LOCUS       NZ_JABBXA010000004     23709 bp    DNA     linear   CON 07-NOV-2024
DEFINITION  Microbispora sp. H13382 NODE_4, whole genome shotgun sequence.
ACCESSION   NZ_JABBXA010000004
VERSION     NZ_JABBXA010000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora sp. H13382
  ORGANISM  Microbispora sp. H13382
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 488556)
  AUTHORS   Liu,C.
  TITLE     Selective isolation, identification and anti-microbial activity
            study of Microbispora
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 488556)
  AUTHORS   Liu,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-APR-2020) Microbiological Resources Collection Center,
            Sichuan Industrial Institute of Antibiotics, 168 Huaguan Road,
            Chengdu, Sichuan 610052, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014161445.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 07:22:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,982
            CDSs (total)                      :: 7,906
            Genes (coding)                    :: 7,786
            CDSs (with protein)               :: 7,786
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 21 of 121
            Pseudo Genes (incomplete)         :: 104 of 121
            Pseudo Genes (internal stop)      :: 8 of 121
            Pseudo Genes (multiple problems)  :: 11 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:45:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 387965
            Orig. end                         :: 411674
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABBXA010000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23709
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23709
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23709
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13709](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13709)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    331..344
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.76"
                     /tool="antismash"
     misc_feature    1351..1366
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.24"
                     /tool="antismash"
     gene            1536..2000
                     /locus_tag="HHX41_RS11525"
     CDS             1536..2000
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039673.4"
                     /locus_tag="HHX41_RS11525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6157 family protein"
                     /protein_id="WP_220503939.1"
                     /transl_table=11
                     /translation="MAEDLNYYSTLIAVADDCPVDAAEVPKPRGGRPTVAVLQYELISG
                     APYGLTQEDVLFETWLRRQDPPPEDLSEQRRAELRKEFFSRSQACLRASPLPKKHGWGL
                     LFDRDGRIALCPMESEEYRRLVEGRAGGPGDSDTGDGGVRVLKAMRSRRS"
     misc_feature    complement(1537..1551)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.07"
                     /tool="antismash"
     gene            2192..2860
                     /locus_tag="HHX41_RS11530"
     CDS             2192..2860
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890004.1"
                     /locus_tag="HHX41_RS11530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_182905932.1"
                     /transl_table=11
                     /translation="MSGVELSVRIPVGGVVLDADVVVPGEARGAVLFAHGSGSGRHSPR
                     NRYVAGELQRAGLATVLADLLTVEEERADAVTGHLRFDIGLLAERVGGLADRLPGDEGV
                     GGLPVGLFGASTGAAAALVAAAARPGGVGAVVSRGGRPDLAGDALRSVRQPTLLIVGER
                     DSVVLDLNRTAMRAITAPVELEIVPRATHLFEEPGALETVARLARDWFLRHLAGGAPPA
                     "
     gene            2885..3862
                     /locus_tag="HHX41_RS11535"
     CDS             2885..3862
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017568996.1"
                     /locus_tag="HHX41_RS11535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldo/keto reductase"
                     /protein_id="WP_182905933.1"
                     /transl_table=11
                     /translation="MEQRVLGRTGRQVGVVGLGAWQLGADWGEVSEADALATLNAAVDA
                     GTTFIDTADVYGDGRSEKIIGKLLKERSGLTVATKMGRRVQQTPDVYTLDNFRAWTDRS
                     RANLGVDTLDLVQLHCPPSAVFDTDEVFDALDTLVSEGRVAAYGVSVETVTEALTAIAR
                     PGVATVQIILNAFRLKPLDEVLPAAEKAGVGIIARVPLASGLLSGKYGPQTVFSEDDHR
                     NFNRQGEAFDVGETFSGIEYGVGLQAVDRLRGLVPEGMTMAQFALRWIIDQPGVSVVIP
                     GARNPGQAEANAAAARFPALPAETHDTVREVYDDLIRPQVHHRW"
     misc_feature    complement(3914..3931)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.07"
                     /tool="antismash"
     gene            4120..4902
                     /locus_tag="HHX41_RS11540"
     CDS             4120..4902
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546041.1"
                     /locus_tag="HHX41_RS11540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carotenoid biosynthesis protein"
                     /protein_id="WP_259400868.1"
                     /transl_table=11
                     /translation="MAGADGVVGMAGAVRMVRLVGVVALAAMTAAQIATGLRPHDLRLT
                     TVVVVLLAVSALAFAAAAYGPGRAAGAFAAAVTAGFAAEWAGTRTGLPFGDYRYTDALW
                     PRPGGVPLVVALAWGGMGLAAHAVARRVAPRGRLIPILAGALALTAWDLFLDPQMLRLG
                     LWVWAEPGPYRGVPLGNFAGWLLVSLLVMTLIDRLTGRTDGGRAGATGLVVLYTVMAAM
                     ETVGFAVVFRPPDPLVAAAGGLAMGTFALLAWGRAWRR"
     misc_feature    4166..4181
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            4890..6434
                     /locus_tag="HHX41_RS11545"
     CDS             4890..6434
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546040.1"
                     /locus_tag="HHX41_RS11545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_220503940.1"
                     /sec_met_domain="DAO (E-value: 2.6e-10, bitscore: 35.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEVIVVGGGVGGMVAALLLARDGHEVRVYERLPRLGGKLAEHRR
                     DGFTFSIGPSLLTLPGLFLDLGVPLDLLELDELCRYRWPDGSALSTYRDPERTAEAVDR
                     LAPGEGRHWRAYHRWAGRCLDASMRTFFAGPLSGPVVEPPIPWSGRRAAGITGGRPGAG
                     RRGPVPRPRPGDLLAVAPGRTLDALAGRFFRDARLRQYVGRYATYAGSNPYRAPAALGC
                     VPAIEHGDGGWYVRGGLPRLADALAASLDKAGVDVHLETEITELIPGPGRVGGVRTARG
                     EAVRADIVIVNADAAALYGRLLPDRARLRRIAGLGLSSSAFLLLAAVEGRTEGMPHHSV
                     VFSADYRREFGDIFDRRRPPEDPTVYIACPVADDPTQAPAGAESWSMLVNVPAGDPARW
