LOCUS       NZ_JACHJK010000006     20471 bp    DNA     linear   CON 29-SEP-2024
DEFINITION  Streptomyces echinatus strain CECT 3313 Ga0436950_06, whole genome
            shotgun sequence.
ACCESSION   NZ_JACHJK010000006
VERSION     NZ_JACHJK010000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces echinatus
  ORGANISM  Streptomyces echinatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 546324)
  AUTHORS   Whitman,W.
  TITLE     Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the
            genomes of soil and plant-associated and newly described type
            strains
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 546324)
  AUTHORS   Whitman,W., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2020) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 160.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014203595.1-RS_2024_09_29
            Annotation Date                   :: 09/29/2024 05:39:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,466
            CDSs (total)                      :: 8,381
            Genes (coding)                    :: 8,094
            CDSs (with protein)               :: 8,094
            Genes (RNA)                       :: 85
            rRNAs                             :: 7, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 5, 1 (5S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 287
            CDSs (without protein)            :: 287
            Pseudo Genes (ambiguous residues) :: 0 of 287
            Pseudo Genes (frameshifted)       :: 116 of 287
            Pseudo Genes (incomplete)         :: 236 of 287
            Pseudo Genes (internal stop)      :: 12 of 287
            Pseudo Genes (multiple problems)  :: 77 of 287
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:56:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 244967
            Orig. end                         :: >265438
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JACHJK010000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..>20471
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..>20471
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..>20471
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:>10471](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..>10471
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            177..1463
                     /locus_tag="FHS34_RS18695"
                     /old_locus_tag="FHS34_003791"
     CDS             177..1463
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669158.1"
                     /locus_tag="FHS34_RS18695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_003791"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_184967209.1"
                     /transl_table=11
                     /translation="MPMSRRALAAAVVALVLPLSACGSGGDDGGTTDASGKVEGDITFQ
                     TWNLRANFKSYFEDLIAGFEHKYPGTHVKWVDQPAEGYADKLGADAAGGTLPDVVNVSP
                     DLVAPLARAGLVLDLDKAAAKYRPEYLDAAWSSHRVPGMNGTYAFPWYLNTGPLFYNKA
                     LFTKAGLDPDQPPRTYDELFTDALRMAEKSDGKVATLANVPTIEDFGRYGVPLMNEQGT
                     GFAFNDPKGVELLTKYKALYDAKALDPQALTATGESSGKKFLTGAVAMNPGSALDLGNF
                     KKNAPGLYRNIGITDQITSTGHVNMYVMGVMVNSRTRHTPAAVAFAHFVTDARNQMSFA
                     KKVAIFPSTAGSLDDPYFTKEDGTDETRVRIAAAKSLKNAVNYTPVLFSEQMKTALRNE
                     VAKALQGKESPQEALDNAVKAADRLLQQG"
     gene            1469..2356
                     /locus_tag="FHS34_RS18700"
                     /old_locus_tag="FHS34_003792"
     CDS             1469..2356
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386364.1"
                     /locus_tag="FHS34_RS18700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_003792"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_184966747.1"
                     /transl_table=11
                     /translation="MAAPLRIKRQLPFGPWLFAAPGLLVTGAFVLYPFGSTLANSFTDR
                     RTLVPGHFVGLANFRELLHDEMFWTGLRNSVLYILGVVPALVVLPLLLALLVRKNIPGI
                     TFFRSVFYTPVVASIVVVGLIWVWLLDERGLVNSLLESVGIGRIGFLSDQWLLLLSAMA
                     VTVWKGLGYYMIIYMAALANVPRELHEAAAVDGAGPVRRFLSVTVPAVRSTMVLVAALS
                     SVAAFKVFSEVYLMAGPSGGPAGEDTTLVMLVQRTGTGLTGRVGYACALSVVVFAVTVV
                     LMLLVLRADRREES"
     gene            2353..3261
                     /locus_tag="FHS34_RS18705"
                     /old_locus_tag="FHS34_003793"
     CDS             2353..3261
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003977910.1"
                     /locus_tag="FHS34_RS18705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_003793"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_184966749.1"
                     /transl_table=11
                     /translation="MSVLEKVRPGRPATAVAREPRVTDEHGRRVRAGELVWRYLLLLAV
                     LALTVGPFLWQLSTSLKGPTEDIYGSPPRFLPGHPTLHNYARVADTIPVWDYALNSLKV
                     AAANVVTNCAGSALAGYALARLRYRGRRVTTLVFVLAMLVPVEGIVIAQFTTMRELGLN
                     NTLIGVVLPGAIGAMNVLLMRNAFRNLPYEIEEAAYVDGANVWQRFLRVALPSVKGTLA
                     VVAIFAFMGAWDDFLWPLIVLSDPSKFTLTIGLNYLHGTFANDERLVAAGTVIAVAPLI
                     ALFACLQRYFFRGVGEGAVKG"
     gene            3300..4556
                     /locus_tag="FHS34_RS18710"
                     /old_locus_tag="FHS34_003794"
     CDS             3300..4556
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656230.1"
                     /locus_tag="FHS34_RS18710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_003794"
                     /product="glycosyl hydrolase"
                     /protein_id="WP_184966750.1"
