LOCUS       NZ_JACHGT010000013     25138 bp    DNA     linear   CON 26-SEP-2024
DEFINITION  Phytomonospora endophytica strain YIM 65646 Ga0310468_13, whole
            genome shotgun sequence.
ACCESSION   NZ_JACHGT010000013
VERSION     NZ_JACHGT010000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Phytomonospora endophytica
  ORGANISM  Phytomonospora endophytica
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Phytomonospora.
REFERENCE   1  (bases 1 to 253090)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 253090)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2020) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 173.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014202425.1-RS_2024_09_26
            Annotation Date                   :: 09/26/2024 09:39:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,840
            CDSs (total)                      :: 7,783
            Genes (coding)                    :: 7,704
            CDSs (with protein)               :: 7,704
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 21 of 79
            Pseudo Genes (incomplete)         :: 67 of 79
            Pseudo Genes (internal stop)      :: 5 of 79
            Pseudo Genes (multiple problems)  :: 14 of 79
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:30:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 77160
            Orig. end                         :: 102298
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JACHGT010000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25138
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25138
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25138
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15138](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15138)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            406..1059
                     /locus_tag="HNR73_RS27145"
                     /old_locus_tag="HNR73_005541"
     CDS             406..1059
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020522799.1"
                     /locus_tag="HNR73_RS27145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005541"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_184790478.1"
                     /transl_table=11
                     /translation="MNPLTRHFPLYGLRLTTPRLTLRLPDPAELAALADVAADGVHDAA
                     IMPFNVPWSEAPPAERAFGVVRHHFEMLGRIGAERWAIPFAVFHGDGVVGMQDIGSREF
                     AITRQVGSGSWLGQRFHGKGIGTEMRAAILHLAFDGFGAEVAVSAAHVDNPASLAVSRK
                     LGYRENGTERVTPGGKPNVLQRLLIDREAWAENRAVDVTVEGLDDCRDLLGLPA"
     gene            complement(1119..2729)
                     /locus_tag="HNR73_RS27150"
                     /old_locus_tag="HNR73_005542"
     CDS             complement(1119..2729)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HNR73_RS27150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HNR73_005542"
                     /product="hypothetical protein"
                     /protein_id="WP_184790479.1"
                     /transl_table=11
                     /translation="MSNSFVQQRPLARYARRLAASGAALTLSVAGLSLPASSAQAACVT
                     PSVLAASGAELMRVSTLDVRSLGIDLPPLSDNRLSTSGSAVASLSATKARASADLYQGD
                     VPLDELGLPVVPGKEVTQTAPPHHNKPATGVVSDRDLALVRTGAGELSAHAQWPRHLGC
                     GEGKGPITSTYSAISDAAVLPGGLQLGGSPASSPSLLAIPKTGFTETGADLVRTKAGTD
                     GIAARATAGLEELLLMAGTPASSRIRVIDAPSLKVTTDGSRKNASVAYASPILEIIKPG
                     GKKVRLDSPDKSVEYGLPSRSIMEGGGPLSGNPLSGLLSPLLSGLGLPGLGAQPKLEGI
                     VPPKLPIALDPSLPTPDLAGTGLPDLGLDGLGVPGLGLEGLPVTQGLTAEAADLDEVLT
                     VRISLGHVESRIYPRAVVAEASSARVQIFAKVPGRQSRIPVLDAGIGMLSAAVAVPEMV
                     IFSESADSTGSGEGTNGETAPAVVPEQKRENIAPKSNSLPLTGTGGVLTLIGVGIATIL
                     VGRGIYLLARRKGNAAAGD"
     gene            complement(2859..4457)
                     /locus_tag="HNR73_RS27155"
                     /old_locus_tag="HNR73_005543"
     CDS             complement(2859..4457)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020515340.1"
                     /locus_tag="HNR73_RS27155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005543"
                     /product="metallophosphoesterase"
                     /protein_id="WP_221331168.1"
                     /transl_table=11
                     /translation="MTPPRPQNLHPDQLGFTRRPRVAWLSPLLLLGTAVRVVLAKLLGA
                     YLDKRELQHQFPQETFDHSGGEELWLDYVADLGDGFDSTYTVAYLASQPTLDVDDFTLP
                     RGRVMVMGGDQVYPTASWQDYEDRCKGPYQAALPAGDGGDLYALPGNHDWYDGLTAFLR
                     MFGHRRSIGGRRTGQRRSYFALKLPGDWWLFAIDSNTEAYIDDPQLTYFEEAAKDLRAG
                     HKVIVCLPRPSWVLSCDDPRQFDTVDYLIRTIVTPKGATVPLMLSGDLHHYSRYATDDG
                     GRQLVTWGGGGAYLSGTHDLPEAVAVPHPATTARNASPSESFTKQSSYPSTSASRTWAT
                     GVFWRLPLRNPGFLAVLGALQFGLLLALLGPPTTAVGAGAVLYGVSIVFARPSLGPWKW
                     QNLLAGFLHGTAHLAFALVSLIVWGRLDLAAWWLFADLPVAMVGGGILVTVYLYLAGLL
                     GVNDNELFAGQSIEHAKGFLRIRIGADGGLTIYPLAVPRVNRVWHAVPDGEGERSWIAP
                     TQHVPVTLIEPPISI"
     misc_feature    complement(4371..4373)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4490..4723)
                     /locus_tag="HNR73_RS27160"
                     /old_locus_tag="HNR73_005544"
     CDS             complement(4490..4723)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020006.5"
                     /locus_tag="HNR73_RS27160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005544"
                     /product="DUF1737 domain-containing protein"
                     /protein_id="WP_184790481.1"
                     /transl_table=11
                     /translation="MTSPSGFEARLRYRLITGPDDATFCERISALLDDGYELHGSPSLT
                     FDGERVVAAQAVVLPPYEAVRSRTTHSADPIT"
     tRNA            4917..4989
                     /anticodon=(pos:82110..82112,aa:Thr,seq:cgt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="HNR73_RS27165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="HNR73_005701"
                     /product="tRNA-Thr"
     gene            4917..4989
                     /locus_tag="HNR73_RS27165"
                     /old_locus_tag="HNR73_005701"
     gene            complement(5304..6455)
                     /locus_tag="HNR73_RS27170"
                     /old_locus_tag="HNR73_005545"
     CDS             complement(5304..6455)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HNR73_RS27170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HNR73_005545"
                     /product="hypothetical protein"
                     /protein_id="WP_184790482.1"
                     /transl_table=11
                     /translation="MTHFAIDLQQRTLVASHGTGHGLVGHVVANLPSEVTDKQALHLSH
                     TLTFMSKCLWRCYTHPASAAMDDLAPNSVGWRRQQSREAFSTVLPAITDPNLPNEHGSM
