LOCUS       NZ_JABBXA010000001     21068 bp    DNA     linear   CON 07-NOV-2024
DEFINITION  Microbispora sp. H13382 NODE_1, whole genome shotgun sequence.
ACCESSION   NZ_JABBXA010000001
VERSION     NZ_JABBXA010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora sp. H13382
  ORGANISM  Microbispora sp. H13382
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 845565)
  AUTHORS   Liu,C.
  TITLE     Selective isolation, identification and anti-microbial activity
            study of Microbispora
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 845565)
  AUTHORS   Liu,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-APR-2020) Microbiological Resources Collection Center,
            Sichuan Industrial Institute of Antibiotics, 168 Huaguan Road,
            Chengdu, Sichuan 610052, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014161445.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 07:22:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,982
            CDSs (total)                      :: 7,906
            Genes (coding)                    :: 7,786
            CDSs (with protein)               :: 7,786
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 21 of 121
            Pseudo Genes (incomplete)         :: 104 of 121
            Pseudo Genes (internal stop)      :: 8 of 121
            Pseudo Genes (multiple problems)  :: 11 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:45:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 594475
            Orig. end                         :: 615543
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABBXA010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21068
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="4"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21068
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21068
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11068](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11068)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            618..1931
                     /gene="allB"
                     /locus_tag="HHX41_RS02635"
     CDS             618..1931
                     /EC_number="3.5.2.5"
                     /GO_function="GO:0004038 - allantoinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0050897 - cobalt ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="allB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019633156.1"
                     /locus_tag="HHX41_RS02635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="allantoinase AllB"
                     /protein_id="WP_182904646.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 9.8e-26, bitscore:
                     86.3, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEPYDLVVRSRRTVTPEGERPLAVAVRGGVIAALCPYDDPPAAE
                     ESADLGELPLLPGLVDSHVHVNEPGRTHWEGFATATRAAAAGGVTTIVDMPLNSLPPTV
                     DVAALKVKRKAAEGRCHVDVAFWGGAIPGNLADLRPLHEAGVAGVKCFLSPSGVDEFPA
                     LDREGLRAALAEVAAFGGLLIAHAEDPGLLSDPRGPAYGDFLRSRPQEAERRAVEQVIA
                     LAAETGARAHIVHVSAAACVEPLRAAQAAGVRVTAETCPHYLTLAAEQVTGPAYKCCPP
                     IREAANRDALWRALADGVLMGIVSDHSPSTPDLKVPDFAAAWGGISSLQVGLPAVWTAA
                     RARGHGLTDVARWMAGGPARLAGLPHKGAIRVGDDADLVAFDPDAEFTVDVAALHHRNP
                     VSPYHGARLAGVVRTTWLRGVPVDFAAPRGRLLIRGAR"
     gene            1928..2893
                     /gene="alc"
                     /locus_tag="HHX41_RS02640"
     CDS             1928..2893
                     /EC_number="3.5.3.4"
                     /GO_function="GO:0004037 - allantoicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="alc"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541667.1"
                     /locus_tag="HHX41_RS02640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="allantoicase"
                     /protein_id="WP_182904647.1"
                     /transl_table=11
                     /translation="MTGFTRLPDLALRTYGGSVVAANDESFAEREALIRPGPAEFRPHT
                     FGAKGQVYDGWETRRRRAPGHDWAIVRLGLPGIIRGVVVDTAWFRGNYPPYASVEACAA
                     EGHPSPDELDGWVEIVPKSPLKGDAVHEFAVTDPRRFTHVRLNILPDGGVARLRVHGRV
                     VPDRAFLEGLTVDLAALENGGLVTACSDEFYSAPNNVLAPGLARDQSEGWETARRRDGG
                     NDWLVVALAGPGRVAVAEIDTANLIFNAPGWASLKGADADRAPLEDEDAWFPLLPRTRL
                     QPDTRHRFRLDDDHRVTHARLDIYPDGGLARLRLLGTLTP"
     gene            complement(3016..5025)
                     /gene="pknB"
                     /locus_tag="HHX41_RS02645"
     CDS             complement(3016..5025)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131588.1"
                     /locus_tag="HHX41_RS02645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_182904648.1"
                     /sec_met_domain="Pkinase (E-value: 4.5e-54, bitscore:
                     179.0, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 8.9e-08, bitscore: 27.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTTLTDPLVGQLLDGRYRVESRIARGGMASVYLALDVRLDRTVA
                     VKVMHRSLAEDPQFVRRFIGEAKSVASLSHPNIVQVFDQGTDGAHVYLSMEYVPGRTLR
                     DVLRGRGRLPAREALEMVIPVLAALGAAHQAGLIHRDVKPENVLLADDGRVKVVDFGLA
                     RAIEATNQTKTGMMIGTIGYMSPEQVTTGTADARSDVYAAGIMLFELLTGRQPYAGETP
                     MSIAYRHVHETVPAPSSIAHDVPPPIDALVAAATDKDPAARPADATAMLVAAVEIHRTL
                     PRTGHTGAHAAPYGAHDTGTHTSAHSGVRTGAHRTLPPPGGASPFGTSQHARPEAEPPV
                     GQTMIQPRSELLTGAGGAGRRRRARVRPVWFLASLALVMVAGIAFTGWWFSQGRYTTVP
                     DLVNQNITVARQEAQKAGFEVRIGKARFDDKVPKDIVLDTEPGAGAEVVKGAVLTLIPS
                     AGPETIPVPKVEGLSLADARAKVAEVGLTPGRVSKSASDTIPRDQVIRTNPPVGKRVKK
                     RGVVNFVVSAGLLMPDVTQMMRDQAEKILRDKGFNVQIDETTDDAPPGTVIAQDPSGGA
                     EVVAGATVHLTASRGPDQGFRWPWETDPADPGQTPPTVVNVPNVMFKSVHDAVNELKAA
                     GFKVNVRKVVGTDRVVGEKPLGQQPPGTTITIWH"
     gene            complement(5231..5995)