                     /transl_table=11
                     /translation="MPPAVRFGVNYTPSERWFHHWLDFDLDSVRADLDSIAALGLDHIR
                     VFPLWPYFQPNRTLIRPRAVDQLVALADAAAERGLDVNVDGLQGHLSSFDFLPAWTRTW
                     HRRNLFTDPDVTDGQAAYLRTLAAALADRPGFIGMTVGNEVNQFAAGPHPDPDRVTAAE
                     AGRWLTRMLTACAEGAPGRLHLHASYDAAWYQDDQPFTPAHSARLGAVTAVHSWVFNGT
                     AQRHGRTSVPTEHHAAYLVELSKAWADDPHRPVWLQEVGAPAPLVPAEHAAAFAEATIT
                     NVLDCPDLWGVTWWCSHDVSRTLGDFPALEYSLGLLTDERRPKRIARVLAEAARRTHPA
                     PAVRGTALAVPADPAHRSRCAPGGDVFEAFFRLVADGARPTTVLDTRADDKDHLAARGI
                     TDVVTPGQVLPTPQGGTRS"
     gene            4553..6586
                     /locus_tag="FHS34_RS18715"
                     /old_locus_tag="FHS34_003795"
     CDS             4553..6586
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676398.1"
                     /locus_tag="FHS34_RS18715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_003795"
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="WP_184966752.1"
                     /transl_table=11
                     /translation="MNPTRRTVLIAATATAGAALAPSPLATAAPRAAAATPPHASYWYP
                     DTLPAGAPGPGITWRSLKSWRAADDPDLDCNAASVPLAARFTPTPANATARSGQARIQA
                     LVSFGPTSGNPSQGSATADHYALTHWAYLDELVFWGGSAGEGLILAPNAPVVDAAHRHG
                     VPVLGNVFLPPAAYGGQLQWTRDLVQRDAAGHYPLAAQLVAVAAAYGFDGWFLNAETGG
                     GNTALGTAVLGFVQELRALAAARGQRVTWYDAMTVNGTVSWQGALNSQNQAFFRAADDM
                     FVDFRWSAGTLASSGTKADGLGRSRYQLWAGVDVESNGSGTYVDWDAIVPAGKPHITSV
                     GLYRPEWTRNHLPADQRAPEYFHAADDRFWTGRSLDPARPDASDPWRAPAVSVADRSTV
                     TSVPFASVFNTGHGLRWYEEGAVTSDAPWNHLGLQDRLPSRRWVVRTAGKRPTVTFDFA
                     DAWRGGSSVLVAGEPDQPVVVDLYQTRLPIGVNTVVELTYRSESGEVNVESAVATAEPS
                     TAGETPPYRYLAVNSVNAVKTVNGWQTVTVPLTGLSGTVHALGVRLTATEGPVRWRLGG
                     LAVRADGTPPAPAAPSGARVTAANGGDLRLAWNPAPGTVRHHTLHRLLPDGTRRFLGAT
                     AQRAYFLSGLRPEQGEKAARFEVRAVGELYNASTPVTVTHPW"
     gene            6616..9636
                     /locus_tag="FHS34_RS18720"
                     /old_locus_tag="FHS34_003796"
     CDS             6616..9636
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669154.1"
                     /locus_tag="FHS34_RS18720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_003796"
                     /product="glycoside hydrolase family 38 C-terminal
                     domain-containing protein"
                     /protein_id="WP_184966754.1"
                     /transl_table=11
                     /translation="MHDDRTLVEARLRRVLDERVRPAVYPESVPLRVAVWHAPGEPVPV
                     AEGLAAVTEPIEVGARWGAPWGTSWFRVTGTVPEAWAGKTVEALLDLGFDENMPGFQCE
                     GLVYRPDGTPVKGLNPRNQWVRVGAPVTGGEEVRLHIEAASNPVILDYHPFRPTSLGDR
                     DTAGQEPQYTLTRMDLAVFDETVWQLVLDLEVLGELMAELPVDSARRHDILRAVERALD
                     AVDLQDVNGTAGRARERLTGVLSAPAVPSAHRISAVGHAHIDSAWLWPLRETVRKVART
                     TSNMTALIEDEPEFVFAMSQAQQWAWVKEHRPEVWARVKKAVADGRFVPAGGMWVESDT
                     NMPGSEAMARQFVHGKRFFLDEFGIENEEAWLPDTFGFAAGLPQIIKAAGSKWLLTQKI
                     SWSQTNRFPHHTFHWEGIDGTRIFTHFPPVDTYNCSMKGSEIAHAVRNFRDKGRARHSL
                     APTGWGDGGGGTTREMVAKAARLRDLEGSATVTWDTPRAFFEKAEAEYPAPPVWVGELY
                     LELHRATLTSQAKTKQGNRRSEHLLREAELWAATAAVRAGFAYPCAELDRIWKTVLLHQ
                     FHDILPGSSIAWVHREARATYERLAAELTRIIEGAQRALAGEGTTPLVFNAAPHPCHGV
                     PAGGAGTPAAAGRTTLGAREDGGFTLDNGLLRITVDARGLVVSAYDPAADRETVAPGEA
                     ANLLQLHPDFPNMWDAWDVDSFYRNTVTDLTGAESVTAGEDGASVRIVRSFGDSRVTQL
                     LSLPPGERRLLIDTEVDWHETEKFLKLAFPLDLHAERYASETQFGHVHRPTHTNTSWEA
                     AKFEACNHRFVHLEEPGWGVAVVNDSTYGHDVTRTVRDAGDRGTTTTVRVSLLRAPRFP
                     DPETDQGVHRFRHALVPGASVGDAVREGWRINLPERSATGAHEVAPLVTVDDDAVVVTA
                     VKLADDGSGDVVVRFHEAHGGRARATLTAGFEVADVTVTDLLERPVTGEQPPAREGERI
                     TLRLRPFELMTLRLRRP"
     gene            10001..>10471
                     /locus_tag="FHS34_RS42625"
                     /pseudo=""
     CDS             10001..>10471
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="FHS34_RS42625"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="terpene synthase family protein"
                     /pseudo=""
                     /sec_met_domain="T1TS (E-value: 3.5e-24, bitscore: 80.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAWLPRATGDRLDPAVDAVVVATFLDDQFDGPLADQPLRVAAAC
                     RAFTDVIASAGAVPAGAGPLTAAFAQVWIRLAHRASPAWLESAGQHWRWYVNAYVEEAG
                     NRAHRHTPSRVEHFALRRRSGFVYAMLDLSQKAYGFELPPRLGRDPTVRRMPD"
     gene            complement(10675..12108)
                     /locus_tag="FHS34_RS18730"
                     /old_locus_tag="FHS34_003799"
     CDS             complement(10675..12108)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009327133.1"
                     /locus_tag="FHS34_RS18730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_003799"
                     /product="lipase maturation factor family protein"
                     /protein_id="WP_184966758.1"
                     /transl_table=11
                     /translation="MDWFTSPGDWLSRLVFQRALAAVYLVAFLTAALQFRALLGERGML
                     PVPRFTARVRFRRAPSLFQLHYSDRFFAACAWAGCGVSAALLAGADSALPLWAGILLWL
                     VPWALYLSIVNVGQTWYAFGWESLLLETGFLGAFLGNDEVAPPVVVLFLLRWILFRVEF
                     GAGLIKLRGDACWRKLTCLYYHHETQPMPGPLSWFFHHLPKPLHRAEVAANHVTQLVVP
