LOCUS       NZ_JABBXA010000002     21101 bp    DNA     linear   CON 07-NOV-2024
DEFINITION  Microbispora sp. H13382 NODE_2, whole genome shotgun sequence.
ACCESSION   NZ_JABBXA010000002
VERSION     NZ_JABBXA010000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora sp. H13382
  ORGANISM  Microbispora sp. H13382
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 798438)
  AUTHORS   Liu,C.
  TITLE     Selective isolation, identification and anti-microbial activity
            study of Microbispora
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 798438)
  AUTHORS   Liu,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-APR-2020) Microbiological Resources Collection Center,
            Sichuan Industrial Institute of Antibiotics, 168 Huaguan Road,
            Chengdu, Sichuan 610052, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014161445.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 07:22:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,982
            CDSs (total)                      :: 7,906
            Genes (coding)                    :: 7,786
            CDSs (with protein)               :: 7,786
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 21 of 121
            Pseudo Genes (incomplete)         :: 104 of 121
            Pseudo Genes (internal stop)      :: 8 of 121
            Pseudo Genes (multiple problems)  :: 11 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:45:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 647586
            Orig. end                         :: 668687
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABBXA010000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21101
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="3"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21101
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21101
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11101](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11101)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    1155..1175
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.24"
                     /tool="antismash"
     gene            1327..2895
                     /locus_tag="HHX41_RS06930"
     CDS             1327..2895
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009072637.1"
                     /locus_tag="HHX41_RS06930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_220503765.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.4e-16, bitscore:
                     56.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDNILDYLVVGAGPAGLQMGHFLHRAGRAYRILEAAPEPGAFFR
                     TFPRHRTLISINKKHTGWDDPELNLRMDWNSLLSDDPRLLFTRYSDRYFPAAEDFVRYI
                     EDFVALQGLHVTYDARVAEVARPDAEGPFLATDEYGRTYRARRVIVATGVSRPNVPPIP
                     GIETAEQYSTHSTDPADYTDMRVLVIGKANSAFETADNLIETAAVVHVAGPHPVRLAWR
                     THFVGHLRAVNNNFLDTYQLKLQNAVLDGDVRRIERRADGSYLVTVAFVRADEVTKDIP
                     YDRVIVCTGFRFDASIFSPECRPDLAIGDRFPALTPAYESVNVPDLHFAGTITQSLDFK
                     RGTNGFIHGFRYGVRALHRMLENRHHGVPWPGRDLPADPDALAAAVLERVNRSSALWQQ
                     FGVLADVIVPDGLGGMRYLEELPIDLQGPPIGDAGHFAITLEYGPHHDQVDPFDLSVGR
                     IRQSDAERAHEGHYLHPVVRRYRGGVVEAVHHVTENLENDWTSDEVHLRPLRDFFTRQS
                     LPVSV"
     gene            2901..3944
                     /locus_tag="HHX41_RS06935"
     CDS             2901..3944
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013253.5"
                     /locus_tag="HHX41_RS06935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha-hydroxy acid oxidase"
                     /protein_id="WP_220503766.1"
                     /transl_table=11
                     /translation="MLTTIREFEAAARDRLDPAHYDYIAGGAGDEVTVKANEAAFARLA
                     LLPRVLRGAGSPRIGVTLLGSRAEMPVLVAPTAFHRLADPEGEKATARAAAAAGTIMIV
                     SMAATVAVEDVAAAAPGATLWFQLYVQPDMAFTEAIVRRAEAAGCAALVVTVDSPARGR
                     RDRDVRRGFDDLPEGMRCENLRDGDAESVRPIVMSPAISWEHVDSLRRMTRLPIVLKGV
                     THPADARLALDHGVAALYVSNHGGRQLDTVPATVDLLPEIVAVVGGAVPVLVDGGIRRG
                     TDVVKALALGASAVAVGRPVVWGLAADGECGVARVLGLLRDEVEHALTLCGLASPHDLE
                     PGLVRRC"
     gene            3938..5293
                     /locus_tag="HHX41_RS06940"
     CDS             3938..5293
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="HHX41_RS06940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_182905235.1"
                     /sec_met_domain="p450 (E-value: 1.4e-21, bitscore: 72.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTAVWVALWVAGAIVVISLPRWLPGRVVALRGWVFTRINGEESI
                     AVPGDLVGVDRFREIYSHPAASGRSEGAVLSDLFWYWLSPGPEMHQEHLEAGERYDAVA
                     LATRRILSLPRAQVEELTRRCVRRALEGGRGLVRLRDLMMPAWAEFSYELVFGEPCPPQ
                     VRDLIVGNADDVVTALKCCGLRHMDRRDRLTAYLVESLPRVRHELPAGLTPREQALYLH
                     GAFFTTAVVQMSEAMAHVLMALAQHPDVQDRARSGDDHYLDQVIAETLRLYPLFGIAHR
                     VTKGDIPLGEGVAIPAGSVLCFDYPAFHRSGFPDPERFDPGRFAPGHTPVRELNHIPFG
                     MPANRPCPAWRLAPLAMRVATREVLRAYALDTTAGHTRSLPNRGPCLLTPPAAGRGPGR
                     RLTLLSMRLRDGWEDVWRSLVQLVLGTYMVWDARRLRLCERHFTRDARPEGT"
     gene            5363..6685
                     /locus_tag="HHX41_RS06945"
     CDS             5363..6685
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013188.5"
                     /locus_tag="HHX41_RS06945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cation:proton antiporter"
                     /protein_id="WP_182905236.1"
                     /transl_table=11