                     PLPPEAYAELVLGRLASRGHDLSGRLRFLDLLTPADLRDRYGAWGGAIYGGAYGGPLAP
                     FRRPGNRGPLRGLYLVGGSAHPGGGLPLVAMGGRIVAALVRRDFPSSARRPGKAHP"
     gene            6431..7675
                     /locus_tag="HHX41_RS11550"
     CDS             6431..7675
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546039.1"
                     /locus_tag="HHX41_RS11550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_182905934.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-23,
                     bitscore: 78.5, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTSAARTVGCTRAGRAGWAGTAARVLAAAQAVAALVVVARLARG
                     RRRLPPLTAPLPDPPPGAGGPPGGGCPGISVVIPARDEERRLGPCLRAVLADPAVTEVI
                     VVDDESSDGTARIAAACGATVVRGRPLPDGWVGKQWALHQGLSEARGEIVVTLDADTRP
                     RPGLFGALAAALRDHDLVSAGPRFVCEGLAEQALHASFLTTLVYRFGPIGPPAPPPPHR
                     VVANGQCLAFRREAMRRADGFARVRGHMTDDVALARALAACGWRVGFLDAGGLLEVDMH
                     ESAADVWREWGRSLPLRDVTRPAWQAADLAVVWLTAALPALRLAAGRPTRLDLALLAVR
                     VLLTTALRRSYARPGAGVALSFLLDPATAVRLTQATLRPVRTWRSRAYPVYPAAGAGAV
                     RRGARPAPPARSAAR"
     gene            complement(7626..8240)
                     /locus_tag="HHX41_RS11555"
     CDS             complement(7626..8240)
                     /EC_number="2.3.1.275"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0043772 - acyl-phosphate
                     glycerol-3-phosphate acyltransferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890493.1"
                     /locus_tag="HHX41_RS11555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycerol-3-phosphate acyltransferase"
                     /protein_id="WP_310741930.1"
                     /transl_table=11
                     /translation="MTTLPPLIPLLVALIGGYLLGSVPVAVLVAGRRGVDPREIGDRNP
                     GFWNVRERLGGRTAAPVFAGDMAKGVLAGLLGLLAGGAHTTGPGVVAGPSVPTAYLAVG
                     AAMIGHAWPVFAGFRGGRSVLTFAGGIAVICPPAFGLALAVLGVVFLLTRSFAAGARAG
                     VFAIPLLQLPFAPIGHVAATGALMCLIGLRFGQAALAARRA"
     gene            8197..8967
                     /locus_tag="HHX41_RS11560"
     CDS             8197..8967
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546037.1"
                     /locus_tag="HHX41_RS11560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="spheroidene monooxygenase"
                     /protein_id="WP_259400869.1"
                     /transl_table=11
                     /translation="MSATSRGMSGGSVVTFHLQRYADRGAMRHMAFDRPVLRRTGGLLF
                     WRLLGSGRGASTTLGADLRRWALLAVWRDERALEEFLARSPIPARWRREAVEAWHVRLA
                     PIASRGRWNGVEPFTPVSRLPGPPGRAGSHATAGPEDGPVAVLTRASIRPSRLVAFYRS
                     VPAVERWLRAQEGCLASVGLGEWPLARQATFSLWRDAAAVRAFAYAGRAHREVVERVRA
                     HDWYSEELFARFIPYASVGTWGGADPLAGRRTAQ"
     gene            complement(9030..10001)
                     /gene="plsX"
                     /locus_tag="HHX41_RS11565"
     CDS             complement(9030..10001)
                     /EC_number="2.3.1.274"
                     /GO_function="GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="plsX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133541.1"
                     /locus_tag="HHX41_RS11565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="WP_182905937.1"
                     /transl_table=11
                     /translation="MSRPVVVDAMGGDHGPAEIVRGAVEAWREHGVPVVLVGRAGVVRG
                     ELARLGAAGEIDVVHAAEVVPMTERGAGAVRMVRSSLSVGFDLLREGAGAAFVSAGSTG
                     AVVACAADRLGTAPAVLRPALAVALPTTAGGVTVLVDAGATVDPMPEMIAQFALLGASY
                     AQLVLGVADPRVGLLSIGAEPGKGNRLTRRAETLLRGLPLRFHGNVEGGDVLTGVVDVI
                     VTDGFTGNVVLKNVEGTVRATLALAAAEGVAGPAGLRRVAARYDPETHGGAALLGLTGT
                     VVVAHGSSRAGTVARACVVARDLAEGEVVARLGDRLAVQPAP"
     gene            complement(10001..10921)
                     /locus_tag="HHX41_RS11570"
     CDS             complement(10001..10921)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890490.1"
                     /locus_tag="HHX41_RS11570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_169983152.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.6e-97, bitscore:
                     319.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.2e-68,
                     bitscore: 224.8, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPPQTPAATLTAGYERCRRLHASYGRSYYLATRLLPAWKRPHV
                     HALYGFARYADEIVDSFAVTGDRAAALERLSSRLAAALDGEHVRDPVLPAFTHTVRAFG
                     IDQADVRAFLASMRADLTVDRYATYDDLLGYMEGSAAVIGTMMLPVLEALPGEEGRARE
                     PARQLGLAFQLTNFIRDVREDLTRGRVYLPLADLDKFGVTEADLAAPYAAPAVRELVAY
                     ECDRARDHYRRARDGIALLAPSSRPCIRAAYELYGGILDEIGAAGHDVLARRARVSRRR
                     RLAIFTRHLFAARAAARAERRVEVA"
     gene            complement(10918..12420)
                     /locus_tag="HHX41_RS11575"
     CDS             complement(10918..12420)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546035.1"
                     /locus_tag="HHX41_RS11575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_182905938.1"
                     /sec_met_domain="DAO (E-value: 2e-12, bitscore: 42.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAGGPVVVVGAGLGGLAAAMRLAGAGREVTVVEAADVPGGCCGT
                     AALGSHRVDIGPSVLTMPGVLADTFAAAGQDLERWLPLRRLDPYYRLTFHDGSRLDVVA
                     GADAMAERVRALCGPAEAVRYRRFRQLLGEMFEAEWSAFIDRDMTRLRALARPYALVRL
                     AALGGFRRLDGLVRRHLTDERLIRAHTFQALYVGLSPRRALGVYAVIAHMDTVGGVYFP
                     REGGMHAVPRAMAAAAEKAGAVFRYGVRATRIETDGAGVVAVRLDTGERLAARHAVVAC
                     DLLRAHGRRDGDGLLPEEAADWRLRRPRLSPSCLVAHFALDRRPDGQAHHTLHFGREWE
                     TTFAELEAGRPQPDPSLLVTCPGPDDHGPGDHGPGGGGPAVLSVLEPAPNTRGGADWTA
                     LTPRLVDRMLGRLAGLGYGDLSGTPRLVFDPPAWRRRGHSAGTPFALDARFTQTAWFRP
                     SGAARRVPGLHFAGMYTAPGVGVPPVLISGRLAAERILESTP"
     gene            complement(12417..13709)
                     /locus_tag="HHX41_RS11580"
     CDS             complement(12417..13709)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630832.1"
                     /locus_tag="HHX41_RS11580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_182905939.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-45, bitscore:
                     150.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTLTRETGGVRDETREPSDHHLSGPSDGALFDRTLSFDRTLFDR
