LOCUS       NZ_JABBXA010000015     22477 bp    DNA     linear   CON 07-NOV-2024
DEFINITION  Microbispora sp. H13382 NODE_15, whole genome shotgun sequence.
ACCESSION   NZ_JABBXA010000015
VERSION     NZ_JABBXA010000015.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora sp. H13382
  ORGANISM  Microbispora sp. H13382
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 206284)
  AUTHORS   Liu,C.
  TITLE     Selective isolation, identification and anti-microbial activity
            study of Microbispora
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 206284)
  AUTHORS   Liu,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-APR-2020) Microbiological Resources Collection Center,
            Sichuan Industrial Institute of Antibiotics, 168 Huaguan Road,
            Chengdu, Sichuan 610052, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014161445.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 07:22:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,982
            CDSs (total)                      :: 7,906
            Genes (coding)                    :: 7,786
            CDSs (with protein)               :: 7,786
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 21 of 121
            Pseudo Genes (incomplete)         :: 104 of 121
            Pseudo Genes (internal stop)      :: 8 of 121
            Pseudo Genes (multiple problems)  :: 11 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:45:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 100775
            Orig. end                         :: 123252
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABBXA010000015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22477
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22477
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22477
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12477](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12477)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(720..729)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.35"
                     /tool="antismash"
     gene            847..1617
                     /locus_tag="HHX41_RS26610"
     CDS             847..1617
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX41_RS26610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_182908195.1"
                     /transl_table=11
                     /translation="MKVAGSIVTALAAWAATGWILAGHPAPAVAGPAGSAVADRAGAAA
                     GTRAARAAADAGGRHMPGIAPRPASDVPGRPAPGLPAVRPPGPGEPTTSGPFGQIVHES
                     RRGPGVVCTYRLRGVHRGGFLNVRDGAGIRHTPVAKLRPADGGFSGACTATNGWIAVKT
                     AGGASGFAAARYLHRLDLGGRPSLSCIYRLRHVRKGSFLNVREGAGVHHAPVGRLRPAD
                     GNIAGACEATRGWLAVDTVAGIPGWASAHYLRRL"
     gene            complement(1726..2550)
                     /locus_tag="HHX41_RS26615"
     CDS             complement(1726..2550)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.5"
                     /locus_tag="HHX41_RS26615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_182908196.1"
                     /transl_table=11
                     /translation="MAEPIVRAAADADMPGLRAVADHYRLLGAWPERPDFVDAEREFGA
                     LLVGEVDGTIAGFGGTLRRGTVTHLGDLFVLPDHQSSGLGRAILSHLLPRDTPKVTFAS
                     DDKRAFALYVRNGMRPRCPLLYLKRGPLGGRPASRESGPAAPGDADVRAAAAMDAHVSG
                     GDRTATLTWYAGLPGVTLHVSGAGYAFARVAGDRVVIGPAGGVTPQDCADIVLEAVNAH
                     PQAGRVHLAVPGTHPLLPLLLEAGWHIGDMDTLMTSDDFMRLDCYTPHPDLG"
     misc_feature    2532..2546
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.56"
                     /tool="antismash"
     gene            complement(2676..3533)
                     /locus_tag="HHX41_RS26620"
     CDS             complement(2676..3533)
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546805.1"
                     /locus_tag="HHX41_RS26620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_169986426.1"
                     /transl_table=11
                     /translation="MSANRHKQSPTSGGPLRSLSLHAIVVITALFVGIPLLYGVLGGFK
                     TTRQLSSNPLGLPDPWMPENYTSVLASASFWRMLWNSTYIAVLTTLVVVAVSAMAAFVF
                     ARFAFRGREALFTMFAAGLMFPFAVAILPLFVLLRMFGLLDNPLGVILPQAAFGMPMTI
                     IILRGFFRAIPGEIEEAAILDGCTSFGFFWRILLPMARPAIATVSVLAVVNSWNQFMLP
                     LVVFSDDSLFTIPLGVQQFQGQYATDIARVMAYIVVAMLPALGFYAVAERQLVSGLTAG
                     AVKG"
     gene            complement(3530..4456)
                     /locus_tag="HHX41_RS26625"
     CDS             complement(3530..4456)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133473.1"
                     /locus_tag="HHX41_RS26625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_169986428.1"
                     /transl_table=11
                     /translation="MKTTRPRSLRLRGFTTILLFLLPALVLFFGLVVAPILLAFYASVF
                     KWNGMRGLPTDFVGMANFTRVLADEVFLGDLWRGLLLIILSVAIQLPLSLGIAMLLNQK
                     IHGRAFFRLLFFAPYVLSEAITAVLFMMILSPTDGLANYILGWFGVDPLDWFADPSTVM
                     MSVFIVMTWKYFGFHMILYIAGRQGIPRELTEAAQIDGATGWKTFRYVTLPLLGPTIRI
                     SVFLSVIGAIQLFDLVWIITGGGPSHSSETMAVTMFQFGFKRFQVGYASAISVVMFFIS
                     LVFALFYQRYVMRRDLEGASTVLRDQR"
     gene            complement(4464..5750)
                     /locus_tag="HHX41_RS26630"
     CDS             complement(4464..5750)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133474.1"
                     /locus_tag="HHX41_RS26630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_182908197.1"
                     /transl_table=11
                     /translation="MKLSRRGAALLAASALVLGGCGSTGNDAGESKSSAGGKVTVEFWN
                     IWTTDPLKSYGAQAIKDFQAKHPNITIKSVPYENEAFKAKLTTLTQSGKAPDIFQTWGG
                     GVLGQQVDAGLVKDLSADTGDWIGTFTDAALSAYQVEGKTYAIPDDIGMVGFWYNKALF
                     KKAGIAEPPGTWSEFVDDVKKLKAAGVTPIALAGKDKWPGHYYWAYLSMRIGGLDALKQ
                     AGESKDFTGPAFVEAGQKLKELAALQPFQKGYLGATYGDPGGQAATMGDGKAAMELMGQ
                     WAPAVQNDAGKGLGDDLGFFPFPAVDGGKGAVTDAFGGGGGFAIGSEAPPEAIEFLKFL
