERSCLDWSEPEREPHARVLAWYRRLVALRRAQPDLTDPDLADTKVAYD
                     EEARWLAFRRGDVRVAVNLGKEPAAIPLGTGRVEVLAAWDPVTAPGADGLLLVPGESCV
                     VLAQP"
     gene            complement(5185..6120)
                     /locus_tag="FHS34_RS31290"
                     /old_locus_tag="FHS34_006339"
     CDS             complement(5185..6120)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675704.1"
                     /locus_tag="FHS34_RS31290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006339"
                     /product="phosphotransferase family protein"
                     /protein_id="WP_184971674.1"
                     /sec_met_domain="APH (E-value: 7.2e-18, bitscore: 59.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAPTPTVDTVRRLVRSLLKEGGDGTGGPEVRPVTEDREHTWWI
                     GGRHVLRLAPDREASVRRRRELRLRDLVRPHLPVAVPTSVAHGDWAPGLAYTLDTRVPG
                     GTADEYDVSAVGEADLAGLLGGLRAVPARQAETLGVPRTAPRSLEALRRMAVHAAERLA
                     AADEFDAARLHQLTPPGAAQLAAQPGTAVLTHHGLTGAHVVVSDDGRVRGILDWTAAAL
                     GDPAEDIAGLAVAVGSPAAVRAATLAGYGARPCLRGLWLARCDTVIRLTDRLEGRTDGP
                     LPLLRTQLRRVWEPILLERVTDFKEDDPEP"
     gene            complement(6174..7301)
                     /locus_tag="FHS34_RS31295"
                     /old_locus_tag="FHS34_006340"
     CDS             complement(6174..7301)
                     /EC_number="3.4.11.9"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996926.1"
                     /locus_tag="FHS34_RS31295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006340"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_184971676.1"
                     /transl_table=11
                     /translation="MTGTTPAPFTAADHRARMERAVRSAADAGLAGLLVAPGPDMVWLT
                     GYTPTAVTERLTVLVLAPGRDPVLVVPALEAPDAEHAAGAAALTLRDWTDGKDPYAVTA
                     GLLDGRGRYGISDNAWAMHLLGLQRALPETSYAALTDALPMLRAVKDAAEVELLAAAGA
                     AADQAFEAIRKVPFAGRRESDVGHDLAGLLTRFGHSQVDFTIVGSGPNGANPHHEVGDR
                     VIRTGDMVVLDFGGLKDGYGSDTTRTVHVGEPTEEERRVHDLVRAAQEAGFRAVRPGVA
                     CQEVDRAARAVITDAGYGAYFIHRTGHGIGVTTHEPPYMIEGEELPLVPGMCFSVEPGV
                     YLPGRFGVRIEDIVTVTEDGGRRLNNTTREMVIVD"
     gene            complement(7519..8082)
                     /locus_tag="FHS34_RS31300"
                     /old_locus_tag="FHS34_006341"
     CDS             complement(7519..8082)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675702.1"
                     /locus_tag="FHS34_RS31300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006341"
                     /product="PDZ domain-containing protein"
                     /protein_id="WP_184971678.1"
                     /transl_table=11
                     /translation="MEQTALRPKPMPGQDRRDDDTPGPARRPHAARRRGRRLRTLLFAL
                     CTATVLVLSGVGVGTVGATVIGLSRLAELRRQAPPSAPAAKTPPSAAPDPGRAPHGMTL
                     GLEVVDAEKPGALVVGVHVPGSGYTAGLIRGDVVLQFGSARVDTAADLVRAVTRARPGE
                     AVLLTVRHSEGGYQQLTVTPAVAV"
     gene            complement(8377..9888)
                     /locus_tag="FHS34_RS31305"
                     /pseudo=""
     CDS             complement(8377..9888)
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431964.1"
                     /locus_tag="FHS34_RS31305"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="multicopper oxidase domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTEIIGRLVGETTADRAAKRPENNELMPYVAPLTVPPVLRPAAGD
                     VRCETEIALRPARVRLHPQLPPTLMWGYDGQVPGPTIEVRRGQRVRIAWTNRIPKDGEY
                     PVTAVEVPRRTDGRPQATTEPGREGVEPNKDVAALPAWVVTHLHGAQTGGGNDGWTDNG
                     VGPATPSCRSTRTTTGRSSGGTTTTR"
     misc_feature    complement(9694..9696)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9875..9888)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.28"
                     /tool="antismash"
     gene            complement(10001..12205)
                     /gene="cyc2"
                     /locus_tag="FHS34_RS31310"
                     /old_locus_tag="FHS34_006346"
     CDS             complement(10001..12205)
                     /EC_number="4.1.99.16"
                     /EC_number="4.2.3.22"
                     /EC_number="4.2.3.75"
                     /codon_start=1
                     /gene="cyc2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019981792.1"
                     /locus_tag="FHS34_RS31310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006346"
                     /product="germacradienol/geosmin synthase Cyc2"
                     /protein_id="WP_184971681.1"
                     /sec_met_domain="T1TS (E-value: 3.1e-81, bitscore: 267.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFELPHFYMPYPARLNPHLDEARAHSTRWAREMGMLEGSGIW
                     EQADLEAHDYGLLCSYTHPDCDGPALSLITDWYVWVFFFDDHFLDMFKRTPDRAAGKAH
                     LDRLPLFMPLDPSTAVPEPENPVEAGLKDLWERTVPSMSVDWRRRFSVATEHLLNESMW
                     ELSNIHEGRIANPVEYIEMRRKVGGAPWSAGLVEYATAEVPASVAGTRPLRVLMETFAD
                     AVHLRNDLFSYQREVEDEGENSNGVLVLEKFFGCTTQEAADTVNDVLTSRLHQFEHTAL
                     TEVPAVALEKGLTPGEAAAVAAYTKGLQDWQSGGHEWHLRSSRYMNQGARSGSPWQSPS
                     GPGTSAADVGALLAAAARDRLRAYSHVPHQKVGPSRIPDLHMPYELGLSPHLDGARGRL
                     LDWCHRMGILREGVWDEDKLAAYDLALCSAGLDPDATAEALDLSAQWLAWGTYGDDYYP
                     LVYGHRRDLAAARLTTARLSECMAVEGEPAVVAGDAMERGLIDLWTRTTAGMTAGQRRT
                     LKASVDAMTESWVWELSNQLQNRVPDPVDYLEMRRSTFGSDLTLSLCRMGHGPAIPPEV
                     YASGPVRSLENAAIDWACLVNDVFSYQKEIEYEGEIHNAVLVVQNFFGVDYPDALRVVH