                     /locus_tag="HHX41_RS02650"
     CDS             complement(5231..5995)
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658554.1"
                     /locus_tag="HHX41_RS02650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiazole synthase"
                     /protein_id="WP_182904649.1"
                     /transl_table=11
                     /translation="MTDDVFVLGGEKFTSRLIMGTGGAPSLEVLDQALEASGTELTTVA
                     MRRLDPASRGSVLDVLRARGVKVLPNTAGCFTAGEAVLTARLAREALETDWVKLEVIAD
                     ERTLLPDPIETFDAAERLVADGFVVLPYIGDDPALARRLQDAGCAAVMPLGAPIGSGLG
                     IRNPHSIELIVEAATVPVILDAGIGTASDAALAMELGCDAVLLASAVTRAHRPDLMAAA
                     MRQAVTAGRLARLAGRIPRRRYAEASSPDRPS"
     gene            complement(5998..6198)
                     /gene="thiS"
                     /locus_tag="HHX41_RS02655"
     CDS             complement(5998..6198)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131590.1"
                     /locus_tag="HHX41_RS02655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_169978614.1"
                     /transl_table=11
                     /translation="MKVTINGGTAELPEGATVGDAVRTLTSLMSGVAVALNGEVVSRSA
                     WDSTQVADGDGVEVLTAVQGG"
     gene            complement(6195..7307)
                     /gene="thiO"
                     /locus_tag="HHX41_RS02660"
     CDS             complement(6195..7307)
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889486.1"
                     /locus_tag="HHX41_RS02660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_182904650.1"
                     /sec_met_domain="DAO (E-value: 6.5e-70, bitscore: 231.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPTYDVVIAGGGVAGLAAAWRTVRRGLSVAVADPAPGGGATHAS
                     AGMLAPVSEVTYTEEPLLRLGLASLAAWPHFRAELEDESGVELDYRTEGTLEVARGADD
                     MAYLDDLAAFERTLGLRVERLTGRECRSFEPMLAPSVRGGLLARDDAWVNPRRVVRALR
                     TAFEKAGGTLVADRVSGIDASGTGGASVRLASGEAVAAGQIVVAAGSWSASLLPGLPVR
                     PVKGEILRLRGPRGFLTRCVRGLVHGSPAYLVPRGDGEITLGATAQELGYDARVTAGGV
                     YELLRDARELVPGITELELTETTVGFRPGTPDNLPLIGPAGPPGVFAATGHGRNGVLLT
                     PITADAVAALLTGDEPPPVTGACHPGRFSK"
     regulatory      complement(7298..7408)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    7625..7645
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            7638..8816
                     /locus_tag="HHX41_RS02665"
     CDS             7638..8816
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853358.1"
                     /locus_tag="HHX41_RS02665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_182904651.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9.5e-52, bitscore:
                     171.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHVVVVGAGLAGVRSIEALRARGFTGRITLIGEEHHRPYDRPPL
                     SKAVLLGETDSTVVDSDLDALDVRLCLGTAAKGLRDGVLETTEGELEYDGLVIATGAAP
                     IRLRGEGRQHVLRTIEDALALRERLVPGARVAVVGAGWIGAEVATAAARAGCAVTVVEA
                     GESPLAVALGPAVGSHTIGWYARAGVELRLGAMVGTVDADGLTLMSGARVPADVVVTGV
                     GVRPAVDWLKGSAVRLDDGVVVDEHLRTSLPNVVAVGDCANWWSRRFRTRLRVEHWDTA
                     LQAPDTAVATLLGEEAVYDPVPYFWSEQFGHMVQFAGHREAGDRVLLRGDPRTDEKWAV
                     CWLTAEDTLAAVLTVDRPRDVVQGRRLVEGGQRLDPRRVADPAVPLRDCIMT"
     gene            8860..9234
                     /locus_tag="HHX41_RS02670"
     CDS             8860..9234
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131593.1"
                     /locus_tag="HHX41_RS02670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_169978608.1"
                     /transl_table=11
                     /translation="MTLTVAQIDRETDQLVGEWLPLSEAAKRLGLSMGRAKQLLKDKKL
                     AGARRGGGEPQIPAVFIAGGDVLKGLPGTLTLLADAGYDEVESIRWLFTPDDSLPGSPI
                     DAIVKGRHTEVKRRAQALGF"
     gene            9263..9916
                     /gene="thiE"
                     /locus_tag="HHX41_RS02675"
     CDS             9263..9916
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131594.1"
                     /locus_tag="HHX41_RS02675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_182904652.1"
                     /transl_table=11
                     /translation="MIDTRRQRLTQARLYLCTDGRRDRGDLEEFLDAVLSGGVDIVQLR
                     EKGLEAREELDLLEVFRAACDRHGALLAVNDRADVAFAARPDILHLGQDDLPVPVAREI
                     LGSGVLIGRSTHSAAEASAAAVEPGVDYFCCGPIWPTPTKPGRPAPGPALLEHAARLGT
                     DRPWFGIGGIDLGNLDEVMAHGVRRAVVVRAVTEADDPGAAAAALKARLSAVPL"
     gene            complement(10001..11068)
                     /locus_tag="HHX41_RS02680"
     CDS             complement(10001..11068)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131595.1"
                     /locus_tag="HHX41_RS02680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_182904653.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-50, bitscore:
                     167.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASAVSLDSIRTEVDRALREFLDRQRPHFGDPHLAALLTAAEDF
                     LAGGKRLRPAFCHWGWRAAGGGDDPGLHAAAASLELLQASALVHDDVMDASDVRRGMPS
                     AHRRFERMHTEAGWHGSARQFGEGSAVLLGNLLLVWSGEMWRTCGLAPEALAAAQPMHD
                     HMLTELMCGQYLDLLEQAQGESTYDSALRVALYKSGKYSVEQPLRLGLVLAARAPHAWI
                     DRLCVQYGQQVGIAFQLRDDILGVFGDPAETGKPAGDDLREGKRTVLIARALASATPAQ
                     AAVVRSLLGDPGLDAEGVGRLRAVIEETGALAACEDMIKRYLDDALHALDHAPIEEEAR
                     AALAGLAVAATSRRT"
     gene            11209..12138
                     /gene="metF"
                     /locus_tag="HHX41_RS02685"
     CDS             11209..12138
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131596.1"
                     /locus_tag="HHX41_RS02685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_169978602.1"
                     /transl_table=11
                     /translation="MALGLPSRLPDRVPTVRELLAAGERSFSFEFSPPKTDEGERQLWR