                     TESTEHRKAVATGGLLPVLKGEEDAVTDPNLSVVAKNLAGATGFQLYLDQAYPPAVGQE
                     VNDSVAQLIAGTKTPEQVAQAITETAKSE"
     misc_feature    5746..5761
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    5827..5845
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.38"
                     /tool="antismash"
     misc_feature    5850..5867
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.06"
                     /tool="antismash"
     gene            complement(6111..6710)
                     /locus_tag="HHX41_RS26635"
     CDS             complement(6111..6710)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012854126.1"
                     /locus_tag="HHX41_RS26635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_169986433.1"
                     /transl_table=11
                     /translation="MAFGRSDSPQAPPKMPTAIKLLIAGGFGVGKTTMVGAVSEIRPLR
                     TEETLTDRSVGVDDLSGVEAKSTTTVAMDFGRISIGQDFVLYLFGTPGQERFWFVWDEL
                     ARGALGAVVLADTRRLADCFPSVDYFERRGTPFVVAVNCFEGAPVFDLDEVKLALNLGG
                     DVPIMLCDARKRESGKEVLIELVKHAYGKRPTATAR"
     gene            complement(6691..7065)
                     /locus_tag="HHX41_RS26640"
     CDS             complement(6691..7065)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012854125.1"
                     /locus_tag="HHX41_RS26640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_169986435.1"
                     /transl_table=11
                     /translation="MNAGWHPDEERLLDAPTIRPYVIARGRTEAQDRFDLISLAVTIRP
                     TTGTEIGLDPEHQAIVRLCRRPLSVAEIAAHLDLPAGIVRVLLGDLFDRGFLAVQQPQP
                     ETDVLDERMYKAVLDGLRAL"
     misc_feature    complement(7030..7032)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7062..7484)
                     /locus_tag="HHX41_RS26645"
     CDS             complement(7062..7484)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133477.1"
                     /locus_tag="HHX41_RS26645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_169986437.1"
                     /transl_table=11
                     /translation="MTQKTGASADLAWLLDDLVARIREVEHGIVLSNDGLLLAGSQGLR
                     VEDAEHLSAVASGLQSLARGVGERFQGGPVRQTIVEMKSAYLLVTVAGKGACLAVLCTG
                     DADVGLVAYEMAMLVARVGQYLTSPARTTTGSEVRL"
     gene            complement(7481..9730)
                     /locus_tag="HHX41_RS26650"
     CDS             complement(7481..9730)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133478.1"
                     /locus_tag="HHX41_RS26650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_310742196.1"
                     /transl_table=11
                     /translation="MSLAALWVFAAWVTVRDGLNLAWVAVYDSNVAQPSESLLLELQKE
                     RRLSVSRLVNPALVPSADLAVQRGRTDAAAGEFRRLTRTDIMRFAATDELRRRIDRTFR
                     QLDQLGSARHAVDARQVDRNRAIEAYNDPIDSLFQTYYSLATLDDDELAKDTRTLISLN
                     WARELISREDALLAGVIATGRFGQAEVAQFTQLVGAERNVMDLAQADLEEPLPDVYQRL
                     QKSAALARLHSLEDLVAQQGRPGLRVPVGGEQWQSATSAVLTQLHDVVSGAGEKMIDRA
                     TPVAAGVIIRLVLAGVLGLVAVIASIVLSVTTARALVRQLEKLREAALELANERLPGVV
                     SRLAQGEKVDVKAEAPPLDFGPDVIGQVGAAFNTVQETAIRTAVEEAQLRQSIRDILLS
                     LARRTQSLVHRQLTLLDVMERRESDPAELKDLFRIDHLATRMRRNAENLIVLSGASPAR
                     AWRRSVPMVDVVRGALAEVEDYTRVTVMPMGETALIGRAVGDVIHLLAELIENAVSFSP
                     PYTMVQVGGQAVASGYAIEIEDRGLGMSAEDLEATNQRIADPPEFNLSSTARLGLYVVS
                     RLAERHGIRVSLKASPYGGTTAVVLLPRDLVIEGENDAPEEETGHGLGRREPAARKIAL
                     VGVPDAVPGPVQEVVPVPRAPEPPRPVPSGPPSGGAEPDSLASTGGFTPSGLPFRVPQA
                     NLAPALAEEPRRETGADDEDRSPDDIRKIMGSFQSGTRRGRSEAAKLLGEEEDNL"
     misc_feature    9906..9920
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.89"
                     /tool="antismash"
     misc_feature    complement(9930..9948)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            complement(10001..11587)
                     /locus_tag="HHX41_RS26655"
     CDS             complement(10001..11587)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133479.1"
                     /locus_tag="HHX41_RS26655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_310742184.1"
                     /sec_met_domain="T2TS (E-value: 9.4e-90, bitscore: 295.1,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVGGLTFPKAIDVAAAAAELVADLMVRPWGTVSPSVYETGRLVS
                     LAPWLVGHAERVRFLLDGQRPDGRWGGPDGYALVPTLSATEALLCALSRGDPDRETLSR
                     AAGRGLDWLLGWPPRGAAPLFPDMPAIELIVPALVELVNAHLDTLADRDVPHLAGRPRL
                     RLPPGMNDHTLAAVRSRVGSGAELPQKLMHALETAGPAAHGAPGVQPTSIGTVGASPAA
                     TAAWLGGRALPDPGTAARQHLEAVARRYGGPVPVGLPITVFERGWVLSWLARAGIPFEV
                     PPEMLADLRAAIQPVGTPAGAGLPPDADTTSVALYALALLGMPYEPDSLWAFRTDTHFC
                     TWQGEEGSSVSVNAHVLDALGQYAAVRPEAAERYRSDMDAIGAWLRERQRPEGWWDDRW
                     HASPYYATVSCALALDAFGGAGCASSVRRAVRWVLETQRADGSWGRWGGTREETAYAMQ
                     LLLLTGEDGLVAEAAARGYDYLLGAGEADDPPLWHDKDLYLPGAVVRAAILAALHLAQS
                     SRLVVGRQRQL"
     gene            complement(11584..12477)
                     /locus_tag="HHX41_RS26660"
     CDS             complement(11584..12477)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889881.1"
                     /locus_tag="HHX41_RS26660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="terpene synthase family protein"
                     /protein_id="WP_169986441.1"
                     /sec_met_domain="T1TS (E-value: 2.2e-12, bitscore: 40.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKPTGDELRAARECGAAAAVSAELQRDLRECRDAYPGLFPARPF
                     DSALFSAVAQANAFGAPWASADRLRVASRTALWIFALDWLLDYVAKSRDEVDRLVRGCL
                     DVADGAPPPRDFPLGRFLAELRDELAAAPAFTGLETVWREELRRMLSAMAREWDWKTAA
                     REGTPLPTLDEYLDNADNFGSSFVNVSHWIRGGDPAALGRLEELRTASGQVQRVLRLLN
                     DLATYERDLAWGDLNARMLCSGREEIAERVGVLVDGCGELLEPLRDVCPDEVVYLERQI
