LOCUS       NZ_JABBXA010000005     22061 bp    DNA     linear   CON 07-NOV-2024
DEFINITION  Microbispora sp. H13382 NODE_5, whole genome shotgun sequence.
ACCESSION   NZ_JABBXA010000005
VERSION     NZ_JABBXA010000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora sp. H13382
  ORGANISM  Microbispora sp. H13382
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 487215)
  AUTHORS   Liu,C.
  TITLE     Selective isolation, identification and anti-microbial activity
            study of Microbispora
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 487215)
  AUTHORS   Liu,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-APR-2020) Microbiological Resources Collection Center,
            Sichuan Industrial Institute of Antibiotics, 168 Huaguan Road,
            Chengdu, Sichuan 610052, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014161445.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 07:22:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,982
            CDSs (total)                      :: 7,906
            Genes (coding)                    :: 7,786
            CDSs (with protein)               :: 7,786
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 21 of 121
            Pseudo Genes (incomplete)         :: 104 of 121
            Pseudo Genes (internal stop)      :: 8 of 121
            Pseudo Genes (multiple problems)  :: 11 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:45:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 261980
            Orig. end                         :: 284041
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABBXA010000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22061
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22061
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22061
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12061](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12061)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(513..1490)
                     /locus_tag="HHX41_RS13105"
     CDS             complement(513..1490)
                     /NRPS_PKS="Domain: PKS_ER (23-322). E-value: 1.1e-45.
                     Score: 148.1. Matches aSDomain:
                     nrpspksdomains_HHX41_RS13105_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017569836.1"
                     /locus_tag="HHX41_RS13105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_182906160.1"
                     /sec_met_domain="ADH_N (E-value: 2.9e-07, bitscore: 25.1,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.6e-16, bitscore:
                     53.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDRMMRAVLFDRYGGPEVLYVGRVPRPEPAPGEVLVRVRAFSVN
                     GGETAARSGSLRLLTGRRFPQRAGLDFTGEVAALGAGTTDVAVGDRVWGIVGRTGFGSA
                     AEYVTVRAERLGRVPDELDLVEAAALPVATTAITALRDKAKLRPGERLLVRGAAGGVGN
                     AAVQLGRAYGAEVTALARAANLDFVRTLGADHAIDHRAIDHRTVSPEELGPFDVVLDTA
                     GTDLRAFRRLLSPGGRMVTIAFDLTRLAASLGYIAASAVHGRGRVRFFSGNPKRALFDD
                     LAREVAEGRLRPAVDTCFPLEETAAAHRALEAGGVRGKYVVRVD"
     aSDomain        complement(525..1421)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHX41_RS13105_PKS_ER.1"
                     /evalue="1.10E-45"
                     /label="HHX41_RS13105_PKS_ER.1"
                     /locus_tag="HHX41_RS13105"
                     /protein_end="322"
                     /protein_start="23"
                     /score="148.1"
                     /tool="antismash"
                     /translation="RVPRPEPAPGEVLVRVRAFSVNGGETAARSGSLRLLTGRRFPQRA
                     GLDFTGEVAALGAGTTDVAVGDRVWGIVGRTGFGSAAEYVTVRAERLGRVPDELDLVEA
                     AALPVATTAITALRDKAKLRPGERLLVRGAAGGVGNAAVQLGRAYGAEVTALARAANLD
                     FVRTLGADHAIDHRAIDHRTVSPEELGPFDVVLDTAGTDLRAFRRLLSPGGRMVTIAFD
                     LTRLAASLGYIAASAVHGRGRVRFFSGNPKRALFDDLAREVAEGRLRPAVDTCFPLEET
                     AAAHRALEAGGVRGKYVV"
     CDS_motif       complement(987..1046)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHX41_RS13105_0002"
                     /evalue="4.00E-06"
                     /label="PKSI-ER_m5"
                     /locus_tag="HHX41_RS13105"
                     /protein_end="168"
                     /protein_start="148"
                     /score="19.3"
                     /tool="antismash"
                     /translation="GERLLVRGAAGGVGNAAVQL"
     CDS_motif       complement(1080..1121)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHX41_RS13105_0001"
                     /evalue="5.60E+01"
                     /label="PKSI-ER_m5"
                     /locus_tag="HHX41_RS13105"
                     /protein_end="137"
                     /protein_start="123"
                     /score="-3.0"
                     /tool="antismash"
                     /translation="LVEAAALPVATTAI"
     gene            1593..2270
                     /locus_tag="HHX41_RS13110"
     CDS             1593..2270
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017569835.1"
                     /locus_tag="HHX41_RS13110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_182906161.1"
                     /transl_table=11
                     /translation="MEESSRIADPGLRADARRNLGRILVAARAVFAEHGIDAPMATVAR
                     RAGVGVATLYRRFPTRDALVRAAFAQQMETCARALTEALADPDPWRGFQRLFETICELQ
                     RQEQGFPAAFVAAFPDSTAEHAQARERAERDLTILVRRAKAAGALRADFHPSDLAVAVL
                     SHCGLVAALPHDSAASRRLVAYLLQSFRAEAAHGALPPPSALSLRGFPIAADGSQRQRP
                     SRA"
     gene            complement(2301..2867)
                     /locus_tag="HHX41_RS13115"
     CDS             complement(2301..2867)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX41_RS13115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_182906162.1"
                     /transl_table=11
                     /translation="MARHDGPCGGNRRGRLAGRSMLLGAVVAAAIGLSPAAAHADTWRT
                     ATSTAWGQTQSTASAAAQANARSALNSLAAQLGEVCTNVTSSASLQYTVPSGGGYVYGG
                     TATGLCAPASPGPSYTVPRSATARGEGSTSTAATQNGAAAARAAILAAGADCSGYQTTG
                     VTNVYTTPTGSWYIYDVTVSGLCVQ"
     gene            complement(3077..4705)
                     /locus_tag="HHX41_RS13120"
     CDS             complement(3077..4705)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX41_RS13120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_182906163.1"
                     /transl_table=11
