LOCUS       NZ_JABBXA010000001     45829 bp    DNA     linear   CON 07-NOV-2024
DEFINITION  Microbispora sp. H13382 NODE_1, whole genome shotgun sequence.
ACCESSION   NZ_JABBXA010000001
VERSION     NZ_JABBXA010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora sp. H13382
  ORGANISM  Microbispora sp. H13382
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 845565)
  AUTHORS   Liu,C.
  TITLE     Selective isolation, identification and anti-microbial activity
            study of Microbispora
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 845565)
  AUTHORS   Liu,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-APR-2020) Microbiological Resources Collection Center,
            Sichuan Industrial Institute of Antibiotics, 168 Huaguan Road,
            Chengdu, Sichuan 610052, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014161445.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 07:22:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,982
            CDSs (total)                      :: 7,906
            Genes (coding)                    :: 7,786
            CDSs (with protein)               :: 7,786
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 21 of 121
            Pseudo Genes (incomplete)         :: 104 of 121
            Pseudo Genes (internal stop)      :: 8 of 121
            Pseudo Genes (multiple problems)  :: 11 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:45:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 77450
            Orig. end                         :: 123279
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABBXA010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..45829
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T1PKS"
                     /region_number="2"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..45829
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..45829
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:25829](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..25829
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            complement(138..851)
                     /locus_tag="HHX41_RS00300"
     CDS             complement(138..851)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017541273.1"
                     /locus_tag="HHX41_RS00300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="isochorismatase family protein"
                     /protein_id="WP_169979404.1"
                     /transl_table=11
                     /translation="MAGIPQIAPYSMPEAGELPGNTASWTVDSRRAVLLLHDMQNFFLE
                     PFPAGRPPVVDLVGNATALRNRCARLGIPVAYTGQPGDMTEEQRGLLREFWGPGMTAEP
                     SHRDIVAAVAPAPGDWLFTKWRYSAFHRTTLLSRMRESGRDQLILAGVYAHVGILMTAV
                     DAFTNDIQPFLVADAIADFTAADHRMTLDYAARRCGVTVTTEQVLADLSAAPDLSPTPG
                     LAPVPGLSSSSEGQR"
     misc_feature    872..881
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.52"
                     /tool="antismash"
     gene            complement(890..1651)
                     /locus_tag="HHX41_RS00305"
     CDS             complement(890..1651)
                     /EC_number="1.3.1.28"
                     /GO_function="GO:0008667 -
                     2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (1-161). E-value: 3.2e-16. Score:
                     51.7. Matches aSDomain:
                     nrpspksdomains_HHX41_RS00305_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EntA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017589682.1"
                     /locus_tag="HHX41_RS00305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase"
                     /protein_id="WP_169979402.1"
                     /sec_met_domain="adh_short (E-value: 4.2e-36, bitscore:
                     120.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.3e-06, bitscore:
                     22.4, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="EntA (E-value: 1.2e-105, bitscore: 348.3,
                     seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 3.9e-30, bitscore:
                     101.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVALVTGAAGGIGAEVARVLAEDGVPVAAVDRDAGALRTVVGKLV
                     ADGLEAAAFTADVTSAPQVEAVVDEVERRLGPIDRLVNAAGVLRVGEARTLSDDDWAAT
                     FAVNVTGVFHVSRAVVNRMVPRRAGAVVTVASNAAHTARIGMSAYGASKAAVTMFTKNL
                     GLEVARYGIRCNVVAPGSTDTPMLTSLWHDDDGHRASIEGAPDLYRTGIPLRKIARPAD
                     IAEAVAFLLSERAGHITLQHLTVDGGATLGA"
     aSDomain        complement(1169..1648)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHX41_RS00305_PKS_KR.1"
                     /evalue="3.20E-16"
                     /label="HHX41_RS00305_PKS_KR.1"
                     /locus_tag="HHX41_RS00305"
                     /protein_end="161"
                     /protein_start="1"
                     /score="51.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VALVTGAAGGIGAEVARVLAEDGVPVAAVDRDAGALRTVVGKLVA
                     DGLEAAAFTADVTSAPQVEAVVDEVERRLGPIDRLVNAAGVLRVGEARTLSDDDWAATF
                     AVNVTGVFHVSRAVVNRMVPRRAGAVVTVASNAAHTARIGMSAYGASKAAVTMFTK"
     CDS_motif       complement(1580..1642)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHX41_RS00305_0001"
                     /evalue="3.50E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="HHX41_RS00305"
                     /protein_end="24"
                     /protein_start="3"
                     /score="19.7"
                     /tool="antismash"
                     /translation="LVTGAAGGIGAEVARVLAEDG"
     misc_feature    1713..1724
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     misc_feature    complement(1784..1795)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.01"
                     /tool="antismash"
     misc_feature    complement(1955..1969)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.95"
                     /tool="antismash"
     misc_feature    complement(1960..1973)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.32"
                     /tool="antismash"
     misc_feature    complement(1961..1976)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.8"
                     /tool="antismash"
     gene            1969..3009
                     /locus_tag="HHX41_RS00310"
     CDS             1969..3009
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF005112.0"
                     /locus_tag="HHX41_RS00310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prephenate dehydrogenase"
                     /protein_id="WP_396793808.1"
                     /transl_table=11
                     /translation="MSSHGFLPGRDEGWQEAVPPGHLAAAALSGRCHANARDCRCGDPY
                     SHQGRGMMTSSSIRRVTIIGCGLIGASAALALRKAGVEVALSDRDPHAVAVAERMGAGV
                     ALTPGAPAADVVVVATPPSTVAAVLRDAQARGLGAVYTDVASTKARVVAEAERAGCDLT
                     AYVPGHPMAGAEASGPLAARADLFAGRPWTLCPLPTTPLRPVRVVAELVAACGAEHRLL
                     APDVHDLAVAASSHAPHLVSAALAARFAGADETTLSLVGPGLRDVTRVAGGAPGLWCDI
                     LRQNAEPVAAVLEAVARDLAAAAAALRDPEGGQLLADLLTKGNDGRARIVGGGAEHTAP
                     AGALAA"
     misc_feature    complement(3402..3416)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.23"
                     /tool="antismash"
     gene            3410..4591
                     /locus_tag="HHX41_RS00315"
     CDS             3410..4591
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893406.1"
                     /locus_tag="HHX41_RS00315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_169979398.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.1e-09, bitscore:
                     33.6, seeds: 790, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTTGVPTREELVRRASELLPLLRGHADWAEENRRIHDESIEALA
                     DAGVFKMRVPARYGGYECDTRTLLEVAAELGRADGSTAWTASVYWIPTWMTCLFPDEVQ
                     DEVFSTPDVRVCGTLSPTAMAAPVDGGVVVNGKWGFVSGAWHSHWQEIVAIQVGPEGEP
                     MPIMALVPMSDLQIVDDWHTSGLRGTGSVTTVAQDVFIPAERVLPLPAVLMGQYASKLN
                     AASPIYRTPLLPVASASSVGTVIGLARAAREAFFERLPNRKITYTHYESQSEAPLTHLQ
                     VAEASLKIDEAEFHAQRLTGLVDGKGVTGEQWTLEERARARADMGAVCRLGKEAADVLA
                     MASGGSSIYTQVPIQRIARDITAVNLHALMHPNTNTELYGRVLCGQEPGTFYI"
     gene            complement(4764..5039)
                     /locus_tag="HHX41_RS00320"
     CDS             complement(4764..5039)
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (16-81). E-value: 9.5e-20.
                     Score: 62.7. Matches aSDomain:
                     nrpspksdomains_HHX41_RS00320_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.5"
                     /locus_tag="HHX41_RS00320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl carrier protein"
                     /protein_id="WP_169979396.1"
                     /sec_met_domain="PP-binding (E-value: 7.9e-17, bitscore:
                     57.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGNHPGELVLPVIEAKVAEIWKQVLDVPDGSEDATFFDLEGESI
                     AAVRLVSRIEEELGVSVDVGDVFEEDPNLDALVRMVAGKAAVSPAA"
     aSDomain        complement(4797..4991)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHX41_RS00320_PP-binding.1"
                     /evalue="9.50E-20"
                     /label="HHX41_RS00320_PP-binding.1"
                     /locus_tag="HHX41_RS00320"
                     /protein_end="81"
                     /protein_start="16"
                     /score="62.7"
                     /tool="antismash"
                     /translation="KVAEIWKQVLDVPDGSEDATFFDLEGESIAAVRLVSRIEEELGVS
                     VDVGDVFEEDPNLDALVRMV"
     gene            complement(5151..8210)
                     /locus_tag="HHX41_RS00325"
     CDS             complement(5151..8210)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890454.1"
                     /locus_tag="HHX41_RS00325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_310741683.1"
                     /transl_table=11
                     /translation="MRQHTVLAVLLLEANRPVAVGRLMEAIYGDDPPATSRAQVQICIS
                     ALRRLFGAHGHDQMIVTRSQGYALRTDSEQIDAHRFESLVLKARQARDNRDVDEAVRHY
                     REALSLWRGPALEGIESRMVQAAASWLDEERLAANEDCVQLELDLGRHHELVTELRRLV
                     EEHPLRERLLGQFMTALYRSSRQAEALQVYRDARRMMIDELGIEPNERLQQLEHGILTA
                     DESLDAPPERDSARISVAEPAAPPPVPGMLPSGIADFIGRHGHLDEIRRRLTQVSDGMA
                     RFAVPIIAIAGRAGIGKTTIAVHAAHSVADHYPDGQLFAHMHGGVSRPVSPMQVLERFL
                     RALGVPGTALPDGLEERAETYRTLLADRRMLIVLDDVGSESQVLPLLPGNPASAVIVTS
                     RSRLVGLAGATHIDVDLFDSAQSVDLLAQVAGGGRVASEQSSAEALADLCGHLPLALRI
                     AGARLAARPHWTVEQLVDRLRDETRRLDELMHGEMGIRASLSLTYDNISEEARRLLRRL
                     AILDSHVFSVWTGAALLDRSFIEAQDLLDNLADAHLVEVTVGRGTHTQYRFHDLVKVFA
                     RERLAAEEPVAERKAALSRVLGSLLSLTDAARSREFGSDVLARMESVIPRPLPEKLVEQ
                     LVAEPMAWFERERHLLVSGIRQAAQAGFVELCWRLAANAAMFFESRVYLDDWRETHELA
                     LEAARQAGDRRGQAEMLYTIGSLSFSEQRFDDARRELDAAVRLFEEVGDELRIALAIRS
                     IAVLERINGRFAEAVANYEKALQVFHTAGDHVSAAHTLHSLAQVRLDCDDLDSAKSLLS
                     EALTRSKAGGDRRVTAQVLHRMGQAHLQAGEFGLSAGAFEESLTVVRDIGDSIGEAFAL
                     HGLGVARLRQGRIAEAGETLREALRLATSSRHRLAEARVMSGLGEVAVANGENDQAAVH
                     LRRAASLFRGMQMPLLEAQTLIMLSDALYATGDYDEADDAMTRTLDLADRIDPRAGRQV
                     RDRLSRTRRARPDARGGLRISDGLGPVVRT"
     misc_feature    8296..8314
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.72"
                     /tool="antismash"
     misc_feature    complement(8387..8401)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.48"
                     /tool="antismash"
     misc_feature    8486..8501
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.6"
                     /tool="antismash"
     misc_feature    8608..8622
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.97"