                     /translation="MEAHTADPNLELALRVLPALAVILLAAALCGRLATLVMQPRVVGE
                     MVAGVLLGPTLLGALFPGAQAALFPAEVRPVLYVLSTLGLTLYMFLVGAGMDHDARAPG
                     ELRKASVLAASGIGSPLVLGGAAGLVLWDRLSRPDVGRIEFALFLGGALSLTAFPMLAR
                     ILYERGLQNTRIGRIALLAASIDDAVAWCLLAALSAAHLGGGPGDTLRTIALAGVFAAV
                     MLGVVAPLLRPLGRRVARTGRLGAGAVYVIVLVPLAAGWITDAIGVYSVFGGFVAGLSM
                     PREPAFRAALHDRMMDVVSTLLLPVFFAFSGLNTHLGGIAGGSALLAFALILTLAFCGK
                     YFGCSLATRALGFGWRESWAMGAMMNARGLMILIFINIGLAQGMITQELFAMLVLVAVL
                     TTAGALPLYKLALPERHERADAGSVGSAARMGAAAGETGFI"
     gene            6786..7475
                     /locus_tag="HHX41_RS06950"
     CDS             6786..7475
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="HHX41_RS06950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_220503767.1"
                     /transl_table=11
                     /translation="MARIPGTSEPRSRRLLLVEDDRELGDMLVEVFTDQGYTVDLALEG
                     QRGLHLALTRGYDAMVIDRGLPVVDGLDLLRRLRRQAVTVPVLMLTAFGALADRVTGLD
                     AGAEDYLVKPFEIDELLARVRALHRRNLDQATLLPLGAGWLDSASCVVRLPSGEQVTLS
                     GQECRLLHALAARPRQVHTRTSLRQRVFDGARTESIVDTYVYYLRTKLGPGVVRTVRGV
                     GYRLGEL"
     gene            7472..8842
                     /locus_tag="HHX41_RS06955"
     CDS             7472..8842
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="HHX41_RS06955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_182905237.1"
                     /transl_table=11
                     /translation="MKTTRSSDPERRLLILTRRRITAQVAAVFTLAITLLGTLVYCVVA
                     DAQDATARRDLAVAAMSAPMDHPPPCVWLFELRADTVRRSPGAPEGLPVRETLDRVAAD
                     GRTRVDVAEVGGHTYLVRTQRRGDVPLQAVMDLYYPVTERQRLLRTLCAAEVAALLVAL
                     LIGQVLARRAIAPLGEALDRQRRFTADVSHELRSPLTRLHVRAQLAARRLRREPDPLLV
                     VGDVDRLVTGIGQLGEVIEDLLLSTQLRQSRRPFGPADLAALAEEAADAEAARAGQRGV
                     TIDLRRDPGDHVVCGAPSALRRVISALLDNALRHTSTGGHIWVSVCSGPQTVQLSVRDD
                     GVGLDPRDGERLLVRHVGAPHTGGLGIGLALVSEVMNAHGGAIDVDGRPGAGATFTIRL
                     PRAAPDPAPHLSRIGLPAPAAAERDEQNAGGDRLRPRRRLPVVLRGWRSVLTRANAR"
     gene            complement(8820..9440)
                     /locus_tag="HHX41_RS06960"
     CDS             complement(8820..9440)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017599781.1"
                     /locus_tag="HHX41_RS06960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_310741806.1"
                     /transl_table=11
                     /translation="MDGTRRVRMDGEEARRRILDAAERLFYARGIQAVGMDQVRDAAGV
                     SLKRLYQCYASKDALVEAYLEHRDRRWNDALSDHLGSVGEPRERVLAVFGFLAEWFGTA
                     DFRGCAFVNAFGELGPASPPVVAAARAHKNALRGRLRTLTAEAGAADPDLLADQLLLLV
                     EGAIVAAAMGTAADPAERARSAARALLDAAAAPDHPLTAHWPS"
     misc_feature    complement(9461..9474)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.19"
                     /tool="antismash"
     misc_feature    complement(9490..9503)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.6"
                     /tool="antismash"
     gene            9527..9985
                     /locus_tag="HHX41_RS06965"
     CDS             9527..9985
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017619227.1"
                     /locus_tag="HHX41_RS06965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_182905238.1"
                     /transl_table=11
                     /translation="MSTRPPLPPFTEETARQKVQAAEDAWNTRDPERVALAYTEDSVWR
                     NRSEFLTGREEIVAFLRRKWEREQDYALRKDLWTFGGDRIAVRFQYEWQDADGRWWRSY
                     GNELWEFTAEGLMSRREASINDMPIEESERRIRGPRPESERGAGLPLA"
     gene            complement(10001..11101)
                     /locus_tag="HHX41_RS06970"
     CDS             complement(10001..11101)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013094.5"
                     /locus_tag="HHX41_RS06970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_220503768.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 3.2e-15,
                     bitscore: 51.6, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 1.9e-45, bitscore: 150.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAQHRPHRYGNDRIRIGGSVNGVTAEISDPDGHAWAALNAMDGT
                     RTPEEVVARLHRAFPGLTEAEAADVVDLLLSSGCVEDAAGPRPEELSLRELERYSRNAA
                     FFRDVDPTRPERGWEAQVRLKRSRVLVLGLGGTGSHTAWALAACGVGEIHCVDRDPVEL
                     PDLTRQALYRESDIGSPKVDVAAARLAEVNSSVRVTAEARPVECEEDMLDLVRGFDAVA
                     MCADEPAGRGGIRVWANRACLSEKIPWALGGYNGPLVSVAAFTPGGPCYECLTASVDAP
                     LAPGIPVDLGGPGAIAPSAGVSGHLTAQAVVAFLTGIPATSGSYVTGINLAAPDQHVYT
                     RHPGAPDCPACSPDALRAGSLGSMAR"
     aSDomain        complement(10847..11098)
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HHX41_RS06970_Pantocin_Microcin_RRE.1
                     "
                     /evalue="1.20E-16"
                     /identifier="RREFam017.1"
                     /label="HHX41_RS06970"
                     /locus_tag="HHX41_RS06970"
                     /protein_end="85"
                     /protein_start="1"
                     /score="51.6"
                     /tool="antismash"
                     /translation="KAQHRPHRYGNDRIRIGGSVNGVTAEISDPDGHAWAALNAMDGTR
                     TPEEVVARLHRAFPGLTEAEAADVVDLLLSSGCVEDAAG"
     misc_feature    11161..11175
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.09"
                     /tool="antismash"
     gene            11246..11749
                     /locus_tag="HHX41_RS06975"
     CDS             11246..11749
