LOCUS       NZ_JACHGT010000034      3863 bp    DNA     linear   CON 26-SEP-2024
DEFINITION  Phytomonospora endophytica strain YIM 65646 Ga0310468_34, whole
            genome shotgun sequence.
ACCESSION   NZ_JACHGT010000034
VERSION     NZ_JACHGT010000034.1
KEYWORDS    WGS; RefSeq.
SOURCE      Phytomonospora endophytica
  ORGANISM  Phytomonospora endophytica
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Phytomonospora.
REFERENCE   1  (bases 1 to 3863)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3863)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2020) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 173.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014202425.1-RS_2024_09_26
            Annotation Date                   :: 09/26/2024 09:39:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,840
            CDSs (total)                      :: 7,783
            Genes (coding)                    :: 7,704
            CDSs (with protein)               :: 7,704
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 21 of 79
            Pseudo Genes (incomplete)         :: 67 of 79
            Pseudo Genes (internal stop)      :: 5 of 79
            Pseudo Genes (multiple problems)  :: 14 of 79
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:30:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 3863
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JACHGT010000034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     aSDomain        complement(<1..1127)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HNR73_RS38925_AMP-binding.1"
                     /evalue="2.60E-97"
                     /label="HNR73_RS38925_AMP-binding.1"
                     /locus_tag="HNR73_RS38925"
                     /protein_end="1288"
                     /protein_start="912"
                     /score="317.9"
                     /specificity="substrate consensus: Gly"
                     /tool="antismash"
                     /translation="EDAADLTPDAVAVIDGRQRLTYAELDRRANQFARRLLQEDVAGGE
                     LIGVALPRSATLVAVLLGIQKAGLAYVPLDPGLPRERIEYIVEDAAITTIISDDAHREQ
                     LQESGSTVLALDRTELDRIGAMNADRLDLAVDPRDLAYVIYTSGSTGRPKGVAVEHGGC
                     TDRLAGARRLFAVAPGDRVLARTPISFDISVWETFLPLSAGATVIMAAPSSRHDDGYLS
                     ELIRGERVTVAQFTPSGLLTLAEGGAGASHPSVRLLWLGGERLDRHVIEHAVKVFPEAR
                     IVNMYGPTEASVWATWWDCGTPIDGSTVPIGHALQNVAIHILDPQGHEVPVGGVGELCI
                     GGIGVARGYLARPGLTADKFIPNPHTTDGTRLYRTG"
     aSModule        complement(<1..2486)
                     /domains="nrpspksdomains_HNR73_RS38925_Condensation_DCL.1"
                     /domains="nrpspksdomains_HNR73_RS38925_AMP-binding.1"
                     /incomplete
                     /locus_tags="HNR73_RS38925"
                     /tool="antismash"
                     /type="nrps"
     source          1..3863
                     /db_xref="taxon:714109"
                     /geo_loc_name="China: Yunnan province, Kunming"
                     /lat_lon="25.07 N 102.68 E"
                     /mol_type="genomic DNA"
                     /organism="Phytomonospora endophytica"
                     /strain="YIM 65646"
                     /submitter_seqid="Ga0310468_34"
                     /type_material="type strain of Phytomonospora endophytica"
     gene            complement(<1..>3863)
                     /locus_tag="HNR73_RS38925"
                     /old_locus_tag="HNR73_007940"
     region          1..3863
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..3863