                     ALDELLRREMDRLSFLGAEDRETLRRHLAGFVARGGRRLRPAFVYWGHRASGGSPDDLD
                     AVLAAGCSIELLHACALILDDVMDESPLRRGRVTAHVALAERHREGGWAGSSRRFGESA
                     AVLLGMLAFTWADSALLADRRRLADALEVLTQLRVELAAGQYLDLTCAARGGGGRREAL
                     LISTYKSGKYTVERPLHLGHAIAGGEPGLRRVLSAYALPLGEAFQLRDDVLGVFGDPAR
                     TGKPAGADLLQGKRTYLLALARERADGPGAALLDALPRPGEARPDALPKPGEAPPDLVA
                     AAREVIVATGALETVERRIGDLTEAAAGALSGADMPADARSALLDLARRLTHPDPTGLL
                     ARTCRAQPDPARPGPAPLSESAGPSTGGARR"
     gene            14023..15054
                     /locus_tag="HHX41_RS11585"
     CDS             14023..15054
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546033.1"
                     /locus_tag="HHX41_RS11585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_182905940.1"
                     /transl_table=11
                     /translation="MADEDAPGAGENAAAEEEPGYGIGAVSRRLGVPASTLRTWNLRYG
                     IGPSRRSPGGHRRYDDADLRRLEEMNRLIRAGMPPADAARQALRPRSAPGERAAPPAGP
                     GAAAPPESRAGSSAPSESHESPEPRVAPAPAVRQAPEPGLLSAVMLARAVTALDAPTVS
                     VGLDTALTTHGVVWTWERLVLPVFAAVSRRQQDTCAGIDVEHLFSERLQVALARFAARA
                     PAPVHPRPVLLAAAEEEQHALPVHALAAALGTLGVETRVLGARTPYRALADAMRRLGPA
                     AVFVWSQMRETGDPAPLADLPRLRPACRVVAGGPGWGDHLPAEVVRVTTFRDAISAVMT
                     TLR"
     misc_feature    15070..15079
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.92"
                     /tool="antismash"
     misc_feature    15104..15120
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.52"
                     /tool="antismash"
     gene            15169..15690
                     /locus_tag="HHX41_RS11590"
     CDS             15169..15690
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888348.1"
                     /locus_tag="HHX41_RS11590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_169983148.1"
                     /transl_table=11
                     /translation="MEETLEFRLAAGDAGALGECYRAHSPAVRSYLRRLVPPQDVEDVL
                     QVVFTEVWRFRHRFDPGRSLSAWLFGIARNRAVDHLRARTPTTVPLEAVPDPAGHDGRL
                     DGDELADRDRVRRALAALPHVQRQAIELAYYGDLTQREIAEHLRVPLGTVKARTARGLH
                     RLSTLLRTAA"
     gene            15693..16658
                     /locus_tag="HHX41_RS11595"
     CDS             15693..16658
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888347.1"
                     /locus_tag="HHX41_RS11595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF523 and DUF1722 domain-containing protein"
                     /protein_id="WP_182905941.1"
                     /transl_table=11
                     /translation="MEPAEEIRPRVAVSSCLLGAPVRFNGGHSRDRFLTGDLSEYVNWV
                     PVCPEIEIGLGAPRETLRLERSAQGARLMTRRTREDLTAPMTALAAERAAGLGDVDGYV
                     FKSRSPSCGLHGIPVYAGESGPADRRGRGIFAAAIAGARPELAVEDEGRLHDAVLREAF
                     VERIFASARLRALLAGDWHPRDLVAFHARHKMQILAHAPAAYREIGRLVAAAGERPRDA
                     LAGEYARAFRTALAARATVGRHVNVLHHCLGMIGRELDPVRRADLAEVIASYRARRVAL
                     TVPLALLRHHARGAGVDYVRDQTYLSPYPDALRLRNHVPA"
     gene            16687..17193
                     /locus_tag="HHX41_RS11600"
     CDS             16687..17193
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015060.5"
                     /locus_tag="HHX41_RS11600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TspO/MBR family protein"
                     /protein_id="WP_182905942.1"
                     /transl_table=11
                     /translation="MRSTSTKTLLRTALAVTAAAAVGGLSTDARSGWYRRLRKPSWQPP
                     PQAFGLVWTPLYATIAYASARALSRAGDGSRPALRRALAVNLALNAAWPPLFFKARNPR
                     LALAEILALDVSNALLTRRLLREDRTAGLLLLPYAGWTVFATALNAAIARHNPQARRDP
                     GAQGA"
     gene            complement(17271..18044)
                     /locus_tag="HHX41_RS11605"
     CDS             complement(17271..18044)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX41_RS11605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_182905943.1"
                     /transl_table=11
                     /translation="MSCTRVCLAIAVAGTAVLVPTAQASAGTPGPAAVMSKALVQGRGV
                     AFTETSKSWIGDDRSDATVFRNSGVLAFGRGRLAAASVKRVTTSGKTFRFLIVGGRTYA
                     QGGLWSDSLPAGKSWVRSRDLRLEPYQASGQAIDVFEPATLRAVYATRSGGAVHQSVNG
                     VPATRYSGTVTAKALCTVSAACREAFGKSSPVKIGWSLWLDGKGRVVRLTTQWSRRSDS
                     RKGVAGGGEWTDTYYARWGARITVKAPPASRVATV"
     misc_feature    18064..18078
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.07"
                     /tool="antismash"
     misc_feature    complement(18067..18082)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     misc_feature    18100..18111
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.83"
                     /tool="antismash"
     gene            complement(18220..18723)
                     /locus_tag="HHX41_RS11610"
     CDS             complement(18220..18723)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017534457.1"
                     /locus_tag="HHX41_RS11610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_169983144.1"
                     /transl_table=11
                     /translation="MPGTRWLDEEEQRTWRAYLRTSQLLQEALERQLQRDSSMPHAYYM
                     ILVVLSESPGRTMTMTELSAILQYSVSRLSHAVSRLEEKGWVRRLKRPEDRRTTVAELT
                     DEGFAAIVKAAPGHVDEVRRVLFDPLTPGQVRQFREILATILAAFEHRADESELPRELD
                     TAAQ"
     gene            18809..21109
                     /locus_tag="HHX41_RS11615"
     CDS             18809..21109
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891915.1"
                     /locus_tag="HHX41_RS11615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoketolase"
                     /protein_id="WP_182905944.1"
                     /transl_table=11
                     /translation="MNAYGNIDAYWRAANYLSVGQIYLMDNPLLTEPLRPEHVKPRLLG
                     HWGTTPGLNFCFAHLNRIIRERGQDMIYIAGPGHGGPAAVAHAWLEGTYTERYPHITRD
                     AEGMRRLFRQFSFPGGIPSHVAPETPGSIHEGGELGYALSHAYGAAFDNPGLVVACVVG
                     DGEAETGPLATAWHSNKFLNRDTDGVVLPILHLNGYKIANPTVLARIPEEELVKLFEGY
                     GYRPHIVSGHEPAEMHELMAGTLDTVFGQMADGGPLPMIILRTPKGWTGPREVDGLPVE
                     GTWRAHQVPLTDVRDRPDRLEYLEEWMRSYRPEELFDADGRPVETITGTVPDGPLRMSA
                     SPHANGGELLRPLVLPDFRDYAVEVKAPATASSEPTRVLGAFLRDVIAANPANFRLLGP