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012886836.1"
                     /locus_tag="HHX41_RS06975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_182905240.1"
                     /transl_table=11
                     /translation="MTERSPDGATVWARNSRLRVVPPVQPRKLAKVPFVELADGRLQGV
                     VSSGSDIGRVYVSSIAAGTHNYNCSTNNNRPCGGLYGAPCKHLRALVAEAVLQYGADRV
                     SRYLRAEVPEGAELADCLRGIHEPAPAAVVFSRFLRHLAYLEVPDTTMPIPELHWFPAT
                     GTVR"
     gene            11749..13176
                     /locus_tag="HHX41_RS06980"
     CDS             11749..13176
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012886835.1"
                     /locus_tag="HHX41_RS06980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_182905241.1"
                     /transl_table=11
                     /translation="MLAVQLAALLGDSDAAGEGAGEALALLDGFDDALVHGLARLADER
                     AGAVTALAAAFAATPLGARLAEAADAVVSGSITQEHLTILAGGRIALSGAVHDALLTSL
                     DTALGRERAEWTSTSGGPASGDSGAQPAGNALEGVRSWLRELAITGWRGVDHDLVSAAD
                     QVIEALLGAPALRRLAVLLDGFAAELRASCPIGSAEHLPVRRWADLWTRAVLLSQDGVL
                     TGEPGPAATVSGRLLVLGVDVHEHGTAVQFQVHAVLEPADGGRSRLVRTSVTVAKVDTI
                     VGPALWKLPQRHKVLLAALADRRCIEIADVPLLDSGDLVWDDDRAFVSKPADPLATARL
                     CLPGALGPAVPPLDRAPVRIAEPVLVEGYKVTGDGSFDLGGAVIVVDTERLPDCGPLTP
                     KLVAASSACVGLLRWDGGRWTLQPLAVQVKVKRETVVVATGDWALGPTDPKAAKAEAKA
                     ADAVAVLRERAGRLLRR"
     gene            13173..14831
                     /locus_tag="HHX41_RS06985"
     CDS             13173..14831
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020545893.1"
                     /locus_tag="HHX41_RS06985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VWA domain-containing protein"
                     /protein_id="WP_310741807.1"
                     /transl_table=11
                     /translation="MSDDISTSAQAMGDDISTDAHPPTGGDATAHPGPAASAPPAVSAA
                     VSVAVSVAVSAAGSPAGDGGPTNADRNRRQLLYWRLLARLFDHEEQPALETASVAVVGD
                     LGLPAGLLDPAVSVDSLVQRFPELAAEFETLLTPDEHAPGGEVRRAALVSKLLLNAFAT
                     GAGDVSATQLATWQQDAAWLKRALCAGPAPGSGAGTAPGSGTGAQTGAGEPGGASGAQA
                     GTGPDAGPHTGPAAGFGQGPGGGTGREIGAGVGGDLAKVLADIEAGLVSRMRLREVLAD
                     PALARQLTPSMSLVEQLLRDKANLSGVALANAKALIRRYVDEVAEVLRTQVEKAGAGTI
                     DRSVPPKRVFRNLDIERTIWKNLTNWNPEDQRLYVDRLYYRHTARRTTPARLIVVVDQS
                     GSMVDSMVNCTILASIFAGLPKVDVHLIAYDTRAIDLTPWVHDPFEVLLRTNLGGGNDG
                     PVAMAMAQPKIADPRNTVMVWISDFYEFDRSQPLFDGIQAVHRSGVRFIPVGSVNSSGH
                     QSVNPWFRQKLKDLGTPVISGHIRKLVFELKNFLA"
     gene            14845..15960
                     /locus_tag="HHX41_RS06990"
     CDS             14845..15960
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012886833.1"
                     /locus_tag="HHX41_RS06990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AAA family ATPase"
                     /protein_id="WP_182905242.1"
                     /transl_table=11
                     /translation="MTNEMLRAPAEVKYAEELDWLESVDDGPKPFSWRLSPRMVRLFVL
                     GSERSDGLDREIPQKWFGDRSFVERSIVTLASDRGLLLIGDPGTGKSWLAELLSAAICR
                     DSTLVVQGTAGTTEDHIKYSWNVSMVIAKGQSRESMIPSPIMTAMEQGMIGRFEELTRA
                     TSDVQDALISILSEKYVSIPELDTDNTVFAKPGFSIIATANSRDRGVNDLSSALKRRFN
                     FVRIPVVTSKASEAEIVRFRTIELLRRHRIELDVPPALLDILLQSFADLRTAAASATSE
                     DEKLESALSTAEQIGVLEDAILHSHFFGDRTLRAETLAGALVGSLARRAPEDLAILNKY
                     WHGVVEPRSRNDGGEWTRFLDGGRQAISTLS"
     gene            15957..18764
                     /locus_tag="HHX41_RS06995"
     CDS             15957..18764
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019629301.1"
                     /locus_tag="HHX41_RS06995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5682 family protein"
                     /protein_id="WP_182905243.1"
                     /transl_table=11
                     /translation="MSTFDALRGQLLDAAEAFSGGGDVLAGILSGMVDDVDRMLREELE
                     IFPVCHHSPASALAMTRRLRDKRPKVVYLELCEDMRPLLDELRNCRLPVALQAFATQLD
                     GFPAGSGPLSVIAPVTEASAEYQAIAYALDTPGVEIVLVDRSVDHVFQWLPQETDGPDP
                     HEQAAQGDEAALHSDDVALHGDAVGVEIGDLRPRFAELEKHLLHHGKVRHWSEWWDQYV
                     EQPLTGADYDTYRQAMALIGSLFRRLRPDGHGRLAVDEERERYMWTRIREHLAESGADP
                     ADCLYVCGAFHAVSTVAEFGLRSEAPPYTIAPRTGTRWLHGLIPSSHSAIEAQFGLAQG
                     SVSIAAATWAKAVRRGGVTPYRLEGQQGGRAKQGGKRGGSAAPPVAAEPAADRLSGFLA
                     APPALDGLDEDELRGWCVDIVRLARRNGYLASTADAIAVFETSILLAGLRGRARPTPYD
                     FADAAVTCIEKDAVPGRRDVRRLCEILLGGDKIGMVGYDALPPLARDVYDRLEPLGLDL
                     TRRTQQRVLLDLRADPELEPCSDLLWTLRHLLPDGALRPIMGARRLGERPIQESWDVAL
                     GRHQREIVELGYEGVTVEQVLEQRLRRMAWDPQATAGAALAAVEDAILYVGGRRLPGEL
                     GACAVELLAAERTVDDAPEVLRRIRRLLTYYRASEPELPAWCEDFVTAGYSHYCTLLPT
                     AFADDETGVRQVGAMLGFLFTLESLALSLGCDRAQLELAVRQSHPRDPAKVALLWAAQT
                     QLGLLTREELRARCDELLANPLVVPAYPLYVSGFVQALEPVPGLAPFVVEALSKAFARL
                     PDPVLLPWLPTLICTLRQHAPELVPVLVREAGRTFPGALAELDAWTPPWERPAAPVRAA
                     RAAAAPSGPVSTLLARHPGACDAVAVLLGCTAEWGSTGHGNGEVAALLDRHPATTGAVA
                     ALLGA"
     gene            complement(18781..19650)
                     /locus_tag="HHX41_RS07000"
     CDS             complement(18781..19650)
                     /EC_number="3.5.3.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012703.5"