                     VLLFTPQPIASAAAALMIVTQLWLVLSGNFSWLNWITIVLALSALRLPTTAPPVPPAPL
                     WYEVLVLAVAALLVFLSYHPVVNMISRRQVMNRSFDPLHLVNTYGAFGSVSQVRYEVVV
                     EGTLDAAPREDSEWREYAFRGKPGDPRHWPRQFAPYHLRLDWLMWFAALSPGYAGEWFG
                     GLVERLLENDRDTLRLLRRSPFPPDTPPRFVRARLFRYRYTSWRELRETGACWERTYVR
                     EYLPPTRLAGAVSGTSGDR"
     gene            12236..13468
                     /locus_tag="FHS34_RS18735"
                     /old_locus_tag="FHS34_003800"
     CDS             12236..13468
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676409.1"
                     /locus_tag="FHS34_RS18735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_003800"
                     /product="DUF6777 domain-containing protein"
                     /protein_id="WP_184966760.1"
                     /transl_table=11
                     /translation="MRIPTGTIVCVLAVLFAAGCAGSGVKQTRLGEMVLLQAATDRGPE
                     PFTASTAISSTATAAPRSASPRSTVPVSAAELAAPLRATRTLSGGTPGLYRGSPHVAGC
                     DAERHIGYLAADEARADAFARAAGVTRSALPRYLRGLTPVVLGTDTRVTNHSYRDRRAQ
                     GYQAVLQAGTAVLVDDRGVPRVRCACGNPLGPPAPTRGGAGARGTPWAGYRPNKVIVVA
                     PAPRAVKSITIVDSETRTWTERRVGQDVSRDHVVPPPVRDVSPSPPTTAATPSPADGRP
                     SPRDSRPATAPAGTGPSPAGTAAPDGRTDAPSGAAGLADGNPVAPTQEPRAPAPSPARS
                     SPSPPRPRPSPAASSPSPSRPSPSPDPSDRIAPLTMPETADLPDGAGPVPGLPDGAGAA
                     PDGVTASRTGG"
     gene            13564..15648
                     /locus_tag="FHS34_RS18740"
                     /old_locus_tag="FHS34_003801"
     CDS             13564..15648
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996056.1"
                     /locus_tag="FHS34_RS18740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_003801"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_184966762.1"
                     /transl_table=11
                     /translation="MADRGASALSLPEDWPAHPDPILALNRMGSFDWDLDAGLMDMDAQ
                     AFEVFDLLPEEYDGHPESLTVRVPPPEAARLDAAVARAIKDGSENYGAYFRIRRRDGTL
                     RWTHTQGYIRRDESGRPSRVVGIVRDATEELADSAARSLRAAQDEAFRQQTGVVQVISA
                     ALAHARSVQDVIDVLKDTHGIRHLGAASLVMGLVEAGRIRLVAEGPVGSFVPGTRITRI
                     DEPYPMSEVVRTLSPRFIESAEEFEADYPILWPHITDLRITAAAYLPLIAQARPIGAMG
                     LLYDDRRGFSDEERAVLVALGSSIGQSLMRAMLYEQEKDLAQGLQQAMLPRTIPSVRGA
                     DIAVRYRSAALGRDIGGDWYDLIPLPGGTASGGGRVGAVIGDVQGHDTHAAAVMGQLRI
                     VLRAYAAEGHPPATVMARASVFLHELDTDRFATCLYAEADLSTGVVQVVRAGHIDPLIR
                     RGDGSCDRIPVQGGLPLGLSAEFGRLEYPVTTLELDPGHTLLLCTDGLVELPGTDLDDG
                     MSGLAALIREGPDEVRDLADRLIQVAEERGGDDDVALLLLRRRTRQTTRPGGRLQQHVA
                     PGDPEALTQARHMIRAAVRAWGAGGQADEIELVADELVTNALLHTEGSAIVTLRALDGT
                     GHRLRIEVEDCSSALPRRRDAGENGVSGRGLLLVDRLADSWGVEARGGGKAVWCEFRLP
                     "
     misc_feature    13584..13594
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            15707..16570
                     /locus_tag="FHS34_RS18745"
                     /old_locus_tag="FHS34_003802"
     CDS             15707..16570
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006377630.1"
                     /locus_tag="FHS34_RS18745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_003802"
                     /product="Fpg/Nei family DNA glycosylase"
                     /protein_id="WP_184966764.1"
                     /transl_table=11
                     /translation="MPELPEVQALTDFLTEHLVGLRVVRVLPVAVSVLKTYDPPVTAVE
                     GAEVTAVRRHGKFLDIETDGGLHLVTHLARAGWLQWKDRLPDGPPKPGKGPLALRVALE
                     TGEGFDLTEAGTQKRLAVYVVRDPAEVPGVARLGPDPLAGDFDEDRLAALLKAERRQLK
                     GALRDQSLIAGVGNAYSDEILHAAKMSPFKLAASLTPEETHRLYEALRGTLTEAVERSR
                     GVAAGRLKAEKKSGLRVHGRTGEPCPVCGDTIREVSFADSSLQYCPTCQTGGKPLADRR
                     LSRLLK"
     gene            complement(16608..17261)
                     /locus_tag="FHS34_RS18750"
                     /old_locus_tag="FHS34_003803"
     CDS             complement(16608..17261)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676412.1"
                     /locus_tag="FHS34_RS18750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_003803"
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="WP_184966766.1"
                     /transl_table=11
                     /translation="MRSLERHRDVGAYALGVLDEAEAFRFEDHLMECSRCAAQVTEFGP
                     TSRQLLLYRRATPRFVHPMAQPGPRLLDRLLGELAQRHRARRRRLLYGLAASVVLAVAG
                     PAIVAFAGHAGPAPRVTAATDPHTGVWARVTSEDEDWGSDLRLEVKDGSGRHTCRLVAV
                     GLDGTEQDVAGWTNAGDGSRPTTAMGSTALHPDQIQRYEVRTDDGKRLVVLEAR"
     misc_feature    complement(17399..17413)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.5"
                     /tool="antismash"
     gene            complement(17413..17928)
                     /locus_tag="FHS34_RS18755"
                     /old_locus_tag="FHS34_003804"
     CDS             complement(17413..17928)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484373.1"
                     /locus_tag="FHS34_RS18755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_003804"
                     /product="hypothetical protein"
                     /protein_id="WP_184966768.1"
                     /transl_table=11
                     /translation="MRHRGHESTDGTDGHELAVPMAWLYAEYIADELLRTGDLMPPTSF
                     EFRAGRDALALTVFLSDTDGELSGIRVISQLENWLALTAYDQPWQDWVRARMAELTEGA
                     AVSGAPCPDLALAEDAWRWLEETELLAPDLDAVPGGGAVFGEDEGPKVWTPAWRLGLPL