                     GYSMGFYGITDYWGGL"
     gene            complement(12495..13859)
                     /locus_tag="HHX41_RS26665"
     CDS             complement(12495..13859)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="HHX41_RS26665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_182908199.1"
                     /sec_met_domain="p450 (E-value: 8.7e-67, bitscore: 219.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIDVDANPIRQARTLPLRQVLPAILRDPVGAVLEIGRESGGDVV
                     RVNLGPFRPYLITHPDHLQHVLRGNSVNYRRDGVLWKPLHRLFGESVMSDGPAWEQSRK
                     VLQPVFTAKNVETLADRMAEAVGEGIGELAPPAESGLPIDVSAAMARIVNRVVMRIFFG
                     DKIDMADAERLAPAFDAVGTSVIFRYLLPFVPYRVPLPGDRAFRNALRTIDEVVVPLVD
                     RHRDRPDDGDDIVSVLCRAGDAGGGPSARWVRDNLVAMLATATETTAGALTWLWPLLGA
                     HPEVAARLRQEIGLVVGNGPVRPAHLADLPYTKQVVQELLRLFPVGWLFPRMVVEPEPL
                     GGVLLKKGETIVVSPFITHRMEAFWERPEEFDPGRFSGRRSTGRHRYAYFPFGGGPHQC
                     LGMHVFMLEAQLIIAGILSRYEILSCSPEVATPQMGASLRPRQRVEITLRPIRRT"
     gene            14452..15555
                     /locus_tag="HHX41_RS26670"
     CDS             14452..15555
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892204.1"
                     /locus_tag="HHX41_RS26670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cellulose binding domain-containing protein"
                     /protein_id="WP_182908200.1"
                     /transl_table=11
                     /translation="MSKRSAVMAALLLVLGLLVARPAEAATVRIMPLGDSITGSPGCWR
                     ALLWNKLQNGGFTNVDMVGTLPAQGCGVPYDGDNEGHGGFLVTNVADQNQLPAWLSATR
                     PDIVMMHFGTNDVWSNRPTATILAAYGKLVDQMRASNPNMKILVAQIIPMNPSTCSECA
                     QRAVALNSAIPGWAASKTTAASPIVVVDQWTGFSTSADTYDGVHPNASGDQKMADKWYP
                     ALSALLGGAQPSPSPGSPSPSPSVSPSVSPSAGPSASPSARPSSSGCAATYTITNQWGG
                     GFQGEVTVKNTGTAAISGWTVTWTFANGQQVTQAWGGKATQSGANVTVKNESWNGSLGA
                     GASTTFGFIASWNTANATLVPGCVASL"
     gene            complement(15734..16648)
                     /locus_tag="HHX41_RS26675"
     CDS             complement(15734..16648)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890631.1"
                     /locus_tag="HHX41_RS26675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_182908201.1"
                     /transl_table=11
                     /translation="MTSSLEGKVALVAGATRGAGRGIAVELGAAGATVYVTGRSTRERR
                     SEMNRPETIEETAELVTAAGGRGIAVPVDHLEREQVRALVERIDAEQGALDVLVNDIWG
                     GELLFSWKDRLWEHSLDDGLRILRLAIDTHIITSHYALPLLIRKPGGLVVEITDGTAEY
                     NAANYRVSFFYDLAKTSVNRMAFGQAKELAPHGATAVSLTPGWLRSEIMLGHYGVTEAN
                     WRDALAQQPHFAISETPAFVGRAVAALAADPEVSRWNGQSLSSGQLAQVYGFTDVDGSR
                     PDCWRYMVEVQDPGLPADVTGYR"
     gene            16736..16969
                     /locus_tag="HHX41_RS26680"
     CDS             16736..16969
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017536936.1"
                     /locus_tag="HHX41_RS26680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_310742185.1"
                     /transl_table=11
                     /translation="MLIAIPEEDGMSEYAATFQLIDADGDGRISAEELVRLMEVLGRPL
                     TPEGAQSAIDKVDADRDGLIDLEEFGAWLSGR"
     gene            17007..18161
                     /locus_tag="HHX41_RS26685"
     CDS             17007..18161
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012855056.1"
                     /locus_tag="HHX41_RS26685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_310742186.1"
                     /transl_table=11
                     /translation="MPAGVARLLRPRMGDVADRMIAEIQRRVPEYARPTDEVYIKVLRL
                     SVNQALRGFLERIENPRAPWDPEVFRTIGRGEAAEGRDLEPFQTAMRLGARVAWRRLTE
                     QSEQLGLDPRTLYDLGEAIFVYLDQLADAAAEGFAAARAHAAGEMERRRRRLLDLLLTR
                     PAAPPEAVADLARAAGWRLPRTVAGVALEEPDDGSPLPVLPPDVLAGLDRNSPCLVVPD
                     PGGPGRVQALESALRGWRAAIGPAVPLAAAANSLGWAREALDLGTRGVLPRQGLLRCAD
                     HMATLVVFKDEDLVAALAEVRLAPLAHLRQTQQDRLAETLLAWLRHGRGVAEVAAALHV
                     HPQTVRYRLRQIEQLYGDALADPDVRFELEIVLRARQARQNPPG"
     gene            complement(18176..19300)
                     /locus_tag="HHX41_RS26690"
     CDS             complement(18176..19300)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013434.5"
                     /locus_tag="HHX41_RS26690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_182908202.1"
                     /sec_met_domain="DAO (E-value: 2.5e-43, bitscore: 142.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSAIVVGAGIWGASLALRLADEGWRVTLVEQYAPGHVRQASAGE
                     TRLLRCAHGSDDWYPRLAWQARDAWRRLEDRTGEDLYVESGLMWFARDPDGWEMRSAGV
                     LERLDIPRELLDPDEAARRFPGLRVDDLAFVLWEPNAGLLRARRATQVTARLAVANGVR
                     QVRARAVPYARKTGVVADGEVLTADRVVWACGAWLPWLFPHEAGHVQVTRQDTFHFGVP
                     RDWTTPPLPAFCDYDLAAYGHGDLDGMGMKITGDAEGEPYDPETGGRRVLRHTEEQARS
                     YLARRFPSLVGAPVVFSQVCQYALTRDAEWIVAEIEDGVWLLGGESGHGFKHAPALAGY
                     VAEILDGRREPDARFGLHERPAARGLRTSGGTTP"
     gene            19395..20048
                     /locus_tag="HHX41_RS26695"
     CDS             19395..20048
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895192.1"
                     /locus_tag="HHX41_RS26695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_249350647.1"
                     /transl_table=11
                     /translation="MMAAESAQTLERGLRLLRLLADANRGRTPTELAHELGLSRPIVYR
                     LLTTLQAEGFARRDAQGRVHLGFGVLVLAQAVHPLLRAAALPALRALAEQAGATAHLTV
                     AEGDEGLAVAVVEPSWTDLHVAYREGSRHPLTRGAAGLALLALRDGRTNPAVHTSRGHL
                     QEGAQGIAAPVPGPPWLEASVGVVSFADLDADKVGPLVLEAAGRLATALSEPPD"
     misc_feature    19434..19436
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(20052..20771)
                     /locus_tag="HHX41_RS26700"
     CDS             complement(20052..20771)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541299.1"
