LOCUS       NZ_JACHGT010000014     21757 bp    DNA     linear   CON 26-SEP-2024
DEFINITION  Phytomonospora endophytica strain YIM 65646 Ga0310468_14, whole
            genome shotgun sequence.
ACCESSION   NZ_JACHGT010000014
VERSION     NZ_JACHGT010000014.1
KEYWORDS    WGS; RefSeq.
SOURCE      Phytomonospora endophytica
  ORGANISM  Phytomonospora endophytica
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Phytomonospora.
REFERENCE   1  (bases 1 to 245709)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 245709)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2020) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 173.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014202425.1-RS_2024_09_26
            Annotation Date                   :: 09/26/2024 09:39:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,840
            CDSs (total)                      :: 7,783
            Genes (coding)                    :: 7,704
            CDSs (with protein)               :: 7,704
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 21 of 79
            Pseudo Genes (incomplete)         :: 67 of 79
            Pseudo Genes (internal stop)      :: 5 of 79
            Pseudo Genes (multiple problems)  :: 14 of 79
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:30:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 66333
            Orig. end                         :: 88090
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JACHGT010000014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21757
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..21757
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21757
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11757](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11757)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     misc_feature    324..337
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.71"
                     /tool="antismash"
     misc_feature    1071..1080
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     misc_feature    complement(1325..1340)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.49"
                     /tool="antismash"
     misc_feature    complement(1333..1349)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.97"
                     /tool="antismash"
     gene            1428..2528
                     /locus_tag="HNR73_RS28225"
                     /old_locus_tag="HNR73_005762"
     CDS             1428..2528
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014893.5"
                     /locus_tag="HNR73_RS28225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005762"
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="WP_184790694.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 6e-24, bitscore:
                     78.8, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 3.1e-36,
                     bitscore: 117.9, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPHPPLRLAVVGCGVIGRLHAELAAHSPDLHVAALIDPSSAATT
                     AVAEHLHRLGAPPPRVHTDLTTALADGGIDIVVICTLSGTHAQLGLEALEAGLHVVIEK
                     PLDVDVAAARHLRDAAAQRPGQVIAVISQHRHDPSARAVRRALDARRFGRITSAVANTD
                     WFRSQEYYDSAAWRGTWALDGGALMNQGVHTLDLLLWFLGEPVDVTAHTARLAHERIEV
                     EDVAVAILRFEDGALATLHATTAAYPDLGVRLQIHGTDGSAVIARDELTFFHTRDAEDI
                     DGDQVTRELAELNGGPGNSHQAQWTDIVTAIREGRTPLVDVDAGFLALTTVRAVYLSAT
                     LGRTIRVADVADGKYDGQATRTGSQT"
     gene            2729..3214
                     /locus_tag="HNR73_RS28230"
                     /old_locus_tag="HNR73_005763"
     CDS             2729..3214
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HNR73_RS28230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HNR73_005763"
                     /product="hypothetical protein"
                     /protein_id="WP_184790695.1"
                     /transl_table=11
                     /translation="MRKRIITFIALAFAVFGLLGSTAASASETGSEPAGVSSLTELKSG
                     QVGTLASEEIDYAVEHALTDPTKYCAGNGYVSGCVQPYGDVLWIKDNASNGAHVTLKWE
                     DLDGDRYGKCRNTLGADAGWARCNKDLPENHRIAWQLAYKVSSGSDWSYSPVYETRV"
     gene            complement(3340..4602)
                     /locus_tag="HNR73_RS28235"
                     /old_locus_tag="HNR73_005764"
     CDS             complement(3340..4602)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024627.5"
                     /locus_tag="HNR73_RS28235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005764"
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="WP_184790696.1"
                     /transl_table=11
                     /translation="MRHISDPVYGAVLDGVADDTAAVQLMLDAGPGSSSIAGAKIRISA
                     PLVLRTGTRLDAHGARVGGSGGHSLIRNFAPEDSFTGHDGHGDITLEGGIWDARGELAA
                     PEGPHAGAAWNAMTFAKGRRIVVRDLEIRNVASYHAVEVNACDGALIDNVTARGFLLSL
                     AHRVFSEAFQIDVAASPASSDLGEWDGTHSRDVTVRACYAGPSLDYDPSAGTGLGPFGA
                     LAGSHTHVDDRVYDGIRILDNVCEGALKYGVRAHAWRDPVIRGNTITGAGTNGVLVELG
                     AGGIVSGNVIASTASNAVNVTDTDGVIVADNTIRDTATNYGIYLSATNATAVTGNRVEA
                     AATAGLRFGTGATFCMASGNTIVRGVSAGVVAISAGAGAGTVNTAIHNQLVGYTAASVA
                     VSSGTVVVVPPAAGSAGSNVR"
     misc_feature    complement(4456..4458)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4725..5144)
                     /locus_tag="HNR73_RS28240"
                     /old_locus_tag="HNR73_005765"
     CDS             complement(4725..5144)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HNR73_RS28240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HNR73_005765"
                     /product="hypothetical protein"
                     /protein_id="WP_184790697.1"
                     /transl_table=11
                     /translation="MGFFGRKSREERNAEIVGKVASGKGFYGGLTRAFLGEADFSKVQQ
                     SIAAHNSGAYVQQLLAAGVPTFPATVVSIGDTGKLVNFEPIVDLVLDAPGAVGRIGLQT
                     IISKLQIPRAGDQVLLVGDPSQPGVYLYAGLATAP"
     misc_feature    5161..5175
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     misc_feature    5362..5377
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.51"