                     AIRELEALRPTFVSVTYGAGGSTRDRTVNIVERLAHETTLTPVAHFTAVDHSIRELRHL
                     VGRFADAGVRNILAVRGDPRGGNPLDEWVKHPEGVLYAEELVRLIRQAGDFCVGVAAFP
                     YKHPRSASIESDTEYFVQKCRAGADYAITQMFFRAEDYLRLRDRVAARGCDTPIIPGIM
                     PVTQMSTIARSEQLSGAPFPPEVAERFEAVADDPAAVRRLGIEHAVELCQKLLDEGAPG
                     IHFITFNRSSATREVFQALHSVPAAVAG"
     gene            complement(12153..12725)
                     /locus_tag="HHX41_RS02690"
     CDS             complement(12153..12725)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017617048.1"
                     /locus_tag="HHX41_RS02690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_169978600.1"
                     /transl_table=11
                     /translation="MIQLRRVGPDRFRAVLDTVLEIYTVAMRPPSDQLAGRMAIMRNHS
                     TYPDFDCMLAEDAQAPGGVAGFAYGFHGGHGQWWHDVVRGALQDRAGPVVAEDWFGDAL
                     EIAEIHVRPEYQGQGIGRRLIHTLCEGRPERTAVLSTHDAPTVARHLYRDVGFADLMTR
                     FVFPGGYEEYVIAGVRLPLPELGARES"
     gene            complement(12770..13246)
                     /locus_tag="HHX41_RS02695"
     CDS             complement(12770..13246)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131598.1"
                     /locus_tag="HHX41_RS02695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_169978598.1"
                     /transl_table=11
                     /translation="MAEKLHPNVVRVQEALRAHEVAGEVVVLDEAAPTAATAAARLGCE
                     VGAIANSLIFDADGAPLLVLTSGAHRVNTDLIARLVGAAKVRRATPEFVREHTGQPIGG
                     VAPVGHPAPVRTLVDTWLGKHSVVWAAAGHPHTVFPTSYEELLRITGGTAAEVE"
     misc_feature    13229..13245
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.72"
                     /tool="antismash"
     gene            13372..14214
                     /locus_tag="HHX41_RS02700"
     CDS             13372..14214
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131599.1"
                     /locus_tag="HHX41_RS02700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="L,D-transpeptidase family protein"
                     /protein_id="WP_259400563.1"
                     /transl_table=11
                     /translation="MMRGRRRLAAATLVAVGAVTFAVAGVTGTAQARTAAPAGAVTTAT
                     VPPALPALAALPARAAAYPPFTAPGKTLRLGAKGSAVKALQSRLQELGYMPGAADGRYG
                     GATLTAVWAFQKVQGIKPTSTIAARTWRALENPRAPRVLVPRGKPTRVEVDLTRQVMVL
                     YRGGAPVMISHISSGSGIPYTEYATWNGKRQRFSGSARTPTGDYTTTWRVKGWHRSYLG
                     QLYNPIFFNGGIALHGALSVPLYPASHGCVRLPMNVAEVLPGMLGRGVPVHVRGAFRR"
     misc_feature    13519..13521
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(14434..14450)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.34"
                     /tool="antismash"
     misc_feature    complement(14457..14472)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.27"
                     /tool="antismash"
     misc_feature    14458..14471
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.72"
                     /tool="antismash"
     misc_feature    14459..14470
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.53"
                     /tool="antismash"
     misc_feature    14488..14501
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.17"
                     /tool="antismash"
     misc_feature    14497..14512
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.49"
                     /tool="antismash"
     misc_feature    complement(14498..14511)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.0"
                     /tool="antismash"
     gene            14781..15218
                     /locus_tag="HHX41_RS02705"
     CDS             14781..15218
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853345.1"
                     /locus_tag="HHX41_RS02705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_142556683.1"
                     /transl_table=11
                     /translation="MTEENDDQKSGPRLSQAVLAHLADARACLADATVGPTPADRYVSA
                     HLAALRAAAGILAARPRPMDGRRRRLRSAWELLPEAEPKLADWAAYFAVSATKRAAAEA
                     GMVRAVTQNDAEEIIAEADRFVGEVESILGLPGRPTLPMAG"
     gene            complement(15402..16646)
                     /locus_tag="HHX41_RS02710"
     CDS             complement(15402..16646)
                     /EC_number="3.5.3.6"
                     /GO_function="GO:0016990 - arginine deiminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889503.1"
                     /locus_tag="HHX41_RS02710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="arginine deiminase"
                     /protein_id="WP_169978596.1"
                     /transl_table=11
                     /translation="MTFYVGSEVGRLRRVLVDIPELALKRLTPGNKDGLLFDDVLWVHR
                     ALEEHREWCDVLAGRGVTVHHLGDLLREVIEIPDARKHILDGSVDEHWFGPLTADAIRN
                     TLDSLDADALAPLLTGGITKREIMELGCDPGSITFHTLAMDDFVLPPLPNHLFARDTSC
                     WVYDGVSINAMRKKARRRETVNYEAVYRWHPLFAAGYGNPDDGGFNVWYEGVRMAPATI
                     EGGDVLVLGGGVVLVGVSERTQPQAVEMLATNLFRAGSATRIVALDLPKTRAFMHLDTV
                     MTNVDVGVFTKYAGLGMLPSYTVEPGDTDKELKVTDHPPEDMHKAIARALGLDDIKVLT
                     PTQDVHAAEREQWDDGCNVLALEPGVVVAYERNTTTNNHLRRHGIEVIPIRGSELGRGR
                     GGPRCMSCPLERDPV"
     gene            complement(16782..17276)
                     /locus_tag="HHX41_RS02715"
     CDS             complement(16782..17276)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622275.1"
                     /locus_tag="HHX41_RS02715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcriptional regulator"
                     /protein_id="WP_030508976.1"
                     /transl_table=11
                     /translation="MPSDYAKSLGARLRAIRTQQGLSLHGVEEKSRGRWKAVVVGSYER
                     GDRAVTVQKLAELADFYGVPVSELLPGGAAPSPLAPAPKLVIDLERLSQLPKDKAGPLA
                     RYAATIQSQRGDYNGKVLSIRQEDLRSLAVIYDKSPVELTEEFIHWGVLDAEARRAVES
                     F"