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..3863
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:3863](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..3863)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             complement(<1..3863)
                     /NRPS_PKS="Domain: Epimerization (29-325). E-value:
                     2.2e-68. Score: 222.6. Matches aSDomain:
                     nrpspksdomains_HNR73_RS38925_Epimerization.1"
                     /NRPS_PKS="Domain: Condensation_DCL (459-753). E-value:
                     1.8e-72. Score: 235.9. Matches aSDomain:
                     nrpspksdomains_HNR73_RS38925_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (912-1288). E-value:
                     2.6e-97. Score: 317.9. Matches aSDomain:
                     nrpspksdomains_HNR73_RS38925_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="HNR73_RS38925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_007940"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_184793112.1"
                     /sec_met_domain="Condensation (E-value: 1.9e-55, bitscore:
                     174.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5e-96, bitscore:
                     307.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHQTINELTTIATHNTNTPTPTPTPQNNTPLAPIQEWFFAQTFQ
                     QPHHWNLSTATAFDEPVDVAALAEALNGLVAHHDELRARFDSADDGDRRRRLAPTDSGR
                     WPLTVLLDGDAEEVAAALDTAQADMGLTEGPLTSAVLVRPSDGNGEAQLVLTCHHLVVD
                     AVSWTILVEDLHTAYRQRLLRAPIDLPAKTASYGQWAAELSANVQAGALDDEVVHWRSV
                     PAFPLSVPGIGAEDPADGAGETLRQQRTGIELSRALRDHATRRHGARLEELMIAALVCA
                     VGDVGQTGGVSLLREIHGRQHEISDLDTSRTVGWFTGMHPVTVALSDDGDVVSVLRDVK
                     RFLRNMPRKGAGFLPLRELTGHLDGFDEPSVTFNYLGHTVFPSGVVAQDSTAVGFGTER
                     ARDEHRPHALEVVTFLEGDELVVDWIAPGSPAAQETLDLLCGRLVEQLRLLAVPDGPVA
                     GDVIALTSTQEGVLFDAMFDEPGSGRYVERLEYELTGVAGVEELHHAWREVCGRHAMLR
                     ARLVWTDQGTALLESSPVAEVPFTTLEAGSQAEFEAIRERELTAPMAVNDPSLTRMTVV
                     RTPSGEHHLFWVFHHLLLDGWSAAVLLDEFKTVHDARSRGEVPVLPAAPRLNEYVSWLR
                     RTTQRHDSHDEFWRRRLDGHVRTNTLAPMDAPSEHPRPETYEFGIPDDLTAELGSVTRA
                     LRITLNTVVRAAWALTLGAYTASTDVVFGATLSGRSSQFVNSERFVGMLINTLPVRIGI
                     DPAQPVQDWLVRIQADSVDLLEHQHSSLSRIKSLVGDQRDLFDTLVLFQNFPQPTEDAD
                     TGLLFRTVTAVEWTGYPLTLRIHPGSSLRADLTFDARRPPLPAADVARTFVRVLRSIAE
                     QNESATVSDLRRTSDEDARRTRTWNARVRTAKTAGTLHRLVEDAADLTPDAVAVIDGRQ
                     RLTYAELDRRANQFARRLLQEDVAGGELIGVALPRSATLVAVLLGIQKAGLAYVPLDPG
                     LPRERIEYIVEDAAITTIISDDAHREQLQESGSTVLALDRTELDRIGAMNADRLDLAVD
                     PRDLAYVIYTSGSTGRPKGVAVEHGGCTDRLAGARRLFAVAPGDRVLARTPISFDISVW
                     ETFLPLSAGATVIMAAPSSRHDDGYLSELIRGERVTVAQFTPSGLLTLAEGGAGASHPS
                     VRLLWLGGERLDRHVIEHAVKVFPEARIVNMYGPTEASVWATWWDCGTPIDGSTVPIGH
                     ALQNVAIHILDPQGHEVPVGGVGELCIGGIGVARGYLARPGLTADKFIPNPHTTDGTRL
                     YRTG"
     CDS_motif       complement(48..137)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HNR73_RS38925_0010"
                     /evalue="1.00E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="HNR73_RS38925"
                     /protein_end="1272"
                     /protein_start="1242"
                     /score="49.8"
                     /tool="antismash"
                     /translation="PVGGVGELCIGGIGVARGYLARPGLTADKF"
     CDS_motif       complement(648..707)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HNR73_RS38925_0009"