                     IVCYDPVEESAHRVGRALHAIKHTELTERVVSDIECEIAAISSAELGDLTGRAAQAVHL
                     SRADPSPVQIQAAHQLLDNDPLGGSELFTDLDPTAAAVAAAHWLHAAAEVAGELAGVDT
                     TRVLFEADNITAIQLETPTYVLEQIKTGRTPLDIVTELIRNALKVADGEIPDLDALKAD
                     VALAEQRAGEYRVSSPETAAALLKELRVTLLDPMRPARDLLEDLLDGIRGCWTLFREVS
                     FEIELEDEDDEPLDLDDEDEEPEDDEATLAEFCELLRLEVDRD"
     gene            6653..7195
                     /locus_tag="HNR73_RS27175"
                     /old_locus_tag="HNR73_005546"
     CDS             6653..7195
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HNR73_RS27175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HNR73_005546"
                     /product="hypothetical protein"
                     /protein_id="WP_184790483.1"
                     /transl_table=11
                     /translation="MALERRAHQAGIFSAVVAVLALLWGIFVYVVPGQQSGSGSDATSS
                     GDEAPGADSGEQSPRSVEAWQGTMLFDDGGVDFDTDPPTKASSPDPRIDAYNGDGSIVT
                     YGWTLKNVARWSGEDAPNAEDCAGLLQTHAVYEADYDKGSRFCVRSRGLERIVFVEFLE
                     PIDTAWEIQVTVWNTRA"
     gene            complement(7538..8779)
                     /gene="fxlM"
                     /locus_tag="HNR73_RS27180"
                     /old_locus_tag="HNR73_005547"
     CDS             complement(7538..8779)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04364.1"
                     /locus_tag="HNR73_RS27180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005547"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_184790484.1"
                     /sec_met_domain="PCMT (E-value: 1.8e-48, bitscore: 158.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTIDQTNTGEKDQDAAVLRSHLVDKLRDEQFLRTERVEQAMQTV
                     QRHLFLPEETTARAYEDDHVVTKWAADGKALSSASAPWIVAAMLEDLDVQPGQRVLEIG
                     AGTGYNAALVRELVGPTGSVTSIDIDADVVETARQNLTSAGYDDIHLVTGDGAEGHSAH
                     APFDRIVATAGCWDIPAAWWEQLTKSGRLVIPLRWRGDSRIVAFGRDGDRLISERIFMG
                     GFIPMRDHGSERTFTVGPNDAITVTCDSDQDINRDALTGVFEQERSESWSGVTVKDGEP
                     WDVLWLRMASYEAGACRLTTTRDAIAAGHVPEDLPPWTHALVEGTSLAYFTTRSAPEER
                     RCELGTSGYGPAGQELADRISDHIRAWGPDRAATPTITAWRTKPDTSTAYPIISKVNTC
                     LIAEESSPQLPSHR"
     misc_feature    complement(8770..8785)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.74"
                     /tool="antismash"
     gene            complement(8874..9890)
                     /locus_tag="HNR73_RS27185"
                     /old_locus_tag="HNR73_005548"
     CDS             complement(8874..9890)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HNR73_RS27185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HNR73_005548"
                     /product="hypothetical protein"
                     /protein_id="WP_221331169.1"
                     /transl_table=11
                     /translation="MREHDLSAAASACNLAALAASDAGKPDLARHWCHDQYTRYTRHQA
                     LPGPAAIHALEPVINLARLRLRAGDGDTAHRFLLNMHDAAVSRSSTNVDGLTVDFAALT
                     DEEGHQAVVEKLWAVLLADGTRALTSQGHWDQALDQLTVHRGIGRRLLDGRQTAIIAHQ
                     LAGRRNTARELLADTTCTEPWEYLLLDSLQARLQTPAALVSEKDPAGLVSLWLAYQPET
                     GLQLFTTQLGLMIYELLTSLGTASAIQRLRDQIIEDGLSGRDAYVAREILGDPAVSGTL
                     SPHEHAEFETTCRRANLGSGTLPEEHQRTLASAVQDALAATTSTLSTTNRNQSTSVG"
     gene            complement(10001..10828)
                     /locus_tag="HNR73_RS27190"
                     /old_locus_tag="HNR73_005549"
     CDS             complement(10001..10828)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="HNR73_RS27190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005549"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_184790486.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.5e-36, bitscore:
                     119.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNTDSWRQINVAFTDPATAETTAVIHLAPILAAADTNGAVSPWF
                     FIRKTPSWRIRCQPADPNIWCDIRGQFRALVHAGHIADMTEVVYEPESHAFGGPDGMAV
                     AHALFHTDSQQILHHLASAVHAERDRRRELALLLPTFMLRAAGQDWYEQGDVWARVAEH
                     RTPPASVPLQLPSTVHRLISVDASSLTRTGQPLAHIHAWAKAYTDAGRQLAMLNETGQL
                     QRGLRRILAHHIVFAWNRLGLSASAQSILASTAATVIFGEPRLSLPLANGATA"
     misc_feature    complement(10797..10810)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     gene            complement(10856..12094)
                     /locus_tag="HNR73_RS27195"
                     /old_locus_tag="HNR73_005550"
     CDS             complement(10856..12094)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018831026.1"
                     /locus_tag="HNR73_RS27195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005550"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_184790487.1"
                     /sec_met_domain="LANC_like (E-value: 1.4e-42, bitscore:
                     139.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTISTFDTDALAVASTISEALAKPGMDPTQPPRDQRTLSQSLAGG
                     AAGMALLHITRAHTGHGDPATADTWLRLAAAGPVSAADNANLFFGAPTLAYLLHIASER
                     TPAYQGALAKLDDAVVAITTRRLTDAHRRIDNGEALLMREFDLIHGLVGLGVHLLRRHP
                     DHDVTRDVLAYLVRLTEPKGGTAGLPSWWMPTGPSGQSDQDFPDGHGNFGLSHGIAGVL
                     ALLSLSVIRGAAVPGVVDAIGRICAWTDQWLQCSDGAAWWPGLITLDQHHIRRIDPILR
                     PRPSWCYGIAGAARAQQLAGLALRDARRQELAEEAILAVFKDPDQLDRLDGPGLCHGTA
                     GLLQSAWRIAADALTPSNIHAELPQLTRHLIEQLARSDTEPELMDGTAGAALTLHSVAT
                     GVVPDWDAFLLLS"
     gene            complement(12091..15138)
                     /locus_tag="HNR73_RS27200"
                     /old_locus_tag="HNR73_005551"
     CDS             complement(12091..15138)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="HNR73_RS27200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005551"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_203686390.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.5e-174,
                     bitscore: 575.6, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2e-17,
                     bitscore: 57.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5e-30, bitscore:
                     99.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVRAATLPTSTSRGHWPNLGPTATVKDWRDWLEKVLDLPGFAEAL
                     YEASPVLAGRVDAIRNAAEVSPKNAQGAVLSVLRYLLRASGRATPFGLFAGVAPARVAQ
                     AGHALIGTRHQPRARLQAAWLSAVIDRLESIPAVRSQLLVTANNLIVERDGRLLLTRSG
                     TTAKDSPIQVSVRATSPARTAIAMAAEPISVAELEGKLAAAYDEAPSASVAALLNALVS
                     QRLLITSLRPSMTSTDPLAHLAQALEACGATDIPEAAVVLESLNEIRQIVVTQDRASTP
                     AGRHTERTRLDACTSAVASIAGSAVAIDLKLDAKVTVPESVAVEAAAAATVLTRLARPP
                     APEWVAWHGRFLERFGLGALVPVTQAVDEGTGLGFPVGFGDGPPGRRAAITSRDERLLA
                     LAQHAALRRQREVVLDEALIAELAGDTRPGLAGVQPSTEITARVHARGTEELNRGAFTL