                     DLMTQRMEQFQHVIAHELPVLCDDFGLSADARTAVGAYVLDLQNWLAGILHWHREADRY
                     KAAWLGRRAHGFLPDHPPVAPVPAPVVPARAPAVPVLARG"
     gene            12360..13178
                     /locus_tag="FHS34_RS31315"
                     /old_locus_tag="FHS34_006347"
     CDS             12360..13178
                     /NRPS_PKS="Domain: Abhydrolase_1 (20-149). E-value:
                     4.5e-22. Score: 70.8. Matches aSDomain:
                     nrpspksdomains_FHS34_RS31315_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657048.1"
                     /locus_tag="FHS34_RS31315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006347"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_184971683.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.2e-20, bitscore:
                     68.2, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 7.9e-19, bitscore: 62.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSFVLPHEVHGDGAHKVFAVHGWFADRSAFAAVLPDLDRTSFSY
                     ALVDLRGYGEARDATGSYTTAEAAVDLVELADRLGWARFSVIGHSMGGAVAQRLLTVAP
                     HRLRRIAGVSPVPASGMPLAGEQAVLFADAAHRAENRRTIIDFTTGGRRPAAWLDRMVD
                     RSLERSDAKAFRAWLDSWAGDDFSTDVEGSEVPALAVAGELDPALSPEVMRQTWMSWYP
                     RARLAVLPGAGHYAMDETPLELVRTVEDFLRADDADGTDAAPGAARGEPA"
     aSDomain        12420..12806
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FHS34_RS31315_Abhydrolase_1.1"
                     /evalue="4.50E-22"
                     /label="FHS34_RS31315_Abhydrolase_1.1"
                     /locus_tag="FHS34_RS31315"
                     /protein_end="149"
                     /protein_start="20"
                     /score="70.8"
                     /tool="antismash"
                     /translation="VHGWFADRSAFAAVLPDLDRTSFSYALVDLRGYGEARDATGSYTT
                     AEAAVDLVELADRLGWARFSVIGHSMGGAVAQRLLTVAPHRLRRIAGVSPVPASGMPLA
                     GEQAVLFADAAHRAENRRTIIDFTT"
     CDS_motif       12615..12650
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHS34_RS31315_0001"
                     /evalue="4.20E-04"
                     /label="NRPS-te1"
                     /locus_tag="FHS34_RS31315"
                     /protein_end="97"
                     /protein_start="85"
                     /score="12.9"
                     /tool="antismash"
                     /translation="VIGHSMGGAVAQ"
     gene            13175..14440
                     /locus_tag="FHS34_RS31320"
                     /old_locus_tag="FHS34_006348"
     CDS             13175..14440
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983605.1"
                     /locus_tag="FHS34_RS31320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006348"
                     /product="cytochrome P450"
                     /protein_id="WP_184971685.1"
                     /sec_met_domain="p450 (E-value: 3.2e-18, bitscore: 59.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVREAPPVPDVFDPRRYAAGVPYDDYRVLRDHHPVAWQEEPEVL
                     GWPAGPGFWAVTRHVDVVRVLKDAGTYSSYAGATQIRDPDPEDLPFIRRMMLNQDPPGH
                     GRLRRLVSRAFTPGRVERFAAVARERARALLAGALAQAREGDGTVDLVSAVTDEYALLN
                     LADLLGVPESDRRLLLRWTQRVIGYQDPDEAGPPVRDGAGRPVDPRSPAMLRDMFDYAG
                     QLAAFKRRCPADDIMTSLGHEAELAGAELEMFFFLLTVAGNDTVRGAAPGGLLALAEHP
                     EAYETLRAKKAGLASAGDELLRWHPPVLTFRRTAVRDTELAGRRIRAGDKVVVFHASAN
                     RDERVFAAPERLDLTRSPNPHVSFGDGPHVCLGTHFARLQLRLLHEEVLRVLPEPPRLA
                     GPAGRLVSNFINGVKSLRVHLA"
     gene            complement(14417..15616)
                     /locus_tag="FHS34_RS31325"
                     /old_locus_tag="FHS34_006349"
     CDS             complement(14417..15616)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034217.1"
                     /locus_tag="FHS34_RS31325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006349"
                     /product="damage-control phosphatase ARMT1 family protein"
                     /protein_id="WP_184971687.1"
                     /transl_table=11
                     /translation="MPDTPFAPVILGNEPGSFPHSVLAERHPAIIGQVRDAFPYGPGQH
                     RALDELLRSCTEGTIEPLPADAPDRDRWHGWGLAGHTGRPWFDAPWLWSESYFYRRLLD
                     AVGWFGPGPWQGVDPFRPFKRAELDAPETDEELAALDGLRDLPEQERAKALLHGSLWGN
                     RADLGFRLSAAGAEAREASPGLVADDSDVLWSLLPPDETGTLVLVADNAGRELVPDLLL
                     IAHLLAGGRTARAVLHVKPYPYYVSDATTADVVDALRRLRTAGGAAAEHARVLWSAMAD
                     GRLAVRAHPFSCAPLPYADMPDDLRAEFAAATLTIVKGDLNYRRLVGDRRWPPTTPFRR
                     TTAYFPGPVAALRTLKSDVITGLSAATEAALVAAGEQSWRTSGTHALIQADPSGQVHPE
                     "
     gene            complement(15639..16286)
                     /locus_tag="FHS34_RS31330"
                     /old_locus_tag="FHS34_006350"
     CDS             complement(15639..16286)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675696.1"
                     /locus_tag="FHS34_RS31330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006350"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_184971689.1"
                     /transl_table=11
                     /translation="MARQLRAEQTRATIITAAADLFDQRGYESTSLSDIVAHAKVTKGA
                     LYFHFAAKEDLAHAILQLQSRAAQRVVADAESRGGSSLEALMRTTFGIARLAVEDPVPR
                     AGLRLATADIAVRPPLRHPFTEWLDFATRKFTGAVREADLHGDVDVGVVAHSLVCFFIG
                     TRVAGRSLEPVGRLPRRVAEMWHLVIRGLVPVHRRPRYVTLATQLEREVRTA"
     misc_feature    complement(16272..16274)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16726..17655
                     /locus_tag="FHS34_RS31335"
                     /old_locus_tag="FHS34_006351"
     CDS             16726..17655
