LOCUS       NZ_JACICH010000010     10843 bp    DNA     linear   CON 07-MAY-2024
DEFINITION  Xanthomonas euroxanthea strain 2974 Ga0372488_10, whole genome
            shotgun sequence.
ACCESSION   NZ_JACICH010000010
VERSION     NZ_JACICH010000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Xanthomonas euroxanthea
  ORGANISM  Xanthomonas euroxanthea
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Xanthomonas.
REFERENCE   1  (bases 1 to 10843)
  AUTHORS   Potnis,N.
  TITLE     Studying the diversity of plant-associated saprophytic bacteria and
            their role in host health and plant-pathogen interactions
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10843)
  AUTHORS   Potnis,N., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2020) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 312.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014195725.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 06:44:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,037
            CDSs (total)                      :: 3,960
            Genes (coding)                    :: 3,887
            CDSs (with protein)               :: 3,887
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 22
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 27 of 73
            Pseudo Genes (incomplete)         :: 55 of 73
            Pseudo Genes (internal stop)      :: 9 of 73
            Pseudo Genes (multiple problems)  :: 16 of 73
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:54:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 10843
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JACICH010000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..10843
                     /country="USA"
                     /db_xref="taxon:2259622"
                     /isolation_source="Rain"
                     /mol_type="genomic DNA"
                     /organism="Xanthomonas euroxanthea"
                     /strain="2974"
                     /submitter_seqid="Ga0372488_10"
     region          1..10843
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..10843
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10843
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[11:>10843](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      12..>10843
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            12..3239
                     /locus_tag="FHY13_RS19945"
                     /old_locus_tag="FHY13_004081"
     CDS             12..3239
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: PCP (123-187). E-value: 3.7e-24. Score:
                     76.7. Matches aSDomain: nrpspksdomains_FHY13_RS19945_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (220-524). E-value:
                     6.6e-54. Score: 175.0. Matches aSDomain:
                     nrpspksdomains_FHY13_RS19945_Condensation_DCL.1"
                     /NRPS_PKS="Domain: PCP (964-1033). E-value: 3.6e-18. Score:
                     57.5. Matches aSDomain: nrpspksdomains_FHY13_RS19945_PCP.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="FHY13_RS19945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHY13_004081"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_260222257.1"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-11, bitscore:
                     31.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.6e-16, bitscore:
                     46.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.8e-49, bitscore:
                     156.5, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEYLGRDDAQVKVRGYRIELGEVERALASHPQLGAVSVQAHDAG
                     EGKRLVAYVVALPGNTVPGTGELQRYLGEWVPEYMVPALYVGLDRLPLTANGKIDKAAL
                     PKPGAARAADTHEAPQGEVEQALAQIWAQVLDVAQVGRHDNFFELGGDSILSIQIKAQA
                     QQQGLEFALEALFERQTVARLAEVTTPRDPAIHAATKSIAPFALVDADMRARLPAGIED
                     AYPLSHMQAGMLFHNAYAAQSPTYHDVIRYTVGTSFDRDRFVAALRTVVARHPALRTRF
                     SIADYELPLQCVYRHVEPELEIEDASDLSLEAQEALINAWVDQEHVIGFRGENPQWIRY
                     YVCVLGERGFALGLSFHHALMDGWSEASLVTELLGLHHGASFTTAARPLRSAYRDYIDA
                     ELRALADEEARAFWKDEVARSAPAVIAPDLNLVQDEDPGGLVAGKTILHAEIAISQHTS
                     DRLFALAARLQVPPRTVLLAVHSTAMAIATGQDTVTSGLIAHGRLDHLDGDAVLGVFLN
                     ALPFTQQVAGERWADAIRITFTHEQAVERHRRFPVASLTQSAGARLPFDVLFNFTKFHV
                     YERLDAGQPRLDLGQRGGIAETSLPLCVNFQVDPQGQSVRGGLSFLAERYSARAARGVA
                     HIYARILDTLDAYGEAARPTSWGDLAGSAERGLPLSDALAATAGQIAAVPALRVGSESV
                     CHRDLDARIAAVATALRRRGVGPGSSVELDIHDPAQRLMALLGILKAGAEAIPQVAASP
                     GGLLRIALTPETTSAIPTVTLQALLAVPVAGDSVRVDTDTELQIVDRHGCAVPPGVIGE
                     LCLYDASIVMGEERRAYRSGLLARLLPDGSLEWLGACVQRIRHRSFGIVPAEIEHCLVV
                     HAQVSDVVVRKVTGPDHEHLVAFVVPAAAGSPPDWQELRRHAAQTLPPHHVPDHYLALD
                     CLPFDATGQLDDVALRLVAGGQAACEDEAPVGDLETVLASLWSDVLGIAAIGRHTDFFQ
                     ISGDSIQAMQITARVEKTLAVLAPVGLMYANPTIAEFAAALRDDPNSGRRVMRAAELLV
                     RLATERHALPPAGDPVRDEARLMEAKE"
     CDS_motif       21..86
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19945_0001"
                     /evalue="3.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="FHY13_RS19945"
                     /protein_end="25"
                     /protein_start="3"
                     /score="35.1"
                     /tool="antismash"
                     /translation="YLGRDDAQVKVRGYRIELGEVE"
     aSDomain        381..572