                     GHLAIHLF"
     gene            complement(18081..18629)
                     /locus_tag="FHS34_RS18760"
                     /old_locus_tag="FHS34_003805"
     CDS             complement(18081..18629)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019068325.1"
                     /locus_tag="FHS34_RS18760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_003805"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_184966769.1"
                     /transl_table=11
                     /translation="MTAGTSLTIGTTTAGHELAALQREHGGPLFALLLRLCDGDRQRAE
                     DLVQETLVRAWQHPEALHADDFDSVRPWLLTVARRLAIDARRARQARPPEVGDEVPENA
                     RVTADHAERAAAMLDVREAVKTLTPEHRDVLILVYFRGASVAEAAQALGIPPGTVKSRA
                     YYALRALRRVLPGYAADLR"
     gene            18846..19997
                     /locus_tag="FHS34_RS18765"
                     /old_locus_tag="FHS34_003806"
     CDS             18846..19997
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116926.1"
                     /locus_tag="FHS34_RS18765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHS34_003806"
                     /product="CapA family protein"
                     /protein_id="WP_184966771.1"
                     /transl_table=11
                     /translation="MIGRRQQVALALTAVLAAGAACQNQNQESGTRGQPAPAATSGGGF
                     TLVASGDVLPHTSVIERAAYDADRNGHDFRPMLSGVQPVVSRADLALCHMDTVYGADGD
                     YTGYPVFKSPPQIAEALAATGYDSCSTASAHALDDGTAGIGRTLDAMDRAGLRHAGTAR
                     SENEARSVRFLRAGRAKVAHLSYTFGTNYPMPPGQPWAVNLMDAERMIADARAARRGGA
                     DVVVVSVDWGTEWQEEPDRIQLTLAQQLTASATDGRPDIDLILGTHAHVPQAYEKVNGT
                     WVVYGLGDQIAGEMYNREGAQDPRGNESSLGRFTFVPPARPGGPWRVTRAEFLPQLYDL
                     DAGRVVDLNRAIAQGADLEAVRDRIGKAVLSRGAAQDGLVMGE"
     misc_feature    complement(20438..20452)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 gtcaagaccc taaagcgcat tagcagttga cggcaagttc tcggccaaag tcgcctgacc
       61 tgcactaatt aaggccggat ttctttagct cgaacgaatg cattgacttt ctccgaacgc
      121 gctgggcaag gtcttcggcg ccaccgacag cccgacccag caagggagcc gtgtccgtgc
      181 ccatgtcccg cagagccctc gccgccgccg tcgtcgccct cgtcctgccg ctgagcgcct
      241 gcggctcggg cggtgacgac ggcggcacga ccgacgcctc cggcaaggtg gagggcgaca
      301 tcaccttcca gacctggaac ctgcgcgcca acttcaagtc ctacttcgag gacctgatcg
      361 ccggcttcga gcacaagtac cccggcacgc acgtgaagtg ggtggaccag cccgccgagg
      421 gctacgccga caagctcggc gcggacgccg ccggcggcac cctgcccgac gtcgtcaacg
      481 tctccccgga cctggtcgcc ccgctcgcca gggccggcct cgtcctcgac ctcgacaagg
      541 ccgccgccaa gtaccgcccc gaatacctgg acgccgcctg gtccagtcac cgggtgccgg
      601 gcatgaacgg cacgtacgcc ttcccctggt acctgaacac cggcccgctc ttctacaaca
      661 aggccctgtt caccaaggcc ggcctcgacc ccgaccagcc gccgaggacg tacgacgaac
      721 tcttcaccga cgccctgcgg atggcggaga agagcgacgg caaggtcgcc accctcgcca
      781 acgtgcccac catcgaggac ttcggccgct acggcgtccc gctcatgaac gagcagggca
      841 ccggcttcgc cttcaacgac cccaagggag tcgaactcct caccaagtac aaggcgctgt
      901 acgacgccaa ggcgctcgat ccgcaggcgc tgaccgccac cggggagtcc tccggcaaga
      961 agttcctcac cggcgccgtc gccatgaacc ccggcagcgc cctggacctc ggcaacttca
     1021 agaagaacgc gcccggcctc taccggaaca tcggcatcac cgaccagatc accagcaccg
     1081 ggcacgtcaa catgtacgtg atgggcgtga tggtcaactc ccgcaccagg cacaccccgg
     1141 ccgcggtcgc cttcgcgcac ttcgtcaccg acgcgcggaa ccagatgtcc ttcgccaaga
     1201 aggtcgccat cttcccgagc accgccggct ccctggacga cccgtacttc accaaggagg
     1261 acggcaccga cgagacccgg gtgcggatcg ccgccgcgaa gtcgctgaag aacgccgtca
     1321 actacacgcc cgtgctgttc agcgagcaga tgaagaccgc actgcgcaac gaggtcgcca
     1381 aggcgctcca gggcaaggag agcccccagg aagccctcga caacgctgtc aaggccgccg
     1441 accggctgct ccagcagggc tgaccgccat ggccgcaccc ctgcgcatca agcgccagct
     1501 ccccttcggg ccgtggctgt tcgccgcacc cggactcctc gtcaccggcg ccttcgtgct
     1561 ctaccccttc ggctccaccc tggcgaactc cttcaccgac cgccgcaccc tggtccccgg
     1621 ccacttcgtg ggcctcgcca acttccgcga gctgctccac gacgagatgt tctggaccgg
     1681 actgcgcaac agcgtcctgt acatcctggg cgtcgtcccg gcgctggtcg tactgccgct
     1741 gctgctcgcc ctgctggtgc ggaagaacat ccccgggatc accttcttcc gctccgtctt
     1801 ctacaccccg gtcgtcgcct ccatcgtcgt ggtcggcctg atctgggtgt ggctgctgga
     1861 cgagcgcggc ctggtcaact cgctgctgga gagcgtgggg atcggccgga tcgggttcct
     1921 cagcgaccag tggctgctgc tgctcagcgc catggcggtc acggtgtgga agggcctcgg
     1981 ctactacatg atcatctata tggcggcgct cgcgaacgtg ccgcgcgaac tgcacgaggc
     2041 cgcggccgtg gacggcgccg gaccggtgcg ccgcttcctg tcggtcaccg tgcccgccgt
     2101 acggtccacg atggtgctgg tcgccgcgct ctcctcggtc gccgccttca aggtgttctc
     2161 cgaggtgtac ctgatggcgg gcccgagcgg cggcccggcc ggcgaggaca ccaccctcgt
     2221 catgctcgtg cagcgcaccg gcaccggcct gaccggccgg gtcggctacg cctgtgccct
     2281 ctccgtcgtc gtcttcgccg tcaccgtggt cctgatgctg ctggtgctgc gcgccgaccg
     2341 cagggaggag tcgtgagcgt cctggagaag gtgcggcccg ggcggccggc caccgccgtc
     2401 gcccgggagc cgcgcgtcac cgacgagcac ggccgccgcg tccgggccgg cgaactggtc
     2461 tggcggtatc tgctgctgct cgccgtcctc gccctgaccg tcggcccgtt cctctggcag
     2521 ctgtccacct ccctcaaggg acccaccgag gacatctacg gctcaccgcc caggttcctg
     2581 cccggccacc ccaccctgca caactacgcc cgggtcgccg acaccatccc ggtctgggac
     2641 tacgccctga actccctgaa ggtcgccgcc gccaacgtcg tcaccaactg cgccggttcg
     2701 gccctcgccg ggtacgccct ggcccggctg cgctaccgcg gccggcgtgt caccacgctc
     2761 gtcttcgtgc tggccatgct cgtccccgtc gagggcatcg tcatcgccca gttcaccacc
     2821 atgcgcgaac tgggcctgaa caacaccctg atcggagtgg tcctgcccgg cgcgatcggc