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125293.1"
                     /locus_tag="FHS34_RS31335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006351"
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="WP_184971691.1"
                     /transl_table=11
                     /translation="MTRMTARLSVRATAAAAPLLLLPWAAGPAQAHGAPTDPVSRVYAC
                     SPEGGAAGSAACRAAIAANGAPFTAWDNLRVAGVGGRDRQMIEDGRLCSGNLPAYRGLD
                     LARRDWPATRLAPGGRLTLAYASTIAHTGTFRLYLTKQGYDPSRPLTWSDLPERPFAEI
                     TDPPLRDGAYRMSATLPADRTGRQVLYTIWQNSSTPDTYYSCSDVVFPRHGKAAGVTRS
                     RRPAATPAAPAAASPRPARTAGSPVESPASGPERGDGRPERAAAAATPVARATHGGSGP
                     SVSLLAGGATAVLLLTGGAALALRLRRR"
     gene            complement(17674..18324)
                     /locus_tag="FHS34_RS31340"
                     /old_locus_tag="FHS34_006352"
     CDS             complement(17674..18324)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675693.1"
                     /locus_tag="FHS34_RS31340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006352"
                     /product="Tat pathway signal sequence domain protein"
                     /protein_id="WP_184971693.1"
                     /transl_table=11
                     /translation="MRTRSLLALGGAATALALAWATPASAAGTVLTTGSTGGTAVAVGD
                     TLTAPLASGTSATFYSSATGTSGVKCTGSQFTATVTGNPTAPGTATESVTAHTFNSSTC
                     TSNVTGVLGVNGITINNLPYSATITSGGDLTVSPPSGSAIQATVQLRTLLGTVTCVYQA
                     PALSGKADNADSSITFTNQRFTKTSGSSLCFANGYFTAKYAPVTDAGVRVYVN"
     misc_feature    18752..18767
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.58"
                     /tool="antismash"
     gene            18948..19646
                     /locus_tag="FHS34_RS31345"
                     /old_locus_tag="FHS34_006353"
     CDS             18948..19646
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996942.1"
                     /locus_tag="FHS34_RS31345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006353"
                     /product="DUF6230 family protein"
                     /protein_id="WP_184971829.1"
                     /transl_table=11
                     /translation="MASSPDVPSVGNTPENPGSDTPPEAPNAAGSTAGGERRGRVRARR
                     AAVMAVPATLIAAGLAVLTAQGALGVQFAISGMPFTVTATELNGTGFEQFGALDNMAEG
                     SPNAGDTGGQVLVVTSAIKNATLTKLCQSVDLGGINLLITAGRGAEKVSATDLTTDSTV
                     LSGNAEFNNIEIGNDASTLTKAGVKGPIGVFSQQADTVRIAKLRQTNYATTAGVFKLPG
                     LKLRFSDTGC"
     gene            19652..20113
                     /locus_tag="FHS34_RS31350"
                     /old_locus_tag="FHS34_006354"
     CDS             19652..20113
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018547164.1"
                     /locus_tag="FHS34_RS31350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006354"
                     /product="DUF6114 domain-containing protein"
                     /protein_id="WP_225817679.1"
                     /transl_table=11
                     /translation="MPDRPHRGPRLAFRGWRARRPFWGGLLLTLAGGEILLTEQASLKV
                     VLHIGMQGLAGYLLPGLMVLLGLLILFNPSQRLFYSLTGVLLSLGTWLTSNLGGFFLGL
                     LLGVTGSCLAFGWLPDREPRVSRRARRKRARTAARALTPERAENMEGAA"
     gene            complement(20157..20507)
                     /locus_tag="FHS34_RS31355"
                     /old_locus_tag="FHS34_006355"
     CDS             complement(20157..20507)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129412.1"
                     /locus_tag="FHS34_RS31355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006355"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_184971697.1"
                     /transl_table=11
                     /translation="MTTVPGTGHQDPSAEVLAAAAAAFGLLAAPARLHIVWALAQGESD
                     VTGLAERTGGALPAVSQHLTKLRLAGLVRSRREGRRQVYFVDTAEQAAVVEVVRLLVGR
                     LSEGQRAPVPAR"
     gene            20679..21134
                     /locus_tag="FHS34_RS31360"
                     /old_locus_tag="FHS34_006356"
     CDS             20679..21134
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675687.1"
                     /locus_tag="FHS34_RS31360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006356"
                     /product="tellurite resistance TerB family protein"
                     /protein_id="WP_184971699.1"
                     /transl_table=11
                     /translation="MALWDRVKESASQMQTQLVAKKNDLKSGAFRDASMAMCALVAAAD
                     GSVDPSERQRVAQLIATNEVLQNFPADDLRRRFEENLNKLTADFAFGKVSVLQEVAKAK
                     KKPAEARAVVQIGIVIGGADGDFDKDEQAVVREACYALDLPPHEFDL"
     gene            complement(21235..22191)
                     /locus_tag="FHS34_RS31365"
                     /old_locus_tag="FHS34_006357"
     CDS             complement(21235..22191)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675685.1"
                     /locus_tag="FHS34_RS31365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_006357"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_184971701.1"
                     /transl_table=11
                     /translation="MTYTTHISRSIRRSRGAAVVALAAATALLAGCSSDDTNDNPLTGG
                     KASGDSVVVGSNNFPESNLLADIYGEALKAKGIEVTYKPNIGSRETTYGLIKNGSVSVM
                     PEYNGALLAHLDKNAVPKTLEETTKAVNAKLDSKLTLLKPSSAQAKDSVTLNAATAKKY
                     HLTEKSSIADLKDVAGDLVIGASPEFQTRQQGLVGLKAVYGLEFKSFKALDAGGPLTRA
                     ALKKDDVQVADIFTTDPKITEEKFVVLQDPKNLFGFQNVQPLVHKGTLSKEGVAALDAV
                     SAKLDTETLLELDTQVQAEKKDPLDVAKAWLKSAGLG"
ORIGIN