     misc_feature    complement(17471..17486)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.71"
                     /tool="antismash"
     gene            17712..18269
                     /gene="pyrR"
                     /locus_tag="HHX41_RS02720"
     CDS             17712..18269
                     /EC_number="2.4.2.9"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131602.1"
                     /locus_tag="HHX41_RS02720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="WP_169978594.1"
                     /transl_table=11
                     /translation="MSDARNPARAVLEGPDIHRALTRIAHEILERTRGAESVVLIGIPT
                     RGATLAQRIAGRIAQFEGIKVPVGAIDVTMYRDDLRLRPARPLGRTELPPDGVDGRTVV
                     LVDDVLYSGRTVRAALDALNDVGRPRAVQLATLVDRGHRELPIRADYVGKNLPTSKSEK
                     VKVFLEETDGRDAVVLIKEDDR"
     gene            18266..19201
                     /locus_tag="HHX41_RS02725"
     CDS             18266..19201
                     /EC_number="2.1.3.2"
                     /GO_function="GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016597 - amino acid binding [Evidence
                     IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131603.1"
                     /locus_tag="HHX41_RS02725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate carbamoyltransferase catalytic subunit"
                     /protein_id="WP_169978592.1"
                     /transl_table=11
                     /translation="MKRHLISTGDLTRDDALLILDTAEELAQVSQRSIKKLPTLRGRTV
                     VNLFFEDSTRTRISFEAAAKRLSADVINFSAKGSSVSKGESLKDTALTLEAMGADAVVI
                     RHSASGAPHRLANWVRGSVVNAGDGTHEHPTQALLDAFSIRRRLGRLEGLKIAIVGDVL
                     HSRVARSNVLLLHTLGAEVTLVAPPTLLPVAVGTWPCQVSYDLDAVLPKSDVVMMLRVQ
                     LERMNAAYFPSAREYSRRYGLDRDRFARLHDDAVVMHPGPMNRGMEISAEVADSPRSTI
                     VEQVTNGVTVRMAVLYLLLGGSEPAIGGAE"
     gene            19231..20532
                     /locus_tag="HHX41_RS02730"
     CDS             19231..20532
                     /EC_number="3.5.2.3"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131604.1"
                     /locus_tag="HHX41_RS02730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydroorotase"
                     /protein_id="WP_182904654.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 3.1e-15, bitscore:
                     51.7, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTILIRGARILGGAPSDILLRDGVVAETGDLAGARADQTVDADG
                     LVALPGLVDLHTHLREPGREDAETVETGTQAAARGGYTAVHAMANTSPVADTAGVVEQV
                     WRLGQEHGHCDVQPVGAVTSGLQGRQLAELGAMADSAARVRVFSDDGKCVSDAVLMRRA
                     LEYVKAFDGVVAQHAQEPRLTEGAQLNEGEVSARLGLTGWPAVAEEAIIARDCLLAAHV
                     GSRLHVCHVSTAGSVEIIRWAKSKGWDVTAEVTPHHLLLTDSCAERSPLGPYNPIYKVN
                     PPLRTAEDVRALREALADGTIDCVATDHAPHPVEDKETEWAAAAMGMIGLETALSVVQE
                     AMVETGLLDWAGVADRMSARPARIGRLTGHGRPIEPGAPGNVTLYDPSGRQPVDPAAMV
                     SKSRNTPYEGLTLPGRVVATFLRGRPTVLEGKLV"
ORIGIN
        1 gatcgtggcg agcgacgtgg acaacccgct gctcgggccg tacggcgcgg cggcggtgta
       61 cggcccgcag aagggggcga gcccgcagga cgtggccgtg ctggaggccg ggctggcccg
      121 gctggcggcc gtggccgcgc acacccacgg cctcgcgggc gccgccgagc acgacggcgt
      181 ggtccgtgcg atgggcgtgg ccgggcggcc gggggccggg gccgcgggcg gggtgggctt
      241 cggcgcgctg acgttcctga acgccgagat ccggccgggc atcggctatc tgctggacct
      301 cgaggagttc gaccggcacg tcgagggcgc ccggctggtc gtcaccggtg agggttcgat
      361 cgacgagcag accctgcgcg gcaaggcccc ggtgggcgtc gcggcggcgg cggccaagca
      421 cggcgtgccg gtcgtcgcgg tctgcggccg gcggtcggtg ggcgacgacg agttgcgggc
      481 ggccggcatc gaggcggcgt acgcgctgac cgacgtcgag cccgacgtga gccgctgcat
      541 ggccgaggcc gggccgctgc tggagaagct cgcggcgcgg gtcgccgcct ggcatctcac
      601 gacatgagga gtggcgcgtg ggggaaccgt acgacctggt ggtgaggtcc cggcggaccg
      661 tgaccccgga gggggagcgt ccgctcgcgg tcgccgtacg cgggggtgtg atcgccgccc
      721 tgtgtcccta cgacgatcca ccggcggcgg aggagtccgc cgacctcggc gaactgccgc
      781 tgctgcccgg gctggtcgat tcccacgtgc acgtcaacga gcccggccgt actcactggg
      841 agggcttcgc gaccgccacc agagcggcgg cggccggggg cgtgaccacc atcgtggaca
      901 tgccgctcaa ctcgctgccc ccgaccgtgg acgtggcggc gctgaaggtc aagcggaagg
      961 ccgccgaggg gcggtgccac gtggacgtcg ccttctgggg tggtgcgatc cccggcaacc
     1021 tcgccgacct gcggcccctg cacgaggccg gtgtggcggg cgtcaagtgc ttcctttcgc
     1081 cgtccggggt ggacgagttc ccggcgctcg accgcgaggg gctgcgggcc gcgctggcgg
     1141 aggtggcggc cttcggcggc ctgctgatcg cgcacgccga ggaccccggc ctgctgtccg
     1201 acccccgcgg cccggcgtac ggcgacttcc tcaggtcgcg cccccaggag gccgagcgca
     1261 gggccgtcga gcaggtgatc gccctcgcgg cggagacggg cgcgcgggcg cacatcgtgc
     1321 acgtgtcggc cgccgcctgc gtcgaaccgc tgcgcgcggc gcaggcggcg ggggtgcgcg
     1381 tcaccgccga gacctgcccc cactatctga ccctggcggc ggagcaggtc accgggcccg
     1441 cgtacaagtg ctgcccgccg atccgggagg ccgccaaccg cgacgcgctg tggcgggcgc
     1501 tcgccgacgg ggtgctcatg gggatcgtct ccgaccactc cccgtcgacg cccgacctca
     1561 aggtgcccga cttcgccgcg gcctggggcg ggatctcctc gctccaggtc ggcctgcccg
     1621 ccgtgtggac ggcggctcgc gcccggggcc acggcctgac cgacgtggcg cgctggatgg
     1681 ccgggggacc ggcccgcctg gccggcctgc cgcacaaggg ggcgatccgg gtgggcgacg
     1741 acgcggacct ggtcgccttc gaccccgacg cggagttcac cgtcgacgtg gcggcgctcc
     1801 accaccgcaa cccggtgtcc ccttaccacg gcgcgcggct cgcgggcgtc gtacgcacca
     1861 cctggctgcg cggcgtgccc gtcgacttcg ccgccccgcg cggacgactg ctgatccgag
     1921 gagcgcgatg accggcttca cccgcctgcc cgacctcgcc ctgcgcacgt acggcgggtc
     1981 ggtcgtggcc gcaaacgacg agtcgttcgc cgaacgggag gccctgatca ggccggggcc
     2041 ggccgagttc cggccgcaca ccttcggcgc caagggccag gtctacgacg gctgggagac
     2101 ccggcggcgg cgtgcgcccg gccacgactg ggcgatcgtc cggctcggcc tgccgggcat
     2161 catccggggc gtggtggtgg acaccgcgtg gttccgcggc aactacccgc cgtacgcgtc
     2221 ggtcgaggcg tgcgcggccg agggccaccc ctcgccggac gagctggacg gctgggtgga
     2281 gatcgtgccg aagagcccgc tgaagggtga cgcggtccac gagttcgccg tgaccgaccc