                     /tool="antismash"
     gene            complement(5464..5943)
                     /locus_tag="HNR73_RS28245"
                     /old_locus_tag="HNR73_005766"
     CDS             complement(5464..5943)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HNR73_RS28245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HNR73_005766"
                     /product="hypothetical protein"
                     /protein_id="WP_184790698.1"
                     /transl_table=11
                     /translation="MRSGITKYTVAAAVLATASALLIPGTASAAAPRGPGSAGEDTAAG
                     NEERPLEKNWAKLHDLTDAPRNCLDNAYVKGCVQPYGDMLWLRDDEWDGIDVRLVWIDN
                     SDPEDPRRGICQDAEGYGDWTRCDKDLPDGHEIKWTTSWWADGEWRLGKAQRIII"
     misc_feature    complement(5935..5948)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.42"
                     /tool="antismash"
     gene            complement(6137..7327)
                     /locus_tag="HNR73_RS28250"
                     /old_locus_tag="HNR73_005767"
     CDS             complement(6137..7327)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HNR73_RS28250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HNR73_005767"
                     /product="hypothetical protein"
                     /protein_id="WP_184790699.1"
                     /transl_table=11
                     /translation="MALGFEAEILRKITDNNNTVLTGDTKLVSHPWFRLVSDKVNAGNG
                     QYSNMEYVVRHVDQLAGTDQNAADLVGERVAALMLMNDELYAAQNQLVNLLTDPQPGNQ
                     AIQFYIDPVYGNTGNLNVRNCPAAGVDQGLLHIHYTVGFAPAQWRAMLNGIAPATRPDS
                     ANVRSRTHLTNGIAVADTIVNNTLNVAIGATGAQAATVRTELRGHLALLYMHAMVWIDR
                     MLANQRNDLQTAVPVNHAKLNQVLAQLPFGDGQVKNKIAALPRATLAQMWGVLSAGSRQ
                     VLSGNVDPVLNALAAKVENAHGIDFPDNYQLTSPTAGTTSLVTYITSGLNGQNGISQEV
                     LFGGMNQTGVDNSIVGHPMVPFEFRALYNAHVTWGDLRADVIRIARWSRDLTRSLV"
     misc_feature    complement(7319..7321)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7457..8275)
                     /locus_tag="HNR73_RS28255"
                     /old_locus_tag="HNR73_005768"
     CDS             complement(7457..8275)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.5"
                     /locus_tag="HNR73_RS28255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005768"
                     /product="ABC transporter permease"
                     /protein_id="WP_184790700.1"
                     /transl_table=11
                     /translation="MTTLSLSGAPQSRARHGRLADLKAVLYREFMLLTRNRVNLVLSTV
                     HGFIYLLLLSTSLSNMISVVGYAGTEVSYLVFALPTVLMTAVLSASANSGTALFQEDAS
                     KMALALWSYPLRRFSYIAGKLIASVALVLVQAFLALGVGTLLFRFPLTAENWLALLLAT
                     LVVSAAFNALYMLLGAYIRDFQSFNIVVNLSVPVLLFSSPSFYSEESMPTVLRWISTVN
                     PVTYGLRGLRDATIVGFSAAWPWLAGLAVAAAAGYWTVAWALLRRTRQML"
     gene            complement(8272..9213)
                     /locus_tag="HNR73_RS28260"
                     /old_locus_tag="HNR73_005769"
     CDS             complement(8272..9213)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.5"
                     /locus_tag="HNR73_RS28260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005769"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_184790701.1"
                     /transl_table=11
                     /translation="MTVVIETEHLSKTYPGSDVPAVDDVSFRVAEGEVIGLLGPNGAGK
                     TSLIKLICGVTTASSGSLRVFGADPVTDPVTAKSALGVMHQSAPFDLMLNVVDNLKIGA
                     RFADRRWREVKDWVAELLDLFELTPAVRKPAFQLSGGQRQRLQLVRALITLPKVLVLDE
                     PTTGLDVSGRRQVWETVAKLRAEYAVSVLWTSHYIEEIERNCERILLLHKGRLLRDADP
                     AAIAAEFGSSGVRAELTDPAHAASLLAWATERGLNGEADELGVEITGKDARERMPELVR
                     FAHDEHIELAGVSVFAASLEDAFVALTVKESR"
     gene            complement(9210..10004)
                     /locus_tag="HNR73_RS28265"
                     /old_locus_tag="HNR73_005770"
     CDS             complement(9210..10004)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HNR73_RS28265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HNR73_005770"
                     /product="S26 family signal peptidase"
                     /protein_id="WP_184790702.1"
                     /transl_table=11
                     /translation="MTAAAAALVRRALARLGRAVIDVAGTSMAPTIVAPARVTLTARRF
                     ENVVVGDVAAYLAGEDIVVHRVVHRDADRLFTAGDARRRVDPAAHRGDFLGVVEGLAPF
                     TAPSPMKLVPAPTGAGPAAVRLWVFEHGATWSTTDTDGLTVTRLPRAGIGADPGVVERL
                     RAETTGSDLRIGVCQSARDGIELLTALDLTAYGTVDVVTGVGFTTAAPPLADGTVLLPE
                     DLAHVFVRTAPLGEWPTTAWVTETLVPQLSPVPAGPAGRRPR"
     gene            complement(10001..10294)
                     /locus_tag="HNR73_RS28270"
                     /old_locus_tag="HNR73_005771"
     CDS             complement(10001..10294)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.5"
                     /locus_tag="HNR73_RS28270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005771"
                     /product="PqqD family protein"
                     /protein_id="WP_184790703.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 3.2e-13,
                     bitscore: 43.3, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.9e-13, bitscore: 42.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNPWIIAEQIVWSADSGEIRLYDALEGTFQTLNASGTAIWELVV
                     EGLGTEEIAARLSSLYGEDDEAERKLIAEDVHAFLADLATRGVVSPATAAAP"
     aSDomain        complement(10025..10267)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HNR73_RS28270_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="4.20E-14"
                     /identifier="RREFam002.1"
                     /label="HNR73_RS28270"
                     /locus_tag="HNR73_RS28270"
                     /protein_end="90"
                     /protein_start="9"
                     /score="43.3"
                     /tool="antismash"
                     /translation="QIVWSADSGEIRLYDALEGTFQTLNASGTAIWELVVEGLGTEEIA
                     ARLSSLYGEDDEAERKLIAEDVHAFLADLATRGVVS"
     gene            complement(10294..11757)