                     /locus_tag="HHX41_RS26700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="uridine kinase"
                     /protein_id="WP_182908203.1"
                     /transl_table=11
                     /translation="MSTAEIHLSVSTWRQPTPAPGSPARTALVRRVAERVLALGTGRLR
                     VGVDGLTAAGKTSFGHELAEHLARAGRPVLRASLDDFKRPWRDRHLYDRESGEGYYRNA
                     YDYDAAIALLLEPAGPGGSGDVALCSIDPLTQVDHSSVRTTAAPGAITIVDGVFAFRPE
                     IDAYWDLRVWMEVTPETSVRRGAERDQDWAGSEAEALHLHRYLPAERIYIAEADPLARA
                     DVVVDNTVFTEPRLLKW"
     gene            20863..22029
                     /locus_tag="HHX41_RS26705"
     CDS             20863..22029
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543629.1"
                     /locus_tag="HHX41_RS26705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="homogentisate 1,2-dioxygenase"
                     /protein_id="WP_182908204.1"
                     /transl_table=11
                     /translation="MPHYRIVGEVPRKRHVQFRAPDGGLYKEELMGEEGFSSDSSLLYH
                     RHAPTAIVKAEAVDAGASGLTPNLPLSPRHFRTQDLRPEGDLVSGRMLLAGNSDVRISY
                     AATDAPSELYRDSMGDECVYVASGRARFESAYGALDVAEGDYVVIPTGTIHRWVPEGPV
                     TALVVEAAGHIRPPKRYLSQYGQFLEHAPYSERDLRAPAEPLLADGAEVPVLVRTRGGL
                     TRLTYAHHPFDVVGWDGCLYPYAFNIQDFEPIVKRTHAPPPVHQTFEGPGFVICSFCPR
                     PLDFHPEAVPIPYNHHNVDSDEFMFYVGGDYTARKGSGIDVGSISLHPAGFTHGPQPGA
                     VEAAVEAVRKGHTETTEMAVMLDTFRPLDLGPAALACEDTDYAWTWAR"
ORIGIN
        1 cgatgcccgc aggccccgtc gtcctgcgga ccgacgaccg ctccgacgcc gtacggctca
       61 cccccggacc gtccggcacc ggcgagggcg cggcgggcac gaggacgggc gacgggggca
      121 cgggcgacgg gggcacgggc gacggaaccg gcggcgggag cacgaccacg gctcccaccg
      181 gtgactggcc ggaactcgac ctcacccggt acggcactcc cgcccccacg ccgtacacgc
      241 tgcggagccg cttcgaccgg gacttcacgc tcgtcctcga ccgggggttc gcgctcgccg
      301 gcggaaagcc ggcctacgcg cacacggtga acggcctcgc cttccccgac atccccacgg
      361 aggtggtcag ggagggcgac ctggtccggc tcaccgtggt caaccgcggc cgggacaccc
      421 acccctggca cctccacggt catcgggtgc tcgtgctctc gcgtgacggc cgctccccca
      481 ccggcagccc gctgtggctc gacaccttcg acgtacggcc gggcgaggtg tgggaggtgg
      541 ccttccgcgc caccaatccc gggctgtgga tgaaccactg ccacaacctc agccacgccg
      601 acctggggat gatgctgcac ctggcgtacg agggggtgac cacgcccttc cacggcgcgc
      661 acggcggatg aagccggcgg cgggaagcgc gatcgccccc ttttccctgg tgtgtcgggt
      721 aaaaaatccg ggcgcgaatt caaccgaggt gtaaacgcag ggtaatcaga tcagaacttc
      781 gggtgagcac cactggcccg ggtccccccg gccgggcgtg ggcgatgccg accgaaggga
      841 gagatcgtga aagtcgccgg aagcatcgtt accgcgctgg cggcgtgggc cgccacgggg
      901 tggatcctcg caggccaccc cgcaccggcg gtcgcgggcc cggccggttc cgccgtggcg
      961 gaccgcgccg gcgcggccgc cgggacccgg gcggcccggg ccgccgcgga cgccgggggc
     1021 cgccacatgc cggggatcgc gccccgcccg gcgtcggatg tcccgggacg tcccgccccg
     1081 ggcctcccgg cggtccggcc acccggtccc ggtgaaccca ccacctcggg accgttcggg
     1141 cagatcgtgc acgaaagcag gcgggggccc ggtgtcgtgt gcacctaccg gctccggggc
     1201 gtgcacaggg gaggcttcct caacgtccgt gatggcgccg gaatacgcca cacccccgtc
     1261 gccaaactgc gaccggccga cggaggcttc tcgggagcct gcaccgccac caacggctgg
     1321 atcgcggtga agaccgccgg cggggcgtcg ggcttcgccg ccgcccgcta cctccacagg
     1381 ctcgacctcg gcgggcggcc ctcgctttcg tgcatctacc gcctccggca cgtgcgcaag
     1441 ggcagcttcc tcaacgtccg cgagggcgcc ggcgtccacc acgcccccgt gggcaggctg
     1501 cgaccggccg acgggaacat cgccggagcc tgcgaggcca cccgcggctg gctggccgtc
     1561 gacaccgtcg ccggcattcc cggatgggcc tccgcccact atctgcggag gctgtgaccc
     1621 cgaccggcgg gctccgtcct gccgcgtccc cccggccgct gtcctcgtcc ccggtgtccc
     1681 cctggccggg gacgggggcc gccggcccgc cgccccggct ccggtctagc cgaggtcggg
     1741 atgcggggtg tagcagtcga gccgcatgaa gtcatcgctg gtcatcagcg tgtccatgtc
     1801 gccgatgtgc cagcccgcct ccagcagcag gggcagcagc ggatgcgtgc cgggcaccgc
     1861 caggtgcacc cgcccggcct ggggatgcgc gttcaccgcc tccagcacga tgtcggcgca
     1921 gtcctggggg gtcacacccc cggcaggccc gatgacgacc ctgtctccgg ccaccctggc
     1981 gaacgcgtag cccgccccgc tgacgtgcag ggtcacgccg ggcaggccgg cgtaccacgt
     2041 cagcgtcgcg gtccggtccc cgccggagac gtgagcgtcc atggccgccg ccgcgcggac
     2101 gtccgcatcc cccggcgccg ccggcccgct ctcccgcgac gcgggccggc cgccgagcgg
     2161 cccccgcttg aggtacagca gcgggcagcg cgggcgcatc ccgttcctga cgtacagcgc
     2221 gaaggccctc ttgtcgtcgg acgcgaaggt gaccttgggt gtgtcgcgcg gcagcaggtg
     2281 ggacaggatc gcgcggccca gccccgacga ctggtggtcc gggaggacga acaggtcgcc
     2341 gaggtgcgtg accgtccccc ggcgcaacgt gccgccgaag cccgcgatcg tgccgtccac
     2401 ctcgccgacg agcagcgcgc cgaactcgcg ttcggcgtcc acgaagtccg gccgctccgg
     2461 ccacgcgccc aggaggcggt agtggtcggc gacggcccga agtccgggca tgtcggcgtc
     2521 ggccgcggca cggacgatcg gttccgccat cggtgctccc ccctgcgcgt tctcccctcg
     2581 tccgttcacc ttagggcgcg ttcatccccc agttcccggc cggggcggcc gaaccgggac
     2641 gtggccgggc ggagcaggtg gaggacgcgt gcggatcagc ccttgacggc ccccgcggtc
     2701 aggccgctga cgagctggcg ctcggccacg gcgtagaagc cgagggcggg cagcatcgcg
     2761 accacgatgt aggccatgac ccgcgcgatg tccgtcgcgt actgcccctg gaactgctgg
     2821 acgcccagcg ggatggtgaa gagactgtcg tcgctgaaca ccacgagtgg cagcatgaac
     2881 tggttccagc tgttgacgac cgccagcacg gagaccgtgg cgatcgcggg ccgggccatc
     2941 ggcagcagga tccgccagaa gaagccgaat gacgtgcacc cgtcgaggat cgccgcctcc
     3001 tcgatctccc ccgggatggc ccggaagaag ccacgaagga tgatgatcgt catcggcatg
     3061 ccgaaggccg cctgcgggag gatcacgccg agcgggttgt cgagcagccc gaacatccgc
     3121 agcagcacga acagcggcag gatcgccacc gcgaacggga acatgagccc ggcggcgaac
     3181 atcgtgaaca gcgcctcgcg cccccggaag gcgaaccgcg cgaacacgaa ggccgccatc
     3241 gcggacaccg cgacgaccac gagcgtggtc agcaccgcga tgtacgtgct gttccagagc
     3301 atgcgccaga acgacgcgga agccagcacg ctcgtgtagt tctccggcat ccacgggtcg
     3361 ggcaggccca gcgggttgct cgacagctgc cgggtggtct tgaagccgcc gagcacgccg
     3421 tacagcagcg ggatgccgac gaacagcgcc gtgatcacga cgatcgcgtg cagggacagg
     3481 ctgcgcagcg gaccgcccga cgtcggagac tgcttgtgac ggttcgcgct catcgctggt