     2881 gccatgaacg tgctgctgat gcgcaacgcc ttccgcaacc tgccctacga gatcgaggag
     2941 gcggcctacg tcgacggcgc caacgtctgg cagcggttcc tgcgcgtcgc cctgccctcg
     3001 gtcaagggca ccctggccgt cgtcgcgatc ttcgccttca tgggcgcctg ggacgacttc
     3061 ctgtggccgc tgatcgtgct cagcgatccg tcgaagttca ccctgaccat cggcctcaac
     3121 tatctgcacg gcaccttcgc caacgacgaa cgcctcgtcg ccgcgggcac cgtgatcgcc
     3181 gtggccccgc tcatcgccct gttcgcctgc ctccagcggt acttcttccg cggggtcggc
     3241 gagggagccg tcaagggctg accgacgtca accgcttccc gaggacagca aggacatcca
     3301 tgcctcctgc cgtgcgcttc ggcgtcaact acacgcccag cgagaggtgg ttccaccact
     3361 ggctcgactt cgacctcgac tccgtgcgtg ccgacctcga ctcgatcgcc gcgctcggcc
     3421 tcgaccacat ccgggtcttc ccgctgtggc cgtacttcca gcccaaccgc accctgatcc
     3481 ggccccgtgc cgtcgaccag ctcgtggccc tcgccgacgc ggccgccgaa cgcggcctgg
     3541 acgtcaacgt ggacggcctg cagggccacc tgagcagctt cgacttcctt cccgcctgga
     3601 cccgcacctg gcaccgccgc aacctcttca ccgacccgga cgtgaccgac ggacaggccg
     3661 cctacctgcg cactctcgcc gccgccctgg ccgaccggcc gggtttcatc ggcatgaccg
     3721 tcggcaacga ggtcaaccag ttcgccgccg gaccccaccc cgaccccgac cgcgtcacgg
     3781 ccgcggaggc ggggcgctgg ctcacccgga tgctcaccgc ctgcgccgag ggcgcccccg
     3841 gccggctcca cctgcacgcc tcctacgacg ccgcctggta ccaggacgac cagcccttca
     3901 cccccgccca ctccgcccgg ctcggcgccg tcaccgccgt gcactcctgg gtgttcaacg
     3961 gcaccgccca gcgccacggc cgcacctccg tgcccaccga acaccacgcc gcctacctgg
     4021 tcgagctgag caaggcctgg gccgacgacc cgcaccggcc ggtgtggctc caggaggtcg
     4081 gcgcccccgc gcccctggta cccgccgagc acgccgccgc cttcgccgag gccacgatca
     4141 cgaacgtcct ggactgcccg gacctgtggg gcgtcacctg gtggtgctcc cacgacgtct
     4201 cgcgcaccct cggcgacttc cccgcactcg agtactccct cggcctgctg accgacgagc
     4261 gccggcccaa gagaatcgcc cgcgtgctgg ccgaggcggc ccgtcgcacc caccccgccc
     4321 cggcggtacg cggcacggcc ctcgccgtgc ccgccgaccc ggcccaccgc tcccgctgcg
     4381 cgcccggcgg cgacgtcttc gaggcgttct tccggctcgt cgccgacggg gcccgcccga
     4441 ccaccgtgct cgacacgcgc gccgacgaca aggaccacct cgccgcgcgc ggcatcaccg
     4501 acgtcgtcac tcccggccag gtactcccca ccccccaagg aggcacccgc tcgtgaaccc
     4561 caccagacgc accgtcctga tcgccgccac cgccacggcc ggggccgccc tggccccctc
     4621 gccgctcgcg acggccgccc cgcgggccgc cgccgcgacc ccgccccacg cctcgtactg
     4681 gtacccggac acgctgcccg ccggcgcccc cggcccgggc atcacctggc gcagcctgaa
     4741 gagctggcgc gcggccgacg accccgacct cgactgcaac gccgcctccg tgccgctcgc
     4801 cgcccggttc accccgaccc cggcgaacgc caccgcccgc tccggacagg cccgaatcca
     4861 ggcgctggtc tcgttcgggc cgacgtcggg caacccctcc cagggctcgg ccaccgccga
     4921 ccactacgcc ctcacccact gggcctacct cgacgagctg gtgttctggg gaggctcggc
     4981 cggcgagggc ctgatcctcg cgccgaacgc gcccgtcgtg gacgcggccc accggcacgg
     5041 cgtccccgtc ctcgggaacg tcttcctgcc cccggcggcc tacggagggc agctccagtg
     5101 gacccgggac ctggtgcaga gggacgccgc cgggcactac ccgctggccg cgcaactcgt
     5161 cgccgtggcg gccgcgtacg gcttcgacgg ctggttcctg aacgcagaga cgggcggcgg
     5221 gaacaccgcg ctcggcacgg ccgtgctggg cttcgtccag gagctgaggg cgctcgcggc
     5281 ggcccggggg cagcgggtga cctggtacga cgcgatgacc gtgaacggca cggtgagctg
     5341 gcagggcgcc ctgaacagcc agaaccaggc cttcttccgg gcggccgacg acatgttcgt
     5401 ggacttccgg tggagtgcgg gcacgctcgc ctcgtccggc acgaaggcgg acgggctggg
     5461 gcgcagccgg taccagctgt gggccggcgt cgacgtcgag tcgaacggtt ccggcacgta
     5521 tgtggactgg gacgccatcg tgccggccgg caagccgcac atcacctccg tcggcctcta
     5581 ccggcccgag tggacccgca accacctgcc cgccgaccag cgggctcccg agtacttcca
     5641 cgcggccgac gaccggttct ggaccgggcg gtcactcgat ccggcgcggc ccgacgcgag
     5701 cgatccctgg cgggcgccgg cggtgtccgt ggcggaccgg tcgacggtga cctcggtgcc
     5761 gttcgcgagc gtcttcaaca cgggacacgg actgcggtgg tacgaggagg gggccgtcac
     5821 ctcggacgcg ccctggaacc acctcgggct ccaggaccgg ctgccgtcgc ggcggtgggt
     5881 ggtccggacg gcggggaagc ggccgacggt caccttcgac ttcgcggacg cctggcgggg
     5941 cgggagcagt gtgctggtgg cgggtgaacc ggatcagccc gtggtggtgg atctgtacca
     6001 gacccgcctg ccgatcggtg tgaacacggt tgtcgagctg acgtaccgga gcgagtctgg
     6061 ggaggtgaac gtcgagtcgg cggtggcgac ggccgaaccg agtacggcgg gggagacgcc
     6121 gccgtacagg tatctggctg tgaactcggt caacgctgtg aagaccgtca acggctggca
     6181 gaccgtgacg gtcccgctca ccggcctgtc cggcaccgtg cacgccctcg gcgtccggct
     6241 caccgccacc gagggcccgg tgcgctggcg gctgggcggc ctcgcggtcc gcgccgacgg
     6301 caccccgccc gcgcccgccg ccccctccgg cgcccgcgtc accgcggcga acggcggcga
     6361 cctccgcctc gcctggaacc ccgcccccgg caccgtccgc caccacaccc tccaccgcct
     6421 cctccccgac ggcacccgcc gcttcctcgg cgccaccgcc cagcgcgcct acttcctctc
     6481 cgggctgcgg cccgaacagg gcgagaaggc cgcacggttc gaagtacgcg ccgtggggga
     6541 gctctacaac gcctcgaccc ccgtgaccgt cacccacccc tggtaatcac ccggaatcca
     6601 cagggagcac cccgcatgca tgacgaccgc acgctggtgg aagcccgcct caggcgcgtc
     6661 ctcgacgaac gtgtccgccc cgccgtgtac cccgagtcgg tgccgctccg ggtcgcggtg
     6721 tggcacgcgc ccggcgaacc cgtaccggtc gcggagggac tcgccgccgt gaccgagccg
     6781 atcgaggtgg gcgcccggtg gggtgctccc tggggcacca gctggttccg ggtgaccgga
     6841 accgtgcccg aggcatgggc cgggaagacc gtcgaggccc tcctggacct cggcttcgac
     6901 gagaacatgc cgggcttcca gtgcgagggc ctggtctacc ggcccgacgg cacgccggtg
     6961 aagggcctca acccgcgcaa ccagtgggtg cgcgtcggcg cgcccgtcac gggcggcgag
     7021 gaggtgcgcc tgcacatcga ggccgcctcc aacccggtca tcctcgacta ccaccccttc
     7081 cgccccacct cgctcggcga cagggacacc gccgggcagg agccgcagta cacgctcacc
     7141 cgcatggacc tcgccgtctt cgacgagacc gtgtggcagc tggtgctgga cctggaggtg
     7201 ctcggcgagc tgatggccga gctgcccgtg gactccgccc gacggcacga catcctgcgc
     7261 gccgtcgagc gggccctgga cgccgtcgac ctccaggacg tgaacggcac cgcgggccgg