     2341 ccgccgtttc acgcacgtgc ggctgaacat cctccccgac ggcggcgtcg cgcggctgcg
     2401 ggtccacggg cgggtcgtac ccgaccgcgc tttcctggag ggcctcaccg tcgacctcgc
     2461 cgcgctggag aacggcggcc tggtcacggc ctgctccgac gagttctact ccgcgccgaa
     2521 caacgtcctc gcgcccggcc tggcccgcga ccagtccgag ggctgggaga ccgcgcgccg
     2581 ccgcgacggc ggcaacgact ggctcgtggt cgccctggcc gggccgggcc gggtggccgt
     2641 cgccgagatc gacacggcca acctgatctt caacgccccc ggctgggcgt cgctgaaggg
     2701 cgcggatgcg gaccgggcgc cgctggagga cgaggacgcc tggttcccgc tgctgcccag
     2761 gacccgcctg cagcccgaca cccgtcaccg cttccgcctc gacgacgacc acagggtcac
     2821 ccacgcccgg ctcgacatct accccgacgg cggcctcgcc cgcctccgcc tcctcggcac
     2881 cctcaccccc tgagccatct cggcgacgac ctctacatcc tcaggggagc cgatcccgac
     2941 gccgcctgac gccggtcggg gcgcgacgac ggccacgagt ggtggccgta cgcgaccgga
     3001 tgaccggcgg gggcgtcagt gccagatcgt gatggtggtg cccggcggct gctgaccgag
     3061 cggcttctca ccgaccacgc ggtcggtgcc caccaccttg cggacgttga ccttgaaacc
     3121 ggccgccttc agctcgttca ccgcgtcgtg gacggacttg aacatcacgt tgggcacgtt
     3181 gacgacggtg ggcggggtct ggccggggtc ggcggggtcg gtctcccacg gccagcggaa
     3241 gccctggtcc gggccgcgcg aggccgtcag gtggacggtc gccccggcca ccacctcggc
     3301 gccgccggac gggtcctggg cgatcaccgt gcccggcggg gcgtcgtcgg tggtctcgtc
     3361 gatctggacg ttgaagccct tgtcgcgcag gatcttctcc gcctggtcgc gcatcatctg
     3421 cgtgacgtcc ggcatcagaa gtcccgcgct gacgacgaag ttgaccacgc cgcgcttctt
     3481 gacgcgcttg cccaccggcg ggttggtacg gatgacctgg tcgcggggga tggtgtcgct
     3541 cgcgctcttg ctgacccggc cgggggtcag cccgacctcg gcgaccttcg cccgggcgtc
     3601 cgccaggctc aggccctcga ccttcggcac ggggatcgtc tccgggccgg ccgacgggat
     3661 cagggtgagg acggcgccct tgaccacctc ggcgcccgcg ccgggctcgg tgtcgaggac
     3721 gatgtccttc ggcaccttgt cgtcgaacct cgccttgccg atccgtacct cgaagccggc
     3781 cttctgcgcc tcctgcctgg cgaccgtgat gttctggttc accagatcgg gcacggtcgt
     3841 gtagcgcccc tgggagaacc accaaccggt gaaggcgatg cccgccacca tgacgagggc
     3901 cagcgaggcg aggaaccaca cgggcctgac cctggcccgt cgccgccggc ccgctccacc
     3961 ggcgccggtc agcagttccg agcgcggctg gatcatcgtc tggccgaccg gcggctcggc
     4021 ctccgggcgc gcgtgctgcg acgtgccgaa cggcgaggcc ccgccgggcg gcgggagggt
     4081 ccggtgcgca cccgtccgta cgccgctgtg ggcgctggtg tgggtgccgg tgtcgtgggc
     4141 tccgtaaggg gcggcgtgcg cgccggtgtg cccggtccgc ggcagcgtgc ggtggatctc
     4201 gacggccgcg acgagcatgg cggtcgcgtc cgccgggcgc gcggcggggt ccttgtcggt
     4261 ggccgccgcg acgagcgcgt cgatcggcgg cggcacgtcg tgcgcgatcg aggacggcgc
     4321 ggggacggtc tcgtgcacgt gccggtaggc gatcgacatc ggcgtctcgc ccgcgtacgg
     4381 ctgccgcccg gtcagcagct cgaacagcat gatcccggcg gcgtacacgt cgctgcgggc
     4441 gtcggcggtg ccggtcgtga cctgctcggg cgacatgtag ccgatcgtgc cgatcatcat
     4501 gccggtcttg gtctggttgg tcgcctcgat cgcgcgggcc aggccgaagt ccacgacctt
     4561 cacccggccg tcgtcggcga gcagcacgtt ctccggcttg acgtcccggt ggatgagccc
     4621 cgcctggtgg gccgcgccga gggcggcgag caccgggatg accatctcca gcgcctcgcg
     4681 cgccgggaga cggccgcgcc cgcgcagcac gtcgcgcagc gtccgcccgg gcacgtactc
     4741 catcgacagg tagacgtgcg ccccgtccgt gccctggtcg aagacctgca cgatgttcgg
     4801 gtgcgagagg ctcgccaccg acttggcctc gccgatgaac cgccgcacga actgcgggtc
     4861 ctcggccagc gagcggtgca tcaccttgac ggccaccgtg cggtcgagcc ggacgtccag
     4921 agcaagatat acggaggcca tgccaccccg ggcgatccgg gactcgacgc ggtagcgccc
     4981 gtcgagcaac tgccccacga gcgggtcggt cagcgtcgtg tccactcgcc agagtttacg
     5041 ggtgatttgc cgccgggcgt gttcccgaat cccaaaccga gacctattcg gcagccctcc
     5101 gcgccgcccg aaaagccgtg tctaatccga aaaccgggct taccagacgc ggattcccgc
     5161 acctctccgc ccgccggcgc gaacacgccg gacgggcggg ggacgccttt gtgtggtgga
     5221 cgcggcgggc tcaggacggg cggtcggggg aggacgcctc ggcgtagcgg cggcggggga
     5281 tgcgccccgc gagcctggcc agccgcccgg ccgtgaccgc ctgccgcatg gccgccgcca
     5341 tcaggtccgg ccggtgcgcc cgcgtcacgg cgctggccag cagcacggcg tcgcagccca
     5401 gctccatcgc cagcgcggcg tcgctggccg tgccgatgcc ggcgtcgagg atcaccggga
     5461 ccgtggcggc ctcgacgatc agctcgatgc tgtgcgggtt gcggatgccc agtccggagc
     5521 cgatgggggc gccgagcggc atcaccgccg cgcacccggc gtcctggagc ctgcgggcca
     5581 gcgccgggtc gtcgccgatg tacggcagca cgacgaagcc gtcggcgacc agccgctcgg
     5641 cggcgtcgaa ggtctcgatc gggtcgggca gcagggtgcg ctcgtcggcg atgacctcca
     5701 gcttgaccca gtcggtctcc agggcctcac gcgccaggcg ggcggtcagc acggcctccc
     5761 cggccgtgaa gcaccccgcg gtgttcggca gcaccttgac gccgcgggcg cgcagcacgt
     5821 ccagcaccga accgcgcgac gccgggtcga gcctgcgcat cgcgacggtc gtcagttcgg
     5881 tgccggacgc ctccagcgcc tggtcgagca cctccagcga cggcgcgccg ccggtgccca
     5941 tgatgagccg cgaggtgaac ttctccccgc ccagcacgaa gacgtcgtcg gtcatgctca
     6001 tcctccctgc accgccgtca gcacctcgac gccgtcgccg tcggccacct gagtggagtc
     6061 ccaggcgctc cggctcacca cctcgccgtt cagggccacc gcgaccccgg acatgaggga
     6121 cgtgagggtc cgtacggcgt cgccgaccgt ggcgccctcg ggcagctcgg ccgtgcctcc
     6181 gttgatcgtg actttcactt gctgaatctc cctggatggc aggccccggt gaccgggggt
     6241 ggctcgtcgc cggtgaggag cgccgcgacg gcgtcggcgg tgatcggggt cagcagcacg
     6301 ccgttgcggc cgtgcccggt cgccgcgaac acgccgggcg ggccggcggg gccgatgagc
     6361 ggcaggttgt cgggcgtgcc cgggcggaag ccgaccgtgg tctcggtcag ttcgagctcg
     6421 gtgatgccgg gcaccagctc gcgggcgtcg cgcagcagct cgtacacgcc gccggcggtg
     6481 acccgcgcgt cgtaccccag ctcctgcgcc gtggcgccca gcgtgatctc tccgtcgccc
     6541 cggggcacca ggtaggcggg ggagccgtgc accagccccc gtacgcaccg cgtgaggaac
     6601 ccccggggcc cgcgcagccg gaggatctcg cccttgaccg ggcgtaccgg caggccgggc
     6661 agcagggacg ccgaccacga tcctgccgcc acgacgatct ggcccgccgc gacggcctcg
     6721 ccggacgcca gccgtacgga cgcaccgccc gtccctgagg cgtcgatccc ggagacgcgg
     6781 tcggcgacca gcgtgccgcc cgccttctcg aacgcggtgc gcagggcccg cacgaccctg
     6841 cgcgggttga cccaggcgtc gtcgcgggcc agcagcccgc cgcgtacgga gggggcgagc
     6901 atcggctcga aggaacggca ctcgcgcccg gtgagccgct cgacccgcag gccgagcgtc
     6961 cgctcgaagg ccgccaggtc gtccagatag gccatgtcgt ccgcgccgcg ggcgacctcc
