LOCUS       NZ_JABBXA010000018     21026 bp    DNA     linear   CON 07-NOV-2024
DEFINITION  Microbispora sp. H13382 NODE_18, whole genome shotgun sequence.
ACCESSION   NZ_JABBXA010000018
VERSION     NZ_JABBXA010000018.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora sp. H13382
  ORGANISM  Microbispora sp. H13382
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 191265)
  AUTHORS   Liu,C.
  TITLE     Selective isolation, identification and anti-microbial activity
            study of Microbispora
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 191265)
  AUTHORS   Liu,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-APR-2020) Microbiological Resources Collection Center,
            Sichuan Industrial Institute of Antibiotics, 168 Huaguan Road,
            Chengdu, Sichuan 610052, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014161445.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 07:22:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,982
            CDSs (total)                      :: 7,906
            Genes (coding)                    :: 7,786
            CDSs (with protein)               :: 7,786
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 21 of 121
            Pseudo Genes (incomplete)         :: 104 of 121
            Pseudo Genes (internal stop)      :: 8 of 121
            Pseudo Genes (multiple problems)  :: 11 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:45:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 70594
            Orig. end                         :: 91620
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABBXA010000018.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21026
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21026
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21026
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11026](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11026
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(194..210)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.62"
                     /tool="antismash"
     misc_feature    complement(195..210)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.77"
                     /tool="antismash"
     regulatory      complement(241..364)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            complement(462..1925)
                     /locus_tag="HHX41_RS29330"
     CDS             complement(462..1925)
                     /EC_number="2.7.11.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019334.5"
                     /locus_tag="HHX41_RS29330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_182908534.1"
                     /sec_met_domain="Pkinase (E-value: 2.5e-35, bitscore:
                     115.7, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAVGPLLTGDPAEIGGYRLEGRLGAGGQGVVYLGRAAGGAPVAV
                     KLLHEGWSGDEDARRRFAREIAAAGRVAPFCVARVLDFDLDGPRPYVVSEYVEGPTLQR
                     AGRRSGPALHRLAVATATALAAVHQAGIVHRDFKPANVLLGSDGPRVVDFGVARGLGAT
                     TATGGTVGTPAYMAPEQIAGEPPAPAWDVFAWGGVMVFAATGRPPFGDDALPAVLNRVL
                     TKEPDLGDLEEPLRSIVALALRKNPAERPGILDITMRLLAAVPEGTAGSLPAVLTAGRH
                     SVAPEPGTVPSRRGSGRRRGLLAGAAVTLAAATTGGVLLSVLPSEGAAENVAGGDARGT
                     AVAAAVSTPAASPSPSFSPSPTPASAPTPTARVPLRFTARFAGVWRGRVDYEPGAYDTL
                     VLTVPKGGDTVTERFVDYHCVGTSRLQVVSGTTVRLKRVSMRGNCVRNGTIYLTVHDNG
                     TMTFDYNGHGENKWTRDEPFHMIATLKRT"
     misc_feature    1985..1998
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 12.19"
                     /tool="antismash"
     misc_feature    complement(1985..2000)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.19"
                     /tool="antismash"
     gene            2029..4686
                     /locus_tag="HHX41_RS29335"
     CDS             2029..4686
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014717.5"
                     /locus_tag="HHX41_RS29335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_182908535.1"
                     /transl_table=11
                     /translation="MVRMVRARLPLVVRRAPAEPLLLAAAFGSILLATTAISALLLHAG
                     SATQAGLRRALETAPLASTATVVTSSVTAGDFARIDRAVRAGIAHAHEEVPVRVTVRVE
                     SASYALKGQDRGDQPVLTRFAAYEGLDGQADLVSGRWPTEKTAAALSEPAARAMGVSAG
                     DEFTVVGRLDGKPVRVHVTGVFRLRDPDDPRWKGEDLLRYGTRTGDFTSRGPLVVPEGA
                     FLGRFGTGVSARWLAEPDLRRLSPDRLRPFAASVAGTSAAVRSGCPRCTLTETLSGMLL
                     RLDRGALVARSTMLVPVLQLLVLSAYALALTARLLAEHRRMETALLRSRGGGSPRLAAM
                     AAGEALLIALPCAPAAPFLAPVLLRLVNAFPWIEATGVAPPRAPDGATFAVAAVVALAC
                     AAMLAAPPLLAARRTYVEEQAARGRADRPGLLQRAGADVALLVLAALAVWRLRGQDAPE
                     TARLGGELGLDPLVGAGPALALLCGGMAALRLVPAVARVAERATRRRPGFGPATAARQV
                     SRRPARYSGPALLLTMATAIGVLSLTTAATWRGAQEDRARHLAGAALRVPALPGDDART
                     FTTLPGIAAAVPAHRATVVADGADATLIAADAAQLGRVLMLRPDLSELSPATLASRIAG
                     SAGQPLLPVVVTPGLADTTRITAGTAAIPIRVVGVVTAMPGTPEGAPALLADLTALRGK
                     GAEGQVTEWWLAADGHDTARAAAALAAGRGDVVDVAALTASLRDDPTAAGLQGALLLGF
                     AAALAFAVLGFLVNAAVAARERRGEFAVLGALGVSFRQTLGLLAAEQSFVIGLSLAGGA
                     ALAVAVSAAVVPPMVTAGYATAGGLPVLLDVPWSQVAALAAAVLAVLLVIVAGLARSLH
                     RREPAAALRAGEAS"
     gene            4683..7145
                     /locus_tag="HHX41_RS29340"
     CDS             4683..7145
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014717.5"
                     /locus_tag="HHX41_RS29340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_182908536.1"