     7321 gcccgggagc ggctcaccgg cgtgctgtcg gcccccgccg tgccgtccgc gcaccggatc
     7381 agcgccgtcg ggcacgcgca catcgactcg gcgtggctgt ggccgctgcg cgagaccgtg
     7441 cgcaaggtgg cccgtacgac gtccaacatg accgcgctga tcgaggacga gccggagttc
     7501 gtgttcgcca tgtcccaggc gcagcagtgg gcctgggtga aggagcaccg gcccgaggtg
     7561 tgggcgcggg tgaagaaggc cgtggcggac gggcggttcg tgccggccgg cggaatgtgg
     7621 gtggagtcgg acaccaacat gcccggctcg gaggcgatgg cccgccagtt cgtgcacggg
     7681 aagcggttct tcctcgacga gttcggcatc gagaacgagg aggcgtggct gccggacacc
     7741 ttcgggttcg ccgcgggcct cccgcagatc atcaaggcgg ccggctccaa gtggctgctg
     7801 acgcagaaga tctcctggtc ccagacgaac aggttcccgc accacacctt ccactgggag
     7861 ggcatcgacg gcacccggat cttcacgcac ttcccgcccg tcgacaccta caactgctcc
     7921 atgaagggca gcgagatcgc ccacgcggtc cgcaacttca gggacaaggg cagggcccgg
     7981 cactcgctcg cgcccaccgg ctggggcgac gggggcggcg gcacgacccg ggagatggtg
     8041 gccaaggccg cccggctgcg cgacctggag ggctcggcca ccgtcacctg ggacaccccg
     8101 cgggcgttct tcgagaaggc cgaggccgaa taccccgcac cgccggtctg ggtgggcgag
     8161 ctgtacctcg aactgcaccg tgccaccctc accagccagg cgaagaccaa gcagggcaac
     8221 cggcgcagcg aacacctgct gcgcgaggcc gaactgtggg cggccaccgc ggccgtccgc
     8281 gccggatttg cctacccctg cgcggagttg gaccggatct ggaagacggt gctgctgcac
     8341 cagttccacg acatcctgcc cggctcgtcc atcgcctggg tgcaccggga ggcccgggcg
     8401 acgtacgagc gcctggccgc cgagctgacc cgcatcatcg agggcgccca gcgggctctc
     8461 gcgggcgagg gcaccacacc gctggtgttc aacgcggccc cgcacccttg ccacggtgtc
     8521 ccggcgggcg gtgccggcac cccggccgcg gccggccgca ccacgctcgg ggcccgtgag
     8581 gacggcgggt tcaccctgga caacggcctg ctgcggatca ccgtcgacgc ccggggcctg
     8641 gtcgtgtccg cctacgaccc ggccgccgac cgcgagaccg tcgcccccgg cgaggccgcg
     8701 aacctcctcc agctccaccc ggacttcccg aacatgtggg acgcctggga cgtcgactcg
     8761 ttctaccgca acaccgtcac cgacctcacc ggcgccgagt cggtcacggc cggcgaggac
     8821 ggcgcgtcgg tgcggatcgt ccgttccttc ggtgactccc gggtcaccca gctgctgtcg
     8881 ttgccgcccg gggagcggcg gctgctcatc gacaccgagg tcgactggca cgagacggag
     8941 aagttcctga agctggcctt cccgctcgac ctgcacgccg aacggtacgc gtccgagacc
     9001 cagttcgggc acgtgcaccg ccccacgcac accaacacct cttgggaggc ggccaagttc
     9061 gaggcgtgca accaccggtt cgtgcacctg gaggagcccg gctggggtgt ggccgtcgtc
     9121 aacgactcga cgtacggcca cgatgtgacc cgcacggtgc gggacgccgg tgaccgcggt
     9181 acgaccacga cggtccgggt gtcgctgctg cgcgcgccgc gcttccccga cccggagacc
     9241 gaccagggcg tccaccgctt ccggcacgcc ctggtccccg gcgcgtcggt gggcgacgcg
     9301 gtccgcgagg gctggcggat caacctgccg gaacggtccg cgaccggagc gcacgaggtc
     9361 gccccgctgg tcacggtgga cgacgacgcg gtggtggtga cggcggtgaa gctcgccgac
     9421 gacggcagcg gggacgtggt cgtccgcttc cacgaggccc acggcggccg ggcccgggcc
     9481 accctgacgg ccgggttcga ggtcgcggac gtcacggtga cggacctgct ggagcggccg
     9541 gtcaccgggg agcagccgcc cgcgcgcgaa ggcgaacgga tcaccctgcg tctgcggccg
     9601 ttcgagctca tgacactccg gctccgcagg ccctgacccg gccccgccgc ccggcttccg
     9661 gacgaacgac cggccactcg ggtcccccga gcgactacgt gcacgtggcc tccggcggca
     9721 acggctgctt gtcgccaaag cgccgccggg ccgcctgagc cagcggcacg ccgggaagac
     9781 tcccctcgcg cagtcgcggc cgcccggcgg tgcccgggcg gccgcgggag aggcgggggt
     9841 catgccgcag gacaccgtgt tcgagcttcc cttcgcaccg gacgtcagcc cggacgcgga
     9901 cggcgcccgg cggcgcagtc ccgactggtg ccgcggcctc ggcctggtga cccaccccgt
     9961 cgaccagcag cgcttcctgc gctgggacat cgccgggctg atggcggcat ggctcccccg
    10021 ggccacgggg gaccggctgg atccggcggt ggacgcggtc gtcgtggcca ccttcctgga
    10081 cgatcagttc gacggccccc tggccgacca gccgctccgg gtcgcggcgg cctgccgggc
    10141 cttcaccgac gtgatcgcct cggccggcgc cgtgccggcc ggcgcgggac cgctgaccgc
    10201 cgcgttcgcg caggtgtgga tccggctggc ccaccgggcc tcgcccgcct ggctggagag
    10261 cgccgggcag cactggcggt ggtacgtgaa cgcctatgtc gaggaggccg gcaaccgtgc
    10321 ccaccggcac accccgagcc gggtcgagca cttcgcgctg cgccgcaggt ccggcttcgt
    10381 gtacgccatg ctggatctga gccagaaggc gtacggcttc gaactcccgc cccgtctcgg
    10441 cagggacccc acggtgcgcc gcatgcccga catcaccgcc gacgtggagg acaccctggt
    10501 gcgcggagtt cgtcaccctg gaacacgccc tcacggaccg cgtgcccccg tccgacagca
    10561 cggtcgtcgc gctgctcacc gactgcatgc gcagcgcgat gagcggctac ctgcgctgga
    10621 gccgggtctg tctgcgctac tcgcacctgg tgcccccggg cgagcccgct ctcgtcaccg
    10681 atctcctgac gtcccgctga ccgcgcccgc cagccgtgtc ggcggcagat actcccgcac
    10741 gtacgtccgt tcccagcacg cccccgtctc gcgcagctcc cgccagctgg tgtaccggta
    10801 ccggaacagc cgggcccgga cgaagcgggg cggcgtgtcc ggcgggaagg gcgagcggcg
    10861 cagcagccgc agggtgtccc ggtcgttctc cagcagccgt tccaccaggc cgccgaacca
    10921 ctccccggcg tagccgggcg acagcgccgc gaaccacatc agccagtcca ggcgcaggtg
    10981 gtagggagcg aactggcgcg gccagtgccg gggatcgccg ggcttgcccc ggaaggcgta
    11041 ctcccgccac tccgagtcct cgcgcggggc ggcgtccagc gtgccctcga ccaccacctc
    11101 gtagcgcacc tggctgacgc tgccgaacgc gccgtaggtg ttcaccaggt gcagcgggtc
    11161 gaaggagcgg ttcatcacct ggcggcggga gatcatgttc accaccgggt ggtagctcag
    11221 gaagaccagc agcgcggcca ccgcgagcac cagcacctcg taccacagcg gcgcgggcgg
    11281 caccggcggc gccgtcgtgg gcagccggag cgcggacagg gccagcacga tggtgatcca
    11341 gttcagccag gagaagttgc cggagagcac cagccacagc tgggtgacga tcatcagggc
    11401 ggcggcggcc gaggcgatcg gctgcggggt gaacagcagg accggcacga ccagctgggt
    11461 gacgtggttg gcggccacct ccgcccggtg cagcggcttc ggcaggtggt ggaagaacca
    11521 gctcagcggg cccggcatcg gctgggtctc gtggtggtag tacaggcagg tcagcttccg
    11581 ccagcaggcg tcgccgcgca gcttgatcag cccggcgccg aactcgaccc ggaacaggat
    11641 ccagcgcagc aggaacagca cgacgaccgg cggcgccacc tcgtcgttgc cgaggaacgc