                     /tool="antismash"
     gene            complement(8701..8910)
                     /locus_tag="HHX41_RS00330"
     CDS             complement(8701..8910)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX41_RS00330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_182904359.1"
                     /transl_table=11
                     /translation="MAGSSSIVKRFAVSIFIALTAAASAGAMVSVAAASHAHARTVVHR
                     SVQPHSPAGIPSPSPTNTHVNPWD"
     gene            9299..9637
                     /locus_tag="HHX41_RS00335"
     CDS             9299..9637
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012785.5"
                     /locus_tag="HHX41_RS00335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxyisourate hydrolase"
                     /protein_id="WP_169979391.1"
                     /transl_table=11
                     /translation="MGIALQALDGLYGRPAAGVRVRLERSDNGLWCAEVKAETDHEGRV
                     GEWRGRRFDRGLHRIVFESDSYFVGLGLTAAYPEVSITFRMHDETDSYQLQVLLSPYSY
                     SAYFGSLT"
     gene            9648..11444
                     /locus_tag="HHX41_RS00340"
     CDS             9648..11444
                     /EC_number="2.3.3.13"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547682.1"
                     /locus_tag="HHX41_RS00340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-isopropylmalate synthase"
                     /protein_id="WP_310741684.1"
                     /sec_met_domain="HMGL-like (E-value: 4.3e-75, bitscore:
                     248.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLGRYSGSSRVPLEGRAWPDATIGSAPRWLSTDLRDGNQSLAEP
                     MSPARKLIMFDLLVDVGYKEIEVGFPAASKDDHDFVRMLVERDLIPDDVRISVLTQARD
                     ELIERTVASLEGAPRATVHLYAATSPLFRGLVFGMSRDECKDLAVQGTRLVMKYAERTL
                     DGCDLGYQFSPEHFADTEPDFALEVCEAVMDVWQPEAGRETVLNFPTTVERATPNVFAD
                     RIEWMHRNLSRREHLCLSVHPHNDRGTGVATAELAVMAGADRVEGCLFGNGERAGNVCL
                     VTLGLNLSTQGVDPGVDFSDLDRVRRTVEHCTGVPVHPRHPYGGDLVYTAFSGSHQDAI
                     KKGLDAVEREAVRTGDDAAHLPWQVPYLPLDPQDVGRTYEAVVRINSQSGKGGLAYVMS
                     AWHGLTLPRDLQADFAMRMQALTDAEGGEVAPERVLEVFVREYVVDSALPVPPSVEARG
                     TVTLHIDAGWFRTGPARTDTVQAVRAELARRGLRVRVVHHTRPAAGAGAAGRDDAAVYA
                     EYRTGGACYWGAGIERDVERAALVAVCSAVARAARDRAPATGDGQGDGRSDGRGGGRGA
                     TEGNGRHGRQGAGRSRRVTAGR"
     gene            11449..14316
                     /locus_tag="HHX41_RS00345"
     CDS             11449..14316
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547681.1"
                     /locus_tag="HHX41_RS00345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AAA family ATPase"
                     /protein_id="WP_310741685.1"
                     /transl_table=11
                     /translation="MKGGDTAMAMVEREQELVLLEALLASAVMGRGRVALVGGAVATGK
                     STLLHTFAEQAIELGALAVTATGSPLERDVPLGVLRQLVEDAPLVPQERERALSLLEEG
                     ARAVAAGADERRPVDAQLVHALCGVLLDLSERCPLVLVVDDVHHADRESLLCLAYLARR
                     VRLAQIVAIFGHADQAWHTDSYFQTELLRQPHCRRVRLTRLSRAGVAAMLAARLGDEAA
                     ERLADEMYAHSGGNPLLVTALADDYEESARTAPEPPAGVVVGEQYGQAVLSCLSRGEAR
                     VARAARGLAVLGEPRSLDLLLGVPAAEVNKDLHSLGAAGLTALGTFRHEAARQAVLGAM
                     DAGERAELHRRAAELSYGVGASPAVVARHLLEAGRVDAPWGIEILEEAARSALRAGQVD
                     SAVGYLRLAWRACADDTQRAKIMTMLVRAEWRINPAAPAGRLAELAEAVHRGSLRGGDA
                     VVLARALLWHGRVDDARDVLEQVLESGGTADQETRAELVVARLCLRAAHPPFLTALGHM
                     TKEEGPGGIVSVSVSRRLESALALAEVLTRGPREEYVDAVERILEDSRLDEMSLDTVEN
                     SLLTLTYAGRAERAAPLCDMFAAEASARQAPSRRARLAAIRAEIAIRQGDMPAAERHAR
                     AALQIIPMSGWGVAVGGPLGSLIFALTTMGRYDEVREHLDVPVPEVMFQTRYGLHYLHA
                     RGRHSLATGYPALALGDFRRCGDLMTEWNLDTPGLIPWRADAAEACLRLGRVEEARELV
                     RDQLDGCVPDDPRGRGVALRLLAATLDPGDRPALLRQATGCLQAAGDRYELARALADLV
                     ETYDALGEYRRARTIATWAQAVAAECGVEPPASSLSPAHQQSHGAPRSGSHGGSSTGSG
                     GGPERGATATAARPSAVPLGELSDAERRVASLAAAGCTNREIAAKLFVTVSTVEQHLTR
                     TYRKLGITRRSDLPLVLEFGEQAGV"
     gene            14444..14695
                     /locus_tag="HHX41_RS00350"
     CDS             14444..14695
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004658 - propionyl-CoA carboxylase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017595030.1"
                     /locus_tag="HHX41_RS00350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA carboxylase epsilon subunit"
                     /protein_id="WP_182904361.1"
                     /transl_table=11
                     /translation="MEDSTDLIVVRGDPTPEELAAVVAVVAAVAARAGSAAAAPEPPAA
                     PVSPWASAWAAFAWLAPGPRPVARGAWSSPNVRWHWIA"
     misc_feature    complement(14725..14739)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.07"
                     /tool="antismash"
     misc_feature    14726..14739
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.3"
                     /tool="antismash"
     gene            14882..15868
                     /locus_tag="HHX41_RS00355"
     CDS             14882..15868
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893434.1"
                     /locus_tag="HHX41_RS00355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1702 family protein"
                     /protein_id="WP_182904362.1"
                     /transl_table=11
                     /translation="MSTLSGSLRRLVLAPSLLDVTFAERGFPGSPSEVTRRLETIPQAV
                     VCGFEWGIDARDQWEVERRLNMIEPELRGFAYEGATMAFTVLDAMGGGRGRRTRDLLLG
                     PGRPHIFLTYIGIGFAMARLPRVLWRKVMPDLGGSPYYPTMSWLAVDGYGFDRAYFDTR
                     RWVDEQRIPSPYPWEGSPDYFLRAVDQGIGRALWFIHGARVGDVATAVRRFASHRQADL
                     WSGVGLAATFAGGCDADTLAVLRREAGEHGPEVAQGVVFAAKARSYAGFVPAHTEVATA
                     ALAGLSVRDAVALADDSEVAPDPSASVPAYELWRGRVREHFAARLVA"
     misc_feature    15894..15907
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.49"
                     /tool="antismash"
     gene            16064..17023
                     /locus_tag="HHX41_RS00360"
     CDS             16064..17023
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893433.1"
                     /locus_tag="HHX41_RS00360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1702 family protein"
                     /protein_id="WP_259400540.1"
                     /transl_table=11
                     /translation="MRRRIMTPDISETKLATRGFHVKSPEARDLLETVGETFLKGYGYA
                     MEACTVAEAEERLEQVPTRFRGFAYEGAGMAFAILDGMPFGGGRVEEFLAGRGGRHNYM
                     IYVGVGWAMARLPRFLWPKAESLDPLLRWLALDGYGFHQAYFRTDQYVHGQYRDPAFPW
                     PADATRPYANRAIDQGIGRAIWFVAGTDAERCADLIDRFDPSRRADMYAGAGLAATYAG
                     GAAEEELLTLRERAGEHRPLLAQGAAFAAEARVRAGLVVPHTRLAAEILCGLPEDRAAQ
                     VTQLVRPPQPLRDGDPPAYELWRQCIANEFVSLGGVTQ"
     gene            17020..18987
                     /locus_tag="HHX41_RS00365"
     CDS             17020..18987
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893432.1"
                     /locus_tag="HHX41_RS00365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CRTAC1 family protein"
                     /protein_id="WP_182904363.1"
                     /transl_table=11
                     /translation="MTATLGWLRRQTAGIVALVLIATAFLIARLPSYSAAQTAETASKY
                     SFTPLSIALPSGYDQQSIRKVNKDYTHIDAWISSVGAAIAMNDLDGDGLSNDLCLVDTR
                     IDQVVITPTPGAKSERYAPFALNPAPLPVNDHMAPMGCVPGDYNEDGRLDLLVYMWGRT
                     PILYLAKTGAKGLSATTYKPTELVPGVNVTNGEYTGPQWNTNAATVADFDGDGHDDIFI
                     GNYFADGPVLDPTVSGGVHMNHSMSNGHNGGENYFFRWTGAKSGDKPAATYQKLDDVLP
                     EEVSKGWELGASANDLDGDLLPELYLANDFGPDRMLYNRSTPGHFKFSLVEGVRSPFIP
                     KSKSVGHDSFKGMGVDFGDLNHDGIYDMFVSNITTSWGIEESNFQFVADVKNQSELREK
                     FREGVAPYRDESAPAQTAWSGWGWDVKIEDFNNSGEPAIAQATGFIKGQTDRWPQLQEL
                     ATANDQMLQNPTWWPNARAGDDIAGNQTLHFFAKGPEGRYIDLAPQLGLNVPVPTRGIA
                     TGDADGDGRLDFAVARQWDAPIFYHNQSPAQGAFLGLRLTRDEKPADGALPAAGSPVTG
                     AQVCVMTPDGRKFISRVDGSSGHSGRRTTDVHIGLGQNVTGPVKVLLQWRDRTGQVREQ
                     DLQLTPGWHSLKLGRQAKEK"
     gene            18994..20004
                     /locus_tag="HHX41_RS00370"
     CDS             18994..20004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893431.1"
                     /locus_tag="HHX41_RS00370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="enediyne biosynthesis protein"
                     /protein_id="WP_169979381.1"
                     /transl_table=11
                     /translation="MAENTPVAGPRHDPKVVIALRNFAISISVFNIVGYTILGFEQPWL
                     WPFIALATGYTTEIVLERIGSRAEGRPPRYKGNGLRGLIEFLYPAHITSLAMNMLTYVN
                     DQVLVLVFGVVVAVGAKWVLRAPVKGRLRHYMNPSNFGIAVILLLFPWASIAPPYHFTE
                     NVDTWIDWLVPGIIIVGGTMLNGKLTGRMPLIAGWVGAFALQAILRGVFFGTSIPAALA
                     MMTGVAFILFTNYMITDPGTTPSKPGSQIAFGAGVALLYGLLTAVHISYALFFATAGVC
                     AIRGGFFWALHFVNKARQQAQAPAQAQAPSIPSQTPAPVIVTGPVSVNGKEAASV"
     gene            20001..25829
                     /locus_tag="HHX41_RS00375"
     CDS             20001..25829
                     /EC_number="6.4.-.-"
                     /NRPS_PKS="Domain: PKS_KS(Enediyne-KS) (5-463). E-value:
                     2.6e-100. Score: 328.2. Matches aSDomain:
                     nrpspksdomains_HHX41_RS00375_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (615-845). E-value: 4.4e-55.
                     Score: 179.1. Matches aSDomain:
                     nrpspksdomains_HHX41_RS00375_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1205-1387). E-value: 2.1e-34.
                     Score: 111.0. Matches aSDomain:
                     nrpspksdomains_HHX41_RS00375_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_DH (1463-1600). E-value: 5.9e-12.
                     Score: 38.2. Matches aSDomain:
                     nrpspksdomains_HHX41_RS00375_PKS_DH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     ene_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657665.1"
                     /locus_tag="HHX41_RS00375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_182904364.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.3e-57, bitscore:
                     190.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 1e-267, bitscore: 883.5,
                     seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 5.6e-54, bitscore: 179.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTRIAIVGMACRYPDAASPRELWENALAGRRAFRRLPDERMRL
                     EDYWDPDPSVPDRFYARTAAVIEGYEFDRVGYRIAGSTYRSTDLTHWLALDMAGRALAD
                     AGFPEGEGLPRERTGVVVGNTLTGEFTRANILRLRWPYVRRTVAATLKDQGWDDERLAA
                     FLADLEATYKSPFPEVDEDTLAGGLSNTIAGRICNHFDLNGGGYTVDGACSSSLLSVTT
                     ACKALLDGDLDVAVAGGVDLSIDPFEIIGFAKTGALAKGEMRLYDKHSNGFWPGEGCGM
                     VVLMRESDAVEAGRRIYAVIAGWGVSSDGRGGMTRPEVSGYRLALSRAYDRAGFGIETV
                     GLFEGHGTGTAVGDATELTALSEARTDAAAATAPAAVTSIKGMIGHAKAAAGVAGLIKT
                     AMAVHEQVLPPAIGCVEPHQILAKQDAPLRALRKAEPWPEDVPVRAGVTAMGFGGINTH
                     VVLEKSGPRRRVLPARTRSLASSLQDAELLLADAASPQALRERVATLADFVTRLSYAQL
                     ADLAVTLQRELRDQPYRAAVVVSSPEDAERQLRRVLTALDGGETSLFASDGRAFLGHAD
                     GPCRIGFLFPGQGSGRGTSGGALRRRFPEVEEIYARAALPSSGDMVATAVAQPRIVTGS
                     MAGLRALSLLGLEADVAVGHSLGELSALQWAGAMDEDTLLGLAAARGRAMTEHSSSGTM
                     AGIRATPQTVTDLIAGLPVVIAGYNGPSQTVVAGPADAVEEAGRRASDAGLNWTPLAVS
                     HAFHSPLVAPAAEAFGAYLAGQEFGPVGRRIVSTVTGEDLPPVADLRELLRRQITEPVR
                     FTQAVERAAKDVALFVEVGPGRVLTGLAAAATEVPAVALDTDDESLAGLLRVAGAAYVT
                     GVPVLLEDLFHGRLVRPLEIGAEFSFFASPAEAAPRVTVAATRARAAGEAAPPAATAAP