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FHY13_RS19945_PCP.1"
                     /evalue="3.70E-24"
                     /label="FHY13_RS19945_PCP.1"
                     /locus_tag="FHY13_RS19945"
                     /protein_end="187"
                     /protein_start="123"
                     /score="76.7"
                     /tool="antismash"
                     /translation="EQALAQIWAQVLDVAQVGRHDNFFELGGDSILSIQIKAQAQQQGL
                     EFALEALFERQTVARLAEV"
     CDS_motif       444..473
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19945_0002"
                     /evalue="4.30E-02"
                     /label="PCP_mE"
                     /locus_tag="FHY13_RS19945"
                     /protein_end="154"
                     /protein_start="144"
                     /score="6.9"
                     /tool="antismash"
                     /translation="NFFELGGDSI"
     aSDomain        672..1583
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FHY13_RS19945_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="6.60E-54"
                     /label="FHY13_RS19945_Condensation_DCL.1"
                     /locus_tag="FHY13_RS19945"
                     /protein_end="524"
                     /protein_start="220"
                     /score="175.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHALMDG"
                     /tool="antismash"
                     /translation="EDAYPLSHMQAGMLFHNAYAAQSPTYHDVIRYTVGTSFDRDRFVA
                     ALRTVVARHPALRTRFSIADYELPLQCVYRHVEPELEIEDASDLSLEAQEALINAWVDQ
                     EHVIGFRGENPQWIRYYVCVLGERGFALGLSFHHALMDGWSEASLVTELLGLHHGASFT
                     TAARPLRSAYRDYIDAELRALADEEARAFWKDEVARSAPAVIAPDLNLVQDEDPGGLVA
                     GKTILHAEIAISQHTSDRLFALAARLQVPPRTVLLAVHSTAMAIATGQDTVTSGLIAHG
                     RLDHLDGDAVLGVFLNALPFTQQ"
     aSModule        672..3110
                     /domains="nrpspksdomains_FHY13_RS19945_Condensation_DCL.1"
                     /domains="nrpspksdomains_FHY13_RS19945_PCP.2"
                     /incomplete
                     /locus_tags="FHY13_RS19945"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       681..722
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19945_0003"
                     /evalue="1.70E-04"
                     /label="C1_DCL_004-017"
                     /locus_tag="FHY13_RS19945"
                     /protein_end="237"
                     /protein_start="223"
                     /score="13.7"
                     /tool="antismash"
                     /translation="YPLSHMQAGMLFHN"
     CDS_motif       747..854
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19945_0004"
                     /evalue="6.10E-10"
                     /label="C2_LCL_024-062"
                     /locus_tag="FHY13_RS19945"
                     /protein_end="281"
                     /protein_start="245"
                     /score="31.5"
                     /tool="antismash"
                     /translation="YHDVIRYTVGTSFDRDRFVAALRTVVARHPALRTRF"
     CDS_motif       1077..1136
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19945_0005"
                     /evalue="1.20E-06"
                     /label="C3_DCL_135-156"
                     /locus_tag="FHY13_RS19945"
                     /protein_end="375"
                     /protein_start="355"
                     /score="21.1"
                     /tool="antismash"
                     /translation="FHHALMDGWSEASLVTELLG"
     aSDomain        2904..3110
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FHY13_RS19945_PCP.2"
                     /evalue="3.60E-18"
                     /label="FHY13_RS19945_PCP.2"
                     /locus_tag="FHY13_RS19945"
                     /protein_end="1033"
                     /protein_start="964"
                     /score="57.5"
                     /tool="antismash"
                     /translation="ETVLASLWSDVLGIAAIGRHTDFFQISGDSIQAMQITARVEKTLA
                     VLAPVGLMYANPTIAEFAAALRDD"
     CDS_motif       2967..2996
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19945_0006"
                     /evalue="3.80E+00"
                     /label="PCP_mE"
                     /locus_tag="FHY13_RS19945"
                     /protein_end="995"
                     /protein_start="985"
                     /score="1.8"
                     /tool="antismash"
                     /translation="DFFQISGDSI"
     gene            3236..7990
                     /locus_tag="FHY13_RS19950"
                     /old_locus_tag="FHY13_004082"
     CDS             3236..7990
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (34-327). E-value:
                     7.5e-63. Score: 204.3. Matches aSDomain:
                     nrpspksdomains_FHY13_RS19950_Condensation_LCL.1"
                     /NRPS_PKS="Domain: PCP (922-986). E-value: 1.3e-17. Score:
                     55.7. Matches aSDomain: nrpspksdomains_FHY13_RS19950_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1016-1311). E-value:
                     2.4e-58. Score: 189.6. Matches aSDomain:
                     nrpspksdomains_FHY13_RS19950_Condensation_DCL.1"
                     /NRPS_PKS="Domain: PCP (1481-1550). E-value: 2.7e-15.
                     Score: 48.3. Matches aSDomain:
                     nrpspksdomains_FHY13_RS19950_PCP.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="FHY13_RS19950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHY13_004082"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_184364035.1"