                     /gene="stsB"
                     /locus_tag="HNR73_RS28275"
                     /old_locus_tag="HNR73_005772"
     CDS             complement(10294..11757)
                     /codon_start=1
                     /gene="stsB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015622287.1"
                     /locus_tag="HNR73_RS28275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005772"
                     /product="StsB family radical SAM/SPASM domain sactipeptide
                     maturase"
                     /protein_id="WP_184790704.1"
                     /sec_met_domain="PTHR43273 (E-value: 3.8e-49, bitscore:
                     161.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5e-14, bitscore: 46.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3.4e-25, bitscore: 83.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 7.1e-10, bitscore: 32.4,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3.5e-15, bitscore:
                     49.9, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.9e-10, bitscore: 34.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLISGQLDALVVPDDIVVFRAANGDRFALNPTLAAWGRLTPRQDE
                     ILCALARRDLAFFHPDDFGLALEKDLAQLVVNFLAYLPGHEPQRSEHVVELRIVYYAIT
                     DGCNLRCPYCYASSEKALPGELSHEESLRLVEQAAELGAGTMVFTGGEPMMRRDLFDVV
                     RHARSLGMRTNIITNGTLIRNAKTAETMSELFDMVTVSMDGATAEQHEKTRGRGTFAKT
                     STGLRLLNDAGVVPMINHVVTNDNVQYLEDFADFAGQFKLQRVRMMQHSDLGRGQGDDL
                     SFGWGEYMKIHDFAWTHPKAKNMLPDHVTPEKPCNVRANCGMGSNEIYVNSLGAVYPCK
                     LVTSPKDLAGNVKASSLREIFNGELFAEFQNSTIFGGTVHTDCERCYIKGACGGGCRAY
                     HLAQSGDLRKNSRQLCRILRHQKISSIWHSLGASGDTLVGDSEAFQPRLARNGEVHPVY
                     EDWRTELAATPPASPQTPSRRLLNIVEAR"
     misc_feature    11910..11923
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.28"
                     /tool="antismash"
     misc_feature    complement(12226..12238)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    12252..12266
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.69"
                     /tool="antismash"
     gene            complement(12501..15284)
                     /locus_tag="HNR73_RS28280"
                     /old_locus_tag="HNR73_005774"
     CDS             complement(12501..15284)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="HNR73_RS28280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005774"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_184790705.1"
                     /transl_table=11
                     /translation="MRFEVLGPLRLQTEGVTAHIDGPKQRALLAALISRAGRPASPATL
                     YEGLWGGRLPTSPRRALTWHIRQLRKLLDRPDRLVWRQTGYVLAAEATEVDASCFTTLR
                     EAGLAAQRAGDTAHAGALFAEALGLWRGEAYADVPEHAIPEGEAARLERLRLDVLAHRV
                     TADLTLGRHEALLPELTALSAAHPLDEGIRANLMLALHRCGRRADALEAYREGRAILVA
                     ELGLEPGPRLRRAEKEVLTDEAGPEPAAATSGPAELPAAPRTFTGRADDVAAVLDVFAA
                     PGAVCAIAGPGGIGKSAIALHIAHHLAREFPDGQLYVDLHGTTPDVKALQPEEALRRFL
                     RSLQGPASASALGVEELAGRFRSATAGKRLLIVLDDARDAAQVRPLLPGGPACAVVITS
                     RRVLSTLDEATIHRLEALPDAEAIGVLARLLGIERVAAETEAAADIAGHCGGLPLALVI
                     AAARLRARPTMPLSALAARLAAEDARLGELAVDDRAVRASFAVSLAELADDMGGGPALR
                     LFGLLGAVDTPDMSVPAAAALADVGEREAEGLLAGLVDAQLLEQSGDRFHLHDLMRLFA
                     KEQPLSPAEAAGGFTRILGYYVGAARATIGVIEPRATVRREYRVGPSERAGTPPSDRTA
                     ATRWVQGELDNLRAVMRQAVLLGDETATTLAHLLTTPLDYIKELPALREIGDQALAIAE
                     SVGDRELMLVAHRDLAEVLVASERADEALPHLAVAREAARLMADRHTEAILLGLTDGAH
                     SLLDRHAEALDAYARSVELARECGLEQTEGATLNAMGHLLRQVGDLPAALDAQQRAQAI
                     AERLGSPHGQALTSSSVAGIHMELGNYREAAEHYGHAIVMNREAGQEEALVAADYAWGL
                     AEALYAMGRVGEALASWGVSLDVLHRFGAITADERESLGASEHPRQPDAISLPVVE"
     misc_feature    complement(15138..15140)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            15738..15995
                     /locus_tag="HNR73_RS28285"
                     /old_locus_tag="HNR73_005775"
     CDS             15738..15995
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HNR73_RS28285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HNR73_005775"
                     /product="hypothetical protein"
                     /protein_id="WP_184790706.1"
                     /transl_table=11
                     /translation="MSDGTQPADCPWDESFVIAPDRTIWHAWPRSGGWKEMPNYGKADF
                     ATNCYYNGNNKHQIDVWVQYTGAYYYSYHSGGAWHGWYRN"
     gene            16097..16477
                     /locus_tag="HNR73_RS28290"
                     /old_locus_tag="HNR73_005776"
     CDS             16097..16477
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012371.5"
                     /locus_tag="HNR73_RS28290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005776"
                     /product="serine hydrolase"
                     /protein_id="WP_184790835.1"
                     /transl_table=11
                     /translation="MGAAGGVGSARGLSRMYSWLLDAFEPGTVADIPRPETSGSDLVPS
                     SPAMSVEQRFGRGFMVPSAEETPARSATFGHEGAGGTTAFADPGGGLAFAYATTRIALG
                     PPDTDPRAEALITSVYQALRTG"
     gene            16742..17548
                     /locus_tag="HNR73_RS28295"
                     /old_locus_tag="HNR73_005777"
     CDS             16742..17548
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013700.5"
                     /locus_tag="HNR73_RS28295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005777"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_184790707.1"
                     /transl_table=11
                     /translation="MPRYLMHLARKAVDGTGEYVGRVTPVLRKRLSGLSALVARSARVA
                     APVVVGVRRRFPRLSGALETSVPRVGLAAAMLTAILLVVFMANFAGAITGGTPSDASAA
                     VGARGTQEDQSSRDQERGTEPAEKPRPTKPVKAKSGWAAPSTAELSDHYGPRGWRDGEM
                     HWGMDFAADKGDKIYAAFNGTVVMAQRYGGYGNCVVIKHAGGVQTLYGHFSKLDVSAGD
                     EVKTGDLLGRAGSTGDSTGPHLHFEVTVNGSYLDPEKFLEKKGVDF"
     gene            complement(17597..19912)
                     /locus_tag="HNR73_RS28300"