                     VVSADAAAEAGSSIDLLRRLAAERAELPLEMVSEDSRPLDELHLSSVTVMHIIDQAVQR
                     LGVPAAQAPTNLATASLRELAEALDRLTREPQGRAAAPAAVVAGAADWARPFAVDLDEV
                     PLPARTGPGDSGRWRLYAAGSSPIAEPLRRALEEGNVGSGVLVCLPPDCAEEHLEQALL
                     GAKAALAGPPGTRFVLVQHDRGAAGLAKTLHLEAPHLRTTVVHTPAVPEAVGRVVAEVA
                     ATTGFAEAYYDADGVRRVPTLRALPVRPATQVPPLGAEDVLLVTGGGKGITAECALAVA
                     TDSGAKLAVLGRSDPAGDAELAATLRRMAEAGVTVRYARADVTDPGQVRRGIAELEAEL
                     GPVTAVLHGAGRNEPAGLAGLDADAFGRTFAPKVGGLRNVLDVVDPGRLRLLVTFGSII
                     GRAGLHGEAHYATANEWLADLTREVADKHPGCRAICMEWSVWSDVGMGERLSVVEGLTR
                     KGIAAITPEQGVEIMRRLVADPASPVVVVISGRTEGIGTVRRDEPPLPLLRFVDRPLIR
                     YHGVELVTEVEVNAGTDLYLADHLLDGNLLFPAVFGMEAMAQVAYAATGRRETPAIEDA
                     RFLRPIVVPPAGSTTLRIAATVTGDDTVEAAIRSSDTGFEVDHFRARLRYTGEPAADGP
                     PGQVAEGLPPVTLDPAREMYGDLLFQGGRFHRLRRYHRAAARHVDADVAALADGDWFAR
                     YLPDTLLLGDPGTRDALMHGNQVCVPDATLLPVGIERVRPGGPALAEAGALRYCATERE
                     RDGDTYVYDIAVRTGDGTVVERWDGLTLQAVRKKDGGAGPWVAPLLGSYLERTLEDLTG
                     DRVAVVVEPGLPGEPDGAAGRGARAAVGLGRALGRPVEVRSGPGGEPEIGGEAGDGVAV
                     SAAHGAGVTLCVAGGGPLGCEIAEVTASGEGDGRWREALGPNAAVAERVAALTGEAPAV
                     AAARVLAGVRSLRRAGLPEDTPLAAGTVSGSWAVVDAGDARIATLVTSLRDVAGPVVIA
                     VLTEGRSRA"
     aSDomain        20016..21389
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHX41_RS00375_PKS_KS.1"
                     /domain_subtypes="Enediyne-KS"
                     /evalue="2.60E-100"
                     /label="HHX41_RS00375_PKS_KS.1"
                     /locus_tag="HHX41_RS00375"
                     /protein_end="463"
                     /protein_start="5"
                     /score="328.2"
                     /tool="antismash"
                     /translation="IAIVGMACRYPDAASPRELWENALAGRRAFRRLPDERMRLEDYWD
                     PDPSVPDRFYARTAAVIEGYEFDRVGYRIAGSTYRSTDLTHWLALDMAGRALADAGFPE
                     GEGLPRERTGVVVGNTLTGEFTRANILRLRWPYVRRTVAATLKDQGWDDERLAAFLADL
                     EATYKSPFPEVDEDTLAGGLSNTIAGRICNHFDLNGGGYTVDGACSSSLLSVTTACKAL
                     LDGDLDVAVAGGVDLSIDPFEIIGFAKTGALAKGEMRLYDKHSNGFWPGEGCGMVVLMR
                     ESDAVEAGRRIYAVIAGWGVSSDGRGGMTRPEVSGYRLALSRAYDRAGFGIETVGLFEG
                     HGTGTAVGDATELTALSEARTDAAAATAPAAVTSIKGMIGHAKAAAGVAGLIKTAMAVH
                     EQVLPPAIGCVEPHQILAKQDAPLRALRKAEPWPEDVPVRAGVTAMGFGGINTHVVLEK
                     "
     aSModule        20016..24800
                     /domains="nrpspksdomains_HHX41_RS00375_PKS_KS.1"
                     /domains="nrpspksdomains_HHX41_RS00375_PKS_AT.1"
                     /domains="nrpspksdomains_HHX41_RS00375_PKS_KR.1"
                     /domains="nrpspksdomains_HHX41_RS00375_PKS_DH.1"
                     /incomplete
                     /locus_tags="HHX41_RS00375"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       20616..20654
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHX41_RS00375_0001"
                     /evalue="9.40E-03"
                     /label="PKSI-KS_m3"
                     /locus_tag="HHX41_RS00375"
                     /protein_end="218"
                     /protein_start="205"
                     /score="8.9"
                     /tool="antismash"
                     /translation="GYTVDGACSSSLL"
     aSDomain        21846..22535
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHX41_RS00375_PKS_AT.1"
                     /evalue="4.40E-55"
                     /label="HHX41_RS00375_PKS_AT.1"
                     /locus_tag="HHX41_RS00375"
                     /protein_end="845"
                     /protein_start="615"
                     /score="179.1"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="PSSGDMVATAVAQPRIVTGSMAGLRALSLLGLEADVAVGHSLGEL
                     SALQWAGAMDEDTLLGLAAARGRAMTEHSSSGTMAGIRATPQTVTDLIAGLPVVIAGYN
                     GPSQTVVAGPADAVEEAGRRASDAGLNWTPLAVSHAFHSPLVAPAAEAFGAYLAGQEFG
                     PVGRRIVSTVTGEDLPPVADLRELLRRQITEPVRFTQAVERAAKDVALFVEVGPGRVLT
                     GLAAAATE"
     CDS_motif       21948..22055
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHX41_RS00375_0002"
                     /evalue="2.50E-08"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="HHX41_RS00375"
                     /protein_end="685"
                     /protein_start="649"
                     /score="25.9"
                     /tool="antismash"
                     /translation="DVAVGHSLGELSALQWAGAMDEDTLLGLAAARGRAM"
     CDS_motif       22146..22184
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHX41_RS00375_0003"
                     /evalue="7.20E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="HHX41_RS00375"
                     /protein_end="728"
                     /protein_start="715"
                     /score="9.8"
                     /tool="antismash"
                     /translation="AGYNGPSQTVVAG"
     aSDomain        23616..24161
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHX41_RS00375_PKS_KR.1"
                     /evalue="2.10E-34"
                     /label="HHX41_RS00375_PKS_KR.1"
                     /locus_tag="HHX41_RS00375"
                     /protein_end="1387"
                     /protein_start="1205"
                     /score="111.0"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="VLLVTGGGKGITAECALAVATDSGAKLAVLGRSDPAGDAELAATL
                     RRMAEAGVTVRYARADVTDPGQVRRGIAELEAELGPVTAVLHGAGRNEPAGLAGLDADA
                     FGRTFAPKVGGLRNVLDVVDPGRLRLLVTFGSIIGRAGLHGEAHYATANEWLADLTREV
                     ADKHPGCRAICMEWSVWSD"
     CDS_motif       23622..23714
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHX41_RS00375_0004"
                     /evalue="7.80E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="HHX41_RS00375"
                     /protein_end="1238"
                     /protein_start="1207"
                     /score="8.9"
                     /tool="antismash"
                     /translation="LVTGGGKGITAECALAVATDSGAKLAVLGRS"
     CDS_motif       23997..24086
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHX41_RS00375_0005"
                     /evalue="3.20E-05"
                     /label="PKSI-KR_m4"
                     /locus_tag="HHX41_RS00375"
                     /protein_end="1362"
                     /protein_start="1332"
                     /score="16.4"
                     /tool="antismash"
                     /translation="LRLLVTFGSIIGRAGLHGEAHYATANEWLA"
     CDS_motif       24279..24302
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHX41_RS00375_0006"
                     /evalue="9.10E+01"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="HHX41_RS00375"
                     /protein_end="1434"
                     /protein_start="1426"
                     /score="-2.7"
                     /tool="antismash"
                     /translation="PVVVVISG"
     aSDomain        24390..24800
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHX41_RS00375_PKS_DH.1"
                     /evalue="5.90E-12"
                     /label="HHX41_RS00375_PKS_DH.1"
                     /locus_tag="HHX41_RS00375"
                     /protein_end="1600"
                     /protein_start="1463"
                     /score="38.2"
                     /tool="antismash"
                     /translation="GVELVTEVEVNAGTDLYLADHLLDGNLLFPAVFGMEAMAQVAYAA
                     TGRRETPAIEDARFLRPIVVPPAGSTTLRIAATVTGDDTVEAAIRSSDTGFEVDHFRAR
                     LRYTGEPAADGPPGQVAEGLPPVTLDPAREMYG"
     CDS_motif       24438..24485
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHX41_RS00375_0007"
                     /evalue="1.70E-03"
                     /label="PKSI-DH_m2"
                     /locus_tag="HHX41_RS00375"
                     /protein_end="1495"
                     /protein_start="1479"
                     /score="11.1"
                     /tool="antismash"
                     /translation="YLADHLLDGNLLFPAV"
     gene            25826..26254
                     /locus_tag="HHX41_RS00380"
     CDS             25826..26254
                     /EC_number="3.1.2.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893429.1"
                     /locus_tag="HHX41_RS00380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thioesterase family protein"
                     /protein_id="WP_182904365.1"
                     /sec_met_domain="4HBT_2 (E-value: 2.4e-12, bitscore: 42.9,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDYYEYLHTVGFEETNIVGNVYYVNYLRWQGRCREMFLKERAPE
                     VLADLQDDLKLFTLKVDCEFFAEITAFDELSIRMRLVDLAQTQVEFSFDYVRLNPGEGE
                     TLVARGRQRVACMRGPNTRTAPARVPEPLVRALEPYAS"
     gene            26306..26821
                     /locus_tag="HHX41_RS00385"
     CDS             26306..26821
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893428.1"
                     /locus_tag="HHX41_RS00385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavin reductase family protein"
                     /protein_id="WP_169979818.1"
                     /transl_table=11
                     /translation="MDGQVNDAKALRRAFGAFATGVTVVTTGGSVPHAMTANSFASVSL
                     DPPLVLVCIDRAAVMHQCLSMTGFFGVSVLAAHQESEARHFANRYRALGAAQFEEVEWL
                     PGDLTGVPLIAGTVARFECELWRTYDGGDHTIFLGKVLSMEQQTDREGLLVYRGRFQEL
                     TDRPGVPA"
     gene            26818..28200
                     /locus_tag="HHX41_RS00390"
     CDS             26818..28200
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657668.1"
                     /locus_tag="HHX41_RS00390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_310741687.1"
                     /sec_met_domain="p450 (E-value: 1.8e-84, bitscore: 279.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATSRRAVLAPPRTRKGGAQVAPPGPPVTATPRLFLQLVRDRLG
                     LLTSATAAYGDAVRLTIGPKSIYLFNHPDHAKHVLADNSAAYHKGIGLAEAKRVIGDGL
                     LTSEGEVWRAQRRTVQPMFQNKRIAHQDAVIAGEAARLVERLRARVGGPPVDLAGEMTR
                     LALGVLGRTLLGADLDRFHSIGHAFENMQDQAMFEMVSLSMVPLWLPLPGHLRFRRARR
                     DLYRVADRLVAGHPDGGDDVVTRLLASPAGVDPRPARRRMREDLVTLLLAGHETTASTL
                     SWAFHLLDRHPEVRERLRAEAVEVLGDRPPVYDDLHRLRYTAMVIEEVMRLYPPVWALT
                     RVAQRDDEVGGYHVPAGADVMISPYTLHRHPAYWTDPERFDPERFDPDRAHGRPRYAYI
                     PFGAGPRFCVGNHLGMMEATFVLAMVSRELRLAHVPGRPVVPEAMLSLRVRGGLPMTVH
                     RA"
     gene            complement(28309..29079)
                     /locus_tag="HHX41_RS00395"
     CDS             complement(28309..29079)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893426.1"
                     /locus_tag="HHX41_RS00395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_169979375.1"
                     /transl_table=11
                     /translation="MDEVIERAALRVIENMHENLGEPITIDDMARVAMFSKFHFSRVFQ
                     RVTGLSPGRFLSAVRLREAKRLLASTVMSVTNISHQVGYSSVGTFSSRFTSSVGLSPSR
                     YRVLGSVTPQLLAAGPGATPSGATATIAGEISSPLPDRPVFAGLFPERILGGRPVCYTL
                     LDRPGPYVLENVPPGRWHLIAQSAAEGHEDAFGTPGGEDEAQCISCSGPITVRPGAGAQ
                     VADVRLRPMRPLDPPVLLALRDLLSPVGAARQAC"
     misc_feature    29236..29245
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.55"
                     /tool="antismash"
     misc_feature    29278..29293
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.31"
                     /tool="antismash"
     misc_feature    29283..29297
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.85"
                     /tool="antismash"
     misc_feature    complement(29285..29298)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.29"
                     /tool="antismash"
     misc_feature    29285..29299
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.87"