                     /sec_met_domain="Condensation (E-value: 4e-49, bitscore:
                     155.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-14, bitscore:
                     41.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.8e-14, bitscore:
                     40.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRITSQDQEAVARLLAEEGLLESAPPVVRVTDAHRAPLSDYQYS
                     LWLALNGGGARHANVPLVLKISGGTLEGAVLEQALVSIAEQHEALRCLIVVEDEVAWQV
                     PQPLHRLRLRMERVDAGSLDARIDALVNAPLDIRTELPYRLHLLQVDAALSYLVVVTHH
                     LVFDGWSLVLLQDELQMRYAQLLRGAALPPPSLKPRHLDFALWQASDAGQASRQKGLEH
                     WRRLLQGARSRLHWMGVSRGQGTFAQAGGNFLSELPQPLSAKVHAFAAAHRTTVFVVMV
                     SVYVEVLSRFCLQDDLCVGTPTSARDQLDLEKMIGYFVNTLLLRHQREPWQSFIDLLRR
                     MDAQFRLAREHQAVPFHAVTRALEGVRGSQQPFTQAMFAYQTESSGTGLGFQSGGLAFE
                     PYPCELNEARYDLLLTVLSKHRQLAINIEYRAHLFGIRTIAQFADAYLRLLDAAITNPS
                     ARLAELGVEAPFALQAVAPTMASLARPASAEGRQRLASLVRILAAVGIGCRSRVGLAGQ
                     PCEAQAQVLLALLDRGACCVVLDAQTVVDGGPGYAEQMGVQIIVTDGTWQAALQGVVAT
                     VLDVEHLVDAGGDAPVSKFALSQLVRVEAGPEGAAPGQIVFPAEAIIAGLSATGCLTNL
                     AGWGSDPHAPVFDRVMVQLAQCMSADIGTPQVRVDGIPLRSDEGAGQVLHRLGFGDLDA
                     PRRLHAEGSVDYRYLLRVPERIVDGSICHVRSGASSRFDIASAVLLDRHAGPVDAGMPG
                     ELLLGGAALAWGYAGDARRTAEHFIPDPAAPHPGARLLRTGAWASHDPDGGLRLLGHEQ
                     LRVDHQGVVFDLAEVECELLALDGVVAARAQRDDESGRGAISVSLVLDGGHTYSAVALR
                     EHLAPRLPGKALPSRFLVTAAPIRGVDMGIEPAAFQVLLAQDGTDPALERIEAILLEVW
                     QQTLDCVVHRDDNFFELGGDSMLCLVVQSRAAKREVQFAVEDLFAHQTLAALAAHCHHG
                     VVRNQDVGPFDLVAPEDRVHLPADAEAAYPMSRLQAGMFYHSRDASQRLYFDVVHVWLE
                     GNANVPLLRDCLQGVLAQADTCRSTFHITGYSEPLQIVRRDRSVPIELIDAAASEDAQM
                     QSCIEAWTQDDLARGFDMERHAPIRCAIHRFSDTRSVMSYSFHHALLDGWSEAQITVDT
                     LSLYAQCRAGQERPVAAPRLRYREFIALERAAETSTAQRSFWQAYLQDVHCRDIPVIQG
                     AETEDLAGALELPLCATRSAQLQALAASLKVSIKAVLLAVHCHVMAMVTGSPDVITGVP
                     FNGRPELAGGAQALGLFLNTLPLRVRTDRCHHWRSLVAASARSEAEMAPYRRFPLSAVI
                     AATGEVARPKVLFNYLHFHNYDTLDETLPLQMTARTGVAVNSLSYVVNFWTDPGEKRIF
                     GMLSVPAQEREHGRQIAALFEHCIASIADSPNSVLPEPPLGYAAYRDTARTAGISNGDG
                     GSGGESAAIVDRGGAPQSPTEHVVASVWRKVLGIDDVQRNDEFNALGGDSIAAMRVVAE
                     LERIYECDIDMATILLFPRLATFCAALDRDATYGEDIITSSRLLMEAYRARLRRDAAPR
                     SGAGA"
     aSDomain        3338..4216
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FHY13_RS19950_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="7.50E-63"
                     /label="FHY13_RS19950_Condensation_LCL.1"
                     /locus_tag="FHY13_RS19950"
                     /protein_end="327"
                     /protein_start="34"
                     /score="204.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLVFDG"
                     /tool="antismash"
                     /translation="HRAPLSDYQYSLWLALNGGGARHANVPLVLKISGGTLEGAVLEQA
                     LVSIAEQHEALRCLIVVEDEVAWQVPQPLHRLRLRMERVDAGSLDARIDALVNAPLDIR
                     TELPYRLHLLQVDAALSYLVVVTHHLVFDGWSLVLLQDELQMRYAQLLRGAALPPPSLK
                     PRHLDFALWQASDAGQASRQKGLEHWRRLLQGARSRLHWMGVSRGQGTFAQAGGNFLSE
                     LPQPLSAKVHAFAAAHRTTVFVVMVSVYVEVLSRFCLQDDLCVGTPTSARDQLDLEKMI
                     GYFVNTLLLRHQ"
     aSModule        3338..6193
                     /domains="nrpspksdomains_FHY13_RS19950_Condensation_LCL.1"
                     /domains="nrpspksdomains_FHY13_RS19950_PCP.1"
                     /incomplete
                     /locus_tags="FHY13_RS19950"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3410..3511
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19950_0001"
                     /evalue="1.00E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="FHY13_RS19950"
                     /protein_end="92"
                     /protein_start="58"
                     /score="14.7"
                     /tool="antismash"
                     /translation="NVPLVLKISGGTLEGAVLEQALVSIAEQHEALRC"
     CDS_motif       3719..3781
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19950_0002"
                     /evalue="1.70E-07"
                     /label="C3_LCL_132-143"
                     /locus_tag="FHY13_RS19950"
                     /protein_end="182"
                     /protein_start="161"
                     /score="23.8"
                     /tool="antismash"
                     /translation="HHLVFDGWSLVLLQDELQMRY"
     CDS_motif       4121..4210
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19950_0003"
                     /evalue="4.90E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="FHY13_RS19950"
                     /protein_end="325"
                     /protein_start="295"
                     /score="41.4"
                     /tool="antismash"
                     /translation="DLCVGTPTSARDQLDLEKMIGYFVNTLLLR"
     CDS_motif       4277..4375
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19950_0004"
                     /evalue="4.20E-04"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="FHY13_RS19950"
                     /protein_end="380"
                     /protein_start="347"
                     /score="12.6"
                     /tool="antismash"
                     /translation="AREHQAVPFHAVTRALEGVRGSQQPFTQAMFAY"