                     DETASNRLSAVFEATGKEWEAALLPTDENLGPGGRVMEVLSEHQCQGWLEGYLLTGRHG
                     LFNCYEAFIHIVDAMFNQHAKWLESSRKIPWRRPVASLNYLLSSHVWRQDHNGFSHQDP
                     GFLDVVVNKKAEVVRVYLPPDANTLLSVADHCLRSRDYVNVVVAGKQPVLDLMSMDEAV
                     VHCTRGLGILDWASTDEGADPDVVLACAGDVPTLETLAAAALLREHLPELRIRVINVVD
                     LMRLQPASEHPHGLPDVEFDALFTTDKPIIFNFHGYPWLIHRLTYRRTGHDNLHVRGYK
                     EEGTTTTPFDMAMLNDIDRFHLVMDVIDRVPGLGSRAAHLRQRMADARLRARAHTREFG
                     EDPAEIRDWTWPF"
     gene            21285..23261
                     /gene="thrS"
                     /locus_tag="HHX41_RS11620"
     CDS             21285..23261
                     /EC_number="6.1.1.3"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrS"
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011292531.1"
                     /locus_tag="HHX41_RS11620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="threonine--tRNA ligase"
                     /protein_id="WP_169983142.1"
                     /transl_table=11
                     /translation="MSAALEIRITLAGAERVVAAGTTAGEALGADGRSVIAARINGEPR
                     DLAAEVAEGDVVEPVEIDSPDGRAILRHSTAHVMAQAVQEIFPEAKLGIGPPVENGFYY
                     DFDVREPFTPDDLKRIEKRMREIVKQGQSFRRRPVGDDEARAELAAEPYKLELIGLKGG
                     AAEAADGANVEVGGGQLTIYDNLDPKSGELCWKDLCRGPHLPTTRVIPAFKLMRSGGAY
                     WRGSEKNPQLQRIYGTAWESREKQDEYLKFLEEAEKRDHRKLGAELDLFSFPDELGSGL
                     PVFHPKGGVIRRVMEDYSRRRHEEAGYSFVNTPHITKDNLYKISGHLDWYADGMFPPME
                     LEGARYYLKPMNCPMHNLIFRARGRSYRELPLRLFEFGTVYRYEKSGVVHGLTRVRGLT
                     QDDAHIYCTREQMRDELTSLLRFVLDLLRDYGLEDFYLELSTKDPEKFVGSDETWEEAT
                     QTLREVAESEKLELVLDPGGAAFYGPKISVQARDAIGRSWQMSTIQLDFNLPERFGLEY
                     QAADGTRQRPVMIHRALFGSIERFFGVLVEHYAGAFPAWLAPVQVVGIPIADAHAPYLQ
                     DVAKRLREQGIRIEVDESDDRMQKKIRNAQKAKVPYMLLAGDDDIAAGAVSFRYRNGEQ
                     KNGVPIDQAIDEIVDAVRRRIQV"
     misc_feature    23600..23615
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.0"
                     /tool="antismash"
ORIGIN
        1 ctgtcgcccg cgctggcgca gcgggcggga cagctgttcg agtgggacaa gcgcttgccc
       61 aaggtcacgg tgaccaacac cgctctggcg ggaatcctgc gccagtcgca cgacgacctc
      121 ggcgcgctgc ggctcttcga tcccgagcat cccgagctgc cgcccaccgt cgcggcgggg
      181 gcgccctggt tcatgacgct gttcggccgc gactcgctgc tcacctcctg gatggccctg
      241 ccgctcgacc ccgaactggc gcacggcacg ctgggccggc ttgccgccct gcagggcacc
      301 aaggtcgacc cgctgaccga ggaggagccc ggcaagatca tgcatgagct gcgctacggc
      361 gcccggcagg acgacacgtc ggccggcggg cacgcctact acggctcggt cgacgccagc
      421 ccgctgttcg tcatcctcct cggcgagctg cgccgctggg gcctgcaccg ggcggcggtg
      481 gagcggctgc tcccgcacgc cgacgccgcg ctggagtgga tcgagcggta cggcatgcgt
      541 gacgggttcc tgtggtacca gcgcaagacc gaccagggcc tgctcaacca gggctggaag
      601 gactccttcg acggcatcaa cttcgccgac ggcacgatag cccggccgcc catcgccctg
      661 gccgaggtgc agggatacgt ctacgccgcc tgcatcgccc gccactactt cgcccaggag
      721 gcgggcgaca ccgagaccga gcggcgctac cgggagcggg cagccgcgct gcgcgcccgg
      781 ttcaacgaac ggttctggct gccccaccgc ggctacttcg ccatcgggct cgaccacgag
      841 ggccgcccga tcgacgcgtg cgcttcgaac atgggccact gcctgtggtc ggggatcgtc
      901 gaccgcgaca aggccgccgc cgtggccgag cacctgctgt caccccggat gttcaccggc
      961 ttcggcatcc gcaccctcgc ctccgacatg ggcagctaca acccgatgag ctatcacaac
     1021 gggtccgtct ggccccacga cagcgcgctc gtcgcggccg ggctcatgcg ctacggattc
     1081 gtggacgggg cccagcgcgt cgccaccggc ctgctcgacg ccgcccgggc cttcggcgac
     1141 cggttgcccg agctcttctg cgggttcgac cggggggagt tcgacgtgcc ggtgccgtac
     1201 ccgacctcgt gctcgccgca ggcctgggcc tcggccaccc cgatccagct cgtacggctc
     1261 ctgctgcgca tcgacccgtg ggtgccgtac ggcaaggtgt ggatcgcgcc ggcgctgccg
     1321 gaggggttcg gggacctgcg catctccgga atgccgctgg cgggtacgcg ggtcgacctg
     1381 gaggccaggg agggcagcgg cgcggtgcac gtgtgcggcc tgcccgaggg ggtgcgcctc
     1441 atcccggagc cgcgcccggc ggggacgtcc ggcgcccgct cctgaccccc ggccgccccg
     1501 ggccggccgc cgatcgatcg gggcatagtg gagccatggc cgaggatctc aactattact
     1561 cgacgctcat cgcggtcgcc gacgactgcc cggtggacgc cgcggaggtg cccaagccca
     1621 ggggcggcag gcccaccgtc gccgtcctgc agtacgaact gatctccggc gcgccgtacg
     1681 gcctgacgca ggaggacgtg ctgttcgaga cctggctgcg ccggcaggat ccgccgccgg
     1741 aggacctgtc cgaacagcgg cgcgcggaac tcaggaagga gttcttctcc cgttcccagg
     1801 cctgcctgcg ggcctcgccc ctgcccaaga agcacggctg ggggctgctg ttcgaccggg
     1861 acggccggat cgcgctgtgc ccgatggagt cggaggagta ccggcgcctg gtggagggcc
     1921 gggccggcgg cccgggagac agcgatacgg gtgacggcgg cgtgcgcgtg ctcaaggcga
     1981 tgcgctcgcg ccgctcctga cgccgtccgt ccccacgggc gggccgcgcg ggtttgccgg
     2041 gaccggccgg gggtacgccc ggttgttccg cagaggtcgg cagagtcggc aaaggtcagc
     2101 aaaggtcggc aggcaaaggt cggcaaaggt cggcggagtt cattggagtt cagcgcggtt
     2161 cagccgggcg cggccgggga gggcgggcgt catgagcgga gtcgaactca gcgtgcggat
     2221 ccccgtcggc ggggtcgtgc tcgacgcgga cgtcgtggtt cccggggagg ccaggggggc
     2281 ggtgctgttc gcccacggca gcggcagcgg ccggcacagc ccgcgcaacc gctacgtcgc
     2341 gggggagctg cagcgggccg gactggccac cgtcctggcc gacctgctca cagtggagga
     2401 ggagcgcgcc gacgccgtca ccggccacct ccgcttcgac atcggcctgc tggcggaaag
     2461 ggtgggcggg ctggccgacc ggctgcccgg ggacgagggc gtcggcggcc tgcccgtcgg
     2521 gctgttcggc gcgagcacgg gcgccgccgc cgcgctcgtc gccgcggcgg cgcggcccgg
     2581 cggcgtcggg gcggtggtgt ccaggggcgg caggcccgac ctcgcggggg acgcgctccg
     2641 ctcggtgcgc cagccgacgc tgctgatcgt gggggagcgc gactccgtcg tcctcgacct
     2701 caacaggacg gcgatgcggg cgatcaccgc gccggtggag ctggagatcg tgcccagggc
     2761 cacgcatctg ttcgaggagc cgggcgccct ggagacggtg gcgcggctcg cccgcgactg
     2821 gttcctgcgc caccttgcgg gtggagcgcc ccccgcctga gctgccccgc tacgatctga
     2881 cctcatggaa cagcgcgtgt tgggcaggac gggcaggcag gttggcgtcg tcgggctggg
     2941 agcctggcag ctcggggccg actggggcga ggtgagcgag gcggacgccc tggccacgct
     3001 caacgccgcg gtcgacgccg ggaccacctt catcgacacg gccgacgttt acggcgacgg
     3061 ccgcagcgag aagatcatcg ggaagctgct gaaggagcgg tccggcctga ccgtggccac
     3121 gaagatgggc cgcagggtgc agcagacgcc cgacgtctac accctcgaca acttccgcgc
     3181 ctggaccgac cgatcccggg ccaacctggg cgtcgacacg ctcgacctgg tgcagctcca
     3241 ctgcccgccg agcgccgtct tcgacaccga cgaggtcttc gacgcgctcg acacgctggt
     3301 ctccgagggc cgcgtcgctg cgtacggcgt gagcgtggag acggtgaccg aggccctgac
     3361 cgcgatcgcg cggcccggcg tggccaccgt gcagatcatt ctcaacgcct tccggctgaa