     7021 agcgtgccct cggtccggta gtccagctcg acgccgctct cgtcctcgag ttcggcgcgg
     7081 aagtgcggcc aggccgccag cgacgcgagg ccgagccgca gcagcggctc ctccgtgtag
     7141 gtcacctcgc tgaccggcgc gagcatcccg gccgaggcgt gggtggcgcc gcctccgggc
     7201 gcggggtccg ccaccgccac cgacaggccc cggcgaaccg tgcgccaggc cgcggccagg
     7261 ccggccacgc cgccgccggc gatcacgacg tcgtatgtgg ggggcacacc gcgctccctt
     7321 cgccggcatt acccggatca ggtcggggcg gtcgagagcc tcccgctctc ctctcagccc
     7381 ggtccgccgg gctcccgcgc gtcttacgcc caccagcgta gtacgccgcc cgtcatggcc
     7441 gatcgccggc ggccgtccgc cgccacctgg caggcggacg ccgcgtgccg cgcgcgacga
     7501 agatccgcac gcgcgtcgtc cggtggagta agggcctcct tcacaacgtg ggcccccggg
     7561 gaagtgcgcg ctacttgccc aactcgttat gaggggcccg ttggccaggg cccccgctga
     7621 caatctatgg tcaagctgtg gatcacgtcg tggtggtggg tgccggcctg gccggcgtgc
     7681 gaagcatcga ggcgttgagg gcccgtggat tcaccggccg catcacgctc atcggcgagg
     7741 aacaccatcg cccctatgac cggccgccgc tgtcgaaggc ggtgctgctc ggagagaccg
     7801 actccacggt ggtcgactcc gacctcgacg ccctcgacgt acggctgtgc ctcggcacgg
     7861 cggccaaggg cctgcgcgac ggcgtgctgg agacgaccga gggcgagctg gagtacgacg
     7921 gcctggtcat cgccaccggc gccgccccga tccgcctgcg cggcgagggc cgccagcacg
     7981 tgctgcgcac catagaggac gcgctggcgc tgcgcgagcg gctggtcccc ggcgcccgcg
     8041 tggccgtggt cggagccggc tggatcggcg cggaggtcgc caccgccgcg gccagggccg
     8101 ggtgcgcggt gaccgtcgtg gaggcggggg agagcccgct cgccgtggcg ctcggccccg
     8161 ccgtcggcag ccacaccatc ggctggtacg cgcgggcggg cgtcgaacta cgcctcggcg
     8221 cgatggtcgg caccgtggac gccgacggcc tcacgctcat gtccggcgcc cgggtgccgg
     8281 cggacgtggt cgtcaccggc gtcggggtgc gccccgcggt cgactggctg aagggctcgg
     8341 ccgtccggct cgacgacggg gtggtggtcg acgagcacct gcgcacgtcg ctgcccaacg
     8401 tcgtcgcggt gggggactgc gccaactggt ggtcgcgcag gttccgcacc cgcctgcggg
     8461 tcgagcactg ggacaccgcg ctccaggctc ccgacacggc cgtcgccacc ctcctgggcg
     8521 aggaggcggt ctacgacccc gtgccgtact tctggtcgga gcagttcggc cacatggtgc
     8581 agttcgccgg gcaccgggag gccggtgacc gggtgctgct gcgcggcgac ccgcgtacgg
     8641 acgagaagtg ggcggtgtgc tggctgacgg ccgaggacac gctcgccgcg gtgctcaccg
     8701 tggaccggcc gcgcgacgtg gtgcagggtc gcaggctcgt cgagggcggc cagcggctcg
     8761 accctcggcg ggtggccgac ccggccgtcc cgctccgcga ctgcattatg acgtaatcga
     8821 ggtgtttcct ggcggcccgc ctgtggtaat ggtggttccg tgacgcttac tgttgcgcag
     8881 atcgaccggg agaccgacca gctcgtaggg gagtggctcc ccctctcgga ggccgccaag
     8941 aggctggggc tcagcatggg ccgcgccaag caactcctca aggacaagaa actcgccggc
     9001 gcccgcaggg gcgggggcga gccgcagatc cccgcggtgt tcatcgccgg cggcgacgtg
     9061 ctcaagggcc tgcccggcac gctgacgctc ctggccgacg cggggtacga cgaggtggag
     9121 tcgatccggt ggctgttcac cccggacgac tcgctgccgg ggtccccaat cgacgcgatc
     9181 gtgaagggcc ggcacaccga ggtcaagcgc agggcccagg ccctgggttt ctgaccgtac
     9241 ggccccatgg cattgtggtc gggtgattga cacccggcga cagcggctca cgcaggccag
     9301 gctctacctc tgcaccgacg gcaggaggga ccgcggcgac ctggaggaat tcctcgacgc
     9361 ggtcctgtcc ggcggagtgg acatcgtcca gctcagggag aagggcctgg aggcgcgcga
     9421 ggagctggac ctgctcgagg tcttccgcgc ggcgtgcgac aggcacggtg cgctgctggc
     9481 cgtcaacgac cgggcggacg tcgccttcgc cgcccggccc gacatcctgc acctcgggca
     9541 ggacgacctc ccggtcccgg tggcccggga gatcctcggc tccggcgtgc tcatcggcag
     9601 gtccacgcac tcggcggcgg aggcgtcggc cgccgccgtg gagccggggg tggactactt
     9661 ctgctgcggg ccgatctggc ccacgcccac caaacccggc cgcccggcgc ccggccccgc
     9721 gctgctggaa cacgcggcgc gcctgggcac cgaccggccg tggttcggca tcggcggcat
     9781 cgacctgggc aacctcgacg aggtgatggc gcacggcgtg cgccgggcgg tggtcgtccg
     9841 ggccgtcacc gaggccgacg acccgggcgc cgccgccgcc gcgctcaagg cccggctgtc
     9901 cgccgtcccg ctctgagccg cctctgagcc ccccgtgcgc cgcgtcccgt cacgcgggac
     9961 gcggcgcacg gggggccgcc accggtcctg ccccgcgccg tcaggtgcgg cgggacgtgg
    10021 cggcgacggc gaggccggcc agcgccgcgc gggcctcctc ctcgatcggc gcgtggtcga
    10081 gggcgtgcag cgcgtcgtcg agataacgct tgatcatgtc ctcgcacgcg gccagcgcgc
    10141 cggtctcctc gatcaccgcg cgcagccgcc cgacgccctc ggcgtccagc ccggggtcgc
    10201 cgagaaggga ccgtacgacc gccgcctggg cgggggtggc cgaggcgagc gcgcgcgcga
    10261 tcaggacggt ccgcttgccc tcgcgaaggt cgtccccggc gggcttgccg gtctccgcag
    10321 ggtcgccgaa cacgccgagg atgtcgtcgc ggagctggaa ggcgatgccc acctgctggc
    10381 cgtactgcac gcagagccgg tcgatccacg cgtgcggggc ccgggcggcg aggacgagtc
    10441 cgagccggag cggctgctcg accgagtact tgccgctctt gtagagggcc acccgcagcg
    10501 cgctgtcgta ggtgctctcg ccctgagcct gttcgagcag atcgagatac tgcccgcaca
    10561 tcagctcggt gagcatgtgg tcgtgcatcg gctgcgcggc ggcgagcgcc tcgggcgcca
    10621 ggccgcaggt gcgccacatc tccccggacc acaccagcag caggttcccc agcagcacgg
    10681 ccgagccctc gccgaactgc cgcgcggagc cgtgccagcc cgcctcggtg tgcatccgct
    10741 cgaatcggcg gtgcgcggac ggcatgcccc ggcgcacgtc gctcgcgtcc atgacgtcgt
    10801 cgtggacgag cgcgctcgcc tgcagcagct ccagcgaggc ggcggcggcg tgcagccccg
    10861 ggtcgtcgcc gccgccggcg gcccgccacc cccagtggca gaaggcgggg cgcagccgtt
    10921 tgccgccggc caggaagtcc tccgcggcgg tcagcagggc ggccagatga gggtcaccga
    10981 agtgtggtcg ctgccggtcg aggaactccc ggagtgcgcg gtccacctcc gtacggatgg
    11041 aatcgagcga gacggcggaa gcggtcatgc tctgagagta accggggttg atccggacac
    11101 acatcaccag atcccccttc aagtgggtta actcacccag taagggaaaa cgtccacata
    11161 gcaagactgc gaccatcggg aaaagtgcgg cgctgtaacc tctcctgtat ggctctcggt
    11221 ctgccctcgc ggcttcctga tcgcgtcccg acggtccgcg aactgctggc cgcgggcgag
    11281 cgctcgttct cgttcgagtt ctccccgccg aagaccgacg agggggagcg ccagctgtgg
    11341 cgggccatcc gcgagctcga ggcgctgcgg ccgacgttcg tctccgtgac ctacggcgcc
    11401 ggcggctcga cccgcgaccg caccgtgaac atcgtcgagc ggctggcgca cgagacgacg
    11461 ctgacccccg tcgcccactt caccgcggtc gaccactcga tccgcgagct gcgccacctc
    11521 gtcggccggt tcgccgacgc gggcgtgcgc aacatcctcg ccgtacgcgg cgacccgcgc
    11581 gggggcaacc ccctggacga gtgggtcaag cacccggagg gcgtgctgta cgccgaggag
    11641 ctggtgcgcc tgatccgcca ggcgggcgac ttctgcgtgg gggtggccgc attcccgtac