                     /locus_tag="HHX41_RS07000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="arginase family protein"
                     /protein_id="WP_182905244.1"
                     /transl_table=11
                     /translation="MLPTAVLQVPQWQGSSVEDARLLSLGAERLASLLTSSEPPTEPPT
                     GPSVRVVRVPVPDTAGTERDGVRALDVLNTVAARTRAALGECGTATVVTVGGDCGVQVE
                     PVSAALERHGDGLTVVWFDAHGDLNTPGSSPSHAFHGMVLRTLLGEGHPDLVPPRALHP
                     RQVILAGVRALDPAELAYAADAGLARHTVAELTADPGVLVPAVAAGGTAVYIHIDLDVL
                     DPEEFGSLSCPEAGGLSVAALRDAVRALTARFPLAGLGITEYAPRREEDQAVLASLVPA
                     LLADAATG"
     gene            complement(19785..20261)
                     /locus_tag="HHX41_RS07005"
     CDS             complement(19785..20261)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX41_RS07005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_169985697.1"
                     /transl_table=11
                     /translation="MTLDWCIEVALLSLLTFSSWPPSRAGLIRRQPRLLSDVVEAEFDQ
                     HTRLYVLTHVRAGGSTTTPLVANWDQITAYAAHCSNEIDTLYVCVLHGLQKWYWQCGLK
                     TDAPADTTGGRRTGSRRHAKPYECRQRIDAVLEALEDRRTPSACRFRRRPRTTG"
ORIGIN
        1 cctcggcgtg ggagtcgacg ccgtggtcct cgaccggtcg acggcgacac cggaactgct
       61 ccacgccgcc gggccggcca cggtgctgtc gctggggccc gctcccggcg tggccggggc
      121 ggccgacatc ctggcccata ccggcgacga cgcctatacc ggcgatgacc gcttccccgc
      181 cgtcacggcg cgcccggacg acgcggccct gctgaccttc accagcggca gcacgggcag
      241 gccgaagggc tgcgtgctca cctatcgggc tctggccgcg cactggtcca gccatcgcgg
      301 ctggtcgtcg atcgcgcccg gcttcgacga gtccttccac cgctacatgc tgttcggcac
      361 gctgtccagc ctggtggtgc tggatttcct ggcgccgtgc ctgctcggcg gcggcaccgc
      421 ggtgatcccc gatgaggacg gccggccgct gttcccgtac gcgatcgagc ggcaccggat
      481 caccggcgcg atcgtgaccg tgccccggct gtgtcagatg ctcgacctgc tccgtgagga
      541 gccggtcgac gtcggcagcc tgcgcgcgct gacggtctcc ggatcgtccg tcagcccgca
      601 tcggctgctc gaggcgctgg accggctggg ccccgtcgtc tacgtggggt acggcgcgac
      661 cgaggccggg gtcatctcca tgctccctcc cggggagggc cgcgacgcgc ccacctcggt
      721 cggacgcccg caccccagcg tcgagatcag cgtgcgcgac gaggagggcc gcccggtcgc
      781 cacgggacgc accggcgaga tccacgtgcg cggccccttc ctgatggcgg gctactggaa
      841 ccagccggag gaaacccgcg acgtgctgcg ggacggctgg ctgcgcaccc gcgatctcgg
      901 gcacctcgac gagaccggcc tgctgtacct ggccggccgg accagggacg tgatcatcgt
      961 gaacgcgatc gtcgtctacg ccgggcccat cgagggggcg ctggccggcc accccgacgt
     1021 ggccgaggcg tacgtgaccg gcgcgccgga cgagcggacc ggagaggccg tccacgcgtt
     1081 cgtggtcccc gctccgggcc gcactccgga ccacgctgcc ctggcagagc tggtacgcgc
     1141 cgagctcggc gcggacagcg tcccccggac gatcacgacg gtcgcctccg tgccggtcgc
     1201 gccgagcgga aaaccggaca agcgtgccct gctggagcgg catctgtcca cggcgctctg
     1261 atccatctct gagaatcgcc cgccaacact ggtgaaactt caaccatccc agtgagggag
     1321 gcgtcagtgc cggacaacat cctggactac ctggtggtcg gcgccggacc ggcgggcctg
     1381 cagatgggcc acttcctgca ccgggcgggg cgcgcctacc ggatcctcga ggcggcgccc
     1441 gagcccggcg cgttcttccg gaccttcccc cgccatcgca cgctcatctc catcaacaag
     1501 aagcacaccg gatgggacga cccggagctc aacctccgga tggactggaa ctcgctgctc
     1561 tcggacgacc cccgtctcct gttcacccgc tacagcgacc gttacttccc cgccgccgag
     1621 gacttcgtcc gctacatcga ggacttcgtc gccttgcagg gcctgcacgt cacgtacgac
     1681 gcgcgggtcg cggaggtcgc gcgcccggac gccgaaggcc ccttcctcgc gaccgacgag
     1741 tacggccgga cgtaccgggc gcggcgggtg atcgtcgcga cgggggtctc ccggcccaac
     1801 gtcccgccca tccccggcat cgagaccgcc gagcagtaca gcacccactc gaccgatccc
     1861 gcggactaca cggacatgcg ggtgctcgtc atcggcaagg ccaactcggc cttcgagacc
     1921 gccgacaacc tcatcgagac cgccgcggtc gtccacgtgg ccggaccgca cccggtgcgc
     1981 ctggcctggc ggacccactt cgtcgggcac ctgcgcgcgg tcaacaacaa cttcctcgac
     2041 acctaccagc tcaaactgca gaacgccgtg ctggacggcg acgtcaggcg catcgagcgc
     2101 cgggccgacg gctcctacct ggtgacggtg gccttcgtcc gggccgacga ggtcaccaag
     2161 gacatcccgt acgaccgggt gatcgtctgc accggcttcc ggttcgacgc ctccatcttc
     2221 tcgcccgagt gccgtcccga tctggcgatc ggggacaggt tccccgccct gaccccggcg
     2281 tacgagtcgg tcaacgtgcc agacctccac ttcgccggga cgatcaccca gtcgctcgac
     2341 ttcaagcgcg gcaccaacgg gttcatccac ggtttccggt acggcgtacg cgccctgcac
     2401 cgcatgctgg agaacaggca tcacggcgtc ccctggccgg gccgcgacct ccccgcggat
     2461 ccggacgcgc tcgcggcggc cgtgctcgaa cgggtcaacc gcagctcggc gctgtggcag
     2521 cagttcgggg tgctggccga cgtgatcgtc ccggacgggc tcggcggcat gcgctacctg
     2581 gaggagctgc cgatcgacct gcagggtccg ccgatcggcg acgcgggcca cttcgcgatc
     2641 accctggagt acggcccgca ccacgaccag gtcgacccct tcgatctctc ggtggggcgg
     2701 atcaggcaga gcgacgcgga gcgtgcgcac gagggccact acctccaccc cgtcgtacgc
     2761 cgctatcggg gcggtgtcgt ggaggccgtc caccacgtca ccgagaacct ggagaacgac
     2821 tggacctcgg atgaggtgca cctgcgcccg ctccgggatt tcttcacgcg tcagagcctc
     2881 ccggtctcgg tgtgacggcc gtgctgacga ccatccggga gttcgaggcg gcggcccgcg
     2941 accggctgga ccccgcccac tacgactaca tcgccggcgg ggccggcgac gaggtcaccg
     3001 tgaaggccaa cgaggcggcg ttcgcccggc tcgcgctgct gccgcgggtc cttcgcggcg
     3061 cggggagtcc gcggatcggg gtcaccctgc tgggcagccg cgcggagatg ccggtgctgg
     3121 tggcgccgac cgcgttccac cggctcgccg accccgaggg ggagaaggcc acggcccgcg
     3181 cggcggccgc cgcggggacc atcatgatcg tgagcatggc cgccaccgtc gccgtcgagg
     3241 acgtcgcggc cgcggcgccg ggcgccaccc tgtggttcca gctctacgtc cagcccgaca
     3301 tggcctttac cgaggcgatc gtccggcgcg ccgaggcggc cgggtgcgcg gcgctggtcg
     3361 tcaccgtgga ctcccccgcc cgtggccgca gggatcggga tgtgcgccgc ggcttcgacg
     3421 atctgcccga gggcatgcgc tgcgagaacc tgcgcgacgg cgacgccgag tcggtgcggc