                     AITGVSRNAGTTTGRFLDLLDSADRDAFTTAYGSMPMRTRGALPVQVCTALPYTATENV
                     ARAPQVLPHLLVLGELRPSHHAHLALDDIAVTADAHRLWLVWLSHGRVVEPLLFNAVEP
                     SRYLFPLVRFLTEAPGALGTACHGFEWGQAAARLPFLPAVRFGRTLLAPARWRVSKHEL
                     PGRPVNPQTFKEAVEHWRETVACPARVYLGDGDRRIGIDLTEPACHELVRSDLESLGQA
                     TLRAAPPDDADGWTSGHVHEIVIPLAATSSGVDGPPQPPGRDRVVQVREHGRPPGGRDG
                     LYVKVYSAANLHDAILTDHLPRLLSVLDPATRWWFLRYADPEPHLRLRLEALADRSGET
                     TASVHAWMQRLRTAGLASRMVFDTDFPETNRFGGENALTAAEIYFAADSAAALTQLTLD
                     RDTAIDIRAVTAASLLDLAIAANGGDSVAGMHWLVDHTRSHRTAPPRDLYDQAVALAAP
                     DRHELATLPGGKPVLSSWRLRHQGLDSYRAALSDYSTISLSSLLPDLLHLHFTRIHGAD
                     SDAERACLHLARAAALSWTRRARSTP"
     aSDomain        complement(14440..14709)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HNR73_RS27200_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.30E-18"
                     /identifier="RREFam001.1"
                     /label="HNR73_RS27200"
                     /locus_tag="HNR73_RS27200"
                     /protein_end="233"
                     /protein_start="143"
                     /score="57.7"
                     /tool="antismash"
                     /translation="VTANNLIVERDGRLLLTRSGTTAKDSPIQVSVRATSPARTAIAMA
                     AEPISVAELEGKLAAAYDEAPSASVAALLNALVSQRLLITSLRPS"
     misc_feature    complement(14812..14814)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15266..15436)
                     /locus_tag="HNR73_RS27205"
                     /old_locus_tag="HNR73_005552"
     CDS             complement(15266..15436)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018724312.1"
                     /locus_tag="HNR73_RS27205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005552"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_184790489.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 2.4e-17, bitscore:
                     56.6, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTSTIETVDVSVKDLGNWDLDITIVESGPNADRLIHMTNDGCGQ
                     TCQSACSTTCP"
     gene            complement(15511..16722)
                     /gene="fxlM"
                     /locus_tag="HNR73_RS27210"
                     /old_locus_tag="HNR73_005553"
     CDS             complement(15511..16722)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Methyltransf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04364.1"
                     /locus_tag="HNR73_RS27210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005553"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_184790490.1"
                     /sec_met_domain="PCMT (E-value: 1.6e-38, bitscore: 126.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="Methyltransf_3 (E-value: 5.5e-07,
                     bitscore: 23.0, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLPEQQVHDPGVLRADMIRELQAMEALWSPPVIDAVAAVPRHL
                     FAPGEPLEAVYEPNTPLVTKWAPDGKAVSSLSATAIQTVMLEQAEITPGMKVLEIGSGG
                     YNAALLAELVGPDGHVTTVDIDPDITDRARSCLNAAGYERVDVVTADAEHGVASNAPYD
                     RIIVTVGAWDIPPAWLDQLTADGRIVVPLRFAGLTRSIAFDRTSEGLASVNYYLSGFVA
                     IQGAGEFNETLVSVTDDAVLRLDERAPKLDIAGLRAAFDSPRREYWSSAAFDLPDELEL
                     FLVTSAPVVPLLHVSAGLVESGAFAASAGRGVPVMIDGDSFAYRTKRANDAVGGFESGV
                     IAHGSNADQVAERYLQLLRDWATNHRRRGAAQIGYLPATSLTDIPAGTWQAQKNHGRIT
                     VSWG"
     misc_feature    complement(16737..16751)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            17283..18572
                     /locus_tag="HNR73_RS27215"
                     /old_locus_tag="HNR73_005554"
     CDS             17283..18572
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.5"
                     /locus_tag="HNR73_RS27215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005554"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_184790491.1"
                     /transl_table=11
                     /translation="MGQAPKELTPTASPLHFFGAQLRELRETAGLSQAELGRVTLNSAD
                     LVRKIETAERAASRQFVDRCDEVLCGGGMLRRLWPLLERERELRSTIADQRDHGTLGPS
                     ARAEDRLVLDWLLAHNAGDVGPEPPQLDLATHAAERLMRFREVDHLQGAGRTYPEVADV
                     VRRDLQKLSQTAPSVAIGYLELAGYEAVDLGADTQARGHYLRALEITTRTGNRLYGGYL
                     IGVSLAHLALHGGDARHAIRLVNAGLRGVADCATPAVRAAIQVVAARAHARLGDERASA
                     AALHQVDVDLDRSRPAEEPEWIGYFGPADLADEKAHCFFDLGLHDRAQDEAATAIGLLH
                     PSRMRRLAIDSSLHATSLARSGDLDRACAVAHEAIDYTAGTTSFRSAHRVTMMLAELHP
                     HATIPSVREVNDYARTVLADAPVSLADLPG"
     misc_feature    17326..17342
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.25"
                     /tool="antismash"
     misc_feature    17583..17585
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18547..20232)
                     /locus_tag="HNR73_RS27220"
                     /old_locus_tag="HNR73_005555"
     CDS             complement(18547..20232)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018799931.1"
                     /locus_tag="HNR73_RS27220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005555"
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="WP_239122184.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 5.8e-29, bitscore:
                     95.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFWVESRPEQGVDVVATWTPQEVPTFTTIPVGNSIHAYGGGTYAV
                     SPRGIWVVSSDDGRIWLDGGSAYTSPGSAGDLRFAGGLLLFVRETDTYDELVVIDPDSG
                     GEVVLRTAGFIASPSLSDGRLAWVEWPVDVMPWDQAEVWVADLVQGQELKNPTLVAGGP
                     TEAATQPQWGPDGTLYFMSDRGSGWQNLHRWDGAGIELLVPMEADCAEALWELGYSSYG
                     FLPDGRIAMVAQNGVEHRLVLAEASGAVTPLATPYTFFKPYLAVYGDHVAVIGSSPTVP
                     QQVALVATDGSGAIEVIRSGPEPATDAAVSAPQILRVDSDGVPITVVYYPPLSCVPGQA
                     APLIVRAHPGPTHHNELRLDAEIQFFTSRGFAVADVDYGGSTGYGRAFRKTLDHRWGEL
                     DVADCCNAAVGLIDLGLAEPGTIFITGASAGGYTALRAVSSPDTPFALAAARSAIVDPN
                     RWVETAPRFQRPHAAILTHATAGVEADRVSRPVLLVHGDADMVAPAADVRELAEALKSR
                     GMLAGYLPLADVGHYLSKPEALNAALSAELAAYEAVINRADPRG"
     gene            20653..22743
                     /locus_tag="HNR73_RS27225"
                     /old_locus_tag="HNR73_005556"
     CDS             20653..22743
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HNR73_RS27225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HNR73_005556"
                     /product="hypothetical protein"
                     /protein_id="WP_184790492.1"
                     /transl_table=11
                     /translation="MTVEEGVAVDDPGLADCADCQGLGAAFMSCQCRRDDQRTSDFIRR
                     VGNLFGIGRSDGPCLQCNGDGAISHRCYRCQGFGRVRAQLVYVLINLDLGTIASTVIEP
                     GAFTPVRIPTGGWCIDSEVIVDELAARLGVAHVEAADGLSKLQAILLPKEWRPDLDDYE