                     /tool="antismash"
     misc_feature    29290..29305
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.39"
                     /tool="antismash"
     gene            complement(29365..30210)
                     /locus_tag="HHX41_RS00400"
     CDS             complement(29365..30210)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621715.1"
                     /locus_tag="HHX41_RS00400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metallophosphoesterase"
                     /protein_id="WP_182904366.1"
                     /transl_table=11
                     /translation="MTGRRTKNGRLLAISDLHVAHPENRALVESLRPGAPGDWLIVAGD
                     VGERISDVEWALATLRDRFAAVVWTPGNHELWTTPGDPEPLRGEERYRRLVQVCRRIGV
                     LTPEDPYPVWTGEGGPATVVPLFLLYDYSFRDPHTTKEESLAQAYRLGVVCTDEILLDP
                     HPYPSREAWCRARLRETESRLDARDPDLPTVLVNHFPLLREPTRVLRHQVFAQWCGTEH
                     TADWHLRYHASAVVYGHLHVPRTTWHDGVRFEEVSLGYPRERRHHAGPPAPRQILPAAA
                     "
     gene            30418..30981
                     /locus_tag="HHX41_RS00405"
     CDS             30418..30981
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893377.1"
                     /locus_tag="HHX41_RS00405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SigE family RNA polymerase sigma factor"
                     /protein_id="WP_182904367.1"
                     /transl_table=11
                     /translation="MAEARDDGFSRYARHAWPALRRTAFLLTSDWHEAEDLVQRTLIAL
                     HRHWDRLERHDRLSGYARAIMIRLVYSDRRSHRWSREVLHELPPEPEPLADPYTLVVDR
                     ILLMNALAGLGPRQRAAVVLRYWEDRSVEETASAMGSEGSTVRSQTVRALATLRTALTA
                     ASDGTAGEARRNAEDATRAAVPGR"
     gene            31020..31589
                     /locus_tag="HHX41_RS00410"
     CDS             31020..31589
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017598710.1"
                     /locus_tag="HHX41_RS00410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5987 family protein"
                     /protein_id="WP_182904368.1"
                     /transl_table=11
                     /translation="MPPRAPADDNPRTTTLEAFADTIVPGEKRYPGDLAVAGAAEGAGA
                     VQAGAIELLEWNATGVTEGLDDYARLLGDHARDYAAEHGLTLDDSLPPFVALTFEHRTA
                     LVRRLTAPDHPEKAFWVLLALFSNMAYDSAAHTSTAEAIAAGHPGLLAMGIARPGDDGL
                     WRFPAHSYGRPLARLHPDTTPSGSPA"
     gene            31586..33247
                     /locus_tag="HHX41_RS00415"
     CDS             31586..33247
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893423.1"
                     /locus_tag="HHX41_RS00415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_182904369.1"
                     /transl_table=11
                     /translation="MTSTERTDVLVVGSGFGGAIAAYHLAAGGARVVVLERGPWLGAQD
                     FEHDFKLGSSYTRAFDFVVGDGMSVLGGNCVGGGSVVYFAAMPRAPRFVFERHGTIGRR
                     MWPASVSRDTLDPWYDRVAESIPVTTQDWNDVTYAGGLWAAACDHSGRTANPVPVAIDN
                     AKCVNCNWMMAGCRFDAKRSLLTNYLPAALAHGAQIRPLHEVQRIERNHDGSYRVHYDL
                     IDEEDYRIRYDGGAIDAKIIVLAAGAGATPVILQRSEATLGAMPHAVGRYFSGNGERLN
                     TAVLNEDRVRDVLGLSRGDGLAYAANQIGKGPTVANWDRLDGSLPEFTRYSLEQLYFPP
                     GLGTILAQVADAAPGESTWFGVKKKEMLRRWQSWLIIFQMIEDANEGVFGPPPAKGNAD
                     RVSQQMLGVGRLKYDPAETTLRAWAMADAEVKEILERDGLATVTAWTNEVIGAYTVHPL
                     SSCRIGDDPATSALDDRNELRGHPGIFVTDGSAVPGALTVNPAMTIAALAERAIPGIVR
                     AAQDRGVDVTYGAPAPDGGTSGRRGVADLLPSLTRR"
     gene            33260..34351
                     /locus_tag="HHX41_RS41545"
     CDS             33260..34351
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893422.1"
                     /locus_tag="HHX41_RS41545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_182904370.1"
                     /transl_table=11
                     /translation="MGAVLARATLPGTLAQVRHVAPVRPNAAPDLVRRVYAQVERDFGM
                     LAPPVILHSPAPPVLAACWLALRESLLARGAVARQVKEAVATAVSRGNSCPYCVDVHRA
                     TLDALVRRGGAAADPRTSRIEEWARAAARRGEAASHALPVPPDQAAELIAVAVTFQYLN
                     RMVNVFLGDSPLPPGVPVRARKGLMRLFGLLIAPAASRAATPGDSLSLLPDAPLPPDLS
                     WARDVPHVAGAFARAAAAVEVAGRRSVPEPVRDLVTDVLDGWNGEPPGLGRAWVAGAVS
                     VLPDRHRPAGRLALLTALASYQVDEGVVDEFRRAEPDDRTLVELTAWAAMSAARRAGAW
                     AHEARPHVGDRDTATTSSERTAR"
     gene            34348..35151
                     /locus_tag="HHX41_RS00425"
     CDS             34348..35151
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893421.1"
                     /locus_tag="HHX41_RS00425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIGR03084 family metal-binding protein"
                     /protein_id="WP_182904371.1"
                     /transl_table=11
                     /translation="MTQLETVLRDLTAEGEQLDRIVAGLDPDQWNLPTPAPGWTVRDQI
                     AHLTFVFRLAATAASDPAAFEAMTAPAKGNFDAAVNAALKMFENDTPAELLAKWRSVRA
                     EVVEALPAVPADATVPWLVNPLPPVVLACAGIMEQFAHGQDIADTLGVELERTDRLGHL
                     VVFAVLTRDFGYLSRGLTPPAEQFRFEITAPSGQVWAYGPEDAEQRVSGPAADFCLLVT
                     RRRHRDDLAVTAVGAEADRWLDIAQAYRGPAGQGRRPGQFAPARV"
     gene            35177..36265
                     /locus_tag="HHX41_RS00430"
     CDS             35177..36265
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX41_RS00430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_182904372.1"
                     /transl_table=11
                     /translation="MRPTPAGFRTAGETPGTAGEVAGCLDGTVHLAYARASAADPPVVA
                     AGFSAEAALSRARARARALGLLREGPAPRATPGGGGRALRLSDFVPHPIAPQLIAPHAA
                     APHAAVPHATVPHPTGSGGPLVAGRGLLTGAGYRLPGEVVWLREHGGPVEPTAIGVVDD
                     CAPAGVADVLAHDAVLRWRAASRRPPLRITPYLGGLLPPGVAEAASGLGLSISAYVLPA
                     GEVRTVLVRVRGAATTTAAACGRTLGAAVREAFLLAVAAGAQPGQAVPDLGAPSRLVAW
                     RHEDGHPADLERTAVDADPGIVDEPAGPVPSGWAGVAYRRFGHEPILVEAGESREAVKV
                     VCPGASCYRRERPGIEVPCPVR"
     gene            36327..37313
                     /locus_tag="HHX41_RS00435"
     CDS             36327..37313
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX41_RS00435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_182904373.1"
                     /transl_table=11
                     /translation="MDVSVIGISPEAAEIYRYFLRCKGEGVGSVPEALGLSADTVEAAV
                     ETLSRLSLLDIADRHRVVATEPRIGIERLVEKRLNELNAEIRRVLAARDAIAVFMEDKH
                     EGDRAATVLDIERVEGVERVRQRIDDLAFFSYKETLCLHPGGPFSRVMIESALPLDTRS
                     LRRGLAIKGVYHPAALDDPFMVSYLRELVSLGAEVRVTDQPMDRMLIYDRSAAVVPIDP
                     KESAKGALLVREPGLVSQLVIYFDGVWKSATDFRDIMEPTTMEPALSEMEQRVLAVMAT
                     ADKDEIAARELDVSVRTYRRYVADLMARLGAVNRFQAALRAKEENWI"
     gene            complement(37347..37577)
                     /locus_tag="HHX41_RS00440"
     CDS             complement(37347..37577)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX41_RS00440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_182904374.1"
                     /transl_table=11
                     /translation="MKTLVSSPTASWSTLKWAIALASGALACGLAAGTAGMASTAGGAG
                     VADDGPRITVLADGNDGNTWGSPVQYGNTWG"
     gene            37819..39435
                     /locus_tag="HHX41_RS00445"
     CDS             37819..39435
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658021.1"
                     /locus_tag="HHX41_RS00445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_169979357.1"
                     /transl_table=11
                     /translation="MSISELDVAPADLPPRTPPERPARSMGALREELARLRARTVAGRP
                     DGVARQHALGKRTARERLDLLLDEGSFVEIDIYRRHRAQGLGMDGRRPHTDGVVAGSGT
                     VHGRRVFVYAQDFTVFGGSLGEAHAEKIHKVMDLAMSTGSPFIGLNDSGGARIQEGVMS
                     LNGYGGIFRRNVQASGVIPQISVVLGPCAGGAAYSAALADFTFMVQGTSQLYLTGPDVV
                     EAVTGQRVTHAELGGAQVHGTRSGVAAFVHDDEEACLAEVRYLLSMLPGNNLEPPPAAP
                     PCDASRDTRPRLAEIVPAEPSKPYDMREVIAELVDDGDFLELHEGWARNVICALARVDG
                     AVVGVVGNQPLVLAGVLDADAAQKAARFVRFCDAFNIPLVTLVDVPGFLPGTDQEYAGI
                     IRHGAKLLYAYCEATVPRIQVILRKAYGGAYIVMDSRSIGADLSLAWPTNEIAVMGAEG
                     AVNVVFRRELAAAADPAGLRAELLARYAGELVHPQYAAERGLVDDVIDPVQTRSAVARG
                     LAMLRDKRKPGAQRKHGNVPL"
     misc_feature    39643..39659
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.33"
                     /tool="antismash"
     gene            39788..40051
                     /locus_tag="HHX41_RS00450"
     CDS             39788..40051
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893371.1"
                     /locus_tag="HHX41_RS00450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_169979814.1"
                     /transl_table=11
                     /translation="MLVQLTMRRTDGQAAPGSPVDGIRVLALLPGSWHKHLEQVAGDIV
                     IRIRAEGTTAGGVRAEVARILTSPEVSHLELVACRPLEGPRQ"
     gene            40076..40837
                     /locus_tag="HHX41_RS00455"
     CDS             40076..40837
                     /NRPS_PKS="Domain: ACPS (117-179). E-value: 1e-08. Score:
                     27.0. Matches aSDomain:
                     nrpspksdomains_HHX41_RS00455_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013786.5"
                     /locus_tag="HHX41_RS00455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_169979355.1"
                     /transl_table=11
                     /translation="MIASVVAAGECHVWWADPRLETIDTLVRDLSANELRRAARFRREP
                     DRRRFLTGARLLREAAAERLGVRPADVVVDRTCPDCDRYHGKPRILTEGETLHVSISHS
                     GDRVAVALTAVGPLGVDVEAVPATPVDDLARCALTETERRALVALPEHARYEGFARIWV
                     RKEAALKATGHGLRISPDRVEVTGPGESPALLSWPLDVPPAAVRIHPLDPGPGYVAVVA
                     VLGGDHGITVREADAALLRRRAGFETARQAA"
     aSDomain        40427..40612
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHX41_RS00455_ACPS.1"
                     /evalue="1.00E-08"
                     /label="HHX41_RS00455_ACPS.1"
                     /locus_tag="HHX41_RS00455"
                     /protein_end="179"
                     /protein_start="117"
                     /score="27.0"
                     /tool="antismash"
                     /translation="LGVDVEAVPATPVDDLARCALTETERRALVALPEHARYEGFARIW
                     VRKEAALKATGHGLRIS"
     gene            40938..41660
                     /locus_tag="HHX41_RS00460"
     CDS             40938..41660
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.5"
                     /locus_tag="HHX41_RS00460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_169979353.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.3e-13, bitscore:
                     46.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKGFILIPGPWMGAWAWGPVARRLRGYGHAARAITLPGLADPDG
                     DVAGVGLETHVGTVLSLLEEEDLRDVVLVAHSYSGIVAGQVADRAADRVAHTVFVEAFL
                     PHDGKSMLHAFPERQHAAELRLIEDNGGRWPAPDAAVVGEGQGLTRRQARWLAERLVGH
                     PGRTIAEPAVLTRPLTQQRATYVVCSMEHFGGRVAADVDALRAAPNWRFHTLPTGHWPM
                     ISAPGRLALLLHRIAGRA"
     gene            41721..44264
                     /locus_tag="HHX41_RS00465"
     CDS             41721..44264
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0015616 - DNA translocase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888899.1"
                     /locus_tag="HHX41_RS00465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA translocase FtsK"
                     /protein_id="WP_182904375.1"
                     /transl_table=11
                     /translation="MATRTSGQGSGKRPASRSGSRTASPKRSPAGSRGRAAPRPAPKRP
                     VATGQDPVSWFFLIIGKIFISMWMLVANGVGKAARGLGQGARDLDPVHRRDGQGLSVLA
                     GAIVLAALTWRDTKTGFAAFVDAVVRGTVGALAWGVPVLLALLAWRLLRHPDQNAETGR
                     MGIGWTALLAGILGIVHVAHGTPYPSGGPDDGMDNVSAAGGMIGFIVSAPPSSILPAFI