     3421 gccgctggac gaggtcctgc ccgccgcgga gaaggccggt gtgggcatca tcgcccgggt
     3481 tccgctggcc agcggcctgc tgtcgggcaa gtacggcccg cagacggtct tctccgagga
     3541 cgaccaccgc aacttcaacc gtcagggcga ggcgttcgac gtcggcgaga ccttctccgg
     3601 catcgagtac ggcgtgggcc tccaggccgt cgaccggctg cgcggcctcg tgcccgaggg
     3661 catgacgatg gcgcagttcg cactgcgctg gatcatcgac cagcccgggg tcagcgtcgt
     3721 gatccccggc gcccgcaacc ccggccaggc cgaggcgaac gcggcggcgg cgcggttccc
     3781 ggcgctgccg gccgagacgc acgacacggt ccgcgaggtc tacgacgacc tgatccgccc
     3841 gcaggtgcac caccgctggt gaccccgccg tcgcggcgtg cccgcggcgg atgagtcccg
     3901 cgtgggccgg gggcatccga tcagggggat ccgctcgaat caccctgtgt ggagacgtgg
     3961 gatgccacag agaagagggc ggccgaggct gacggcacgc ccgccgggcg gcgcggatca
     4021 cgccggccgc gactgacggg cccgtggcag gcccggccgc gcctcagcag gctgaggcag
     4081 gcccggccgc ccggcgggtc gcggccgaac gcggccggca tggccggggc ggacggcgtg
     4141 gtcggcatgg ccggcgcggt ccgcatggtc cgcctggtcg gtgtggtcgc gctggccgcg
     4201 atgacggccg cccagatcgc gacggggctg cggccccacg acctgcgcct caccaccgtg
     4261 gtcgtggtcc tgctcgcggt gagcgcgctc gccttcgccg cggcggcgta cggcccgggc
     4321 agggcggcgg gcgcgttcgc ggcggcggtg acggcgggct tcgccgccga gtgggccggc
     4381 accaggacgg ggctgccctt cggcgactac cgctacaccg acgccctgtg gccgcggccc
     4441 gggggcgtcc cgctggtcgt cgccctcgcg tggggcggca tgggcctggc cgcccacgcc
     4501 gtcgcccgcc gcgtggcgcc gcgcggccgg ctgatcccga tcctcgcggg cgccctggcg
     4561 ctcaccgcct gggacctgtt cctcgacccg cagatgctcc ggctcgggct gtgggtctgg
     4621 gcggagcccg ggccgtaccg cggtgtgccg ctcggcaact tcgccgggtg gctgctggtg
     4681 tccctcctgg tcatgacgct cattgaccgc ctcacgggcc gtacggacgg cggccgggcg
     4741 ggggccaccg ggctggtcgt cctctacacg gtgatggcgg cgatggagac cgtcggcttc
     4801 gccgtggtgt tccggccgcc cgatccgttg gtggccgccg ccggagggct cgcgatgggc
     4861 acgttcgccc tgctcgcctg ggggcgcgca tggcggaggt gatcgtggtc gggggcggcg
     4921 tcggcggcat ggtggccgcc ctgctgctcg cacgggacgg gcacgaggtg cgcgtctacg
     4981 agcggctgcc ccgtctgggc ggcaagctgg ccgagcacag gcgggacggc ttcacgttct
     5041 cgatcggccc ctcgctgctc acgctgcccg gcctcttcct ggacctcggc gtcccgctcg
     5101 acctgctcga actcgacgag ctgtgccgct atcgctggcc ggacggctcg gcactgtcca
     5161 cctaccgcga cccggagcgt acggcggagg cggtggaccg gctcgcgccg ggcgagggcc
     5221 gccactggcg ggcctaccac cgctgggccg ggcgctgcct ggacgcctcg atgcgcacct
     5281 tcttcgcggg accgctgtcc ggacccgtcg tcgagccgcc gatcccgtgg tccggacggc
     5341 gggccgccgg gatcacgggc ggacggccgg gcgccgggcg gcgcggcccc gtcccgcggc
     5401 cccggccggg cgacctgctc gcggtcgcgc ccggccgcac cctggacgcg ctggccggcc
     5461 ggttcttccg ggacgcccgc ctgcgtcagt acgtcggccg ctacgccacc tacgccgggt
     5521 cgaaccccta ccgcgcgccc gccgcgctgg gctgcgtccc cgccatcgag cacggagacg
     5581 gcgggtggta cgtgcggggc gggctgcccc gcctcgccga cgcgctggcc gcgtcgctcg
     5641 acaaggcggg cgtcgacgtt cacctggaga ccgagatcac cgaactgatc ccgggcccgg
     5701 ggcgggtcgg cggcgtccgc acggcccggg gcgaggcggt ccgggccgac atcgtgatcg
     5761 tcaacgccga cgcggcggcc ctgtacgggc ggctcctgcc cgaccgcgcc cggcttcgcc
     5821 ggatcgccgg gctgggcctg tcgtcgtccg ccttcctgct gctcgccgcg gtggaggggc
     5881 ggaccgaggg catgccgcac cactcggtgg tgttctccgc cgactaccgg cgcgagttcg
     5941 gcgacatctt cgaccggcgg cggccgccgg aggaccccac ggtgtacatc gcctgcccgg
     6001 tggcggacga ccccacccag gctcccgcgg gcgcggagag ctggagcatg ctggtgaacg
     6061 ttcccgccgg cgaccccgcg cgctggccgc tgccgcccga ggcgtacgcg gagctcgtcc
     6121 tcggccgtct ggcgagcagg ggccacgacc tgtccggacg gctgcgcttc ctcgacctgc
     6181 tgaccccggc cgacctgcgc gaccggtacg gcgcgtgggg cggggcgatc tacggcggcg
     6241 cctacggcgg cccgctggcc cccttccgcc gtcccggcaa ccgggggccg ctgcgcggcc
     6301 tgtacctcgt cggggggtcc gcgcatccgg gaggcgggct gccgctggtg gcgatgggcg
     6361 gccggatcgt ggccgcgctg gtgcgccgcg acttccccag ctccgcacgt cgcccgggga
     6421 aggcacaccc gtgagaacca gcgcggccag gacggtcggg tgcactcggg ccggacgggc
     6481 cggttgggcc gggaccgccg cgcgggtgct cgccgccgcc caggccgtgg cggccctcgt
     6541 cgtggtggcg cggctcgccc gcggccgccg gcggctcccg ccgctcaccg cgcccctgcc
     6601 ggacccgcct cccggcgccg gcggcccgcc tggtggcggg tgtccgggca tctcggtggt
     6661 catccccgcc agggacgagg agcggaggct cgggccctgc ctgcgggcgg tgctggccga
     6721 ccccgccgtc accgaggtca tcgtggtgga cgacgagtcc tcggacggca ccgcgcggat
     6781 cgccgccgcc tgcggggcga cggtggtgcg cggacgcccg ctgccggacg gctgggtggg
     6841 caagcagtgg gcgctgcacc aggggctgtc ggaggcgcgc ggcgagatcg tggtcaccct
     6901 ggacgccgac acccggcccc ggccgggcct gttcggcgcg ctcgccgccg ccctccggga
     6961 ccacgacctg gtcagcgcgg gcccccgttt cgtctgcgag ggactcgccg agcaggcgct
     7021 gcacgcgtcg ttcctcacca cgctggtcta caggttcggc cccatcggtc ctcccgcccc
     7081 gccgccgccc caccgcgtgg tggccaacgg ccagtgcctg gccttccggc gggaggcgat
     7141 gcggcgggcc gacggcttcg cccgggtgcg cgggcacatg accgacgacg tcgccctcgc
     7201 cagagccctc gccgcctgcg gctggagggt cggcttcctc gacgcggggg gcctgctgga
     7261 ggtcgatatg cacgagtcgg cggccgacgt gtggcgggag tgggggcgct cgctgccgct
     7321 gcgcgacgtc acccgccccg cctggcaggc ggccgacctc gccgtcgtct ggctcaccgc
     7381 cgcgttgccg gcgctccgcc tggccgccgg gcggccgacc cggctcgacc tggcgctgct
     7441 cgccgtacgg gtgctgctca ccaccgcgct gcggcgcagc tacgcccggc cgggcgcggg
     7501 cgtggcgctg tcgttcctgc tcgacccggc cacggccgta cggctgacgc aggcgacgct
     7561 gcggcccgtc aggacctggc ggagccgcgc ctaccccgtc taccccgcgg cgggggccgg
     7621 cgccgtcagg cgcggcgcgc ggccagcgcc gcctgcccga agcgcagccc gatgaggcac
     7681 atgagcgcgc cggtcgcggc gacgtggccg atcggcgcga acggcagttg cagcagcggg
     7741 atcgcgaaca ccccggcccg ggccccggcc gcgaacgacc gggtgagcag gaagaccacc
     7801 ccgagaacgg cgagcgcgag cccgaacgcg ggcgggcaga tcaccgcgat gccgccggcg
     7861 aaggtcagca ccgaccgccc gccgcggaac ccggcgaaga ccggccaggc gtgcccgatc
     7921 atcgccgccc ccaccgccag gtacgccgtg gggacgctcg ggcccgcgac cacccccggc
     7981 ccggtggtgt gggcgccgcc ggccagcagg ccgagcagcc cggcgagcac gcccttggcc
     8041 atgtccccgg cgaagaccgg cgccgccgtc cggccgccga gccgttcgcg cacgttccag
     8101 aagccggggt tgcggtcgcc gatctcccgg ggatcgacgc cccgccgccc cgcgaccagc
     8161 accgcgaccg gaaccgagcc gagaaggtaa ccgccgatga gcgccaccag cagggggatg
     8221 agcggcggga gcgtcgtcac gttccacctc cagcgatacg cggaccgggg ggccatgcgt
     8281 cacatggcct tcgaccgccc ggtgctgcgc cgcaccgggg ggctgctgtt ctggcggctg
     8341 ctcggctcgg gccggggagc gtcgacgacc ctcggcgccg acctgcgccg ctgggcgctg
     8401 ctcgccgtct ggcgggacga gcgggcgctc gaggagttcc tggcacgctc gccgatcccc