     3541 ccctcagcac ggtgctcgct ccttcgaggt cgcggcgcat gacgtatctc tggtagaaga
     3601 gcgcgaacac gaggctgatg aagaacatca ccacgctgat cgcactcgcg tagccgacct
     3661 ggaagcgttt gaagccgaac tggaacatcg tgacggccat ggtctcggag gagtgcgacg
     3721 ggcctccacc ggtgatgatc cagaccaggt cgaacagctg gatcgcaccg atgaccgaca
     3781 ggaacacgct gatgcggatc gtcgggccga gcagcggcag cgtgacgtag cggaaggtct
     3841 tccagcccgt cgcgccgtcg atctgggcgg cctcggtgag ctcccgcggg atgccctggc
     3901 gtccggcgat gtacagaatc atgtggaaac cgaagtattt ccaggtcatg acgatgaaca
     3961 ccgacatcat gaccgtcgac gggtcggcga accagtcgag cgggtcgact ccgaaccagc
     4021 cgaggatgta gttggccagg ccgtcggtgg gcgacaggat catcatgaac agaaccgcgg
     4081 tgatcgcctc ggacagcacg tacggggcga agaacaacag gcggaagaac gccctgccgt
     4141 ggatcttctg gttgagcagc atggcgatgc ccagcgagag gggaagctgg atcgccaccg
     4201 acaggatgat cagcagcagg ccgcgccaca ggtcacccag gaagacctcg tccgccagca
     4261 cacgggtgaa gttggccatg ccgacgaagt ccgtcggcag cccgcgcatg ccgttccact
     4321 tgaagacgct cgcgtagaag gcgagcagga tcggcgccac gacgagcccg aagaagagca
     4381 cgagggcggg gagcaggaac aggaggatcg tggtgaaccc ccggagcctg aggctccggg
     4441 gtctcgtcgt cttcacgcgg cagttactcc gacttcgccg tttccgtgat ggcctgcgcc
     4501 acctgctcgg gcgtcttggt cccggcgatc agctgggcca cggagtcgtt gacctcctgg
     4561 ccgacggccg gcgggtacgc ctggtcgagg tagagctgga acccggtggc cccggcgagg
     4621 ttcttcgcca ccacgctcag gttcgggtcc gtgaccgcgt cctcctcgcc cttcagcacc
     4681 gggagcaggc cgccggttgc gacggccttg cggtgctcgg tgctctcggt gaggaacttc
     4741 aggaactcga tcgcctcggg cggagcctcc gacccgatcg cgaagccgcc gccgccgccg
     4801 aaggcgtcgg tgaccgcgcc cttgccgccg tccacggccg ggaaggggaa gaagccgagg
     4861 tcgtcgccca ggcccttgcc ggcgtcgttc tggaccgcgg gcgcccactg gcccatcagc
     4921 tccatcgcgg ccttgccgtc acccatggtc gcggcctgac cgcccgggtc gccgtacgtc
     4981 gcgcccaggt agcccttctg gaacggctgg agagcggcca gttccttcag cttctgcccc
     5041 gcctccacga aggccggacc ggtgaagtcc ttgctctcgc ccgcctgctt gagggcgtcg
     5101 aggccaccga tgcgcatgga gaggtacgcc cagtagtagt ggccgggcca cttgtccttg
     5161 ccggcgaggg cgatcggggt gactcccgcc gccttcagct tcttgacgtc gtcgacgaac
     5221 tccgaccagg tccccggggg ctcggcgatc ccggccttct tgaacagcgc cttgttgtac
     5281 cagaagccca ccatgccgat gtcgtccggg atggcgtacg tcttgccctc gacctggtag
     5341 gccgacagcg cggcgtcggt gaaggtgccg atccagtcac cggtgtcggc gctcaggtcc
     5401 ttgaccaggc ccgcgtcgac ctgctggccg agcacgccgc cgccccaggt ctggaagatg
     5461 tccggcgcct tgccggactg cgtgagcgtc gtcagcttcg ccttgaacgc ctcgttctcg
     5521 tagggaacgc tcttgatggt gatgttcggg tgcttggcct ggaagtcctt gatcgcctga
     5581 gcgccgtagc tcttcagggg gtccgtggtc cagatgttcc agaactcgac ggtcaccttg
     5641 ccgccggctg agctcttgct ctcgccggcg tcgttcccgg tactaccaca tcccccgagg
     5701 accagtgctg acgccgccag gagcgccgca cctcgccgac tcaacttcac ggtggtttcc
     5761 cttctggatt ccgaccgaaa ctttcggctt gcgcccgata gtttcgcgat gtggcgtacg
     5821 ttacagtggg gtaaggctca gatcaacggc tgttgtccac ctgttacgca tggtcggcgg
     5881 cgatggacaa gacgatcggc tcatggcgcc caaaagggat gaataggcag taatcaggcg
     5941 gcattaacgg acagccgaaa ccagggcggg gcccagccgg ggaatgggcg acgcgcggag
     6001 gcgtgtacga aaacaccgct cgccacgaaa cgtaaactcg cgcacagcag tcataagcca
     6061 tgcacgcgga ggaacccgga cgttgccggg tgaggatgcg acgaaaaacg tcagcgggcg
     6121 gtggcggtgg gacgctttcc gtaggcgtgc ttgacgagct cgatcaggac ttccttgccc
     6181 gattcccgct tgcgcgcgtc gcacagcatg atcggcacgt ccccgccgag gttgagggcg
     6241 agcttgacct cgtccaaatc gaagaccggg gcgccctcga agcagttgac cgcgacgacg
     6301 aagggcgtgc cgcgccgctc gaagtagtcg acggagggga agcagtcggc gagcctgcgg
     6361 gtgtcggcca gcacgaccgc gccgagcgct ccccgggcga gctcgtccca gacgaaccag
     6421 aaccgctcct ggccgggggt gccgaagaga tagaggacga agtcctgccc gatgctgatc
     6481 cggccgaagt ccatggccac cgtggtggtg gacttcgcct cgaccccgga caggtcgtcc
     6541 acgccgacgc tgcggtcggt cagcgtctcc tccgtgcgca gcggccggat ctccgacacc
     6601 gcgccgacca tcgtcgtctt gcccaccccg aaacccccgg cgatcagcaa cttgatcgcc
     6661 gtgggcatct tcgggggggc ctgcggcgaa tcagagcgcc cgaaggccat cgagcaccgc
     6721 cttgtacatc cgctcgtcga gcacgtccgt ctccggttgg ggctgctgca cggccaagaa
     6781 accccggtcg aacaggtcgc cgaggaggac ccggacgatc ccggccggca ggtccagatg
     6841 ggccgcgatc tccgcgaccg acagcggcct gcggcacagc cgcacgatcg cctggtgctc
     6901 ggggtccagt ccgatctccg tccccgtggt gggccggatc gtcaccgcga gcgagatgag
     6961 gtcgaagcgg tcctgcgcct ccgtacggcc gcgtgcgatc acgtacggcc ggatggtcgg
     7021 cgcgtcgagt aagcgctcct cgtccgggtg ccatccggcg ttcacaggcg gacctcgctc
     7081 cccgtcgtgg tgcgggcggg cgaggtgagg tactgcccga cgcgcgcgac gagcatggcc
     7141 atctcgtagg ccaccaggcc gacgtcggcg tctcccgtgc agagcacggc caggcaggcg
     7201 cccttgcccg ccacggtcac gagcaggtag gccgacttca tctccacgat ggtctgccgt
     7261 acgggcccgc cctggaagcg ctcgccgaca ccgcgcgcga ggctctgcag gccggaggcg
     7321 acggcggaca ggtgctcggc gtcctccacg cgcaggccct gcgagccggc cagcagcagg
     7381 ccgtcgttgg acagcacgat gccgtgctcc acctcacgga tccgtgcgac gaggtcgtcg
     7441 agcagccacg cgaggtccgc ggaggccccg gtcttctgcg tcacaggttg tcctcctctt
     7501 cgccgagcag cttcgcggcc tcggacctgc cgcgcctcgt ccccgactgg aacgagccca
     7561 tgatcttacg gatgtcgtcg ggcgagcggt cctcgtcgtc cgccccggtc tcgcgcctcg
     7621 gctcctcggc gagcgcgggg gcgaggttcg cctgcggcac ccggaacggc agccccgacg
     7681 gggtgaaccc gccggtggac gcgagcgagt ccggctcggc accgccggag ggtggcccgc
     7741 tcggcacggg cctgggcggc tcgggagccc tcggcacggg aaccacctcc tgcactggtc
     7801 cgggaaccgc gtcgggcacg cccaccaggg cgatcttccg agcagcgggc tcccgccgtc
     7861 cgagaccgtg accggtctcc tcctccggcg cgtcgttctc gccctcgatg acgaggtcgc
     7921 ggggcagcag cacgaccgcg gtcgtgccgc cgtacggcga cgccttgagc gacaccctga
     7981 tgccgtgccg ctcggccagg cggctgacga cgtacagccc gagcctggcg gtgctcgaca
     8041 ggttgaactc gggcgggtcg gcgatccgct ggttggtcgc ctccaggtcc tcggcgctca
     8101 tcccgaggcc gcggtcctcg atctcgatcg cgtacccgct ggccaccgcc tggccgccca
     8161 cctgcaccat ggtgtacggc ggggagaacg acaccgcgtt ctcgatcagc tcggcgagca
     8221 ggtggatgac gtcgcccacc gcgcgtccga taagcgcggt ctcccccatc ggcatcacgg