                     TIPLLLMLSGFGLLVITATPVHRIPERLAEIQHMLFQRPDETGEPRKSPAPSRKRTRKQ
                     QGGGRDAAEGGDGVKPYDTPVLSEKDHAPEIVPGLVDEAVESAEPTEPEMRLPKTAPQP
                     PLPTPAPRKVEQLVLSSQEGPYTLPDVAMLRPGSAPKQETKANRTVVNALTSVLEQFAI
                     DAQVVGFTRGPTVTRYEIELGPAVKVEKVTALTKNIAYAVKSADVRILSPIPGKSAIGV
                     EIPNVDKDLVSLGDVLRSQVAQADHHPMIVGLGKDVEGRTIVANLAKMPHILIAGATGA
                     GKSTCINGLISSILLRATPDEVRMVLVDPKRVELSAYEGIPHLITPIITNPKKAAEALE
                     WVVGEMDRRYDDLAASGFRHVDDFNKAVRAGKLVPPPGSERVYQPYPYLLVIVDELADL
                     MMVAPRDVEDSIVRITQLARAAGIHLVIATQRPSVDVVTGLIKANVPSRLAFATSSLAD
                     SRVILDQPGAEKLVGQGDALFLPMGASKPMRLQNAFISEKEIAEVVGHCKAQMQAEYRE
                     DVAAPATAKREIDEEIGDDLDLLVQAAELIVSTQFGSTSMLQRKLRVGFAKAGRLMDLL
                     ESRNVVGPSEGSKAREVLVKPDELPGLLADLRGES"
     gene            complement(44280..44468)
                     /locus_tag="HHX41_RS00470"
     CDS             complement(44280..44468)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX41_RS00470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_182904376.1"
                     /transl_table=11
                     /translation="MILVDARTGREVEPVVVDAHMGERVDGPGHFFAAGPAAGPIIGQR
                     YEGVARLPAPAPAAGSA"
     gene            44504..44758
                     /locus_tag="HHX41_RS00475"
     CDS             44504..44758
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX41_RS00475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_182904377.1"
                     /transl_table=11
                     /translation="MPRARRTTPLSARTVDNSVDTTVHTTVDKTVAGRTVVTCRLEGTF
                     PGSPVDLDYRFDLDDAERISRLEIVVSRPAPETAMEVTG"
     gene            44893..45612
                     /locus_tag="HHX41_RS00480"
     CDS             44893..45612
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024855.5"
                     /locus_tag="HHX41_RS00480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_182904378.1"
                     /transl_table=11
                     /translation="MAEARERAGLTVRQLGERTRIRETVIERFEQDDFSVGDFYARGHI
                     RTIASDLGLDPDEVLRQYEQENADGASPVRASAVFRGDVGERARRAPGWTKAAAVALAI
                     VVVVVVARMLGGSGEKAGPTAAQLPVTAPHAHERQAKGHDRKSLEEAFGPGRVVVKVTT
                     RKPAYVDVKDAKGKEIFRGTLPEGKTTAYSAKDKVRMFIGDAGAVRLEVNGRDLGTPGR
                     DGQMIRRTFEAGGPSPR"
ORIGIN
        1 ctcgtcgagc gtcccgaccg cggacatatc gcccacgagg acgtcgagca gcccccggcg
       61 gccggccccc gggcggtgca gcagcgcgaa ggcgggagga tccggggaga gcaccttgtc
      121 gaggagtcgt tcggccgtca tcgctgtccc tccgaactcg aggaaaggcc cggcaccggg
      181 gcgaggcccg gcgtggggga aaggtccggc gccgcggaca ggtccgccag cacctgctcg
      241 gtcgtgacgg tcacaccgca ccgccgggcg gcgtagtcga gcgtcatgcg gtggtcggcg
      301 gcggtgaagt ccgcgatggc gtcggccacc aggaagggct ggatgtcgtt ggtgaaggcg
      361 tcgaccgcgg tcatcaggat gcccacgtgg gcgtacaccc cggcgaggat cagctggtcg
      421 cggccgctct cccgcatccg gctcagcagc gtggtcctgt ggaaggcgct gtagcgccat
      481 ttggtgaaga gccagtcgcc gggggcgggc gccaccgcgg cgacgatgtc ccggtgggac
      541 ggctcggccg tcatgccggg gccccagaac tccctgagca gcccccgctg ctcctccgtc
      601 atgtctccgg gctgtccggt gtacgccacg gggatgccga ggcgggcaca ccggttccgc
      661 agcgccgtcg cgttgccgac caggtcgacc accggaggcc ggcccgcggg gaacggctcc
      721 aggaagaagt tctgcatgtc gtgcagcagc agcacggccc gtctcgaatc gaccgtccag
      781 gacgccgtgt tccccggcag ttctccggcc tccggcatgg aatacggtgc gatctgtgga
      841 attcctgcca tcgaaatcct cttgtgtgcc gtgatttgtg atctcgttat caggcgccga
      901 gggtcgcgcc gccgtccact gtcaggtgtt gcaatgtgat gtgaccggct ctttccgaga
      961 gcaggaaggc gacggcctcc gcgatgtcgg ccgggcgcgc gatctttctc agcgggatcc
     1021 cggtgcgata gaggtccggg gcgccctcga tggaggcccg gtgaccgtca tcgtcgtgcc
     1081 acagcgaggt gagcatcgga gtgtcggtcg agccgggcgc caccacgttg cagcggatgc
     1141 cgtagcgggc gacctccagg cccaggttct tggtgaacat cgtcaccgcc gccttggagg
     1201 cgccgtaggc ggacattccg atgcgggccg tgtgtgccgc gttcgaggcg acggtgacga
     1261 cggcgccggc ccgccgcggc accatcctgt tcaccaccgc acgtgagacg tggaagacgc
     1321 cggtgacgtt gaccgcgaac gtcgcggccc agtcgtcgtc cgacagcgtc ctggcctcgc
     1381 ccacgcgtag cacgccggcg gcgttgacca gccggtcgat cgggccgagc cgccgctcga
     1441 cctcgtccac gaccgcctcg acctgtggcg cggaggtgac gtccgcggtg aacgcggccg
     1501 cctccagccc gtcggcgacc agcttgccga cgacggtgcg cagcgcgccc gcgtcgcggt
     1561 ccacggccgc caccggcacg ccgtcctcgg cgagcacccg ggcgacctcg gctccgatgc
     1621 cgccggcggc gccggtgacc agggcgacca tcacgcgctc ccggcggcgg tcgcggcggc
     1681 gttcgccgag gcgtctcctt cacgtgcacg acgtgagtga acgcgggggg ccggccggtc
     1741 ccacgtcgtc ccgcccgtcg cggaaagggg gcggggaaac cgcgaaatgt ttttcatggc
     1801 agaactgtgc ggcccggcgt aagtcgccaa caaggcgaat gaaaggcagc atgttgcccg
     1861 ccgatagccg tttcctgcca acaccggccc gcctgggaaa gagcggcctg tggtcccctc
     1921 gcgacgggcc cggaccgttc gccgtgaatt gactcaaggt cagaagaatt gtcatctcac
     1981 gggttcctcc cgggccggga cgagggctgg caggaagctg taccacccgg gcatcttgct
     2041 gccgccgccc tgtctggccg gtgccacgca aacgcgcgag attgccgatg cggagatccg
     2101 tactcgcacc aagggagagg catgatgact tcgtcgtcga ttcgccgcgt cacgatcatc
     2161 ggctgtggtc tgatcggcgc ctctgccgcg ctcgcgttgc gcaaggcggg cgtcgaggtc
     2221 gcgctgtccg accgcgaccc gcacgcggtg gccgtcgccg agcggatggg cgcgggcgtc
     2281 gcactgaccc ccggcgctcc cgcggcggac gtggtggtcg tcgccacgcc gccgtccacg
     2341 gtggccgccg tgctgcggga cgcccaggcc agggggctcg gcgccgtcta caccgacgtc
     2401 gccagcacca aggcccgcgt cgtcgccgag gccgagcggg cgggctgcga cctcaccgcg
     2461 tacgtgccgg ggcacccgat ggccggcgcg gaggcgtcgg gccccctggc cgcccgggcg
     2521 gacctgttcg ccggacggcc gtggacgctc tgcccgcttc ccacgacgcc gctgcggccg
     2581 gtgcgcgtgg tggccgaact ggtggcggcg tgcggagcgg agcaccggct gctggcgccg
     2641 gacgtccacg acctggccgt cgccgcgagc tcgcacgcgc cgcacctggt ctcggcggcg
     2701 ctggcggcga ggttcgccgg cgcggacgag accacgctct ccctggtggg gccgggcctg
     2761 cgggacgtca cgcgggtcgc gggtggggcc cccggcctgt ggtgcgacat cctccggcag
     2821 aacgccgagc cggtcgccgc cgtcctggag gcggtggcgc gggacctggc cgccgccgcg
     2881 gcggcgctgc gcgacccgga gggcgggcag ttgctcgccg acctgctcac gaagggcaac
     2941 gacggccgcg cgcgcatcgt cggcgggggc gcggagcaca cggcaccggc cggcgccctc
     3001 gcggcctgag ccgcgccccc gagacgcccc cgagacgccc ccgagacgcc gccggcgcct
     3061 cgcggcctga ccgcgcttcc tccgagagcc caccggcggc gatcggtggc gcccccgccc
     3121 ctggacggag cccggggctg cgcaaccaga aaggtgtgcc gcccgcgggg ccggtgcgac
     3181 agtcgaggag acccagcggc ggccaccgca ccgcactgca ctgcaccgca ccgagctgca
     3241 cccaccgagc tgcaccgcac cgaggctgca tcgcagcgca ctgtgccgca cggagctgca
     3301 ccgcagcgca ctgtgccgcg tcgcgggcgc gggcgttccg cccgccgcca tgtgccgtga
     3361 gctgggacgc gaggagcggc ttcagcgccg acggcacgag gaggaaacga tgttgacgac
     3421 cggggttccg acacgggagg aactggttcg gcgcgcgtcc gaactgctgc cgctgctgcg
     3481 cggccacgcg gactgggcgg aggagaaccg gcggatccac gacgagtcga tcgaggccct
     3541 ggccgacgcc ggcgtcttca agatgcgggt gcccgcccgc tacggcggct acgagtgcga
     3601 cacgcggacc ctcctcgaag tggcggccga gctcgggcgg gccgacggct ccaccgcctg
     3661 gacggcgtcg gtctactgga tcccgacctg gatgacctgc ctgttccccg acgaggtcca
     3721 ggacgaggtg ttctcgacgc cggacgtgcg ggtgtgcggc acgctcagcc ccaccgccat
     3781 ggccgccccg gtggacggcg gcgtcgtggt caacggcaag tgggggttcg tcagcggcgc
     3841 ctggcacagc cactggcagg agatcgtggc gatccaggtc ggccccgagg gcgagcccat
     3901 gccgatcatg gcgctggtgc cgatgtcgga cctgcagatc gtggacgact ggcacacctc
     3961 cggcctgcgg ggcaccggca gcgtcaccac ggtcgcccag gacgtgttca tcccggccga
     4021 gcgggtgctt ccgctgcccg cggtgctcat ggggcagtac gcgtcgaagc tgaacgccgc
     4081 cagccccatc taccggacgc cgctgctgcc ggtcgcctcc gcgtcctcgg tcggcacggt
     4141 gatcggcctg gcccgggcgg ccagggaggc gttcttcgag cgcctgccca accgcaagat
     4201 cacctacacg cactacgaga gccagagcga ggccccgctg acccacctgc aggtggcgga
     4261 ggcgtcgctc aagatcgacg aggcggagtt ccacgcccag cgcctgaccg gcctggtgga
     4321 cggcaagggc gtgacgggcg agcagtggac gctggaggag cgggccaggg cgcgcgccga
     4381 catgggcgcg gtgtgccggc tgggcaagga ggccgcggac gtcctcgcca tggccagcgg
     4441 cggttcctcc atttacaccc aggtgccgat ccagcggatc gcccgtgaca tcaccgcggt
     4501 gaacctgcac gcgctgatgc accccaacac caacaccgag ctgtacggcc gggtgctgtg
     4561 cggccaggag cccggcacct tctacatcta gaccacaccc cctccgccga aacggttccg
     4621 cggcccgacg acgtgccgcg gaaccgtttc gtatgtgtgc ccggagtcct tccggcgtgc
     4681 cctgagggcg ggcgaaacgc ccgggcagac ggaaaagccg gaggcgtgcg acacacgcct
     4741 ccggccacga tgcgccggct cggtcacgcg gcgggcgaga ccgccgcctt ccccgcgacc
     4801 atgcggacca gcgcgtcgag gttcgggtcc tcctcgaaga cgtcgccgac gtcgacgctg
     4861 acgccgagct cctcctcgat gcgggacacg aggcggaccg cggcgatcga ctcgccctcc
     4921 aggtcgaaga aggtcgcgtc ctcacttccg tccggcacgt cgagcacctg cttccagatc
     4981 tccgcgacct tggcctcgat gaccgggaga acaagctcgc cggggtgatt gccactcata
     5041 cggtgtcctc cccaaacgtc cacgatggcg cgcatggcgt cctgctgcct gctggctgcc
     5101 ctcacagcat cgcaaccgcc gggggtcgcg gcacctccca gagtgcgagg tcaggtcctg
     5161 accaccggtc ccagtccgtc cgagatccgc agcccgccgc gggcgtcggg ccgggcccgc
     5221 cgcgtacggg aaagccggtc gcgcacctgc cgtccggcgc gcgggtcgat ccggtcagcg
     5281 aggtcgagcg tgcgggtcat ggcgtcgtcg gcctcgtcgt agtcgcccgt ggcgtacaac
     5341 gcgtcgctca gcatgatcag ggtctgcgct tcgagcagcg gcatctgcat cccgcggaac
     5401 agggaggccg ctctgcgtag atgcaccgcg gcctggtcgt tctcgccgtt cgcgacggcg
     5461 acctcgccga gccccgacat cacgcgggcc tccgcgagcc ggtgccgcga gctggtcgcg
     5521 agccgcaggg cctcgcgcag cgtctcgccg gcctcggcga tcctgccctg gcgcagccgg
     5581 gcgacgccca ggccgtgcag ggcgaacgcc tcgccgatgg agtcgccgat gtcccgcacg
     5641 accgtcagcg actcctcgaa ggcgccggcg gacaggccga actcgcccgc ctgcagatgc
     5701 gcctgcccca tccggtgcag cacctgcgcc gtcaccctgc ggtcgccccc ggccttgctc
     5761 cgcgtcagcg cctcggagag cagcgacttg gcgctgtcga ggtcgtcgca gtcgagccgc
     5821 acctgggcga ggctgtgcag ggtgtgcgcg gcggagacgt ggtcgcccgc ggtgtggaac
     5881 acctgcagcg ccttctcgta gttggcgacc gcctccgcga accgcccgtt gatgcgttcc
     5941 aggaccgcga tgctgcggat cgccagggcg atcctgagct cgtcgccgac ctcctcgaac
     6001 agccgcaccg ccgcgtccag ctcgcgcctg gcgtcgtcga accgctgctc gctgaacgac
     6061 agtgagccga tggtgtacag catctcggcc tggccgcgcc ggtccccggc ctgccgcgcc
     6121 gcctccagcg cgagctcgtg ggtctcccgc cagtcgtcca ggtagacccg cgactcgaag
     6181 aacatcgcgg cgttcgcggc gagccgccag cacagctcga cgaagcccgc ctgcgccgcc
     6241 tgccggatgc cggagaccag caggtgacgc tcccgctcga accacgccat cggctcggcg
     6301 acgagctgct cgacgagctt ttccggcagc ggccggggga tcacgctctc catccgggcg
     6361 agcacgtcgg agccgaactc ccgcgacctg gccgcgtccg tcagcgacag cagcgagccg
     6421 agcacccggg acaacgcggc cttccgctcc gccaccggct cctccgcggc caggcgctcg
     6481 cgcgcgaaca ccttgacgag gtcgtggaac cgatactggg tgtgcgtccc ccggccgacg
     6541 gtcacctcga cgaggtgggc gtcggcgagg ttgtcgagca ggtcctgggc ctcgatgaac
     6601 gagcggtcga gcagggccgc gccggtccac acggagaata cgtgggagtc gaggatcgcc
     6661 agccgccgca gcagccgccg cgcctcctcg ctgatgttgt cgtaggtgag cgagaggctg
     6721 gcccggatgc ccatctcgcc gtgcatcagc tcgtcgagcc tgcgtgtctc gtccctgagg
     6781 cggtcgacga gttgttcgac ggtccagtgc gggcgcgccg ccagccgcgc gccggcgatg
     6841 cgcagggcca ggggcagatg gccgcacagg tcggcgaggg cctcggcgga gctctgctcc
     6901 gacgccaccc gcccgccgcc ggccacctgg gcgagcaggt ccaccgactg ggccgagtcg
     6961 aacaggtcca cgtcgatgtg cgtggccccg gccagcccca cgaggcggct gcggctggtc
     7021 acgatgacgg cggaggcggg attgcccggc agcagcggca ggacctggct ctcgctgccc
     7081 acgtcgtcca gcacgatcag catcctgcgg tccgcgagca gcgtccggta cgtctccgcc
     7141 cgctcttcga ggccgtcggg gagcgcggtg ccgggcaccc cgagggcgcg caggaagcgt
     7201 tcgagcacct gcatggggct gaccgggcgg gagaccccgc cgtgcatgtg ggcgaagagc
     7261 tgaccgtcgg ggtagtggtc ggcgacgctg tgcgcggcgt ggaccgcgat ggtcgtcttg
     7321 ccgatgccgg cgcggccggc gatcgcgatg atcggcacgg cgaagcgagc catgccgtcg
     7381 gagacctgcg tcagccggcg ccgtatctcg tcgaggtgcc cgtgccggcc gatgaagtcg