     3481 cgatcgtcat gtcgcccgcg atctcctggg agcacgtcga ctcgctgagg cggatgacgc
     3541 ggctgccgat cgtgctcaag ggcgtcacgc accccgccga cgcgcgcctc gccctggacc
     3601 acggcgtggc ggcgctgtac gtctccaacc acggcgggcg gcagctcgac accgtcccgg
     3661 ccaccgtcga cctgctgccg gagatcgtgg ccgtcgtcgg cggggccgta ccggtgctgg
     3721 tggacggagg gatccggcgc ggcaccgacg tggtcaaggc gctggcgctc ggcgcgtccg
     3781 ccgtcgcggt cggccgtccg gtggtctggg gcctggcggc ggacggcgag tgcggcgtgg
     3841 cccgcgtgct cgggctgctg cgggacgagg tcgagcacgc gctcactctg tgcggcctgg
     3901 cctcgccgca cgacctggag ccggggctgg tgcggcgatg ctgacggcgg tgtgggtggc
     3961 gctgtgggtg gctggggcca tcgtcgtgat cagcctgccc cggtggctcc ccgggcgcgt
     4021 cgtcgcgctg cgcgggtggg tgttcacgag gatcaacggc gaggagagca tcgcggtccc
     4081 cggcgacctc gtcggcgtcg accggttcag ggagatctac tcccacccgg cggcctccgg
     4141 ccgcagcgaa ggagccgtcc tgtccgacct gttctggtac tggctgtcgc ccgggcccga
     4201 gatgcaccag gagcacctgg aggcggggga gcggtacgac gccgtcgccc tggccacccg
     4261 ccgcatcctg tccctgccgc gggcgcaggt ggaggagctc acccgccggt gcgtccgccg
     4321 ggcactggag ggcgggcgcg ggctggtccg gctgcgcgat ctgatgatgc cggcctgggc
     4381 cgagttctcc tacgagctcg tcttcggcga gccgtgcccg ccgcaggtcc gtgacctcat
     4441 cgtcggcaac gcggacgacg tcgtgaccgc gctcaagtgc tgtggcctgc ggcacatgga
     4501 ccggcgcgac cggctgaccg cctatctcgt cgagtcgctg cccagggtga ggcacgagct
     4561 cccggcgggc ctgacacccc gggagcaggc gctgtatctc catggggcct tcttcaccac
     4621 cgctgtcgtg cagatgtcgg aggccatggc tcacgtgctg atggccctgg cccagcatcc
     4681 ggacgtacag gacagggcgc ggagcggcga cgaccactac ctcgaccagg tgatcgcgga
     4741 gacgctgcgg ctctacccgc tcttcggcat cgcccaccgc gtcaccaaag gcgacatccc
     4801 cctgggcgag ggggtcgcca tcccggccgg ctcggtgctg tgcttcgact accccgcgtt
     4861 ccaccgctcg ggcttccccg atccggagcg cttcgatccc ggccgcttcg cccccgggca
     4921 caccccggtc agggagctca accacatccc gttcggcatg ccggcgaacc gtccctgccc
     4981 ggcgtggcgg ctcgcgccgc tcgccatgcg ggtcgcgacg cgggaggtcc tgcgggcgta
     5041 cgcgctcgac accaccgcgg ggcacacccg gtcgctgccc aaccggggac cgtgcctcct
     5101 caccccgccg gccgcagggc gcgggccggg acggcgcctg acgctgctgt ccatgcgcct
     5161 gcgggacggc tgggaggacg tctggcgcag cctcgtgcag ctcgtcctcg gcacgtacat
     5221 ggtgtgggac gcgcgtcggc tgcgtctgtg cgagcgccac ttcacccgcg acgcccgtcc
     5281 cgagggcacg tagacgaccg gccgatccca ggcccgacca cgagcggagg cacatgccat
     5341 gcccgttccg gccctccttt cagtggaggc gcacactgcc gaccccaacc tggagctggc
     5401 cctcagggtg ttgccggccc tggccgtcat cctgctggcc gcggcgctgt gcggccggct
     5461 ggccaccctg gtgatgcagc cgcgcgtcgt cggcgagatg gtcgccggcg tcctgctcgg
     5521 gccgacgctc ctcggcgcgc tgttccccgg cgcccaggcg gccctgttcc ccgccgaggt
     5581 cagaccggtc ctgtacgtgc tcagcaccct cggcctgacg ttgtacatgt tcctggtcgg
     5641 ggccggaatg gaccacgacg cccgggcgcc gggcgagctg cgcaaggcga gcgtgctggc
     5701 ggcgtcgggg atcggctcac cgctggtcct cggcggcgcc gccggtctcg tcctgtggga
     5761 ccgcctctcc cggccggacg tcggccggat cgagttcgcc ctgttcctcg ggggagcgct
     5821 gtcgctgacc gcgttcccca tgctcgccag gatcctgtac gaacgcgggc tgcagaacac
     5881 ccgcatcggc cggatcgccc tgctcgccgc ctccatcgac gacgccgtgg cctggtgcct
     5941 gctcgccgcg ttgtcggcgg cgcacctggg cggcggtccc ggcgacacgc tgcgcaccat
     6001 cgccctggca ggggtgttcg cggcggtgat gctcggggtg gtggctccgc tgctgcgccc
     6061 tctgggccgc cgcgtcgcgc gtaccgggcg cctcggcgcc ggcgccgtgt acgtgatcgt
     6121 gctggtgccg ctcgcggccg ggtggatcac cgacgcgatc ggcgtctact cggtgttcgg
     6181 cggcttcgtc gccgggttgt ccatgccgcg cgagccggcg ttccgcgccg cgctgcacga
     6241 ccggatgatg gatgtcgtat cgaccctgct gctgcccgtc ttcttcgcgt tctcggggct
     6301 gaacacccat ctcggcggca tcgccggggg ctccgcgctc ctggcgttcg cgctgattct
     6361 gaccctggcc ttctgcggga agtacttcgg ctgctcgctg gcgacacggg cgctgggatt
     6421 cggctggcgc gaatcctggg ccatgggcgc gatgatgaac gcccgcggac tgatgatcct
     6481 catcttcatc aacatcggcc tggcgcaggg gatgatcacg caggagctct tcgcgatgct
     6541 cgtcctcgtg gccgtgctca ccaccgcggg ggccctgccg ctgtacaaac tggcgctgcc
     6601 ggagcgccac gagcgagccg atgcgggcag cgtgggtagt gcggcccgga tgggggcggc
     6661 ggcgggagaa accggtttca tttaatttca ccggagagtc ggacattcgt ggaatagagg
     6721 gcgatttccc tggagtggaa ttccgaagtc tggatatctc ctgatatcgg tgacacggtt
     6781 ggtcggtggc acggataccg gggacatccg aaccgcgctc ccggcgcctg ctgctcgtgg
     6841 aggacgaccg cgagctggga gacatgctgg tcgaggtgtt caccgaccag ggctacacgg
     6901 tcgacctggc gctggagggc cagcggggcc tgcacctggc gctgacccgc ggctacgacg
     6961 cgatggtcat cgatcgcggg ctgcccgtgg tcgacgggct cgatctgctg cggcggctgc
     7021 gccgccaggc ggtcaccgtg ccggtgctga tgctcaccgc cttcggcgct ctcgccgacc
     7081 gggtgaccgg actcgacgcg ggcgcggagg actacctggt caagccgttc gagatcgacg
     7141 agctgctggc cagggtgcgc gccctgcacc gcaggaacct ggaccaggcg acgctgctgc
     7201 cgctcggcgc cggctggctc gactccgcgt cctgcgtcgt acggctgccg tccggcgagc
     7261 aggtgacact gtccggccag gagtgccggc tgctccacgc gctggcggcc cgcccccggc
     7321 aggtgcacac gcgcacctcg ctgcggcagc gggtcttcga cggcgccagg accgagtcga
     7381 tcgtggacac ctacgtctac tacctgcgca ccaagctggg gcccggcgtc gtccgtaccg
     7441 tgcggggcgt ggggtaccgc ctgggtgagc tgtgaagacg acacggtcct ccgacccgga
     7501 gcggcgcctg ctcatcctga cccgccgccg gatcaccgcg caggtggcgg ccgtgttcac
     7561 gctggcgatc accctcctgg gcacgctggt ctactgcgtg gtggccgacg cgcaggacgc
     7621 caccgcccgg cgcgatctgg ccgtggccgc gatgtcggcc ccgatggacc acccgccgcc
     7681 ctgcgtatgg ctgttcgaac tccgggcgga caccgtgcgg agatccccgg gggcgccgga
     7741 gggcctgccg gtgcgcgaga cactcgaccg ggtcgccgcc gacggccgca cccgggtcga
     7801 cgtcgcggaa gtcggcggcc acacgtacct ggtccgtacg cagcggcgcg gcgacgtgcc