                     RLKLEATTIARASGLGRWKILFGRMEEPAPLDADSTLTQLCRLASALCLDLVIDKRRFR
                     HPRGNPGGFHWDVRFETSGTPVAAPRKIGGSSSLAEALAKADPLKLLENLPRYDRTAPA
                     YRLAPAEPPADLDLRIAAIEDELNTTGDSPVGAIATWCDSRWHYSSLRSVAEIDGTEFI
                     ERIQSPPRPAYWAEPVFSRECHACADGPEYRYCHCAIDGNKADAGCVSCAGTGIKESRT
                     GCFTCGKVGEIRAGAVVTITDLDQHHTFIDLSPDADAEITDAGLTPGNATIWQLPDRYR
                     LSHWLSTLGIPTDQVIDPTGAAMGVDNHLERGSVYDFHGTITTALDATSAYLADITKGR
                     TGARIIIVDSTPAWRPLESLAAIATGLQMTLEVVVRCYHHCEGDIGAIHGDLWGVHLRA
                     IDAAPDKLNHGHHISLRAAVNASFTSLGQQLSRTARDTNPTVGLPAPQQPHPPVTDLTG
                     LEQVMHTLAERYTPPTGTTIACRLSPGRVSIHHQPSHSSRGPMTILAEGRDLSEIVPLL
                     GL"
     gene            22774..23028
                     /locus_tag="HNR73_RS27230"
                     /old_locus_tag="HNR73_005557"
     CDS             22774..23028
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HNR73_RS27230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HNR73_005557"
                     /product="hypothetical protein"
                     /protein_id="WP_184790493.1"
                     /transl_table=11
                     /translation="MASIDDLLGSLETLKGAIDQSKSAANGARSVADETYSQFQGLGAE
                     GVAAILNTAKDQIEASFSALDQAMNEAEQARATAESAKG"
     gene            23227..23637
                     /locus_tag="HNR73_RS27235"
                     /old_locus_tag="HNR73_005558"
     CDS             23227..23637
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025786.5"
                     /locus_tag="HNR73_RS27235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNR73_005558"
                     /product="Imm1 family immunity protein"
                     /protein_id="WP_184790494.1"
                     /transl_table=11
                     /translation="MPHTAWWSYDSRTLDSPTDVEDLFATATTTWYSNAVKAIRILIGP
                     AGTDETRAPLQVDIDIDEGRAHVRWRPDDTLGFEEGAKPHHRSLRVHIQSDEPLATLEG
                     ADCLVTPGYALRAVEEYTETGARPGCLGWRPY"
     misc_feature    24674..24689
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.97"
                     /tool="antismash"
ORIGIN
        1 ctcgaaccac acgggttcac cgtcgaatac gtccgactcc acgagcggat cctccacctc
       61 gactgcgccc tcggcctcat ccgcgacggg cttctcgtgc acagccccga cgcgctcccc
      121 gacgggctcc cggaaagcct gcgcgactgg gaatccgtgc cgatcacctt cgaccaggcc
      181 acctccctcg ccaccaacgg cctccccatc acacccgacg tctacgtcac cgaccccgcg
      241 ttctccttcg tcggcgaccg gctcgcgaag gcgggcgtgc gcgtcgagta cgtcgacttc
      301 tccatcaccc gctcgctcgg cggatccttc cggtgcagca cccaggcact gctgcgggcc
      361 taaaacccct cgccaagcac cgccgccacc ccgcaccatc cctgcatgaa cccgctgacc
      421 cgccacttcc cgctctacgg cctccgcctc accaccccgc gactcaccct ccggctgccc
      481 gatccggccg aactcgcggc actcgccgat gtcgcggccg acggggtgca cgacgcggcg
      541 atcatgccct tcaacgtccc gtggtcggag gcgccgcccg cggaacgggc cttcggtgtc
      601 gtccggcatc acttcgagat gctcgggcgg atcggcgccg aacggtgggc gatccccttc
      661 gcggtgttcc acggcgacgg ggtcgtcgga atgcaggaca tcggctcgcg ggagttcgcg
      721 atcacccggc aggtcgggtc gggatcgtgg ctggggcagc gcttccacgg caagggcatc
      781 ggcacggaga tgcgcgcggc gatcctgcac ctggcgttcg acggcttcgg cgcggaggtc
      841 gcggtgtcgg ccgcgcacgt cgacaatccg gcgtcgctgg cggtgtcgcg caagctcggt
      901 taccgcgaga acgggaccga gcgggtgacg ccgggcggga agcccaatgt gttgcagcgc
      961 ctgctgatcg accgcgaggc ctgggcggag aaccgcgccg tcgacgtgac cgtcgaaggt
     1021 ctcgacgact gccgcgacct gctcggtctg cccgcatagc gcggggcccg ccggtggggt
     1081 tgcaccgacg ggccccttgg gggagtgcca ggtgaggtct agtcgccggc ggcggcgttg
     1141 cccttgcgtc gggcgaggag gtagatcccg cgccccacca ggatcgtggc tatcccgaca
     1201 ccgatcagtg tcagcacacc accggtgccc gtcagcggca gcgagttcga cttcggcgcg
     1261 atgttctccc gcttctgttc cggcacgacg gccggggccg tctcgccgtt cgtgccctcg
     1321 ccggagccgg tggagtccgc gctctcactg aagatcacca tctccgggac ggcgacggcg
     1381 gcactgagca tcccgattcc ggcgtccagc acgggaatcc gcgactggcg gccaggcacc
     1441 ttcgcgaaga tctgcacacg cgccgaggag gcctcggcga cgaccgcgcg cgggtagatc
     1501 cggctctcga catggccgag actgatccgg accgtgagaa cctcgtcgag gtcggccgcc
     1561 tcggccgtca ggccctgcgt cacgggcagc ccttcgagac cgagaccggg cacgccgaga
     1621 ccgtcgaggc cgaggtcggg caggcccgtg cccgccaggt cgggcgtcgg gaggctcggg
     1681 tcgagcgcga tcggcagctt cggcgggacg atgccctcca gcttcggctg cgcgccgaga
     1741 ccgggcaggc ccagccccga cagcagcggg gaaagcaggc cggacagggg attgcccgac
     1801 agcgggccgc caccctccat gatggaccgc gacggaaggc cgtactcgac gctcttgtcg
     1861 ggagagtcga gccgcacctt cttgccgccc ggcttgatga tctccaggat cggcgaagcg
     1921 taggccaccg aggcgttctt cctgctcccg tcggtggtga ccttcaggga aggcgcgtcg
     1981 atgacccgga tccggctgct cgcgggcgtt cccgccatca gcagcaactc ttcgagcccg
     2041 gccgtggcac gcgcggcgat gccgtcggtg ccggccttcg tgcggaccag gtccgcgccg
     2101 gtctcggtga acccggtctt cgggatcgcc aggagactcg gcgacgaggc cggcgaaccg
     2161 ccgagctgaa gaccgcccgg aagtacggcg gcgtcactga tcgcgctgta ggtgctggtg
     2221 atcggccctt tgccctcacc gcagccgagg tggcggggcc actgggcgtg cgcgctgagc
     2281 tcgcccgcgc cggtccgcac cagcgcgagg tcgcggtcgg agacgacacc ggtcgcgggc
     2341 ttgttgtggt ggggcggagc ggtctgcgtg acctctttcc ccggcacgac gggcaatccg
     2401 agctcgtcca ggggcacgtc gccctggtac aggtcggccg aggcgcgggc cttcgtcgcg
     2461 ctcaagctcg ccacggcact gccgctggtg gagagccggt tgtcgctcaa cgggggcagg
     2521 tcgatgccga gcgaacgaac gtccaaggta gacactcgca tgagttcggc accactggcc
     2581 gccagcacgc tcggggtcac gcacgccgcc tgcgccgacg acgcgggcag cgagaggccc
     2641 gccaccgaga gcgtgagcgc cgcgccgctc gcggcgagac gccgcgcgta gcgcgccagg
     2701 ggtcgctgct ggacaaatga attgctcatc cggtccttcc gttacgccgg ttggggagtg
     2761 gacgagggcc ctcaccagac gcaacgagac agtgatggga gggttacgcg acgcaagcga
     2821 aaccctcgct caattgtccg aaaggcggcg ttaaatgcct aaatggatat aggaggttcg
     2881 atgagtgtca ccggaacgtg ttgcgtgggg gcgatccagg accgctcgcc ctcaccgtcg
     2941 ggaacggcgt gccacacccg gttgacgcgc gggacggcca aggggtagat cgtcaacccg
     3001 ccgtccgcgc cgatccggat gcgcaggaag cccttcgcgt gctcgatcga ctgccccgcg
     3061 aacaactcgt tgtcgttgac cccgagcagc ccggcgaggt acaggtagac cgtcaccagg
     3121 atcccgccgc cgaccatcgc gaccggcagg tcggcgaaca gccaccacgc ggccagatcc
     3181 agccggcccc agacgatgag gctgaccaac gcgaaggcca gatgcgctgt gccgtgcagg
     3241 aacccggcga ggaggttctg ccacttccac ggccccagcg aaggtcgcgc gaagacgatc
     3301 gagacgccgt agaggaccgc gccggcaccg accgccgtcg tcggcgggcc cagcagggcc
     3361 agcagcaggc cgaactgcag ggcgccgagc acggcgagga aacccgggtt gcggagggga
     3421 agccgccaga acacacccgt cgcccacgtc cgcgaagcgg acgtggacgg gtaggaggac
     3481 tgcttcgtga acgactccga cgggctcgcg ttgcgtgccg tcgtcgccgg atgcggcacc
     3541 gcgacggcct ccgggaggtc gtgcgtgccc gacaggtacg cgccgccgcc gccccacgtc
     3601 accagctggc ggccgccatc gtcggtggcg taacgggagt agtggtgcag gtcgccggac