     7441 gcgattccgg agggaagcat gccggggacc gggggagggg cggcgggctc ggccacggag
     7501 atccgcgcgc tatcccgctc cggcggcgcg tcgaggctct cgtccgcggt gaggatgccg
     7561 tgttcgagct gctgcagccg ctcgttgggc tcgatgccca gctcgtcgat catcatccgc
     7621 cgggcgtcgc ggtagacctg cagggcctcc gcctgccggc tggaacggta caacgccgtc
     7681 atgaactggc cgagcagccg ttcgcggagc gggtgctcct ccacgagcct gcgcagctcc
     7741 gtcaccagct cgtggtgccg gccgaggtcg agttcgagct ggacgcagtc ctcgttcgcg
     7801 gcgagcctct cctcgtcgag ccagctcgcg gcggcctgga ccatcctgct ctcgatgcct
     7861 tcgagtgcgg ggccgcgcca gagggacagc gcctcacggt agtgcctgac ggcctcgtcc
     7921 acgtcccggt tgtcgcgcgc ctgccgtgcc ttcagcacga ggctctcgaa gcggtgcgcg
     7981 tcgatctgct cgctgtcggt ccgcaaggcg tatccctggg accgcgtgac gatcatctga
     8041 tcgtggccgt gggcgccgaa caggcgccgc agggcggaga tgcagatctg cacctgggcc
     8101 cgcgacgtgg cgggtgggtc gtccccgtag atggcctcca tgagacggcc gacggcgacc
     8161 ggtcggttgg cctccagcag cagcacggcc aggactgtgt gctgtcgcac acccccgagg
     8221 tcgagtcgtt gcccaccctc cgtgacttcg agggctccta gcaggcgaaa ctccacatgc
     8281 atctccctct gaaactgctg gaccattgca cagtgcggat tacggagctc gctctccgcg
     8341 atatgcgcat tgcggcctca cataaaggct ctctctgggc gatggcagtt tacggaatgt
     8401 ttgcgatgga gccgtgaaca ccggcggaaa cgctgtcagg tgcggtcgcc gccgttctga
     8461 catgtagtcg cccgcgcgtc ccctattgac attgttgtca gggatcgtac agcgcgaaac
     8521 ggacggtggc taggcgaatg cgcggtccgg caggtgaact ccggtgcacg ctcgaatctg
     8581 ctaggacgcc ttacctgttg aaagtcgctt agtcagaaaa gtggccgggt ggccggacaa
     8641 tgcccgggaa aagcgccgag cggccggaga cgccaggtct ccggccgctc ggggggtgag
     8701 tcagtcccag gggttcacgt gggtgttggt ggggctcggc gacgggatgc cggcggggct
     8761 gtgcggctgc acgctccggt ggacgacggt gcgggcgtga gcgtgggaag ccgccgccac
     8821 cgagaccatc gcgcccgccg acgccgcggc cgtgagggcg atgaagatgg agacggcgaa
     8881 tcgcttgacg atgctgctgc tgccggccac ttggatacct ccaccctgtg cgcggcgctc
     8941 cgtacgccga tcgcttacgg gaccgacgct cacacccccc gccatcgagc ccttatcgtc
     9001 gcgcttccgg gatgccatca ccgcaggtcg aaggggtagt gggcggtggg atgcgggggg
     9061 ttgcgccgcc ggctgagggg tgcggcccgg cggcggcccg ggcccccgcg gtgacgggcc
     9121 atggccggac gatgcctggg cgatagcggg gcgatgccgg gccgataacg gggtgcgcca
     9181 ctgtgacagc aacccgggcg gcaaccgcac gcaggcggcg aagcccgggt caccacaagg
     9241 tcggaagacg agagcgttga gccgggccgc aggggtcccg ggattgtgtg gcggtgagat
     9301 gggcattgct cttcaggcgc tggacggcct ctacggccgg ccggccgccg gtgtccgggt
     9361 gcggcttgaa cgcagcgaca acggcctctg gtgtgccgag gtcaaggcgg agaccgacca
     9421 cgagggacgg gtgggggagt ggcgcgggcg caggttcgac cgcgggctgc accgcatcgt
     9481 cttcgagagt gactcgtact tcgtcggcct ggggctgacc gccgcctatc ccgaggtctc
     9541 gatcacgttc cgcatgcatg acgagaccga ctcctaccag ttgcaggtgc tgctctcgcc
     9601 gtactcctac tccgcttact tcggatcgct cacctaagga gccgaccgtg aatctcggac
     9661 gctacagcgg ttcttcacgg gttcccctcg agggccgcgc ctggccggac gcgaccatcg
     9721 gctcggcccc gcgctggctg tcgaccgacc tgcgcgacgg caaccagtcg ctggccgagc
     9781 cgatgtcgcc ggcccggaag ctgatcatgt tcgacctcct ggtggacgtg ggctacaagg
     9841 agatcgaggt cggtttcccg gcggccagca aggacgacca cgacttcgtc cggatgctcg
     9901 tcgagcgcga cctgatcccc gacgacgtcc ggatctccgt tctgacgcag gcaagggacg
     9961 agctgatcga gcgcacggtg gcgagcctgg agggcgcgcc gcgcgccacc gtccacctct
    10021 acgccgcgac ctcgccgctg tttcgcggcc tggtgttcgg catgagccgc gacgagtgca
    10081 aggacctcgc cgtccagggg acccggctgg tgatgaagta cgccgagcgg acgctggacg
    10141 gctgcgacct cggctaccag ttctcgcccg agcacttcgc cgacaccgag ccggacttcg
    10201 cgctggaggt atgcgaggcc gtcatggacg tgtggcagcc ggaggccggc cgcgagaccg
    10261 tcctgaactt ccccaccacg gtcgagcgcg ccacgccgaa cgtcttcgcc gaccggatcg
    10321 agtggatgca ccgcaacctg tcgcggcgcg agcacctgtg cctgtccgtc catccgcaca
    10381 acgaccgggg gaccggcgtc gccaccgcgg agctggccgt catggcgggc gccgaccgcg
    10441 tcgagggctg cctgttcggc aacggggaac gggcgggcaa cgtgtgcctg gtcaccctcg
    10501 ggctcaacct gtccacgcag ggcgtggacc ccggcgtcga cttctccgac ctcgaccgcg
    10561 tccgccgtac ggtggagcac tgcacggggg tgccggtcca tccccggcac ccgtacggcg
    10621 gcgacctcgt ctacactgcc ttctccggct cccaccagga cgccatcaag aagggtctgg
    10681 acgccgtcga aagggaggcc gtccgcaccg gggacgacgc cgcgcacctg ccgtggcagg
    10741 tgccgtacct gccgctggac ccgcaggacg tcggccggac gtacgaggcg gtggtgcgga
    10801 tcaacagcca gtcgggcaag ggcggcctgg cctacgtgat gagcgcctgg cacggcctca
    10861 ccctgccgcg cgacctgcag gccgacttcg ccatgaggat gcaggcgctg acggacgccg
    10921 agggcgggga ggtcgcgccg gagcgggttc tcgaggtctt cgtgcgggag tacgtcgtgg
    10981 attccgccct gccggtcccg ccgtccgtcg aggccagggg gacggtcacc ctgcacatcg
    11041 acgccggctg gttccgcacc ggcccggcca ggacggacac ggtccaggcg gtccgcgcgg
    11101 agctcgcgcg ccggggcctg cgggtgcggg tcgtccacca cacccgcccg gcggccggcg
    11161 cgggcgcggc ggggcgggac gacgcggcgg tctacgccga gtaccgcacg ggcggcgcct
    11221 gttactgggg tgccgggatc gagcgggatg tcgagagggc cgcgctggtc gcggtgtgtt
    11281 ccgccgtcgc cagggccgcc cgcgaccggg ccccggcaac gggcgacggc cagggcgatg
    11341 gcaggagcga tggcaggggc ggcggccggg gggccacgga ggggaacggg cggcacggac
    11401 gccagggcgc cgggcgttcc cggcgggtga cggccggcag gtgaccacgt gaagggcggc
    11461 gacacggcga tggccatggt cgaacgggaa caggaactcg tgctcctcga ggcgctcctc
    11521 gccagcgccg tcatgggcag gggcagggtc gcactggtgg gcggcgcggt ggcgacgggc
    11581 aagagcacgc tgctgcacac gttcgcggag caggccatcg agctgggcgc gctggccgtc
    11641 accgcgacgg gctcgccgct ggagcgggac gttccgctgg gcgtgctgcg ccagctcgtc
    11701 gaggacgcgc cgctggtccc gcaggagcgg gagcgcgcgc tgtccctgct ggaggagggc
    11761 gcgcgggcgg tcgccgcggg cgcggacgag cgccggccgg tggacgccca gctcgtccac
    11821 gcgctctgcg gcgtcctgct cgacctgtcc gagcggtgcc ccctggtgct cgtcgtcgac
    11881 gacgtccacc acgccgaccg cgagtcgctg ctctgcctcg cctacctcgc ccgccgggtg
    11941 cggctcgccc agatcgtggc gatcttcggg cacgccgacc aggcgtggca caccgactcc
    12001 tacttccaga ccgaactgct gcgccagccg cactgccgcc gcgtcaggct gacccggctg
    12061 tcgcgggcgg gggtggccgc gatgctcgcc gcgcgcctgg gcgacgaggc cgccgagcgg
    12121 ctcgccgacg agatgtacgc gcacagcggc ggcaaccccc tcctggtcac cgcgctggcc
    12181 gacgactacg aggagtccgc ccgtacggcg ccggagcccc cggcgggggt cgtcgtcgga
    12241 gagcagtacg gccaggccgt gctgtcgtgc ctgagccgcg gcgaggcgcg ggtggcgcgg
    12301 gccgcccgcg ggctcgcggt cctcggcgag ccccgctccc tcgacctcct gctgggcgtg
    12361 ccggcggccg aggtgaacaa ggacctgcac tccctcggcg ccgccggcct gaccgcgctc
    12421 ggcacgttcc gccacgaggc cgcccggcag gcggtcctcg gggcgatgga cgcgggggag
    12481 cgggcggagc tgcaccgccg ggcggccgag ctgtcgtacg gcgtcggcgc ctccccggcc
    12541 gtggtcgccc ggcacctgct ggaggcgggg cgggtggacg ccccctgggg catcgagatc
    12601 ctggaggagg cggccaggag cgcgctgcgg gccggccagg tcgacagcgc ggtcggatac
    12661 ctgcggctgg cctggcgcgc gtgcgcggac gacacgcagc gggcgaagat catgacgatg
    12721 ctcgtgcggg ccgagtggcg catcaacccg gccgcgcccg ccggccgcct cgccgagctc
    12781 gccgaggccg tgcaccgggg cagcctgcgg ggcggcgacg ccgtcgtgct ggcccgggcg
    12841 ctgctgtggc acggccgcgt ggacgacgcg cgggacgtgc tggagcaggt gctcgaatcg
    12901 ggcgggacgg ccgaccagga gacgcgcgcc gagctcgtcg tggcccggct ctgcctgcgc
    12961 gcggcccatc cccccttcct caccgcgctg gggcacatga cgaaggagga ggggccgggc
    13021 ggcatcgtct cggtgtcggt cagccggcgg ctggagtcgg cgctcgcgct cgcggaggtg
    13081 ctgacccggg ggccgcgcga ggagtacgtc gacgccgtcg agcgcatcct ggaggactcc
    13141 cggctcgacg agatgtcgct ggacacggtc gagaactccc tgctgacgct gacctacgcc
    13201 gggagggcgg agcgggcggc cccgctgtgc gacatgttcg ccgccgaggc gtcggcgcgg
    13261 caggcgccca gcaggcgcgc caggctcgcg gcgatccggg cggagatcgc gattcgccag
    13321 ggggacatgc cggccgcgga gcgccacgcg cgcgccgcgc tgcagatcat cccgatgagc
    13381 ggctggggcg tcgccgtcgg cggcccgctc ggcagcctca tcttcgccct caccaccatg
    13441 gggaggtacg acgaggtgcg cgagcacctg gacgtgccgg tccccgaggt catgttccag
    13501 acccgctacg ggctgcacta cctgcacgcc aggggacgtc acagcctcgc gaccggctac
    13561 cccgccctgg cgctgggcga cttccggcgg tgcggcgacc tgatgacgga gtggaacctc
    13621 gacacccccg gcctgatccc ctggcgggcc gacgccgccg aggcgtgcct gcgcctggga
    13681 cgggtggagg aggcgcgcga gctggtccgg gaccagctgg acgggtgcgt gcccgacgac
    13741 ccccggggca ggggcgtcgc cctgcggctg ctggccgcca ccctcgaccc gggcgaccgt
    13801 ccggcgctgc tgcggcaggc gaccgggtgc ctgcaggccg cgggcgacag gtacgagctg
    13861 gcccgcgcgc tggccgacct cgtggagacc tacgacgcgc tcggcgagta ccgccgggcg
    13921 cggacgatcg ccacctgggc gcaggccgtc gccgcggagt gcggcgtcga gccgccggcc
    13981 tcgtccctga gcccggcgca tcagcagtcg cacggcgccc cgcgcagtgg atcgcacggt
    14041 gggtcgagca ccggatccgg cggcgggccg gagcgcgggg ccacggccac ggcggcccgc
    14101 ccctcggccg tgccgctcgg cgagctgagc gacgccgaac gccgggtcgc gtccctggcc
    14161 gcggccggct gcaccaaccg ggagatcgcg gccaagctct tcgtcacggt cagcacggtg
    14221 gagcagcatc tgacccgcac ctaccgcaag ctcggcatca cccggcgctc cgacctgccg
    14281 ctcgtgctgg agttcggcga gcaggccggg gtctgacacc ggcggcacgg cacccggaga
    14341 caccggaaac accgggagac accggaaaca cccggaaaca ccgggcaacc ggagagttgc
    14401 ccgcccgcct ctcgtggtgt gaccgtcgag gcgggaggcg cacgtggagg acagcaccga
    14461 tctgatcgtc gtacgcggcg acccgacgcc cgaagaactc gcggcggtcg tcgcggtcgt
    14521 ggccgccgtc gccgcgcggg ccgggtccgc cgcggccgca cccgaaccgc ccgccgcgcc
    14581 ggtgtcgccg tgggcctcgg cctgggccgc cttcgcctgg ctcgcccccg gcccccggcc
    14641 ggtcgcccgg ggcgcgtggt cttctccgaa tgtgcgctgg cactggatcg cctgaggaat
    14701 cgccgggcac gagcaccgat cgcgcatttt acgaaaagcc gtaaaggacc cgcggacgca
    14761 tcctgaggaa agtgccgtcg aggccgtccg gggaaatcgc gggaagacga aatgcggctt
    14821 cggcggcgcg gtgccgacgg cgttctgggc ccgtccgggg accacgagtg agaggtgtgg
    14881 catgtcgacg ttgtccggtt cgctccgcag gctggtgctg gccccgtccc tgctcgatgt
    14941 gaccttcgcc gagcgggggt tcccgggctc cccgtccgag gtcacccggc ggctggagac
    15001 gatcccccag gcggtcgtct gcggcttcga gtgggggatc gacgcccgcg accagtggga
    15061 ggtcgagcgc aggctgaaca tgatcgagcc cgagctgcgc ggcttcgcct acgagggcgc
    15121 gacgatggcg ttcacggtgc tcgacgccat gggcggcggg cgtggccgcc gcacccgtga
    15181 cctgctgctc gggcccgggc ggccgcacat cttcctcacc tacatcggca tcggattcgc
    15241 catggcccgg ctgccccggg tgctgtggcg gaaggtgatg cccgacctcg gcggctcgcc
    15301 gtactacccg accatgagct ggctggcggt ggacggctac ggcttcgacc gcgcctactt
    15361 cgacacccgg cgctgggtgg acgagcagcg gatcccgtcg ccctacccct gggagggctc
    15421 gccggactac ttcctccgcg ccgtcgacca gggcatcggg cgggcgctgt ggttcatcca
    15481 cggcgcgcgg gtgggggacg tcgccaccgc cgtgcggcgc ttcgcgagcc accggcaggc
    15541 ggacctgtgg agcggcgtcg gcctggccgc gacgttcgcc gggggctgcg acgccgacac
    15601 gctggcggtg ctgcgccgcg aggccggcga gcacggtccc gaggtggcgc agggcgtggt
    15661 gttcgccgcg aaggcgcgca gctacgccgg gttcgtgccg gcgcacaccg aggtcgccac
    15721 cgccgccctc gcgggcctgt ccgtgcggga cgcggtcgcg ctggccgacg acagcgaggt
    15781 cgcgccggac ccgtccgcgt ccgtgccggc gtacgagctg tggcggggcc gggtccgtga
    15841 gcacttcgcc gcgcgcctgg tggcctgacc cccgacctgt tttccccgtc gcgtcgaatt
    15901 aatttcaccg cgatttcttt cgccatgccc ggaaatagca acagatgggc acttttgaag
    15961 tggtccgggc ccggaggaat atgcgtaaat agcgccagaa tcagccgtat atgcaggatt
    16021 ttatggaggg gcggagaggc aattgacgag tttcctgcgt tcattgagac gccgaatcat
    16081 gacaccggac atctcggaga cgaagctcgc cacccggggt ttccacgtga agagcccgga
    16141 ggcccgggac ctgctcgaga ccgtcggtga gaccttcctc aagggatacg gctacgcgat
    16201 ggaggcgtgc acggtcgcgg aggcggagga gcgcctggag caggtgccca cccggttccg
    16261 cggcttcgcc tacgagggcg ccggcatggc cttcgccatc ctcgacggga tgccgttcgg
    16321 cggtgggcgg gtcgaggagt tcctcgccgg gcgcggcgga cggcacaact acatgatcta
    16381 cgtcggcgtc ggctgggcga tggcccggct gccgaggttc ctgtggccga aggccgagtc
    16441 gctcgacccg ctgctgcgct ggctggcgct ggacggctac ggcttccacc aggcctactt
    16501 ccgcaccgac cagtacgtcc acggacagta ccgcgacccg gccttcccct ggccggccga
    16561 cgccacgcgg ccgtacgcca accgggcgat cgaccaggga atcggccggg ccatctggtt
    16621 cgtcgccggg accgacgcgg agcggtgcgc ggacctgatc gaccggttcg acccgtcccg
    16681 ccgcgccgac atgtacgcgg gcgccgggct ggccgccacc tacgccggcg gcgcggccga
    16741 ggaggagctg ctgacgctgc gggagcgggc gggcgagcac cgcccgctgc tcgcgcaggg