                     /old_locus_tag="HNR73_005778"
     CDS             complement(17597..19912)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HNR73_RS28300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HNR73_005778"
                     /product="hypothetical protein"
                     /protein_id="WP_184790708.1"
                     /transl_table=11
                     /translation="MKSDRSTPTMTRRGLLGAALAAGVVLAAEAAPVGAWAADGDVTLS
                     ANGVSALASIGGRIAIRDGQATVRSAGSKFQIKDSATGIHLSTGGTPSLVTLADGTPAI
                     RVDYTMPAAAGAVAVHALVTVSTDHVHLSWHVTGPATLVPDGFLFSRAIQNPTEADAYV
                     AITEWVRDDDGGVPYETTLGVAHASTWGTRHGMFLLERSRQAWTNATWIHAPGTTQADG
                     SHLSEADFFFTTRRPSATASIGTSRELGVEIWTDRPFNIWETPGAAMTVNVQVANGSPS
                     ARDVALSWWVKDFDGHELAEATVTATVAATSTWEHTFTVAAPANGIALAEVTARSGTDE
                     AFARTNLAVLGPHTYRAGASSMFGMANYPWLQVPSATALLDLWQKVGVNRVRIAYDGGP
                     GLPPSAFDARGMRHNIELQPTLDVTDEVAARWAAANTDKAIAAGADYFEVGNELNRPFN
                     TGVAAQAYIDKALRPVRDRLTATGSGLKLLNNGLAGMDEPWVENFIAGGGWDLIDGFAY
                     HPGRGNVTPDHIPAPGDWDAGAHGAYWNFLGGLRKLQALMAQHGRKDIWLTEAYACTRP
                     NAWWNDTYRQAAENVFLTLAIAKAEGITGVLWYQFHDSVLGMPQVADPGNVEYHFGLMN
                     RDISPKPSLLAYATAARAFDEATPLGWLAFPDPQTKGLLFDTPDGQAAVLWNRADGYTL
                     NTGHDPAGWHFPAPEVWVDHWPTKTPMTVPTTGATLRQLDCIGRPTTIQAPGNRATVVL
                     DGAPRLFTGVDLTTALAD"
     misc_feature    complement(19992..20007)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.5"
                     /tool="antismash"
     misc_feature    19995..20008
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.01"
                     /tool="antismash"
     misc_feature    complement(20074..20087)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.23"
                     /tool="antismash"
     gene            20141..21184
                     /locus_tag="HNR73_RS28305"
                     /old_locus_tag="HNR73_005779"
     CDS             20141..21184
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012742.5"
                     /locus_tag="HNR73_RS28305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005779"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_184790709.1"
                     /transl_table=11
                     /translation="MTARPGKVTQREIARIAGVSQTVVSMVLNDRDDTNVRIPAATRER
                     VRRAIEQSTYVADPAARRLAGLDNKILGVFTYESALTPESMDFYGPLLNGIERAAERLG
                     CDLLFFTGSPVEEGRRRLFHRDTRLRLADGCVLLGQQMDGEDLERLVAESFPFVAVGRR
                     DETDADVPYVGIDYGALTATLITRAAELGHRRAVYVHRDRDSPTARDRLAAITTSTGQV
                     AFTLTAVGDDLTGLPGIITAQGATAVFAEDAFLVEDIALVLSEAGITAPAQVSLAALGE
                     VRGHRIAERPLTGFQVPRQQIAAEALALLQQLISTPADEQAAITRQRLLQGDVEYGGTL
                     VARGGAR"
     misc_feature    21622..21635
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.64"
                     /tool="antismash"
     misc_feature    21656..21670
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 gtcccggcgg gtggttcggc gatgagcggg agggtggccg cggtgtagcc ggtgaactgc
       61 tccagcggaa cgttgatgtg cggcttgatc cacccgaggt agcggtcgta gacggcctgg
      121 gagaccggcg ggaggccggg cagtccgacg ggactgttgt tcgcggcgtt cgactcggcg
      181 tcggcgaggg cggcggcctg gtcgtagtac ttgtcgaagt cgtagaactt gatccacttg
      241 gcggcggcca gcagctggtt cggggtcgcc ttggcgtcga agagtttcag ggtcccgccg
      301 gtgagggtgc cgttgccgcc ggcgccaccc tgcgggagcg cgccctggcc gtagtcggcc
      361 gggtcgaagc cgtagtcctt cacgacggtg aagtagcagt cgggtgcctg caggaccatg
      421 ccgatggtgc caccggcgaa ggcctgccgc acggcctcct ggtcgtagag gaactcccgg
      481 cccatcgtgt cgtcacccca gcgcatgtcg tgcaggagct ggagggcgtc gatggtctgc
      541 tggcccatga cggcctcggt gccggcgtcg ttctggacgc ggccgccgag ggagtaggtc
      601 atggtggtca gcatccagcc accggtgttg ttggtggtca tctgcgcgta cggggtcaca
      661 ccgccgacct tggccttgat ctgccgcgcg aaggcgcgca cgtcctccca ggtggccggc
      721 ggcgtgtcgg ggtcgagacc ggccttggcg aagatcgcgc ggttgtaggc gatgccgacc
      781 gagaacaggc cggtcgggat cgtgtagatc ttcccgccgt cgtctttggc gttgtcgagg
      841 gcgagcgggt tgagatcggc gacgaggccg agctcgtcga ggtagggcgt catgtcgggc
      901 agctggccgt tctcgatcag ctcgtggctg taggtcagcg agacgcccat gacggtgggg
      961 agggtgccgc cggcgagttt ggcctggaag gtctgggcct cccacttctc cggcgaagcc
     1021 tccacggcga tgttctggtt ggcggccttg aactcttcga tgcgcttgtt gaaggcggcg
     1081 agctggtcgg gcttgtcctc ggtgggctga tcgccgaccg atatcgagac cttcgccgag
     1141 gggtcgaggg cctcggtggc ggcgtcgccg ccggggtcgc tgcacccggc ggtggccatg
     1201 gcggccgcgc cgacggatcc ggccacgagc acctgccgtc gtgacagttt cggcattgaa
     1261 actcctgggg tggtgaggag cgaaacaggg ggtggtgggt gggggagtcc cgtgggggcg
     1321 ggacgtgaag acgtgtagac aaaataaaac catgagtgtt actaaatcaa tggcacagca
     1381 acctaaagtt caaaaacgcc ccacccccga cgaggagccc accccacatg aacccccacc
     1441 caccactgcg cctggccgtc gtcggctgcg gcgtcatcgg acgcctccac gccgaactcg
     1501 ccgcccacag cccagacctc cacgtcgccg ccctcatcga cccctcgtcc gccgccacca
     1561 ccgccgtcgc cgaacacctc caccgactcg gagccccacc accccgcgtc cacaccgacc
     1621 tgacgaccgc cctcgccgac ggcggcatcg acatcgtcgt gatctgcacc ctcagcggca
     1681 cacacgccca actcggactc gaagcgctcg aagcgggcct ccacgtcgtc atcgaaaaac
     1741 ccctcgacgt cgacgtcgcc gccgcacggc acctgcgcga tgccgccgct caacgccccg
     1801 gccaagtcat cgccgtcatt tcccagcacc gccacgaccc ctccgcccgg gccgtccgcc
     1861 gcgccctcga cgcacgacgc ttcggccgga tcacctcggc ggtggccaac accgactggt
     1921 tccgcagcca ggagtactac gactccgccg cctggcgcgg cacctgggcc ctcgacggcg
     1981 gcgccctcat gaaccagggc gtgcacaccc tcgacctgct cctgtggttc ctcggcgaac
     2041 ccgtcgacgt caccgcccac accgcccgcc tcgcccacga acgcatcgag gtcgaagacg
     2101 tcgccgtggc gatcctgcgc ttcgaagacg gcgccctggc caccctccac gccaccaccg
     2161 ccgcctaccc cgacctcggc gtccgcctgc agatccacgg gaccgacggc tcggcggtca
     2221 tcgccagaga cgaactgacc ttcttccaca cacgcgacgc cgaagacatc gacggcgacc
     2281 aggtcacccg cgaactcgcc gaactcaacg gcggtcccgg caactcccac caggcacagt
     2341 ggaccgacat cgtcacggcg atccgcgaag gccgcacacc cctggtcgac gtggacgccg