     7861 cctgcaggcg gtgatggacc tgtattaccc cgtcaccgag cggcagcggc tgctgcgcac
     7921 gctctgcgcg gccgaggtcg cggccctgct ggtggcgttg ctgatcggtc aggtcctcgc
     7981 ccgccgggcg atcgcgccgc tgggcgaggc cctcgaccgg cagcgccggt tcaccgccga
     8041 cgtcagccac gaactgcgca gcccgctgac ccggctgcac gtccgtgcgc agctcgccgc
     8101 ccggcgcctg agacgggagc ccgatcctct tctcgtcgtg ggcgacgtcg accggctggt
     8161 caccggcatc gggcagctgg gcgaggtgat cgaggacctg ttgctgtcga cccagctcag
     8221 gcagagccgc cggccgttcg ggcccgcgga cctggccgcc ctggcggagg aggcggccga
     8281 cgccgaggcg gcccgcgccg ggcagcgcgg ggtgaccatc gacctgcggc gggatcccgg
     8341 cgatcacgtc gtgtgcggag cgccgtccgc gctgcgccgg gtgatctccg cgctcctcga
     8401 caacgcactg cgccacacct ccacgggcgg ccacatctgg gtgagcgtgt gttcggggcc
     8461 gcagaccgtt cagctcagtg tgcgggacga cggcgtgggg ctggacccgc gtgacggcga
     8521 gcgcctgttg gtcaggcatg tcggcgcgcc ccacaccgga ggtctcggca tcggcctggc
     8581 tctcgtgagc gaggtgatga acgcgcacgg cggcgcgatc gacgtggacg ggcggccggg
     8641 agccggagcc accttcacca tccgtctccc tcgggcggcg ccggaccccg ctccgcacct
     8701 gtcccggatc ggtcttcctg ccccggcggc cgcggagcga gacgaacaga acgccggagg
     8761 cgaccgcctc cggccccggc gacgcctgcc tgtagtcctc cgcggatggc ggagcgtgct
     8821 cacgagggcc aatgcgcggt gaggggatga tcgggcgcgg ccgcggcgtc gagcagcgca
     8881 cgggcggcgg accgggcccg ctccgcgggg tcggcggccg tgcccatggc ggcggcgacg
     8941 atggccccct ccaccagcag cagaagctgg tcggcgagca ggtccggatc ggcggccccc
     9001 gcctcggccg tgagcgtgcg aagccttccc cgcagcgcgt tcttgtgcgc ccgcgccgcc
     9061 gccacgacgg gcggtgacgc cgggccgagc tcgccgaagg cgttgacgaa cgcacagccg
     9121 cggaagtcgg ccgtgccgaa ccactcggcg aggaagccga agacggcgag cacgcgctcg
     9181 cggggctccc cgacactgcc gagatggtcg gacagagcgt cgttccaccg tcggtcgcga
     9241 tgttccaggt acgcctccac cagcgcgtcc ttggacgcgt agcactggta gagccgcttg
     9301 agcgagaccc ccgcggcgtc gcggacctgg tccatgccca cggcctggat gccccgcgcg
     9361 tagaacaacc gctcggcggc gtccaggatg cgccggcgcg cctcttctcc gtccatccgc
     9421 acccgtcggg tcccgtccac ccgccccctc ctcaccgagg aaaacgctcg ttctctacga
     9481 tacgtaggga gaacgatcgt tctcccgtgt tggaaggaca gccacgatga gcacacgccc
     9541 gccgcttccg ccgttcaccg aggagaccgc caggcagaag gtccaggccg ccgaggacgc
     9601 ctggaacacc agagacccgg aacgcgtcgc gctcgcgtac accgaggact cggtgtggcg
     9661 caaccgatcg gagttcctga ccggacggga ggagatcgtc gccttcctgc gccgcaagtg
     9721 ggagcgcgag caggactacg ccctgcgcaa ggacctgtgg acgttcggcg gcgaccgcat
     9781 cgccgtacgg ttccagtacg agtggcagga cgccgacggc cggtggtggc gcagctacgg
     9841 caacgagctg tgggagttca ccgccgaggg cctgatgagc cgcagggagg cgagcatcaa
     9901 cgacatgccg atcgaggaga gcgagcggcg catccgcggg ccgcgccccg agtccgaacg
     9961 cggcgccggc cttccgctcg cctgaccgtg gcccgggcgt ttacctggcc atgctgccga
    10021 gggatccggc gcggagcgcg tccggcgagc aggcggggca gtccggcgcc ccgggatgac
    10081 gcgtgtagac gtgctggtcc ggggccgcga ggttgatccc ggtgacgtag ctgcccgagg
    10141 tcgccgggat cccggtcagg aacgcgacga ccgcctgggc ggtcagatgg cccgacaccc
    10201 cggcggaggg cgcgatggcg cccggcccgc cgaggtcgac ggggattccg ggcgcgagag
    10261 gggcgtcgac gctcgcggtc aggcactcgt agcacgggcc gccgggggtg aaggccgcca
    10321 cgctcaccag cgggccgttg tagccgccga gcgcccacgg gatcttctcc gacagacagg
    10381 cccggttggc ccagacgcgg atgccgcccc tgcccgcggg ctcgtcggcg cacatcgcca
    10441 ccgcgtcgaa cccgcgtacg aggtcgagca tgtcctcctc gcactcgacc ggccgggcct
    10501 ccgcggtgac gcggacggag gagttgacct cggcgagccg ggcggcggcc acgtccacct
    10561 tgggactgcc gatgtcggac tcccggtaga gggcctggcg ggtcaggtcg ggcagctcga
    10621 ccgggtcgcg gtcgacgcag tggatctcgc cgacgccgca cgcggcgagc gcccaggccg
    10681 tgtggctgcc ggtcccgccc aggccgagga cgagcacacg ggagcgcttg aggcggacct
    10741 gcgcctccca gccgcgctcg gggcgggtgg gatcgacgtc gcggaagaac gccgcgttgc
    10801 gcgagtagcg ttcgagttcc cgcaggctga gctcctcggg ccgcgggccg gcggcgtcct
    10861 ccacacaccc cgagctcagc aggaggtcga cgacgtcggc cgcctcggcc tcggtcagcc
    10921 ccgggaacgc gcgatgcagg cgggcgacga cctcctccgg ggtcctcgtg ccgtccatcg
    10981 cgttcagggc cgcccaggcg tggccgtccg gatcgctgat ctccgctgtc acgccgttga
    11041 ccgacccgcc tatccggatc cggtcgttgc cgtacctgtg ggggcggtgc tgggctttca
    11101 cgcggggcaa ccgcaagggg acctctcggc atcgcgagcg ggacaagaat cgacaggtgg
    11161 atctttctgt aagtgtccgt ctatgtcaag actctggatg ggcggccgag ccgttttgtc
    11221 gtacggctcg gatacgttcc ggatcatgac agagcgttcc cccgacggcg cgaccgtgtg
    11281 ggcgcgaaac agcaggctgc gggtggtgcc gccggtccag ccgcgcaagc tggcgaaggt
    11341 ccccttcgtc gagctggcgg acggcaggct gcagggcgtg gtgtcgagcg gttcggacat
    11401 cggccgggtc tacgtctcct ccatcgccgc cggcacccac aactacaact gcagcaccaa
    11461 caacaaccgc ccctgcggcg gcctgtacgg cgcgccgtgc aagcacctgc gcgccctggt
    11521 cgccgaggcc gtcctgcagt acggcgccga ccgcgtgtcc cgttatctgc gggcggaggt
    11581 ccccgagggc gcggagctgg ccgactgcct gcgcggcatc catgagcccg cccccgccgc
    11641 ggtcgtgttc agccggttcc tgcgtcacct ggcctacctg gaggtgcccg acaccaccat
    11701 gccgatcccg gagctgcact ggttcccggc cacggggacg gtgcgctgat gctcgccgta
    11761 cagctcgccg ccctgctcgg cgactccgat gccgccggcg agggagccgg agaggcgctc
    11821 gcactgctgg acggcttcga cgacgccctg gtgcacggcc tcgcccggct cgccgacgag
    11881 cgcgctggcg cggtgaccgc gctggccgcg gcgttcgcgg ccactcccct cggtgctcgg
    11941 ctggcggagg ccgccgacgc ggtcgtgtcc ggctcgatca cccaggagca cctgacgatc
    12001 ctggccggcg gccggatcgc gttgtccggc gccgtccacg acgccctgct cacgagcctg
    12061 gacacggctc tgggccggga gcgcgcggaa tggacgtcca catccggggg ccccgcgtcc
    12121 ggcgactccg gcgctcagcc cgccggcaac gcgctcgagg gcgtccgctc ctggctgcgc
    12181 gagctggcga tcaccggctg gcgcggcgtc gaccacgacc tcgtctccgc ggcggaccag
    12241 gtcatcgagg cactgctcgg cgcaccggcg ctgcgcaggc tcgcggtgct gctggacggt