     CDS_motif       5483..5566
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19950_0005"
                     /evalue="6.20E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="FHY13_RS19950"
                     /protein_end="777"
                     /protein_start="749"
                     /score="28.2"
                     /tool="antismash"
                     /translation="GMPGELLLGGAALAWGYAGDARRTAEHF"
     aSDomain        6002..6193
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FHY13_RS19950_PCP.1"
                     /evalue="1.30E-17"
                     /label="FHY13_RS19950_PCP.1"
                     /locus_tag="FHY13_RS19950"
                     /protein_end="986"
                     /protein_start="922"
                     /score="55.7"
                     /tool="antismash"
                     /translation="EAILLEVWQQTLDCVVHRDDNFFELGGDSMLCLVVQSRAAKREVQ
                     FAVEDLFAHQTLAALAAHC"
     CDS_motif       6062..6091
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19950_0006"
                     /evalue="2.20E-01"
                     /label="PCP_mE"
                     /locus_tag="FHY13_RS19950"
                     /protein_end="952"
                     /protein_start="942"
                     /score="5.1"
                     /tool="antismash"
                     /translation="NFFELGGDSM"
     aSDomain        6284..7168
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FHY13_RS19950_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="2.40E-58"
                     /label="FHY13_RS19950_Condensation_DCL.1"
                     /locus_tag="FHY13_RS19950"
                     /protein_end="1311"
                     /protein_start="1016"
                     /score="189.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHALLDG"
                     /tool="antismash"
                     /translation="AYPMSRLQAGMFYHSRDASQRLYFDVVHVWLEGNANVPLLRDCLQ
                     GVLAQADTCRSTFHITGYSEPLQIVRRDRSVPIELIDAAASEDAQMQSCIEAWTQDDLA
                     RGFDMERHAPIRCAIHRFSDTRSVMSYSFHHALLDGWSEAQITVDTLSLYAQCRAGQER
                     PVAAPRLRYREFIALERAAETSTAQRSFWQAYLQDVHCRDIPVIQGAETEDLAGALELP
                     LCATRSAQLQALAASLKVSIKAVLLAVHCHVMAMVTGSPDVITGVPFNGRPELAGGAQA
                     LGLFLNTLPLRVRT"
     aSModule        6284..7885
                     /domains="nrpspksdomains_FHY13_RS19950_Condensation_DCL.1"
                     /domains="nrpspksdomains_FHY13_RS19950_PCP.2"
                     /incomplete
                     /locus_tags="FHY13_RS19950"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6350..6460
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19950_0007"
                     /evalue="1.00E-03"
                     /label="C2_LCL_024-062"
                     /locus_tag="FHY13_RS19950"
                     /protein_end="1075"
                     /protein_start="1038"
                     /score="11.5"
                     /tool="antismash"
                     /translation="YFDVVHVWLEGNANVPLLRDCLQGVLAQADTCRSTFH"
     CDS_motif       6680..6715
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19950_0008"
                     /evalue="1.40E-04"
                     /label="C3_DCL_135-156"
                     /locus_tag="FHY13_RS19950"
                     /protein_end="1160"
                     /protein_start="1148"
                     /score="14.6"
                     /tool="antismash"
                     /translation="FHHALLDGWSEA"
     CDS_motif       7067..7159
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19950_0009"
                     /evalue="1.00E-08"
                     /label="C5_DCL_263-294"
                     /locus_tag="FHY13_RS19950"
                     /protein_end="1308"
                     /protein_start="1277"
                     /score="27.7"
                     /tool="antismash"
                     /translation="DVITGVPFNGRPELAGGAQALGLFLNTLPLR"
     aSDomain        7679..7885
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FHY13_RS19950_PCP.2"
                     /evalue="2.70E-15"
                     /label="FHY13_RS19950_PCP.2"
                     /locus_tag="FHY13_RS19950"
                     /protein_end="1550"
                     /protein_start="1481"
                     /score="48.3"
                     /tool="antismash"
                     /translation="EHVVASVWRKVLGIDDVQRNDEFNALGGDSIAAMRVVAELERIYE
                     CDIDMATILLFPRLATFCAALDRD"
     CDS_motif       7742..7771
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19950_0010"
                     /evalue="1.90E+00"
                     /label="PCP_mE"
                     /locus_tag="FHY13_RS19950"
                     /protein_end="1512"
                     /protein_start="1502"
                     /score="2.6"
                     /tool="antismash"
                     /translation="EFNALGGDSI"
     gene            7987..8802
                     /locus_tag="FHY13_RS19955"
                     /old_locus_tag="FHY13_004083"
     CDS             7987..8802
                     /NRPS_PKS="Domain: Thioesterase (39-260). E-value: 2.5e-33.
                     Score: 108.4. Matches aSDomain:
                     nrpspksdomains_FHY13_RS19955_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.4"
                     /locus_tag="FHY13_RS19955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHY13_004083"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_184364038.1"