     3661 aacatcagcg gcaccgtcgc gcccttgggc gtgacgatgg tgcggatgag gtagtcgacg
     3721 gtgtcgaact ggcgcggatc gtcgcaactg agcacccacg acggccgcgg caggcagacg
     3781 atcaccttgt gaccggcccg cagatccttc gcggcctcct cgaagtaggt cagctgcgga
     3841 tcgtcgatgt aggcctcggt gttggagtcg atggcgaaga gccaccagtc acccgggagt
     3901 ttcaacgcga agtagctgcg ccgctggccc gtccggcggc cgccgatcga acgacggtga
     3961 ccgaacatgc gcaggaacgc cgtcaggccg tcgtaccagt cgtggttgcc gggcagggcg
     4021 tagagatcgc cgccgtcgcc cgcgggaagg gccgcctgat acgggccctt gcaacggtcc
     4081 tcgtagtcct gccacgacgc cgtcgggtag acctgatcgc cgcccatgac catgacgcgg
     4141 ccgcgtggga gcgtgaagtc gtcgacgtcg agcgtcggct gactcgccag atacgccacg
     4201 gtgtacgtcg agtcgaaacc gtcgcccagg tcggcgacgt agtcgagcca cagctcctcg
     4261 ccgccggagt ggtcgaaggt ctcctgcggg aactggtgct gcagctcacg cttgtcgaga
     4321 taggcgccca agagcttcgc cagcaccacc cgcaccgccg tgccgagaag taagagcggc
     4381 gacaaccacg ccacacgggg ccgacgcgtg aagccgagct ggtcggggtg caggttctgc
     4441 ggacgaggag gggtcacctg tccattgtgt cccggtgggg tggcgaccgt cacgtgatgg
     4501 ggtcggcgga atgagtcgtg cgcgaacgga ctgcctcata gggcggcagg acgaccgcct
     4561 gcgcggcgac gacgcgctcg ccgtcgaagg tgaggctcgg ggagccgtgg agttcgtagc
     4621 cgtcgtcgag cagcgccgag atgcgctcgc agaacgtcgc gtcgtccggg ccggtgatca
     4681 gccggtagcg cagtcgggct tcgaacccgc tcggggaagt catcggggca cgccctcacg
     4741 tcgactcgcc ggaggcggtg gcccccgcgc caagacccta tcgcgcgggg gcggggcggg
     4801 ggcggggtcg gtggctgccg ggcgggtcgg tcgggggtag ttcggcaacc catttcgcgc
     4861 gggccggggg gatcacgtac actcgaccgc tgtacccgtg tgtttcgtgg gtgcgcgccg
     4921 ccttagctca gtcggcagag cgattcactc gtaatgaata ggtcgtcggt tcgattccga
     4981 caggcggctc agtgttcgag caggtcagag gcccgcttcc ctggttgggg agcgggcctc
     5041 ttgatcattt gaccgtgatt tgaccgtgag atttttcgtc acgagccgat atcagcgagg
     5101 ctgagacgcg cgtcacgcgc tcagtccagg ccgtcgagcg gggctcgatt gttcaactag
     5161 cgacacctgt ccgcgcccgc taaagaccca tatcggccct caccgtaggt ccggcgggct
     5221 cgcgccgggt actcgtgcat ccggtttaca aggcgcttgc ggagcctggc agggcggggc
     5281 ggttgagagc ggcgacgccc gtgtcagtct cgatcgacct ctaggcgcag cagctcgcag
     5341 aactcggcga gcgtggcttc gtcgtcctct ggttcctcgt cctcatcgtc aaggtccaac
     5401 ggctcgtcgt cttcatcctc gagttcgatc tcgaacgaaa cctcccggaa gagcgtccag
     5461 cagccgcgga tcccgtcgag gagatcctcc agaaggtcac gggccggccg catcgggtcc
     5521 agcagcgtga cgcgaagttc tttgaggaga gcagcggccg tctcggggct gctgacgcgg
     5581 tactcgccgg ctcgctgctc agcgagggca acatcagcct tgagcgcgtc gagatcaggg
     5641 atctcgccgt cggcgacctt gagggcgttt cggatcagct cggtgacgat gtccagcggc
     5701 gtccggccgg tcttgatctg ctccaaaacg tatgttggtg tttcgagttg gatggcggtg
     5761 atgttgtccg cttcgaacaa cacgcgcgta gtgtcaacgc ccgcgagttc tccggccact
     5821 tcggcggcgg catgcaacca gtgagccgcg gcgacagctg cggcggtcgg gtcgagatcg
     5881 gtgaagagct cgctgcctcc gagagggtcg ttgtccagca gctggtgagc agcctggatc
     5941 tgaaccggtg acggatcagc ccgtgagagg tgcaccgctt gtgcggcgcg ccctgtcaga
     6001 tcgccgagtt cggcagatga gatcgcggcg atttcgcatt caatgtcact gacgacgcgt
     6061 tcggtcagtt cagtgtgctt gatggcgtgt agggcgcggc ccaccctgtg cgcggactcc
     6121 tcaacggggt cgtagcaaac gatcatgctg ccgtgctcat ttggaaggtt cgggtctgtg
     6181 atcgcgggaa ggacggtcga gaaggcttcc cgggactgct gccgtcgcca accgactgag
     6241 tttggtgcga ggtcgtccat cgcggcgctc gccgggtgcg tgtagcaccg ccagaggcac
     6301 ttcgacatga aggtcagcgt gtgggagagg tggagagctt gcttgtcggt gacctccgag
     6361 ggcagattgg cgaccacatg acccacaagc ccgtggccgg tgccgtggct cgccacgagt
     6421 gtgcgctgct gaagatcgat ggcgaaatga gtcaaccgaa cccccgtagg tctattttgg
     6481 acgaccaaga gtgacatgtt cgtggctggg cgccaacccc tccagtcatg atcgttgacc
     6541 cggtcggacg tatccggtgt gctgcgtctc gacgcgcagg gaaggtccta tgtagtcgat
     6601 agcctggatg tgtcgtggtg tcgtctggta ggggccgtga agggacgtga cgatggcctt
     6661 ggagcgacgt gctcatcagg cagggatctt cagcgccgtc gtggcggtgc tcgcgctgct
     6721 ctggggcata ttcgtctatg tggtgcccgg ccaacagagc ggatcgggga gtgatgcaac
     6781 ttcgtctggc gatgaggctc ctggtgccga ctcgggcgag cagagcccaa ggtcagtgga
     6841 agcctggcag ggcacgatgc tcttcgatga cggcggtgtc gacttcgata cggatccccc
     6901 cacaaaggcg tcgagcccag acccgaggat tgacgcttac aacggcgacg ggtcgatcgt
     6961 gacctacggc tggaccttga agaacgtggc tcggtggagc ggtgaggacg cgccgaacgc
     7021 cgaggactgc gccggacttc tgcagacgca tgccgtgtac gaagctgact atgacaaagg
     7081 cagccgcttt tgcgttcgct cacgtgggct ggagcggatc gtgtttgttg agtttctcga
     7141 gcccatagat accgcctggg agatccaggt gaccgtctgg aacacgcggg cctgaactcg
     7201 cgttcattga gaacggcagt catctggcgg cgctctgtca aggcggaggt tgcgggtttc
     7261 aagtcccgtc gggaccgcaa cgtaggtgca ggtcaggccc catttccgga aacggagagg
     7321 gggccttttt cgtctcattg tcgcttcgtt gtcgcggatg tgctggcacc tgtcggagcg
     7381 cggcagcatc aaagtgaccc atggcacgtc tcgctgccgt tccgaggacg tgagaagcgc
     7441 atccgttcca agggcgctcc agcgacatgg caactgtcat gacagttgcc atgtcgctgg
     7501 agggttcaac ctgaaccacg cagaatcggc accaccttca gcggtgtgac ggcagctgcg
     7561 gcgatgactc ttcggcgatc aggcaggtgt tgaccttgga gatgatcggg tatgccgtgg
     7621 atgtgtcggg cttggtgcgc caggcggtga tggtcggggt ggcggctcgg tcgggacccc
     7681 aagcgcggat gtgatcgctg atccgatcgg cgagttcctg gcctgcaggg ccgtagccag
     7741 aggtgccgag ttcgcagcgg cgttcttctg gggcggagcg ggtggtgaag tacgccagcg
     7801 aggtgccctc gacgagagcg tgggtccagg gtggcaggtc ctccggtacg tgtcctgctg
     7861 cgatggcgtc gcgcgtggtg gtcaggcggc aggcaccggc ttcgtagctg gccatgcgca
     7921 gccacaggac gtcccagggc tccccgtctt taacggttac ccctgaccac gactcgctgc
     7981 gctcctgctc gaacacaccg gtcagggcgt cgcggttgat gtcctgatcg gagtcgcagg
     8041 tgaccgtgat ggcatcgttc gggccgacgg tgaaggtgcg ttcgctgcca tggtcgcgca
     8101 tggggatgaa cccgcccatg aagatccgct cgctgatcaa gcggtccccg tcgcgaccga
     8161 aggccacgat gcgggagtcg cctctccacc gcagagggat caccaggcgt ccggacttgg
     8221 tgagctgctc ccaccacgcg gcgggtatat cccagcaccc ggccgtggcg acgatccgat
     8281 cgaacggggc gtgggcggaa tgcccttctg ccccgtcacc ggtgacgaga tggatgtcgt
     8341 cgtagccggc gctggtcagg ttctgtcgcg ctgtttcgac gacatcggcg tcgatgtcga
     8401 tgctggtgac actgccggta gggccgacga gttctcgcac gagcgcggcg ttgtagccgg
     8461 tgccggcccc gatctccaga acgcgctgcc cgggctggac atcgaggtct tcgagcatcg
     8521 ctgcgacgat ccagggtgcg gatgccgagc tgagggcctt gccgtcagcg gcccacttgg
     8581 tgaccacgtg gtcgtcttcg tacgcgcggg cggttgtttc ttcgggcagg aacaggtgcc
     8641 gctggactgt ctgcatcgcc tgctcgacgc gctcggtacg caggaactgc tcatcgcgga
     8701 gcttgtcgac caggtgcgag cgtagaacag cggcatcttg gtccttttca ccggtgttgg
     8761 tctgatcgat ggtcgtcatc ggcgtgtcct catcggatgt tgggcatggt ggtcgtgagg
     8821 gctggtgttc aggggatggt gcggactggc ctggggacgg tccgatacgg cagtcaccct
     8881 accgaagtgc tctggttacg gttcgtggtc gagagggtgg aggtggtggc ggcgagcgcg
     8941 tcctgcacag ctgatgcgag ggtgcgttgg tgctcttcgg ggagggttcc gctgcccagg