    12301 ttcgccgcgg aactgcgcgc gtcctgcccg atcggctccg cggagcacct gcccgtgcgg
    12361 cgctgggccg acctgtggac ccgggccgtg ctgctgtcgc aggacggcgt actgaccggc
    12421 gagcccggcc ccgccgccac ggtgtcggga cggctgctgg tgctcggcgt cgacgtgcac
    12481 gaacacggca ccgccgtcca gttccaggtg cacgccgtcc tggaacccgc cgacggaggc
    12541 cggtcccggc tggtgcgcac ctccgtcacg gtggccaagg tcgacaccat cgtcgggccc
    12601 gcgctgtgga agctgccgca gcgccacaag gtgctgctgg ccgcgctggc ggaccgccgc
    12661 tgcatcgaga tcgcggacgt gcccctgctc gacagcggcg acctcgtctg ggacgacgac
    12721 cgcgccttcg tgagcaagcc cgccgacccg ctggccaccg cccggctgtg cctgcccggc
    12781 gcgctcggcc cggcggtgcc gccgctcgac cgggcaccgg tacgcatcgc cgagcccgtg
    12841 ctggtggagg gctacaaggt caccggggac ggctccttcg acctcggcgg cgccgtcatc
    12901 gtcgtggaca ccgaacggct gcccgactgc ggcccgctca cgcccaagct ggtggcggcc
    12961 tcgtcggcgt gcgtggggct gctccggtgg gacggcggcc gctggacgct gcaaccgctg
    13021 gccgtgcagg tgaaggtcaa gcgcgagacc gtggtggtcg ccaccggtga ctgggcgctc
    13081 ggccccaccg accccaaggc ggccaaggcc gaggccaaag ccgcggacgc ggtggccgtg
    13141 ctgcgggagc gagccgggcg gttgctgcga cgatgagcga cgacatctcc acgagcgccc
    13201 aggcgatggg cgacgacatc tccacggacg cccacccgcc gacgggcggg gacgccaccg
    13261 cgcaccccgg tcctgcggcg tccgcgccgc ctgccgtttc cgcggccgtt tccgtggccg
    13321 tttccgtggc cgtttccgcg gccggttccc ctgccgggga cggcggaccg acgaacgccg
    13381 acaggaaccg gcgtcagctg ctctactggc ggctgctggc ccggctgttc gatcacgagg
    13441 agcagccggc gctggagacc gcgagcgtcg cggtcgtcgg cgacctgggc ctgcccgccg
    13501 ggctgctcga ccctgccgtg tcggtcgact cgctggtgca gcgtttcccc gaactggccg
    13561 ccgagttcga gaccctgctc acgccggacg agcacgcgcc gggcggcgag gtgcgccggg
    13621 cggcgctcgt ctcgaagctg ctgctcaacg ccttcgccac cggcgcgggt gacgtcagcg
    13681 ccacccagct cgcgacctgg cagcaggacg ccgcctggct caagcgggcc ctgtgcgcgg
    13741 ggccggcacc cggatcggga gcgggcacgg cacccggatc gggaacgggc gcgcaaacgg
    13801 gtgccggaga gccgggcggc gcgtccgggg cgcaggccgg gaccggaccg gatgccggac
    13861 cgcacaccgg gccggcggcc gggttcgggc aggggcccgg cggcgggacc ggccgtgaga
    13921 tcggcgccgg ggtcggcggc gacctggcca aggtgctggc cgacatcgag gccgggctgg
    13981 tcagccgcat gcggctgcgc gaggttctgg cggatccggc cctggcgcgg cagctcacgc
    14041 ccagcatgtc gctggtcgag cagttgctgc gcgacaaggc caacctgtcg ggcgtggcgc
    14101 tggccaacgc caaggcgctg atccgcaggt atgtcgacga ggtcgccgag gtgctgcgca
    14161 cgcaggtcga gaaggccggc gcggggacga tcgaccggtc ggtgccgccc aaacgggtgt
    14221 tccgcaacct ggacatcgaa cggacgatct ggaagaacct caccaactgg aacccggagg
    14281 accagcggct ctacgtcgac cggctctact accggcacac cgcccgccgg accaccccgg
    14341 cccggctgat cgtcgtggtg gaccagtcgg ggtcgatggt cgactccatg gtcaactgca
    14401 cgatccttgc gtcgatcttc gccgggctgc ccaaggtgga cgtccacctg atcgcgtacg
    14461 acacgcgggc gatcgacctc acgccgtggg tgcacgaccc gttcgaggtg ctgctgcgca
    14521 cgaatctggg cggcggcaac gacggccccg tcgcgatggc catggcccag ccgaagatcg
    14581 ccgacccgcg caacacggtg atggtgtgga tctcggactt ctacgagttc gaccggtccc
    14641 agccgttgtt cgacggcatc caggcggtgc accgctccgg ggtcaggttc atcccggtcg
    14701 gctcggtgaa cagctcgggt caccagagcg tgaacccctg gttccggcag aagctcaagg
    14761 acctgggcac gccggtgatc tcgggccaca tccgcaagct cgtgttcgaa ctcaagaact
    14821 tcctcgccta ggagacccct tcacatgacc aacgagatgc tccgcgcgcc cgccgaggtg
    14881 aagtacgccg aggagctcga ctggctggag tccgtcgacg acggccccaa gccgttctcc
    14941 tggcggctca gcccccggat ggtccggctg ttcgtgctgg gcagcgaacg gtccgacggc
    15001 ctcgaccgcg agattccgca gaagtggttc ggcgaccgga gcttcgtcga gcgcagcatc
    15061 gtgacgctcg cctccgaccg cggcctgctg ctgatcggcg accccggcac cggcaagagc
    15121 tggctggccg aactgctgtc cgccgccatc tgccgcgact ccaccctggt cgtgcaggga
    15181 acggcgggca ccaccgagga ccacatcaag tattcgtgga acgtctcgat ggtgatcgcc
    15241 aagggccagt cccgcgagtc gatgatcccc tcgccgatca tgacggcgat ggaacagggc
    15301 atgatcggcc gattcgagga gctgacccgc gccaccagcg acgtgcagga cgccctgatc
    15361 tcgatcctgt cggagaagta cgtctccatt cccgagctcg acaccgacaa caccgtgttc
    15421 gccaagcccg gattctcgat catcgccacc gccaacagcc gcgaccgggg cgtcaacgac
    15481 ctgtcctcgg cgctgaaacg gcggttcaac ttcgtccgca tccccgtggt gacgagcaag
    15541 gccagcgagg cggagatcgt ccgtttccgc accatcgaac tgctgcgccg gcaccgcatc
    15601 gagctggacg tgccaccggc gctgctggac atcctgctgc agagcttcgc cgacctgcgc
    15661 accgcggcgg cctcggccac gagcgaggac gagaagctgg agtcggccct gtccaccgcc
    15721 gagcagatcg gcgtgctgga ggacgccatc ctgcacagcc acttcttcgg cgaccgcacg
    15781 ctgcgcgccg agacgctggc cggcgccctg gtgggctccc tggccaggcg cgcccccgaa
    15841 gacctggcca tcctcaacaa gtactggcac ggggtggtcg aaccacgcag caggaacgac
    15901 ggaggcgagt ggacgcggtt cctcgacggc ggccgtcagg cgatctcgac gctgtcatga
    15961 gcaccttcga cgccctgcgc gggcagcttc tcgacgccgc cgaggccttt tccggcggcg
    16021 gggacgtcct ggccggcatc ctgtccggca tggtcgacga cgtcgaccgc atgctgcgcg
    16081 aggagctgga gatcttcccg gtctgccacc actcgccggc ctccgccctg gccatgaccc
    16141 ggcgactgcg cgacaagcgg cccaaggtcg tctacctgga gctgtgcgag gacatgcgcc
    16201 cgctcctcga cgagctgcgc aactgcaggc tgccggtggc gctgcaggcg ttcgccaccc
    16261 agctggacgg gttcccggcc ggctccggac cgctcagcgt gatcgcgccg gtcacggagg
    16321 cgtcggcgga gtaccaggcg atcgcgtatg cgctcgacac ccccggcgtc gagatcgtgc
    16381 tggtcgaccg ctcggtggac cacgtcttcc agtggctgcc gcaggagacg gatggtccgg
    16441 atccgcacga gcaggccgcg cagggcgacg aggcggcact gcacagtgac gatgtggcgc
    16501 tgcacggtga cgccgtcggc gtcgagatcg gcgacctgcg gccgcgcttc gccgagctgg
    16561 agaagcacct gctgcaccac ggcaaggtgc ggcactggtc ggagtggtgg gaccagtacg
    16621 tcgaacagcc gctgaccgga gcggactacg acacctaccg ccaggcgatg gcgctgatcg