                     /sec_met_domain="Thioesterase (E-value: 1.8e-33, bitscore:
                     104.7, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3e-11, bitscore:
                     32.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISAESIATLHSSPARLAAATTYPADVMVRLWGGDQGVPLFLVH
                     PVGGGVGCYLPLVQALKPTYPVYALRHPGLNGESPRQALDDLAQRYLDAILSVQRGRPY
                     RLGGWSLGGVIAALMAARAEALEEPPSLLLVIDSPACAADGSFVHVESSSGPDEDEDQR
                     ALLQEMERNAAALHGDHDALAVLRAVLAANAEALSVYRMTATVRAVHYIGAGSDLSDRG
                     WRALASERFERRQCTGNHYSMMDAPHVSMLARHCAEWLAPRTIVTTGDA"
     CDS_motif       8104..8133
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19955_0001"
                     /evalue="1.80E-03"
                     /label="NRPS-beforete1"
                     /locus_tag="FHY13_RS19955"
                     /protein_end="49"
                     /protein_start="39"
                     /score="11.3"
                     /tool="antismash"
                     /translation="PLFLVHPVGG"
     aSDomain        8104..8766
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FHY13_RS19955_Thioesterase.1"
                     /evalue="2.50E-33"
                     /label="FHY13_RS19955_Thioesterase.1"
                     /locus_tag="FHY13_RS19955"
                     /protein_end="260"
                     /protein_start="39"
                     /score="108.4"
                     /tool="antismash"
                     /translation="PLFLVHPVGGGVGCYLPLVQALKPTYPVYALRHPGLNGESPRQAL
                     DDLAQRYLDAILSVQRGRPYRLGGWSLGGVIAALMAARAEALEEPPSLLLVIDSPACAA
                     DGSFVHVESSSGPDEDEDQRALLQEMERNAAALHGDHDALAVLRAVLAANAEALSVYRM
                     TATVRAVHYIGAGSDLSDRGWRALASERFERRQCTGNHYSMMDAPHVSMLARHCAEWL"
     CDS_motif       8290..8352
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19955_0002"
                     /evalue="1.60E-10"
                     /label="NRPS-te1"
                     /locus_tag="FHY13_RS19955"
                     /protein_end="122"
                     /protein_start="101"
                     /score="33.4"
                     /tool="antismash"
                     /translation="RPYRLGGWSLGGVIAALMAAR"
     gene            8808..>10843
                     /locus_tag="FHY13_RS19960"
                     /old_locus_tag="FHY13_004084"
     CDS             8808..>10843
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (32-331). E-value:
                     3.8e-86. Score: 280.7. Matches aSDomain:
                     nrpspksdomains_FHY13_RS19960_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="FHY13_RS19960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FHY13_004084"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_184364041.1"
                     /sec_met_domain="Condensation (E-value: 1.8e-59, bitscore:
                     189.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.6e-33, bitscore:
                     102.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDITDLDLKLLNAHRRSRRSEERAGIVLQPGDQGPLSFAQSRMAY
                     LQLCDPASSQYNMPFAFRVDGTLDRAALLQAIAWLLDRHSVLRSGVHLVDGEPVQRIHP
                     TGEVRIDECNLSDLPSQVAEDALRTWMGERVRVPFALDAGCMLRTELALLPGEQTLVLL
                     TMHHIASDGWSLGILKAELSAAYAAFAQGTVPVLPALPIRYLDFAAWEQRNAERDAERH
                     FAYWQRQLAEVDTLATLVHDRPRGAGIGSPGSTVALALGCRSSASLRELARQEGATGYA
                     VAASAFAVVLSRMGNAAVVQFGTPTANRIRAETQGLIGFFVNMLVIRLQVRGDASFRSL
                     VRAARQTVAEAQSHQSVPYEQLVERLQGTSRPQRNGLFQVVFSYDAMAAVTAPMRFGPH
                     VAVADVAPHQTAKFDLTVNMVESGDELLLVAEYASDVFERARIEAICAQYRDTLEAVLS
                     APDVALAALFAPAQLQEALPVARHCSADLFARLQAHPPQAIALQGETVLDYATLLAKVE
                     RLAVRLRLRGQGPGSVVGLLIEERATLIVAMLACLRAGVAFLMLDAGYPATRLRYMLDS
                     GRSRFLLRQGAVPPLTALQVLDLDAPDSDAVGTPGPVTDGAVSSILHTSGSTGEPKAVA
                     LPVSGLIQHALRMQQLWQLGPDDRVLQFNSPAFDAFLEEVFTTL"
     aSDomain        8904..9800
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FHY13_RS19960_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.80E-86"
                     /label="FHY13_RS19960_Condensation_LCL.1"
                     /locus_tag="FHY13_RS19960"
                     /protein_end="331"
                     /protein_start="32"
                     /score="280.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIASDG"
                     /tool="antismash"
                     /translation="QGPLSFAQSRMAYLQLCDPASSQYNMPFAFRVDGTLDRAALLQAI
                     AWLLDRHSVLRSGVHLVDGEPVQRIHPTGEVRIDECNLSDLPSQVAEDALRTWMGERVR
                     VPFALDAGCMLRTELALLPGEQTLVLLTMHHIASDGWSLGILKAELSAAYAAFAQGTVP
                     VLPALPIRYLDFAAWEQRNAERDAERHFAYWQRQLAEVDTLATLVHDRPRGAGIGSPGS
                     TVALALGCRSSASLRELARQEGATGYAVAASAFAVVLSRMGNAAVVQFGTPTANRIRAE
                     TQGLIGFFVNMLVIRLQV"
     CDS_motif       8970..9077
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19960_0001"
                     /evalue="2.10E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="FHY13_RS19960"
                     /protein_end="90"
                     /protein_start="54"
                     /score="45.8"
                     /tool="antismash"
                     /translation="QYNMPFAFRVDGTLDRAALLQAIAWLLDRHSVLRSG"
     CDS_motif       9300..9365
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19960_0002"
                     /evalue="1.60E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="FHY13_RS19960"