     2401 gattcctcgc gctgaccacg gttcgcgccg tctacctgtc ggcgacgctc gggcgcacga
     2461 tccgggtcgc cgacgtggcc gacggcaaat acgacggaca ggccacgcgg accggatccc
     2521 agacctgagt tccaccgcga cgccgagaac cccgtggcgg cagccgaacc ggctcgcccc
     2581 agccgacagc ggtcggaatg tggcgcggct gtggccgttg tgtggcgcac cgttgaacca
     2641 tggcgatgcg gcaggggaga accgccgcag gcgggggaca gggggttaga cgtcccccgc
     2701 gccacgcaca cgcatgggga gaatcacagt gcgcaaacgg atcatcacgt tcatcgccct
     2761 cgccttcgcg gtcttcgggc tgctgggctc gacggcggcg tcggcgagcg agaccggatc
     2821 ggagcccgcg ggggtttcga gcctgaccga gctgaagtcc ggccaggtcg ggacgctggc
     2881 cagcgaggag atcgactacg cggtcgagca cgccctcacc gatcccacga agtactgcgc
     2941 gggcaacggt tacgtctcgg gctgcgtcca gccttacggc gacgtcctgt ggatcaagga
     3001 caacgcgtcg aacggggccc acgtgacgct gaagtgggag gacctggacg gcgaccgcta
     3061 cggcaagtgc cgcaacacgc tcggcgcgga cgccggatgg gcacgctgca acaaggatct
     3121 gccggagaac caccggatcg cctggcagct ggcgtacaag gtgagcagcg gcagcgactg
     3181 gtcgtacagc ccggtctacg agaccagggt ctaggcgtcg cgaccgtctg aaccaccgcg
     3241 ccgacggccc gccgggtacc cgcccggcgg gccgtcggcg cgggctttgg tgctggcgtc
     3301 gaggatcgcg cgggcctgtg ccggcgaggg cgccggacac tagcgcacgt tgctccccgc
     3361 cgacccggcc gcgggcggca ccaccacgac cgttcccgac gagaccgcca ccgacgccgc
     3421 ggtgtacccc acgagctggt tgtggatggc cgtgttgacc gtccccgcgc ccgcccccgc
     3481 cgagatcgcc acgactcctg ctgacacgcc ccgcacaatc gtgttccccg aggccatgca
     3541 gaaggtcgcg ccggtgccga aacggagccc ggcggtagcg gcggcctcga cgcggttgcc
     3601 ggtcacggcc gtggcgttgg tcgccgacag gtagatcccg tagttcgtcg cggtgtcgcg
     3661 gatggtgttg tcggcgacga tgacgccgtc ggtgtcggtg acgttcacgg cgttcgacgc
     3721 cgtcgaggcg atgacgttgc ccgacacgat gccgcccgcg cccagttcga cgaggacccc
     3781 gttggtgccc gcgccggtga tggtgttccc gcgaatgacc ggatcacgcc aggcatgcgc
     3841 ccgcaccccg tacttcaggg cgccctcgca gacgttgtcg aggatccgga tcccgtcgta
     3901 cacgcggtcg tcgacgtggg tgtgcgatcc ggcgagcgcc ccgaaaggcc cgagaccggt
     3961 tccggcgctc gggtcgtagt cgagggaggg gccggcgtag caggcgcgga cggtgacgtc
     4021 gcgcgaatgc gtcccgtccc actctccgag gtcgctgctg gcggggctcg cggcgacgtc
     4081 gatctggaag gcctcggaga agacccggtg ggccaggctg agcaggaagc cccgcgcggt
     4141 cacgttgtcg atcagggcgc cgtcgcaggc gttgacctcg accgcgtgat acgacgcgac
     4201 attgcggatc tccaggtcgc ggacgacgat ccgccgccct ttcgcgaagg tcatggcgtt
     4261 ccacgccgca ccggcgtgcg ggccctcggg cgcggcgagt tccccacggg cgtcccagat
     4321 cccgccttcg agggtgatgt cgccgtgccc gtcgtggccg gtgaaggagt cctcgggggc
     4381 gaagttgcgg atgaggctgt ggccgccgga cccgccgacg cgggcaccgt gcgcgtcgag
     4441 gcgggtcccg gtgcgtaaga ccagcggcgc cgagatgcgg atcttcgccc ccgcgatcga
     4501 gctggaaccc ggtccggcgt cgagcatcag ctggacggct gcggtgtcgt cggcgacgcc
     4561 gtcgaggacg gcaccgtaga cggggtcgga aatgtggcgc atggacggcc cccgatctcg
     4621 gtcggcgcga tgcacaggcc agcgtagtcc cacctcaggc ccggcggcgg actttcacgg
     4681 tcacaccagg cgagtgcatt cgtcctatgt ggaggcccca cggttcacgg cgccgtggcg
     4741 agcccggcgt agaggtagac accgggctgg gaagggtcgc cgacgagcag cacctggtca
     4801 ccggcccggg ggatctgcag cttcgagatg atggtctgca gcccgatgcg gccgacggct
     4861 ccgggcgcgt cgaggaccag gtcgacgatc ggttcgaagt tgaccagctt gccggtgtcg
     4921 ccgatcgaga cgacggtcgc cggaaacgtc ggcacaccgg cggccagcaa ctgctggacg
     4981 taggcgccgg agttgtgcgc ggcgatcgac tgctgcacct tgctgaagtc cgcctcaccg
     5041 aggaaagcgc gcgtcagccc gccgtagaag cccttgccac tggcgacctt gccgacgatc
     5101 tcggcgttgc gctcctcgcg gctcttgcgt ccgaagaatc ccatgatgtg cttcccttcg
     5161 atccatgtcg tcgatgactg acgacatgga cgttagggcg ccacgggcgt ctaccggtcc
     5221 caggttcagt gcgggtggag gtgctgacct gcctgcgggc tccggtgccg ggccgaacat
     5281 cgaagggctc cagctcaggc aggcgcagcc cggttccccg agagtccgca acggctacga
     5341 agcccgcacg accacccacg aaagccggga gcgcacctga gcacggcgac cgcgaggggc
     5401 ggcgtgggcg ggcactcgtc accgcgacca cgatgccggg tgtccgccct cgccgggacc
     5461 gcctcagatg atgatgcgct gggccttgcc aaggcgccat tcgccgtccg cccaccagct
     5521 ggtggtccac ttgatctcgt gcccgtcggg caggtccttg tcgcagcgcg tccagtcccc
     5581 atagccctcg gcgtcctggc agatgccgcg ccggggatcc tcgggatcgg agttgtcgat
     5641 ccacaccagc cgcacatcga tgccgtccca ctcgtcgtcg cgcagccaga gcatgtcgcc
     5701 gtacggctgg acacagccct tgacgtaggc gttgtcgagg cagttcctgg gcgcatcggt
     5761 caggtcgtgc agtttggccc agttcttctc cagcggcctc tcttcgttcc ccgccgcggt
     5821 gtcctcaccg gcggagcccg gaccgcgcgg tgcggccgcg gacgccgtgc cgggaatgag
     5881 cagggcgctc gccgtagcga gaacggccgc cgccacggtg tacttcgtga tgcccgaacg
     5941 catgttgccc ccatgtgccg tgttggtttc cggtcggtgc gtccgatgcc gagtcggtga
     6001 acgcccctac ccatgaaggg ggctgcgggc acctgagggc gcgtgttcgg ccggaatgtg
     6061 gccagaactg gccggatatc gcgcgttcgg cgcacctggc gggccccggc ggtgggcgcc
     6121 gggacccgcc acacgttcag accagcgagc gtgtgaggtc gcgcgaccag cgggcgatgc
     6181 ggatgacgtc ggcacgcagg tcgccccagg tgacatgggc gttgtacagc gcgcggaact
     6241 cgaatggcac catcgggtgg ccgacgatgg agttgtccac gccggtctgg ttcatgccgc
     6301 cgaagagcac ctcctggctg atcccgttct gcccgttgag gccggaggtg atgtaggtga
     6361 ccagcgacgt ggtcccggcg gtggggctgg tgagctggta gttgtcgggg aagtcgatgc
     6421 cgtgcgcgtt ctcgaccttc gcggccaagg cgttgagcac ggggtcgacg ttgccgctga
     6481 gcacctgacg cgaacccgcc gacagcacgc cccacatctg cgcgagggtg gccctcggca
     6541 gcgcggcgat cttgttcttg acctggccgt ccccgaaggg gagctgggcg agcacctggt
     6601 tgagtttcgc gtgattgacc ggaaccgccg tctggaggtc gttgcgctgg ttggccagca
     6661 tgcggtcgat ccacaccatc gcgtgcatgt agagcagcgc gaggtgaccg cgcagttcgg
     6721 tgcgcacggt ggcggcctgg gccccggtgg cgccgatggc gacgttcagg gtgttgttca
     6781 cgatcgtgtc ggcgacggcg atgccgttcg tcaggtgtgt tcgcgagcgg acgttggcgc
     6841 tgtcggggcg ggtggccggc gcgatgccgt tgagcatcgc gcgccactgc gcgggggcga
     6901 atccgacggt gtagtggatg tgcagcaacc cctggtcgac accggcggcc ggacagttgc
     6961 gcacgttgag gttgccggtg ttgccgtaga cgggatcgat gtagaactgg atcgcctgat
     7021 tgcccggctg cgggtcggtc agcaggttga ccagctggtt ctgggcggcg tacagctcgt
     7081 cgttcatcag catcagcgcg gcgacccgtt cgccgaccag gtcggcggcg ttctggtcgg
     7141 taccggcgag ctggtcgacg tggcggacga cgtactccat gttggagtac tggccgttgc
     7201 cggcgttgac cttgtcgctg accagccgaa accagggatg gctcacgagc ttggtgtcgc