                     /transl_table=11
                     /translation="MIRLLGVHRGVVALLAALVFGAALVVSALPRMVESSLDAAARSVI
                     GSAPPATASLAVQFTRRFDLTPMRTTAEAARADAAWRELLPPALREVADPVPFFDFSAP
                     PMLLNEQTHRYLTLKWVSGADRRVRYVEGGPPGPGSGTRLEVAVPVVAATEMSIKTGDT
                     LRLGALTAKVTGLFEPARSADRFWAIEPELTYVIHHRVPLATEDDLIVTALTDGDSLAG
                     AELPMVFRWLVTPAADRVTAGNAAAVLAATEEFGRRLGRQDLELALSTGFDRILREYLD
                     RLAVTRALITVFLGGLAVVCLGTTALAVLLLVGRVHGDLLLMRARGASLAQVVLACGGA
                     VALAAVPAAAAGQVAAGFVPGAPTAVARLGPAALAAGTVAIACAAVALRQSTDRRSGKA
                     LRRMVMEILVLVVAVTSLHLLRTRGLATGDAFLALAPVLLAQAAALAVLRAGPAVIHLA
                     FRAAARRSAAVPFLGLAAARAVPGAALPVLTLLPAVALAAYGMVTAGGLEEAQRQAAWE
                     RIGAEIRVERAQGIAPETLERIRHAPGVRAVVPAAAGTTVAEVGFGGRPATVVAVDLGA
                     YRRLVAGSPLHLPAPGTGVLVSPDLSAMRSFEIGWPARMTVTPAGTVDAMPGVRAGDGA
                     LIVLPTAPEHVNTLLIAGDAGAVRPLLPSGASMTTVADALADITGTPLTAALTAALRVA
                     AAALAAYALAAVAIALTGGAARRAEDLGLLRALGLSRRQAGLITVLEAAPLLVLTAVAG
                     LAAGLAMPALLGPGIDLSAYAGGRQGALAAAALLPVLPCVLAGALAAGVAAVALTGAYL
                     GGSRGHAG"
     gene            7129..8082
                     /locus_tag="HHX41_RS29345"
     CDS             7129..8082
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541806.1"
                     /locus_tag="HHX41_RS29345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_310742240.1"
                     /transl_table=11
                     /translation="MDTLADLEARATRGGPAFGADAHILCDNLVRIYKTEGSAAVEVVA
                     LQGLDLLIGRGELVAIVGASGSGKSTLLNILSGLDVPTAGLARVAGIDLLSMTPRDRLR
                     YRRSVVGFVWQQTARNLLPYLTARENVTLPMRLAGGTSRPARSSRTDELLELTGMADRA
                     DRRPGEMSGGEQQRVAVAVALANAPEVVLADEPTGELDSESAETVFGVLRHANRELGVT
                     TVVVTHDPMVSEQVDRTIGIRDGRTSSETFRRTSSDGRVVAEEYAVLDRAGRLQLPREF
                     INALSMEHRVRLELERDHIGVWPSAAGDDTEEEMNE"
     gene            8075..8743
                     /locus_tag="HHX41_RS29350"
     CDS             8075..8743
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541186.1"
                     /locus_tag="HHX41_RS29350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_182908537.1"
                     /transl_table=11
                     /translation="MSEPLVVVEGLRKTYPKGVRALRGVSFEAHPGELVAIRGRSGAGK
                     TTLLNLVGGLDRPDEGRVRVAGQPVPELPEEGLLRLRRDVVGFVFQSFRLIPVLSAAEN
                     VGVPLRLARVPAKDREERVKVLLSLVGLSDQAEQRPYELSGGQQQRVAIARALANRPRL
                     LLADEPTGQLDSQTARQIMELLRALVRGEGVTALVATHDEGLVGLADRVLELKDGEFLS
                     "
     gene            complement(8747..9727)
                     /locus_tag="HHX41_RS29355"
     CDS             complement(8747..9727)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893885.1"
                     /locus_tag="HHX41_RS29355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldo/keto reductase"
                     /protein_id="WP_310742241.1"
                     /transl_table=11
                     /translation="MQESVQEMVLRPLGRGRLQVTPMGLGLAALGRPAYITLGRDADLG
                     GDRDVAAMRARTWEVLDAAWAAGVRYVDAARSYGLAEEFLAGWLADRGVRPGEVAVGSK
                     WGYEYVGGWRMDAGRHEEKDLSAERLRRQLGETRELLGAHLSLYQIHSATVESGVLDDE
                     EVLGELRALRAEGVAVGLSTTGPRQAATIEKAVAAGLFDTVQSTWNLLERSAGEALARA
                     HAAGLGVIVKEGVANGRLTAHAAPPALARAARERGVTPDALALAAVLARPWAGVVLSGA
                     ATTAQLAGNLTALAVTWDEEAEETLAGLTEDAETYWARRAVLPWT"
     misc_feature    complement(9807..9817)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            10001..11026
                     /locus_tag="HHX41_RS29360"
     CDS             10001..11026
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017623769.1"
                     /locus_tag="HHX41_RS29360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_310742242.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.2e-66, bitscore:
                     216.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEPVAAGVRTAGDVLARTRDLVEPALRHAVGTLPPSMRRVAGYH
                     FGWWDARERPVRASGGKALRPAFTLLAAEGAGGDADAALPAAVAVELVHNFSLVHDDVM
                     DGDTVRRHRPTVWNVFGRAEAILAGDSLLALAFTVLAGGGRPAESTRALARCVQSLLDG
                     QSADLGFEQRADVSLGECVRMAEGKTGALFGCACALGGLHGGATTEQVAALRVFGERVG
                     LAFQLVDDLLGIWGDPAVTGKPVHSDLRNRKKSLPVVAALTSGTRAGGALSVLYRRPLA
                     QTDLPRAARLVEEAGGRAWSLARVDDLLSEALEALRSAEPAPGAAAGLEALARLATDRD
                     R"
     gene            complement(11038..12087)
                     /locus_tag="HHX41_RS29365"
     CDS             complement(11038..12087)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013153725.1"
                     /locus_tag="HHX41_RS29365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glucose 1-dehydrogenase"
                     /protein_id="WP_182908538.1"
                     /sec_met_domain="ADH_N (E-value: 1.4e-15, bitscore: 50.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALTVVPHRAGSPALTEVPDPEPGPGGLLVEGVAVGVCGTDREI
                     VAGDYGWAPPDRERLVIGHESLGRVRQAPPGSGFAPGDLVVGLVRRPDPVPCGACAHGQ
                     YDMCRNGRYTERGIKELDGYASETWCVDASYAVRLAPGLGECGVLLEPASVVAKAWEQV
                     DKVGARSWFEPRTALVTGAGPIGLLAALLGVQRGLAVHVLDRVTTGPKPALVADLGAEY
                     HTGWVEDVVRSTRPDVVIEATGAADVVFGAIAATGPYGIVCLTGVSPSGRRLTLDAGTL
                     NREIVLENEVVIGTVNANHDHYAFAAGALARADSGWLARLISRRVPLHRYTEAFERRDD
                     DVKVVLTLG"
     gene            complement(12109..12585)