                     /protein_end="186"
                     /protein_start="164"
                     /score="36.5"
                     /tool="antismash"
                     /translation="MHHIASDGWSLGILKAELSAAY"
     CDS_motif       9417..9446
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19960_0003"
                     /evalue="2.20E-02"
                     /label="C4_LCL_164-176"
                     /locus_tag="FHY13_RS19960"
                     /protein_end="213"
                     /protein_start="203"
                     /score="7.8"
                     /tool="antismash"
                     /translation="YLDFAAWEQR"
     CDS_motif       9474..9497
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19960_0004"
                     /evalue="1.40E-01"
                     /label="C4_LCL_164-176"
                     /locus_tag="FHY13_RS19960"
                     /protein_end="230"
                     /protein_start="222"
                     /score="5.3"
                     /tool="antismash"
                     /translation="FAYWQRQL"
     CDS_motif       9711..9791
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19960_0005"
                     /evalue="7.60E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="FHY13_RS19960"
                     /protein_end="328"
                     /protein_start="301"
                     /score="44.0"
                     /tool="antismash"
                     /translation="FGTPTANRIRAETQGLIGFFVNMLVIR"
     CDS_motif       9840..9959
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19960_0006"
                     /evalue="9.80E-15"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="FHY13_RS19960"
                     /protein_end="384"
                     /protein_start="344"
                     /score="46.9"
                     /tool="antismash"
                     /translation="RQTVAEAQSHQSVPYEQLVERLQGTSRPQRNGLFQVVFSY"
     CDS_motif       10452..10493
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19960_0007"
                     /evalue="2.70E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="FHY13_RS19960"
                     /protein_end="562"
                     /protein_start="548"
                     /score="11.3"
                     /tool="antismash"
                     /translation="LACLRAGVAFLMLD"
     CDS_motif       10668..10715
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FHY13_RS19960_0008"
                     /evalue="2.30E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="FHY13_RS19960"
                     /protein_end="636"
                     /protein_start="620"
                     /score="17.1"
                     /tool="antismash"
                     /translation="ILHTSGSTGEPKAVAL"
ORIGIN
        1 gcagcgacgg catgctggag tatctgggcc gcgacgatgc gcaggtgaag gtgcgcggtt
       61 accggatcga actgggagaa gtggagcgtg cgctggccag ccatccccag ttgggtgcgg
      121 tgagcgtgca ggcacacgac gctggcgagg gcaagcggct ggtggcgtat gtggtggcac
      181 tgccgggcaa tacggtgccg gggacaggcg agctgcagcg ctacctcggt gagtgggtgc
      241 cggagtacat ggtgccggcg ttgtacgtgg gcctggaccg gctgccgctg acggccaacg
      301 ggaagatcga caaggcggcg ttgccgaaac cgggcgctgc gcgtgctgcc gacacgcacg
      361 aggcgcccca gggcgaggtg gaacaggcgc tggcgcagat ctgggcgcag gtgctggacg
      421 ttgcgcaggt ggggcggcat gacaacttct tcgagctggg cggcgattcg atcctgagca
      481 tccagatcaa ggcgcaggcg cagcaacaag ggctggagtt tgcgctggag gcgttgttcg
      541 aacgccagac cgtggccagg ctggccgagg tgacgacgcc gcgtgatcca gccatccacg
      601 ccgccaccaa gtccatcgcg ccctttgcac tggtggatgc cgatatgcgt gcacggttac
      661 ccgcgggtat cgaggatgcg tatccgctca gtcacatgca ggcgggcatg ttgttccaca
      721 acgcctatgc cgcgcagtcg ccgacctatc acgatgtgat ccggtacacg gttggaacgt
      781 cgttcgaccg cgatcgtttc gtggctgccc tgcgtacggt agtggcacgg catccagcgt
      841 tgcgcacgcg tttcagcatc gccgattacg aactgccgct gcagtgcgtc tatcgccatg
      901 tcgaaccgga gctggagatc gaggatgcga gcgatctatc gcttgaagcg caggaagcct
      961 tgatcaatgc atgggtcgat caggagcatg tgattggctt tcgtggggag aatccgcagt
     1021 ggatccgcta ctacgtctgc gtgttggggg agcgtggatt tgcgctggga ttgagttttc
     1081 atcatgcact gatggatggc tggagcgagg ccagtctggt cactgagctg ttaggcctcc
     1141 atcacggtgc atctttcaca accgcggccc gtccattgag aagcgcctac cgcgattaca
     1201 tcgacgccga actgcgtgcc ctggccgacg aggaggcacg tgcgttctgg aaggatgaag
     1261 tggcgcgcag cgcgccggca gtgatcgcgc ctgatctcaa tctagtgcag gacgaggacc
     1321 ccggtgggct ggttgcggga aaaaccatcc tgcacgcgga gattgcgatc tcccaacaca
     1381 ccagcgatcg attgtttgcc ttggccgcgc ggttgcaggt tccgccacgc acagtgctgc
     1441 tggcagtaca ttccacggcg atggcgatcg ccaccggaca agacacggtg acctccggat
     1501 tgattgcgca tgggcgtctg gatcatctag acggcgatgc ggtgctgggc gtgttcctca
     1561 acgcgttgcc gttcacccag caagtggcag gtgaacgctg ggccgatgcg attcgaataa
     1621 cgtttacgca cgagcaggcg gtggagcgcc accgtcgctt cccggtggct tcgttgaccc
     1681 agtcggcggg agcgcgcctg ccgttcgatg tgttgttcaa cttcaccaag ttccatgtct
     1741 atgagcggct cgacgccgga caaccacgcc tggatctggg gcaacggggt ggcatcgccg
     1801 agaccagcct gccgttgtgc gtgaacttcc aggtcgaccc gcaaggacag tcggtccggg
     1861 gaggactgtc gttcctggcc gagcgataca gtgcccgcgc ggcgcgaggc gtggcccaca
     1921 tctatgcccg catcctcgac accctggatg cgtatggcga ggctgcgcgg ccgacgtcct
     1981 ggggtgattt ggcagggtcg gctgagcgag gcttgcctct ttccgatgcg ctggcggcca
     2041 ctgcggggca gatcgccgcg gtgcctgcgt tgcgggtcgg tagcgaaagt gtgtgccatc
     2101 gcgacctgga tgcgcggatt gccgccgtgg ccactgcgct acgccgccgc ggggttggtc