     7261 cggtcaggac ggtgttgttg ttgtcggtga tctttcgcag gatttcggct tcgaaaccta
     7321 aggccatggt cccctccgcg tttctttcct tcgacgctag atgtcactta ccgcgatcat
     7381 ccaggtacga agggcagttt cgcgtgcctg tgggcgcagg ctcgaagcaa cgcgagggca
     7441 accgtccctt gtggacttac agcatctgtc gcgtccggcg aagcagtgcc caggccaccg
     7501 tccagtaccc ggcggccgcg gcgacggcga ggccggcgag ccacggccag gcggcggaga
     7561 agccgacgat ggtcgcgtcg cgcaggccgc gcaggccgta ggtgaccggg ttgaccgtcg
     7621 agatccagcg caggaccgtc ggcatgctct cctcggagta gaacgacggg ctgctgaaca
     7681 gcaggaccgg caccgagagg ttgacgacga tgttgaaact ctggaagtcg cggatgtagg
     7741 cgcccagcag catgtacagc gcgttgaacg ccgccgacac caccagcgtc gccagcagca
     7801 gcgccagcca gttctccgcc gtcagcggga aacggaacag cagcgtcccg acccccagcg
     7861 ccaggaacgc ctgcaccagc accagcgcga cgctggcgat gagtttcccg gcgatgtagc
     7921 tgaagcgccg caacggatag gaccacagcg ccagcgccat cttgctggcg tcctcctgga
     7981 acagcgccgt cccggagttc gccgaggcgc tgagcaccgc cgtcatcagc accgtcggca
     8041 gcgcgaacac cagataggac acctcggtgc cggcgtaccc gaccaccgag atcatgttgc
     8101 tcagcgaggt gctcagcagc agcaggtaga tgaaaccgtg cacggtcgac agcacgaggt
     8161 tgacccggtt gcgggtcagc agcatgaact cgcggtacag caccgccttg aggtcggcga
     8221 ggcgaccgtg ccgggcccgc gactgcggtg ctccggacag cgagagggtg gtcatcgcga
     8281 ctccttgacg gtcagcgcca cgaaggcgtc ctccagcgag gcggcgaaca ccgacacccc
     8341 cgccagttcg atgtgctcat cgtgggcgaa gcgcaccagc tcgggcatgc gctcccgggc
     8401 gtccttgccg gtgatctcga cacccagctc gtcggcctcg ccgttcaggc cgcgctcggt
     8461 ggcccaggcc agcagcgacg cggcgtgtgc ggggtcggtg agttcggcgc gcacaccact
     8521 cgatccgaac tccgcggcga tggcggccgg atcggcgtcg cgcagcagcc tgcccttgtg
     8581 cagcaggagg atccgctcgc agttgcgttc gatctcctcg atgtagtggc tggtccacaa
     8641 gacgctgacg gcgtactccg cgcgcagttt ggccaccgtc tcccacacct ggcggcggcc
     8701 gctgacgtcg aggccggtgg tgggttcgtc gaggaccagg accttcggca gcgtgatgag
     8761 cgcccggacg agctggaggc gctgccgctg cccgccggag agctggaagg cgggcttcct
     8821 gaccgccggg gtgagttcga acaggtccag gagctcggcg acccagtcct tgacctcgcg
     8881 ccagcgccgg tcggcgaagc gggcgccgat cttgaggttg tcgacgacgt tgagcatcag
     8941 gtcgaagggc gccgactggt gcatcacgcc gagggcggac ttggcggtca cggggtctgt
     9001 caccgggtcg gcgccgaaga cccgcaggga accggagctg gccgtggtga ccccgcagat
     9061 cagcttgatg aggctggtct tcccggcacc gttgggaccg agcagtccga tgacctcgcc
     9121 ttcggcgacg cggaaggaca cgtcgtcgac ggccgggacg tcggagcccg ggtaggtctt
     9181 cgacaggtgc tcggtctcga tcacgacggt catcgcggcc gccttcccgc gggtccggcg
     9241 gggaccggcg acagttgggg gacaagggtt tcggtgaccc acgcggtcgt cggccactcg
     9301 ccgaggggcg cggtacgcac gaagacgtgg gcgaggtcct cgggcagcag gacggtcccg
     9361 tcggccagtg gtggggcggc ggtggtgaaa ccgacgccgg tgacgacgtc gacggttccg
     9421 tacgcggtga ggtcgagggc ggtgagcagt tcgatgccgt ctcgggccga ctggcagacc
     9481 cctatccgca ggtccgatcc ggtggtctcg gcgcggagcc gttcgacgac gccgggatcg
     9541 gcgccgatgc cggcgcgggg aagccgtgtc acggtcaggc cgtcggtgtc ggtcgtcgac
     9601 caggtcgcgc cgtgctcgaa cacccacagg cgtaccgccg ccggtccggc gcccgtgggc
     9661 gccggaacca gcttcatcgg cgaaggcgcg gtgaaaggcg cgagcccttc gacgacgccg
     9721 aggaagtccc cgcggtgcgc ggccgggtcg accctgcggc gggcgtcccc ggccgtgaac
     9781 agccggtctg cgtcgcggtg gacgacccgg tgcaccacga tgtcctcgcc ggccaggtag
     9841 gccgcgacgt cgccgaccac cacgttctcg aagcggcggg cggtcagcgt gacccgggcg
     9901 ggcgcgacga tcgtcggggc catgctggtg ccggccacgt cgatcacggc ccggccgagg
     9961 cgcgccagcg cccgccggac gagcgcggcg gcggccgccg tcacggcgcc gcggcggtgg
    10021 ccggagacac cacgcctcgg gtggccaggt cggcgaggaa ggcgtgcacg tcctcggcga
    10081 tcagcttccg ctcggcctcg tcgtcctcgc cgtacaggct cgacaggcgc gcggcgatct
    10141 cctcggtgcc gaggccttcg acgaccagtt cccagatggc cgtgcccgag gcgttgaggg
    10201 tctggaaggt cccttcgagt gcgtcgtaca gccggatctc cccgctgtcg gcgctccaga
    10261 cgatctgctc ggcgatgatc cacgggttcg acatcagcgg gcctccacga tgttcagcag
    10321 ccgccgggac ggggtctgcg gcgaggcggg cggcgtggcg gcgagttcgg tgcgccagtc
    10381 ctcgtagacc gggtgcacct cgccgttgcg ggccaggcgc ggctggaagg cctcgctgtc
    10441 gccgacgagg gtgtcgccgg aggcgccgag actgtgccag atcgagctga tcttctggtg
    10501 gcgcaggatg cggcacagct gccgggagtt cttgcgcagg tcgcccgact gggccaggtg
    10561 gtaggcgcgg cagccgccgc cacaggcgcc cttgatgtag cagcgctcgc agtcggtgtg
    10621 caccgtgccg ccgaagatgg tgctgttctg gaattcggcg aacagttcac cgttgaagat
    10681 ctcccgcagc gaggaggcct tgacatttcc ggcgaggtct ttggggctgg tgaccagctt
    10741 gcacgggtat accgcgccga gggaattgac gtagatctcg ttgctgccca ttccgcagtt
    10801 ggcgcggaca ttgcacggct tttccggggt gacgtggtcg ggcagcatgt tcttggcctt
    10861 ggggtgggtc caggcgaaat cgtggatctt catgtactcg ccccagccga atgacaggtc
    10921 gtcgccttgg ccgcggccga gatcgctgtg ctgcatcatc cgtacgcgct ggagtttgaa
    10981 ctggccggcg aagtcggcga agtcttcgag gtactgcacg ttgtcattgg tgacgacgtg
    11041 gttgatcatc gggacgactc cggcgtcgtt gagcagccgc aggccggtgc tggtcttggc
    11101 gaaggttcct ctgccgcggg tcttctcgtg ctgttcggcg gtcgctccgt ccatgctgac
    11161 ggtcaccatg tcgaacagtt ctgacatcgt ctcagcggtc ttcgcgttac gtatgagcgt
    11221 gccgttggtg atgatgttgg tgcgcattcc cagtgagcgg gcgtggcgta cgacgtcgaa
    11281 gaggtcacgt cgcatcatcg gctcgccgcc ggtgaagacc atggtcccgg cgcccagttc
    11341 ggcggcctgt tcgaccagcc gcagggactc ctcgtggctc agttcgccgg gcagtgcctt
    11401 ctcggaggag gcgtagcagt aggggcagcg caggttgcag ccgtcggtga tggcgtagta
    11461 gacgatccgc agttcgacga cgtgctcgct gcgttgcggt tcgtgcccgg gcaggtaggc
    11521 caggaagttg acgaccagct gcgcgaggtc cttctccagg gccagcccga agtcgtcggg
    11581 gtggaagaag gcgagatcgc ggcgggccag cgcgcacagg atctcgtctt ggcggggcgt
    11641 gagccggccc caggccgcca gggtcgggtt gagggcgaac cggtcgccgt tcgccgcgcg
    11701 gaagaccacg atgtcgtcgg gcacgaccag cgcgtccaac tgaccggaaa tgagcatggg
    11761 caattcaccc tctccacaag aagccgtaaa tcctttttgc gagcaggcgt atcgggtgat
    11821 acgcctgccg agactcgtcg agtctgaatg gttcgggccg gctttagccc gcgccgcttc
    11881 cggagagcgc gccgcaggcg caggcgcact tgtcgatgat caaggcgccg gtgaccgact
    11941 ccttgcgcag ttccggcttg gcccacttgc gagacaccgt ctcgttcata gttccagccc
    12001 ttcctactag tacggaggtt tcacctccgg ttgatgggct agaagttacc gatcgtgatg
    12061 ttgcgtaaac aagggaaaag aatcgaacat tatcgttccg tgatctgatc atgaccgttt