        1 cccggaacgg gagttcgccg gccatgtgcc cgtggcggac ctcttcgacc ggcagccggc
       61 ggtgctgctg gagcggctcg cggacgactg aggagacggg ccgcccaccg cccgcgccga
      121 ggcggcgggt aggcgcgggt cggtggtgcc gcgctcgtgc accgcgtgga ggccggtgcg
      181 ggcgggacag ggccgtgtgc gggcgcggcg gggaggccgc aggcgggtgc ggtggtgccg
      241 ggtccgtgca gcgcgtggag gccggtgcgg aggggacggc tccgtgtgcg ggcgcggcgg
      301 ggaggcctca ggcgggtgcg gtggtgccgg gtccgtcggt cgcgccgagg tcgtgggggg
      361 ggcggtggtg ccgtgagcgt ggacggtggg gagtccggtc cgggcgtggt ggtggcggct
      421 ctcgggggac gcggaccgca tcagcagtgt gtctgtggca cgcagtggcc cgggcggccg
      481 cggggccttg cgtccgggcg cccccgggag cctcccccgc cgactgcttg acagttcacc
      541 cgtcccgtgc gggactggga gggcgaagcc gggcggacga gtcgggggtg ggtccactgc
      601 cggagctgcg ctatcccagc gttcccgaac tggtggcctc ggcgagggca ttggccggcc
      661 gggaacccgg gctgtgcgcg ctgcgccagg tgggcgtctc gcgcgcggga agacccctgc
      721 acctgctgtc ggtgggccac gcccgccgtg cggtactggt ggtcgccggc gcccacgcca
      781 acgagccgac gggcggttcc accctgcggg cgctcgccga acgtgtgctg gtcgaccggg
      841 agttgcggac gggcacctcc tggcacttcc tgctgtgcgc ggacccggac ggcgcgagtc
      901 tgcacgtgac ccccgcgccg cgcagcctcc tcgactacca cctcggcttc taccggccga
      961 cgggcgccga gcagccggag tggtcaccgt cggtgctgcc gccggaccgg ctgccgcccg
     1021 agacccgggc gctgaccggc gtgatcgacg agttgcgccc gtacctccag gtgaccctgc
     1081 acggcaccga cctcggcggc agctgggtgc agctgaccaa agacgtgccg ggcctcgccg
     1141 agccgttcgc caagtccgcg gcggagctgc acatcccggt ggagacgggg gcctcggacg
     1201 cggcgggctg gccggcctcc ggtcccggcg tgcacgtgat gccgggcccg gagacgggcg
     1261 tggcctaccc gagcatgccg gacgacgccc ggcacagcac ctggtaccac gcgcaccggt
     1321 acggcggtct gacggccgtg gtggaggtgc cgatgtgggc cagcgacctg gtggacgacc
     1381 ccgcaccgca cccggcaccg gcggcggcca tgcggcgcct gtccgcccgg ctgctgcggg
     1441 acgcgcggga ggtggagcgg atcctcgccg aggcgctgcc ccggctggac ggcgcggacg
     1501 ggcccctgct gcgggccgcg cggtgggcac tggagctgat tccgggcctg gccgaggact
     1561 ggatccacac tgctccggcg ggcaccacga tggcgtacgt cggcagcgtg gacgccttcg
     1621 gacggcggct gccgctgcgg gccgcggcga tgctgctccg ggtgctgcgg gaggcggacg
     1681 accgggcggc accgcgcctg gaacagctcg tctccacctg gtgcgacgcg ttcgcccagc
     1741 ggttcagggc ccgctgggtg ccgttggagc accaggtgga gcaccagtcg cggacggtgc
     1801 tggtggcggc acatcaggcg cgggagcagg cgtcctgacg gggtggcgga accggcgccg
     1861 gaccggtgcg ggccgcccgg tcgtggccgc cggtcagccg tccagggcga agacgtgtcc
     1921 cgtgcgcgcg ttcatgacgc acacgctggt gtacgtctcc gtgaagtcga ccgaccggcc
     1981 gttccaccga ccgcgcgcgt gggtcgtcac cggcgcgaag atcatcggac agaagacgtc
     2041 cgcggccggg atgcggtcga tgtcaccttg cacgtccgcc agttcgccgc aggcctgggc
     2101 cgcgtgcgcg tgcccccggg gcgggtcgca caacagcagc gcgccgtggg tgacgccggt
     2161 ccgggcgtca ccccgggtga ccgtcaaata cagccagttg ccctgctggt tgtcggggga
     2221 ggccgcgcgg gccgggcccg ccgtcaggag tccggcggcg gccagcaggg cgccggccgc
     2281 cgctgccgtt ctggtgatgt gggtcatggc ccttgcatcg gcacgcgggg ccgccttccg
     2341 cagtgccgct cacccgatcg ggacggcatt cgcgcaccac cgggcatctg ttcgaaccgg
     2401 gtcggccgcg ggctcccttg ccggcaaccg gtccgcggag cgctcagctc gccgagagcc
     2461 ggaacgccat cctgccgaag gcgatctggt cgccctcgcg gacgacgacc gcgccggtca
     2521 cccggcggcc gttgacggtg gtgccgttgg tcgaacccag gtccctgagc acccacagcc
     2581 cgccctgccg gcggagttcg gcgtgcaccc gggagacggt ctcgtggttc aggcgcagcc
     2641 cgttcgcggg atcgcggcct atgcgcagcg ggtgggtgtg cgccgggtgc ggcagcagca
     2701 gcttgggcag ccgctcggcc tgccaggcgc ggcgcagccg tacggtgaac ccggagacgg
     2761 cctcgacggt gccgaggacc gcgcgggaga agcggttctc ctggggcagg tcggcgacga
     2821 gggcggccag ttcgtcggag cggcgggcgg cgagcgccag ttccatccgg cgcacgaacg
     2881 tgtcgtgcga gagccggccc agggcgacgc cgtcgcgcag cacccgcagc gccttgtcac
     2941 gctccgcgtc ggacaggcgc gcgggatagg tggagaactc gaaggacgac gtcacgcagg
     3001 tgattgtcgg gcagtgaacc ccgggtgtcc agaaaacgcg gaaccggtgc ccgtgtgcgg
     3061 gtacttccgc gacacctgcc gtcaaagggc gaattcgaag gcggattgat cgtccggagc
     3121 ggcacgatgg tggggcggga catcacggtg agcagacgaa ggggaaccgt ccgtgcagtt
     3181 cgaggtgtgg gcaccgcagg cagaacgagt gacgctccat tgcgagggcg cgacgcgcgc
     3241 gttggcgcgc gaccccgcgc gcgcggggtg gtggacgggt gaggcggagg cggagcacgg
     3301 cgcacggtac ggtttcgcgc tggacgacgg tcccgtgcgc cccgacccgc gctcgcgccg
     3361 ccagccggac ggcccggacg ggctgagcgc ggtcgtggac cacgggcgtc acgagtggcg
     3421 cgcccgctgg gcggggcgcg ggctgccggg tgcggtgctg tacgaactgc acgtgggcac
     3481 gtacacccgc gagggcaccc tggacgccgc cgcggaccgg ctggaccacc tggtggaact
     3541 gggagtgaca catgtgcagt tgatgccggt gtgccccttc ccggggcggc acggctgggg
     3601 atacgagggc gtgtcgctgt gggcggtgca cgagccgtac ggcggccccg aggcactgaa
     3661 gcgcttcgtc gaccgggcgc acggactcgg gctgggtgtc gtcctggacg tcgtgcacaa
     3721 ccacttgggg ccgtccggga accatctgcc cgcgttcgga ccgtacttca cggacacgca
     3781 ccggacgccg tggggatcgg cggtgaacct ggacgcgccg ggttcggacg aggtgcgcgc
     3841 gttcctgctc ggcagcgcgc tggcgtggct gcgggactac cggatcgacg ggctgcggct
     3901 ggacgcggtg cacgcgctgt acgacacgcg tgcgtgccac ttcctggagg agctgtcagc
     3961 ggccgtggac ggcctggccg gcgaagtggg ccggccgctg ttcctgatcg ccgagtcgga
     4021 catgaacaac ccgcggttca tcaccccgcg cgcggagcac ggcatcgggc tgcacgcgca
     4081 gtggaacgac gacttccacc acgcgctgca caccacgctg accggtgagt cccagggcta
     4141 ctacgccgac ttcgcgcggg agccgttcgc ggcgctcacc aagaccctca ccggcggcta
     4201 cttccacgac ggcacgtact ccggcttccg gggccgccgt cacggccggc cgctggaccg
     4261 cgcgcgcgtg gccgggcacc ggctgctcgg ctacagccag acccacgacc aggtcggcaa
     4321 ccgcgcccag ggcgaccggc tcgccgcgca cctctccccc ggtctgctgg cctgcgcggc
     4381 cacgctgacg ctgaccgcgc cgttcacacc gatgctgttc atgggcgagg agtgggcggc