    16801 cgccgccttc gccgccgagg cccgggtccg tgccggcctg gtcgtgccgc acacgcgcct
    16861 ggccgccgag atcctctgcg gcctgcccga ggaccgggcg gcccaggtca cccagctggt
    16921 ccgcccgccg cagccgctgc gggacggcga cccgcccgcc tacgagctct ggcgtcagtg
    16981 catcgccaac gaattcgtct cccttggagg tgttacccag tgaccgcgac acttggctgg
    17041 ctgcgcaggc agacagcggg gatcgtggcg ctcgtgctga tcgcgaccgc cttcctgatc
    17101 gcccgcctgc cctcgtactc cgccgcgcag acggcggaga cggcgagcaa gtactcgttc
    17161 acgccgctgt ccatcgccct gccgagcggc tacgaccagc agtcgatccg aaaggtcaac
    17221 aaggactaca cgcacatcga cgcctggatc tcctcggtcg gggcagcgat cgcgatgaac
    17281 gacctcgacg gcgacgggct gtccaacgac ctgtgcctcg tcgacacccg catcgaccag
    17341 gtcgtgatca cgccgacgcc gggcgccaag tcggagcggt acgccccgtt cgcgctgaac
    17401 ccggccccgc tgccggtcaa cgaccacatg gcgccgatgg gctgcgtccc cggcgactac
    17461 aacgaggacg gccggctcga cctgctcgtc tacatgtggg gccgcacgcc catcctgtac
    17521 ctcgccaaga cgggcgcgaa ggggctgtcg gccacgacgt acaagccgac cgagctggtg
    17581 ccgggcgtga acgtcaccaa cggtgagtac accggcccgc agtggaacac caacgccgcg
    17641 accgtggccg acttcgacgg tgacgggcac gacgacatct tcatcggcaa ctacttcgcc
    17701 gacggaccgg tgctcgaccc cacggtctcc ggcggcgtgc acatgaacca ctccatgtcg
    17761 aacggccaca acggtggcga gaactacttc ttccgctgga ccggcgccaa gagcggcgac
    17821 aagccggcgg cgacctacca gaagctcgac gacgtgctgc ccgaggaggt gtcgaagggc
    17881 tgggagctcg gcgcgtccgc caacgacctc gacggcgacc tgctgcccga gctgtacctg
    17941 gccaacgact tcggccccga ccggatgctg tacaaccgct ccaccccggg acacttcaag
    18001 ttctccctgg tcgagggcgt ccgctcgccc ttcatcccca agtcgaagag cgtgggccac
    18061 gactccttca agggcatggg cgtcgacttc ggcgacctga accacgacgg catctacgac
    18121 atgttcgtca gcaacatcac cacctcctgg ggcatcgagg agagcaactt ccagttcgtc
    18181 gccgacgtga agaaccagag cgagctgcgg gagaagttcc gcgagggcgt ggcgccgtac
    18241 cgcgacgaga gcgcgccggc gcagaccgcc tggtccggct ggggctggga cgtcaagatc
    18301 gaggacttca acaacagcgg tgagccggcc atcgcccagg cgaccggctt catcaagggg
    18361 cagaccgacc gctggccgca gctccaggag ctggccacgg ccaacgacca gatgctgcag
    18421 aacccgacct ggtggccgaa cgcccgcgcc ggggacgaca tcgccggcaa ccagacgctg
    18481 cacttcttcg ccaagggtcc cgagggccgt tacatcgacc tcgccccgca gctcggtctc
    18541 aacgtgccgg tgccgacccg cggcatcgcg accggcgacg ccgacggcga cggccgcctg
    18601 gacttcgccg tggcccgcca gtgggacgcg ccgatcttct accacaacca gagcccggcg
    18661 cagggcgcgt tcctcgggct gcgcctgacc cgcgacgaga agcccgccga cggcgccctg
    18721 cccgcggccg gctcgccggt gaccggcgcg caggtgtgcg tcatgacccc cgacggccgg
    18781 aagttcatca gccgggtcga cggcagcagc ggccactccg gccgccgcac cacggacgtg
    18841 cacatcggcc tcggccagaa cgtcaccggc ccggtgaagg tgcttctgca gtggcgtgac
    18901 cgcaccggac aggtgcgtga acaggatctc cagctcaccc cgggctggca ctcgctcaag
    18961 ctcggccggc aggccaagga gaagtgatcg gacatggctg agaacacgcc cgtcgcgggg
    19021 ccgcgccacg accccaaggt ggtcatcgcg ctgcgcaact tcgcgatctc gatttcggtc
    19081 ttcaacatcg tcggctacac gatcctcggg ttcgagcagc cctggctgtg gcccttcatc
    19141 gccctcgcca ccgggtacac caccgagatc gtcctggagc ggatcggctc gcgggccgag
    19201 gggcggcccc cgcgctacaa gggcaacggc ctgcgcgggc tgatcgagtt cctctacccg
    19261 gcgcacatca ccagcctggc catgaacatg ctgacctacg tcaacgacca ggtcctggtg
    19321 ctcgtcttcg gcgtcgtggt ggccgtcggt gccaagtggg tcctgcgggc cccggtgaag
    19381 ggccgcctgc gccactacat gaacccgtcg aacttcggta tcgccgtcat cctgctgctg
    19441 ttcccctggg ccagcatcgc cccgccgtac cacttcaccg agaacgtcga cacctggatc
    19501 gactggctgg tgcccgggat catcatcgtc ggcggcacga tgctgaacgg caagctcacc
    19561 ggccgcatgc cgctgatcgc cggctgggtg ggcgcgttcg ccctgcaggc gatcctgcgc
    19621 ggcgtcttct tcggcacctc gatcccggcc gcgctcgcca tgatgaccgg cgtcgccttc
    19681 atcctgttca ccaactacat gatcaccgac ccgggcacga cgccgtcgaa gcccggctcg
    19741 cagatcgcct tcggcgccgg cgtcgccctg ctgtacggcc tgctcaccgc cgtccacatc
    19801 tcgtacgccc tgttcttcgc caccgccggc gtctgcgcga tccggggcgg cttcttctgg
    19861 gcgctgcact tcgtgaacaa ggcccgccag caggcgcagg ccccggcgca ggcccaggcg
    19921 ccgtccatcc cgtcccagac gccggccccg gtcatcgtga ccggccccgt ctcggtcaac
    19981 ggcaaagagg cggcgtccgt atgagcacga ccaggatcgc catcgtcggc atggcctgcc
    20041 gatatcccga cgccgcctca ccgcgggagc tgtgggagaa cgcgctggcc ggccggcgcg
    20101 ccttccgcag gctcccggac gagcggatgc gcctggagga ctactgggac cccgatccgt
    20161 cggtgcccga ccggttctac gcccgcaccg ccgccgtcat cgagggctac gagttcgacc
    20221 gggtcggtta ccggatcgcc ggcagcacgt accgctcgac cgacctgacg cactggctcg
    20281 ccctcgacat ggcgggccgt gcgctggccg acgcgggctt ccccgaaggg gaggggctgc
    20341 cgcgcgagcg caccggagtc gtcgtcggca acaccctgac cggcgagttc acccgcgcca
    20401 acatcctgcg cctgcgctgg ccgtacgtcc gccgcacggt cgcggcgacg ctgaaggacc
    20461 agggctggga cgacgaacgg ctggccgcct tcctcgcgga cctggaggcc acctacaaga
    20521 gcccgttccc cgaggtcgac gaggacaccc tcgcgggcgg cctgtcgaac accatcgccg
    20581 ggcgcatctg caaccacttc gacctcaacg gcggcggcta caccgtggac ggcgcctgct
    20641 cctcctcgct gctgtcggtg acgacggcgt gcaaggcgct gctcgacggc gacctggacg
    20701 tcgccgtcgc cggcggggtc gacctgtcca tcgacccctt cgagatcatc ggcttcgcga
    20761 agaccggcgc gctggccaag ggcgagatgc gcctgtacga caagcactcc aacggcttct
    20821 ggccgggcga gggctgcggg atggtcgtgc tgatgcgcga gtccgacgcc gtcgaggccg
    20881 gtcgccggat ctacgccgtc atcgcgggct ggggcgtctc ctccgacggc cggggcggca
    20941 tgaccaggcc cgaggtgagc ggctaccggc tcgcgctgag ccgggcctac gatcgggccg
    21001 ggttcggcat cgagacggtc ggcctgttcg agggccacgg caccggcacc gcggtgggcg
    21061 acgcgaccga gctcaccgcg ctgtcggagg ccaggaccga cgcggccgcg gcgacggcgc
    21121 ccgccgccgt cacctcgatc aaggggatga tcgggcacgc caaggccgcg gccggggtgg
    21181 ccggactgat caagaccgcg atggcggtcc acgagcaggt cctgccgccc gccatcggct
    21241 gcgtcgagcc gcaccagatc ctcgcgaagc aggacgcccc gctgcgcgcg ctgcgcaagg
    21301 cggagccctg gcccgaggac gtcccggtca gggccggcgt cacggccatg ggcttcggcg
    21361 gcatcaacac ccacgtcgtg ctggagaaga gcgggccgcg gcggcgcgtg ctgcccgccc
    21421 gcaccaggag cctggcctcc tccctgcagg acgccgagct gctgctggcc gacgccgcct
    21481 cgccgcaggc gctgcgggag cgggtggcca cgctggccga cttcgtgacc cggctgtcgt
    21541 acgcgcagct cgccgacctg gcggtcaccc tgcagcgcga gctgcgggac cagccctacc
    21601 gggcggcggt ggtggtctcc tcacccgagg acgccgagcg gcagctgcgg cgggtgctca
    21661 ccgccctcga cggcggcgag accagcctgt tcgcctccga cggccgggcc ttcctcggcc
    21721 acgccgacgg cccctgccgg atcggcttcc tcttccccgg gcagggctcg gggcgcggca
    21781 ccagcggcgg ggccctgcgc cgccgcttcc ccgaggtcga ggagatctac gccagggcgg
    21841 cgctgccgtc ctcgggggac atggtggcaa ccgcggtcgc ccagccgcgc atcgtcaccg
    21901 gctcgatggc gggactgcgc gcgctgtccc tcctcggcct ggaggccgac gtcgcggtgg
    21961 gccacagcct cggcgagctg tcggcgctgc agtgggccgg cgccatggac gaggacacgc
    22021 tgctcggcct ggccgccgcc cgcggccggg ccatgaccga gcacagctcc tcgggcacca
    22081 tggccggcat ccgggcgacc ccgcagacgg tgaccgacct catcgccggg ctgccggtgg
    22141 tgatcgccgg gtacaacggc ccgagccaga ccgtcgtcgc cggcccggcc gacgcggtgg
    22201 aggaggcggg gcgcagggcc tccgacgcgg gcctgaactg gaccccgctc gcggtgtccc
    22261 acgccttcca ttcgccgctg gtggcgcccg cggccgaggc gttcggcgcg tacctggccg
    22321 ggcaggagtt cggcccggtc gggcggcgga tcgtctccac cgtgaccggc gaggacctgc
    22381 cgccggtcgc ggacctgcgc gagctgctgc ggcggcagat caccgagccg gtgcggttca
    22441 cccaggcggt cgagcgggcg gccaaggacg tcgccctgtt cgtcgaggtc ggcccgggcc
    22501 gggtgctgac cggtctggcc gcggcggcga cggaggtgcc cgcggtcgcg ctcgacaccg
    22561 acgacgagtc gctggccggg ctgctgcggg tggccggcgc ggcctacgtg accggcgtcc
    22621 ccgtcctcct ggaggacctc ttccacggcc ggctggtccg gcccctggag atcggcgcgg
    22681 agttcagctt cttcgccagc ccggcggagg ccgcgccccg ggtcaccgtg gcggcgacgc
    22741 gggcgcgcgc ggccggggag gccgcgccgc ccgccgcgac ggcggccccc gtcgtctccg
    22801 ccgacgccgc ggccgaggcc ggatcgagca tcgacctgct gcggcgcctc gcggccgagc
    22861 gggcggaact gccgctggag atggtgagcg aggacagcag gccgctcgac gagctgcacc
    22921 tcagctcggt cacggtcatg cacatcatcg accaggccgt ccagcgcctt ggggtgcccg
    22981 ccgcgcaggc ccccaccaac ctcgccaccg cgagcctgcg tgaactggcc gaggcgctcg
    23041 accggctcac gcgggagccg cagggccggg ccgccgcgcc ggcggccgtg gtggccggcg
    23101 ccgccgactg ggccaggccg ttcgcggtcg acctcgacga ggtgccgctc ccggcgcgga
    23161 ccggccccgg ggacagcggc cggtggcggc tgtacgccgc cgggtcgtcc ccgatcgccg
    23221 agccgctgcg ccgggcgctc gaggagggga acgtcggctc cggggtgctg gtgtgcctgc
    23281 ctccggactg cgccgaggag cacctggagc aggcgctgct gggcgccaag gccgccctgg
    23341 ccggcccgcc cggcacccgg ttcgtcctgg tccagcacga ccggggcgcg gccgggctgg
    23401 ccaagacgct gcacctggag gcgccgcacc tgcgcaccac cgtcgtacac accccggcgg
    23461 tgccggaggc ggtcggccgc gtcgtggccg aggtggcggc gaccaccggc ttcgccgagg
    23521 cgtactacga cgccgacggc gtgcgccggg tgccgacgct gcgcgccctg ccggtacggc
    23581 cggccaccca ggtcccgccg ctcggcgcgg aggacgtcct gctggtgacc ggcggcggca
    23641 agggcatcac cgccgagtgc gccctggcgg tcgccaccga cagcggtgcg aagctggccg
    23701 tgctcggccg ctccgacccg gccggcgacg cggagctcgc cgcgaccctg cggcggatgg
    23761 ccgaggccgg ggtgaccgtg cggtacgcca gggccgacgt gaccgacccc ggtcaggtgc
    23821 gccggggaat cgccgagctg gaggcggagc tggggccggt caccgcggtc ctgcacggcg
    23881 ccggccgcaa cgagcccgcc gggctcgccg gcctcgacgc cgacgccttc ggccggacgt
    23941 tcgcccccaa ggtcggcggg ctgcgcaacg tgctcgacgt ggtggacccc ggcaggctgc
    24001 gcctgctggt caccttcggc agcatcatcg gcagggccgg tctgcacggc gaggcgcact
    24061 acgcgaccgc caacgagtgg ctggccgacc tgaccaggga ggtcgccgac aagcacccgg
    24121 gctgccgcgc catctgcatg gagtggtcgg tctggtcgga cgtcggcatg ggcgagcgcc
    24181 tgtcggtggt cgaggggctg acccgcaagg gcatcgccgc gatcaccccc gagcagggag
    24241 tggagatcat gcgaaggctg gtcgccgatc ccgcctcgcc cgtcgtcgtc gtgatcagcg
    24301 ggcgtacgga ggggatcggc acggtccgca gggacgagcc gccgctgccc ctgctgcgct
    24361 tcgtcgaccg cccgctgatc cgctaccacg gcgtcgagct cgtcaccgag gtcgaggtca
    24421 acgcgggcac cgacctctat ctcgccgacc acctcctcga cggcaacctg ctgttccctg
    24481 ccgtcttcgg gatggaggcc atggcccagg tcgcgtacgc ggccaccggg cggcgggaga
    24541 cgccggcgat cgaggacgcg cggttcctgc ggccgatcgt ggtgccgccg gccggcagca
    24601 cgacgctgcg gatcgccgcg acggtcaccg gcgacgacac ggtcgaggcg gcgatccgca
    24661 gctcggacac cggcttcgag gtggaccact tccgcgcccg gctgcgctac accggcgagc
    24721 ccgcggcgga cgggccgccc ggccaggtcg ccgagggcct gcccccggtg acgctggacc
    24781 cggcccggga gatgtacggc gacctgctgt tccagggcgg ccggttccac cggctgcgcc
    24841 gctaccaccg cgccgccgcc cgccacgtgg acgccgacgt ggccgcgctg gccgacgggg
    24901 actggttcgc ccgctacctg ccggacaccc tgctcctcgg cgacccgggc acgcgggacg
    24961 cgctgatgca cggcaaccag gtctgcgtgc cggacgccac gctgctcccg gtggggatcg
    25021 aacgggtgcg tcccggcggc cccgccctcg cggaggcggg cgcgctgcgt tactgcgcga
    25081 cggagcgcga gcgcgacggc gacacctacg tctacgacat cgcggtccga accggggacg
    25141 gcaccgtcgt ggagcggtgg gacggcctga ccctgcaggc cgtacgcaag aaggacggcg
    25201 gcgcgggccc ctgggtggcc cccctgctcg gctcctacct ggagcggacg ctggaggacc
    25261 tgaccggtga ccgggtggcc gtcgtggtcg aacccggcct gccgggcgag ccggacggtg
    25321 ccgccgggcg cggcgcccgc gcggccgtgg ggctgggccg ggcgctcggc cgccccgtcg
    25381 aggtgcggtc cggtcccggc ggcgagccgg agatcggcgg cgaggccggc gacggcgtcg
    25441 cggtgtcggc ggcacacggg gccggagtga cgctgtgcgt cgccggcggc gggccgctgg
    25501 gctgcgagat cgccgaggtg accgcgtccg gcgaggggga cgggcggtgg cgggaggccc
    25561 tcgggccgaa cgccgcggtc gccgagcggg tagccgccct caccggcgag gcccccgcgg
    25621 tcgcggccgc gcgggtcctg gccggggtgc ggtccctgcg acgggccggc ctgccggagg
    25681 acaccccgct cgcggccggg accgtgtccg gctcgtgggc ggtcgtcgac gccggggacg
    25741 cgcggatcgc gacgctcgtc acctccctgc gggacgtcgc ggggccggta gtgatcgcgg
    25801 tgctcaccga agggcggtcg cgggcgtgag tgactactac gaatacctcc acaccgtggg
    25861 gttcgaggag acgaacatcg tcgggaacgt ctactacgtc aactacctgc ggtggcaggg
    25921 acgttgccgg gagatgttcc tcaaggagcg ggcgccggag gtgctcgccg acctgcagga
    25981 cgacctgaag ctgttcacgc tgaaggtcga ctgcgagttc ttcgccgaga tcaccgcgtt
    26041 cgacgagctg tccatccgga tgcgcctggt cgatctcgcc cagacgcagg tcgagttcag
    26101 cttcgactac gtgcggctca acccgggcga gggcgagacg ctcgtggccc gcggcaggca