    11701 aagcacccca ggtcggcgag catcgagtcg gacaccgagt atttcgtgca gaagtgccgg
    11761 gccggcgcgg actacgcgat cacccagatg ttcttccggg cggaggacta cctgcggctg
    11821 cgtgaccgcg tggcggcccg tgggtgtgac acccccatca tccccggcat catgcccgtc
    11881 acgcagatga gcacgatcgc ccggtcggag cagctgtccg gcgcgccgtt cccgcccgag
    11941 gtggccgagc ggttcgaggc cgtcgccgac gacccggccg cggttcgccg cctcgggatc
    12001 gagcacgccg tcgagctgtg ccagaagctg ctcgacgagg gcgcgcccgg catccacttc
    12061 atcaccttca accggtcgag cgcgacccgc gaggtgttcc aggcgctgca cagcgtgccc
    12121 gcggccgtcg ccggctgagc cggccggtcc gttcagctct cgcgggcccc gagctcgggc
    12181 agcggcagcc gcaccccggc gatgacgtac tcctcgtatc cgccggggaa gacgaaccgg
    12241 gtcatcaggt cggcgaaccc gacgtcccgg tagagatgcc gggccaccgt gggggcgtcg
    12301 tgcgtcgaga gcacggccgt acgctccggg cggccctcgc acagcgtgtg gatcaggcgc
    12361 cgcccgatcc cctggccctg gtactcgggg cgcacgtgga tctcggcgat ctccagggcg
    12421 tcgccgaacc agtcctccgc caccaccggc ccggcccggt cctgcagcgc cccgcgtacg
    12481 acgtcgtgcc accactgccc atggccgccg tggaagccgt acgcgaagcc ggcgacgccg
    12541 ccaggagcct gcgcgtcctc ggcgagcatg cagtcgaagt cgggataggt ggagtggtta
    12601 cgcatgatcg ccatgcgccc cgcgagctgg tccgacggcg ggcgcatggc gaccgtgtaa
    12661 atctccagaa cggtgtccag caccgccctg aaccggtcgg gccccacccg tcgcagttgg
    12721 atcactcgtc gcacattagc aaaacgtcgc cgggccggtc cggcaggcgt cactccacct
    12781 cggcggccgt gcccccggta atgcgcagca actcctcgta ggacgtgggg aagaccgtgt
    12841 gggggtgccc cgcggcggcc cacaccacgc tgtgcttgcc cagccaggtg tccacgagcg
    12901 tccgtacggg cgcggggtgc ccgaccgggg cgacgccgcc gatgggctgc ccggtgtgct
    12961 cgcggacgaa ctccggcgtg gcccgccgca ccttcgccgc gccgacgagc cgcgcgatca
    13021 ggtcggtgtt cacgcggtgg gcgccgctgg tgagcaccag cagcggcgcg ccgtccgcgt
    13081 cgaagatcag gctgttcgcg atcgcgccca cctcgcagcc gagccgggcc gccgcagtgg
    13141 cggcggtcgg ggcggcctcg tccagcacga cgacctcgcc cgccacctcg tgggcccgca
    13201 gggcctcctg gactcggacg acgttcggat gcaacttttc tgccacgcgg tcactctaaa
    13261 cggattgcca ggacatacgc cgccgattat ggccacttaa gatcaagcgg ctcacaatcg
    13321 gaccgtaagg tgggtccttt gatcgggaat cgggcttatg aggggttggt catgatgagg
    13381 ggtcgacggc gactggccgc ggccacgctc gtcgcggtgg gggccgtgac gttcgcggtg
    13441 gccggcgtca ccggcacggc gcaggcgcgc accgccgcgc ccgcgggagc ggtgaccacg
    13501 gcgaccgtgc cgccagcgtt accggcgctc gcggcgctcc cggcgcgcgc cgccgcctat
    13561 ccgccgttca ccgcgccggg caagacgctc aggctcggcg ccaagggctc ggccgtgaag
    13621 gcgctgcagt cccggctcca ggagctcgga tacatgcccg gcgcggccga cggccggtac
    13681 ggcggggcca cgctgacggc ggtctgggcg ttccagaagg tgcaggggat caagccgacc
    13741 agcacgatcg ccgcccgcac ctggagggcg ctggagaacc cccgcgcgcc cagggtcctg
    13801 gtgccccggg gcaagccgac gcgcgtcgag gtggacctga ccagacaggt gatggttctg
    13861 taccggggcg gcgcgccggt gatgatcagc cacatctcca gcggcagcgg catcccctac
    13921 accgagtacg ccacctggaa cggcaagcgg cagcggttct ccggcagcgc ccgcacgccg
    13981 accggcgact acacgaccac ctggcgggtc aagggctggc accggtccta cctcgggcag
    14041 ctctacaacc cgatcttctt caacggcggc atcgcgctcc acggcgccct gtcggtgccg
    14101 ctctacccgg cgtcgcacgg ctgcgtgcgg ctgcccatga acgtggccga ggtcctgccg
    14161 ggcatgctcg gcaggggcgt cccggtgcac gtcaggggtg ccttcaggcg ctagtgcccc
    14221 tcccgccaac ctttgccccg tcgcgtcgcc cagagcggca cctcgctgcg ttgtcgtcgt
    14281 cgctcgtagc tccgctacga gctcctcctc cgccttgcga tgcaccactc tggccaccgc
    14341 tccgtccggg caaactttgg cggtcgcggc accagttcca cccccggagg ggccccgcgc
    14401 gaggtgctcg cgcggggccc ctccgccgtc tcgtgcccac gtttgcgcca cactcctcga
    14461 acacgtattc gttgacagcc ttgacagtgg acatgatcga atctatgttc gatggagtgg
    14521 gcgtgggact cgcggctcgc gcccaccccg ttggaatcgt gccttcgtcg tcggcggaga
    14581 cggatgcggc acggcccgcg gcgtgggccg gacggggaga ggggaagctc ctcgtccggc
    14641 cgcccacggg agcctgagaa agcgtcgggc gatctcgagc ggttcacggg atctcccggc
    14701 cggcgaaatt gtcggtgcga tctgcgactg tgagatcacc ggcgaccttc gccggagtgc
    14761 cacgactcaa ggaggcgggc atgactgagg agaacgacga tcagaagagc gggccccggc
    14821 tctcgcaggc ggttctggca cacctcgcgg acgccagagc atgcctcgcg gacgccaccg
    14881 tcgggcccac ccccgcggac cgctacgtgt cggcccacct ggcggccctc cgtgcggccg
    14941 ccgggatcct cgcggcgcgt ccgcggccga tggacggccg caggcggcgc ctgcgcagcg
    15001 cctgggagct gctgccggag gccgagccca agctcgcgga ctgggcggcc tacttcgcgg
    15061 tgagcgcgac caagcgtgcg gcggccgagg ccggcatggt ccgcgccgtc acgcagaacg
    15121 acgcggaaga gatcatagcg gaggcggaca ggttcgtcgg cgaggtcgag tcgatcctcg
    15181 gtctgccggg ccgccccacc ctgcccatgg ccggctgacc accgatcccg gcacggcgcg
    15241 gatcggcagg gtcgccacca tgccgagcgc cgtcgccaga cccggccggc tcgctgcggc
    15301 caggcgtgcc gcaggggagg acgagcggcg cggccgcgtc cgatgaccgg ccgccgcgcg
    15361 gtgtctcggg tccgctcctg ccgtgggcgg gccgcgggtg ctcagacggg gtcgcgctcc
    15421 agggggcagc tcatgcaccg gggcccgccg cgtccgcggc cgagctcgct gccgcggatc
    15481 gggatgacct cgatgccgtg cctgcgcagg tggttgttgg tcgtggtgtt gcgttcgtag
    15541 gcgacgacca cacccggctc cagcgccagc acgttgcagc cgtcgtccca ctgctcgcgc
    15601 tcggccgcgt gcacgtcctg cgtcggcgtg aggaccttga tgtcgtccag gccgagggcc
    15661 cgcgcgatcg ccttgtgcat gtcctccggc gggtggtcgg tgaccttcag ctccttgtcg
    15721 gtgtcgcccg gctccaccgt gtacgaggga agcatgccga gcccggcgta cttggtgaac
    15781 acgcccacgt cgacgttggt catcacggtg tcgaggtgca tgaacgcacg ggtcttgggc
    15841 aggtcgagcg ccacgatgcg ggtcgccgac cccgcccgga acaggttggt ggccagcatc
    15901 tcgaccgcct gcggctgggt gcgctcgctc accccgacga gcacgacgcc gccgccgagc
    15961 accaggacgt cgccgccctc gatggtggcc ggggccatgc gcacgccctc gtaccagacg
    16021 ttgaaccccc cgtcgtccgg gttgccgtag cccgcggcga acagcggatg ccagcgatag
    16081 acggcctcgt agttgacggt ctcccgcctg cgcgccttct tgcgcatcgc gttgatcgac
    16141 accccgtcgt acacccagca ggaggtgtcg cgggcgaaca ggtggttggg cagcggcggg
    16201 aggacgaagt cgtccatcgc cagggtgtgg aaggtgatgg agcccgggtc gcagcccagc
    16261 tccatgatct cgcgcttggt gatcccgccg gtcagcagcg gtgcgagcgc gtcggcgtcg
    16321 agtgagtcga gcgtgttgcg gatcgcgtcg gcggtcagcg ggccgaacca gtgctcgtcg