     4441 gggcacgccc tggcagttct tcaccgacca caccgacccc gggctggccg aggcggtccg
     4501 gcagggcagg cggcgggagt tcgcggcgca cggctgggcc gaggaggagg tgccggaccc
     4561 gcaggacccg gcgacccggg agcggtcctg cctggactgg tcggagccgg aacgcgagcc
     4621 ccacgcgcgc gtgctggcct ggtaccggcg gctggtggcg ctgcgccgcg cgcagcccga
     4681 cctcaccgac ccggacctgg ccgacacgaa ggtggcctac gacgaggagg cccgctggct
     4741 ggccttccgg cgcggggacg tacgggtggc ggtgaacctc ggcaaggagc cggcggcgat
     4801 cccgctgggc accggccgcg tggaggtcct ggccgcctgg gacccggtca cggcaccggg
     4861 cgcggacgga ctgctcctgg tccccggcga gtcctgcgtg gtgctggccc agccctgacc
     4921 cgaccacccc ggcgatcccc cggaaaaccg cacccggtac cgcccgcggc ccacgaccgc
     4981 cgtccggtac cgcgtgcggc cgggagttgc ggccctgcaa ccgcccacgg acaccaggtg
     5041 cggcctggcc ccccagatat caggtgcggc cttgaagccg ccacccggcg accgcatacg
     5101 gtcctggagc cgtgggcggt gtccggggtg ccgcgcgggg gcggtgtccg ggcggcgggc
     5161 gccgcggatc cggggcggct tccgctacgg ctccgggtcg tcttccttga agtcggtcac
     5221 ccgttccagc aggatcggct cccacacgcg ccggagctgg gtgcgcagca ggggcagcgg
     5281 gccgtccgtg cggccctcca ggcggtcggt gaggcggatg acggtgtcgc agcgggcgag
     5341 ccacaggccg cgcaggcagg gacgggcgcc gtagccggcg agggtggcgg cgcggaccgc
     5401 ggccggggag ccgacggcga ccgcgagccc ggcgatgtcc tcggcggggt cgccgagggc
     5461 cgccgcggtc cagtccagga tgccccgcac ccggccgtcg tcgctgacca ccacgtgggc
     5521 gccggtcagc ccgtggtggg tgaggacggc ggtgccgggc tgcgcggcga gctgggccgc
     5581 gccgggcggg gtgagctggt gcagccgggc ggcgtcgaac tcgtcggcgg cggcgagccg
     5641 ttcggccgcg tgcacggcca tccggcgcag cgcctccagc gagcgcggcg cggtgcgcgg
     5701 cacgccgagc gtctcggcct ggcgggcggg gaccgcgcgc agcccgccga gcagcccggc
     5761 gagatcggcc tcgccgacgg cggagacgtc gtactcgtcg gccgtgccgc cgggcaccct
     5821 ggtgtcgagg gtgtaggcga gaccgggcgc ccagtcgccg tgtgcgacgc tggtcgggac
     5881 ggcgacgggc agatgcgggc ggaccaggtc gcgcagccgc agttcgcggc ggcggcgcac
     5941 ggacgcctcg cggtcgggcg ccaggcgcag cacatggcgg ccgccgatcc accaggtgtg
     6001 ctcgcggtcc tccgtcacgg gccgcacttc gggtccgccg gtgccgtcgc cgccctcctt
     6061 gagcagcgag cggaccagtc ggcggacggt gtccacggtg ggggtcggtg cctgggtcat
     6121 gggtcgagcg tcgccgttcc ggtgggtgtc gaggatgggg ctccctggtt ctctcagtcc
     6181 actatgacca tctcacgggt ggtgttgttg aggcggcgcc cgccgtcctc ggtgaccgtg
     6241 acgatgtcct cgatacgcac cccgaagcgg ccgggcagat agacgccggg ctccacggag
     6301 aagcacatgc cgggcacgag cggcagctcc tcgccctcga tcatgtacgg cggctcgtgc
     6361 gtggtgacgc cgatgccgtg cccggtgcgg tggatgaagt acgcgccgta cccggcgtcg
     6421 gtgatcaccg cgcgggcggc gcggtcgacc tcctggcagg ccacgcccgg gcgtacggcc
     6481 cggaagcctg cctcctgggc ggcgcgcacg aggtcgtgga cccggcgctc ctcctcggtc
     6541 ggctcgccga cgtggaccgt gcgcgtggtg tcggagccgt agccgtcctt cagtccgccg
     6601 aagtcgagga cgaccatgtc gccggtccgg atgacgcggt cgccgacctc gtggtggggg
     6661 ttggcgccgt tggggccgga gccgacgatg gtgaagtcga cctgggagtg gccgaagcgg
     6721 gtcagcaggc cggcgaggtc gtggccgacg tcggactcgc ggcggccggc gaagggaacc
     6781 ttgcggatcg cctcgaacgc ctggtcggcg gccgcgcccg cggctgccag gagttccacc
     6841 tcggccgcgt ccttgaccgc gcggagcatg ggcagggcgt cggtgagggc ggcgtacgac
     6901 gtctccggca gggcccgctg gaggcccagc aggtgcatgg cccaggcgtt gtcgctgatg
     6961 ccgtaccggc cgcggccgtc gaggaggcct gcggtgacgg cgtaggggtc cttgccgtcg
     7021 gtccagtcgc gcagggtcag cgcggcggcg ccggccgcgt gctcggcgtc gggggcctcc
     7081 agggcgggca cgacgagcac cgggtcgcgg cccggggcga ggaccagtac ggtcagccgt
     7141 tccgtgaccg cggtgggtgt gtagccggtg agccacacca tgtccggccc cggggccacg
     7201 agcagtccgg cgaggccggc gtcggcggcg gagcgcacgg cgcgctccat gcgggccctg
     7261 tggtcggcgg cggtgaaggg cgcgggcgtg gtaccggtca tccgggcctc cgggcgcggg
     7321 tcggcaaacg gggcgatggc gtctcgggca gcatcctgcc cgcccgggcg gagccacgcg
     7381 agccggtccc ccggacaggc gtaccgcggg ccgcggagca gggcttcggc tgggcccatg
     7441 atgacgcgtg cgacggaggg tgaccagcgg gtttcatggt gttcacgggg ccggacgccg
     7501 ggggcggctc ccgcccggtc agaccgccac ggcgggggtc accgtcaact gctggtagcc
     7561 gccctcgctg tggcgcacgg tgaggagcac cgcctctccg gggcgggccc gggtgacggc
     7621 ccggaccagg tcggccgcgg tgtcgacgcg ggccgagccg aactggagca cgacgtcccc
     7681 gcggatcagg cccgccgtgt aaccggatcc gggtacgtgc acgcccacca cgagcgcgcc
     7741 cggcttctcg gcgtcgacga cctccagacc gagggtcatg ccgtgcgggg cccggccggg
     7801 gtccggggcg gccgagggcg gggtcttggc ggcgggggcg gacggcgggg cctggcgtct
     7861 cagttcggcg agcctgctca ggccgatcac cgtggcgccg accgtgccga cgccgacgcc
     7921 cgagagcacc agcacggtgg cggtgcacag ggcgaacagc agggtccgca gccgccgccc
     7981 gcgccggcgt gcggcgtgcg ggcggcgggc ggggccgggg gtgtcgtcgt cccgtcggtc
     8041 ctgaccgggc atcggcttgg gacgcaacgc tgtctgttcc atggttcgct cgcctccggc
     8101 tggtgctcta cccggggcgg ggggccgcga cgagacacga aagggtgaga ctggccggag
     8161 ggtggcggag ggtagccatg aagggcggca cggcgcgatc ccgcccccca ccggctccct
     8221 ccggcacctc ggcacgccgc gtgcgcacgg gaggcacgcg accggccgcg gccgggcacg
     8281 gccgggaggg tcgcgtccgg ccggccgaac cactccggcg cccggccccg gtgttccggc
     8341 cggaccgcgt cggccgcgtc cgtcgcgtgc ggtgtgtcag gccctgtggc ctccgccgtg
     8401 gccgccgtgc gccgcgccgt ggtcgaactt cagggcctcg ggcggcatga cgacgaaggg
     8461 ccgcatcatg cccatgtcct cgtgctccag cagatggcag tggtacatga accggccgta
     8521 cgcgccgtcg aagcggccca tgatccgcag ctgctggctc cccggcaccc ggaagacgtc
     8581 cttgtatcgg ccgagcagct ggaagtcggc caggtggatg tgcatcgggt gctcgatggg
     8641 cgcgaggtcg aggaagctcc acggctcgtg gctgccctcg ccgatggtga agccgagccc
     8701 gtcgttgaac gtgcgcgcgg tgcgccggta cgtcttcgtg gtgccgtcgg gtccggtgat
     8761 ctggacgatg ccgtcggccg ggagccggag gccctcccgg tccgcgacct cggccatctc
     8821 ccagatctcc gcatgacccc cgccgccctt ggtggcgggc ggggtgagca ggatcagacg