     9001 ttggctcgtc ggcaggtggt ttcgaactcg gcgtgttcgt gtggcgagag tgtgccgctg
     9061 acggcggggt cgccgaggat ctcgcgggcc acgtaggcat cgcgcccgga caggccgtct
     9121 tcgatgatct ggtctcgaag ccgttggatg gctgatgccg tcccgagcga tgtgagcagc
     9181 tcgtagatca tcagcccgag ctgtgtggtg aagagttgta ggccggtttc gggttggtag
     9241 gcgagccaga gtgagacgag tccggctggg tccttctcac tgacgagagc tgctggcgtc
     9301 tgtaggcgtg cttggaggct gtcgaggagc aggtactccc atggttcggt gcaggtggtg
     9361 tcggcaagga gttcccgggc agtgttgcgg cgaccggcga gttgatgggc gatgatcgcg
     9421 gtttggcgtc cgtccagtag ccgtctgccg atgccgcggt ggacggtgag ttgatcgagg
     9481 gcttggtccc agtggccttg gctcgtgagg gcgcgagtgc cgtcggcgag caggacagcc
     9541 cagagcttct cgacgaccgc ctggtgccct tcctcatcgg tcagtgcggc gaagtcgacg
     9601 gtcaggccgt caacattggt ggaggagcgg ctgactgcgg cgtcgtgcat gttgagaagg
     9661 aaccggtgcg cagtgtcgcc gtcgccggcg cggagtcgga ggcgggcaag gttgatgacc
     9721 ggttcgaggg cgtggatcgc ggccggacca ggaagtgcct ggtgccgggt atagcgggtg
     9781 tactggtcat ggcaccagtg gcgagccaag tcgggtttgc ccgcgtcgct ggcggcgagg
     9841 gcggcgaggt tgcaggcgga tgcggcggca ctcaagtcgt gttcccgcat ggccttggtg
     9901 gcgagttcgg tgatagccgc gacgcgttgg gcaatgggtg gacaggcggg tcgtggccgc
     9961 ggaacgagtg ggaatcggcg ggcaaggccg tgtcgggggg tcatgcggtg gcgccgttgg
    10021 cgagaggcag cgaaagccgt ggctcgccga agatgacggt ggccgccgtc gaggccagga
    10081 tcgattgtgc ggaggcagaa agtccgagcc ggttccaggc gaagacgatg tggtgggcaa
    10141 gtatgcgtcg aaggccacgc tggagttgtc cggtttcgtt gagcatggcc agctgtcggc
    10201 ccgcgtcggt gtatgccttc gcccatgcgt ggatgtgtgc gagaggctgc ccggtgcggg
    10261 tgagagatga tgcgtcgacg ctgatgaggc ggtgcaccgt agacggcagt tgcaggggca
    10321 ccgacgcggg cggagtacgg tgctcagcga ccctggccca cacgtcccct tgttcgtacc
    10381 agtcctgccc ggcggcgcgg agcatgaacg tgggcagcag gagcgccagc tcccggcggc
    10441 gatcgcgctc ggcgtggacg gcgctcgcca ggtggtggag gatctgctgg ctgtcggtgt
    10501 gaaagagagc gtgggctacc gccatgccgt cagggccgcc gaaggcgtgc gactcgggct
    10561 cgtagaccac ctcggtcatg tctgctatat gcccggcgtg gacgagggct ctgaactggc
    10621 cgcggatgtc gcaccagatg ttggggtcgg cgggttggca gcggattctc cacgaggggg
    10681 tcttgcggat gaaaaaccac ggtgagaccg ccccgttggt gtcagcagct gccagaatcg
    10741 gggccaggtg gatgacggcg gtggtttcgg ctgtggcggg gtcggtgaag gcgacgttga
    10801 tctgccgcca ggagtctgtg ttcggcatcg ggcctctagg tgtgaaagcg acggctcagg
    10861 agagaagcag gaaggcatcc cagtcgggaa cgaccccggt tgcgaccgag tgcagggtca
    10921 aggcggcacc tgcggtgcca tccatgagct cgggctctgt atcggaccgg gccagttgct
    10981 cgatcaggtg gcgggtcagc tgtggaagtt cggcgtgaat gttcgacggg gtgagggcgt
    11041 cggcggcgat gcgccaggcg gattgcagta gtccggcggt gccgtggcac aggcccggtc
    11101 cgtcaaggcg atcgagttga tcgggatctt tgaacacggc caggatcgcc tcctccgcga
    11161 gctcctgacg ccgggcgtcg cggagcgcga ggcccgcgag ctgctgggcg cgtgcggccc
    11221 cggcgatgcc gtagcaccac gaaggccggg gcctcaggat gggatcgatg cgtcggatgt
    11281 ggtgctgatc gagggtgatc aacccgggcc accatgcggc tccgtcgctg cactggagcc
    11341 actggtctgt ccaggcgcag atccgcccga tcgcgtcgac gactccaggg accgcagcgc
    11401 cgcggatgac agatagggac aacaaggcca ggactcccgc gatcccatgt gagagaccga
    11461 agttgccgtg gccatccgga aaatcctgat cggactgtcc actggggccg gtcggcatcc
    11521 accaggacgg gagtccggca gtgccgccct tgggttcggt cagccgtacg aggtaggcga
    11581 ggacgtcacg ggtgacgtcg tggtcggggt ggcggcgaag gaggtggaca ccgagaccga
    11641 cgaggccgtg gatcaggtcg aactcccgca tcaacagcgc ttcgccgttg tcgatccgcc
    11701 tgtgggcatc ggtgaggcgt cgggtggtga tagcgacgac ggcgtcatcg agtttggcga
    11761 gagcaccttg gtaggcaggt gtgcgctccg acgcgatgtg caggagatag gcgagggtgg
    11821 gggcgccgaa gaacaggttc gcattgtcgg cggcactgac cggtccagcg gcggccaacc
    11881 gcagccaggt gtcggcggtt gctgggtcac cgtgaccggt gtgggcgcgg gtgatgtgca
    11941 gcagggccat tccggcggcg ccgccagcga gggactgcga gagtgtgcgc tggtcacgcg
    12001 gtggctgcgt tgggtccatg ccgggctttg cgagtgcctc ggagatggtc gaggctacgg
    12061 cgagagcgtc agtgtcgaat gtggagatgg tcatggcgtg ctccgtgccc ggcgcgtcca
    12121 gctcagggcg gcggcgcgtg ccaggtgcag gcatgcccgc tcggcgtccg agtcggcgcc
    12181 gtggatgcgc gtgaagtgaa gatgcagcag gtcagggagg aggctggaga ggctgatcgt
    12241 gctgtagtca gacagggcag cgcggtagct gtcgaggcct tggtggcgca accgccagga
    12301 cgagaggacc ggtttcccgc ctggcagggt ggccagttca tgtcggtcgg gggcggccag
    12361 agccacagcc tggtcgtaga ggtcgcgtgg gggtgctgtt cggtggcttc gggtgtggtc
    12421 gaccagccag tgcatcccgg cgacggaatc gcctccgttc gcggcgatcg cgaggtcgag
    12481 caggctggcg gcggtgacag cgcgtatgtc gatcgccgtg tcccgatcga gggtgagctg
    12541 cgtcagcgcc gcagcagaat cagcggcgaa gtagatctcg gcggcggtga gggcattctc
    12601 gccgccgaac cggttcgtct cggggaagtc ggtgtcgaag accatccggc tggccaggcc
    12661 ggcggtgcgc aaccgctgca tccaggcgtg gaccgatgct gtcgtttcgc cggaccggtc
    12721 tgccagagct tcgagtcgga gtcgcagatg cggttcgggg tcggcgtacc gcaggaacca
    12781 ccagcgggtc gcgggatcaa ggacgctgag aaggcgcggc aggtgatcgg tgagtatcgc
    12841 gtcgtgcagg ttcgcggcgc tgtagacctt cacgtaaagg ccgtccctgc ctccgggcgg
    12901 gcggccgtgc tcgcggacct gaaccactcg atcccggcct ggcggctggg gtggaccgtc
    12961 aacaccggaa ctggtggctg cgagcggtat gacgatctcg tggacgtgcc cgctggtcca
    13021 gccatcggcg tcgtcgggcg gcgcggcccg gagggtcgct tggccgaggc tttcgagatc
    13081 ggagcgcacc agctcgtggc aggccggttc ggtcaagtcg atgccgatac gccgatctcc
    13141 gtcaccgagg tacaccctgg ctggacaggc caccgtttcg cgccagtgct caactgcttc
    13201 cttgaaggtc tgggggttga ccggtcggcc cggcaactca tgcttcgaga cccgccagcg
    13261 cgccggtgcc agtagcgttc gtccgaaccg gacggccggc aggaacggga gtctcgcagc
    13321 tgcttggccc cactcgaatc cgtggcatgc ggtgcccagg gccccgggag cctcggtgag
    13381 gaaccgaaca agcgggaaca ggtaccggct cggttcaacg gcgttgaaca ggagcggttc
    13441 aaccactctg ccgtgggaca gccacaccag ccagagccgg tgcgcgtcgg cggtgacggc
    13501 gatgtcgtcg agcgccaggt gtgcgtggtg gcttggacgg agttcgccga gcaccagcag
    13561 gtgaggaagg acctgcgggg cgcgggcgac gttctccgtg gccgtgtacg gcaaggcggt
    13621 gcagacctga acaggaaggg ctccgcgggt gcgcatcggc atgctgccgt acgccgttgt
    13681 gaaggcgtcc cgatcggcgg agtcgagcag gtcgaggaac cgtccggtcg tggttcctgc
    13741 attgcgggac actccggtga tcgcgagcgt gaacgcaccc cggttcagtt cctcggtgcc
    13801 tcgggcatga acccgggcgg tgatctcggt gctcggctgc accccggcca ggccaggccg
    13861 tgtgtcaccc gccagttcgg cgatgagcgc ctcgtcgaga acgacctccc gctgcctccg
    13921 cagagccgcg tgctgtgcaa gggcgagcag ccgttcatcg cggctcgtga tggccgctcg
    13981 ccgaccaggc gggccgtcgc cgaacccgac ggggaacccc aagcccgtgc cttcgtcgac
    14041 ggcctgcgtg acggggacga gagcaccaag gccaaagcgc tcaaggaacc ggccgtgcca
    14101 ggccacccac tccggggccg gcggtcgggc caagcgcgtc agaaccgtcg cggctgccgc
    14161 ggcttcgaca gcgacgcttt ccggcacggt gaccttcgcg tcgagtttca ggtcgatggc
    14221 gacagcagat ccggcgatcg atgccacagc cgacgtgcat gcgtccaacc tggtgcgttc
    14281 ggtgtggcgc ccggccgggg tcgaggcgcg gtcctgtgtg acgacgattt ggcggatctc
    14341 gttgagcgac tccagaacca cagccgcctc cgggatgtcg gtggcaccgc aggcttccag