                     /translation="MTRDAESGRDGVSGNVFHGPAPFQLGDRNVQINHIHHPAPQRRPL
                     VLAGAAVTTREELAAAIRLDWAAARRQFFEGAGTPGTPSDGWLGLRSWLHELDGLTADD
                     LTAQIELVDHRLRDDGLPADLKLLHLLGWLDPQGEAVWRGTVVTPQSLSEACRIGRLGE
                     SGPEWELYRDLCDGGLLEALAGFTGLSALRGTQRAWDEAWHSWRRLAARVPGLPPEARE
                     WAESGARGLLLAALLPYPESRTWLRAGCERVTPPPTGEIGWYDWLRARDGGSDTPVGWL
                     VRADFTAFAAVQAEQQRHQAAVDRQNQRISTALDAASTLRDRQWADYERRRLSPTARSG
                     AAVRAALWLGAWGAATIPVPWIMWGWARPDIAATVSWYVVALTLAAYAGRLPRVVQLGA
                     AYQPPLRRVRAWAEEARTDRASVRRGLIRAGSAAGAVLILGVLVHDIGPVATTVLLVPL
                     LAAAFYFARIGALHDWADEHRERLRDYQSRRAGSGGLPQNIARDVRSPSARLRADAYHA
                     YIRQFTGLDHSGKDEDRDNGRRDRT"
     gene            complement(4702..5133)
                     /locus_tag="HHX41_RS13125"
     CDS             complement(4702..5133)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX41_RS13125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_182906164.1"
                     /transl_table=11
                     /translation="MLVEWLAAVAAAGGTAVVQAAGTDVWVTVRQRVAHVLGRDDPERE
                     QAELMRLDQTATDLASLAPEESALIRARQEASWTARFEMLLESLGEAERERVARELNDI
                     ADQARQASVGGVSANVFNGPTAFQVGNDNRQDNHFGPRA"
     misc_feature    5142..5158
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.03"
                     /tool="antismash"
     gene            complement(5231..5938)
                     /locus_tag="HHX41_RS13130"
     CDS             complement(5231..5938)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.5"
                     /locus_tag="HHX41_RS13130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_220504009.1"
                     /transl_table=11
                     /translation="MTDAEGVPVMSYLEGVRDGLPWAYAVEDIGPDAAAVIMSRLGGWA
                     LSAPVELGRDLVERGARLQRHAFVMRCDLPIARPVEGAAPDGFQITPCDRAPADIFPAW
                     FAAYPPGHPDHRPRDAEKALREELVPLLNGEEIGPLLPCSVLAVRDGSPGEVVGGVFVN
                     DSNRGPGIADVFRHPERSPRGLGALMLSTALVRAAADGLTTIGLAVTEGNPARRLYERL
                     GFQVVDESMTVLI"
     misc_feature    complement(5801..5803)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6033..6048
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.36"
                     /tool="antismash"
     misc_feature    6090..6105
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.48"
                     /tool="antismash"
     gene            complement(6102..7595)
                     /locus_tag="HHX41_RS13135"
     CDS             complement(6102..7595)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017585947.1"
                     /locus_tag="HHX41_RS13135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_182906166.1"
                     /transl_table=11
                     /translation="MPQTHLVAGRREWIGLAVLTLPALLASLELTVTNLALPAIGTGLM
                     ASSTQLLWIADVYAFLLSGALITMGALGDRLGRRRVLLIGAAAYGVAAVLAAYAPSAGS
                     LIAARALMGVAGSTLMPSTLSLTTSMFTNPRQRTVAIGIVVSAVSAGTAIGPLVGGWLL
                     ERFWWGSAFLLAVPVMTALLVVAPFTLPEHRDAGTGRLDWLSAVLSLAAVLPVVYGLKQ
                     IAADGVEPMSLIAIAAGIAVAGAFTRRQRRLANPLVDLRLFTDRTFAVAAATLALGIFV
                     LWGSNYAVAQYLQLVYGKSPLEAGLWTSPAALGVIAGSTLAPRIARRTGSAIVIGTGLA
                     ISAAGYLILSQVSGNLAVLVAGAVVVSAGLGPMMALATDLVVSSAPPERAGAAAAISST
                     APQVGGALGIAVLGSLITAIYRADMSSAPETVRDSLTAAVAANLPSLLERARAAFVHGF
                     HLAAVVSAVLMAALAGLVVSLLRPARRIDQESTPDARTR"
     gene            7650..8123
                     /gene="soxR"
                     /locus_tag="HHX41_RS13140"
     CDS             7650..8123
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="soxR"
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017617730.1"
                     /locus_tag="HHX41_RS13140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="redox-sensitive transcriptional activator SoxR"
                     /protein_id="WP_182906167.1"
                     /transl_table=11
                     /translation="MTIAKELTVGQLSARSGVAVTALHFYEEKGLIRSRRTPGNQRRYP
                     RDTLRRVAFIRVAQRVGIPLRMVGEALATLPEGRAPTREDWERLSSGWRAELDARIEQL
                     VKLRDDLSDCIGCGCLSIDRCVLRNPDDRLGADGSGPRRLLVREAEAGSPRRR"
     gene            complement(8322..9161)
                     /locus_tag="HHX41_RS13145"
     CDS             complement(8322..9161)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017543344.1"
                     /locus_tag="HHX41_RS13145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_182906168.1"
                     /transl_table=11
                     /translation="MIIITGATGQLGRGVVERLLARVPADRIGVSVRDVSRAEDLAQRG
                     ARVRQGDFADPASLAYAFEGASQVLVVSGPADARPHRTAIEAARAAGAGRIVYTSHMGA
                     NPASPFLPMPSHAETEQDLRACGVAFTALRNGFYATTALHFVRQALETGTLAAPEDGPV
                     SWTAHADLAEAAAVALTEEGRLDGITPPLTGSESLDLADVAAIASDLTGREITRVTVPD
                     DEWVAGMVSRGVPEQQARFLLGMFEAGRQGEFAEVGPALGDLLGRKPTALRDVLANR"
     misc_feature    9147..9162
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     misc_feature    complement(9188..9205)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.3"
                     /tool="antismash"
     gene            9247..9969
                     /locus_tag="HHX41_RS13150"
     CDS             9247..9969
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019606772.1"
                     /locus_tag="HHX41_RS13150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_182906169.1"
                     /transl_table=11
                     /translation="MSDSESETASGRDRTRAHIVSVAARLLASGGRDALSTRAVAAAAG
                     TQAPTIYRLFGDKEGLLDAVAEYGFGSYLWDKKASPPADDPVEGLRAGWDLHVGFGLAN
                     PALFSLMYGDPAPGRQSPAAVAAFRMLGERIRAIAAAGRLKVGERLAADLVHAAGCGTV
                     FTLLAMPEERRDPRLSEVARDAAIAAITTDAPVVETPGPAAAAVALRAALPGATALTDG
                     ERHVLGEWLDRLAADRSG"
     gene            complement(10001..12061)
                     /locus_tag="HHX41_RS13155"
     CDS             complement(10001..12061)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PT_HPP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.5"
                     /locus_tag="HHX41_RS13155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_182906170.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.1e-50, bitscore:
                     166.1, seeds: 145, tool: rule-based-clusters)"
                     /sec_met_domain="PT_HPP (E-value: 4.7e-49, bitscore: 162.0,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="T1TS (E-value: 2.1e-33, bitscore: 111.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQSFPAVESDLGRVREILGLAGVPGRPDLATLTRQPPGGHGRL
                     IRPTLALLSYYLLAGADRAAGVRAVRAAAAVELLHMASLYHDDVIDDARQRRGRPSVNS
                     VWGARMAVLAGDLLVVNGSRILAELGEREALVAAEAGERACAGVIAETADRFLLSRTEE
                     AYLEVTGAKTAELLSLACRLGAMQAGRGPEEEDALARFGWHLGMAYQVRDDILDLTATA
                     GSLGKPANSDIVEGVYTLPVIRALAREPALARLLRRGLTAAEAETARRLVLSCGAVDEA
                     RQVVDVHMEAALGRLEGLGDPRSRDALAGYALSIMNTDRPAGPALVTVPAPSPASSPAP
                     AGVAGQLRERVQERLDAWLLQTGLAATPDEARHPRWSGMASAAARLWPDADAGQAETLG
                     RWMLVCYVLDDLLEDPELTDPGEVVRLRHRLTVLIRELGELGELGQLGELGQHGDARGA
                     GGAVATALAQAWAGIRATQPPSWRARALDHLAEWLEACEREACHRLSGFVPSLRDQLPL
                     RLRSAGPDLALDLFEVTYGRQIDPAVRDDPLFRRALDLGLATALTENDLRTLEQDEAIG
                     APYNLVRVLRHETGRTRQEAIDEVTRQVEDGHAQLDAMLASAPAFLRAAAGGTASGPDF
                     GLMHLIQERLPGWRGLHGTDRYSRTATGGGPDLARLRRELLLEYAKTGAAR"
     misc_feature    complement(10985..10987)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12058..12861)
                     /locus_tag="HHX41_RS13160"
     CDS             complement(12058..12861)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX41_RS13160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="ABC transporter permease"
                     /protein_id="WP_182906171.1"
                     /transl_table=11
                     /translation="MRGQWTCYATAVRMTFVEHLRNRLALVIVVVFIPVWAILIYALSL
                     EIALPFHLRAAGRTVTLPANVLNQLAGALQISALITGFMMFVTTLGSASFDRRLVRAGF
                     PRLSLIAAKLTALVVVALCVALYATGLICLTHPTAQPLLLTAALAGGALIYGGIGIALA
                     AVLTTDLAGLVLVTVICSIDLALQSPLATPAAASVVVRYLPDYGPMQWAVSSVALDTVP
                     WNAAGPAACWALVTAALGISAFAARTRVHRPLGEPASVSPVRSHP"
     gene            complement(12858..13511)
                     /locus_tag="HHX41_RS13165"
     CDS             complement(12858..13511)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017601374.1"
                     /locus_tag="HHX41_RS13165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_182906172.1"
                     /transl_table=11
                     /translation="MPSEEPVLRVRDVRKGYRGGPVLRGVDLDLPPGRVMGIVGENGAG
                     KTTLLRVLAGDLRPDGGSVRHGGRVGHCPQETVLHDAFTVEQHLRFFQVAYGLEDLRGA
                     EELMEALRFSGSRRARPATLSGGTRQKLNLVLALMHDPDVLLLDEPYQGFDWETYVRFW
                     DLAGELRARGRSVLVVSHLAYDAARLDILHRLEGGVLRVADRAADRVADRTGAL"
     misc_feature    complement(12861..12863)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13515..14162)
                     /locus_tag="HHX41_RS13170"
     CDS             complement(13515..14162)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX41_RS13170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_182906173.1"
                     /transl_table=11
                     /translation="MSVSRSRTYLACGLGAAGAAVLGLALTVVPSVAEGASGGGARTRP
                     VADPSPKQPGGHTVLTCAVSTGGGQPITSDPAVGKEARTVTAKGVLTLTGCASPDGSFP
                     NIRSGTATLQGSAQASCTGVQNVTGTGIISWKDGQGQSLGSSTIRPNLDAINAYNPGDM
                     MLVGEVTDGKMKGRRIAGKAAPTSDVSQCSSKGVSSVQGSGTVAFITVDAPK"
     misc_feature    14188..14204
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.81"
                     /tool="antismash"
     misc_feature    14194..14207
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.75"
                     /tool="antismash"
     gene            14257..14592
                     /locus_tag="HHX41_RS13175"
     CDS             14257..14592
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013752.5"
                     /locus_tag="HHX41_RS13175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_220504039.1"
                     /transl_table=11
                     /translation="MDARWPAPGVRGGDRVLADKAYTSGANRAYLRRRGIKATIPSKAD
                     QDANRRAKGSKGGRPPAFDPEMYKRRHAVECGINRLKCHRAVATRYDKLAVRYEATILI
                     AAINGWL"
     gene            complement(14611..16071)
                     /locus_tag="HHX41_RS13180"
     CDS             complement(14611..16071)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013714.5"
                     /locus_tag="HHX41_RS13180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_182906174.1"
                     /transl_table=11
                     /translation="MIDRRSFLRVSALAGAGAFAGTAFAPAGPRPADWSALGRGLDGKL
                     IRPGDTSYDNARRVFNSAFDSVRPAGVAYCRTAADVSECLAFARRYGVPVTSRSGGHSY
                     AGWSTGSGLVIDVSPMSGVSYSGGHATVGAGARLVDVYAKLAAHGVSIPAGSCPTVGVA
                     GLTLGGGIGVVSRQYGLTCDVLESLKVVTADGKVLTCSPGSHPDLYWASRGGGGGNFGV
                     ATSFTFRTHPTRPVTLFFLHWPWAKAAAVLKAWQAWAPAAPDAMWSNCHLGHDPSPDVM
                     VGGLYIGGKAACENLLQKLVDRVGSGPSNRYVAVSAYDHAMMVEAGCASMSVAQCHRPG
                     TLPGQNPSGRLVRDSFSAKSHFAYTPLSSAGIKALLAQVSAPGRHTVMLDAMGGAIGRV
                     RPDATAFPHRKALFSVQYFAHFGGAAAWARAAHAAMRPHFGDHAYVNYVDPELKNWRQQ
                     YYGANAARLAQVKAAYDPGRLFRLPQGV"
     misc_feature    complement(16132..16142)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            complement(16265..16453)
                     /locus_tag="HHX41_RS42280"
     CDS             complement(16265..16453)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022059.5"
                     /locus_tag="HHX41_RS42280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADH-ubiquinone oxidoreductase-F iron-sulfur
                     binding region domain-containing protein"
                     /protein_id="WP_396794461.1"
                     /transl_table=11
                     /translation="MVLGEDTCPLGETARVAGHLAARSAGQCGPCRLGLPGLARACRQM
                     QDGDPTAPTWSAWRPPP"
     gene            complement(<16509..17003)
                     /locus_tag="HHX41_RS42285"
                     /pseudo=""
     CDS             complement(<16509..17003)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013662.5"
                     /locus_tag="HHX41_RS42285"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="NADH-quinone oxidoreductase subunit I"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVRPFTLKRAEEVDLRGRGRSAFPFARKLRAVASRARDSETVVLV