                     /evalue="4.50E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="HNR73_RS38925"
                     /protein_end="1072"
                     /protein_start="1052"
                     /score="34.4"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVAVEH"
     CDS_motif       complement(903..944)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HNR73_RS38925_0008"
                     /evalue="2.10E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="HNR73_RS38925"
                     /protein_end="987"
                     /protein_start="973"
                     /score="14.7"
                     /tool="antismash"
                     /translation="LGIQKAGLAYVPLD"
     CDS_motif       complement(1449..1565)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HNR73_RS38925_0007"
                     /evalue="1.40E-11"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="HNR73_RS38925"
                     /protein_end="805"
                     /protein_start="766"
                     /score="36.7"
                     /tool="antismash"
                     /translation="QADSVDLLEHQHSSLSRIKSLVGDQRDLFDTLVLFQNFP"
     aSDomain        complement(1605..2486)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HNR73_RS38925_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.80E-72"
                     /label="HNR73_RS38925_Condensation_DCL.1"
                     /locus_tag="HNR73_RS38925"
                     /protein_end="753"
                     /protein_start="459"
                     /score="235.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLLLDG"
                     /tool="antismash"
                     /translation="DVIALTSTQEGVLFDAMFDEPGSGRYVERLEYELTGVAGVEELHH
                     AWREVCGRHAMLRARLVWTDQGTALLESSPVAEVPFTTLEAGSQAEFEAIRERELTAPM
                     AVNDPSLTRMTVVRTPSGEHHLFWVFHHLLLDGWSAAVLLDEFKTVHDARSRGEVPVLP
                     AAPRLNEYVSWLRRTTQRHDSHDEFWRRRLDGHVRTNTLAPMDAPSEHPRPETYEFGIP
                     DDLTAELGSVTRALRITLNTVVRAAWALTLGAYTASTDVVFGATLSGRSSQFVNSERFV
                     GMLINTLPVRIGI"
     CDS_motif       complement(1614..1709)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HNR73_RS38925_0006"
                     /evalue="5.70E-13"
                     /label="C5_DCL_263-294"
                     /locus_tag="HNR73_RS38925"
                     /protein_end="750"
                     /protein_start="718"
                     /score="41.3"
                     /tool="antismash"
                     /translation="DVVFGATLSGRSSQFVNSERFVGMLINTLPVR"
     CDS_motif       complement(2040..2099)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HNR73_RS38925_0005"
                     /evalue="1.10E-08"
                     /label="C3_DCL_135-156"
                     /locus_tag="HNR73_RS38925"
                     /protein_end="608"
                     /protein_start="588"
                     /score="27.6"
                     /tool="antismash"
                     /translation="FHHLLLDGWSAAVLLDEFKT"
     CDS_motif       complement(2298..2411)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HNR73_RS38925_0004"
                     /evalue="1.70E-06"
                     /label="C2_DCL_024-062"
                     /locus_tag="HNR73_RS38925"
                     /protein_end="522"
                     /protein_start="484"
                     /score="20.3"
                     /tool="antismash"
                     /translation="YVERLEYELTGVAGVEELHHAWREVCGRHAMLRARLVW"