                     /locus_tag="HHX41_RS29370"
     CDS             complement(12109..12585)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013231.5"
                     /locus_tag="HHX41_RS29370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_182908539.1"
                     /transl_table=11
                     /translation="MSAEIAEETDPALEEDAWSVEDASLALVEMTLTAVTRGAGLSVTQ
                     LRVLLAVDRHGPLNLSGLADLLGMSVSATGRLVARLHTAGLLTRLLSPHSRREVSIDVT
                     ETGRRSLERVRAARRGHIAAALRRLPPDSRRTLARTLREFTAAASDGPGAGGHD"
     gene            complement(12582..15584)
                     /locus_tag="HHX41_RS29375"
     CDS             complement(12582..15584)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540961.1"
                     /locus_tag="HHX41_RS29375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-binding and (Fe-S)-binding domain-containing
                     protein"
                     /protein_id="WP_182908540.1"
                     /transl_table=11
                     /translation="MTSQVLVPAPVTERPRQPYVRVRDLERDLAARVDGEVRFDPGSRG
                     AYSTDGSNYRQVPLGVVVPRTVDAAAEAIAVCREHGAPVTSRGGGTSLAGQTCNAAVVI
                     DWSKYCHRLVSVDAAARTCVVEPGIVLDVLNRLLADTGLMFGPRPSTHSQCTLGGMIGN
                     NSCGSTAQAYGKTADNVSRLEILTYDGQRMWVGPTGDEEFGRIVAEGGPRGRIYRELRA
                     IVDEHAGEIHRRFPDIPRRVSGYNLDQLLPEAGFDLARALVGSEGTLVTVLRAELCLVP
                     APKAECLVLLGYHDIGVAADAVPRIARYGPLQLEGVDDKLVDFERRKHMHPDALKRLPE
                     GGGWLMVSFGADSQKEADARACDLLEELKGSEHAPHISFIDDAKTEKKLWEVRESGLGA
                     TARVPGMRETWEGFEDSAVPPDRLGDYLRDLRRLFEEFGYGDASLYGHFGQGCVHTRIP
                     FDLVTADGVAAFRAFLERAAGLVVSYGGSLSGEHGDGQARGELLTRMFGPEVMTAFERV
                     KAVFDPGDRMNPGKIVAPYKLDENLRLGPEWTPADPPVHFGYPGDEGSFQRAVMRCVGV
                     GKCREHTGGVMCPSYRATGEEEHSTRGRSRLLFEMLNGHADSAVRDGWRSAAVRDALDL
                     CLACKGCRHDCPMQVDMATYKAEFLAHHYARRIRPADHYAMGWLPVWARVAALAPGVVN
                     ALAHAPVLSALGKRLAGLETARPVPDFAPVRFRDWYRTRGPRGGGERGPVVLWPDTFTD
                     NFHPHVGRAAVEVLESAGYRVLIPPRTLCCGLTWISTGQLGVARRVLRRTVRTLAPALR
                     RGIPIVGLEPSCTAVFRADAPELFAHDRDFARLREQTRTLAELLGETDGWDPPRIDRDA
                     VAQPHCHHHSVLGFGADLALLARAGVRAEAVGGCCGLAGNFGFTAGHLEVSMTCAEHEI
                     LPAIRAAGAGTLVLADGFSCRTQIEQAGVGRRAVHLAELLAAGVRGTPLGDLPECRVAC
                     RPGPARVLGTR"
     gene            complement(15589..17355)
                     /locus_tag="HHX41_RS29380"
     CDS             complement(15589..17355)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540962.1"
                     /locus_tag="HHX41_RS29380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="WP_182908541.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2.3e-48, bitscore:
                     157.6, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-37, bitscore:
                     122.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEIASEVLIRRLADWGVDTVFGLPGDGINGIMEGLRRQSDRVRF
                     VLVHHEEAAAFMAAAHAKATGRIGVCLATSGPGGIHLLNGLYDAKLDHQPVLAITGMQE
                     TSVLGTGYQQEVHLDRVFEDVAEYNLVVDNPAQLPGVVDIAIRTAYARRGVAHLCLPND
                     VQVAPADADPYQHVAPARPPAASPVYLSPPGVPRTDDLTAAAEVLNAARRPAILAGAGA
                     LHARAEVLAVAETLGAPVIKTLPGKAVIPDDSPYAVGGIGLLGTRPGEELVEDCDTLLM
                     VGTNFPYTKHLPEPGKVRVVQIDADPARAGVRMPTEVPMIGDAKEGLAALLPLLHRNED
                     RAHLEKYQKAMAGWRENMTALENPGRTPVAPQYLIGCVDRAAADDAILTCDSGTIATWA
                     ARHWTIRGDREFYLSGNLASMAPGLPYAIAAQLAHPGRQVIAFIGDGGFAMLMAEFLTA
                     ARLGLPITVVVNNNGSLGQILWEQMVLGFPEHGVRFGPPTSDFSAWARSCGGYGRKVTD
                     PAEVDEAVRQALAHPGPALVDVDVDPNEPPMPGKVARDQAVKFAEAFLKGQPHKAAIAT
                     TLFKDKISQLGR"
     gene            17459..18547
                     /locus_tag="HHX41_RS29385"
     CDS             17459..18547
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009077218.1"
                     /locus_tag="HHX41_RS29385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="enolase C-terminal domain-like protein"
                     /protein_id="WP_182908542.1"
                     /transl_table=11
                     /translation="MIRDLHVAAYRVPTDRPEADGTLSWDATTIVVVRADAGEAAGLGW
                     TYAPAAAATVVTDLLAPLVRGGDPMDVPRLWTAMVRRVRNASRTGVAGYAISAVDVALW
                     DLKARLLGVPLARLFGLARERVPVYGSGGFTTYDDDVTTAQLARWAHEQGIPRVKIKIG
                     ESAGTAPGRDLHRVGLARRVIGDAAELYVDANGGYSAKQAVRMERRMRDHDVRWFEEPV
                     SSDDLAGLRLVRERADADVAAGEYGGDLVYFTRMCAAGAVDCLQIDATRCGGYTGWNGA
                     AAIAAGHGLEVSAHCAPNLHAPVAAATPNLRHMEWFHDHVRIEGDLFEGAADPTGGAVR
                     PPDAPGHGLTLRDDVAEPYRVA"
     misc_feature    17462..17476
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            complement(18552..19247)
                     /locus_tag="HHX41_RS29390"
     CDS             complement(18552..19247)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017578937.1"
                     /locus_tag="HHX41_RS29390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_182908543.1"
                     /transl_table=11
                     /translation="MITPEAAPIGVLIADDDPLVRAGLVMMLGGAPDIRVLAQAGDGAE
                     ALAMAGRARPHVVLMDIRMPVMDGLAATEALRARDGAPEVIVLTTFDADEHVLRALRAG
                     AAGFLLKDTPPGEIVDAIRRVAAGHPVLSPAVTRRLIARVAEDGQDRRRARAAERLALL
                     NDREREVAVAVGRGSPNAEIAARLHLSVPTVKTHVSSVLAKLGLNNRVQIALLVHDAGL
                     LDDPLDTDG"
     gene            complement(19244..20440)
                     /locus_tag="HHX41_RS29395"