                     NAAEGEPASLKDKTLLTRAPHLVLEGALLTASALGSRNVLIAVGAGELAEASVTAAVAE
                     RGLTDRSSPWVAGIQERFVSGEGGALVRAVNREARLPPGRKVRSSDSGVRGLPTLLSNT
                     ET"
     misc_feature    complement(16983..16985)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17002..17370
                     /locus_tag="HHX41_RS13190"
     CDS             17002..17370
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024953.5"
                     /locus_tag="HHX41_RS13190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DoxX family protein"
                     /protein_id="WP_138205371.1"
                     /transl_table=11
                     /translation="MSFAASTLSALVALVFLLAGAQKVLLRDPVTANLLRLGVGSTMTR
                     SIGTLEIAGALGLAAGLWFKPLAVAAAAGLTLLLIGAVGFHLRARDFAHRRHRSHAVAP
                     VVLAVVTGTTMALLLATS"
     misc_feature    complement(17033..17048)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     misc_feature    17077..17079
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17464..19704)
                     /locus_tag="HHX41_RS13195"
     CDS             complement(17464..19704)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547027.1"
                     /locus_tag="HHX41_RS13195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional polysaccharide
                     deacetylase/glycosyltransferase family 2 protein"
                     /protein_id="WP_310741963.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.1e-30,
                     bitscore: 100.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRQRRPAQSRPVQRRPPEPRGHWFLVAIAALLMSGALLLNAYAH
                     NVVGETRPPPADYGDSAELERIRSGGPLVNVSESRPLSARPKPRTVALTFDDGPDPRWT
                     PRLLDLLREHHAKATFFVLGAHVAEHPELARRLVAEGHEIGNHTYTHADLGAVPAWRAR
                     VEMSLTQKTLAAAAGIHTRLARMPYSSAPGAVGYGQLAAMRLLGDEGYLVTFTDVDTGD
                     WSRPPVDEMVLASLARTVEGEGAVIMFHDSGGDRTRTLAAVDRLLTRLEKKGYTATTLT
                     DAVGLPTAHTAAAPGERVLGTVLSFAQRASFALVEALGWFLAAAGALTLLRSALFAALA
                     WAHARRTRGRPPNTGVPPWAVPPPVSVIVPAYNEEVGIEATVRSLVRTDYPGRVEVVVV
                     DDGSTDGTGPIAASLGLPGVRVIRQPNAGKPAALTTGIAHAAHDVLVMVDGDTVFEPPT
                     IGHLVRPLADRTVGAVSGNTKVGNRRGLIGRWQHIEYVVGFNLDRRAFDLLGCMATVPG
                     AIGAFRREAVASAGGVSADTLAEDTDLTMAICRRGWRVVYEERARAWTEAPASLSQLWR
                     QRYRWCYGTLQAIWKHRGAIVERRPFGRRCLGYLALFQVILPLLAPVVDVMAMYGLLVG
                     DPLPVVAVWAGFVALQALTGWYALRLDGERASVLWALPLQQFVYRQLMYLVVIQSVATA
                     VLGARLRWHTVRREGTFALAGQAVAIPAAGRPAGRRRRAVRGANAPRRRSRP"
     gene            complement(19701..20282)
                     /locus_tag="HHX41_RS13200"
     CDS             complement(19701..20282)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX41_RS13200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_182906175.1"
                     /transl_table=11
                     /translation="MEDHHPARTAVFVDHSGRRAKILTAAAVGGAIVVLALTLTLVSGA
                     LTGPELPPMGWVGTRGQQVVERSPTGSPTASPSSGHRSEHRRVPRASGTPHSTAAARRA
                     TSGRGLPSRVPSASPSPRGSLKPSTTPPAGREPDVEISSSGQSAPAPSSEPEVPPATAP
                     SGELTRTPAPGPSAVQTPPGQPGQTPGTTQ"
     misc_feature    20303..20318
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.0"
                     /tool="antismash"
     misc_feature    complement(20512..20528)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            20571..21392
                     /locus_tag="HHX41_RS13205"
     CDS             20571..21392
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015272.5"
                     /locus_tag="HHX41_RS13205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tryptophan 2,3-dioxygenase"
                     /protein_id="WP_169982910.1"
                     /transl_table=11
                     /translation="MPATPYGRAGSGDVLPPPRSFGEEGGRLSYGGYLRLPELLAQQEQ
                     RSGASDELLFITVHQVYELWFKLLLHELERIRDAMVEGALWRARHLFRRVHAVEKVMVD
                     QVQVLETMTPQDFLEFRSVLAPASGFQSVQFRELEFLSGAKDPSYLGRLRDADDAEIAR
                     LRRRLAEPSLWDAYLIALSQRGLPVSDEEIMESLLAVARDRGSYDDLWDLAEDLLTHDE
                     TTALWRMRHVQMVERQIGTKSGTGGSSGAPYLRGRTRLHFFPLLWELRAWL"
ORIGIN
        1 gacggcctcg cggagggtcg gtccgggcac gtactcggtg accagataga cggtctcgcc
       61 gtccacctcc gcgtccagca cggcggcggt gcagaaacgg gcgacccgct tggccgcctc
      121 cacttcgcgc cggaaccggc ggcggaagcc ggggtcggcg gcgatcgtgt ggtggagcag
      181 cttgaccgcc acgtgcgtgc cgtccggcgc ctcacccagg tagacggtgc ccatcccgcc
      241 ctcgcccagc ctgcgcagca gccggtaagg ccccacctgg gccgggtcac ccgcccgcag
      301 gcccgactcg tgctgccccg gtaagccccc cggctcgccg ccgccgttca catcgccccc
      361 gctgggatgt ccggaaggtc aggtcactaa ggatcttatt gacggccgcc gggcgcggcc
      421 atggccggac acgtgccatc acggtgaggc cgtgaggggg agcgaagcgg cgtcggccct
      481 cccgccccgg gcgtccgggc cgcgaaccgc cttcaatcga ccctgacgac gtatttgccc
      541 cgcaccccgc ccgcctccag cgcccggtgt gccgccgccg tctcctccaa cgggaagcac
      601 gtgtccaccg cggggcgcag tctcccctcc gccacctcac gggcgaggtc gtcgaagagt
      661 gcccgcttgg ggttgccgct gaagaagcgc acccggccgc gtccgtgtac ggcgctggcg
      721 gcgatgtagc cgagtgacgc ggcgagccgt gtcaggtcga aggcgatggt gaccatgcga
      781 ccgccgggcg acagcaggcg ccggaaggcc cgcaggtcgg tgcccgcggt gtcgaggacc
      841 acgtcgaacg ggcccagttc ttccggcgag acggtccggt ggtcgatggc gcggtggtcg
      901 atggcgtggt cggcgccgag cgtacggacg aagtcgaggt tggcggcgcg ggccagggcc
      961 gtgacctcgg cgccgtaggc ccgtccgagc tggacggcgg cgttgccgac gccgcccgcg
     1021 gcgccgcgta cgagcagccg ttcgccgggg cgcagtttgg ccttgtcgcg cagcgccgtg
     1081 atggccgtgg tcgccaccgg cagcgcggcg gcttccacca ggtccagctc gtccgggacc
     1141 cggccgagcc gctcggcccg gaccgtcaca tactcggcgg cgctgccgaa tccggtgcgg
     1201 cccacgatgc cccacacccg gtcgccgacc gcgacgtccg tcgtgccggc gccgagcgcg
     1261 gcgacctcgc cggtgaagtc caacccggcg cgttgcggga acctccgtcc ggtgaggaga
     1321 cggaggctgc cggaacgggc cgccgtttcg ccgccgttga cgctgaacgc gcgcacccgc
     1381 acgagcacct ccccgggcgc cggttcaggg cgcggcaccc ggcccacgta cagcacctcg
     1441 gggccgccgt agcggtcgaa aagcactgct ctcatcatgc ggtcgtccat cgttctcacc
     1501 ttcgccacca gtggacgtgc gggggatctg gcccgagcgt aggctcataa gtggacgccg
     1561 ccgtccgttt ggaccggaag tgagagacag tggtggagga atcctctcgg atcgccgacc
     1621 cggggctgcg ggccgacgcc cggcgcaacc tggggcgcat cctcgtcgcc gcccgtgcgg
     1681 tcttcgccga gcacgggatc gacgcgccca tggcgaccgt ggcccggcgg gccggggtcg