    14401 cgcctgagcg aggtgcgcga ggggatcggt gctcgtcatg gacggacgca gacttgtgat
    14461 cagcagccgc tgggacacca gagcgttgag aagcgcggcg accgaagcgg atggcgcctc
    14521 gtcgtaggcg gcggcgagct tgccttcgag ctcggcgacg ctgattggtt cagccgccat
    14581 ggcgatggcg gtacgagccg gactagtcgc gcgcacgctg acctggatcg ggctgtcctt
    14641 ggcagtcgtg cctgagcgcg tgagcaggag gcggccgtcg cgttcgacga tgaggttgtt
    14701 cgcggtgacc agcaactgtg atcggaccgc ggggatcgac tcaaggcggt cgatcaccgc
    14761 actcagccat gctgcctgga gacgtgccct gggctggtgc cgggtgccga ttaaggcgtg
    14821 accagcctgg gcaactcgcg cgggtgcgac gccagcgaac aacccgaacg gcgtggcgcg
    14881 accgctggca cgtaggaggt accgcaggac cgacagcact gcaccctgtg cgttcttggg
    14941 agagacctcg gcagcgtttc ggatcgcatc cacgcggccg gcgagtacgg gactggcctc
    15001 atacagcgct tcggcgaacc ctgggaggtc gagaaccttt tcgagccagt cgcgccaatc
    15061 cttcaccgtg gcagtcggtc ccaggttcgg ccagtgccca cgcgatgtag aggtgggcag
    15121 cgtcgcggcg cgcaccatga ggatctctag atatcgatac aagaccgtcg aacccccagc
    15181 agctgagaat cgaggcaggg ctcggtcagc ggcgatccac cgtgagcgag ccctgcctgg
    15241 ggcggtgaag cttcctgccg ggcggttacg ggcaggtggt gctgcaggcc gactggcagg
    15301 tctggccgca gccgtcgttg gtcatgtgga tcagccggtc ggcgttcgga ccggactcga
    15361 cgatcgtgat gtcgagatcc cagttgccga gatccttcac gctgacgtcg acggtttcga
    15421 tggtggatgt ggacatggtg gatctcctcg tgttgcggtg aagggtgacc aggaggcacc
    15481 ggaccggctc gagtaatcgg tccggtgggt ctatccccag gagacggtga tgcggccgtg
    15541 gttcttttgg gcctgccacg tcccggctgg gatgtcggtg agcgaggtgg ctgggagata
    15601 gccgatctgg gccgcgccgc gccgccgatg attggtggcc cagtcgcgga gcaactggag
    15661 gtaccgttcg gcaacctggt cggcgttcga accgtgggcg atgaccccgg actcgaaacc
    15721 gccgacagcg tcgttggctc gcttggtgcg gtaggcgaag ctgtcaccgt cgatcatgac
    15781 cggcacgccc cggccagccg aggccgcgaa cgctccgctc tcgacgagac cggcgctgac
    15841 gtgcaggagt ggaacgaccg gagcgctggt caccagaaac agctccagct catcgggaag
    15901 gtcgaaggcc gcgctcgacc agtactcccg tcggggagag tcgaaggccg ctcgcagacc
    15961 ggcaatgtcg agtttgggag cccgctcgtc gagacgaagc accgcatcgt cggtgacaga
    16021 cacgagagtc tcgttgaact ccccggcgcc ctggatagcc acgaaacccg acaggtagta
    16081 gttcacgctc gccaggccct cgctggtgcg atcgaaagcg atcgagcggg tcaggccggc
    16141 gaacctcagc gggacgacga tcctgccatc ggcagtgagc tggtcgagcc aggccggagg
    16201 aatgtcccac gccccgaccg tgacgatgat ccggtcgtag ggagcgttcg atgccacacc
    16261 atgctcggcg tcggccgtga ccacgtcgac ccgctcgtat ccggccgcat tgaggcagga
    16321 ccgggcgcgg tcggtgatgt cgggatcgat gtccaccgtc gtcacatggc cgtccgggcc
    16381 gacgagctcg gcaaggagtg ctgcgttgta gccacccgac ccgatctcca ggaccttcat
    16441 gccgggcgta atttcggcct gctccagcat cacggtctgg atcgccgtcg cagaaaggga
    16501 gctgaccgct ttcccatccg gggcccactt ggtcaccagc ggggtattcg gctcgtagac
    16561 ggcctccaga ggctcacccg gggcaaacaa atgccgaggt actgcggcca ccgcgtcgat
    16621 gaccggcggc gaccacagcg cctccatggc ctgtagttcc ctgatcatgt ccgctcggag
    16681 cacgccgggg tcgtgaacct gctgctctgg caatgtcgtc atgagaccgc ttccgattcg
    16741 cgagttgaga tgagatctgc tcgagttgtg ccgcgccact tggtatccac cgcgcgactc
    16801 tgatgccgat aacctgtggc tgcaccgcct caatccggcg gcgggatctt caccatacgg
    16861 aggagttttc gcccggttcg cacccgtcgt ccgctgccgc tgcagcgagg acatgcccgc
    16921 caggcgttgc tcaacggggc ggtgaaccgg cccttcccat cgcacttctt gcagggtttg
    16981 taaggccaga accagcagcc gaataagtag acggcgagca ggaccgcaag aatcagccac
    17041 gtccgagggt tggacagcaa cggttcgagg ccgttcaccg ggcaggctcc cgcggcgtcg
    17101 gacgctgatc cggcttgctt tcagtgggag aacacatgcc ttgagccaag cgcctcacac
    17161 gggctgttgg tagggctccg gtgcggacac aagggatgtc cgcatcactg gacgcggaac
    17221 gcgtgtacct gtcgcatggg cgaggagaat gaagacgggg cggctcgcga aggaggggat
    17281 cggtgggaca ggcacctaag gagctgacgc cgacggcgtc gccgctgcac ttcttcggcg
    17341 cgcagctccg cgaactgcgg gagactgccg gcttgtcgca agccgaactg ggccgagtga
    17401 ccctcaacag tgccgacctc gtgcgcaaga tcgagacggc ggagcgggcc gcatcacggc
    17461 agttcgtgga ccgctgtgac gaggtgctgt gcggaggcgg gatgctcagg cgcctctggc
    17521 cgcttctcga acgcgaacgc gagctccgtt ccaccattgc cgaccagcga gaccacggca
    17581 ctttagggcc atcggcccgt gccgaggatc gactggtgct tgactggctg ctcgcgcaca
    17641 acgcaggcga cgtaggccca gagccacctc agctcgacct cgccacgcat gccgcagagc
    17701 gcctgatgag gtttcgcgag gtcgaccacc tgcaaggggc cggccggacg tatccggaag
    17761 tcgccgacgt cgtacgacgc gatctgcaga agctgtcgca gaccgctccg tcggtggcga
    17821 tcggctacct cgaactagcc gggtatgaag ccgtcgatct cggcgccgac acccaggctc
    17881 gaggccacta cctacgggca ctggaaatca cgacgaggac cgggaaccgc ctctacggcg
    17941 gctacctgat cggcgtgagc ctggctcacc tggccttgca cggtggggac gcccggcacg
    18001 cgatccggtt ggtgaacgcg ggactgcgtg gtgtcgccga ctgcgccacc cctgcggtac
    18061 gtgccgcgat ccaagtcgtg gccgcgcggg cacatgcacg gctgggggat gagcgcgcca
    18121 gcgcggcggc tctgcaccag gtggacgtcg atttggaccg cagcaggccg gccgaggagc
    18181 ctgaatggat cggctacttc gggccggccg acttggctga cgaaaaggcg cactgcttct
    18241 tcgacctcgg gctccacgac cgtgcccagg acgaggcagc gaccgctatc gggctgttgc
    18301 acccgtcgag gatgcggcgg ttggcgatcg attcctccct gcacgcgaca tcgctggcac
    18361 gcagcggtga cctggatcgt gcctgtgccg tggcccacga agcgatcgac tacaccgccg
    18421 gcaccacgtc gttccgcagc gcccatcgcg tcaccatgat gctcgccgaa ctgcacccgc
    18481 acgccaccat ccccagcgtg cgagaagtca acgactacgc gaggactgtg ctcgccgacg
    18541 cgcctgtcag cctcgcggat ctgcccggtt gattactgcc tcgtaggcgg cgagttcagc
    18601 gctgagggcc gcgttcagtg cctcaggttt cgagagatag tgcccgacat cagccagagg
    18661 gaggtacccg gcgagcatcc cgcgggactt cagggcctcg gccagttcac gcacgtccgc
    18721 ggctggagca accatgtcgg cgtccccgtg aaccagcagg accggccgag acacacgatc
    18781 ggcctccact cctgcggtgg catgagtcaa gatcgccgcg tgcgggcgtt ggaagcgcgg
    18841 cgcggtctcg acccaccggt tggggtccac gatcgctgaa cgggcagccg ccagcgcgaa
    18901 tggcgtgtct ggggacgaca cggcacgcag tgcggtgtag ccgccagcgc tggccccggt
    18961 gatgaagatt gtgccgggtt cggcgagacc aagatcgatg aggcccaccg cggcgttgca
    19021 gcagtcggcc acatccagtt cgccccatcg atgatcgagc gtcttacgga aggcccggcc
    19081 gtacccggtg ctgccgccgt agtcgacgtc ggcgacagcg aagcctcggg atgtgaagaa
    19141 ctggatctcg gcgtcgagac ggagttcatt gtggtgggtc ggtcccggat gggcgcggac
    19201 tatcagtgga gctgcctggc ccggaacgca gctcagcggc gggtagtaga cgactgtgat
    19261 cggtactccg tcgctgtcga cccggaggat ctgcggagcg gacaccgcag cgtcagtagc
    19321 tggttcgggg ccgctgcgga tgacctcgat agcgccggat ccgtcggtgg ccaccagagc
    19381 tacctgttgc ggcactgtcg gtgaagaccc aatgaccgcg acgtggtcgc cgtacaccgc
    19441 gagatacggc ttgaagaacg tgtacggcgt cgccagtggc gtgaccgcac cggaggcttc
    19501 ggccaggacg aggcgatgtt ccaccccgtt ctgagcgacc atcgcgatcc ggccatccgg
    19561 aaggaaccca tagctggagt agcccagctc ccacagcgcc tcagcgcagt cggcttccat
    19621 cggcaccagg agctcgatcc cggcaccgtc ccagcgatga aggttctgcc atcccgatcc
    19681 ccggtcagac atgaagtaga gcgttccgtc tggcccccac tgcggctgcg ttgcggcctc