     8881 gtggcgtgcg ggatgtcgtg ggtgaggcgg cggaaggacc cggagagcac ctcgggcagt
     8941 tcgaaggtgt cctcctcccc gcagccctcc ccgacacgga actccggcac ggccggatac
     9001 gccacgtcac cggccggatc gggcactccc gcgggctggt tggcgccctt gttcaccagc
     9061 cgcagggtac ggccggccag ccggcggaag tcggccagca ggtcgaagcg ctcggccggc
     9121 gcggtggtca ggacgggcaa gttccccgtc gaagtcgacc ggcaaggggc gcggcagcag
     9181 accgccgtca ctgccgccgg tcggcgacga gcagcgggat ctcccggtcc ccggagggca
     9241 gccggagggc gtcctcctcg tcgtcacgga cgaggtaggt gccgtacagg cccgtcatca
     9301 cgttccaccg ggtgatgttc atcgcgtggt cgtggtacca ccactggacc gcccggtggt
     9361 cgttcgggta ctccgacagc tgggcgtcgc cgggcccacg ccgttgtccg tccagccgtc
     9421 gttgccgccg ccggtctgcg cgccgtgcag atgggtcacc acccaggcgg gcagggcggc
     9481 gacgtccttg ttcggctcga cgccttcgcg gccgggttcg gtggtggcct gcgggcggcc
     9541 gtccgtgcgc cgcggcacct ccacggcggt gaccgggtac tcgccgtcct tcgggatgcg
     9601 gttggtccag gcgatgcgga cgcgctgtcc gcgccgtacc tcgatggtcg ggcccggcac
     9661 ctggccgtcg tagccccaca tcagggtcgg cggtaactgc gggtgcagac gcacccgggc
     9721 cgggcgcagg gctatctcgg tctcgcaccg tacgtcgccc gcggcgggcc gcagcaccgg
     9781 cggcaccgtc aacggcgcga cgtacggcat gagttcgttg ttctcgggcc tcttcgccgc
     9841 cctgtcggcc gtggtctctc cgacgagccg cccgatgatc tcggtcaagg ccgaacaccc
     9901 ccgtgtgttc cgcggtcgtt gtctctcctt ccgcaagact cacgagggct caccggcgtt
     9961 ccctgaaggc ccgattccgt acgcggagat tccgcgaccg tcagccgcgc gccaggaccg
    10021 gcacggcggg ggcccgggcc ggtacgacgg gtgccgggac cggtgcgacg ggcgggtggt
    10081 ccggcaggaa gccgtgggcg cggcggccga gccacgccgc cttgtagcgg tcggcctccc
    10141 ggtgccagtg gaggatcccg gccagccagt tctgcaggtc cagcacatag gcgcccacgg
    10201 ccgtgcgcgc gtcggcggac agtccgaagt cgtcgcagag aaccggcagt tcatgggcga
    10261 tcacgtgctg gaactgctcc atgcgctggg tcatcaggtc atggacgacg cgcagcgcgt
    10321 ccgggtagtc cacgccgaag aagttctgca cgaccaggac ggcgttgtgg atctcgccct
    10381 cgtactcgat ctccttctgg taggagaaga cgtcgttgac gaggcaggcc cagtcgatgg
    10441 cggcgttctc cagggagcgc accggaccgc tggcgtacac ctcgggcggg atcgccgggc
    10501 cgtggcccat ccggcacagg ctgagggtga ggtccgagcc gaaggtggag cgccgcatct
    10561 ccaggtagtc gaccgggtcg gggacgcggt tctgcagctg gttggagagc tcccagaccc
    10621 agctctcggt catggcgtcc acggaggcct tgagggtgcg ccgctggccg gcggtcatcc
    10681 cggccgtggt gcgggtccac aggtcgatca gtccgcgttc catggcgtcg ccggcgacga
    10741 cggccggctc accctcgacg gccatgcact ccgacagccg ggccgtggtc agccgggcgg
    10801 cggcgaggtc ccggcggtgg ccgtacacca gcgggtagta gtcgtcgccg taggtgcccc
    10861 aggcgagcca ctgggcgctg aggtcgaggg cctccgcggt ggcgtccggg tccagtcctg
    10921 cggagcacag cgcgaggtcg tacgcggcga gcttgtcctc gtcccagaca ccctcccgga
    10981 ggatgcccat gcggtggcac cagtcgagga ggcggccccg ggccccgtcg aggtgggggc
    11041 tgagacccag ctcgtacggc atgtgcagat cggggatgcg ggacggtccg accttctggt
    11101 ggggcacgtg ggagtaggcg cgcagccggt cccgggcggc cgcggcgagg agcgcgccga
    11161 catcggcggc ggaggtgccg gggccgctcg gcgactgcca gggcgagccg gaccgggcgc
    11221 cctggttcat gtagcggctg gagcgcaggt gccactcgtg gccgccggac tgccagtcct
    11281 gcagaccctt ggtgtaggcg gcgacggcgg cggcctcgcc gggtgtgagg cccttctcca
    11341 gggctacggc ggggacttcg gtgagcgcgg tgtgctcgaa ctggtggagc cgggaggtga
    11401 ggacgtcgtt gacggtgtcg gcggcctcct gggtggtgca gccgaagaac ttctccagga
    11461 ccagcacgcc gttgctgttc tcgccctcgt cctcgacctc gcgctggtag gagaacaggt
    11521 cgttgcgcag gtggacggcg tcggcgaacg tctccatgag gacgcgcagc ggccgggtgc
    11581 cggcgacgga cgcgggcacc tcggcggtcg cgtactccac gagcccggcc gaccaggggg
    11641 cgccgcccac cttgcggcgc atctcgatgt attcgacggg gttggcgatc cgcccctcgt
    11701 ggatgttgga cagctcccac atcgactcgt tgagcaggtg ctcggtggcg acggagaacc
    11761 ggcggcgcca gtccaccgac atcgacggca ccgtgcgctc ccacaggtcc ttcaggcccg
    11821 cctcgacggg gttctccggc tcgggcacgg cggtcgacgg gtcgagcggc atgaacagcg
    11881 gcagacggtc caggtgcgcc tttccggcgg cgcggtcggg ggtgcgcttg aacatgtcga
    11941 ggaagtggtc gtcgaagaag aacacccata cgtaccagtc ggtgatcagc gagagagcgg
    12001 ggccgtcgca gtcggggtgg gtgtaggagc acaggagccc gtagtcgtgc gcctccaggt
    12061 cggcctgctc ccagatcccg gagccctcca gcatgcccat ctcgcgggcc caccgggtgg
    12121 agtgggcccg ggcctcgtcc aggtgcgggt tgaggcgcgc gggatacggc atgtagaagt
    12181 gcgggagttc gaacggctgc gtcatggccc gggctctacc cgcggctccg gacccgcatc
    12241 cgcccggcgg cacatgatca caccatcgcg tgaaccgccc ccgaaacgtg gatccgtggt
    12301 ggtgacttgt ggcgtcggcg cccttgccgt gcccgcgcgc gcgggccacg gtaggcggca
    12361 tgacctcctt cgtgctgccc catgaggtgc acggcgacgg cgcccacaag gtgttcgccg
    12421 tgcacggctg gttcgccgac cggtccgcct tcgcggccgt cctgccggac ctcgaccgca
    12481 cctccttcag ctatgcgctg gtcgacctgc gcggatacgg cgaggcccgg gacgccacgg
    12541 gctcgtacac gacggccgag gcggccgtgg acctggtgga gctggcggac cggctcggct
    12601 gggcgcggtt ctcggtgatc gggcactcga tgggcggcgc ggtggcccag cggctgctca
    12661 ccgtggcccc gcaccggctg cgccggatcg ccggcgtctc gcccgtgccc gcgtcgggca
    12721 tgccgttggc cggcgagcag gcggtgctgt tcgcggacgc ggcgcaccgg gcggagaacc
    12781 ggcgcacgat catcgacttc accaccgggg gccgccggcc cgccgcctgg ctggaccgga
    12841 tggtcgaccg ctcgctggag cgcagcgacg ccaaggcgtt ccgggcctgg ctggactcct
    12901 gggcggggga cgacttcagc accgacgtcg agggcagcga ggtgccggcg ctcgccgtgg
    12961 ccggcgagct cgacccggcg ctgtcgccgg aggtcatgcg gcagacctgg atgtcctggt
    13021 acccgcgggc ccggctcgcc gtactgcccg gcgccggcca ctacgcgatg gacgagaccc
    13081 cgctggagct ggtccgtacc gtcgaggact tcctgcgggc ggacgacgcg gacgggacgg
    13141 acgccgcccc gggggcggcc cggggcgagc cggcgtgagc gtgcgcgagg cgccgccggt
    13201 gccggacgtc ttcgatccgc gccggtacgc cgccggggtg ccgtacgacg actaccgcgt
    13261 gctgcgcgac caccatccgg tggcctggca ggaggagccc gaggtgctgg gctggccggc