     8281 tgacgcgggt gtagtcctcg acctccgcca gcgcgccgcg cacgacgtcg accatcggca
     8341 ccgagcgccg ccacgcgcgg gcgggggacg ccccggacag gacgatgagg ttctccgcgt
     8401 tgcgccgcat gcgggtggcg aggtggtcga tgcggaacag gtccttcagc tcggccgggt
     8461 ccgactcgcg ccgctccatc acgtcgagca gcgtgagctg gcggtgcacg agcgactgcg
     8521 tccgccgggc gaggctgagc aggatgtcgc ggatgctctg ccggagctgg gcctcctcga
     8581 cggcggtgcg gatcgcggtc tcctgcacgg tgttgaacgc cgcacccacc tggccgatga
     8641 cgtcgggccc gaagtcgagc ggcggcgcct cggccttgac gtcgaccttc tcgccctggg
     8701 cgagccggga gaccaccccg ggcagccgct cgttggccag ctcgagcgcg gcctcgcgca
     8761 gcttctccag ctggcgcacc agcgcccggg ccgtggtgac cgacaggacg atcgacgcga
     8821 tgaccgccac gaggccgagc acacccgcca gcaccagccg gatgatgacg ccggcggcga
     8881 cgggggtcgc ccggtcgatc atcttctcgc ccgcgccgct gaccacgtcg tgcagctggg
     8941 tcaggacggc cgacgtcgcc gactgccact gctctccgcc gacgggcacg cgcaggccgg
     9001 gccggccctg ctgcgcgacc agatcctcca ggctgtggag ccgggcgagc gcggcgctct
     9061 tctgcagccg ctggtagacg tcgggaagcg gctcctccag gtcggcctgc gcgaggtcca
     9121 tcacgttgcg ctcggcgccg acgagctggg tgaactgggc gacctccgcc tggccgaacc
     9181 tgcccgtcgc gatgacgccg gccaaaagcg cgtcttcacg cgagataagt tcccgtgccc
     9241 agttgaggct gataagtgtc cgcgtgtctt tcgcgagctc gtcgtcgtcg agcgtggcga
     9301 gcgaatagta ggtctggaag agggagtcga tggggtcgtt gtaggcctcg atggccctgt
     9361 tccggtccac ctggcgcgcg tccaccgcgt gccgcgcgga accgagctgg tcgagctgcc
     9421 ggaacgtgcg gtcgatccgt ctccggagtt cgtcggtcgc cgcgaaccgc atgatgtcgg
     9481 tcctcgtgag cctgcggaac tcgcccgcgg cggcgtccgt acggccgcgc tgcacggcga
     9541 ggtcggcgga cgggaccagc gccgggttca ccaggcggga gaccgacagg cgccgctcct
     9601 tctgcagctc cagcaacagg gactcactcg gctgggcgac gttgctgtcg tagaccgcca
     9661 cccacgcgag gttgagaccg tcccgcacgg tcacccacgc ggcgaagacc cacagggccg
     9721 caagcgacac gagcaaggcc gtgactttgg tccgcacgcg cgagttgcgg aagcgcataa
     9781 cacccaccaa gggacatatg aagagccgtc atagcgcgtt tcccggcgat taaccagaag
     9841 ctcatcgcta gggcggcgga catcgcccaa cattttatag ccgcgccacg ccccgccacc
     9901 ctagcaatgg acagaaaatc gctcaaggcc gcattatgta cgccatttgg ggcaaatgta
     9961 cgaatgtatg cctatatagc gtgatcaagc gacccgttga tcatagttga cgctgcctgc
    10021 cgacaacaag tcgactggac tgtgcgaggt gcagggcggc gaggatcgcg gctctgacca
    10081 ccgcacccgg taggtagagg tccttgtcgt gccacagcgg cggatcgtcg gcctcgcccg
    10141 ctccgagtag gtagtcgtac cctctggctg cagcctccgc gacgagcccg tcctccccgg
    10201 taagcagcag cagttgcatg gcgtaggccg tctcctcccg ggtgccgccc cagcggcccc
    10261 aggatccgtc ggcccgctgg gtctccagca cccatcgcac ggcccgccgt acggaggacg
    10321 cacagccggc gccgccgaag gcgtccagcg ccagcgcgca ggagacggtc gcgtagtagg
    10381 gcgaggcgtg ccagcggtcg tcccaccagc cctccggccg ctggcgctcg cggagccagg
    10441 ccccgatcgc gtccatgtcg gaccggtagc gctcggcggc ctccggccgc accgccgcgt
    10501 actgccccag cgcgtcgagc acgtgggcgt tcacgctgac cgacgacccc tcctccccct
    10561 gccaggtgca gaagtgggtg tccgtgcgga aggcccacag gctgtccggc tcgtacggca
    10621 tgccgaggag cgcgagggcg tacagggcga ccgacgtggt gtcggcgtcc ggcggcagac
    10681 cggcgccggc gggcgtgccg accggctgga tcgcggcccg caggtccgcc agcatctccg
    10741 gcggcacctc gaaggggatc cccgcgcggg cgagccagct cagcacccag ccgcgctcga
    10801 agaccgtgat cggaaggccc accgggaccg gcccgccgta ccgtcgcgcg accgcctcca
    10861 ggtgctgcct ggccgcggtg cccggatccg gcagcgcacg gccgccgagc caggcggcgg
    10921 tggcggccgg ggacgcgccg acggtgccga tcgaggtcgg ctggacgccc ggggccccgt
    10981 gggcggcggg accggccgtc tccagcgcgt gcatgagctt ctgcggcagt tccgcgcccg
    11041 agccgaccct cgacctgacc gcggcgagcg tgtggtcgtt catgcccggg ggcagccgca
    11101 gcctcgggcg tccggcgaga tgcggcacat cccggtcggc cagcgtgtcc aggtgcgcgt
    11161 tgaccagctc gaccagcgcg ggcacgatca gctcgatcgc cggcatgtcg gggaacagcg
    11221 gcgcggcgcc ccgcggcggc cagccgagca gccagtccag ccctcggccg gccgcccgcg
    11281 agagcgtctc ccgatcgggg tccccccgcg acagcgcgca caagagcgcc tcggtcgcgc
    11341 tcaacgtggg gacgagggcg tacccgtccg gcccgcccca gcggccgtcg ggccgctggc
    11401 cgtccagcag gaaccgcacc cgttccgcgt ggcccaccag ccacggcgcc aggctcacca
    11461 gccgcccggt ctcgtacacg gagggggaga ccgtgcccca cggccggacc atgagatcgg
    11521 cgaccagttc ggcggccgcg gccgccacgt cgatcgcctt ggggaaagtc aggccgccga
    11581 cgctcacagc ccgccccagt agtcggtgat cccgtagaag cccatgctgt acccgatctg
    11641 cctttccaga tagaccacct cgtccgggca gacgtcgcgc agcggctcca ggagctcgcc
    11701 gcacccgtcc accaggacgc cgacgcgttc ggcgatctcc tcccggcccg agcagagcat
    11761 ccgcgcgttg agatcgcccc aggcgaggtc ccgctcgtac gtggccaggt cgttgagcag
    11821 gcggaggacg cgctgcacct ggccgctcgc ggtccgcagc tcctcgagcc ggccgagcgc
    11881 ggccgggtct ccgccccgga tccagtggga cacgttgacg aaggacgagc cgaagttgtc
    11941 cgcgttgtcg aggtactcgt ccagggtcgg cagcggcgtc ccctcgcggg cggccgtctt
    12001 ccagtcccac tcccgcgcca tggccgacag catgcgccgc agctcctccc gccagacggt
    12061 ctccagcccg gtgaacgcgg gcgccgcggc gagctcgtcc cggagctcgg cgaggaatcg
    12121 gcccaggggg aagtcccgcg gcggcggtgc gccgtccgcc acgtccaggc acccgcggac
    12181 gaggcggtcc acctcgtccc gtgacttcgc cacgtagtcg agcagccagt cgagcgcgaa
    12241 gatccacagc gccgtacggc tcgcgacgcg caaccggtcc gcgctcgccc acggcgcccc
    12301 gaacgcgttc gcctgcgcga ccgcgctgaa cagcgccgag tcgaacggcc gcgccgggaa
    12361 gaggccgggg taggcgtccc ggcactcgcg cagatcccgc tggagctcgg cggacacggc
    12421 ggcggcggca ccgcactccc tcgccgcccg gagctcgtct cctgtcggct tcgtcatgtg
    12481 catggatgtc ccggtcaggt acgacggatg gggcgcaggg tgatctcgac ccgctggcgc
    12541 ggccgcagcg aggcccccat ctggggcgtc gccacctccg ggctgcagga gaggatctcg
    12601 tagcggctga ggatgcccgc gatgatcagc tgggcctcga gcatgaagac gtgcatgccg
    12661 agacactgat gagggccccc gccgaacggg aagtacgcgt acctgtgccg gcccgtggac
    12721 cggcgcccgg agaagcggcc ggggtcgaac tcctccggcc gctcccagaa cgcctccatg
    12781 cggtgggtga tgaacgggct gacgacgatc gtctcgccct tcttgagcag cactcccccg
    12841 aggggctccg gctcgacgac catgcggggg aacagccagc ccacggggaa cagccgcagg
    12901 agttcctgca cgacctgctt cgtgtacggc aggtccgcca ggtgggcggg tcgtacgggt
    12961 ccgttcccga ccacgaggcc gatctcctgc cgcaacctcg cggccacctc gggatgcgcc