     CDS             complement(19244..20440)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017587593.1"
                     /locus_tag="HHX41_RS29395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase"
                     /protein_id="WP_182908544.1"
                     /transl_table=11
                     /translation="MDPSAAPRHRRSRRDWLVDTAMFVLAVAFGFYTSVERLHATPLPP
                     AWLFSLDQLVSMLGCAALWLRRRWPVGLAVTLVALSAVFEMVAGPMLAALFSVAVHRRP
                     RTSGAVFGLSVLAAVVFTCLRPDPDMPPLALLTLGLALQGAAVGWGLFVHHRRRLVLAQ
                     RDRVARMETEARLRAEQAQHQVREAIAREIHDVLGHRLSLLSVHAGALEFNPGADPADV
                     ARAARVIRESAHQALQDLREVIGVLRAPTGEASSPTRPGPPALADLERLVAESGQAGMR
                     VELCDDLGARETVPDGTGRTAYRVAQEALTNARKHAPGAGVRLRLTGAPGEGLTVEVVN
                     DAPADAVAPDAAGGGHGLAGLAERVALAGGRLEHGSVRRDGDGGPGGWRVRAWLPWPT"
     gene            20622..20855
                     /locus_tag="HHX41_RS29400"
     CDS             20622..20855
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895159.1"
                     /locus_tag="HHX41_RS29400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_182908545.1"
                     /transl_table=11
                     /translation="MRNVTRLAGAFLVVAGISGTIDHLAVQPFWGAILNVFNRQVIPRL
                     DFLTGYEIYANLLVAVVGAVVLAAAWRRDDEA"
ORIGIN
        1 tctgcgcctt gaacggcgcg acccgtacgc cgcgccgggc gagccaccgg cacagcccgg
       61 ccaccaggac gctctttccg gcatcggagg tcgtgcccgc cacgagcagg ccgccgccgg
      121 gcgccacgtc aggaggtgga gcgcgaaacc ggcagtgagg cgcgtctgcg caggcctgtc
      181 cgggccatgg catgtccccc ctgggggtgt ccgcgccccc ggtagaaggt ccgacggccg
      241 gagtatcctg gctcccggat cggcgcttcc ctcagccttc ccgcccgtgc tgggcagtgg
      301 cgtgggtgag ggtcgctccc cggtgacagt ggcgggaccg cgccggattc acaccggctt
      361 cctccgcgtc cgtcgcttgc ggtggtcaac atacaccttt gtgtcggatg tcccgcaagt
      421 gtggtctgtc tgatctagcg gggacgctag gtgcgcttcg gtcacgtgcg cttcaaggtg
      481 gcgatcatgt ggaacggctc gtccctcgtc cacttgttct cgccgtgccc gttgtagtcg
      541 aacgtcatcg tcccgttgtc gtggacggtg aggtagatcg tgccgttgcg cacgcagttg
      601 ccccgcattg agacccgctt cagccgcacc gtcgtcccgc tgaccacctg gagcctggag
      661 gtgcccacgc agtggtagtc gacgaaccgc tcggtgaccg tgtcgccgcc cttcggcacg
      721 gtcagcacga gcgtgtcgta cgcgccgggc tcgtagtcca ccctgccgcg ccacacgccc
      781 gcgaagcgcg cggtgaagcg cagcggcacg cgcgcagtgg gagtcggagc ggacgccggc
      841 gtgggcgagg ggctgaatga ggggctggga ctcgccgccg gagtggacac ggcggcggcg
      901 accgccgtgc cgcgcgcgtc gcccccggcg acgttttcgg cggcgccttc ggacggcagc
      961 accgacagca gcacgccccc ggtcgtcgcg gccgcgaggg tgaccgccgc ccccgcgagc
     1021 agcccgcggc ggcggccgga gccccgccgt gaggggacgg tgccgggttc cggagccacg
     1081 gaatgccgtc cggcggtgag cacggcgggg aggctcccgg cggtcccctc cggaaccgcg
     1141 gcgagcagcc gcatcgtgat gtcgaggatg cccgggcgct cggcggggtt cttgcgcagg
     1201 gccagcgcga cgatggagcg caacggctct tccaggtcgc cgaggtcggg ctccttggtg
     1261 agcacgcggt tcagcacggc gggcagcgcg tcgtcgccga acggcggcct gccggtggcc
     1321 gcgaacacca tcacgccgcc ccacgcgaac acgtcccagg cgggcgcggg cggctcgccg
     1381 gcgatctgct cgggcgccat gtaggcgggc gtgccgacgg tgccgccggt cgccgtggtc
     1441 gcgccgagac cgcgggcgac cccgaagtcg acgaccctcg gaccgtcgga ccccagcagc
     1501 acgttggcgg gcttgaagtc gcggtggacg atcccggcct ggtgcacggc ggcgagtgcg
     1561 gtcgcggtcg ccacggccag ccggtgcagg gcgggcccgg accgccgtcc tgcccgctgc
     1621 agcgtggggc cctccacgta ctcgctcacg acgtagggcc gcgggccgtc caggtcgaag
     1681 tcgagcaccc gggccacgca gaacggcgcg acccgccccg cggcggcgat ctcccgcgcg
     1741 aagcggcggc gggcgtcctc gtcccccgac cagccctcat gcagcagctt gaccgccacc
     1801 ggcgcgcccc cggccgcacg gccgaggtag accaccccct ggccgcccgc gccgaggcgg
     1861 ccctccagcc gatagccgcc gatctcggcc ggatctcccg tgagcagcgg ccccaccgca
     1921 ggcatgcagc cctcctcggc ccgttttccc ctcaccttag atgaccgtaa cggtggtgct
     1981 tctcgatcat gcttgtcatg atgccgggat gagcgtggtc aggcccggat ggtgaggatg
     2041 gtgcgggcgc ggctgccgct ggtggtccgg cgcgcgccgg ccgagccact gctgctggcc
     2101 gccgcgttcg gctccatcct gctcgccacc accgcgatct cggctctgct gctgcatgcg
     2161 gggtcggcga cccaggcggg cctgcggcgg gccctggaga cggcgccgct cgcgtccacc
     2221 gcgaccgtcg ttacctcctc ggtgacggcc ggggacttcg cccgaatcga ccgcgccgtc
     2281 cgcgcgggga tcgcccacgc ccacgaagag gtgcccgtac gggtcaccgt acgcgtcgag
     2341 tccgcctcgt acgcgctgaa gggacaggat cgcggcgacc agcccgtcct gacccggttc
     2401 gccgcgtacg agggactgga cggccaggcg gacctggtga gcgggcgctg gcccacggag
     2461 aagacggcgg cggcgctctc ggagccggcc gcccgggcga tgggagtgtc cgccggcgac
     2521 gagttcaccg tcgtcggacg cctggacgga aagccggtcc gcgtgcacgt caccggcgtc
     2581 ttccggctcc gcgaccccga cgacccgcgc tggaaggggg aggacctgct gcgttacggc
     2641 acgcggaccg gcgacttcac ctcccgcggg cccctggtcg tgccggaggg cgccttcctc
     2701 ggccgcttcg ggaccggtgt ctcggcccgc tggctcgccg aacccgacct gcgccggctt
     2761 tcccccgacc ggctgcggcc gttcgcggcc tcggtcgccg ggacctccgc cgccgtgcgg
     2821 tccggctgcc cccggtgcac gctcaccgag acgctgtccg gcatgctgct gcggctcgac
     2881 cgcggcgccc tggtcgcccg ctcgaccatg ctggtgccgg tgctccaact gctggtgctg
     2941 agcgcgtacg cgctggcgct gaccgcgcgg ctgctcgccg agcaccgccg gatggagacg
     3001 gccctgctgc gatcgagggg cggcgggtca ccgcggctcg ccgccatggc ggcgggggag
     3061 gcgctgctga tcgcgctgcc ctgcgcgccc gcggcgccgt tcctcgcgcc cgtgctcctg
     3121 cgactggtga acgcgttccc ctggatcgag gctaccggcg tggcgccgcc ccgcgcgcct
     3181 gacggggcca ccttcgcggt cgcagcggtg gtcgcgctcg cctgcgccgc catgctggcc
     3241 gccccgccgc tgctcgccgc ccgccgcacg tacgtcgagg agcaggcggc gcgcggacgc
     3301 gccgaccggc cgggcctgct ccagcgggcc ggagccgacg tggcgctgct cgtcctggcg