     1741 gtgtggcgac gctgtaccgg cgtttcccga cccgggacgc cctggtgcgg gccgcgttcg
     1801 cgcagcagat ggagacctgc gcccgagcgc tgaccgaggc actggccgac cccgacccct
     1861 ggcggggctt ccagcggctg ttcgagacga tctgcgagct tcagcggcag gaacagggct
     1921 tcccggccgc gttcgtcgcg gccttcccgg acagcacggc ggagcacgcg caggcccggg
     1981 aacgggctga gcgggacctc acgatcctgg tccgcagagc caaggcagcg ggcgcgctgc
     2041 gggccgattt ccacccgtcc gacctcgccg tggccgtgtt gtcccactgc ggtctggtcg
     2101 ccgcgctgcc gcatgacagc gccgcgtccc ggcgcctggt ggcatacctg ctccagtcgt
     2161 tccgcgccga ggcggctcac ggggccctgc cgccgccgag cgccctgtcg ctgcgcggtt
     2221 tcccgatcgc ggccgacggc tcccagagac agcgcccctc cagggcctga ggcgagagcg
     2281 ggcgacgccc ggtggtggcg ctactgcacg cagagcccgg acaccgtgac gtcgtagatg
     2341 taccagctcc cggtcggagt cgtgtacacg ttggtcacgc cggtcgtctg gtagccgctg
     2401 cagtcggcgc cggccgcgag gatggcggcc cgggccgctg ccgcgccgtt ctgcgtggcc
     2461 gccgtcgacg tgctgccctc accgcgcgcc gtcgcgctgc gcggcaccgt gtaggagggt
     2521 cccggcgacg ccggcgcgca cagaccggtc gccgtcccgc cgtacacgta gccgcctccg
     2581 ctgggcacgg tgtactgaag gctcgccgac gaggtcacgt tcgtgcagac ctcccccagc
     2641 tgagcggcca ggctgttgag agcgctacgg gcgttcgcct gggccgccgc cgacgccgtg
     2701 gactgggtct ggccccacgc cgtggaggtc gccgtccgcc aggtgtcggc gtgggccgct
     2761 gccgggctga ggccgatcgc cgccgcgacg accgctccca ggagcatcga ccggccggcg
     2821 agccgtccgc gccggttccc gccgcacggt ccatcgtgcc gggccattcg cgtctccctt
     2881 gatcagcgcc ttgtgcatcg accgtgcagg atgtgatctg atccccgctt atgcgcatga
     2941 tctcggggcg tgaagtcatc gtaggttcgc cgtttcccgg cggccatcct cggccgcgtg
     3001 ggcggcacgg acatgctggt gggcgatcac ggccgatgta agtttcggcg ccctcgcccc
     3061 gagcccttcc tgcccgtcag gtccggtcgc gacggccgtt gtcgcggtcc tcgtccttcc
     3121 cgctgtggtc gaggccggtg aactgacgga tgtacgcgtg ataggcgtcg gcccgaagcc
     3181 tggccgacgg cgatcgaaca tcccgggcga tgttctgggg gaggccgccg gaaccggccc
     3241 gcctggactg gtagtcccgc agtcgttccc gatgctcgtc cgcccagtcg tgcagcgccc
     3301 cgatgcgggc gaagtagaac gccgccgcga gcaggggcac gaggagaacc gtcgtcgcga
     3361 cagggccgat gtcgtgcacg agcaccccga ggatcaggac ggccccggcc gcgctgccgg
     3421 ctctgatcag acccctccgg acgctcgcgc ggtcggtccg ggcctcctcg gcccacgcgc
     3481 gcacgcgccg cagcggaggc tggtaggccg cgcccagctg tacgactcgc ggtagccggc
     3541 ccgcgtacgc cgccagggtc agcgcgacga cataccagga caccgtcgcg gcgatgtccg
     3601 gacgcgccca gccccacatg atccagggca ccgggatcgt ggccgcgccc caggccccga
     3661 gccacagcgc cgcgcggacg gccgctcccg atcgggcggt gggcgagagc cggcggcgct
     3721 cgtagtcggc ccactgccgg tcgcgcaggg tggaggcggc gtccagcgcg gtcgatatcc
     3781 gctggttctg ccggtcgacc gccgcctggt gacgctgctg ttccgcctgc accgcggcga
     3841 aagcggtgaa gtcggcgcgc acgagccatc cgacaggggt gtccgagccg ccgtcccgcg
     3901 cgcgcaacca gtcgtaccag ccgatctcac cagtgggggg aggcgtcacg cgctcgcagc
     3961 cggcgcgcaa ccacgttctg ctctccgggt agggcagaag agccgccagc agcagcccgc
     4021 gcgccccgct ctcggcccat tcccgggctt ccggcggcag tccgggaacc cgagccgcca
     4081 accgccgcca cgaatgccag gcctcgtccc atgcccgctg cgttccccgc agcgcgctca
     4141 ggccggtgaa cccggccagg gcttccaaca agccgccatc gcagaggtcg cggtagagct
     4201 cccattccgg gccgctttcc cccagacgac cgatcctgca tgcctcggag agcgactgcg
     4261 gggttacgac cgttcctcgc cagacggctt cgccctgcgg atcgagccag cccagcaggt
     4321 gaagcagttt gaggtcggcc gggagtccgt cgtcgcggag ccgatggtcg acgagttcga
     4381 tctgggcggt caggtcgtcg gcggtgagac cgtcgagctc gtgcagccag gagcgaagtc
     4441 cgagccaccc gtcggagggg gtgcctggcg tgcccgcgcc ctcgaagaac tgacgcctcg
     4501 cggcagccca gtcgaggcgg atggcggcgg ccagttcctc ccgggtcgtg accgccgcac
     4561 ctgcgaggac cagcggccgg cgctgcggcg ccggatggtg gatgtgattg atctggacgt
     4621 tgcgatcgcc gagttggaaa ggggccgggc cgtggaagac gtttcccgat actccgtccc
     4681 ttcccgattc ggcgtcgcgg gtcatgccct cggcccgaag tggttgtctt gacggttgtc
     4741 gttgccgacc tggaatgcgg tcggtccgtt gaagacgttc gccgacactc cccccaccga
     4801 tgcctgacga gcctggtcgg cgatgtcgtt cagctcgcgg gcgacccgtt cgcgttcggc
     4861 ctcgccgaga ctctccagca gcatctcgaa tcgggccgtc caggacgcct cctgccgtgc
     4921 ccgtatcagc gccgattcct ccggggcgag cgaggcgagg tccgtcgcgg tctgatccag
     4981 ccgcatcagt tccgcctgct cacgttcggg atcgtcgcgg ccgagcacgt gcgccacccg
     5041 ctgccgcaca gtcacccaca cgtccgtgcc cgcggcctgc accacggcgg ttccgcccgc
     5101 cgcggccacc gctgccagcc attcgacgag cattcccggc ctccttacaa gatctgatga
     5161 cactgtatat ctggccttga cgaggtcgcc ggatgtctgg aaatcgaccg gtgaagcgag
     5221 gccgcctgat tcagatcagg accgtcatgg actcgtcgac cacctgaaag ccgagcctct
     5281 cgtagaggcg acgggcgggg ttgccctcgg tgaccgccag gccgatcgtg gtcagcccgt
     5341 ccgcggctgc acggaccaag gcggtcgaca gcatgagcgc gccgaggccc cgcggcgacc
     5401 gctcggggtg ccggaacacg tccgcgatcc ccggcccccg gttggagtca ttgacgaaga
     5461 cgccgcccac cacctcgccg ggggaaccgt cgcgtacggc gagcacgctg cacggaagca
     5521 gcgggccgat ctcctcgccg ttgagcagcg gaacgagctc ctcgcgcagg gccttctcgg
     5581 cgtcccgggg ccggtggtcg ggatggccgg gcgggtaggc cgcgaaccac gcggggaaga
     5641 tgtcggcggg cgcccggtcg cagggcgtga tctggaagcc gtcgggagcg gcgccctcga
     5701 cgggccgggc gatcggcaga tcacaccgca tcacaaaggc gtgccgctgc aggcgggcgc
     5761 ctcgctccac caggtcccgg ccgagctcga ccggcgcgga taaggcccag cccccgagcc
     5821 gtgacatgat cacggcagcg gcgtccgggc cgatgtcctc gaccgcgtag gcccagggaa
     5881 ggccgtcacg gacgccttcc aggtaactca tcaccgggac gccctcagcg tcggtcaacc
     5941 tccgccgctc ctcgctcata cgccgaaggg tcgcgcagtc gcggcccggc aggcaaccat
     6001 cgcgccccga gattgccgag aggcgctatt gcacgcagag agcggacacc gtcacgtcgt
     6061 agatgtacca gcttccggtc ggagtcatgt agacgcttcc ttcaccgggt tcgtgcatcc
     6121 ggcgtgcttt cctggtcgat gcgtctcgcc gggcggagca gggacacgac cagaccggcg
     6181 agggccgcca tcaggaccgc gctcaccacc gcggccaggt ggaatccgtg aacgaaggcc
     6241 gcgcgggccc tctccaggag cgaggggaga ttcgcggcca cagctgcggt caagctatct
     6301 cggacggttt ctggggccga ggacatgtcc gcacggtaaa tcgcggtgat caggctgccg
     6361 agtacggcga tgccgagcgc tccgccgacc tgcggggcgg tggaggagat cgccgccgcc
     6421 gcgccggccc gctcgggcgg ggccgaactc acgaccaggt cggtcgccag cgccatcatc
     6481 ggccccagac cggcggagac gacgacggct ccggctacga ggacggcgag attcccggac
     6541 acctggctga gaatgagata tccggcggca gatatcgcca ggcccgtgcc gatgacgatc
     6601 gcgctgccgg tcctgcgcgc gatcctcggc gccagcgtgg atccggcgat cacccccagg
     6661 gcggccggcg acgtccacag gcccgcctcc agcggtgact tgccgtacac cagttgcaga
     6721 tactgcgcga cggcgtagtt ggagccccac aggacgaaga tgccgagcgc cagtgtggcg
     6781 gccgcgaccg cgaacgtgcg gtcggtgaac agccgcaggt ccaccagggg gttggcgagg