    13021 cccaggaggg gccacagcca ggtgagcgcg cccgccgtgg tctcggtggc ggtggccagc
    13081 atggcgacca ggttgtcgcg cacccatcga gcgctcggtc cgccgccggc gtccccggcc
    13141 cggcacagga ccgagacgat gtcgtcgccg tcatcgggcc tgtccctgtg cctgtccaca
    13201 agcggaacca cgacctcgtc gatcgtccgc agggcgttcc tgaaggcgcg gtctcccggg
    13261 agcgggacgc ggtaggggac gaacggcagc aggtagcgga agatgacgga cgtgccgacc
    13321 gcgtcgaagg ccggggcgag ccgctcggca tcggccatgt cgatcttgtc gccgaagaag
    13381 atccgcatca cgaccctgtt gacgatccgc gccatcgccg cggagacgtc gatcgggagg
    13441 cctgactcgg cgggtggggc gagctcgccg atcccctcgc cgaccgcctc cgccatgcgg
    13501 tccgcgagcg tttccacgtt cttggcggtg aacacgggct gcagaacctt gcggctctgc
    13561 tcccacgcgg ggccgtcgga catgacgctc tccccgaaga gccggtgcag cggcttccag
    13621 aggacgccgt cacgccggta gttcacggag ttgccgcgca ggacgtgctg caggtgatcg
    13681 gggtgtgtga tcaggtacgg ccggaaggga cccaggttca ccctgacgac gtcgccaccg
    13741 gactcccggc cgatctcgag gacggcgccg accggatcgc ggaggatcgc gggaagtacc
    13801 tgccggaggg gaagagttct cgcttgtcgg atcgggttcg cgtcaacatc gatcggcatt
    13861 ccggcttgct ccccacctga cgatcacgcc gttcgcgaag tatcacatga tccacgccga
    13921 ttgatcaatg ttgcggcgag tgacaatttt gtcctgtgag gcgagagatg ctccgatggc
    13981 gcattttgcc cgcatagtga cgtgtgacac gttttggggg cgtgaaaaaa gggaagggcc
    14041 ggacctcgcg gcccggccct cctcaggacg tgtcgtcagg agtgactggt caccagcagc
    14101 gcgaggccca caaggatgac gatgggaatc agccacacca cgacctcgcc gaggaactcc
    14161 ttgtacatgg ggaccgatcc tcccggtgac gtgcgaaaag tagaccgacg tgcagcatat
    14221 tcggtcgtgc ggccaggggg aacccggcgt cgccgcgggc gatgaacgag gggcggctgc
    14281 gccccggagt atccagtgag gccggccggc gacgcgaccg ccgaccggct gattcatggg
    14341 atgaaacgta catacatccc cgctggtcag ggcatttgcg gcgtctcgac cctgggccgg
    14401 gcggcggacc gctctctacc atcgcgccgg acagcacgag ggagagacgc gatgtcgaag
    14461 agaagtgcgg tgatggcggc cctgctcctg gtgctcgggc tgctcgtcgc ccggcccgcc
    14521 gaggcggcca cggtgcggat catgcccttg ggcgactcga tcaccggatc gcccggctgc
    14581 tggcgggccc tgctgtggaa caagctgcag aacggcggct tcaccaacgt cgacatggtg
    14641 ggaacgctgc ccgcccaggg gtgcggggtg ccgtacgacg gcgacaacga aggccacggc
    14701 ggcttcctcg tcacgaacgt cgccgaccag aaccagctcc cggcctggct ctcggcgacc
    14761 cgtcccgaca tcgtgatgat gcacttcggc accaacgacg tgtggagcaa caggcccacc
    14821 gccacgatcc tcgcggcgta cggcaagctc gtggaccaga tgcgggcgag caacccgaac
    14881 atgaagatcc tcgtcgccca gatcatcccg atgaacccga gcacctgctc cgagtgcgcc
    14941 cagcgggccg tcgccctgaa cagcgcgatt ccgggctggg ccgcctcgaa gaccacggcg
    15001 gcctccccga tcgtggtcgt cgaccagtgg accggtttca gcacgagcgc ggacacctac
    15061 gacggcgtcc accccaacgc gagtggcgac cagaagatgg cggacaagtg gtatcccgcc
    15121 ctgtcggcgc tgctcggcgg cgcgcagccg tccccgagcc ccggatcccc cagccccagc
    15181 cccagcgtga gccccagtgt gagccccagt gccggcccgt cggcgtcgcc ctcggcacgg
    15241 cccagttcct ccggctgcgc cgcgacctac acgatcacca accagtgggg cggcggcttc
    15301 cagggtgagg tcacggtcaa gaacacgggc accgctgcga tcagcggctg gaccgtgacc
    15361 tggaccttcg ccaacgggca gcaggtcacc caggcgtggg gcggcaaggc cacccagagc
    15421 ggggcgaacg tgaccgtgaa gaacgagagc tggaacggct ccctcggtgc cggcgcgagc
    15481 acgaccttcg gcttcatcgc ctcctggaac accgcaaacg ccacactggt gccgggctgc
    15541 gtggcgtccc tctgacctcg gccgggcgtg acctgtgctc ggcagcgggg agaggccaca
    15601 gaccgcactg ggtggcgggc acggcgggcg gcaccgcggc cgaggtccac gtcgagtgga
    15661 cctcggcacc gccgccctcg gcacccgttg atcggtacag gccacctcgc gaagcgccgc
    15721 ggcggcttcc gcgtcagcgg taaccggtga cgtcggcggg gaggccgggg tcctggacct
    15781 ccaccatgta tcgccagcag tccgggcggc tgccgtcgac gtcggtgaag ccgtacacct
    15841 gcgccagttg gccgctggac aacgactgcc cgttccagcg gctcacctcc gggtcggcgg
    15901 ccagggccgc caccgcgcgg cccacgaagg ccggggtctc ggagatcgcg aagtgcggct
    15961 gctgggccag cgcgtcgcgc cagttggcct ccgtcacccc gtagtgcccc agcatgatct
    16021 ccgaacggag ccagcccggc gtgagcgaga ccgcggtcgc accgtgcggc gccagctctt
    16081 tcgcctggcc gaacgccatg cggttcacgg acgtcttcgc gaggtcgtag aagaacgaga
    16141 cgcggtagtt ggcggcgttg tactccgccg tgccgtcggt gatctcgacc accaggccgc
    16201 ccggcttgcg gatcagcagc ggcagcgcgt agtggctggt gatgatgtgc gtgtcaatcg
    16261 ccagccgcag tatgcgcagg ccgtcgtcga gtgagtgctc ccagagccgg tccttccagc
    16321 tgaacagcag ctcgccgccc cagatgtcgt tgaccagcac gtcgagcgcg ccctgctcgg
    16381 cgtcgatccg ctccacgagg gcccgcacct gctcgcgctc caggtggtcg accggcacgg
    16441 cgatgccccg cccgccagcg gcggtgacca gttcggccgt ctcctcgatc gtctccggcc
    16501 ggttcatctc cgaacgccgc tcgcgggtgc tgcggccggt cacgtagacc gtcgcccccg
    16561 cggcgcccag ctcgaccgcg atgccgcggc ccgcaccccg ggtcgccccg gcgaccagtg
    16621 cgaccttccc ctcaaggctg ctcgtcatga ccgtcatgct ggcagacgcc accgacagaa
    16681 acggcttccg ccggttggcc gcgatctctg ggggcagcgc gtgctttcag ctagtgtgct
    16741 gatcgcgatc ccggaggagg acggcatgag cgaatatgcg gcgacttttc aacttatcga
    16801 cgccgatggg gacgggcgaa tctccgccga ggagctcgta cgcctgatgg aggtgctcgg
    16861 ccggccgctc acgccggaag gcgcgcagag cgccatcgac aaggtcgacg ccgaccgcga
    16921 cggcctgatc gacctggagg agttcggcgc ctggctgagc gggcgctgag cggacgctga
    16981 agggcgacga cgagttctgg gacgcggtgc ccgcgggcgt cgcgaggctg ctgcgtcccc
    17041 gcatgggcga cgtcgcggac cggatgatcg cggagatcca gcggcgggtg cccgaatacg
    17101 cccgcccgac ggacgaggtc tacatcaagg tcctgcggct gtcggtcaac caggcgctgc
    17161 gggggttcct cgaacgcatc gagaacccgc gggcgccgtg ggaccccgag gtcttccgga
    17221 cgatcggcag gggtgaggcc gccgaggggc gcgacctgga gcccttccag accgcgatgc
    17281 ggctgggcgc gcgggtggcg tggcggaggc tcaccgagca gtccgagcag ctgggcctcg
    17341 acccgcggac gctgtacgac ctcggcgagg ccatcttcgt ctacctcgac cagctcgccg
    17401 acgccgcagc ggagggcttt gccgcggcgc gggcgcacgc ggccggcgag atggagcgcc
    17461 gccgccggcg gctgctcgac ctgctgctga cccggcccgc ggccccgccg gaggccgtcg
    17521 ccgacctggc cagggcggcc ggctggcggc tcccccgcac ggtcgcggga gtggccctgg
    17581 aggaacccga cgacggttct cccctgccgg tgctgccgcc ggacgtgctg gccgggctcg
    17641 accggaactc cccgtgtctc gtggtgccgg accccggcgg ccccgggcgg gtgcaggcgc
    17701 tggagagcgc cctgcgcggc tggcgggccg cgataggccc cgccgtgccg ctcgccgcgg