     3361 gcgctcgccg tctggcgcct gcgcggacag gacgcgccgg agaccgcgcg cctcggcggc
     3421 gagctcgggc tcgacccgct ggtcggggcg ggaccggcgc tcgccctgct ctgcgggggg
     3481 atggccgccc tgcggctggt gcccgcagtc gccagggtcg ccgagcgggc gacgcggcgg
     3541 cgccccgggt tcgggccggc gacggccgcc cggcaggtga gccggcgccc ggcccgctat
     3601 tcgggtccgg cgctgctgct gacgatggcg acggcgatcg gcgtgctgtc cctgaccacc
     3661 gccgcgacct ggcgcggcgc ccaggaggac cgggccaggc atctcgccgg cgccgccctg
     3721 cgcgtcccgg ccctccccgg ggacgacgcg cgaaccttca ccacgctgcc ggggatcgcg
     3781 gcggcggtgc ccgcgcaccg cgccacggtc gtcgctgacg gcgcggacgc caccctcatc
     3841 gccgcggacg cggcgcagct gggccgtgtc ctgatgctgc gccccgacct gtcggagctg
     3901 tcgccggcca cgctggcctc ccggatcgcc gggtccgccg gacagccgct tcttccggtc
     3961 gtggtgaccc ccggattggc ggacaccacc aggatcacgg ccggcacggc ggcgatcccg
     4021 atccgggtcg tgggcgtcgt caccgcgatg cccggcacgc cggagggcgc cccggccctg
     4081 ctcgccgacc ttacggcgct tcgggggaaa ggcgccgagg ggcaggtgac ggaatggtgg
     4141 ctggccgccg acgggcacga caccgcgcga gccgccgccg cgctggccgc cggccgcggg
     4201 gacgtcgtcg acgtggccgc gctcaccgcg agtctcaggg acgaccccac ggcggccggc
     4261 ctgcagggcg cgctgctgct cggcttcgcg gcggcgctgg cgttcgccgt gctgggattc
     4321 ctggtcaacg ccgcggtcgc ggcgcgcgag cgcaggggcg agttcgccgt gctcggcgcc
     4381 ctcggcgtga gcttccggca gacgctcggc ctgctcgccg ccgagcagtc gttcgtgatc
     4441 gggctgtcgc tggccggcgg agcggcgctc gccgtggccg tgtccgccgc ggtggtgccg
     4501 ccgatggtga ccgcgggata cgcgaccgca ggcgggctgc cggtgctgct cgacgtgccg
     4561 tggtctcagg tggcggcgct ggccgccgcg gtcctcgcgg tgctgctggt gatcgtggcg
     4621 ggactcgcgc ggtcgctgca ccgccgtgag ccggccgccg cgctgcgtgc tggggaggcg
     4681 tcgtgatccg ccttctgggt gtgcacaggg gcgtggtggc gctgctggcc gcgctggtgt
     4741 tcggcgccgc cctggtcgtc tcggccctgc cccggatggt cgagtcctcc ctcgacgcgg
     4801 cggcaaggtc ggtcatcggc tccgccccgc ccgccacggc gtcgctggcg gtccagttca
     4861 cccgccgctt cgacctgacg ccgatgcgga cgacggccga ggcggccagg gcggacgccg
     4921 cctggcgcga gctgctcccc ccggcgctgc gggaggtcgc cgaccccgtc ccgttcttcg
     4981 atttctccgc cccgccgatg ctgctgaacg agcagacgca tcggtatctg acgctgaaat
     5041 gggtctccgg ggcggaccgg cgggtgcggt acgtcgaggg cggccccccg ggccccggct
     5101 cgggcacccg tctcgaggtg gccgtccccg tggtcgccgc cacggagatg tcgatcaaga
     5161 cgggcgacac cctccgcctc ggcgctttga ccgcgaaggt caccggcctg ttcgagccgg
     5221 cgcgttccgc cgaccggttc tgggccatcg agccggagct cacctacgtc atccaccacc
     5281 gcgtgccgct cgccacggag gacgacctga tcgtcaccgc gctcaccgac ggcgacagcc
     5341 tcgcgggcgc cgaactgccg atggtcttcc gttggctcgt caccccggcg gcggaccgcg
     5401 tcaccgcggg caacgcggcg gccgtgctcg ccgccacgga ggagttcggc cgccgcctgg
     5461 gcaggcagga cctcgaactc gccctgtcga ccgggttcga ccggatcctg cgggagtacc
     5521 tggaccggtt ggccgtcaca cgcgcgctga tcacggtgtt cctgggcggg ctggccgtcg
     5581 tgtgcctggg caccacggcc ctggccgtgc tgctgctcgt cgggcgggtg cacggcgatc
     5641 tgctgctgat gcgcgcccgc ggtgcgtccc tggcccaggt cgtgctcgcc tgcgggggag
     5701 cggtcgcgct cgcggcggtg ccggcggccg cggcgggcca ggtggccgcg ggcttcgtgc
     5761 cgggcgcccc gacggcggtc gcgcggctgg gaccggccgc gctggcggcg gggaccgtcg
     5821 cgatcgcctg cgccgccgtc gcgctgcgcc agtccaccga ccgacggtcc gggaaggctc
     5881 tccgcaggat ggtgatggag atcctggtgc tcgtggtcgc cgtgacgagc ctccatctcc
     5941 tgcgcacccg cggcctcgcc accggcgacg ccttcctcgc actggcgccc gtgctgctgg
     6001 cgcaggcggc cgcgctggcg gtgctgcgcg ccggcccggc cgtgatccac ctggccttcc
     6061 gggccgccgc ccggcgctcc gccgccgtgc cgttcctcgg cctcgccgcc gcccgggccg
     6121 tgccgggcgc cgcgctgccg gtgctcacgc tgctgccggc cgtcgcgctg gcggcgtacg
     6181 gcatggtcac cgccggaggg ctggaggagg cccagcggca ggcggcgtgg gagcggatcg
     6241 gcgccgagat cagggtggag cgcgcgcagg gaatcgctcc ggagacgctg gagcggatcc
     6301 gccacgcgcc gggcgtcagg gccgtcgtcc cggccgcggc cgggacgacg gtcgccgagg
     6361 tgggcttcgg cgggcggccg gccacggtcg tcgcggtcga tctcggcgcc taccgccggc
     6421 tggtcgcggg cagcccgctc cacctgcctg cgccggggac cggtgtgctc gtctcgcccg
     6481 acctgtccgc catgcggagc ttcgagatcg gctggcccgc gcggatgacg gtcaccccgg
     6541 cggggaccgt cgacgcgatg ccgggggtgc gggcggggga cggcgccctc atcgtcctcc
     6601 ccacggctcc cgagcacgtc aacacgttgc tgatcgcggg agacgccggc gcggtcaggc
     6661 cgctgctgcc gtccggcgcg agcatgacca ccgtggcgga cgcgctcgcc gacatcaccg
     6721 gcacgccgct gacggcggcg ctgaccgccg cgctgcgggt cgccgccgcg gcgctggccg
     6781 cgtacgcgct ggcggccgtc gcgatcgcgc tgaccggagg cgcggcccgg cgggcggagg
     6841 acctcggcct gctgcgcgcc ctcggcctca gccgcaggca ggccggcctg atcacggtcc
     6901 tggaggcggc cccgctgctc gtcctgaccg ccgtcgccgg gctggcggcc ggtctcgcca
     6961 tgcccgcgct gctcgggccc ggaatcgacc tgtcggcgta cgcgggcggg cgccagggcg
     7021 ccctcgcggc cgccgcgctc ctgcccgtcc tgccctgtgt cctggccggt gccctcgccg
     7081 ccggggtcgc cgccgtcgcc ctcacgggcg cctatctggg aggaagccgt ggacacgctg
     7141 gctgacctgg aggcccgggc cacgcggggt ggccccgcgt tcggcgcgga cgcccacatc
     7201 ctgtgcgaca acctcgtgcg gatctacaag accgagggat ccgccgcggt cgaggtggtc
     7261 gccctgcagg gcctcgacct gctcatcggc cggggtgagc tggtggcgat cgtcggggcc
     7321 tcgggatcgg gcaagtcgac gctgctcaac atcctgtcgg ggctcgacgt gcccacagcc
     7381 gggctggccc gggtcgccgg aatcgacctg ctgtccatga ccccgcgcga ccgcctccgc
     7441 taccggcgct cggtcgtggg cttcgtctgg cagcagaccg cccgcaacct gctgccgtac
     7501 ctcaccgccc gggagaacgt cacgctcccc atgcggctgg ccggcggcac gtcccggccg
     7561 gccaggtcgt cccgtacgga cgagctgctg gaactgacgg ggatggcgga ccgcgcggat
     7621 cggcggcccg gggagatgtc cggcggcgag cagcagcggg tggccgtcgc cgtcgccctc
     7681 gccaacgcgc ccgaggtggt gctcgccgac gagcccaccg gggagctgga cagcgagagc
     7741 gccgagacgg tcttcggcgt gctccgccac gccaaccggg agctcggcgt cacgaccgtc