     aSDomain        complement(2889..3776)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HNR73_RS38925_Epimerization.1"
                     /evalue="2.20E-68"
                     /label="HNR73_RS38925_Epimerization.1"
                     /locus_tag="HNR73_RS38925"
                     /protein_end="325"
                     /protein_start="29"
                     /score="222.6"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDA"
                     /tool="antismash"
                     /translation="TPLAPIQEWFFAQTFQQPHHWNLSTATAFDEPVDVAALAEALNGL
                     VAHHDELRARFDSADDGDRRRRLAPTDSGRWPLTVLLDGDAEEVAAALDTAQADMGLTE
                     GPLTSAVLVRPSDGNGEAQLVLTCHHLVVDAVSWTILVEDLHTAYRQRLLRAPIDLPAK
                     TASYGQWAAELSANVQAGALDDEVVHWRSVPAFPLSVPGIGAEDPADGAGETLRQQRTG
                     IELSRALRDHATRRHGARLEELMIAALVCAVGDVGQTGGVSLLREIHGRQHEISDLDTS
                     RTVGWFTGMHPVTVA"
     CDS_motif       complement(2892..2942)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HNR73_RS38925_0003"
                     /evalue="3.10E-07"
                     /label="NRPS-E5"
                     /locus_tag="HNR73_RS38925"
                     /protein_end="324"
                     /protein_start="307"
                     /score="22.6"
                     /tool="antismash"
                     /translation="DTSRTVGWFTGMHPVTV"
     CDS_motif       complement(3342..3407)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HNR73_RS38925_0002"
                     /evalue="3.40E-10"
                     /label="NRPS-E2"
                     /locus_tag="HNR73_RS38925"
                     /protein_end="174"
                     /protein_start="152"
                     /score="32.2"
                     /tool="antismash"
                     /translation="LVLTCHHLVVDAVSWTILVEDL"
     CDS_motif       complement(3609..3716)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HNR73_RS38925_0001"
                     /evalue="3.00E-08"
                     /label="C2_LCL_024-062"
                     /locus_tag="HNR73_RS38925"
                     /protein_end="85"
                     /protein_start="49"
                     /score="26.1"
                     /tool="antismash"
                     /translation="WNLSTATAFDEPVDVAALAEALNGLVAHHDELRARF"
ORIGIN
        1 ccggtgcggt agaggcgggt gccgtcggtg gtatgggggt tgggaatgaa tttgtcggcg
       61 gtgaggccgg gacgcgccaa ataaccacgc gcgacaccga ttccgccgat gcacagttca
      121 cccactccgc cgacgggcac ctcgtggccc tgcgggtcga gaatatgaat cgcgacattc
      181 tgcagcgcat gcccgatcgg caccgtcgag ccgtcgatcg gcgttccgca gtcccaccag
      241 gtcgcccaga ccgatgcctc ggtggggccg tacatgttga cgatccgggc ctctgggaag
      301 accttcacgg cgtgttcgat gacgtgccgg tcgaggcgtt caccgccgag ccacaacagg
      361 cgcaccgagg gatgggacgc gccggccccg ccctcggcca gtgtgagaag acctgagggc
      421 gtgaactgtg cgacggtcac ccgctcaccg cggatcagtt cggacagata cccgtcgtcg
      481 tgccgggagc taggggcggc catgatgacc gtcgccccgg ccgacagcgg caagaaggtc
      541 tcccacaccg agatgtcgaa gctgatcgga gtgcgcgcga gcacgcgatc cccgggagcg
      601 accgcgaaca gccgccgggc accggcgagg cggtcggtgc agcctccgtg ttcgacggcg
      661 acgcccttcg gtcgaccggt tgagcccgag gtgtagatga cgtacgcgag gtccctcggg
      721 tcgacggcga ggtccagccg atcggcgttc atggcgccga tccggtcgag ttccgtacgg
      781 tcgagggcga gcacggtcga cccgctctcc tggagctgtt cccggtgcgc gtcgtcactg
      841 atgatggtgg tgatggccgc gtcctcgacg atgtactcga tccgttcccg tggaaggccc
      901 ggatcgaggg gcacataggc gagtcccgcc ttctgaatgc cgagaagcac ggcaaccagc
      961 gtggcgctgc gcgggagggc gaccccgatg agttctccgc ccgcgacgtc ttcctggagg