     8461 gccaggtggc ggcgcgaggc cgtcgaggcc tggcacgtac ggctcgcgcc gatcgcctcg
     8521 cgcgggcgct ggaacggggt cgagccgttc acacccgtgt cccggctgcc cgggccgccc
     8581 ggccgcgcgg ggtcccacgc cacggcgggg ccggaggacg gccccgtggc ggtgctgacc
     8641 cgggcgtcga tccggccgtc gcgcctggtc gcgttctacc ggtccgtgcc cgccgtcgag
     8701 cggtggctgc gggcccagga gggctgcctc gcctccgtcg ggctggggga gtggccgctg
     8761 gcccggcagg ccaccttctc cctgtggcgc gacgccgccg ccgtccgcgc gttcgcctac
     8821 gccgggcggg cccaccgcga ggttgtcgaa cgggtccgcg cccacgactg gtactccgag
     8881 gagctgttcg cccggttcat tccctatgcg agcgtgggca cctggggcgg cgccgacccc
     8941 ctcgccggtc gtcgaaccgc acagtgaacc gcacagtgaa ccgccccggt ctcctcgtgg
     9001 gccggggcgg cgcccggccg agcgggaggt cacggcgccg gctggacggc gagacggtcg
     9061 ccgagccggg ccacgacctc gccctcggcg aggtcgcgcg ccaccacgca ggcccgggcg
     9121 acggtgccgg cccgggagga gccgtgcgcc acgacgacgg tgccggtgag cccgaggagg
     9181 gccgcgccgc cgtgcgtctc ggggtcgtag cgggccgcca cccggcggag gccggccggg
     9241 ccggccacgc cctccgccgc cgcgagggcg agcgtggcgc gcacggtccc ctccacgttc
     9301 ttcagcacga cgttgccggt gaacccgtcg gtgacgatca cgtcgacgac cccggtgagc
     9361 acgtcgccgc cctccacgtt gccgtggaaa cgcagcggca ggccgcgcag cagggtctcg
     9421 gcccggcggg tcagccggtt ccccttgccg ggctccgcgc cgatcgacag cagcccgacg
     9481 cgagggtcgg ccacgcccag cacgagctgc gcgtacgacg ccccgagcag tgcgaactgg
     9541 gcgatcatct cgggcatcgg gtccacggtc gcgccggcgt cgaccagcac ggtgaccccg
     9601 cccgccgtgg tcgggagcgc gacggccagc gcggggcgca gcacggcggg cgcggtgccg
     9661 agccggtcgg ccgcgcaggc gaccacggcc ccggtggacc ccgccgacac gaatgccgcg
     9721 ccggctccct cccgcaggag gtcgaagccg acggacaggc tggagcggac catgcggacc
     9781 gcgcccgcgc cccgctcggt catcggcacg acctcggcgg cgtgcacgac gtcgatctcg
     9841 cccgccgccc cgagccgggc cagttccccg cgtacgaccc cggcccggcc gacgaggacg
     9901 accggcacgc cgtgctcccg ccacgcctcg accgcccccc ggacgatctc cgcgggcccg
     9961 tggtcgccgc ccatggcgtc caccacgacc gggcgggaca tcacgccacc tccacccggc
    10021 gttcggcgcg ggcggcggca cgcgcggcga acaggtgccg ggtgaagatc gcgagcctgc
    10081 gccgccggga gaccctggcc cgcctcgcca gcacgtcgtg cccggccgcc ccgatctcgt
    10141 ccaggatgcc gccgtacagc tcgtacgccg ccctgatgca gggccgggac gacggcgcga
    10201 gcagcgcgat cccgtcgcgg gcccgccggt agtggtcgcg ggcgcggtcg cactcgtagg
    10261 ccaccagctc ccgcacggcc ggcgcggcgt acggcgcggc caggtcggcc tccgtcacgc
    10321 cgaacttgtc gaggtcggcg agcggcaggt agacgcgacc ccgcgtcagg tcctcgcgca
    10381 cgtcgcggat gaagttggtg agctggaagg ccagcccgag ctggcgggcg ggctcgcggg
    10441 cccgcccctc ctcgcccggc agggcctcca gcaccggcag catcatcgtc ccgatgaccg
    10501 ccgccgaccc ttccatgtat cccagcaggt cgtcgtaggt cgcgtaccgg tccacggtga
    10561 ggtcggcgcg catggacgcg aggaacgccc gcacgtcggc ctggtcgatc ccgaacgccc
    10621 gcaccgtgtg cgtgaacgcg gggagcaccg gatcgcggac gtgctcgccg tccagcgcgg
    10681 cggcgagccg ggaggacagg cgctccagcg ccgcggcccg gtcgccggtc accgcgaacg
    10741 agtccacgat ctcgtcggcg tagcgggcga agccgtacaa cgcgtggacg tgcggccgtt
    10801 tccacgcggg cagcaggcgg gtggccaggt agtacgagcg gccgtagctc gcgtgcagcc
    10861 tgcggcaccg ctcgtagccg gccgtcagcg tcgcggccgg cgtctgtggt ggcgcgctca
    10921 tggggtgctc tccaggatgc gttcggcggc caggcggccg gagatcagca cgggcggcac
    10981 cccgacgccg ggcgccgtgt acatgcccgc gaagtggagg ccggggaccc gccgggccgc
    11041 gccggacggg cggaaccacg ccgtctgggt gaaacgggcg tcgagcgcga agggcgtgcc
    11101 ggccgagtgg ccgcgccgcc gccacgcggg gggatcgaac accagccggg gcgtgccgga
    11161 caggtcgccg tacccgaggc cggcgagccg gcccagcatg cggtccacga ggcggggggt
    11221 gagcgcggtc cagtcggcgc cgccccgcgt gttgggggcg ggctccagca cgctgagcac
    11281 ggcgggcccc ccgccgccgg gcccgtggtc gccgggcccg tggtcgtcag ggccaggaca
    11341 ggtcacgagc aggctcgggt ccggctgcgg cctgcccgcc tccagctccg cgaacgtcgt
    11401 ctcccattca cgcccgaagt gcagggtgtg gtgggcctgg ccgtccgggc gccggtccag
    11461 cgcgaagtgc gcgaccaggc acgaggggga caaccggggc cggcgcagcc gccagtcggc
    11521 cgcctcctcg ggcagcaggc cgtcgccgtc ccgccgcccg tgggcccgga gcaggtcgca
    11581 ggccaccacg gcgtgccggg ccgccagccg ctccccggtg tcgaggcgga cggcgaccac
    11641 ccccgccccg tcggtctcga tccgcgtggc ccgcacgccg tagcggaaga cggccccggc
    11701 cttctcggcg gcggcggcca tggcccgcgg gacggcgtgc atgccgccct cacgggggaa
    11761 gtagaccccg ccgaccgtgt ccatgtgggc gatcacggcg tacacgccga gggcgcggcg
    11821 cggcgacagg ccgacgtaca gcgcctggaa cgtgtgcgcc ctgatcaacc gctcgtcggt
    11881 gaggtggcgc cgcacgagcc cgtccagccg gcggaagccg ccgagcgcgg ccagccgcac
    11941 cagcgcgtac ggccgggcca gcgcgcgcag ccgggtcatg tcgcggtcga tgaacgcgct
    12001 ccactcggcc tcgaacatct cgcccagcaa ctgccggaac cgccggtagc gcacggcctc
    12061 ggcgggcccg cacagcgccc gcacccgctc ggccatggcg tcggcccccg ccaccacgtc
    12121 cagccgcgac ccgtcgtgga aggtcagccg gtagtacgga tcgagccggc gcagcggcag
    12181 ccagcgctcc aggtcctgcc cggcggcggc gaaggtgtcg gccagcaccc ccggcatggt
    12241 cagcaccgag ggcccgatgt cgacccggtg ggagcccagg gccgccgtgc cgcagcagcc
    12301 gcccggcacg tcggcggctt ccacgaccgt cacctcgcgg cccgccccgg ccaggcgcat
    12361 cgcggcggcc aggccgccca gcccggcgcc gacgaccacg accggcccgc ccgcggtcat
    12421 cggcgggctc cgccggtcga gggccccgcg gattcggaca ggggagcggg gccgggtcga
    12481 gcggggtcgg gttgagctcg gcaggtgcgg gcgaggaggc ctgtgggatc ggggtgggtg
    12541 aggcggcggg cgaggtcgag cagggccgac cgggcgtccg cgggcatgtc cgccccggac
    12601 agcgccccgg ccgcggcctc cgtcaggtcg ccgatgcgcc gctcgaccgt ctccagcgcg
    12661 ccggtcgcga cgatcacctc ccgggccgcc gccacgaggt ccggcggcgc ctcgccaggt
    12721 ttcggcagcg cgtccggccg cgcctcgccc ggcctcggca gcgcgtccag cagcgccgcg
    12781 cccgggccgt ccgcccgttc gcgggccagc gccagcaggt aggtccgctt gccctgcagc
    12841 aggtcggccc cggcgggctt gccggtccgc gccgggtcgc cgaagacgcc gaggacgtcg
    12901 tcgcggagct ggaaggcctc gcccagcggc agcgcgtacg cgctgaggac ccggcgcaac
    12961 ccgggctcgc ccccggcgat ggcgtgaccg aggtgcagcg gccgctcaac cgtgtatttg
    13021 cccgacttgt acgtcgagat cagcagggcc tcccggcgcc cgcccccgcc ccgggcggcg
    13081 caggtcaggt cgaggtactg cccggcggcc agttcgacgc gcagctgggt gagaacctcc
    13141 agggcatcgg ccagcctgcg gcggtcggcc agcagtgcgg aatcggccca ggtgaaggcc
    13201 agcatgccga gcaggacggc ggccgactcc ccgaaccgcc gcgacgaccc ggcccagccg
    13261 ccctcccgat gccgctcggc gagcgccacg tgggcggtga cccggccgcg ccgcagcggc
    13321 gactcgtcca tcacgtcgtc gaggatcagc gcgcacgcgt ggaggagctc gatcgagcag
    13381 ccggccgcca gcacggcgtc gaggtcgtcg ggggagccgc cggaggcccg gtggccccag
    13441 taaacgaaag ccggccgcag ccgcctgcca ccgcgcgcga cgaagccggc gaggtggcgc
    13501 cgcaacgtct cccggtcctc ggccccgagg aaggacagcc ggtccatctc acgccggagc