    17761 ccgcgaactc gctcggctgg gcgagggagg ccctcgacct cggcacccgg ggcgtcctcc
    17821 cccggcaggg actgctgcgc tgtgccgacc acatggcgac gctggtcgtc ttcaaggacg
    17881 aggacctcgt ggccgcgctg gcggaggtgc gtctcgcgcc cctcgcccac ctgcgccaga
    17941 cccagcagga ccgcctggcc gagaccctgc tcgcctggct gcgccacggc cggggcgtcg
    18001 ccgaggtcgc cgcggcgctc cacgtccacc cgcagaccgt gcgctaccgg ctgcgccaga
    18061 tcgagcagct gtacggcgac gcgctcgccg atcccgacgt ccggttcgag ctggagatcg
    18121 tcctgcgcgc ccggcaggcc cgtcagaacc cgcccggcta gccctctcta cggctctacg
    18181 gcgtggtgcc gccgctggtg cgcagacccc gggccgccgg ccgctcgtgc aggccgaacc
    18241 gcgcgtccgg ctcccgccgg ccgtcgagga tctccgcgac gtagccggcg agggccgggg
    18301 cgtgcttgaa gccgtgcccg gactcgccgc cgagcagcca gacgccgtcc tcgatctccg
    18361 cgacgatcca ctcggcgtcc ctggtcagcg cgtactggca gacctggctg aacaccaccg
    18421 gcgctcccac cagcgagggg aaccgcctgg ccaggtagga gcgcgcctgc tcctcggtgt
    18481 gccgcagcac ccgcctgccg ccggtctccg ggtcgtacgg ctcgccctcg gcgtcgccgg
    18541 tgatcttcat gcccatgccg tccaggtcgc cgtgcccgta cgccgccagg tcgtagtcgc
    18601 agaaggcggg cagcggcggc gtggtccagt ctctgggcac gccgaagtgg aaggtgtcct
    18661 gccgcgtcac ctggacgtgt cccgcctcgt gcgggaacag ccacggcagc cacgcgccgc
    18721 acgcccacac cacccggtcc gccgtcagca cctcgccgtc cgcgacgacc cctgttttcc
    18781 gcgcgtacgg cacggcccgg gcacggacct gccggacacc gttggcgacg gccaggcgcg
    18841 cggtcacctg tgtcgcccgc cgggcccgca gcagtccggc gttcggctcc cacagcacga
    18901 aggcgaggtc gtcgacccgc aggccgggga accgccgtgc cgcctcgtca ggatcgagca
    18961 gctcgcgagg gatgtccagc cgctccagaa ccccggcgct gcgcatctcc cagccgtcag
    19021 ggtcacgggc gaaccacatc agccccgact cgacgtacag gtcctcgccg gtcctgtcct
    19081 ccagtcgccg ccaggcgtcg cgggcctgcc aggccagccg ggggtaccag tcgtccgagc
    19141 cgtgcgcaca gcgcagcagg cgggtctccc cggcgctggc ctgacgcacg tgcccgggcg
    19201 cgtactgctc gacgagcgtc acccgccagc cctcgtcggc cagccgcagc gccagcgacg
    19261 ccccccagat ccccgccccc acgacgatcg ccgatttcat ccaccactcc ttgatcgcgg
    19321 gccgaacctc cgacgtaggc tacgtcggat gcgggtttcg cctacaggcg caccggggcg
    19381 gcgataatcg gtacatgatg gcggccgaat cggcgcagac gctcgaacgt ggcttacggc
    19441 tgttgcggct gctcgccgac gcgaaccggg gccgcacgcc gaccgagctc gcccacgagc
    19501 tgggcctgag ccggccgatc gtctaccggc tcctgacgac cctgcaggcc gagggcttcg
    19561 cccggcggga cgcgcagggc cgcgtgcatc tcggtttcgg ggtgctcgtg ctggcccagg
    19621 ccgtgcatcc cctgctgcgg gcggcggcgc tgccggcgtt gcgcgcgctc gcggagcagg
    19681 cgggggcgac cgcgcacctg accgttgccg agggcgacga ggggctggcc gtcgcggtgg
    19741 tggagccgtc ctggaccgac ctccacgtcg cctaccgcga gggctcgcgt catccgctga
    19801 cgcgcggcgc ggccgggctg gcgctgctcg cgctgcgcga cggccgtacg aatccggcgg
    19861 tgcacacgag cagggggcac ctccaggagg gcgcgcaggg catcgccgcg ccggttccgg
    19921 ggccgccgtg gctggaggcg tccgtcggcg tggtcagctt cgccgacctc gacgcggaca
    19981 aggtgggccc gctggtcctg gaggccgccg gccggctcgc gaccgccctg tccgagcccc
    20041 cggactgacg gtcaccactt cagcagccgc ggctcggtga acaccgtgtt gtcgacgacc
    20101 acgtcggccc gcgccagcgg atcggcctcg gcgatgtaga tgcgctcggc gggcagataa
    20161 cggtgcaggt gcagcgcctc ggcctcggat ccggcccagt cctggtcgcg ttccgccccg
    20221 cgccgcaccg aggtctccgg cgtcacctcc atccagacgc gcaggtccca atacgcgtcg
    20281 atctccgggc ggaacgcgaa caccccgtcc acgatcgtga tcgcgccggg cgcggcggtc
    20341 gtccgcacgg acgagtggtc cacctgggtg agcgggtcga tggagcacag cgcgacgtca
    20401 cccgagccgc ccggccccgc cggttcgagc agcagggcga tcgccgcgtc gtagtcgtag
    20461 gcgttccggt agtacccctc gcccgactcc cggtcgtaca ggtgccggtc acgccacggc
    20521 cgcttgaagt cgtcgaggct cgcccgcagc acggggcgcc ccgctcgggc gaggtgctcg
    20581 gcgagctcgt ggccgaagct cgtcttcccg gccgccgtga gcccgtccac accgacgcgc
    20641 agacggcccg tcccgagagc cagcacgcgc tccgccaccc gccggaccaa tgccgtacgc
    20701 gcgggggacc cgggcgccgg cgtcggctgc cgccaggtcg agacggacag gtggatctcc
    20761 gctgtactca tgacgcacag cttgacattc ccggcggcat ggcgaatcgt cgtacatata
    20821 taggacgccg gcgtccgctt aacggacaag cagggaggtg tcatgccgca ctaccgcata
    20881 gtcggggagg tgccgcgcaa gcgccacgtg cagttccgcg ctcccgacgg cgggctgtac
    20941 aaggaggagc tcatgggaga ggagggcttc tcctccgact cctcgctgct ctaccaccgc
    21001 cacgcgccca cggccatcgt caaggccgag gccgtggacg cgggggcctc cgggctcacg
    21061 cccaacctgc cgctgtcccc gcgccatttc cgcacccagg acctgaggcc ggagggcgac
    21121 ctcgtctccg ggcggatgct gctcgcgggc aactccgacg tccgcatctc gtacgccgcg
    21181 acggacgcgc ccagcgagct gtaccgcgac tccatgggtg acgagtgcgt ctacgtcgcg
    21241 agcggccggg cccgcttcga gtcggcgtac ggcgcgctgg acgtggccga gggcgactac
    21301 gtcgtgatcc cgaccgggac gatccaccga tgggtgcccg agggcccggt gaccgcgctg
    21361 gtggtcgagg cggccgggca catcaggccg ccgaagcgct acctgtccca gtacggccag
    21421 ttcctggagc acgcgccgta cagcgagcgg gacctgcgcg cgccggccga gccgctgctc
    21481 gcggacggcg cggaggttcc ggtcctggtc aggacgcggg gcgggctgac ccggctgacc
    21541 tacgcccacc acccgttcga cgtcgtgggc tgggacggct gcctctaccc ctacgcgttc
    21601 aacatccagg acttcgagcc gatcgtgaag cgcacccacg cgccgccgcc ggttcaccag
    21661 acgttcgagg gcccgggctt cgtcatctgc tcgttctgcc cccggccgct ggacttccac
    21721 ccggaggccg tgccgatccc gtacaaccac cacaacgtgg actccgacga gttcatgttc
    21781 tacgtgggcg gggactacac ggccaggaag gggtcgggca tcgacgtcgg ctcgatctcg
    21841 cttcacccgg ccggtttcac gcacggcccg cagccgggcg cggtggaggc cgccgtcgag
    21901 gccgtgcgga agggccacac cgagacgacc gagatggccg tcatgctcga cacgttccgc
    21961 ccgctcgatc tcggtccggc cgccctcgcg tgcgaggaca ccgactacgc gtggacgtgg
    22021 gcgagatgag cttcgggctc ggcaacctgc cgtacggcgt gttctcccgg cccggggaac
    22081 cgcgcagggt cggcgtgcgg gtcggggacc acgtcctcga cctggcggcc gccctcggcg
    22141 gggacgtcta cgcggcgccc agcctcaacc cgctgctggc cctgggccgt gcggcctggc
    22201 aggagtcgcg ggcgcgggcc cgcgaggcgg cggccacggg cgaccatatg gtcccgctgg
    22261 cggaggtgac cctgcacctg ccggtcgagg tggccgatta tgtggacttc tacgcctcgc
    22321 tggagcacgc gtcgaacctc gggcggatct tccgtccgga cgacgagccg ctgaagccca
    22381 actggcggca cctgcccgtc ggctaccacg ggcgggcggg caccgtcgtc gtctcgggga
    22441 cgccggtcag gcggccgtgc gggcagcggc cgtcgtt
//