    12121 gaaaaggttc gatcattgcc cttaagggag tattcgcagg acgatcgcac gtcggcgcgc
    12181 agtcgcctgc tgccctttcg gacactccgg ccccgcaaaa agaatgtgcc aacttcaccg
    12241 cgaagaacac gctttatcgg acaatcgctg cgtaacctcg acttaaccgc tgtgtcgaga
    12301 tcctttacgc cttatccgtg gaagccgcgc aatcgccgcc gcgaattctc ggatgcgcaa
    12361 gacccgttcc accgccgaaa cgtgcacgcc gaacccttga cgcgccgacc gtcgggccgg
    12421 tagtcgcggc gggtgggcgt ggcggctccg cttgcggggg aagacccgtc cccccaacga
    12481 cgcgcgtcga ggcggcgcgc tcactccacc accggcaggc tgatcgcatc cggttgccgg
    12541 gggtgctccg acgccccaag gctctctcgc tcgtctgcgg tgatggcacc gaaccggtgc
    12601 agtacgtcca gtgaaacgcc ccagctggcc agtgcctcgc cgactcgccc catcgcgtac
    12661 agggcctcgg ccaggcccca ggcatagtcg gcggccacga gggcctcctc ctgcccggct
    12721 tcgcggttca tcacgatggc gtggccgtag tgctcggcgg cctcccggta gttcccgagt
    12781 tccatgtgaa tgcccgccac cgacgatgac gtgagggctt gcccgtgcgg actgcccagg
    12841 cgctcggcga tcgcctgggc acgctgttgg gcgtcgaggg cggcgggaag gtcccccacc
    12901 tgccgcaaca gatgacccat cgcgttcagg gtggcgcctt cggtctgttc gagcccgcac
    12961 tcgcgggcca gttcgaccga ccgcgcgtag gcgtccaggg cttcggcgtg acggtcgagg
    13021 aggctgtggg cgccatcggt gagaccgagc agaatcgcct cggtgtgccg gtcggccatc
    13081 aggcgcgccg cctcccgggc gacggcgaga tgagggaggg cctcgtcggc acgttcactc
    13141 gccaccagga cctcggccag atctcgatgc gcgacgagca tcagctcccg atctccgacg
    13201 gactcggcga tggccagggc ctggtcgccg atctcacgca gagccggaag ttccttgatg
    13261 tagtcgagtg gagtcgtcag caggtgcgcc agcgtcgtcg cggtctcgtc gccgagaagc
    13321 accgcctgcc gcatgacggc gcgcaggttg tccaactcac cctgaaccca gcgcgtcgcg
    13381 gccgtgcggt cggacggggg agtgcccgca cgctcgctcg gcccgacgcg gtactcgcgt
    13441 cggaccgtcg cccgcggctc gatcacgccg atggtggcgc gcgcggcgcc gacgtagtac
    13501 ccgaggatcc gcgtgaaacc gcccgcggct tccgcgggcg acaggggctg ctctttggcg
    13561 aacagacgca tcaggtcgtg caggtggaag cggtccccgg actgctccag gagctgcgcg
    13621 tcgacgagcc cggccagcag gccctcggcc tcccgctcgc cgacgtcggc cagtgccgcg
    13681 gcggccggaa cggacatgtc gggagtatcg accgcaccga gcaggccgaa caggcgaagg
    13741 gccgggccac cgcccatgtc atcggccagc tcagcgaggc tgacggcgaa gctggcgcgt
    13801 acggcgcggt cgtcgacggc gagctcgccg aggcgggcgt cctcagcggc gagccgggcc
    13861 gcgagtgcgg acagtggcat ggtcggccgg gcccgcagac gggcggccgc gatgaccagt
    13921 gcgagaggga gtccaccgca gtggccggcg atgtcggcgg cggcctcggt ttcggcggcg
    13981 acgcgctcga tgccaaggag tctggccagg acgccgatgg cttcggcatc cggtagggcc
    14041 tcaaggcggt ggatcgtggc ctcgtcgagc gtcgacagga cgcggcggga ggtgatcacg
    14101 accgcgcagg cggggccacc gggcaggagc ggccggactt gggccgcgtc gcgtgcgtcg
    14161 tctagaacga tgagcaggcg tttccctgcg gtcgccgaac ggaagcgccc ggccagttcc
    14221 tccacgccga gggctgaagc cgaagccggg ccttgcaggg agcgcaggaa ccgcctgagg
    14281 gcttcttcgg gctggagggc tttcacatcc ggtgttgttc cgtgcaggtc gacgtagagc
    14341 tgcccgtcgg gaaactcccg cgcgaggtga tgggcgatgt gcagcgcgat cgccgacttc
    14401 ccgatcccgc cgggcccggc gatcgcgcag acggccccgg gtgcggcgaa gacgtccagg
    14461 acggcggcga cgtcgtcggc gcggccggtg aaggtgcgcg gtgcggcggg cagttcggcg
    14521 ggtcctgacg tcgcggcggc gggttcgggg ccggcctcgt cggtgaggac ttccttctcg
    14581 gcccttctca gccgtggacc gggttcgaga ccgagttcgg cgacgaggat cgcgcggcct
    14641 tcgcggtagg cctccagtgc gtcggcgcgt cggccgcagc gatggagggc gagcatgagg
    14701 ttggcgcgga tgccctcgtc gagcgggtgg gccgccgaca acgccgtcag ttcgggcagg
    14761 agcgcctcgt gccggcccaa ggtgagatcg gccgtgacgc ggtgggcgag tacgtccagc
    14821 cggagtcgct ccagccgggc cgcctcaccc tcggggatgg cgtgttcggg tacgtcggcg
    14881 tatgcctcgc cgcgccacag acccagcgcc tcggcgaaca gggcgcccgc gtgggcggtg
    14941 tctccggcac gttgggcggc caggcccgcc tcgcgcaggg tggtgaagca cgaagcgtcc
    15001 acttcagtgg cttcggcggc caagacgtag cccgtctgcc gccagacgag ccggtcaggc
    15061 cggtcgagga gtttgcggag ctgcctgatg tgccaggtga gcgcccggcg cggggaggtc
    15121 ggcaggcgtc cgccccataa gccctcgtag agggtggcgg gtgaggcggg ccggccggcg
    15181 cgggagatca gcgcggccag cagcgcacgc tgctttggac cgtcgatgtg cgcggtgacc
    15241 ccttcggtct gaagccgcag tggaccgaga acctcgaaac gcatgtgacc ccccaggaca
    15301 tgtcttcgcc cgacagtcca ctatgcccgg tgcgcgcacg ctcgcctcac cgcgacctca
    15361 ccgtcgcctc accggtcgct cgtagcgtcg ccatacgaac gagccggccg tcgcacccgg
    15421 aggggaggcc gcgaagacgc cggatggctc ggtgtacgag gcttccgcgc tgaagagacg
    15481 tcgcggatga accgttgact gagtcgggac aggccgtccc gactggagga ggaccagtgt
    15541 tacgacgtat gaagcggacg ctgtcgatca cgttgctggc ggtactggcg atgggtgctg
    15601 tgtcgtcgcc ggtgtacgcg tcggcggatg gactgacggt cgcgagccaa ggggcgggcg
    15661 tgggtacgcc gggaggtgcg gactcggcgc tcgcggcctg taccaaccgg atcaccaggt
    15721 tcggatactc cggctgcatg agcgatggca cccagcccgc ggactgtccg tgggacgagt
    15781 cgttcgtcat cgcacccgac cgcacgatct ggcacgcctg gccgcgaagc ggtggctgga
    15841 aggagatgcc gaactacggc aaggccgact tcgccacgaa ctgctactac aacggcaaca
    15901 acaagcacca gatcgacgtc tgggttcaat acacgggcgc ctactactac tcgtatcaca
    15961 gcggtggtgc ctggcacggc tggtacagga actgacgtcg cactccggcg gggcgcggcc
    16021 tccaagggcc gcgccccgcc gcgcagcgcg gaagcggtaa gtaccggggc acgtctttcc
    16081 cgacgacgcc gtcgaactgg gcgcggcggg cggtgtcggc agcgcgcggg gcttgtcgcg
    16141 catgtactcc tggctgctcg acgcgttcga gccgggcacc gtcgccgaca tcccgcgccc
    16201 ggagacgagc ggaagcgacc tcgtaccgtc cagcccggcg atgtcggtgg agcagcgttt
    16261 cggacgaggc ttcatggtgc cctcggcgga ggagacgccg gcgaggtcgg cgaccttcgg
    16321 ccacgagggc gccggaggca cgaccgcctt cgccgatccg ggcggcggtc tcgcgttcgc
    16381 gtatgcgacc acccggatcg cgctcggccc gccggatacc gatccacgcg ccgaggcact
    16441 gatcacatcg gtgtaccagg ccttgaggac gggttgaacg agccgaggaa accgtgatcg
    16501 gtgccgcacc ggccgagcct cggtagcggc ctctgcgggc cttttctcgc cgtaggcgcg
    16561 ggaggcaccg cctggccggg tgtgaccccg gccacgccgg tggatcatcc ggtcgtggga
    16621 ggcgcctgga ccgtccggcc ggactgtgcc cggcgcgcgg cccgttccct cagtggataa
    16681 gacctgctcg tccggtattg aaccgaatgt cgcgggtgtt ctggctaggt ttcctgacgt
    16741 tatgcctcga tacctcatgc acctggcgag gaaggccgtc gacggcaccg gcgagtacgt
    16801 cggccgtgtc acgcccgtcc tccgtaagcg tctgtccggt ctcagcgccc tcgtggcgcg
    16861 ttcggcacgt gtggcggctc cggtcgtcgt cggtgtccga cgccgcttcc cgcggttgtc