    11701 gcccaggaag ccggtctcca gcagcagcga ctcccagccg aacgcgtacc acgtctggcc
    11761 cacgttgacg atcgacaggt acagcgccca cggcaccagc cacagcagga tcccggccca
    11821 cagcggcagc gcggagtccg ccccggccag cagggccgcc gacaccccgc agcccgccca
    11881 ggcgcaggcc gcgaagaaac ggtcggagta gtgcagctgg aacaggctcg gggcgcgccg
    11941 gaaccgcacc cgggccgtga agcgggggac gggcagcatc ccgcgctcgc ccagcagggc
    12001 ccggaactgg agcgccgccg tcaggaaggc gaccaggtac acggcggcca gggcccgctg
    12061 gaagaccagc cggctcagcc agtcgccggg tgaggtgaac cagtccacgg ctgtgcacgc
    12121 cctcctgtgc ggctccaccg gcgccgctgt cgtcacggcg ttccccgagt tgccagccga
    12181 tccggtgcga tgccaacaat agggcgtaat cacccaaagt gatgtggagt gtgcggtgcg
    12241 gatacccacc ggaaccatcg tctgcgtgct ggcggtgctc ttcgccgccg gctgcgcggg
    12301 ctccggcgtc aagcagaccc ggctgggcga gatggtcctc ctgcaggccg ccaccgaccg
    12361 gggcccggag ccgttcaccg cctccacggc catctcctcc acggccaccg ccgccccccg
    12421 ttccgcgtcc ccccgcagca ccgtcccggt ctcggccgcc gagctggcgg cgcccctgcg
    12481 cgcgacccgc accctgtccg gcgggacacc cggcctgtac cggggcagcc cgcacgtcgc
    12541 cggctgcgac gccgagcggc acatcggcta tctcgcggcg gacgaggcca gggccgacgc
    12601 cttcgcccgc gcggccggcg tcacccgttc ggcgctcccg cgctatctgc ggggcctgac
    12661 cccggtcgta ctgggcaccg acacgcgcgt caccaaccac tcctaccgcg accgccgggc
    12721 gcagggctac caggccgtgc tgcaggccgg cacggccgtc ctcgtcgacg accggggtgt
    12781 gccccgggtg cgctgcgcct gcgggaaccc gctcggtccg cccgcgccga cccgcggcgg
    12841 ggccggtgcc cgcggtaccc cctgggccgg ttaccggccg aacaaggtga tcgtggtggc
    12901 tccggcgccg cgggccgtca agagcatcac gatcgtcgac agcgagaccc gtacctggac
    12961 cgagcgccgg gtcggacagg acgtcagccg ggaccacgtc gtgcccccgc ccgtgcggga
    13021 cgtcagcccg tccccgccca ccacggcggc caccccgtca ccggccgacg ggcggcccag
    13081 cccgcgcgac agccgcccgg ccaccgcccc ggccggcacc ggaccgtccc cggccggcac
    13141 cgcggcaccg gacggccgta ccgacgcccc gtccggcgcg gccggcctcg cggacgggaa
    13201 ccccgtggcg ccgacgcaag agccacgcgc ccccgctccc tcgccggccc ggtccagtcc
    13261 ctccccgccc cggcccaggc cgtccccggc cgcgtccagc ccctcaccgt cccggcccag
    13321 cccgtccccg gacccgtccg accggatcgc cccgctcacc atgccggaga ccgcggacct
    13381 ccccgacgga gccggtccgg tcccgggcct ccccgacggc gccggtgcgg ccccggacgg
    13441 tgtgaccgcc tcccggaccg gcggctgagc gtgcgccggg ggccgcgcgg aacgccgggc
    13501 gggccggcgc cggtgcccgc cgaccaggtc gaagaatcca cccgatactg gcaaggtggc
    13561 cccatggccg atcggggcgc gagtgccctg tcactcccgg aggactggcc cgcacacccg
    13621 gacccgatcc tcgcgctcaa ccgcatgggc agcttcgact gggacctgga cgccggtctg
    13681 atggacatgg acgcccaggc cttcgaggtg ttcgatctgc tgcccgagga gtacgacggg
    13741 cacccggaat ccctgaccgt acgcgtcccg ccgccggagg ccgcccggct cgacgcggcg
    13801 gtcgcccggg cgatcaagga cggcagcgag aactacggcg cgtacttccg catccgccgc
    13861 cgcgacggca ccctgcgctg gacccacacc cagggctaca tccggcgcga cgagtcgggc
    13921 cgcccgagcc gggtcgtcgg catcgtccgc gacgccaccg aggaactcgc cgacagcgcg
    13981 gcccgcagcc tccgggccgc ccaggacgag gcgttccgcc agcagaccgg cgtcgtgcag
    14041 gtcatctccg cggccctcgc gcacgcccgc agcgtccagg acgtcatcga cgtcctcaag
    14101 gacacccacg gcatccgtca tctgggcgcg gccagcctgg tgatgggcct ggtggaggcg
    14161 ggccggatcc ggctggtggc cgagggcccc gtgggcagct tcgtccccgg cacccggatc
    14221 acccggatcg acgagccgta ccccatgagc gaggtcgtcc gcacgctcag cccccggttc
    14281 atcgaatccg cggaggagtt cgaggcggac tacccgatcc tctggccgca catcaccgac
    14341 ctgcggatca ccgcggccgc ctatctgccg ctgatcgccc aggcccgccc gatcggcgcg
    14401 atgggcctgc tctacgacga ccggcgcggc ttctccgacg aggagcgcgc cgtcctggtc
    14461 gcgctcggca gcagcatcgg gcagagcctc atgcgggcca tgctctacga acaggagaag
    14521 gacctcgccc agggcctcca gcaggccatg ctgccgcgca ccatccccag cgtccgcggc
    14581 gccgacatcg cggtccgcta ccgctcggcc gccctgggcc gggacatcgg cggcgactgg
    14641 tacgacctga tcccgctgcc cggcggcacc gcctccgggg gaggccgggt cggcgcggtc
    14701 atcggggacg tccagggcca cgacacgcac gcggcggccg tcatgggcca gctgcggatc
    14761 gtgctgcgcg cctacgccgc cgagggccac ccgccggcca ccgtgatggc ccgcgcctcc
    14821 gtcttcctcc atgaactcga caccgaccgg ttcgccacct gcctgtacgc ggaggccgac
    14881 ctgtccaccg gggtcgtcca ggtggtgcgc gccgggcaca tcgacccgct gatccggcgc
    14941 ggcgacggca gctgtgaccg gatccccgtc cagggcgggc tgccgctcgg cctgtccgcc
    15001 gagttcggcc ggctggagta cccggtgacc accctcgaac tcgaccccgg ccacaccctg
    15061 ctgctgtgca ccgacgggct ggtcgagctg cccggcaccg atctggacga cggcatgagc
    15121 ggcctcgccg cgctcatccg cgaggggccg gacgaggtgc gcgacctcgc cgaccggctg
    15181 atccaggtgg ccgaggagcg gggcggtgac gacgacgtgg ccctgctcct gctgcgccgc
    15241 cgcacccggc agaccacgcg tcccggcggc cggctccagc agcatgtggc gcccggcgac
    15301 ccggaggccc tcacccaggc ccggcacatg atccgcgccg cggtccgcgc ctggggggcc
    15361 ggtggtcagg ccgacgagat cgagctggtc gccgacgagc tggtcaccaa cgccctgctg
    15421 cacaccgagg gctccgcgat cgtcaccctg cgggccctgg acggcaccgg ccaccggctg
    15481 cgcatcgagg tcgaggactg ctccagcgcc ctgccgcggc gccgcgacgc cggcgagaac
    15541 ggcgtctccg gccgcggtct gctcctggtg gaccggctcg ccgacagctg gggcgtggag
    15601 gcgcggggcg gcggcaaggc ggtctggtgc gagttccggc tgccgtaggg caccggtgcg
    15661 ggcgcgacac cggggcgttg ccggtaccgg gtggcaccct ggagccatgc cggaactgcc
    15721 cgaggtacaa gcgctgacgg acttcctcac cgagcacctg gtcggactgc gggtggtgcg
    15781 ggtcctgccg gtggccgtca gcgtcctgaa gacctacgac ccgccggtca ccgccgtcga
    15841 gggcgccgag gtgacggccg tgcgccggca cggcaagttc ctggacatcg agacggacgg
    15901 cggactgcac ctggtgaccc acctggcccg cgcgggctgg ctgcagtgga aggaccggct
    15961 gccggacggc ccgccgaagc ccggcaaggg cccgctcgcg ctgcgggtgg cgctggagac
    16021 cggggagggc ttcgacctga ccgaggcggg cacccagaaa cgcctggccg tgtacgtcgt