     2161 cgggtagttc ggttgagctg gatatccacg atcctgctca gcgcctcatg gccctgttgg
     2221 gcattctcaa ggccggtgcg gaggcgatac ctcaggtggc tgcgtcgccg ggcggcctgc
     2281 tgcgtatcgc attgactccc gaaacgacca gtgcaatccc taccgtgacg ctgcaggcgc
     2341 tgctcgccgt accggtggca ggcgattccg tacgcgtgga tacggacacc gaattgcaga
     2401 tcgtcgacag gcatggctgc gctgtgccgc ctggcgtgat cggcgagctg tgcctgtatg
     2461 acgcgagtat cgttatgggc gaggagcgca gggcgtatcg cagcggtctg ctggcgcgtc
     2521 tgctgcccga cggttcattg gaatggttgg gcgcgtgtgt ccaacggatc aggcatcgga
     2581 gctttggtat cgtgccggcc gagatcgagc actgtctcgt cgtgcatgcc caggtatccg
     2641 atgtggtggt ccgcaaggtg accggcccgg accacgagca cctggtggca ttcgtggtgc
     2701 cggcagcagc cggcagccca ccggactggc aggaattgcg tcgccacgct gcgcagaccc
     2761 tgccgccgca tcatgtgcca gaccattacc tcgccctgga ttgcctgcct ttcgatgcca
     2821 ccgggcaact cgatgatgtg gcgttgcgcc tggttgccgg tggtcaagct gcatgcgagg
     2881 acgaggcccc cgtcggcgac ctggaaacgg tgctggcctc gctgtggtcg gacgtccttg
     2941 gtatcgccgc catcggccgg cacaccgact tcttccagat cagtggcgat tcgattcagg
     3001 caatgcagat taccgcacga gtggaaaaga ccttggcggt gctcgcacca gtaggcctga
     3061 tgtatgccaa tcccaccatc gccgagtttg cggcggcgtt gcgcgatgat cccaatagcg
     3121 gacgtcgtgt gatgcgcgcg gccgagctgc tggtgcggtt ggccactgag cggcacgcac
     3181 tgccgccggc aggtgaccct gtgcgcgacg aggcgaggtt gatggaggcg aaggaatgat
     3241 ccgcattacc agccaggacc aagaggccgt tgcgcgcctg ctggccgaag aaggactgtt
     3301 ggagtcggca ccgcccgttg tacgggtgac cgatgcgcat cgcgcgccgc tctctgacta
     3361 tcagtacagt ctgtggctgg ccctcaacgg tggcggtgct cgccatgcca acgtgccgct
     3421 ggtgctgaag atatccggag gaacgctgga gggcgctgtg ctggagcagg cgttggtatc
     3481 catcgccgag cagcatgaag cgctgcgttg tctgatcgtc gtcgaggacg aggttgcctg
     3541 gcaggtgccg caaccgctgc atcgcctgcg cctgcggatg gagcgggtag atgctggatc
     3601 gctagacgcg cgtatcgatg cgctcgtcaa tgcacctttg gatatccgca cagagctgcc
     3661 gtaccggctg cacctgctgc aggtagacgc cgcgttgagc tatcttgtcg tggttaccca
     3721 ccacttggtg tttgacggct ggtcgctcgt gctgttgcag gatgagttgc agatgcgcta
     3781 tgcgcagttg ctgcgcggtg ccgcactgcc gccgccttcg ttgaagccgc ggcacctgga
     3841 ctttgcattg tggcaggcca gcgatgccgg ccaggcaagc cgtcagaaag ggctggagca
     3901 ttggcggcgt cttctccagg gcgcgcgttc gcgcctgcat tggatggggg tgtcgcgtgg
     3961 gcaaggcacc ttcgcgcaag ccggaggcaa cttcctttcc gagctgcctc agcccctgtc
     4021 ggccaaggtg catgccttcg ccgccgcgca ccgtaccacc gtcttcgtcg tgatggtctc
     4081 ggtttacgtc gaagtgctgt cgcgcttctg cctgcaggac gacctatgcg tgggtacgcc
     4141 gacctcggcg cgcgatcagc tcgatctgga aaagatgatc ggttacttcg ttaacacgtt
     4201 gctgcttcgc caccagcgcg agccctggca gagcttcatc gacttactac gcaggatgga
     4261 cgcgcagttc cggttggccc gcgaacacca ggccgttccg tttcatgccg tcacccgagc
     4321 gcttgaaggc gtgcgcggca gccagcagcc tttcactcag gcgatgtttg cctaccagac
     4381 cgagagcagc ggtactgggc tcggttttca atccggtggt ctggccttcg agccttaccc
     4441 ctgcgagtta aatgaagcgc gctacgactt gctgctgacc gtgctgtcca agcatcgaca
     4501 gctggcgatc aatatcgagt accgcgccca tctgttcggc atccgcacca ttgcacagtt
     4561 cgccgatgcg tacttacggc ttctggacgc tgcgatcacc aatccttctg cacgccttgc
     4621 tgagctcggt gtcgaggcgc cgttcgcgct acaagcggtg gcgccgacga tggcgtcgct
     4681 ggcacgcccg gcgagtgcgg aaggacgcca gcgcctggca tcgctcgtac ggattctggc
     4741 ggcggttggt atcggatgcc gctcgcgggt cggcctagcg ggccaaccct gcgaagccca
     4801 agcccaggtg ctactggcgc tgctggaccg aggtgcctgc tgcgtggtgc tggacgcgca
     4861 gaccgtggtg gatggtggcc cgggctatgc cgaacagatg ggtgtgcaga tcattgtcac
     4921 agacggtacc tggcaggccg cgctgcaggg cgtggtggcc acggtactcg acgtggagca
     4981 cctggttgat gccggcggcg acgcgccggt atcgaaattc gccctgtcgc aactggtccg
     5041 ggtcgaggcg ggtcccgaag gggcggcgcc ggggcagatc gtgtttccag ccgaggcgat
     5101 cattgccgga ttatcagcga ccggctgcct gaccaatcta gccgggtggg gctcggaccc
     5161 ccatgcgccg gtcttcgatc gggtaatggt gcagttggcg cagtgtatga gtgccgatat
     5221 cggcacaccg caggttcggg tagacggcat tccactgcgt agcgacgaag gcgccggcca
     5281 ggtgctgcat cggctgggat tcggagatct ggacgcgccg cgccgcctgc atgccgaggg
     5341 cagtgtggat taccggtatt tgctgcgtgt gcctgagcgc atcgtcgatg gcagtatctg
     5401 ccatgttcgt agcggggcgt ccagccgatt cgacattgct tctgccgtgc tgctggaccg
     5461 ccatgccggt ccggtcgacg cgggcatgcc gggcgaactg ctgctgggag gggcggcgct
     5521 ggcctggggc tacgcgggcg acgcgcgccg tacggccgag catttcattc ccgatccggc
     5581 cgccccgcac cccggtgccc gactgctgcg cacaggtgcc tgggcgagcc acgatcccga
     5641 cggcggcctg cgtctgctgg gacatgagca gttgcgtgtg gaccatcagg gagtggtgtt
     5701 cgatctggcc gaggtcgagt gcgagctgct tgcgcttgac ggcgtcgtgg ctgcgcgtgc
     5761 acagcgggac gatgagtccg gacgtggcgc catctccgtc tcactggtcc tggatggagg
     5821 tcacacctat agcgctgttg ccttgcgtga gcatctcgcg ccgcgtttac ccggcaaggc
     5881 gctgccctca cggttcctgg taaccgccgc cccgatacgg ggagtggaca tgggcatcga
     5941 gccggccgcg tttcaggtac tgctggcgca ggacggtacc gatcctgcgc tggaacgcat
     6001 cgaggcgatc ctgcttgagg tgtggcaaca gacactggac tgcgtcgttc accgcgacga
     6061 caacttcttc gaacttggtg gcgattccat gctttgtctg gtggtgcagt cgcgcgcggc
     6121 aaagcgcgag gtgcagttcg ccgtggaaga cctgttcgcg caccagaccc tggccgcgct
     6181 ggcagcgcat tgccatcacg gtgtggtgcg caatcaggat gttggacctt tcgatctggt
     6241 cgctcccgaa gatcgcgtgc acctgccggc cgacgccgaa gccgcttatc cgatgagccg
     6301 gctgcaagct gggatgtttt accactcgcg cgacgcctcg cagcgcctgt atttcgatgt
     6361 cgtgcacgtc tggctggaag gcaatgccaa cgtccccctg ctgcgcgact gcctgcaggg
     6421 tgtcttggcg caggccgaca cctgccggtc caccttccac atcaccggat acagcgagcc