    16681 gcagcctgtt ccggcggctc cgccccgacg ggcacggccg cctggccgtc gacgaggaac
    16741 gcgagcgcta catgtggacg cgcatccgcg agcacctcgc cgagtcgggc gcggaccccg
    16801 ccgactgcct gtacgtgtgc ggagccttcc atgccgtcag cacggtcgcg gagttcggcc
    16861 tgcggtccga ggcgccgccg tacaccatcg ccccgcgtac gggcacccga tggctgcacg
    16921 ggctgatccc ctccagccac tcggcgatcg aggcgcagtt cggcctggcc cagggctcgg
    16981 tgtccatcgc cgccgccacg tgggccaagg cggtcaggcg cgggggcgtc accccgtacc
    17041 ggctggaggg gcagcagggc ggccgggcca agcagggcgg caagcggggc ggcagtgccg
    17101 caccgcccgt cgcggccgag ccggcggccg accggctgtc ggggttcctc gccgccccgc
    17161 ccgcgctcga cggcctggac gaggacgaac tgcgcggatg gtgcgtcgac atcgtgcggc
    17221 tggcccgccg caacggctat ctggccagta cggccgacgc catcgccgtg ttcgagacgt
    17281 cgatcctgct cgcggggttg cgcggccggg ccaggcccac gccgtacgac ttcgccgacg
    17341 cggccgtgac ctgcatcgag aaggacgccg tgccaggccg ccgggacgtc cggcgcctgt
    17401 gcgagatcct cctgggcggc gacaagatcg ggatggtcgg ctacgacgcg ctgcccccgc
    17461 tggcccgcga cgtgtacgac cggctggagc ccctcgggct ggacctgacc aggcgcacgc
    17521 agcagcgggt gctgctcgac ctcagggcgg acccggagct ggagccgtgc tcggacctgc
    17581 tgtggacgct gcgccacctg ctgcccgacg gtgcgctccg gccgatcatg ggggcacgcc
    17641 gcctcggcga gcggccgatc caggagagct gggacgtggc gctcggccgg caccagcggg
    17701 agatcgtcga gctgggctac gagggcgtca cggtcgagca ggtgctggag cagcggctgc
    17761 gccgcatggc gtgggatccc caggccaccg ccggggcggc gctcgcggcc gtcgaggacg
    17821 ccatcctcta tgtgggcggc cggcgcctgc ccggcgaact cggcgcctgc gcggtcgaac
    17881 tgctggccgc cgagcgcacc gtggacgacg ctcccgaggt gctgcgccgc atcaggcggc
    17941 tgctgaccta ctaccgggcg agcgaaccgg agctgcccgc ctggtgcgag gacttcgtca
    18001 cagccgggta ctcgcactac tgcacgctgc tgcccaccgc tttcgcggac gatgagaccg
    18061 gcgtacgcca ggtcggggcg atgctcggct tcctgttcac actggagagc ctcgcgctgt
    18121 cgctgggctg cgaccgggct cagctcgaac tggccgtacg gcagtcgcat ccacgggacc
    18181 cggccaaggt tgcgttgctg tgggccgccc agacgcagct gggcctgctg accagggaag
    18241 agctgcgcgc ccgctgtgac gagctgctgg ccaacccact cgtcgtgccg gcgtatccgc
    18301 tctatgtgag cggattcgtc caggcgctcg aacccgtgcc cggcctcgcg ccgttcgtgg
    18361 tcgaggcgct gtcgaaggcc ttcgcgcgac tgcccgaccc ggttctgctg ccgtggctgc
    18421 cgacgttgat ctgcaccttg cggcagcacg cgcccgagct ggtccccgtc ctcgtccgcg
    18481 aggccgggcg gaccttcccc ggcgcgctgg ccgagctgga cgcctggacc ccgccctggg
    18541 aacggccggc cgcgccggtc cgagcggccc gggcggcagc cgcgccgagc gggccggtgt
    18601 ccacgctgct ggcccggcac ccgggggcgt gcgacgccgt cgccgtgctg ctcggctgta
    18661 cggcggagtg ggggagcacc gggcacggaa acggcgaggt ggcggccctg ctcgaccggc
    18721 atccggcgac gaccggcgcg gtcgccgcgc tgctcggcgc gtgagcctgc acccgcgcct
    18781 tcacccggtg gcggcgtcgg cgagcagggc ggggacaagc gaggcgagga cggcctggtc
    18841 ctcctcccgg cggggggcgt actcggtgat ccccaggccg gccaggggaa agcgggccgt
    18901 cagcgcgcgt acggcgtccc gcagtgccgc gacggacaga ccgccggcct cgggacagct
    18961 gagcgacccg aactcctccg ggtcgagaac gtcgaggtcg atgtggatgt agacggcggt
    19021 gcccccggcg gcgacggccg ggaccaggac gccgggatcg gccgtcagtt cggccacggt
    19081 gtgccgggcg aggcccgcgt cggcggcgta ggccagctcc gccgggtcca gcgcgcgaac
    19141 tccggcgagg atcacctgcc gggggtgcag ggcccgcggt ggaaccagat cggggtgccc
    19201 ttcgcccagc agggtgcgca ggaccatgcc gtggaaggca tgcgagggtg aggatccggg
    19261 cgtgttgaga tcgccgtggg cgtcgaacca gacgacggtc agcccgtcgc cgtgtcgctc
    19321 cagggcggcc gacaccggct ccacctgcac gccgcagtcg ccgccgaccg tgacgaccgt
    19381 ggccgtgccg cactcgccga gcgcggcgcg ggtgcgggcg gcgacggtgt tgaggacgtc
    19441 cagggcccgg actccgtccc gctcggtgcc cgcggtgtcc gggacgggca cccgcacgac
    19501 cctgacggac ggcccggtgg gcggttcggt gggcggctcg ctggatgtca gcagagaggc
    19561 cagccgttcg gcgccgaggg acaggagccg tgcgtcctcg acgctcgacc cctgccattg
    19621 gggcacctga agcaccgcgg tcggaagcac cgtctgatca ttccatgccc acgcctgccc
    19681 gggcggggcc cgtacgcgtc gcgctcggac gggggtgccg tgcgcgtcgt ggtgggcccg
    19741 tcatgccggg tccgttgtgg tcgggtcctc gccggtggtg ttcctcaccc agtggttctg
    19801 gggcgccggc ggaaccggca ggccgacggc gtacgccggt cctccagtgc ctccagcacg
    19861 gcgtcgatcc gttgccggca ctcgtacggc ttggcgtgcc gccggctccc ggtccgtctg
    19921 cctccggtcg tgtcggccgg ggcgtcggtc ttcaggccgc actgccagta ccacttctgc
    19981 aggccgtgca gcacgcatac gtaaagagtg tcgatctcgt tggaacagtg tgccgcgtac
    20041 gccgtgatct ggtcccaatt ggcgacgagg ggcgtggtgg tggagcctcc ggcgcggacg
    20101 tgcgtcagca cgtacaggcg cgtgtgctgg tcgaactcgg cttcgacgac gtcgctgagc
    20161 aggcgcggct gccgccggat caggccggcg cgggacgggg gccaggacga gaacgtgagc
    20221 aggctcagca gcgccacctc gatgcaccag tccagagtca tcggggcttc ccttcgtcgg
    20281 aggccgtacc gggattcgtc cccgaggcgg gggctcggtc gcgccgtcgc cggggtgacg
    20341 tgaccgggac gcgggtacgg tccacgggtg agacggaaca aaggagagcg gctgcgacga
    20401 tgccggtcgc agccgctctc tcgcggcgcg tttccatccg cgcccctgcc ccaggtagcg
    20461 gggcgtggat gtcaacgatc atccggtgtc ccggaaggca gctccgccgc gaaccggacg
    20521 agggacgtcc actagctacc cccacgcccc tcgcctttct cggggatggc gcgcatccgc
    20581 cgagagcatt tcggtgctgt cgtcgccggc gctgtgggat gtccgttcac cgcgccggct
    20641 gacaccaggg cgagcggtta gcggtgcccc cagccgccct gacccggacc gccggagccg
    20701 ccgggaccgc cgtggccgcc ccagctaccg ccccccgggc cgccctgacc cgggccgccc
    20761 tgacccgggc cgccgtggcc gccctggccg gggccgccgg gaccgccctg acccggaccg
    20821 ccgggaccgc cctgacccgg accgccaggg ccgccgtgac cggggccgcc gggaccgccc
    20881 tggccgggac cgccggagcc cccgggaccg ccgtggcccc agccgccggt gttgccgtgg
    20941 ccccagccac cgtggtcacc gccgcggccc cagcggcccc agccgtccca gttgccccag
    21001 ctgccgcgtc cccagcggcc gccccaggag ctgccgcccc agttgtggcc cgggttcccg
    21061 aagacacggc cgggaaggcc gtaccagcgg ccgggcaggc c
//