     7801 gtcgtgacgc acgacccgat ggtgtcggag caggtcgacc ggaccatcgg catccgggac
     7861 ggccgcacct ccagcgagac gttccgccgc acgtcctccg acgggagggt ggtcgccgag
     7921 gagtacgcgg tgctcgaccg ggccgggcgc ctgcaactgc cgagagagtt catcaacgcc
     7981 ctgtcgatgg agcaccgggt gcgcctggag ctcgaacgcg accacatcgg ggtctggccc
     8041 tcggccgccg gcgacgacac agaggaagag atgaatgagt gagccgctgg tcgtcgtcga
     8101 gggcctgcgc aagacctatc ccaagggcgt gcgcgcgctg agaggggtct ccttcgaggc
     8161 tcacccgggc gagctggtcg cgatccgcgg tcgttccggc gcgggcaaga cgacgctgct
     8221 caacctggtc ggcggcctgg accggcccga cgaggggcgg gtgcgggtag cagggcagcc
     8281 ggtgcccgag ctgcccgagg agggcctgct gcggctgcgc cgcgacgtcg tcgggttcgt
     8341 cttccagtcg ttccggctga tcccggtgct gtcggccgcc gagaacgtgg gcgtgccgct
     8401 gcggctggcg cgggttccgg ccaaggacag ggaggagcgg gtgaaggtgc tgctgtccct
     8461 ggtcgggctg tccgatcagg ccgagcagcg gccctacgag ctgtcgggtg gccagcagca
     8521 gcgcgtggcc atcgccaggg ccctggccaa ccggccccgc ctgctgctcg ccgacgagcc
     8581 gaccggtcag ctcgattccc agaccgcccg ccagatcatg gagctgctgc gggcgctcgt
     8641 ccggggcgag ggcgtcaccg cgctggtggc cacgcacgac gagggcctcg tcggcctggc
     8701 cgaccgcgtg ctggagctca aggacggcga gttcctgagc tgaccgtcag gtccagggga
     8761 ggacggcgcg gcgggcccag taggtctcgg cgtcctccgt cagtccggcg agggtctcct
     8821 cggcctcctc gtcccaggtg acggcgagcg ccgtcaggtt cccggcgagc tgagcggtcg
     8881 tggccgcgcc gctcagcacg acccccgccc acgggcgggc gagcacggcg gcgagtgcca
     8941 gggcgtcggg ggtgacgccg cgttcgcgtg ccgcgcgcgc cagcgccggc ggcgcggcgt
     9001 gggcggtcag cctgccgttg gccacgccct ccttgacgat cacgcccagg ccggcggcgt
     9061 gcgcccgggc cagggcctcg cccgccgagc gctccagcag gttccacgtc gactggacgg
     9121 tgtcgaagag cccggccgcg accgccttct cgatggtcgc cgcctggcgg gggccggtgg
     9181 tggacaggcc gaccgcgacg ccctccgcgc gcagcgcccg cagctccccg aggacctcct
     9241 cgtcgtcgag cacaccgctc tccaccgtgg ccgaatggat ctggtagagc gacagatggg
     9301 cgccgagcag ctcccgggtc tcgccgagct gacggcgcag ccgctcggcg gacaggtcct
     9361 tctcctcgtg gcggccggcg tccatccgcc agccgccgac gtactcgtag ccccacttcg
     9421 agccgacggc gacctcgccg ggccggacgc cccgatcggc cagccagccc gcgaggaact
     9481 cctccgccag gccgtaggag cgggccgcgt cgacgtaccg cacgccggcc gcccacgcgg
     9541 cgtccagcac ctcccaggtg cgcgcccgca tcgccgccac gtcacggtcg ccgccgaggt
     9601 cggcgtcccg gccgagcgtg atgtacgcgg gccggccgag cgcggcgagc ccgagaccca
     9661 tcggggtgac ctgaaggcga ccgcggccca acggccgcag gaccatctcc tgcacgctct
     9721 cctgcacggg acacacgtta gtgactccgc cgggtgccgc ccgcagcggg tgcgcgctca
     9781 cgatggccga gcccgttcca gcgacaatca cattgcagtc tcgactgcaa tccccatttc
     9841 gggcggcgcg ccacattcgt tgtcgcggtc ctcgacgagg agggttccgg gccctgtctg
     9901 acccgatggg gcgaggggta cgtgtcgtga ggtgacggcc ggggtatgcc gacaagtcca
     9961 accggcctgt gggtccactc gagcccgagg tggtgggagc gtgacggaac cggtggcagc
    10021 gggagtgcgg accgcgggag acgtgcttgc ccggacgcgc gacctggtgg aacccgccct
    10081 gcgccatgcg gtcggcaccc tgcctccgtc gatgcgcagg gtggcggggt accacttcgg
    10141 atggtgggac gcgcgggagc ggccggtgcg ggcgagcggg ggcaaggccc tgcggcccgc
    10201 gttcacgctg ctggcggcgg agggcgccgg gggagacgcg gacgcggcgc tgccggccgc
    10261 cgtcgcggtc gagctggtgc acaacttctc cctggtccac gacgacgtga tggacggcga
    10321 cacggtccgc cgccaccgcc ccacggtgtg gaacgtcttc ggccgcgccg aggcgatcct
    10381 ggccggcgac tccctgctgg cgctggcctt caccgtgctc gccgggggcg gcaggcccgc
    10441 cgagagcacg cgggcgctgg cccgctgcgt ccagtcgctg ctggacggcc agagcgccga
    10501 cctcggcttc gagcagcgcg cggacgtgag cctgggggag tgcgtgcgca tggcggaggg
    10561 caagacgggc gccctgttcg gctgcgcgtg cgccctcgga gggctgcacg gaggcgccac
    10621 caccgagcag gtggccgccc tgcgcgtgtt cggcgagcgc gtgggcctgg cgttccagct
    10681 cgtcgacgac ctgctgggta tctggggcga cccggccgtc accggcaaac cggtccattc
    10741 cgacctgcgc aaccggaaga agtccctgcc ggtcgtcgcc gcgctgacgt cgggcacgcg
    10801 ggcgggcggc gcgctctccg tgctgtaccg ccgcccgctc gcgcagaccg accttccgcg
    10861 ggcggcgcgg ctggtggagg aggcgggtgg gcgggcgtgg agcctcgcca gggtcgacga
    10921 cctgctgtcc gaggcgctgg aggcgctgcg gtcggcggag ccggcgcccg gggcggcggc
    10981 gggtctggag gccctggccc gcctggccac cgaccgcgac cgctgactcg tccgtcctca
    11041 gccgagggtg agcaccacct tgacgtcgtc gtcccggcgc tcgaaggcct cggtgtagcg
    11101 gtgcagcggc acccgccggg agatcagccg ggcgagccag ccggagtcgg cccgggcgag
    11161 ggcgccggcc gcgaaggcgt agtggtcgtg gttggcgttc acggtgccga tgacgacctc
    11221 gttctccagc acgatctccc ggttgagcgt cccggcgtcc agggtgagcc gccgcccgct
    11281 cggagagacc ccggtcaggc agacgatgcc gtacgggccg gtcgcggcga tggcgccgaa
    11341 caccacgtcg gcggcgccgg tggcctcgat gacgacgtcc ggccgggtcg accgcaccac
    11401 gtcctccacc cagccggtgt ggtactccgc gccgaggtcc gcgacgagtg ccggcttggg
    11461 ccctgtggtg acgcggtcga gcacgtgcac ggcgaggccg cgctgcacgc cgagcagcgc
    11521 ggcgagcagg ccgatgggcc ccgcgccggt gaccagcgcc gtacgcggct cgaaccacga
    11581 gcgcgccccc accttgtcga cctgctccca cgccttggcc accaccgacg cgggttcgag
    11641 cagcacgccg cactcgccga ggccgggggc gagccggacc gcgtaggacg cgtcgacgca
    11701 ccacgtctcg ctcgcgtagc cgtcgagctc cttgatgccc cgctccgtgt agcggccgtt
    11761 gcggcacatg tcgtactgcc cgtgcgcgca tgctccgcac ggcacggggt cgggccggcg
    11821 cacgaggccc accacgaggt ctcccggcgc gaagccggag ccgggcgggg cctgccgtac
    11881 gcggccgagg gactcgtgcc cgatgaccag ccgttcccgg tccggcggag cccagccgta
    11941 gtcgccggcc acgatctccc ggtccgttcc gcagacgccg acggccacgc cctccacgag
    12001 aaggccgccc ggcccgggct cgggatcggg cacctcggtc agcgccggcg aaccggcgcg
    12061 gtgcgggacg acggtgaggg cacgcatgcg ggactcctct cccggtggtc agtcgtggcc
    12121 gcctgcgccg gggccgtccg acgccgccgc ggtgaactcg cgcagtgtcc gggcgagcgt