    13321 cgggcccggg ttctgggcgg tgacccggca cgtggacgtc gtgcgggtgc tgaaggacgc
    13381 cggaacgtac tcctcgtacg ccggtgcgac ccagatccgt gaccccgatc cggaggacct
    13441 gccgttcatc cgccggatga tgctcaatca ggaccccccg ggccacggcc gtctgcgccg
    13501 gctggtgagc cgtgccttca cgccgggccg tgtcgagcgc ttcgcggccg tcgcccggga
    13561 gcgggcgcgg gcgctgctcg cgggcgccct ggcgcaggcg cgggagggcg acggcacggt
    13621 cgatctggtg tccgccgtca ccgacgagta cgccctgctg aacctggcgg acctgctggg
    13681 cgtcccggag agcgaccggc ggctgctgct gcgctggacc cagcgggtca tcggctacca
    13741 ggacccggac gaggcggggc cgccggtgcg ggacggggcg ggcaggccgg tcgatccgcg
    13801 gtctccggcg atgctgcggg acatgttcga ctacgccggg cagctggccg cgttcaagcg
    13861 ccggtgtccc gccgacgaca tcatgacgtc cctcggccac gaggcggaac tcgccggtgc
    13921 cgagctggag atgttcttct tcctgctgac ggtggcgggc aacgacaccg tgcgcggcgc
    13981 ggccccgggc ggcctgctgg cgctggcgga gcatccggag gcgtacgaga cgctccgcgc
    14041 caaaaaggcc gggctcgcgt ccgcggggga cgagctgctg cgctggcatc cgccggtgct
    14101 gacgttccgc cggacggccg tgcgggacac cgagctggcg ggccggcgga tccgggcggg
    14161 tgacaaggtg gtggtgttcc acgcctcggc caaccgggac gagcgcgtct tcgccgcgcc
    14221 ggagcggctc gacctcaccc gctcccccaa tccgcacgtc tcgttcggcg acggcccgca
    14281 cgtctgtctg ggcacccact tcgcacggct gcaactgcgg ctgctgcacg aggaggtgct
    14341 gcgtgtcctg ccggagccgc cgcgcctcgc cggaccggcc ggacggctgg tgtcgaactt
    14401 catcaacggc gtcaagtcac tccgggtgca cctggcctga cgggtcggcc tggatcaggg
    14461 cgtgcgtgcc gctggtccgc cagctctgtt ccccggccgc caccagcgcg gcctcggtgg
    14521 ccgcggacag gccggtgatc acgtcggact tgagggtgcg cagcgcggcg accggtccgg
    14581 ggaagtacgc ggtcgtccgg cggaagggcg tggtcggcgg ccaccgccgg tcgcccacca
    14641 ggcggcggta gttgaggtcg cccttgacga tggtcagggt ggccgccgcg aactcggcgc
    14701 gcaggtcgtc gggcatgtcg gcgtacggca gcggggcgca ggagaacggg tgcgcgcgga
    14761 cggcgagccg gccgtcggcc atggccgacc agagcacgcg cgcgtgctcg gcggccgcgc
    14821 cgccggccgt gcgcagccgg cgcagagcgt cgaccacgtc ggcggtggtg gcgtcggaga
    14881 cgtagtacgg gtacggcttg acgtgcagga cggcccgcgc ggtccggccg ccggcgagga
    14941 ggtgggcgat cagcagcagg tcggggacga gttcacggcc cgcgttgtcg gcgacgagca
    15001 cgagcgtgcc cgtctcgtcg ggcggcagca gcgaccacag gacgtcgctg tcgtcggcga
    15061 ccagcccggg ggacgcctcc cgggcctcgg cgcccgcggc ggagagccgg aagccgagat
    15121 cggcgcggtt gccccacagc gagccgtgca gcagggcctt cgcccgctcc tgctccggca
    15181 ggtcgcgcag gccgtccagg gcggccagtt cctcgtcggt ctcgggggcg tcgagttcgg
    15241 cgcgcttgaa ggggcggaac gggtcgacgc cctgccaggg gcccgggccg aaccagccga
    15301 cggcgtcgag cagccggcgg tagaagtagc tctccgacca cagccagggt gcgtcgaacc
    15361 aggggcgccc ggtgtggccg gccaggcccc agccgtgcca ccggtcacgg tccggggcgt
    15421 cggcgggaag cggctcgatc gtcccttcgg tgcagctcct cagcagctcg tccagcgccc
    15481 ggtgctgccc ggggccgtac gggaaggcgt cccgcacctg cccgatgatc gcggggtgcc
    15541 gctcggccag cacactgtgc gggaacgagc cgggttcgtt gccgaggatc acgggtgcga
    15601 acggggtgtc gggcatgccc gtcaccgtat cgcgggcgtc aggcggtgcg gacctcccgc
    15661 tccagctgcg tggcgagggt gacgtagcgg gggcgccggt gcaccgggac gaggccccgg
    15721 atcacgaggt gccacatctc ggcgacccgg cgcggcagcc gtccgaccgg ttcgagcgag
    15781 cggccggcga cccgggtgcc gatgaagaag cacacgaggg agtgggcgac gacgccgacg
    15841 tccacatcgc cgtgcagatc ggcttctctg acggctccgg tgaacttgcg ggtggcgaag
    15901 tcgagccact cggtgaacgg atgccgcagc ggcggccgta cggcgatgtc cgcggtggcg
    15961 aggcggagtc cggcacgcgg cacgggatcc tccacggcga gccgggcgat cccgaacgtg
    16021 gtccgcatca gggcctccag ggaggagccg ccgcggctct cggcgtcggc cacgacccgt
    16081 tgcgcggctc tggactggag ctgcaggatg gcgtgggcca ggtcctcctt ggcggcgaag
    16141 tggaagtaca gggcgccctt ggtgaccttc gcgtgtgcga cgatgtcgct caggctggtg
    16201 gactcgtagc cgcgttggtc gaacaggtcg gcggcggccg tgatgatcgt ggcgcgggtc
    16261 tgttcagcgc gtaactgcct cgccatcccg ggacccctct cctcccacct caaaagaaca
    16321 ggacatgcgg tttgttttaa ccccccgcat acgataactc acccagcggc aacgggagtc
    16381 cagcgcgtca cccgcgcgga ggacagacgt gccggcggca cgccgatgac cggccgggca
    16441 caggcggccg gcacgacgag cgagatcacg tcggcttccc ccttcgtcac cggccgacgc
    16501 ccggcggcca ggaggcgacc ggcgccgcac ccatgatcga cacgatacga ggcgggcggg
    16561 cggctcctca acggggcgtg ggaacaggcg caaaacggca gaaccggtcg gtgccttcgc
    16621 gcccctccgg tgacgggcgc gccggaccgg ctgaacaggg ggcaccccgg cgccgtactg
    16681 gacgccgcag accctgttcc cgcgcctgcc gaggagacgt tccggatgac tcggatgacc
    16741 gcccgactga gcgtcagggc taccgccgcc gcggcgccgc tcctgcttct gccgtgggcg
    16801 gcggggcccg cccaggcgca cggagccccc acggacccgg tcagccgggt ctacgcctgc
    16861 tcacccgagg ggggcgcggc cggctcggcg gcctgccggg cggcgatcgc ggcgaacggc
    16921 gccccgttca ccgcctggga caacctgcgc gtggcggggg tggggggccg tgaccggcag
    16981 atgatcgagg acggcaggct gtgcagcggg aacctgccgg cgtaccgggg cctggacctt
    17041 gcccggcggg actggccggc gacgcggctg gcaccgggcg gccggctgac gctggcctat
    17101 gcgtcgacca tcgcgcacac gggcacgttc cggttgtacc tgaccaagca gggatacgac
    17161 ccgtccaggc cgctgacctg gtccgacctg ccggagcggc ccttcgccga gatcacggac
    17221 ccgccgctgc gcgacggggc gtaccgcatg agcgcgacgc tgcccgcgga ccggacgggg
    17281 cgtcaggtgc tgtacacgat atggcagaac agcagtacgc cggacacgta ctactcctgt
    17341 tccgacgtgg tcttccccag gcacgggaaa gccgccggcg tgacgcggtc caggcggccc
    17401 gcggcgacac cggcggcgcc ggcggcggcc agcccgcggc ccgcgcggac ggccggttcg
    17461 ccggtggaga gcccggcttc cgggccggag cggggtgacg ggcggcccga gcgcgccgcc
    17521 gcggccgcga ccccggtggc ccgggccacg cacggcggct cgggcccctc ggtgtcactg
    17581 ctggcgggcg gcgccaccgc ggtgctgctg ctcaccgggg gcgccgccct ggcgctgcgg
    17641 ctgcgacgac gctgaacccg aggctccggt cgctcagttg acgtagacgc ggacgcccgc
    17701 gtcggtgacg ggtgcgtact tggccgtgaa gtagccgttg gcgaagcaca gcgacgagcc