    16921 gggcgcgctg gaaacctctg tgccgcgggt cggtctcgcc gcggcgatgc tcacggcgat
    16981 cctcctggtc gtcttcatgg cgaacttcgc cggcgccatc accggcggca ccccctcgga
    17041 cgcctcggcc gccgtcggtg cgcgcgggac gcaggaggac cagtcctccc gcgaccagga
    17101 gcgcggcacc gagcccgccg agaagccccg ccccaccaaa ccggtgaagg ccaagagcgg
    17161 ctgggccgcg ccttcgacgg ccgagctcag cgaccactac ggtccccgcg ggtggcgcga
    17221 cggggaaatg cactggggca tggacttcgc cgccgacaag ggcgacaaga tctacgccgc
    17281 cttcaacggc accgtcgtca tggcccagcg ctacggcggt tacggcaact gtgtcgtcat
    17341 caagcacgcc ggtggtgttc agaccctcta cggccacttc tcgaagctcg acgtgagcgc
    17401 cggcgacgag gtcaagaccg gcgatctcct cggccgtgcc ggctccaccg gcgacagcac
    17461 gggcccgcac ctgcacttcg aggtgacggt gaacggctcg tacctggacc cggagaagtt
    17521 cctggagaag aagggcgtcg acttctaggt cgcgcccccg cgatcgcccg cgaatgcggg
    17581 cgatcgcgcg aagcggtcag tcggccagcg cggtcgtgag gtcgacgccg gtgaacagcc
    17641 ggggcgcgcc gtcgaggacg acggtcgccc gattgccggg ggcctggatg gtggtgggcc
    17701 ggccgatgca gtcgagttgc cggagcgtcg cccccgtcgt gggcacggtc atcggtgtct
    17761 tggtgggcca gtggtcgacc cagacctcgg gggccgggaa gtgccagccg gccgggtcgt
    17821 ggccggtgtt gagggtgtag ccgtcggcgc ggttccacaa gacggcggcc tgaccgtcgg
    17881 gggtgtcgaa cagcagtcct ttcgtctggg ggtcggggaa cgccagccag cccaggggag
    17941 tggcctcgtc gaaggcccgg gcggcggtgg cgtaggccag cagcgagggc ttggggctga
    18001 tgtcgcggtt catgagcccg aagtggtatt cgacgttgcc ggggtcggcg acctgcggca
    18061 tcccgagcac gctgtcgtgg aactggtacc acagcacgcc tgtgatccct tcggccttgg
    18121 cgatcgccaa ggtgaggaag acgttctcgg cggcctgccg gtaggtgtcg ttccaccagg
    18181 cgttgggccg ggtgcaggcg taggcctcgg tgagccagat gtccttgcgg ccgtgctggg
    18241 ccatgagggc ctggagtttg cggagcccgc cgaggaagtt ccagtaggcg ccgtgcgcgc
    18301 cggcgtccca gtcgccgggg gcggggatgt ggtcgggggt gacgttgccg cgtccggggt
    18361 ggtaggcgaa gccgtcgatg aggtcccagc cgccgccggc gatgaagttc tcgacccagg
    18421 gctcgtccat gccggccagg ccgttgttga gcagtttcag gccggatccg gtggcggtga
    18481 ggcgatcgcg gaccggtcgc agtgccttgt cgatgtaggc ctgtgcggcc acgccggtgt
    18541 tgaagggccg gttgagttcg ttgccgacct cgaagtagtc ggctccggcg gcgatggcct
    18601 tgtcggtgtt ggccgcggcc catcgcgcgg cgacctcgtc ggtgacgtcg agggtgggct
    18661 ggagttcgat gttgtggcgc atcccgcggg cgtcgaaggc cgacgggggc agtcctggcc
    18721 cgccgtcgta ggcgatgcgg acccggttga cgccgacctt ctgccacagg tcgagcagcg
    18781 cggtggccga ggggacctgg agccaggggt agttggccat cccgaacatg ctcgacgcgc
    18841 cggcccggta ggtgtggggc ccgaggacgg ccaggttggt gcgggcgaag gcctcgtcgg
    18901 tgcccgagcg ggcggtgacc tcggccaggg cgatgccgtt ggcgggtgcg gccacggtga
    18961 aggtgtgctc ccaggtggag gtcgccgcga cggtggcggt gaccgtggcc tcggccagtt
    19021 cgtggccgtc gaagtccttg acccaccagg acagtgcgac gtcacgtgcg ctcggcgagc
    19081 cgttggcgac ctggacgttg accgtcatcg ccgcgccggg tgtctcccag atgttgaagg
    19141 gccggtcggt ccagatctcg acgccgagtt cccggctggt cccgatcgac gcggtcgccg
    19201 aggggcgtcg ggtggtgaag aagaagtcgg cctcgctgag gtggctcccg tctgcctggg
    19261 tggtgccggg tgcgtggatc caggtggcgt tggtccaggc ctggcgtgag cgttccagca
    19321 ggaacatgcc gtgccgggtg ccccaggtgg aggcgtgggc gacgccgagg gtggtctcgt
    19381 agggcacgcc tccgtcgtcg tcgcggaccc attcggtgat cgcgacgtag gcgtcggcct
    19441 cggtggggtt ctggatcgcg cggctgaaca ggaacccgtc ggggacgagc gtggccgggc
    19501 cggtgacgtg ccaggacagg tggacgtggt cggtggagac ggtgaccagg gcgtggacgg
    19561 cgacggcgcc ggccgccgcg ggcatggtgt agtccacgcg gatcgcgggt gtgccgtcgg
    19621 cgagggtgac caggctcggg gtcccgccgg tggacaggtg gatgccggtg gcggagtcct
    19681 tgatctggaa cttcgatccg gccgagcgga cggttgcctg gccgtcgcgg atggcgatgc
    19741 ggcctccgat gctcgccagg gcgctcaccc cgttcgccga gagcgtgacg tcgccgtcgg
    19801 cggcccaggc gccgaccggg gcggcctcgg cggcgagtac gacacctgcg gcgagggcgg
    19861 ctccgaggag gccgcgccgg gtcattgtgg gcgtgctgcg gtcggacttc atcgtcgtct
    19921 ccgtttcctg cgggcggtcc ggacaggcgc ccgggggatg ggcgggccgg ggtccgcttc
    19981 gtcgccgctc atctgataat tcgcattatc aacggcgtgc ggaacatcgt gcagggcgcg
    20041 agatcttcgc gtcaaggggc ttgcggaagc tgatcatacg gattatcgtc tcgggacacc
    20101 gccgataatg cgcattatcg aaaccgaggg gacaccagac atgacagcca gaccgggcaa
    20161 ggtgacgcaa cgcgagatcg cgcgcatcgc cggggtgagc cagacggtgg tctcgatggt
    20221 gctcaacgac cgcgacgaca ccaacgtccg catccccgcc gccacccgcg agcgggtccg
    20281 ccgggccatc gagcagtcca cctacgtcgc cgaccccgcc gcccgccgcc tcgcgggcct
    20341 ggacaacaag atcctcggcg tcttcaccta cgagtcggcg ctgacgcccg agagcatgga
    20401 cttctacggc cccctcctca acggcatcga acgcgccgcc gaacggctcg gctgcgacct
    20461 gctcttcttc accggctcac cggtcgagga aggccgccgc cgcctcttcc accgcgacac
    20521 ccggctgcgc ctggccgacg gctgcgtcct gctcggccag cagatggacg gcgaggacct
    20581 cgaacgcctc gtcgccgaat ccttcccctt cgtcgccgtc ggccgccgcg acgagaccga
    20641 cgccgacgtc ccctacgtcg gcatcgacta cggcgccctg accgccacac tcatcacacg
    20701 cgccgccgaa ctcggccacc ggcgcgccgt ctacgtccac cgcgaccgcg acagccccac
    20761 cgcccgcgac cgcctcgccg ccatcaccac cagcaccgga caggtcgcct tcaccctcac
    20821 cgccgtcggc gacgacctca ccggactgcc cgggatcatc accgcccaag gggccaccgc
    20881 cgtgttcgcc gaagacgcct tcctcgtcga agacatcgcc ctcgtcctga gcgaagccgg
    20941 aatcaccgcc cccgcacagg tgtccctggc ggcgctgggt gaagtacgcg gccaccgcat
    21001 cgccgaacgc cccctcaccg gcttccaggt cccgcgccag cagatagccg ccgaagccct
    21061 cgccctgctc cagcagctca tctccacccc cgccgacgaa caggccgcca tcaccagaca
    21121 gcgcctcctc caaggcgacg tcgagtacgg cggcaccctc gtcgcccgcg gcggtgcccg
    21181 gtgacacaca tcgagaccga catcgccgtc atcggcggcg gactcggcgg cgtcgccgcc
    21241 gccctggcag ccctcaaacg cggacaccgc gtcgtcctca gcgaggaaca cccgtggctc
    21301 ggcgggcaac tcacctccca ggccgtccca cccgacgagc acatctgggt cgagcagttc
    21361 ggcgtcacca ccacctaccg ctccctgcgc gaaggcatcc gccagtacta ccgcgacgcc
    21421 tacccgctca ccgacaccgc ccgccgcgac ctccagctca accccggccg cggccgcgtc
    21481 agccgcctct gccacgaacc gcgcgtcgcc ctggccgtca tcacccgcat gctcgcaccc
    21541 cacctgtcca gcggccggct caccgtcctc cagccgcacg tgcccatcgc cgccgacacc
    21601 accgacgaca ccgtccactc ggtcaccctg cgccacacca ccaccggcgc cgagacgacc
    21661 gtgtcggcca ccttcgtcct cgacgccacc gagaccggcg agctcctgcc cctcaccggc
    21721 accgcctacg tcaccggcgc cgaaggccgc gacgaga
//