    12181 acggcggctg tccggtggca gacggcgcag cgcggccgcg atgtgcccgc ggcgcgcggc
    12241 gcggacgcgt tcgagcgagc gtctgccggt ctccgtgacg tcgatgctga cctcgcggcg
    12301 gctgtgcggg gacagcaggc gcgtcagcag cccggcggtg tgcagacggg ccacgaggcg
    12361 gccggtggca gagaccgaca tgcccagcag gtcggcgagc ccgctcaggt tcagcgggcc
    12421 gtgccggtcg accgcgagca gcacccgcaa ctgggtgacc gacaggccgg cgccgcgcgt
    12481 caccgcggtg agggtcatct ccaccagggc gagggaggcg tcctcgaccg accacgcgtc
    12541 ctcctcgagc gcggggtcgg tctcctccgc gatttcggcg ctcatcgcgt ccccaggacc
    12601 cgcgccgggc cgggcctgca cgcgacgcgg cactcgggaa ggtcgccgag cggggtgccg
    12661 cgcaccccgg ccgccagcaa ctccgcgagg tggaccgccc ggcgtcccac tcccgcctgc
    12721 tcgatctgcg tacggcagct gaacccgtcg gcgaggacga gcgtcccggc cccggcggcc
    12781 cggatcgccg gcaggatctc gtgctcggcg caggtcatcg acacctccag gtgaccggcg
    12841 gtgaagccga agttcccggc gaggccgcag cagccgccaa ccgcctcggc ccgcaccccg
    12901 gcgcgggcca gcagggccag gtcggcgccg aagccgagca ccgagtggtg atggcagtgc
    12961 ggctgggcga cggcgtcccg gtcgatccgg ggcgggtccc agccgtcggt ctcgccgagc
    13021 agttcggcga gggttctggt ctgctcgcgc agccgggcga agtcccggtc gtgcgcgaac
    13081 agctcgggcg cgtcggcgcg gaacaccgcc gtgcagctcg gctccagccc gacgatcggg
    13141 atgccgcggc gcagcgccgg ggcgagggtc cgcacggtgc gccgcagcac ccgccgcgcc
    13201 acgccgagct ggcccgtcga gatccaggtc agcccgcagc acagcgtgcg cggcgggatc
    13261 agcacgcgat agcccgccga ctccagcacc tccacggcgg cgcggccgac gtggggatgg
    13321 aagttgtcgg tgaaggtgtc cggccacagc accacgggcc cgcgctcccc tccaccccgg
    13381 ggcccgcgcg tccggtacca gtcgcggaag cggaccggcg cgaagtccgg caccggccgg
    13441 gccgtttcga ggcccgccag gcgcttgccc agcgcggaca gcacgggcgc gtgcgccagc
    13501 gcgttgacca cgccgggagc gagcgcggcg acgcgggccc acaccggcag ccaccccatc
    13561 gcgtagtggt ccgccggccg gatccgccgg gcgtagtgat gggcgaggaa ctcggccttg
    13621 tacgtcgcca tgtcgacctg catgggacag tcgtgcctgc agcccttgca ggccaggcac
    13681 aggtcgaggg cgtcgcgcac ggcggcggaa cgccagccgt cccgcaccgc ggagtcggcg
    13741 tggccgttca gcatctcgaa cagcagccgg gagcgtccgc gggtggagtg ctcctcctcg
    13801 ccggtggccc ggtaggacgg gcacatcacc ccgccggtgt gctcgcggca cttgccgacc
    13861 cccacgcacc gcatgacggc ccgctggaag ctgccctcgt cgccgggata gccgaagtgg
    13921 acgggcgggt cggcgggtgt ccactcgggg ccgagccgca ggttctcgtc cagcttgtac
    13981 ggcgcgacga tcttgcccgg gttcatccgg tcgccggggt cgaagacggc cttgacccgc
    14041 tcgaaggcgg tcatgacctc gggcccgaac atcctggtga ggagttcgcc cctggcctgc
    14101 ccgtcgccgt gctcgcccga cagcgagccg ccgtaggaga cgacgaggcc ggcggcccgt
    14161 tccaggaagg cccggaaggc cgccaccccg tcggcggtca ccaggtcgaa cgggatgcgg
    14221 gtgtgcacgc agccctgccc gaagtgcccg tacagggagg cgtcgccgta gccgaactcc
    14281 tcgaacaggc ggcgcaggtc gcgcaggtag tccccgagcc ggtcgggcgg gacggcggag
    14341 tcctcgaagc cctcccacgt ctcgcgcatc ccgggaacgc gcgcggtggc gccgagcccg
    14401 gactcgcgga cctcccacag cttcttctcg gtcttcgcgt cgtcgatgaa ggagatgtgc
    14461 ggcgcgtgct cgctgccctt cagctcctcg agaaggtcac atgccctggc gtccgcctcc
    14521 ttctgcgagt cggcgccgaa ggagaccatg agccagccgc cgccctccgg cagccgcttg
    14581 agcgcgtcgg ggtgcatgtg cttgcgccgc tcgaagtcca cgagcttgtc gtccacccct
    14641 tcgagctgga gcgggccgta gcgggcgatg cgcggcacgg cgtcggcggc cacgccgatg
    14701 tcgtggtagc ccagcaggac gaggcactcc gccttcggcg cgggcaccag gcacagctcg
    14761 gcccgcagca cggtgaccag cgtgccctcc gacccgacca gcgcccgggc caggtcgaac
    14821 ccggcctcgg gcaggagctg gtcgaggttg tagcccgaca cccgccgggg gatgtcgggg
    14881 aagcgccggt ggatctcgcc ggcgtgctcg tccacgatgg cccgcagctc gcggtagatg
    14941 cgcccccgcg gcccgccctc ggcgacgatc cggccgaact cctcgtcgcc ggtcggcccc
    15001 acccacatgc gctgcccgtc gtaggtgagg atctccagcc gtgagacgtt gtcggcggtc
    15061 ttgccgtacg cctgggcggt cgagccgcag gagttgttgc cgatcatgcc gccgagcgtg
    15121 cactgggagt gcgtggacgg gcgcggcccg aacatcaggc cggtgtcggc cagcagccgg
    15181 ttcagcacgt cgagcacgat gccgggctcg accacgcagg tgcgcgccgc ggcgtccacc
    15241 gacaccagcc ggtggcagta cttggaccag tcgatcacca cggcggcgtt gcaggtctga
    15301 ccggccaggc tcgtcccgcc gccccgtgag gtgacgggcg cgccgtgctc ccggcagacc
    15361 gcgatcgcct cggccgccgc gtccaccgtg cgcggcacca ccacgcccag cggcacctgg
    15421 cggtagttcg acccgtcggt ggagtaggcg ccccggctgc cggggtcgaa cctgacctcg
    15481 ccgtccaccc gggcggcgag gtcccgctcc aggtcgcgca cccgcacgta cggctgtcgc
    15541 ggccgctccg tcacgggtgc gggtacgaga acctggctgg tcatggcgtc accgccccag
    15601 ttgagagatc ttgtccttga acagcgtcgt cgcgatggcc gccttgtgcg gctgcccctt
    15661 gaggaacgcc tcggcgaact tgaccgcctg gtcgcgggcg accttgcccg gcatgggcgg
    15721 ctcgttcggg tcgacgtcga cgtcgacgag cgccggcccg ggatgggcga gggcctgccg
    15781 tacggcctcg tccacctcgg cggggtcggt gaccttgcgg ccgtacccgc cgcaggagcg
    15841 ggcccaggcg gagaagtcgg aggtgggcgg gccgaacctg accccgtgct cggggaaccc
    15901 cagcaccatc tgctcccaca ggatctggcc cagcgagccg ttgttgttca ccaccaccgt
    15961 gatcggcagg ccgagacgcg ccgcggtgag gaactcggcc atcagcatcg cgaagccgcc
    16021 gtcgccgatg aaggcgatca cctgccgtcc ggggtgggcg agctgcgccg cgatcgcgta
    16081 cggcaggccg ggggccatgc tggcgaggtt gcccgacagg tagaactcac ggtcgccgcg
    16141 gatcgtccag tgccgggccg cccaggtcgc gatcgtgccg gagtcgcagg tgaggatggc
    16201 gtcgtcggcg gcggcccggt caacgcagcc gatcaggtac tgcggggcga cgggggtgcg
    16261 cccggggttc tccagggcgg tcatgttctc ccgccacccg gccatggcct tctggtactt
    16321 ctccaggtgc gcccggtcct cgttccggtg cagcagcggc agcagcgcgg cgagcccctc
    16381 cttggcgtcc ccgatcatcg gcacctcggt cggcatgcgc acgcccgcgc gggcggggtc
    16441 ggcgtcgatc tgcacgacgc ggaccttgcc gggctcgggc aggtgcttgg tgtaggggaa
    16501 gttggtgccg accatcagca gcgtgtcgca gtcctcgacc agctcctcgc cgggcctcgt
    16561 gccgagcagg ccgatcccgc ccacggcgta cggcgagtcg tcggggatga ccgccttgcc