    17761 ggacgtcttg gtgaagcgct ggttggtgaa ggtgatgctg ctgtcggcgt tgtccgcctt
    17821 gccggacaga gcgggcgcct ggtacacgca ggtcacggtg cccagcaggg tgcgcagctg
    17881 gaccgtggcc tggatggcgg agccgctcgg gggcgagacg gtgaggtcgc cgccggaggt
    17941 gatcgtcgcc gagtagggca ggttgttgat ggtgatgccg ttgaccccga ggacgccggt
    18001 gacgttgctg gtgcaggtgc tgctgttgaa ggtgtgcgcg gtgacggact cggtggccgt
    18061 gccgggcgcg gtcgggttgc cggtgaccgt ggcggtgaac tgggagcccg tgcacttgac
    18121 gccgctggtg ccggtcgcgc tggagtagaa cgtcgcggaa gtgcccgagg ccaggggcgc
    18181 ggtgagggtg tcgccgacgg ccacggcggt gccgccggtg ctgccggtgg tgaggaccgt
    18241 gccggccgcg gaggccgggg tggcccaggc cagggcgagc gcggtggcgg cgccgccgag
    18301 ggcgaggagg gagcgcgtac gcatgcggat gcctctcttc cgaagtgggg ggacagatga
    18361 ggtgaggtgg ggggtggcgg tggtgcgtgc gatgccgccg gcgcggggcc gtagcgcctt
    18421 ctccgtacac cacggccccg cgtcggcggc acaccgggca ccggccggag atctcggggg
    18481 aagacctccg gccgggccgg gacaagaggg cggccgggca cggcggaaga aggaaagagc
    18541 gatcgcgccg gagccgcgct gagaggtgga gcgcttgccg ttgcagggcc gggaacgtga
    18601 ccgttgccgc gccgcgggac gcggctggtg ccgcctgccg gatccggcgc cacggatccg
    18661 tggaaacgag gcaagttgta gacctgatga agcgtcaacg tcaaggcagt caagcggagt
    18721 tgtggcgtgc ggtcgctacc cgcgcacatc ccacaccctt tttccacatc tcccttgacc
    18781 ctcgaatgta accggcggta acttcctcgg aggctactgc cgcgtaacga gaaagccctt
    18841 gcatccgccg ggaggcgcga ggaggcgtgc gcggtatccg ctgtccgcgc caggacaccg
    18901 cgccactgaa gcccaacccg cattgatcca tgcccatggg agcagacatg gcctcgtccc
    18961 cggacgtccc gtccgtcggc aacaccccgg agaatcctgg aagcgacacc ccgcccgaag
    19021 ccccgaacgc cgcggggagc accgccggcg gcgagagacg agggcgggtc cgggcccgcc
    19081 gggccgcggt gatggcggtg cccgccaccc tgatcgccgc cggtctcgcg gtcctcaccg
    19141 cgcaaggagc actgggtgtg cagttcgcca tctccggcat gccgttcacg gtcaccgcga
    19201 ccgagctgaa cggcaccgga ttcgagcagt tcggcgcgct cgacaacatg gcggagggca
    19261 gcccgaacgc cggggacacc ggcgggcagg tgctcgtcgt cacctccgcc atcaagaacg
    19321 ccaccctcac caagctgtgc cagagcgtcg acctcggcgg catcaacctg ctgatcaccg
    19381 cgggcagggg cgcggagaag gtctccgcga ccgatctgac caccgactcc accgtgctgt
    19441 cgggcaacgc ggagttcaac aacatcgaga tcggcaacga cgccagcacc ctgaccaagg
    19501 cgggcgtgaa gggtccgatc ggggtcttca gccagcaggc ggacaccgtg cgcatcgcca
    19561 agctgcggca gaccaactac gccacgacgg caggtgtgtt caagctgccc ggcctcaagc
    19621 tccgcttcag cgacacgggt tgctgagcac cgtgccggat cgcccacacc ggggaccgag
    19681 gctcgccttc cgcggatggc gggcccgccg gccgttctgg ggcgggctgc tgctcaccct
    19741 cgccggcggc gagatcctgc tcaccgagca ggcctcgctg aaggtcgtgc tgcacatcgg
    19801 catgcagggc ctggccggct atctgctgcc gggcctcatg gtgctgctgg gtctgctgat
    19861 cctcttcaat ccgtcccagc ggctcttcta ctccctcacc ggtgtcctgc tctccctggg
    19921 cacctggctc acctccaacc tgggcggctt cttcctcggc ctgctcctcg gcgtcaccgg
    19981 cagctgcctc gccttcggct ggctcccgga ccgggaaccg cgtgtcagcc gccgcgcacg
    20041 ccgcaagcgg gcgaggaccg cggcacgcgc cctgacaccg gaacgggcgg agaacatgga
    20101 gggagcggcc tgacggcacc gcccccgaga ggggcgaggg acacacccga cctgattcag
    20161 cgggccggta cgggggcccg ttgcccttcg gacagccggc cgacgaggag gcgtacgacc
    20221 tcgaccacgg cggcctgttc ggcggtgtcg acgaagtaca cctgacggcg gccctcgcgg
    20281 cgcgagcgga cgagtccggc gagtctgagc ttggtcaggt gctggctgac ggcgggcagc
    20341 gcaccgccgg tccgctcggc gagcccggtc acgtcgctct caccctgggc gagcgcccac
    20401 acgatgtgca gccgggccgg cgcggcgagc agtccgaacg cggcggccgc cgcggcgagt
    20461 acctcggcgg aggggtcctg gtggccggtg ccgggcactg tcgtcactgt cgccttcctc
    20521 ccgccgcgtg gtccccgtgt tccgtccgtc cctgccgtgg tatgcggact cagtgtagat
    20581 ctcaggaact ttccgtccgc cccactagtt tctacggtgc tgtagaagtc gctgccgggt
    20641 gccgagggcg caccggacgg ccgatacgag gagtggacat ggccctgtgg gaccgcgtca
    20701 aggagtccgc gtcgcagatg cagacccagt tggtggcgaa gaaaaacgac ctgaagagcg
    20761 gcgcgttccg cgatgcgagc atggcgatgt gcgcgctggt ggccgccgcc gacggttcgg
    20821 tggatccgtc ggagcggcag cgggtggccc agctcatcgc caccaacgag gtgctgcaga
    20881 acttcccggc ggacgacctg cgccggcgtt tcgaggagaa cctgaacaag ctgacggccg
    20941 acttcgcctt cggcaaggtg agcgtgctgc aggaagtcgc caaggcgaag aagaagccgg
    21001 ccgaggcgcg ggccgtcgtc cagatcggca tcgtcatcgg cggcgcggac ggtgacttcg
    21061 acaaggacga gcaggccgtg gtccgtgagg cgtgctacgc gctggacctg ccgccgcacg
    21121 agttcgacct ctgagctttc cgggaagcgg cgggcacgga gcgggacgcg ggtgacccct
    21181 gggtccgggg tcacccgcgc cggcacgccc gtggccgttc cgggcggtgg tccgtcagcc
    21241 gagaccggcg gacttcagcc aggccttggc gacgtccagc gggtccttct tctccgcctg
    21301 cacctgggtg tccagctcca gcagggtctc ggtgtcgagc ttggcggaga ccgcgtcgag
    21361 cgcggcgacg ccctccttgg acaacgtgcc cttgtggacg agcggctgga cgttctggaa
    21421 gccgaagagg ttcttcgggt cctgcaggac gacgaacttc tcctcggtga tcttcgggtc
    21481 cgtggtgaag atgtccgcga cctggacgtc gtccttcttc agcgccgccc gggtgagcgg
    21541 gccgcccgcg tccagcgcct tgaaggactt gaactccagg ccgtagacgg ccttcaggcc
    21601 caccaggccc tgctgccggg tctggaactc cggcgaggcg ccgatgacca ggtccccggc
    21661 gacgtccttc aggtcggcga tggaggactt ctcggtgagg tggtacttct tcgcggtcgc
    21721 cgcgttgagc gtgaccgagt ccttggcctg tgccgaggac ggcttcagca gcgtgagctt
    21781 cgagtccagc ttggcgttga cggccttcgt ggtctcctcg agggtcttcg gaacggcgtt
    21841 cttgtcgagg tgtgccagga gcgcgccgtt gtactcgggc atcaccgaga cggagccgtt
    21901 cttgatcagc ccgtaggtgg tctcgcggct gccgatgttc ggcttgtagg tgacctcgat
    21961 ccccttggcc ttgagggcct caccgtagat gtcggcgagc aggttgctct cggggaagtt
    22021 gttggacccg acgaccacgc tgtcgccgct cgccttgccg cccgtgaggg ggttgtcgtt
    22081 cgtgtcgtcg gaggaacagc ccgccagcag agccgtcgcc gccgcgaggg cgaccaccgc
    22141 cgcgcctcgg ctcctccgga tggacctgct gatgtgggtc gtataagtca cccgacgatc
    22201 caatc
//