    16081 ccgcgacccg gcggaggtgc cgggcgtcgc ccggctcggc cccgacccgc tcgccgggga
    16141 cttcgacgag gaccgcctgg ccgccctgct gaaggccgag cggcggcagc tgaagggtgc
    16201 cctgcgcgac cagtcgctga tcgcgggcgt cggcaacgcc tacagcgacg agatcctgca
    16261 cgccgcgaag atgtccccct tcaaactcgc cgcgtcgctc accccggagg agacccaccg
    16321 cctgtacgag gcgctgcgcg gcacgctcac cgaggcggtc gagcggtccc ggggagtggc
    16381 ggccggccgg ctgaaggcgg agaagaagag cggtctgcgg gtccacggcc gcaccggcga
    16441 accctgcccg gtgtgcggcg acaccatccg ggaggtctcc ttcgccgact cctcgctgca
    16501 gtactgcccg acctgccaga cgggcggcaa gccgctggcc gaccggcgtc tgtcccggct
    16561 gctgaagtga gtccgggcac ctcaagtccg ggcacctccc ggtgccgtca ccgtgcctcc
    16621 agcacgacca gccgctttcc gtcgtccgtg cggacctcgt agcgctggat ctggtccggg
    16681 tgcagggcgg tggagcccat cgcggtggtg ggccggctgc cgtcacccgc gttggtccac
    16741 ccggcgacgt cctgctccgt gccgtcgagg ccgaccgcga ccagccggca ggtgtgccgc
    16801 ccggagccgt ccttgacctc cagcctgagg tcgctgcccc agtcctcgtc ctcggaggtg
    16861 acccgcgccc acaccccggt gtgcggatcg gtcgccgcgg tgacccgcgg ggccggcccc
    16921 gcgtggccgg cgaaggccac gatcgccggg ccggccacgg ccagcaccac cgaggcggcc
    16981 aggccgtaca gcagccggcg gcgccgtgcc cggtgccgtt gcgccagctc gccgagcagc
    17041 cggtccagca gccggggacc gggctgcgcc atggggtgca cgaaacgcgg cgtggcccgg
    17101 cggtacagca acagctgccg ggacgtggga ccgaactcgg tcacctgtgc cgcgcaccgt
    17161 gagcactcca tgaggtggtc ctcgaagcgg aaggcctccg cctcgtccag cacgccgagc
    17221 gcgtacgcgc cgacgtcgcg atgcctttcc agggacctca tgccgaatcc tcgtgcctat
    17281 gggtgcgggt ggggttactc cttgctccca tccgtacgca ggcgaccgcc gaatcactca
    17341 agccacgcac agaatcccgg acaagagatt cggagcggcc cggcccgtgg attggtgtga
    17401 attccagaag attcagaaga ggtggatcgc gaggtgcccg aggggcagtc cgagccgcca
    17461 ggccggcgtc cacaccttcg gcccctcgtc ctccccgaac accgcgccgc cgcccggcac
    17521 cgcgtccagg tccggggcga gcagctccgt ctcctccagc cagcgccagg cgtcctccgc
    17581 cagtgccagg tccggacagg gggcgccgga gaccgccgcc ccctcggtca gctcggccat
    17641 gcgggcccgc acccagtcct gccacggctg gtcgtacgcg gtcagggcca gccagttctc
    17701 cagctgggag atcacccgga tgccggagag ctccccgtcg gtgtcggaga ggaagacggt
    17761 cagtgccagc gcgtcccggc cggcccggaa ctcgaaggac gtcggcggca tcagatcgcc
    17821 ggtgcgcagc agctcgtcgg cgatgtactc ggcgtacaac caggccatgg ggacggccag
    17881 ttcatggccg tcggtgccgt ccgtgctctc gtgacctctg tgtcgcatcc cttcctgccc
    17941 ttcctccggt gcgtgcgcgt cgcccgggcc ctgccgggac cgccgtcccc gctccgcccg
    18001 gaacgcgtat gaggacagcc cattgcccga acgggggcca cagcaaggcg ctttaccgag
    18061 gtttgaccag gcttccggtt tcatcgcagg tcggccgcgt aacccggaag gacccggcgc
    18121 agggcgcgca acgcgtagta cgcgcgggat ttcacggtac cgggtggaat ccccagggcc
    18181 tgcgccgcct ccgccacact ggccccgcgg aaatacacca gtatcaggac gtcacggtgc
    18241 tccggcgtga gtgtcttcac agcctcccgg acgtcgagca tcgccgcggc ccgctcggcg
    18301 tggtcggcgg tcacccgcgc gttctcgggg acttcgtcgc cgacctcggg cggccgcgcc
    18361 tgccgggccc gccgggcgtc gatcgcgagc cgccgggcca cggtgagcag ccagggccgt
    18421 acggagtcga agtcgtcggc gtgcagtgcc tccgggtgct gccaggcgcg caccagggtc
    18481 tcctggacga ggtcctcggc gcgctggcgg tccccgtcgc agagcctgag cagcagcgcg
    18541 aacagcgggc caccgtgctc gcgctggagc gcggccagct cgtgcccggc ggtcgtggtc
    18601 ccgatggtga gtgaggttcc ggccgtcatg gccgtatgcc agcgcaggcc gcggccggcc
    18661 gacagaccgc ggacccgctc gtgcgacgga cggtcgatcg cgtcggcgaa cggtcggacg
    18721 agtggtacgt cagggcaccg gacgggctaa tgaggccacc tggactgttt atccgggaca
    18781 tcagattcat acccatatgc ccgtcacggc ttcgtctgta tatacgacaa tgctggggtg
    18841 agttgatgat cggacgcaga cagcaggtgg ccctggccct gaccgccgtg ctcgcggccg
    18901 gggcggcctg ccagaaccag aaccaggaat ccggcacgcg gggacagccg gcgcccgccg
    18961 cgaccagcgg cggcggcttc accctcgtcg cctccggaga cgtcctgccg cacacctccg
    19021 tcatcgagcg ggcggcctac gacgccgacc ggaacggcca cgacttccgg cccatgctct
    19081 ccggcgtcca gccggtcgtc tcccgtgccg acctggcact ctgtcacatg gacaccgtct
    19141 acggcgccga cggcgactac accggctacc ccgtcttcaa gtcccctccg cagatcgccg
    19201 aggccctcgc cgcgaccggc tacgacagct gttccaccgc ctcagcccac gccctggacg
    19261 acggcaccgc cggcatcggg cgcaccctcg acgcgatgga ccgggccggg ctgcggcacg
    19321 ccgggaccgc ccgcagcgag aacgaggcgc gctcggtgcg cttcctccgg gcgggccggg
    19381 ccaaggtcgc ccatctgtcg tacaccttcg gcacgaacta cccgatgcca cccggacagc
    19441 cctgggcggt caacctgatg gacgccgaac ggatgatcgc cgacgcccgg gccgcccggc
    19501 ggggcggcgc cgacgtggtc gtggtctccg tggactgggg caccgagtgg caggaggaac
    19561 ccgaccggat ccagctcacc ctcgcccagc agctcaccgc ctcggccacc gacggccgcc
    19621 cggacatcga cctgatcctc ggcacccacg cccatgtgcc gcaggcctac gagaaggtca
    19681 acggcacctg ggtggtctat ggactgggcg accagatcgc cggcgagatg tacaaccggg
    19741 agggcgccca ggacccgcgg ggcaacgagt ccagcctcgg ccgcttcacc ttcgtcccgc
    19801 ccgcccggcc cggcgggccc tggcgggtca ccagggccga gttcctgccg cagctgtacg
    19861 acctcgacgc cggccgggtc gtcgacctga accgggccat cgcccagggc gccgacctgg
    19921 aggccgtgcg cgaccggatc gggaaggccg tcctcagccg cggggccgcc caggacggcc
    19981 tggtcatggg cgagtgatca gtcggcgggc cgctgcgtgg cgagcaccga gcgccggtag
    20041 gagtagccga agtagatcac gcagccgatc aggaaccaca ccacgaaccg cacccacgtc
    20101 tcccacttca ggaacgtgat cagccagacc gagaagacga cacccagcgc gggcacgaac
    20161 ggcatccacg gcgtccggaa ggtgcgcggc agctccggct gccggtagcg cagcacgatc
    20221 accgccacgc acaccaccac gaacgccagc aggatgccga tgttggtcag ctcggccgcc
    20281 tcgccgatcg ggaccagccc ggcgatgacc gcggacgccg ccccgacgat ccaggtcacc
    20341 cgggtcggca cgtgccgcgt cgggtgcgtc ttcgcgaacc accggggcag cagcccgtca
    20401 cgggacatcg agaaccacac ccgggtgacg cccagcatga acgtgaacat caccgtgagg
    20461 atgccgatga t
//