    13561 agctcgtcca gggcccggtc gaagagggtg cggtcgaacg acagggtgcg gtcgaacagg
    13621 gcgccgtcgg acgggccgga caggtgatga tcggacggct cccgcgtctc gtcccgaacg
    13681 ccgccggtct cgcgggtcaa cgtcaccatg cgcactgctc cttcgatcgt tacggtgatc
    13741 ggcggcgccg tcagtagagt tttcgcgccc gcccgctccg gcggttgcat ccgtgccggg
    13801 ctcccccgtc gaaacaaggc cagggggcgg ccgaaagggg cggaggcggc cacgaggacc
    13861 gtgcgcgtgc ggctcccggt gtgccgtgcc cggccgtggt cgtgcccggt gctcgcgagg
    13921 cgcgcgccgg cgggctgaga ggctggtcgc agggacgcgt acgggcggcc ggagcacggc
    13981 gagtggccgg gacgaccggc cggacggaca cggggtgagc gggtggcaga cgaggacgca
    14041 ccgggggccg gcgagaacgc ggccgccgag gaggagccgg gctacggcat cggggccgtc
    14101 tcccggcggc tcggcgtgcc cgcgtccacg ctgcgcacct ggaacctcag gtacggcatc
    14161 ggcccgagca ggcgcagccc cggcgggcat cgccgttacg acgacgcgga cctgcgccgc
    14221 ctggaggaga tgaaccggct gatccgggcc gggatgccgc cggccgacgc cgccaggcag
    14281 gcgctgcggc cgcggtccgc accgggagag cgggcggcgc ccccggccgg gccgggcgcc
    14341 gccgcgcccc cggagtcccg tgcggggtcg tccgcgccct ccgagtctca tgagtccccg
    14401 gagccgcgcg tggcgcccgc gcccgccgta cggcaggccc cggaacccgg gctgctgtcg
    14461 gcggtgatgc tggcccgcgc ggtgacggcg ctggacgccc cgaccgtgag cgtgggactg
    14521 gacacggcgc tgaccacgca cggcgtggtg tggacgtggg agcggctcgt gctgccggtg
    14581 ttcgcggccg tcagccgcag gcagcaggac acgtgcgccg ggatcgacgt cgagcacctg
    14641 ttctccgagc ggctccaggt cgcgctcgcg cggttcgccg cccgtgcgcc cgcgcccgtg
    14701 catccccgtc cggtcctgct ggccgccgcc gaggaggagc agcacgcgct gccggtccac
    14761 gccctggccg cggcgctcgg cacgctcggg gtggagaccc gcgtgctcgg ggcgcgcacg
    14821 ccgtaccggg cgctggcgga cgcgatgcgc cgcctcggtc ccgcggcggt gttcgtgtgg
    14881 tcgcagatgc gggagaccgg cgatccggcg ccgctggccg atctgccgcg gctccgcccc
    14941 gcctgccgcg tcgtggccgg cgggcccggg tggggggacc acctgcccgc ggaggtcgtc
    15001 cgggtgacga cgtttcgcga cgccatctcg gcggtaatga ccactctgcg gtgaattcgc
    15061 gctctttggc actttttgaa gccagagttc ggccccccat ggttgccctc ttccggcgcg
    15121 ggcagctatg aataggtttt gaataagttt tggggtcaag gggggccgat ggaggagacg
    15181 ctggagttcc gcctcgccgc gggagacgcg ggcgccctgg gggagtgcta ccgcgcccac
    15241 tcgccggccg tgcgctccta cctgcgcaga ctcgtgccgc cccaggacgt cgaggacgtc
    15301 ctgcaggtcg tcttcaccga ggtgtggcgc ttccggcacc gcttcgaccc gggtcgcagc
    15361 ctgtcggcct ggctgttcgg catcgcgcgc aaccgcgcgg tggaccacct gcgggcgcgc
    15421 acgcccacga cggtgccgct ggaggcggtg cccgacccgg cggggcacga cggccggctg
    15481 gacggcgacg agctcgccga ccgcgaccgc gtccggcgcg cgctggccgc cctgccccat
    15541 gtgcagcgcc aggcgatcga gctggcgtac tacggggacc tgacccagcg ggagatcgcc
    15601 gagcacctgc gcgtcccgct cggcacggtc aaggcgcgta cggcgcgcgg cctgcaccgc
    15661 ctgtccacgc tgctgcggac ggcggcctga ccatggaacc ggcggaggag atcaggccca
    15721 gggtggccgt gtcgagctgc ctgctcggcg ctcccgtacg gttcaacggc ggccacagcc
    15781 gtgaccggtt cctgaccggc gatctgtcgg agtacgtgaa ctgggtgccg gtctgccccg
    15841 agatcgagat cggcctcggc gccccgcgtg agacgctccg cctggagcgc tccgcgcaag
    15901 gggcacgact gatgacccga cggacgcgcg aggacctgac cgccccgatg accgccctcg
    15961 ccgccgagcg cgcggccggt ctgggcgacg tcgacgggta cgtgttcaag tcgaggagcc
    16021 cgagctgcgg gctccacggg atccccgtgt acgcgggaga gagcgggccg gccgaccggc
    16081 gcggcagggg gatcttcgcc gccgcgatcg ccggcgcccg gccggagctg gcggtcgagg
    16141 acgagggccg gctgcacgac gccgtgctgc gcgaggcgtt cgtcgagcgg atcttcgcct
    16201 cggcccgtct gcgggccctg ctggccggcg actggcaccc ccgtgacctg gtcgccttcc
    16261 acgcccggca caagatgcag atcctcgccc acgcgcccgc ggcgtaccgg gagatagggc
    16321 ggctcgtggc ggcggcgggc gagcggccca gggacgcgct cgcgggggag tacgcccggg
    16381 cgttccggac ggccctcgcc gcccgggcca cggtcgggcg ccacgtcaac gtcctgcacc
    16441 actgcctcgg catgatcggc cgggagctcg acccggtccg ccgggccgac ctggccgagg
    16501 tgatcgcgtc gtaccgggcc cgcagggtcg ccctgacggt gccgctcgcc ctgctccggc
    16561 accacgcgag gggggcgggg gtcgattacg tccgcgacca gacctacctg tccccctatc
    16621 ccgacgcgct gcgcctgcgc aaccacgtcc ccgcatgaac gcgccccgcg gggcaggaga
    16681 ggacccatga gatccacatc gacgaagacg ctgctgcgca cggccctcgc cgtgaccgcc
    16741 gccgccgcgg tcggcggcct gtccaccgac gcccgctccg gctggtaccg ccggctgcga
    16801 aagccctcat ggcagccgcc gccgcaggcg ttcggcctgg tctggacgcc gttgtacgcg
    16861 acgatcgcct acgcgtccgc ccgcgcgctg tcgcgggccg gcgacggctc ccggccggcc
    16921 ctgcggcggg cgctcgccgt gaacctggcg ctcaacgcgg cctggccgcc gctgttcttc
    16981 aaggcgcgca acccccgcct cgcgctcgcg gagatcctcg ccctcgacgt gtcgaacgcg
    17041 ctgttgaccc gccgcctcct gcgcgaggac cgcacggccg ggctcctgct gctgccgtac
    17101 gccgggtgga cggtcttcgc caccgcactc aacgccgcca tcgcccggca caacccgcag
    17161 gcgcggcgcg accccggcgc ccaaggagcc tgaggagcct gaggatcagc cgaccgcgcg
    17221 gcggaaccgc tcgccgagcg gcgcgtcggg gacggtgggc ccgcgcgggt tcacacggtg
    17281 gcgacccgcg aggcgggcgg cgccttcacc gtgatccggg caccccagcg agcgtagtac
    17341 gtgtcggtcc actcaccgcc gccggccacg cccttgcggc tgtcgctcct ccgcgaccac
    17401 tgcgtggtca gccgcactac ccggcccttg ccgtccagcc acaggctcca gccgatcttc
    17461 accgggctcg acttgccgaa ggcctcccgg cacgccgccg acaccgtgca cagggccttc
    17521 gcggtgacgg tgccgctgta gcgcgtggcc gggacgccat tgacgctctg gtgcaccgcc
    17581 ccgccgctcc gggtggcgta caccgcgcgc agcgtcgcgg gttcgaagac gtcgatcgcc
    17641 tggccggacg cttggtacgg ctcgagacgg aggtcccggc tgcgtaccca gctcttgccc
    17701 gcgggcaggc tgtccgacca gagcccgccc tgggcgtagg ttctgccgcc tacgatgagg
    17761 aacctgaacg tcttcccgga cgtggtcacc cgcttgacgg acgcggccgc gagccttccc
    17821 ctgccgaaag cgagaacgcc gctgttccgg aagaccgtcg cgtccgatcg gtcgtcgccg
    17881 atccaggatt tcgaggtctc ggtgaacgcc actccgcgtc cctggaccag cgccttgctc
    17941 atgacggccg cagggccggg tgttcccgcg ctcgcctgcg ccgtggggac gagaaccgcg
    18001 gttcccgcga cagcgatggc caggcagacg cgggtacatg acattgaggg gcccctttca
    18061 cgcaatgtcc aaaaatcttg gtcttcatcg catggtcgcg caagcgcttt ccgggcgcct
    18121 tcgggactgg gcgggcggcg gcacgacgcc cgggcgagca gcgacgccgg gtggggacct
    18181 cggggtgaac ggctctggcg aacccccgtc aggggtcgtt cactgggctg cggtgtcgag
    18241 ttcgcgcgga agctcggact cgtcggcccg gtgttcgaag gccgcgagga tcgtggcgag
    18301 gatctcgcgg aactgccgta cctgaccggg ggtgaggggg tcgaacagca cccgccggac
    18361 ctcgtcgacg tggcccggcg ccgccttcac gatcgcggcg aagccctcgt ccgtgagctc
    18421 ggcgacggtc gtgcgccggt cctccggccg cttgagccgc cgcacccagc ccttctcctc
    18481 cagccgggag acggcgtggg acaggcggct gaccgaatac tggaggatgg cggacagttc
    18541 cgtcatcgtc atggtccgcc cgggagactc ggagaggacc accaggatca tgtagtaggc
    18601 gtgcggcatg ctcgagtcgc gctgcaactg ccgttcgaga gcctcctgga ggagctggct