     6841 cggcgctgtc ggcgcgtgaa cgcgccggcg accgcgatcc cggccgcgat cgcgatgagg
     6901 gacatcggct cgacgccgtc ggcggcgatc tgcttgagcc cgtagacgac cggcagcacc
     6961 gccgcgagcg acagcaccgc gctcagccag tccagccggc ccgtgccggc gtccctgtgc
     7021 tcgggaagcg tgaacggcgc cacgacgagc agcgccgtca tcacgggtac ggccaggagg
     7081 aacgccgacc cccaccagaa acgctccagc agccagccgc ccaccagcgg gccgatcgcg
     7141 gtgcccgcgg agacggccga gacgacgatg ccgatggcca ccgtccgctg tcggggattg
     7201 gtgaacatcg acgtggtcag cgacagcgtg gacggcatca gggtcgatcc ggcgacgccc
     7261 atcagcgcgc gggccgcgat caggctcccg gcgctcgggg cgtacgcggc gagaaccgcg
     7321 gccacgccgt acgcggcggc cccgatgagc agcacgcggc ggcggccgag ccggtcaccc
     7381 agagcgccca tcgtgatgag cgctccggaa aggaggaagg cgtagacgtc ggcgatccac
     7441 aacaactggg tgctgctggc catcaggccc gtgccgatgg cgggcaatgc gaggttcgtg
     7501 acggtcagtt ccagagaggc gaggagggcg ggcagtgtca ggacggccag gccgatccat
     7561 tcccgcctcc ccgcgaccag gtgcgtctgg ggcatggaac ccaggatcaa acctcgacta
     7621 tggtcgaggt caagccttag tctccggcta tgacgatcgc gaaggaactc acggtcggac
     7681 agctctccgc ccggtctggc gtcgcggtga ccgcgctgca cttctacgag gagaaggggc
     7741 tgatccgcag ccggcgcacg cccggcaacc agcgccgtta cccccgtgac acgcttcgcc
     7801 gggtcgcctt catccgtgtg gcgcaacgcg tcggcatccc gctgcgcatg gtcggcgagg
     7861 ccctggccac gcttcccgag ggacgcgcgc cgacgcgcga ggattgggag cggctgtcct
     7921 ccggctggcg ggcggagctc gacgcccgca tcgagcaact ggtcaagctc cgtgacgacc
     7981 tgtccgactg catcggctgc ggctgcctgt ccatcgaccg ctgcgtcctg cgcaaccccg
     8041 acgaccgcct cggcgcggat gggtccggcc cgcgccgact gctggtccgc gaggcggagg
     8101 ccggctcgcc aaggcggcgg tagcgttttc ggatgctcga cgcctgaccg tcagcgggcg
     8161 gcgccggttt cgactccccg atcgcgtacg cccaggggag gttgtcacgg acgccttccc
     8221 ggtagctcat gaccgggatg ccggcagcgc cggtgaggct tcgccgctcg tcgcccatac
     8281 gtcgaaggag cgcgcgcggc cggacccggc aggcaaccct tttatcggtt cgcgagcacg
     8341 tcgcggagcg cggtcggctt gcggccgagc aggtcaccga gcgccgggcc gacctcggcg
     8401 aactccccct gacggccggc ctcgaacatg cccagcagga accgggcctg ctgctcgggc
     8461 acgccgcgcg acaccatgcc cgcgacccac tcgtcatccg ggacggtgac gcgggtgatc
     8521 tcgcgacccg tcaggtcgga ggcgatcgcg gcgacgtccg cgaggtcgag cgactcggag
     8581 ccggtcagcg gcggcgtgat cccgtcgagc cggccctcct cggtcagcgc gacggcggcc
     8641 gcctcggcga ggtcggcgtg ggcggtccag gagaccgggc cgtcctcggg cgcggcgagc
     8701 gtgccggtct cgagcgcctg ccgcacgaag tggagcgcgg tggtcgcgta gaagccgttg
     8761 cgtagcgcgg tgaacgccac cccacatgcg cgcaggtcct gctccgtctc ggcgtgggac
     8821 ggcatcggga ggaaggggga ggccgggttc gcgcccatgt ggctggtgta gacgatcctc
     8881 ccggcgcccg ccgccctggc cgcctcgatc gccgtacggt gcgggcgggc gtcggccggg
     8941 ccggagacga cgagcacctg cgaggcgccc tcgaacgcgt acgccaggct cgcggggtcg
     9001 gcgaagtcgc cctgccgtac gcgggcgccg cgctgggcga ggtcctcggc tcgcgaaacg
     9061 tcgcggacgc tgacgccgat ccggtcggcg ggaacgcgcg cgagcaaccg ctcgacgacg
     9121 cctcggccga gctgaccggt cgctccggtg atgatgatca cggtctacgc cattgctatc
     9181 gctgatattg acttcacgct aacatcggaa attcagcgat aacaacttac tgctatcgtt
     9241 ggaagcatga gcgactctga gagcgagacg gcgagcggcc gcgacaggac gcgggcgcac
     9301 atcgtgtcgg tcgcggcgcg actgctcgcg agcggcgggc gcgacgccct ctcgaccagg
     9361 gcggtggccg ccgcggcggg gacgcaggca ccgacgatct accgcctgtt cggcgacaag
     9421 gagggcctgc tcgacgcggt cgccgagtac ggcttcggct catacctgtg ggacaagaag
     9481 gcgagcccgc ccgccgacga cccggtcgaa gggctgcgcg ccgggtggga cctgcacgtc
     9541 gggttcgggc tggcgaaccc cgccctgttc tcgctcatgt acggcgatcc cgcaccgggc
     9601 cggcagtcgc ccgccgccgt cgccgccttc cgcatgctgg gggagcgcat ccgcgccatc
     9661 gccgccgccg gccggttgaa ggtcggcgag cgcctggcgg cggacctcgt gcacgccgcc
     9721 ggctgcggca cggtcttcac gctgctcgcc atgcccgagg aacggcgtga cccgcgcctg
     9781 tccgaggtgg cccgcgacgc ggcgatagcc gccatcacca ccgacgcccc cgtggtcgag
     9841 acccccggac ccgccgcggc ggcggtggca ctacgcgccg cgctgcccgg cgccacggct
     9901 ctcaccgacg gtgaacgtca cgtgctcggc gaatggctcg accgcctcgc cgccgaccga
     9961 tccggctgag atctcggcgg gagcgctcga caaggcggcg tcagcgtgcc gcgccggtct
    10021 tggcgtactc cagcaggagc tcccggcgca gccgggccag gtcgggtccg cctccggtgg
    10081 ccgtacggct gtagcggtcg gtgccgtgca ggccgcgcca accgggcagc cgctcctgga
    10141 tgaggtgcat gagaccgaag tccgggccgg aggccgtgcc gcccgcggcg gcccgcagga
    10201 acgcgggggc ggaggcgagc atggcgtcga gctgggcgtg gccgtcctcg acctgccggg
    10261 tcacctcgtc gatcgcctcc tgcctggtgc ggccggtctc gtggcggagc accctgacca
    10321 ggttgtaggg ggcgccgatg gcctcgtcct gctccagggt ccgcaggtcg ttctcggtga
    10381 gcgcggtggc cagcccgagg tcaagcgccc ggcggaagag cggatcgtcg cggacggccg
    10441 ggtcgatctg cctgccgtac gtcacctcga agaggtcgag ggcgaggtcg ggcccggcgc
    10501 tgcgcaggcg cagcgggagc tggtcgcgca ggctggggac gaacccgctg agccgatggc
    10561 acgcctcgcg ctcgcacgcc tccagccatt cggcgaggtg gtccagggcg cgtgcccgcc
    10621 acgagggcgg ctgcgtcgcg cggatccccg cccaggcctg ggcgagagcg gtggcgaccg
    10681 ccccaccggc cccccgggcg tcgccatgct gaccgagttc gccaagctga ccgagttcgc
    10741 cgagttcgcc gagctcgcgg atgagaacgg tgagccggtg ccgcagccgg acgacctccc
    10801 cggggtcggt gagctcgggg tcctccagga ggtcgtcgag cacgtagcac accagcatcc
    10861 accggcccag cgtctcggcc tgcccggcgt cggcgtccgg ccacaaccgc gcggcggccg
    10921 aggccatgcc gctccaccgc ggatggcggg cctcatccgg cgtggcggcg agcccggtct
    10981 gcagtaacca ggcgtccagc cgctcctgca cccgctctcg cagctgcccg gcgacgcctg
    11041 ccggagcggg ggacgacgcg ggggacggcg cgggcacggt gacgagagcc ggaccggccg
    11101 gcctgtccgt gttcatgatc gatagcgcgt aaccggccag cgcgtcgcgt gaccgcggat
    11161 cgccgaggcc ctcaagccgg ccgagagccg cctccatgtg aacgtcgacg acctgccggg
    11221 cctcgtccac cgctccgcac gacaggacca ggcgccgggc ggtctcggcc tcggccgccg
    11281 tcaggccgcg gcgcagcagc cgggcgagcg cgggctcgcg ggccagggcc ctgatcacgg
    11341 ggagcgtgta gacgccctcc acgatgtcgg agttggccgg ctttccgagg ctcccggccg
    11401 tcgcggtcag gtcgaggatg tcgtcgcgca cctgataggc catgccaaga tgccagccga
    11461 accgcgccag cgcgtcctcc tcctcagggc cccgcccggc ctgcatggcg cccaggcggc
    11521 aggccaggga cagcagctcg gcggtcttgg cgccggtcac ctccaggtag gcctcctcgg
    11581 tgcgggagag caggaagcgg tcggccgtct cggcgatcac ccccgcgcag gcgcgttcgc
    11641 cggcctccgc ggcaaccagc gcctcgcgtt cgcccagctc cgcgaggatc cggctgccgt
    11701 tgacgaccag gaggtcaccg gccaggaccg ccatgcgcgc gccccacacg ctgttgacgc
    11761 tcggcctgcc cctgcgctgc cgtgcgtcgt cgatcacgtc gtcgtggtag agggacgcca
    11821 tgtgcagcag ctcgacggcc gccgcggcgc gtacggcgcg gacgccggcg gcccggtccg
    11881 caccggcgag caggtagtac gacagcagcg ccagagtggg ccggatcagg cggccgtggc