    16381 acgctgccgt cgaggatgtg cttgcgcgcg tcggggatct cgatcacctc gcgcaggagg
    16441 tcgccgaggt ggtgcaccgt gacgccgcgc ccggcgagca cgtcgcacca ctcgcggtgc
    16501 tcctccagcg cgcggtgcac ccagagcacg tcgtcgaaca gcaggccgtc cttgttgccc
    16561 ggggtgagcc gcttgagcgc gagttcgggt atgtcgacca ggacgcggcg aagcctgccc
    16621 acctcggagc ccacgtaaaa cgtcatgtcc tgcactatcc ccgcgtggcg ggaatcactc
    16681 gtaccggcgg ctccccggtg cggtggcgcc gtctgagcca cacgcggcag ggcgtgattc
    16741 gtgcaccgtg acggggagcc gcgtacgagc cgggcaggag gtcagaagga ctcgacggcg
    16801 cggcgggcct ccgcgtcgag cacaccccag tggatgaact cctcggtcag ctcgaccggc
    16861 gacttgtcgt agatgaccgc gagcgagcgc aggtcctcct gccggatgga cagcaccttg
    16921 ccgttgtagt cgccacgctg gctctggatc gtcgcggcgt aacgcgccag cgggccggcc
    16981 ttgtccttcg gcagctgcga caggcgctcc aggtcgatga ccagcttggg cgcgggcgcg
    17041 agcggactgg gggcggctcc gccgggaaga agctccgaca ccggcactcc gtagaaatcc
    17101 gcgagctcgg cgagcttctg cacggttacc gcgcggtcgc cccgctcata ggagcccacg
    17161 acgacggcct tccaccgtcc gcgggacttc tcttccacac cgtgcaggga caacccctgc
    17221 tgggtccgga tggcgcgcag gcgcgcgccc agcgacttgg cgtagtcaga cggcatcgtg
    17281 tggcccccgg ctttctatgt ctcttctcac ttgattgtgc gcccttgtcc taagcgttcc
    17341 gaacaccggg gctggtgcct gtgaccggca ccttcggtga ccgctgcgtc gggttttacc
    17401 caggaaggtc gcgtgttgtg gttacggaca gtgacggtaa agccgacact cccaaaggtc
    17461 aagctgattg gaaaaaagag cgtcaaacag tgctctcccc gaaatccccg acacccggcg
    17521 cgatgcggct tccgatcccc gatacgtaac cggcacgtct cccgtcgcgt cctccccacg
    17581 ccgccggcga gcggccccgg gggtgtatca cccctggcgg gaggggggtt cgcagacggc
    17641 cctgatactc taagcagacc gaacaccctt taagacccgt cccgtgaggc gggaaaggtg
    17701 gtgacttttt catgtctgat gcccgaaatc cggcccgcgc cgtcctggag gggcccgaca
    17761 tccaccgggc gctcacccgg atcgcacacg agatcctcga acggaccagg ggcgcggaga
    17821 gcgtcgtcct gatcggcatc cccacccgcg gcgccaccct cgcgcagcgc atcgccgggc
    17881 gcatcgcgca gttcgagggg atcaaggttc ccgtcggcgc catcgacgtc acgatgtacc
    17941 gcgacgacct gcgcctgcgg cccgcgcgcc cgctcggccg caccgaactg cccccggacg
    18001 gcgtggacgg caggaccgtc gtcctggtgg acgacgtcct ctactccggc cgcaccgtgc
    18061 gcgccgcgct cgacgcgctg aacgacgtgg gcaggcccag ggcagtccag ctcgccacgc
    18121 tcgtcgaccg cggccaccgg gagctgccga tccgcgccga ctacgtcggc aagaacctgc
    18181 cgacctccaa gagcgagaag gtcaaggtct tcctggagga gacggacggg cgcgacgcgg
    18241 tcgtgctcat caaggaggac gaccgatgaa gcggcacctg atctcgaccg gcgacctcac
    18301 ccgcgacgac gccctcctca tcctcgacac ggccgaggaa ctggcccagg tctcgcagcg
    18361 gtccatcaag aagctgccga cgctgcgcgg ccgcacggtg gtgaacctct tcttcgagga
    18421 ctccacccgg acccgcatct cgttcgaggc cgcggccaag cgcctgtcgg ccgatgtgat
    18481 caatttctcg gccaagggat cgagcgtgtc caagggcgag tcgctgaagg acaccgcgct
    18541 caccctggag gccatgggcg ccgacgccgt ggtcatccgg cacagcgcct ccggcgcgcc
    18601 gcaccgcctg gccaactggg tgcgcggcag cgtggtcaac gccggcgacg gcacccacga
    18661 gcaccccacc caggcgctgc tcgacgcctt cagcatccgc cgccggctgg gccggctgga
    18721 gggcctgaag atcgccatcg tgggcgacgt gctgcacagc cgggtcgccc ggtccaacgt
    18781 gctgctgctg cacacgctcg gcgcggaggt gacgctggtc gcgcccccga ccctgctgcc
    18841 ggtcgcggtc gggacgtggc cctgccaggt ctcctacgac ctcgacgccg tgctgcccaa
    18901 gtcggacgtc gtgatgatgc tgcgggtcca gctcgaacgc atgaacgcgg cctacttccc
    18961 ctcggcgcgg gagtacagcc gccgctacgg cctcgaccgc gaccgcttcg cccgcctgca
    19021 cgacgacgcc gtcgtcatgc accccggccc gatgaaccgc ggaatggaga tctccgcgga
    19081 ggtcgccgac tcgccgcgct cgacgatcgt cgagcaggtc accaacggcg tgaccgtccg
    19141 gatggccgtt ctctacctgc tgctcggcgg atccgagccc gcgatcggag gcgccgaatg
    19201 agcacccacg accttcacga ggggacggct gtgagcacca tcctcatcag gggcgcccgg
    19261 atcctgggcg gcgccccgag cgacatcctg ctgcgcgacg gcgtcgtggc ggagaccggc
    19321 gacctcgcgg gcgcgagggc cgaccagacg gtcgacgccg acgggctggt cgccctgccc
    19381 ggcctggtgg acctgcacac ccacctgcgc gagcccggcc gggaggacgc cgagacggtc
    19441 gagaccggga cccaggccgc ggcgcgcggc gggtacaccg ccgtccacgc gatggccaac
    19501 acctcccccg tggccgacac cgccggcgtg gtggagcagg tctggcggct cggccaggag
    19561 cacggccact gcgacgtgca gcccgtgggc gcggtgacct ccggcctcca gggccgccag
    19621 ctcgccgagc tcggcgcgat ggccgactcc gcggcccgcg tgcgggtctt ctccgacgac
    19681 ggcaagtgcg tgtccgacgc cgtgctgatg cgccgggcgc tggagtacgt caaggcgttc
    19741 gacggcgtcg tcgcccagca cgcccaggag ccgaggctga ccgagggcgc ccagctcaac
    19801 gagggcgagg tgtcggccag gctcggcctg accggctggc cggcggtcgc cgaggaggcg
    19861 atcatcgcgc gtgactgcct gctcgccgcg cacgtcggct cccggctgca cgtctgccac
    19921 gtctccaccg cgggctcggt cgagatcatc cgctgggcca agtcgaaggg ctgggacgtg
    19981 accgccgagg tcaccccgca ccacctcctg ctgaccgact cctgcgcgga gcgctcgccg
    20041 ctcggcccgt acaacccgat ctacaaggtg aacccgccgc tgcgcaccgc cgaggacgtg
    20101 cgggcgctgc gcgaggcgct ggccgacggc acgatcgact gcgtggccac cgaccacgcg
    20161 ccccacccgg tcgaggacaa ggagaccgag tgggccgcgg cggccatggg catgatcggc
    20221 ctggagaccg ccctgtccgt ggtccaggag gccatggtcg agaccggcct gctcgactgg
    20281 gccggcgtcg ccgaccgcat gtcggcgcgg cccgcgagga tcggccgcct gaccgggcac
    20341 ggccgcccga tcgagcccgg cgcccccggc aacgtcaccc tgtacgaccc gtcgggccgg
    20401 cagcccgtgg accccgccgc gatggtgtcg aaaagccgca acacccccta cgaggggctg
    20461 accctgcccg gccgcgtcgt cgcgacgttc ctgcgcggcc gccccaccgt tctcgaaggg
    20521 aagctcgtat gacagccctg ctcgtgctcg aggacggacg cgtcttcgag ggaacgccgt
    20581 acggcgccgt gggcgagacg ttcggcgaga tggtcttcaa caccggcatg accggctacc
    20641 aggagacgct caccgacccc tcctaccacc ggcagatcgt ggcgatgacc gccccgcaca
    20701 tcggcaacac cggcgtcaac gacgaggacc ccgagtcccg cagggtctgg gtcgccggct
    20761 acgtggtgcg ggagccgtcg cggatcccct cgaactggcg ctcccgcagg acgctcgacg
    20821 aatatctgcg cgaccagggc gtcgtcggga tcgcgatgcc cggcacccgt gccctcaccc
    20881 gccacctgcg cgagcgcggc gcgatgcgcg cgggcgtctt cagcgagggc ggcgacgtcg
    20941 ccgagctcgt cgagcgggtg cggcgcgcgc ccggcatgga gggcgccgac ctggcccgcg
    21001 aggtcagcac gcccgagccg tacgtcgtgc cggccgtcgg ccgcaagcgc ttcaccgtcg
    21061 ccgcggtc
//