    18661 cgtccgcagg tatgcgcgcc aggtgcgctg ctcctcctcg tcgagccatc gggtgccggg
    18721 catggcgcca agactaccgc cgtgagcagc ttgatcttgg ggcgaaagac cctggttcgg
    18781 ccgccgccgt tgggaaagtg tcatgggcat gaacgcatac gggaacatcg acgcctactg
    18841 gcgggccgcg aattatctgt ccgtcggcca gatctacctg atggacaacc cgctgctgac
    18901 cgagccgctc aggcccgagc acgtcaagcc gcgactgctc ggccactggg ggaccacccc
    18961 cgggctcaac ttctgcttcg cccacctcaa ccggatcatc cgggagcggg gccaggacat
    19021 gatctacatc gccggccccg gtcacggcgg cccggcggcg gtcgcccacg cgtggctcga
    19081 aggcacctac accgagcgct acccccacat cacgcgggac gccgagggca tgcgccggct
    19141 cttccggcag ttctccttcc cgggcggcat ccccagccac gtcgcccccg agactccggg
    19201 ctccatccac gagggcggcg agctcggcta cgccctctcc cacgcgtacg gcgcggcctt
    19261 cgacaatccc ggcctggtcg tggcctgcgt cgtcggcgac ggcgaggccg agaccggccc
    19321 gctcgccacc gcatggcact ccaacaagtt cctcaaccgg gacaccgacg gggtggtcct
    19381 gccgatcctg cacctgaacg ggtacaagat cgcgaacccg accgtgctgg ccaggatccc
    19441 cgaggaggag ctggtcaagc tcttcgaggg gtacggctac cgcccgcaca tcgtctccgg
    19501 ccacgaaccg gccgagatgc acgagctgat ggccggcacc ctcgacacgg tcttcggcca
    19561 gatggccgac ggcggcccgc tgccgatgat catcctgcgt acgccgaagg gctggaccgg
    19621 gccgcgcgag gtcgacgggc tcccggtcga gggcacctgg cgcgcccacc aggtgccgct
    19681 gaccgacgta cgggaccggc cggaccggct ggagtacctg gaggagtgga tgcgctccta
    19741 ccgcccggag gagctgttcg acgccgacgg gcggccggtc gagacgatca cggggaccgt
    19801 ccctgacggg ccgctgcgga tgagcgccag cccgcacgcc aacggcgggg aactgctgcg
    19861 cccgctcgtg ctgcccgact tccgcgacta cgcggtcgag gtgaaggccc cggcgacggc
    19921 ctccagcgag ccgacccgcg tcctcggggc gttcctgcgc gacgtcatcg cggccaaccc
    19981 tgcgaacttc cggctgctcg gcccggacga gaccgcctcc aaccgcctgt cggccgtctt
    20041 cgaggcgacc ggaaaggagt gggaggccgc cctgctgccg accgacgaga acctcggccc
    20101 cgggggcagg gtcatggagg tgctcagcga gcaccagtgc cagggctggc tggagggcta
    20161 cctgctgacc ggccgccacg ggctgttcaa ctgctacgag gccttcatcc acatcgtcga
    20221 cgcgatgttc aaccagcacg ccaaatggct ggagtcctcc cgcaagattc cctggcggcg
    20281 gccggtcgcc tcgctgaact acctgctgtc gtcccacgtg tggcgccagg accacaacgg
    20341 cttcagccac caggaccccg gcttcctcga cgtcgtcgtc aacaagaagg ccgaggtcgt
    20401 gcgcgtctac ctgccgccgg acgccaacac cctgctgtcg gtcgccgacc actgcctgcg
    20461 ctcgcgcgac tacgtcaacg tcgtcgtggc gggcaagcag cccgtgctcg acctgatgag
    20521 catggacgag gcggtcgtcc actgcacccg cggcctgggc atcctcgact gggcctccac
    20581 cgacgagggc gccgaccccg acgtcgtgct cgcctgcgcc ggcgacgtgc ccacgctgga
    20641 gaccctggcc gccgccgcgc tgctccgcga gcacctgccc gagctgcgga tccgggtgat
    20701 caacgtggtc gacctcatgc ggctgcagcc ggcctccgag cacccgcacg gcctgcccga
    20761 cgtcgagttc gacgcgctgt tcaccacgga caagccgatc atcttcaact tccacggcta
    20821 cccgtggctg atccaccggc tcacctaccg gcgtacgggg cacgacaacc tgcacgtgcg
    20881 cggttacaag gaggagggca ccacgaccac gccgttcgac atggcgatgc tcaacgacat
    20941 cgaccgcttc cacctggtga tggacgtgat cgaccgggtg cccggcctgg gcagccgcgc
    21001 cgcccacctg cgccagcgca tggccgacgc ccggctgcgc gcccgcgccc acacccgcga
    21061 gttcggcgag gaccccgccg agatccgcga ctggacgtgg cccttctgag tccccgggcc
    21121 cggttaatcc cggcacctct cgctccgggg cggggacccg ggcgcggcgc atctccgcca
    21181 ttcgggggcg gcggcaccgg tagcatcgga ggcgaccgga gccgccgcct cgcgtgcgcg
    21241 cggccaccga gatccacgca tcgaacctgt cctaaggagc caccgtgtcc gccgcccttg
    21301 agatacgcat caccctcgcc ggagccgagc gcgtggtggc ggcgggtacg acggccgggg
    21361 aggcgctcgg cgccgacggc aggtcggtga tcgccgcccg gatcaacggg gagccgcgcg
    21421 acctggccgc cgaggtcgcc gagggcgacg tggtcgagcc ggtcgagatc gacagccccg
    21481 acggccgggc gatcctgcgc cactccaccg cgcacgtcat ggcccaggcc gtccaggaga
    21541 tcttccccga ggcgaagctc ggcatcggcc cgccggtcga gaacggcttc tactacgact
    21601 tcgacgtccg cgagccgttc acccccgacg acctcaagcg catcgagaag cgcatgcgcg
    21661 agatcgtcaa gcaggggcag agcttccggc gccgcccggt cggcgacgac gaggcccggg
    21721 ccgagctggc ggccgagccg tacaagctgg agctcatcgg gctcaagggc ggcgcggccg
    21781 aggcggccga cggcgcgaac gtcgaggtcg gcggcggcca gctcaccatc tacgacaacc
    21841 tcgaccccaa gtcgggcgag ctgtgctgga aggacctgtg ccgggggccg cacctgccga
    21901 ccacccgggt catcccggcc ttcaagctca tgcggtcggg cggcgcctac tggcggggca
    21961 gcgagaagaa cccgcagctg cagcgcatct acggcaccgc ttgggagtcc cgcgagaagc
    22021 aggacgagta cctcaagttc ctggaggagg ccgagaagcg cgaccatcgc aagctcggcg
    22081 ccgagctcga cctgttctcc ttcccggacg agctgggctc cggcctgccg gtgttccacc
    22141 cgaagggcgg cgtgatccgc cgggtgatgg aggactactc ccgccgcagg cacgaggagg
    22201 cgggctactc cttcgtcaac accccgcaca tcacgaagga caacctctac aagatctccg
    22261 gccacctcga ctggtacgcc gacggcatgt tcccgcccat ggagctggag ggcgcgcgct
    22321 actacctcaa gccgatgaac tgcccgatgc acaacctgat cttcagggcg cgcgggcggt
    22381 cctaccgtga gctgccgctg cggctgttcg agttcggcac ggtctaccgc tacgagaagt
    22441 cgggcgtggt gcacggcctg acccgcgtac gcggcctgac ccaggacgac gcgcacatct
    22501 actgcacccg cgagcagatg cgcgacgagc tcacctcgct gctgcggttc gtgctcgacc
    22561 tgctgcgcga ctacggcctg gaggacttct acctggagct ttccaccaag gatccggaga
    22621 agttcgtcgg cagcgacgag acctgggagg aggccaccca gaccctgcgg gaggtggccg
    22681 agtcggagaa gctggagctg gtcctcgacc cgggcggcgc ggccttctac gggcccaaga
    22741 tctcggtgca ggcccgggac gcgatcggcc ggtcctggca gatgtcgacc atccagctcg
    22801 acttcaacct gcccgagcgc ttcggcctag agtaccaggc tgccgacggc acccggcagc
    22861 ggccggtcat gatccaccgg gcgctgttcg gatcgatcga gcgcttcttc ggcgtgctgg
    22921 tcgagcacta cgcgggcgcc ttccccgcgt ggctcgcccc ggtgcaggtc gtcggcatcc
    22981 cgatcgccga cgcccacgcg ccctacctgc aggacgtcgc caagcggctg cgtgagcagg
    23041 gcatcaggat cgaggtcgac gagagcgacg accgtatgca gaagaagatc cgcaacgccc
    23101 agaaggccaa ggtgccgtac atgctgctgg cgggcgacga cgacatcgcc gccggtgcgg
    23161 tgtccttccg ctaccgcaac ggcgagcaga agaacggcgt gccgatcgac caggcgatcg
    23221 acgagatcgt cgacgccgtc cgccgccgca tccaggtctg acgggcggaa gacagcggat
    23281 cgggcgtccc ctccggggcg cccgatctcg catgaccggc ccagtgccgt ctcaggaggc
    23341 cggcgccgcc tcggcggggg agccctgacc ggggaggcgg acgtcgtcca cggtcacgtt
    23401 gacctcgacc acgcgcatgc cgagcatgcg gcccaccgac cgggcgacgt tgaccttgac
    23461 ctcggtggcg acgtccatga ccacatggcc gtacacgatg acgatggtca cgtcgacgga
    23521 gacctgctca tcctggatct tcgcctgcac gccctgcgtc gcccgcttgg cccccacgcc
    23581 gatgaggtcg cgtacgttct cgaaggcgcg ctcgaggtcg ccgcccaggt cggcgacgcc
    23641 ggggatctcc agtgcggcca gggcggcgac cttctccacc acctcgtcgg cgaccttgat
    23701 gcggccctt
//