    11941 cgcccggcgg ctgcctggtc agcgtggcca gatccggccg gcccggcacc ccggccagac
    12001 cgaggatctc ccgcactcgt cccaggtcgg attccacggc ggggaaagac tgcgttgtca
    12061 tgggtggctc ctgacgggac tcacggacgc cggctcaccg agcggccggt ggacacgcgt
    12121 acgggcggcg aaggcggaga tgccgagggc cgccgtgacc agcgcccagc acgcggccgg
    12181 gcccgcggcg ttccagggca ccgtgtccag ggccacggac gagacggccc actgcatcgg
    12241 cccgtaatcg ggcaggtagc gcacgacgac gctggccgcg gccggagtgg cgagcgggct
    12301 ctgcagggcc aggtcgatcg agcagatcac ggtgacgagg accagaccgg ccagatcggt
    12361 ggtcagcacc gcggcgagcg cgatgccgat ccctccgtag atcagcgctc ccccggcgag
    12421 ggcggcggtg agcagcaggg gctgcgcggt cgggtgggtc aggcagatca ggccggtggc
    12481 gtagagcgcg acgcagagcg cgaccaccac cagggcggtg agcttcgccg cgatcaggga
    12541 cagccgcggg aaaccggccc gcaccagccg gcggtcgaag gacgccgagc ccagggtggt
    12601 cacgaacatc atgaacccgg tgatcagcgc cgagatctgc agcgccccgg cgagctggtt
    12661 gaggacgttg gccggcagcg tgacggtccg gccggcggcc cggaggtgga aggggagcgc
    12721 gatctccagg gacagggcgt agatgaggat cgcccacacc gggatgaaga ccacgacgat
    12781 caccagtgcc agccggttgc gcaggtgctc cacgaacgtc atgcgcacgg cggtggcgta
    12841 acaggtccac tgacccctca taaggcaccg gtcctgtccg cgaccctgtc cgcagccctg
    12901 tccgcgaccc gcagcacgcc gccctccagc cgatgaagga tgtcgaggcg cgccgcgtcg
    12961 tacgcgaggt gggagaccac cagcaccgag cggccacgcg cgcgcagttc cccggccagg
    13021 tcccagaacc gcacgtacgt ctcccagtcg aagccctggt agggctcgtc gagcaggagc
    13081 acgtccgggt cgtgcatcag ggccaggacg aggttcagct tctgccgcgt cccgccgctc
    13141 agcgtggcgg ggcgggcccg gcgggagccg gagaaccgca gcgcctccat cagctcctcg
    13201 gccccgcgca ggtcttccag gccgtaggcg acctggaaga accgcaggtg ctgctcgacc
    13261 gtgaacgcgt cgtgcagcac cgtctcctgc gggcagtgac ccacgcgccc gccgtggcgc
    13321 accgacccgc cgtccggccg caggtcgccg gcgaggacgc gcagcagcgt ggtcttgccc
    13381 gcgccgttct ccccgacgat ccccatcacc cggccgggcg gcagatcgag atccaccccg
    13441 cgcaggaccg ggccgccccg gtagcccttc cgcacgtccc gcacccgcag cacgggctct
    13501 tccgacggca tcgactactt cggcgcgtcg acggtgatga aggcgaccgt gccgctgccc
    13561 tggacgctgc tcacgccctt gctggagcac tggctgacgt ccgaggtggg agccgccttc
    13621 ccggcgatcc gcctgccctt catcttcccg tcggtgacct cgccgacgag catcatgtcg
    13681 ccggggttgt acgcgttgat cgcgtcgagg ttggggcgga tcgtggagct gcccagcgac
    13741 tggccctggc cgtccttcca gctgatgatg cccgtgccgg tgacgttctg gacgccggtg
    13801 caggacgcct gcgcgctgcc ctggagggtg gccgttcccg agcggatgtt ggggaagctg
    13861 ccgtcggggg aggcgcagcc ggtgagcgta agaacgccct tggcggtcac cgtgcgggcc
    13921 tccttgccca cggccgggtc gctggtgatc ggctggccgc cgccggtgct caccgcgcag
    13981 gtcagcacgg tgtggccgcc cggctgcttc ggcgaggggt cggcgaccgg cctggtgcgc
    14041 gcgccgccgc ccgacgcgcc ttcggccacc gacgggacga ccgtcagggc caggcccagc
    14101 acggccgctc ccgcggcgcc gagaccacag gccaggtacg tacgagatcg agaaacgctc
    14161 atggacatcc ccccgagtga ttgctgacgg taatctaact atcacaatca gcaacggcga
    14221 gggtggcgag tcaatgcgcc cgacgagcgg gcacccctgg acgcgaggtg gccggcgcca
    14281 ggcgttcgcg ggggtgatcg cgtcctggcc gacaaggcct acacctctgg ggccaaccgc
    14341 gcctacctgc ggcggcgcgg gatcaaggcc actatcccca gcaaggccga tcaggatgcc
    14401 aaccgccgcg ccaaaggctc caagggcggg cggccacccg ccttcgatcc cgagatgtac
    14461 aagcggcgcc acgctgtcga gtgcggcatc aaccggctca aatgccaccg tgctgtcgcc
    14521 accaggtacg acaaactcgc cgtccgctac gaagccacga tactgatcgc cgcgatcaac
    14581 ggatggctct gatcgacttt gatacaggcc ctacacgccc tggggaaggc ggaacaggcg
    14641 gcccgggtcg tacgccgcct tgacctgggc cagacgggcg gcgttcgcgc cgtagtactg
    14701 ctgccgccag ttcttgagct cggggtcgac gtagttcacg tacgcgtggt cgccgaagtg
    14761 gggccgcatg gcggcgtggg cggcccgagc ccaggcggcg gcgccgccga agtgcgcgaa
    14821 gtactgcacg ctgaacagag ccttgcggtg cgggaacgcg gtggcgtcgg ggcggacccg
    14881 gccgatggcg ccgcccatcg cgtcgagcat cacggtgtgc cgtcccggcg cggagacctg
    14941 ggccagcagc gccttgatcc cggcggacga cagcggggtg taggcgaagt gcgacttggc
    15001 cgagaacgag tcgcggacca gcctgccgct cgggttctgc cccgggaggg tgccgggacg
    15061 gtggcactgg gccacggaca tcgacgcgca gcccgcctcc accatcatcg cgtggtcgta
    15121 cgccgagacc gcgacgtacc ggttcgaggg gccggagccg acgcggtcga cgagcttctg
    15181 cagcaggttc tcgcacgccg ccttgccgcc gatatacagc ccgccgacca tcacgtcggg
    15241 cgacgggtcg tggccgaggt ggcagttgga ccacatcgcg tcgggcgcgg cgggcgccca
    15301 cgcctgccag gccttcagca cggccgcggc cttcgcccag ggccagtgca ggaagaacag
    15361 ggtcacggga cgcgtcggat gggtccggaa cgtgaacgac gtcgccacgc cgaagttgcc
    15421 gccaccgccg ccgcgcgagg cccagtagag gtcggggtgc gagcccggcg agcaggtcag
    15481 caccttcccg tcggccgtga cgaccttcaa cgactccagc acgtcgcagg tcaggccgta
    15541 ctgccgcgac accacgccga tgccgccgcc cagcgtgagc ccggccaccc cgaccgtcgg
    15601 gcaggagccc gccgggatgc tgacgccgtg cgcggccagc ttggcgtaca cgtcgaccag
    15661 ccgcgccccg gcgccgaccg tggcgtggcc gcccgaatac gaaacgccgc tcatcggcga
    15721 cacgtcgatt acgaggccgc tgcccgtgga ccagcccgca tagctgtggc cgcccgaccg
    15781 ggaggtcacc ggcacgccat agcgccgggc gaacgccagg cactccgaca cgtccgccgc
    15841 cgttctgcag taggccaccc cggccggccg tacggagtcg aaggccgagt tgaacacgcg
    15901 acgcgcgttg tcgtacgacg tgtcgccggg gcggatcagc ttgccgtcca gcccccggcc
    15961 gagcgcggac cagtcggcgg gacggggacc cgcgggggcg aaagccgtgc ccgcgaacgc
    16021 gccggccccg gccagcgccg agactcgaag gaaactccgt ctgtcgatca tggtcgtact
    16081 cccgaggtgg tgatctacct cgttgagacg cctgtggatc tggtctggtt ggtcacattg
    16141 ccatcactac gctcctccta tccgcagggc gagtgcgggg cacatctcca tggccttctg
    16201 cgcctcgccg ggcagccagg agggcacgcc ggtgtccatg aacaccggga ggcgccgcgg
    16261 cccttcacgg cggcggccgc caggcggacc aggtcggggc cgtcgggtcg ccgtcctgca
    16321 tttgccggca cgcccgcgcg agccccggca ggccgaggcg gcacggcccg cactgcccgg
    16381 ccgaccgtgc ggcgaggtgg cccgccaccc gcgcggtctc gccgagcggg caggtgtcct
    16441 cgccgaggac cacgatgatg cccgcgccca gctcgccgcc cctcagcgag cacggcgagc
    16501 tgggcgaagg tctcggtgtt cgacagcagc gtgggcagcc cgcgcacccc gctgtcgctg
    16561 gagcggacct tgcggcccgg gggcaggcgc gcctcgcggt tgaccgcgcg gaccagcgcg
    16621 ccgccctccc cggacacgaa ccgctcctgg atgcccgcga cccacggact ggaccggtca
    16681 gtcaggccgc gctcggccac tgcggcggtg accgaggcct cggccagctc gcctgcgccg
    16741 accgcgatca ggacattccg tgagccgagc gcgctggccg taagcagggc gccctccagc
    16801 accaggtggg gcgcccgggt gagcagggtc ttgtccttca ggctggcggg ctcgccctcg
    16861 gcggcgttca ccagcacgac ggtctcgctg tcgcgggcgc gtgaggcgac ggcgcgcagc
    16921 ttgcgcgcga acgggaacgc gctccgcccc cggccccgca ggtccacctc ctcggctctc