    16621 gggcagcgtc ttgatcacgg gggcgcccag cgtctcggcg acggccagca cctccgcgcg
    16681 ggcgtgcagg gcgccggccc cggccaggat cgcgggccgc cgggccgcgt tcagcacctc
    16741 ggcggcggcg gtcaggtcgt cggtgcgcgg cacgccgggc ggggacaggt agacggggga
    16801 ggccgcgggc ggccgggcgg gggcgacgtg ctggtagggg tcggcgtcgg ccggggccac
    16861 ctgcacgtcg ttgggcaggc acaggtgggc gaccccgcgc cgggcgtatg ccgtgcggat
    16921 ggcgatgtcc accaccccgg gcagctgcgc ggggttgtcc accaccaggt tgtactcggc
    16981 cacgtcctcg aacacccggt cgaggtggac ctcctgctgg tagccggtgc ccagcacgct
    17041 ggtctcctgc atgccggtga tggccagcac cggctggtgg tcgagcttgg cgtcgtacag
    17101 gccgttgagc aggtggatgc cgccggggcc cgaggtggcc aggcacacgc cgatgcggcc
    17161 ggtggccttc gcgtgcgcgg cggccatgaa cgcggccgcc tcctcgtggt gcaccagcac
    17221 gaaccggaca cggtcggatt ggcggcgcag cccctccatg atgccgttga tgccgtcccc
    17281 ggggagcccg aagacggtgt cgacacccca gtcggcgagc cgtctgatga gtacttcgga
    17341 ggcgatttcc gtcatatagg ccgcgctgcc cggggaatgg gaagccgaac actcaccaca
    17401 tggaaaatct ttcctctgtg ccagagtcgg agggtcatgc ccgggtaggg gcacgcctgt
    17461 gatcagagac ctccatgtgg cggcgtaccg cgtgccgacc gaccgcccgg aggccgacgg
    17521 cacgctgagc tgggacgcga ccacgatcgt ggtggtccgc gccgacgcgg gcgaggcggc
    17581 ggggctcggc tggacctacg cgccggccgc cgccgcgacg gtcgtcacgg acctgctcgc
    17641 gcccctggtg cgcggcggcg acccgatgga cgtgccgcgc ctgtggaccg cgatggtccg
    17701 ccgggtgcgc aacgcgagcc gcaccggcgt cgccgggtac gcgatctccg cggtcgacgt
    17761 cgcgctctgg gacctcaagg cccggctgct cggcgtgccg ctcgcccgcc tgttcggcct
    17821 ggccagggag cgcgtgcccg tgtacggctc gggcgggttc accacgtacg acgacgacgt
    17881 cacgacggcg cagctcgcgc gctgggcgca cgagcagggc atcccccgcg tcaagatcaa
    17941 gatcggggag tcggccggca cggcgcccgg ccgcgacctg caccgcgtcg ggctcgcccg
    18001 ccgcgtcatc ggggacgccg ccgagctgta tgtggacgcc aacggcggtt acagcgcgaa
    18061 acaggccgtg cggatggagc gccggatgcg cgaccacgac gtgcggtggt tcgaggaacc
    18121 ggtgtcctcc gacgacctgg ccgggctgcg cctggtgcgc gagcgggccg acgccgacgt
    18181 cgcggccggg gagtacggcg gcgacctcgt ctacttcacc cgcatgtgcg cggccggcgc
    18241 ggtcgactgc ctgcagatcg acgccacccg ctgcggcggc tacacgggct ggaacggcgc
    18301 ggccgcgatc gccgccgggc acggcctgga ggtgtcggcg cactgcgcgc ccaacctgca
    18361 cgcgccggtc gccgcggcga cgccgaacct gcgccacatg gagtggttcc acgaccacgt
    18421 gcgcatcgag ggcgacctgt tcgagggcgc ggccgacccg acaggcggcg cggtgcgccc
    18481 gccggacgcg cccggccacg gcctgacgct gcgcgacgac gtggccgagc cgtaccgcgt
    18541 ggcgtagggg gtcagccgtc cgtgtcgagc ggatcgtcga gcagcccggc gtcgtggacg
    18601 agcagggcga tctggacgcg gttgttgagg ccgagcttgg cgaggacgct cgacacgtgc
    18661 gtcttgacgg tggggacgct caggtggagc cgggcggcga tctcggcgtt cggactgccc
    18721 cggccgaccg ccaccgcgac ctcccgctcc cggtcgttga gcagcgccag gcgctccgcg
    18781 gcccgggccc gccgccggtc ctgaccgtcc tcggccaccc gggcgatgag ccgccgggtg
    18841 accgccggcg acaggaccgg atgcccggcg gccacccggc ggatggcgtc gacgatctca
    18901 cccggcgggg tgtccttgag caggaacccg gcggcgcccg cgcgcagggc gcgcagcacg
    18961 tgctcgtcgg cgtcgaaggt ggtcagcacg atcacctcgg gcgcgccgtc gcgggcgcgc
    19021 agcgcctcgg tggcggccag gccgtccatg accggcatcc ggatgtccat cagcaccacg
    19081 tgcggccgcg cccgcccggc catggccagc gcctcggcgc cgtcaccggc ctgggcgagg
    19141 acgcggatgt cgggggcgcc gccgagcatc atcaccaggc cggcccggac cagggggtcg
    19201 tcgtcggcga tgagcacgcc gatcggcgcg gcttctggcg tgatcatgta ggccacggta
    19261 gccaggcccg cacgcgccag ccacccgggc ccccgtcgcc gtcgcgacgc acggacccgt
    19321 gctccagccg gccccccgcc agcgcgacgc gctcggcgag gccggcgagg ccgtggcccc
    19381 caccggcggc gtccggtgcg acggcgtcgg cgggggcgtc gttgaccacc tcgaccgtca
    19441 ggccctcgcc gggagcgccc gtcagccgca ggcggacgcc ggcccccggc gcgtgcttgc
    19501 gggcgttggt cagggcctcc tgcgcgacgc ggtaggcggt gcggcccgtc ccgtccggaa
    19561 ccgtctctcg cgcgccgagg tcgtcgcaca gctcgacccg catgcccgcc tgccccgact
    19621 ccgcgacgag ccgttccaga tcggcgaggg cgggcgggcc gggccgtgtg ggcgaggacg
    19681 cctcgccggt cggggcgcgc agcacgccga tcacctcgcg caggtcctgc agggcctggt
    19741 gggcgctctc cctgatcacc cgcgccgcgc gggcgacgtc ggcggggtcg gcgccggggt
    19801 tgaactccag cgcccccgcg tgcacgctca gcagcgacag ccggtggccg agcacgtcgt
    19861 ggatctcgcg ggcgatggcc tcgcggacct ggtgctgcgc ctgctcggcc cgcagcctcg
    19921 cctcggtctc catccgggcc acgcggtcgc gctgggccag cacgaggcgg cgccggtggt
    19981 ggacgaacag tccccagccg accgccgcgc cctggagggc caggcccagc gtcagcagcg
    20041 cgagcggcgg catgtccgga tcggggcgca gacatgtgaa gacgaccgcg gcgaggacgc
    20101 tgagcccgaa caccgctccg gaggtccgcg ggcggcggtg gaccgcgacc gagaagagcg
    20161 cggccagcat cgggcccgcg accatctcga agacggccga cagcgcgacg agcgtcaccg
    20221 cgagcccgac cggccatctg cggcgcagcc acaacgccgc gcagccgagc atgctcacga
    20281 gctggtcgag ggagaaaagc cacgccggtg gcaggggcgt ggcgtgcaga cgctccaccg
    20341 acgtgtagaa gccgaaggcg acggcgagca cgaacatcgc cgtgtccacg agccagtcgc
    20401 gccggctgcg ccggtgccgg ggggcggcgg agggatccat aacccccgca gcgtacgacc
    20461 cggcggaagg cgcgttcacg gccgcgcggc gaagaccata ccgaagtcgg gcgccgtccg
    20521 acttcggtcg gcggacacgc cgtgcgccgg cgaccttcgc cggacgggag catgccgacg
    20581 cccgatcccc ggcgggtccg ccggtcccta gcgtcggcgc catgcgtaac gtcacccgac
    20641 tcgccggggc gttcctggtc gtcgcgggca tcagcgggac catcgaccac ctggccgtgc
    20701 agccgttctg gggcgcgata ctgaacgtct tcaaccgtca ggtcatcccg cgcctggact
    20761 tcctgaccgg ctacgagatc tacgccaacc ttctcgtcgc cgtcgtcggc gccgtcgtgc
    20821 tcgccgccgc ctggaggcgt gatgacgaag cctgatccgc ggcgtctcgc cctggcggcc
    20881 gcgctgctgg tgctggcacc gatgtgcgcc gaatacgtca ccggctacga cgacagcacg
    20941 ggcgacccgc tcgcgctcgc cgccggactg ctgatcttcg gcccgctgta cggcgcgccc
    21001 gcgctgctga tccgtgagac ggcccg
//