     1021 agccgacgag cgaactggtt ggcgcggcgg tcgagttcgg cgtaggtgag ccgctgtcgc
     1081 ccgtcgatga cggcgaccgc atccggggtc aggtccgcgg cgtcctccac tagccggtgc
     1141 aacgtgccgg cggtcttcgc ggttcggacc cgagcgttcc aggtgcgcgt gcggcgggcg
     1201 tcctcgtcgc tggtgcgccg caggtccgag acggtggcgg actcgttctg ctccgcgatg
     1261 cttcgcagca cccggacgaa ggttctggcc acgtcggcgg cgggcagcgg gggccgtcgc
     1321 gcgtcgaagg tcagatccgc gcgcagactg gagccggggt ggatcctgag cgtcagcgga
     1381 tacccggtcc actcgaccgc cgtcaccgta cggaagagca gaccggtgtc ggcgtcctcc
     1441 gtcggctggg gaaagttctg gaagagcacc agggtgtcga agagatcccg ctgatctccg
     1501 acgagtgact tgatgcgcga caacgagctg tgctggtgtt cgagcagatc caccgaatcc
     1561 gcctggatcc ggaccagcca gtcctggacc ggctgcgccg gatcgatgcc gatccgcacc
     1621 ggcaacgtgt tgatcagcat gccgacgaac cgctcgctgt tgacgaactg gctcgaccgc
     1681 cccgacaacg tcgccccgaa caccacatcg gttgaggccg tgtaggcgcc caacgtcagt
     1741 gcccacgcgg ctctcaccac ggtgttgagg gtgatgcgca gagcgcgggt gaccgatccg
     1801 agctcggcgg tgagatcgtc gggaatgccg aactcgtatg tttcgggccg agggtgctcc
     1861 gagggtgcgt ccatcggtgc gagagtgttc gtcctgacgt gtccgtcgag ccgccgccgc
     1921 cagaactcgt catgggagtc gtggcgctgc gttgttcgcc gcagccagga cacgtactcg
     1981 ttgaggcgcg gcgccgcggg caggaccggc acctcacccc gtgatcgcgc gtcatggacg
     2041 gtcttgaact cgtcgagcag tacggcggcg ctccagccgt cgagcagcag gtggtggaag
     2101 acccagaaca ggtggtgctc gcccgacggt gtgcgcacca ccgtcatacg cgtcagcgat
     2161 gggtcgttga ccgccatcgg agcggtcagt tcccgctcgc ggatggcttc gaactccgcc
     2221 tgactgcctg cttccagtgt ggtgaaagga acctcggcaa cgggtgagct ttcgagcagg
     2281 gcggttccct ggtccgtcca gacgagcctc gcacgcagca tggcgtggcg gccgcacacc
     2341 tcgcgccagg catggtgtag ctcttcgacg cccgcgaccc cggtgagttc gtactcgagc
     2401 cgctcgacgt accgcccgga ccccggctcg tcgaacatcg cgtcgaacaa cacgccctcc
     2461 tgcgtggagg tgagcgcgat gacatccccg gccactggcc cgtccggcac ggcgagcagg
     2521 cgcagctgct ccaccagacg gccgcacaga agatcgagag tctcctgagc ggccggcgat
     2581 ccgggcgcga tccagtcgac cacgagctcg tcgccttcca ggaaggtgac cacctcaagg
     2641 gcgtgtggcc ggtgttcgtc gcgggcccgt tctgtgccga aacccaccgc ggtggagtct
     2701 tgcgccacca cgcccgaggg gaagacggtg tgtccgaggt agttgaaggt gacggagggc
     2761 tcgtcgaatc cgtcgaggtg gccggtcagt tcacgcagtg gcaggaagcc ggcgcccttt
     2821 cgcggcatgt tgcgaaggaa ccgcttgacg tcgcggagca cggacaccac gtcaccgtcg
     2881 tcggacaggg cgaccgtgac gggatgcatg ccggtgaacc atccgaccgt gcgggaggtg
     2941 tccaggtcgc tgatctcgtg ctgacggcca tggatctcgc gcagaagaga taccccgccc
     3001 gtctgcccga cgtcgccgac cgcgcacacg agggccgcga tcatcagctc ctccagccgg
     3061 gcgccgtgcc gacgggtcgc gtggtccctg agggcccggc tgagctcgat cccggttcgc
     3121 tgctgccgaa gggtctcacc ggcgccgtcg gcggggtcct cggcgccaat cccgggaacc
     3181 gacaatggaa acgcgggtac cgaacgccag tggacgacct cgtcgtcgag tgcgcccgcc
     3241 tgaacgttcg ccgacaactc ggcagcccac tgaccgtagg aggccgtctt ggccgggagg
     3301 tcgatcggcg ccctgaggag cctctgccga taggcggtgt gcaggtcctc gaccaggatc
     3361 gtccaggaaa ccgcgtcgac gaccaggtga tggcacgtca gaaccagctg ggcctcaccg
     3421 ttcccgtcgc tcgggcgcac caggaccgcg ctggtcagcg gcccctccgt gagccccatg
     3481 tccgcctggg ccgtgtccaa cgcggcggcg acctcctcgg cgtcgccgtc caacaggacg
     3541 gtcagaggcc aacgccccga gtccgtcggt gcgagccgcc ggcggcggtc gccgtcgtcg
     3601 gcgctgtcga agcgcgcacg cagttcatcg tggtgggcga ccagaccgtt cagcgcctca
     3661 gcgagcgctg cgacatcgac cggttcatcg aatgccgtcg ccgtcgagag attccaatgg
     3721 tgaggctgct ggaatgtctg ggcgaagaac cattcctgaa tcggcgccag tggcgtgttg
     3781 ttttgtggtg tgggtgtggg tgtgggggtg ttggtgttgt gggtggcgat ggtggtgagt
     3841 tcgttgatgg tttggtgttc gaa
//