    19741 ggtcggccct ccagccacga gcgtggggtt cttcaactct tggccttgaa ccaagtcggc
    19801 gacccacacc tcggcctgat cccatggcat cacatcgact ggccactcca cccacgccaa
    19861 gcgtccgtcc gaaagcgacg gtgatgcgat gaacccggcg gtgcgcagga ctacctcacc
    19921 acctgaatcc gggtcgatga cgacgagttc gtcgtatgta tcggtttcac ggacaaacaa
    19981 caagagcccg ccggcgaacc gtagatctcc agcggaacca ggacttgtgt aggccgaacc
    20041 gccatccagc cagatccggc catcgtcact gctgaccacc cagatcccac gggggctgac
    20101 ggcgtacgtg cccccgccat aggcgtggat gctgttcccc accgggatgg tcgtgaaggt
    20161 cggaacctcc tgtggtgtcc acgtcgccac cacatccacg ccttgttcag gtctcgactc
    20221 gacccagaac atggctccat tgtgggccga gagtccatcg aaggagctcg ccgcgctggc
    20281 ctcggtggac tcggggagct cggcgcgtgt catcgcccca tccgatcaca tctggcctgg
    20341 catgaaccac ccggtcagca ggggatcgca gggacgtttc gaagcatcct tgaaaccctt
    20401 gtcgcgctgc tcaggtgcgc cgcagcaggt gggcggagat ttgaccatca gggccctcgg
    20461 cacgccgagg gccctgcgga cgctgatgcg gacagatgtg gcgtccgcat tcagagcctc
    20521 ccgaaacgac gtcgtgtgcg gccaaatgga gctaccgccc ctggaaggtc gcggaccttc
    20581 caggagatgt tgagggcaag gtccatgagt cgtgctcgat ttccacggct ggatgaagaa
    20641 cgaaggaagc agatgaccgt cgaagaaggt gtcgccgtgg acgatcccgg gctcgccgac
    20701 tgcgcagact gccaagggct cggtgcggcc ttcatgtcct gccaatgccg acgcgacgat
    20761 cagcgcacca gcgacttcat caggcgcgtg gggaacctgt tcggaatcgg ccgcagtgat
    20821 ggcccctgcc tgcagtgcaa cggagacgga gcgatcagcc accgctgcta ccggtgccag
    20881 ggcttcggcc gtgtccgagc ccaacttgtc tacgtcctga tcaacctcga cctcggcacc
    20941 atcgcttcca cagtgatcga acccggcgct ttcacgcccg tacgcatacc gaccggcggc
    21001 tggtgcattg atagcgaagt catagtcgac gagctcgctg cgcgcctcgg tgttgcccat
    21061 gtcgaagcgg ccgacggact cagtaagctg caagcgatcc ttctgccgaa ggagtggcgc
    21121 ccagacctcg atgactatga gcggctgaaa ctagaagcca cgacaatcgc cagggcaagc
    21181 ggactgggac gctggaagat cctgttcggc cggatggagg aacccgcccc actcgatgcc
    21241 gacagcacct tgactcagct gtgccgcctc gcctccgcct tgtgtctcga cctcgtcatc
    21301 gacaagcgac ggttcaggca cccaagagga aatccgggcg gctttcactg ggatgtgcgc
    21361 ttcgaaacct cgggcacgcc cgtggccgcg ccacgcaaaa tcggtggctc gtccagcctg
    21421 gcagaggcgc tcgctaaggc cgatccgctg aaactgctgg aaaacctgcc gcgttacgac
    21481 aggacggccc ctgcctaccg cctcgcccca gcggagccgc cagcagacct ggacctcagg
    21541 atcgcagcga tcgaagacga gctcaacacg accggtgaca gtccagtggg agccatcgcg
    21601 acctggtgcg actcgaggtg gcactacagt tcgttgcgtt cggtggccga gatagacggt
    21661 accgagttca tcgagcggat ccaatcacca ccgcggcccg cgtactgggc agaaccggtc
    21721 ttctcccgtg agtgccacgc atgcgccgac ggccctgagt accgctactg ccactgcgcc
    21781 atcgacggca acaaggccga cgccggctgc gtgtcctgcg caggcacagg catcaaggaa
    21841 tctcgcacgg gctgtttcac ctgcggcaaa gtcggtgaga tcagggcagg cgcggtcgtg
    21901 accatcaccg acctcgacca acaccacacc ttcatcgacc tgtcccctga cgctgacgcc
    21961 gagatcaccg acgcgggcct gacccccggc aacgccacca tctggcaact ccccgaccgc
    22021 tatcgactga gccactggct cagcacactc ggcatcccaa cggaccaggt catcgacccc
    22081 accggcgccg cgatgggagt ggacaaccat ctcgagcgtg gcagcgtcta cgacttccac
    22141 ggaacgatca ctactgccct cgatgccacc agcgcctacc ttgccgacat caccaaaggc
    22201 cgcaccggcg cgcgcatcat catcgtcgac agcacgccgg cctggcggcc actggaatcg
    22261 ctcgccgcca tcgccaccgg acttcagatg accctcgaag tcgtcgtgcg ctgctaccac
    22321 cactgcgaag gcgacatcgg cgccatccac ggtgaccttt ggggagtgca cctacgagcc
    22381 atcgatgcag cccccgacaa gttgaaccac gggcaccaca tcagcctccg agccgccgtc
    22441 aacgcctcct tcacttccct cggacagcaa ctttcgcgta cggcccgaga caccaacccc
    22501 accgtcgggc tgccggcccc tcagcaacct cacccaccgg tcaccgatct gaccggactc
    22561 gaacaagtca tgcacacgct cgccgagcgc tataccccac cgaccggcac gacaatcgcc
    22621 tgccgactga gccccggacg cgtcagcatc caccaccagc catcccacag cagcagaggc
    22681 ccgatgacga tcctcgccga aggccgggac ctcagcgaga tcgtgccctt gctcggccta
    22741 tagcccgaac ccgcagtaac gaagggaaac tccgtggcat ccatcgatga cctactcggt
    22801 tcgcttgaaa ccctcaaagg cgccatcgac caatccaaga gtgcagccaa cggcgcccgg
    22861 agcgtcgccg acgagaccta cagccagttc cagggcctgg gcgccgaggg ggtggccgcg
    22921 attctgaaca ccgccaagga tcagatcgag gccagcttca gcgccctcga ccaagccatg
    22981 aacgaagccg aacaggcgcg agccaccgca gagtcggcga agggctgagg ctgggagacg
    23041 cccgagccac gacgaggagc ccagacagga ctccttctgc accgagaggg agcccggcca
    23101 gccctccgtt gttcaagagc ggatccgtga ggtcgcaggc ggtctgaatg tgccgtccgg
    23161 gagatggccg ctggtctgac agtcgacgaa cagaaccgaa tgatcacgac caggaacgag
    23221 aacgctgtgc cccacaccgc ctggtggtcc tacgacagca ggacgcttga cagcccgaca
    23281 gacgtcgagg acctcttcgc caccgccacg acgacctggt actccaacgc cgtcaaagcc
    23341 attcggatac tgatcggccc ggctggcacc gacgagactc gggcacccct gcaagtcgac
    23401 atcgacatcg acgaaggccg tgcccacgtg cgttggcgcc ccgacgacac actcggtttc
    23461 gaggaaggcg ccaaacccca ccaccgttcc ttgcgggtcc atatccagtc cgatgagcca
    23521 ctcgcaacac ttgaaggggc agactgcctg gtgacgccgg gatacgcgct ccgcgcagtc
    23581 gaggagtaca ccgagacggg cgctcggcct ggatgtcttg gctggcgccc ctattgacct
    23641 ctgcggcggc aggcgagttc cgagagggcg ctcggtttac ccttctgcgg ttgcttcaat
    23701 gaagcccggc tgcttcctcc gggcgtcgta gccggcggcc tgcttgcggt agaggcgcgc
    23761 gtagagcccg ccgcgggcga ggagctcgtc atgggtgccg tggtcgctga tgcggccgtc
    23821 ttcgaggacg tagatggtgt cggcgtcccg gacgttggcc aggcggtggg taatcaagac
    23881 ggtggtgccg ctgcgttcgg cgaggtgggt gaacagcgcg tgctcggcgt cggcgtcgag
    23941 cgcggcggac ggttcgtcgc agatgaggat gggggcgtcg cggtaggcag tgcgggcggc
    24001 gaggagcctc tgccattggc cgccggagag gtcgtgtccg cctttgaagg tgcggtcgag
    24061 cagggtcgcg tagcccttgg ggaagtcgag gatcatgtcg tgggcgccgg tggctttggc
    24121 agcttcggtg atcttggccg ggaccttcga gccgttgacg cggtcgttgg cggtgatgtc
    24181 gccgatcttg atgttcatgg tcgctgtcag cggccactgc tggaaatcct gccgcatcac
    24241 gccgacgtgc cgggcgacca cgtcagcatc gagatcggcc agatcggttg cgtcccaggt
    24301 gatgcgtcct gaagtggggg tgtacaaccc cgcaagaagc gcggcgaggg tggtctttcc
    24361 ggacccgttc ttacccacca gcgcgatcgt ttccccacgc ctgaccgtga gagtgacgcc
    24421 cgcgagggcg tccttttcgg tgctggggta ccggaacgtc acgtcttcga cggcgattac
    24481 atccggtgcc ttaggccgct gagggcttct ggggcgaggg attcggcctc ggccggtggc
    24541 tatgaacgct tggtggtctg cggcgtacaa accctggtcg aacagcgcat tgatcgacat
    24601 gaccaggagg ttcacatcgc ccctgccgcg ctgaagggcc agcacggccg tggccgccgc
    24661 ggcgagggcc accgcgccga tcgcgatcag ccagcccagt ccggcataca tcgccaacgc
    24721 ggccgcgccg ccgatgagtc caccgacgac gcggatccgg gtctgggagg ccagcaccga
    24781 catgtccgtg tcggtttcga cccgcatgat cttgccatgc tctccgcgca gccacgccga
    24841 cagaccgagc gtgcggacct cggcggcggt gttgcgggag gccatgaggg tttccaggac
    24901 ccacacgcgt cgtcgcctgg cggcccgctg gtaccaggag gtgtactcca cgcgcgcagc
    24961 gcgcaccgct gcccatccgg ccggcagccc tgctgcgagt aggaacacca gtagcagtgg
    25021 gtggatcacc acgagcaccg cggccacggc ggcgaccccg acgagcccgg tgaggacgtc
    25081 gacagactcc tgcaccaacc gcaccatcgc ctggatgccc cgcgacttcg acttgtcc
//