     6481 gttgcagatt gtccgccgcg accgatcggt tccgatcgag ttgatcgacg ccgcagccag
     6541 cgaagatgcg cagatgcagt cctgcatcga ggcgtggacg caggacgacc tggcccgcgg
     6601 tttcgacatg gagcgccatg cgccgatccg ctgtgcgatc catcgtttct ccgatacccg
     6661 atcggtgatg tcctacagct tccaccatgc attgctggat ggctggagcg aagcccagat
     6721 cacggtcgat acgttgtctc tgtatgcgca gtgccgtgcc gggcaggagc gtcccgtagc
     6781 ggcgccacgc ctgcgatacc gcgagttcat cgcgctggag cgggccgccg aaaccagtac
     6841 ggcgcagcgc agcttctggc aggcctatct gcaggacgtg cactgccgcg acatcccggt
     6901 tatacaaggg gcagaaacgg aggacttggc aggcgcgctt gagctgccgc tttgtgccac
     6961 ccggtccgcc cagctgcaag cgctcgccgc atcactcaag gtatcaatca aggcagtgct
     7021 gttggcggtg cactgccatg tgatggccat ggtgaccggt tcgcccgatg tgatcaccgg
     7081 tgtaccgttc aacggccggc cggaacttgc aggaggggcc caggcgctcg gtttgttcct
     7141 gaataccttg ccgctgcggg tgcgcacaga tcgctgccac cattggcggt cgttggtcgc
     7201 agccagtgcg cgtagcgagg cagagatggc gccgtaccgc cgcttcccgc tcagcgccgt
     7261 gatcgccgcg actggggagg tcgcgcgtcc gaaagtgctg ttcaactact tgcacttcca
     7321 caactacgac acactggacg aaacgcttcc cttgcagatg acggcgcgta ctggcgtggc
     7381 ggtcaacagc ttaagttacg tggtcaactt ctggacagat ccaggcgaga agcgcatctt
     7441 cggcatgcta agcgtgccgg cgcaggaacg ggagcacggc cggcagatcg ccgcgctgtt
     7501 cgagcactgc atcgcgtcca tcgccgacag tcctaacagc gttctgccgg agccgccgct
     7561 cggctacgcc gcctaccgcg atactgcacg cactgctggt atttccaacg gcgacggggg
     7621 cagtggcggt gaatcggccg caattgtcga tcgcggcggc gcgccgcaat cgccaaccga
     7681 acatgtggtt gcatcggtct ggaggaaggt gctgggcatt gacgatgtgc agcgcaacga
     7741 cgagttcaac gccctcggtg gcgattccat cgccgccatg cgagtggtgg cggaactgga
     7801 gcgcatttac gagtgcgaca tcgacatggc cacgatcctg ctttttccta gattggcgac
     7861 gttctgcgcg gcgctggacc gcgacgcgac atacggtgag gacatcatca ctagctcgcg
     7921 gttgctgatg gaggcctacc gtgcgcgcct gcgccgcgat gctgcgcccc gcagcggggc
     7981 cggggcatga agatcagcgc ggaaagcatc gccacgttgc acagttcacc cgcgcggcta
     8041 gccgctgcaa caacgtatcc ggccgatgtg atggtacgtc tgtggggcgg cgaccaagga
     8101 gtcccgctgt ttctggtaca cccagtaggt ggaggggtgg gctgctatct accgctggtg
     8161 caggcgctta agccgacgta tccagtgtat gcccttcgcc accctggctt gaacggcgaa
     8221 tcaccgcgac aggcgctgga cgatctggcg cagcgctacc tggacgccat cctcagtgtc
     8281 cagcgtggtc ggccttaccg gctggggggc tggtcactcg ggggagtgat agccgcgttg
     8341 atggcggccc gcgcggaagc gctggaggag ccgccttcgc tgctgctggt gatagatagc
     8401 cctgcgtgcg ctgcggacgg cagctttgtt catgtcgaaa gctcctcagg ccccgatgag
     8461 gacgaagacc aacgggcgct tttgcaggag atggaacgca atgccgctgc gctgcacggc
     8521 gaccacgacg cactggctgt cctacgcgct gtgcttgccg ccaatgcaga agcactgtcg
     8581 gtctatcgga tgacggcgac ggtgcgcgct gtgcattaca tcggcgccgg gtctgacctg
     8641 tcagatcgcg gctggcgggc gctcgccagc gagcgattcg aacggcgtca gtgtacgggc
     8701 aaccactatt cgatgatgga cgcgccgcac gtgtcgatgc tggcccggca ctgcgccgaa
     8761 tggctcgcac cgcgcacgat cgttactaca ggagatgcct gagccgcatg gatatcaccg
     8821 acctcgacct caagctgctc aacgctcacc gtcgcagccg ccgcagtgag gagcgtgcag
     8881 ggattgtgct ccaacccggc gatcagggtc cgttgtcgtt cgcgcagtcg cgaatggcct
     8941 acctgcagct gtgcgatccg gcatccagcc agtacaacat gccttttgcc ttccgggtcg
     9001 atgggacgct cgaccgcgca gcgttgctac aggcaattgc gtggctgctg gaccgccatt
     9061 ctgtgctgcg cagcggtgta cacctggtcg acggcgagcc ggtacagcgg atccatccga
     9121 ccggcgaggt acgaatcgac gaatgcaacc tgagcgatct gccgtcgcag gtcgctgagg
     9181 atgcactgcg cacgtggatg ggcgagcgcg tccgggttcc gtttgcgctg gacgcgggct
     9241 gcatgctgcg cacagagctg gcccttttac ccggcgaaca aacgttggtg ctgctcacga
     9301 tgcaccacat cgccagcgat ggttggtcgc tgggcatcct caaggccgaa ctgtcggctg
     9361 cctacgcggc gttcgcacaa ggcacggtac cggtcctgcc ggcgttgccg atccgctacc
     9421 tggactttgc cgcgtgggag cagcgcaatg ctgaacgcga tgccgaacgg catttcgcgt
     9481 actggcagag acagctggcg gaagtggata ccttggctac gctggtccac gaccgaccac
     9541 ggggggcggg gatagggtcg cccggcagta cggtggcact ggcattgggt tgccgtagtt
     9601 cggcctcgct gcgtgagctt gcgcggcagg aaggtgccac gggctacgca gtggcagcgt
     9661 ctgcctttgc ggtggtcctc tcgcggatgg gcaacgcagc cgtagtgcaa ttcggtacgc
     9721 ctaccgccaa tcgcattcgt gccgaaaccc aaggattgat cggcttcttc gtcaacatgt
     9781 tggtgatccg gctgcaggtg cgcggcgacg ccagtttccg ttcgctcgtg cgcgctgccc
     9841 ggcagaccgt ggccgaagcg cagtcgcatc agagcgtgcc gtacgagcag ttggtggaac
     9901 ggctgcaggg cacgtcgcgt ccgcagcgaa atggcttgtt ccaggtcgtt ttttcctatg
     9961 atgcgatggc tgcggtgacc gcgccgatgc ggtttggtcc gcatgttgca gttgccgatg
    10021 tcgcgccgca ccagaccgcc aagttcgacc tcacggtgaa catggtcgag agcggtgatg
    10081 aactgttgct cgtggccgag tacgcatcgg acgtattcga gcgcgcacgc atcgaagcga
    10141 tctgcgcgca gtaccgcgac acgctggagg cagtgctgtc cgcgccggac gttgcgctgg
    10201 ctgcattgtt cgcgccggcg caactgcagg aggcactgcc ggtggctcgc cactgcagcg
    10261 ccgacctgtt tgcgcgtctg caggcgcatc cgccacaggc tatcgccctg cagggcgaga
    10321 ccgtgctgga ctacgccacg ctgttggcga aggtggagcg gctggctgta cgcctgcggc
    10381 tgcgcggcca ggggccgggc tcggtggtgg gcttgctgat cgaagagcgg gccacgctga
    10441 tcgtggcgat gttggcctgc ctgcgcgccg gcgtggcgtt cctgatgctg gacgcgggct
    10501 atccggctac gcggctgcgc tacatgctcg atagcggccg tagccgcttc ttgctacggc
    10561 agggggcggt accgccgctg accgcgttgc aggtgctgga tctggacgcg ccggatagcg
    10621 atgccgtggg caccccgggg ccagtgaccg acggggcggt gtcttcgata ttgcacacct
    10681 ccggctccac cggcgagccc aaggcggtgg cgctgccggt cagcgggttg atccagcacg
    10741 cgctgcgtat gcagcagctg tggcagctgg gcccggacga ccgcgtgctg cagttcaatt
    10801 cgccggcgtt cgacgcgttc ctggaagaag tattcacgac gct
//