    16981 tttaatgtga aaggtcgcac catgtcgttt gccgccagca ccctgagcgc tctggtcgct
    17041 ctcgtcttcc tccttgccgg cgcccagaag gttctgttac gggatcccgt gacggccaac
    17101 ctgctcaggc tcggcgtagg ctcgacgatg acccgctcga tcggcaccct ggagatcgcc
    17161 ggcgcgctcg ggctcgcggc cggcctctgg ttcaagccgc tcgccgtcgc ggccgcggcc
    17221 ggtctcacgc tgctgttgat cggcgcagtg gggttccatc tccgcgcccg cgacttcgcg
    17281 caccggcgcc accgctccca cgccgtggcg cccgtggtgc tggccgtggt caccggaacg
    17341 accatggcct tgttgctcgc gacttcctga gcgaagagcg cggtgacagc acagttcagc
    17401 ccagggcacg tcggggtggt ggctggagcc gtttgggccc agtcaaggcg atgctcgacg
    17461 ccatcaagga cggctccgtc tcctcggagc gttcgcaccc ctgaccgccc ggcgccggcg
    17521 gcccgcgggt ctcccggcgg ccggtatcgc cacggcctgg cccgccaggg cgaacgtgcc
    17581 ctccctgcgg accgtgtgcc agcgcagccg cgcgcccagg accgccgtgg ccacggactg
    17641 gatgacgacc agatacatca gctgccggta gacgaactgc tgcagcggca gcgcccacag
    17701 caccgaggcg cgttcgccgt ccaggcgcaa cgcgtaccag ccggtgaggg cctgcagtgc
    17761 gacgaagccg gcccacaccg cgaccaccgg aagagggtcg ccgacgagca ggccgtacat
    17821 cgccatgacg tcgacgacgg gggccagcag cggcaggatc acctggaaca gcgcgagata
    17881 tccgaggcat cggcggccga agggccggcg ctccacgatc gccccgcggt gcttccagat
    17941 cgcctgcagc gtgccgtagc accaccggta ccgctgccgc cacagctggc tgagcgaggc
    18001 gggcgcctcg gtccatgcgc gggcccgctc ctcgtagacc acccgccagc ccctgcggca
    18061 gatcgccatg gtcagatcgg tgtcctcggc gagcgtgtcc gcgctgacgc ccccggccga
    18121 ggccaccgcc tcgcggcgga acgcgccgat cgcccccggc accgtcgcca tgcagccgag
    18181 caggtcgaac gcgcggcgat ccaggttgaa cccgacgacg tactcgatgt gctgccagcg
    18241 cccgatcagc cctcgccggt tgccgacctt ggtgttgccg ctgaccgcgc cgaccgtccg
    18301 gtccgcgagc ggtcgtacga ggtggccgat ggtcgggggc tcgaagacgg tgtcgccgtc
    18361 gaccatgacc aggacgtcgt gggcggcgtg ggcgatcccg gtggtgagcg cggcgggctt
    18421 cccggcgttc ggctgccgga tcacccggac cccgggcagt ccgagcgagg cggcgatcgg
    18481 tcccgtcccg tcggtggagc cgtcgtccac gacgacgacc tcgacccggc cggggtagtc
    18541 ggtcctgacc agggaccgca ccgtcgcctc gatccccacc tcctcgttgt acgcggggac
    18601 gatcaccgag accggcggcg ggaccgccca cggggggacg ccggtgttcg ggggccgtcc
    18661 ccgcgtcctg cgggcgtgcg cccacgccag cgcggcgaac agggccgacc tcagcagggt
    18721 gagcgcgccg gccgcggcga ggaaccagcc gagcgcctcg acgagggcga aggaggcgcg
    18781 ctgggcgaat gacaggaccg tgccgaggac gcgctcgccg ggggcggcgg ccgtgtgcgc
    18841 cgtggggagc ccgacggcgt ccgtgagcgt ggtcgcggtg tatcccttct tctccagccg
    18901 ggtgagcagc cggtcgacgg cggccagcgt ccgggtgcgg tcgccgcccg agtcgtggaa
    18961 catgatcacc gcaccctcgc cctcgaccgt gcgcgcgagg gacgcgagga ccatctcgtc
    19021 cacgggcggg cggctccagt cgcccgtgtc cacgtcggtg aacgtcacca ggtatccctc
    19081 gtcgccgagc agccgcatcg ccgcgagctg cccgtacccg accgcgccgg gggccgagga
    19141 gtacggcatg cgggcgaggc gggtgtggat gccggccgct gcggccagcg tcttctgcgt
    19201 cagggacatc tccacgcggg cccgccaggc cggcacagcg cccaggtcgg cgtgggtgta
    19261 ggtgtggttg ccgatctcgt gcccctcggc gaccagccgg cgggcgagct cggggtgctc
    19321 ggccacgtgc gcccccagca cgaagaaggt cgccttcgcg tggtgctcgc ggagcaggtc
    19381 gagcagccgg ggagtccagc ggggatcggg accgtcgtcg aaggtgagcg ccaccgtgcg
    19441 cggcttgggc cgcgcgctga gcggccgcga ttccgagacg ttgaccagag ggccgccgga
    19501 gcggatccgt tcgagctcgg cggagtcgcc gtagtcggcc gggggcggcc gggtctcgcc
    19561 gacgacgttg tgcgcgtacg cgttgagcag cagcgctccg gacatgagca gcgcggcgat
    19621 cgcgacgagg aaccagtgac cgcgcggctc gggaggtctg cgctggactg gtctgctctg
    19681 ggccggtctg cgctgacgcc tcactgggtc gtgccgggag tctgcccggg ctgcccggga
    19741 ggcgtctgga ccgcgctggg ccccggcgcg ggggtccgcg tgagctctcc ggacggcgcc
    19801 gtggccggcg ggacctccgg ttcggacgac ggcgcgggcg cggactgccc ggacgaggag
    19861 atctccacgt ccggctcacg gcccgccgga ggcgtcgtgc tcggcttcag gctcccgcgt
    19921 ggggaaggcg aggcggaggg gaccctgctc ggcaggccgc ggccggaggt cgcccgccgc
    19981 gcggccgccg tcgagtgcgg cgtgccgctc gcccggggga cacgcctgtg ctcggatctg
    20041 tgcccggagc tgggggacgc ggtgggggag cccgtggggg agcgttccac cacctgctgt
    20101 ccccgcgtgc cgacccagcc catcgggggg agttcggggc ctgtcagtgc tccgctcacc
    20161 agggtgagcg tcagcgcgag gacgacgatc gccccgccga ccgcggcggc tgtcaagatc
    20221 ttggcccggc gtccgctgtg gtccacgaag acggccgtac gcgccgggtg atgatcttcc
    20281 acgaagcatg atcgtacgcg agtcgaaagc agcttcgaga agttcgaacc atttcgtgat
    20341 ccgagggttc cggctttccc gatgccccgt gcggagaacc cctgggatgc gttcggttga
    20401 ggctcccggc gggggtgggg ctggttaaat gggcgcagca ccggcccctg gtgtgaacgc
    20461 acggacgaag ttgacgtttg tgctgttatg gggtgatatc aggtgcggtg gtgccgggct
    20521 ttcggtcaat ggggatcgga agggacgcgc ccatcgtgga ggagtggcgc atgcctgcga
    20581 cgccgtacgg ccgagctgga tcgggggacg tgctgccccc gccccgtagc ttcggcgagg
    20641 agggcggacg cctctcctac ggcggctatc tgcgcctgcc cgagctgctc gcccagcagg
    20701 agcagcggtc cggggccagc gacgagctgc tgttcatcac cgtccaccag gtctacgagc
    20761 tgtggttcaa gctcctgctg cacgagctgg agcggatcag ggacgcgatg gtcgagggcg
    20821 cgctgtggcg cgccaggcac ctgttccgcc gcgtccacgc ggtggagaag gtcatggtcg
    20881 accaggtcca ggtgctggag acgatgacgc cgcaggactt cctggagttc cggtcggtcc
    20941 tcgcccccgc gagcggcttc cagtcggtcc agttccgtga gctggagttc ctctccggcg
    21001 ccaaggaccc ctcgtacctc ggccggctca gggacgccga cgacgcggaa atcgccaggt
    21061 tgcggcggcg gctcgccgaa ccgtccctgt gggatgctta cctcatcgcc ctctcccagc
    21121 ggggcctgcc ggtctccgac gaagagatca tggaatccct gctggccgtg gcccgtgacc
    21181 gggggtcgta cgacgatctg tgggacctgg ccgaagatct cctcacgcac gacgagacca
    21241 ccgcactctg gcggatgagg cacgtgcaga tggtggagcg ccagatcggc acgaaatccg
    21301 gtacgggagg ctcgtccggg gcaccgtatt tgaggggacg gacgcgtttg cacttctttc
    21361 ccctgttgtg ggaactccgg gcctggcttt gaatcctcac aagggagtga gtagcgacat
    21421 gccgctcgaa atggcgctag atcggcagga atcggacgaa gcgttggatg agcttctccg
    21481 tctcgccgcc gagaggtgcg cgcacgcgcc gggagcgctg caggtggagg gcgaggatcc
    21541 cctggccttc ctgaggcggt actaccgcaa cgtccccgtc gaggacctga tcgaccgcga
    21601 cccggtggac gtgtacggcc ccgccatggc ccaccgccac ctggcccagc accggccgca
    21661 gggacgcgcg ctggtccgcg tctacacccc caccctcgag gagtgcggct gggacccggg
    21721 ccgcaccgtg gtccagatcg tcaccgacga catgccgttc ctggtcgact cggtgacgac
    21781 cgagctggac cggcacgaga tcggcaccca cctgatcgtc cacccgcaga tgcgggtgcg
    21841 ccgggacatg accggcgaac tgctcggcgc gggccaggag gacgtgaccg ggcaggtcgt
    21901 ccgcgagtcg tggatgcaca tcgagatcga ccggcaggcc gatcacgacg tgctcaagga
    21961 actggagagc gacctgcagc gggtgctgct cgacgtgcgc tgcgcggtcg aggacttcgc
    22021 caagatgcgg gcgctggccg tgcagaccgc cgaggacctg g
//