    26161 gcgcgtggcc tgcatgcgcg ggccgaacac ccgcaccgcg cccgcccggg ttcccgagcc
    26221 gctggtcagg gcgctcgaac cgtacgcgtc ctaaccccag gaggtcagcg tgactgtcga
    26281 ccaatcaacg gcatcatccc tgcagatgga cggccaggtg aacgacgcca aggcgctgcg
    26341 gcgggcgttc ggcgccttcg ccaccggtgt gaccgtggtg acgacgggcg ggtccgtccc
    26401 gcacgccatg accgccaact ccttcgcctc cgtctcgctc gacccgccgc tcgtgctggt
    26461 ctgcatcgac cgggccgccg tcatgcacca gtgcctcagc atgacgggct tcttcggggt
    26521 ctcggtcctc gcggcccacc aggagagcga ggcgaggcac ttcgccaacc gctaccgcgc
    26581 gctgggcgcc gcccagttcg aggaggtcga gtggctgccc ggcgacctga ccggggtccc
    26641 gctgatcgcc gggacggtcg ccaggttcga gtgcgagctg tggcgcacct acgacggcgg
    26701 cgaccacacg atcttcctcg gcaaggtgct gtccatggag cagcagaccg accgggaggg
    26761 cctgctggtc taccgcggcc ggttccagga gctcaccgac cggccggggg tgccggcgtg
    26821 agcgcgacga gccgccgcgc cgtcctcgcc ccgccccgga cccgcaaggg cggcgcccag
    26881 gtggcgccgc ccggcccccc ggtgacggcc acgccgcggc tgttcctcca gctcgtccgc
    26941 gaccggctgg ggctgctcac ctcggccacc gcggcgtacg gcgacgccgt acggctgacc
    27001 atcgggccca agagcatcta cctgttcaac cacccggacc acgccaagca cgtgctggcc
    27061 gacaacagcg cggcgtacca caaggggatc ggcctcgccg aggcgaagcg ggtcatcggg
    27121 gacgggctgc tcaccagcga gggcgaggtc tggcgcgccc agcgcaggac ggtccagccg
    27181 atgttccaga acaagcggat cgctcaccag gacgccgtga tcgccggcga ggcggcgcgc
    27241 ctggtggagc ggctgcgggc gcgggtgggc gggccgccgg tcgacctggc gggggagatg
    27301 acgcggctcg ccctcggcgt gctcggccgc accctgctcg gcgccgacct cgaccggttc
    27361 cactcgatcg ggcacgcctt cgagaacatg caggaccagg cgatgttcga gatggtgtcg
    27421 ctgagcatgg tgccgctgtg gctgccgctg cccgggcacc tgcgcttccg ccgcgcccgc
    27481 cgggacctgt accgggtcgc cgaccgcctg gtggcaggcc atccggacgg cggggacgac
    27541 gtcgtgaccc ggctgctcgc ctcgcccgcg ggcgtcgatc cccggcccgc gcggcggcgg
    27601 atgcgcgagg acctggtcac cctgctgctg gccgggcacg agacgacggc gagcacgctg
    27661 tcgtgggcct tccacctgct ggaccggcat ccggaggtgc gcgagcggct gcgcgccgag
    27721 gccgtggagg tcctcggcga ccggcccccg gtgtacgacg acctgcaccg gctcaggtac
    27781 accgccatgg tgatcgagga ggtgatgcgt ctctacccgc ccgtgtgggc gctgacccgg
    27841 gtggcccagc gggacgacga ggtcggcggc taccacgtgc cggccggggc ggacgtcatg
    27901 atcagcccgt acacgctgca ccggcacccc gcgtactgga ccgaccccga gcggttcgat
    27961 cccgagcggt tcgacccgga ccgcgcgcac ggccggccgc ggtacgccta catccccttc
    28021 ggtgccgggc cgcggttctg cgtcggcaac cacctgggca tgatggaggc gacgttcgtc
    28081 ctcgcgatgg tctcccgcga gctgcggctg gcccatgtgc ccggccgtcc cgtggttccc
    28141 gaggcgatgc tgtcgctgcg ggtccgcggc ggcctgccga tgaccgtcca tcgcgcgtag
    28201 ggagcagcgc gcgggggaat cgggttgaaa gcgagcggcc gggcggtgac gcccggccgt
    28261 cttcgcgtga ggagccgcgt gggagccgcg cggatgcggg ccggccgttc agcaggcctg
    28321 cctggcggcg ccgaccggcg acaacaggtc gcgcagggcc agcaggaccg gcgggtcgag
    28381 cgggcgcatc ggccggagcc ggacgtcggc gacctgtgct cccgcgccgg gccgcacggt
    28441 gatcggcccg ctgcacgaga tgcactgcgc ctcgtcctcg ccgccggggg tgccgaaggc
    28501 gtcctcgtgc ccctcggcgg ccgactgcgc gatcaggtgc caccgccccg gcggcacgtt
    28561 ctccagcacg tacggcccgg gccggtcgag cagggtgtag cagaccgggc gtccgccgag
    28621 gatccgctcg gggaacaacc cggcgaagac cggccggtcc ggcagcggcg aggagatctc
    28681 gcccgcgatc gtcgccgtgg cgccggaggg ggtggcgcca ggcccggccg cgagcagctg
    28741 cggcgtcacg cttccgagca cgcggtacct gctcggggac aggcccacgc tgctggtgaa
    28801 ccgcgagctg aaggtgccga cgctcgaata gcccacctgg tggctgatgt tcgtcacgct
    28861 catcacggtc gaggcgagca gcctcttggc ctcgcggagc cgtacggcgg acaggaaacg
    28921 tcccggggac agtccggtga cccgctggaa gacccgcgag aagtggaact tgctgaacat
    28981 ggccacccgg gccatgtcgt cgatggtgat cggttcgccg aggttctcgt gcatgttctc
    29041 gatcaccctc agcgcggctc gctcgattac ttcgtccatt actcctcccg gtgtccggag
    29101 gcgtctggtg agcgatcctg aatcggatcg gcgggtccgc gcgcgaatgg tgccgcccgc
    29161 ggatttcgtg gaatgctcgt cgcccggaat tcacggcggc gccctccgat ttccggccgc
    29221 ctcgttccgg tctttcgttc ttttacatgc ggccggaggg gtccggcgct gcatggaaac
    29281 gggaattaat ttgagaattg tgttcgggtg gtcgtccggt cgctttccgt ggtcgccgcg
    29341 cggcacgccg gcggtgtgcc cgtgctacgc cgcggcgggg aggatctgcc gcggcgccgg
    29401 cggcccggcg tggtggcgtc gctcgcgcgg gtagccgagc gacacctcct cgaaccgcac
    29461 gccgtcgtgc catgtcgtcc gcggcacgtg caggtggccg tacaccacgg cggacgcgtg
    29521 gtagcgcagg tgccagtcgg ccgtgtgctc ggtgccgcac cactgggcga acacctggtg
    29581 ccgcagcact cgggtgggct cgcggagcag cgggaagtgg ttgaccagga cggtcggcag
    29641 gtcggggtcg cgcgcgtcga gccgcgactc ggtctcccgc agccgcgccc ggcaccacgc
    29701 ctcccggctg gggtacgggt gggggtcgag caggatctcg tcggtgcaga cgacgcccag
    29761 ccggtacgcc tgggcgagcg actcctcctt ggtggtgtgc gggtcgcgga agctgtagtc
    29821 gtacagcagg aacaggggga ccacggtcgc cgggccgccc tccccggtcc acaccgggta
    29881 ggggtcctcg ggagtgagca ccccgatccg gcggcagacc tggacgagcc ggcggtagcg
    29941 ctcctcgccc cgcaggggct cggggtcgcc gggcgtggtc cacagttcgt ggttgccggg
    30001 cgtccacaca accgccgcga aacggtcccg cagcgtggcg agcgcccatt cgacgtcgga
    30061 aatccgctcg ccgacgtcgc cggcgacaat cagccagtcg cccggcgcgc cgggacgcag
    30121 cgattccacg agcgcccggt tttccgggtg ggcgacatgg aggtcgctta tcgcgagcag
    30181 tcttccattt ttcgtccgcc ggccggtcac gacgaaatcg taaagggatc cggcgggcgc
    30241 gggaatcgct cgcggcggtt atgggacccc agatttccgg ataggggaca gggggtccgg
    30301 ataggggttg tgacgccagg ttggggcggc caattctggc tccgttggcc caggccgcgg
    30361 gagagcgctt ctcagcccgc gggcagggga cgcggccctg ttggggagtg ggggcggatg
    30421 gccgaggctc gcgacgacgg gttctcgcgc tacgcgagac atgcctggcc ggcgctgcgg
    30481 cgcacggcct tcctgctcac gtcggactgg cacgaggccg aggacctcgt ccagcggacc
    30541 ctgatcgccc tccaccgcca ctgggacagg ctggagcggc acgacaggct ctccggctac
    30601 gcgcgggcga tcatgatccg gctggtctac agcgaccgca ggtcgcaccg gtggtcgcgg
    30661 gaggtcctgc acgagctgcc gcccgagccc gaacccctgg ccgaccccta cacgctcgtg
    30721 gtcgaccgca tcctgctgat gaacgcgctc gccggtctcg gcccccggca gcgggccgcc
    30781 gtcgtcctgc gctactggga ggaccgcagc gtcgaggaga cggcgtcggc gatgggcagc
    30841 gagggctcca cggtccgcag ccagacggtc cgcgcgctgg ccaccctgcg tacggcactg
    30901 acggccgcct cggacggcac ggccggagag gcgcggcgca acgcggaaga tgcgacgcgc
    30961 gcggcggtgc ccggacgatg aaggtgacct gagtcgaact gagacacgag ggaacgccca
    31021 tgccgccgcg agccccagca gacgacaatc ccaggacgac gacactggaa gccttcgcgg
    31081 acacgatcgt ccccggtgag aagaggtacc ccggcgacct ggccgtggcc ggcgcggccg
    31141 agggcgccgg ggcggtgcag gccggcgcca tcgagctgct cgaatggaac gcgaccggcg
    31201 tcacggaggg cctggacgac tacgcccgcc tgctcggcga ccacgcccgc gactacgcgg
    31261 cggagcacgg gctcacgctg gacgactcgt tgccgccgtt cgtcgccctc accttcgagc
    31321 accggaccgc cctggtgcgc cggctgaccg cgcccgacca cccggagaag gcgttctggg
    31381 tcctgctcgc gctgttcagc aacatggcct acgactccgc ggcgcacacg agcacggccg
    31441 aggcgatcgc cgccgggcat cccgggctgc tcgcgatggg catcgcccgt cccggcgacg
    31501 acggactgtg gcggttcccc gcccactcct acggcaggcc cctggcccgc ctgcacccgg
    31561 acacgacccc ctcagggagc cccgcatgac cagcactgaa cgcaccgacg tcctcgtggt
    31621 cggcagcggc ttcggcggcg ccatcgcggc ctaccacctg gccgcgggcg gggcgcgcgt
    31681 cgtcgtgctc gaacgggggc cgtggctggg cgcgcaggac ttcgagcacg acttcaagct
    31741 cggctcgtcc tacacgcggg ccttcgactt cgtcgtcggc gacggcatga gcgtgctcgg
    31801 cggcaactgc gtgggcggcg gaagcgtcgt ctacttcgcc gccatgcccc gcgcgccgcg
    31861 cttcgtcttc gagcgccacg gaaccatcgg ccgccggatg tggccggcct ccgtcagccg
    31921 cgacaccctc gacccctggt acgaccgggt ggcggagtcc atccccgtca ccacccagga
    31981 ctggaacgac gtcacctacg cgggcgggct gtgggccgcc gcctgtgacc actccggccg
    32041 caccgccaac ccggtgccgg tggcgatcga caacgccaag tgcgtcaact gcaactggat
    32101 gatggccggg tgccgcttcg acgcgaagcg ctcgctgctg accaactacc tgccggcggc
    32161 gctcgcccac ggcgcgcaga tccgcccgct gcacgaggtg cagcggatcg agcgcaacca
    32221 cgacggctcc taccgcgtgc actacgacct catcgacgag gaggactacc ggatccgcta
    32281 cgacggcggg gcgatcgacg ccaagatcat cgtgctggcg gcgggagccg gcgccacgcc
    32341 cgtcatcctg cagcgcagcg aggcgacgct cggcgccatg ccgcacgcgg tgggccgcta
    32401 cttctccggc aacggcgagc ggctcaacac cgcggtgctc aacgaggacc gggtgcgcga
    32461 cgtgctcggc ctgtcccggg gcgacggcct cgcgtacgcg gccaaccaga tcggcaaggg
    32521 cccgaccgtg gcgaactggg accggctcga cggctcgctg cccgagttca cccgctactc
    32581 gctggagcag ctctacttcc cgcccggcct cggcaccatc ctcgcgcagg tcgccgacgc
    32641 cgccccgggt gagtcgacct ggttcggcgt gaagaagaag gagatgctgc ggcgctggca
    32701 gtcctggctg atcatcttcc agatgatcga ggacgccaac gagggcgtct tcggcccgcc
    32761 gccggccaag ggcaacgccg accgggtgtc ccagcagatg ctcggcgtcg ggcgcctcaa
    32821 gtacgacccc gcggagacca cgctgcgcgc ctgggccatg gcggacgccg aggtcaagga
    32881 gatcctggag cgcgacggcc tggccaccgt caccgcctgg accaacgaag tgatcggcgc
    32941 gtacaccgtg cacccgctgt cgtcctgccg catcggcgac gaccccgcga cctccgccct
    33001 cgacgaccgg aacgagctgc gcgggcaccc gggcatcttc gtcaccgacg gctccgccgt
    33061 gccgggcgcg ctgaccgtca acccggccat gaccatcgcg gcgctcgccg agcgcgcgat
    33121 cccgggcatc gtccgggccg cgcaggaccg gggcgtggac gtcacctacg gcgcgccggc
    33181 ccccgacggc gggaccagcg gccgccgcgg ggtcgccgac ctgctgccga gcctgacgag
    33241 aaggtaaggg ggagccgaga tgggggccgt cctcgcccgc gccacgctgc cgggcacgct
    33301 ggcgcaggtc cgccacgtcg ccccggtgcg cccgaacgcg gcgccggacc tcgtccgccg
    33361 ggtgtacgcg caggtcgagc gggacttcgg catgctggcg ccgcccgtga tcctgcactc
    33421 gcccgccccg cccgtcctgg ccgcgtgctg gctggcgctg cgtgagtcgc tgctcgcgcg
    33481 gggcgcggtc gcccggcagg tcaaggaggc cgtcgcgacg gccgtctcgc ggggcaactc
    33541 ctgcccgtac tgcgtggacg tgcaccgggc cacgctggac gccctcgtca gacgtggcgg
    33601 cgcggccgcc gacccccgga cctcgcggat cgaggagtgg gcgcgggcgg ccgcgcggcg
    33661 cggggaggcc gcctcgcacg ccctcccggt gccgccggac caggccgccg agctgatcgc
    33721 ggtggccgtg acgttccagt acctgaaccg gatggtcaac gtcttcctcg gcgactcccc
    33781 gctgcccccc ggagtgcccg tacgggcccg caagggactc atgcggctgt tcgggctgct
    33841 cattgccccg gcggcgagca gggcggcgac cccgggcgac tcgctgagcc tgctgccgga
    33901 cgcgccgctg ccgcccgacc tgtcctgggc gcgggacgtt ccgcacgtcg ccggggcatt
    33961 cgcccgggct gcggcggccg tggaggtggc cgggcgccgc tcggtgccgg aaccggtgcg
    34021 cgacctggtc acggacgtgc tcgacggctg gaacggcgag cctcccggcc tgggccgcgc
    34081 gtgggtcgcc ggcgccgtgt ccgtcctgcc cgaccggcac cgaccggccg gacgcctggc
    34141 gctgctcacc gccctcgcct cctaccaggt ggacgagggg gtcgtggacg aattcaggcg
    34201 cgcggagccg gacgaccgga cgctcgtcga actgacggcg tgggccgcca tgtccgccgc
    34261 gcgccgcgcc ggcgcctggg cccacgaggc ccgcccgcat gttggtgacc gtgacaccgc
    34321 gacgacttct agtgagagga ctgcccgatg acccagctgg agaccgtgct cagggacctc
    34381 accgcggagg gcgagcagct cgaccgcatc gtggccggcc tcgacccgga ccagtggaac
    34441 ctgcccaccc ccgcgcccgg atggacggtc agggaccaga tcgcccacct caccttcgtc
    34501 ttccggctgg ccgcgacggc ggcgagcgac cccgcggcgt tcgaggcgat gaccgccccg
    34561 gccaagggga acttcgacgc ggcggtgaac gccgcgctca agatgttcga gaacgacacg
    34621 ccggccgaac tgctcgccaa gtggcggtcg gtacgcgcgg aggtggtcga ggccctaccc
    34681 gccgtgcccg cggacgcgac cgtgccctgg ctggtcaacc cgctgccgcc ggtcgtgctc
    34741 gcgtgcgccg ggatcatgga gcagttcgcc cacgggcagg acatcgccga cacgctggga
    34801 gtggaactcg agcgcaccga ccgcctgggc cacctcgtcg tgttcgccgt gctcacccgc
    34861 gacttcggct acctgtcgcg cggcctcacg ccgccggccg agcagttccg cttcgagatc
    34921 accgcgccct ccggccaggt gtgggcgtac gggcccgagg acgccgagca gcgggtctcc
    34981 ggccccgccg ccgacttctg cctgctggtg acccggcgcc ggcaccggga cgacctcgcg
    35041 gtcacggccg tcggcgccga ggccgaccgc tggctggaca tcgcccaggc ctaccgcggc
    35101 ccggccggac agggccgcag gccgggccag ttcgctcccg cgcgcgtgta gcgggaggcg
    35161 gagtaaggag gaaccgatga ggcccacacc cgcgggcttc cggacggcgg gggagacgcc
    35221 ggggacggcg ggagaggtgg ccggctgcct ggacggcacg gtccacctcg cgtacgcgcg
    35281 ggcgtcggcg gccgatcctc cggtggtcgc cgccggtttc tccgccgagg cggcactgtc
    35341 cagggcacgg gcccgcgccc gggccctggg cctgctgcgt gaaggacccg caccgcgggc
    35401 gacgcccggc gggggcggca gggcactgcg cctgtccgat ttcgtgccgc accccatcgc
    35461 gccgcagctc atcgcgccgc acgccgccgc gccgcacgcc gccgtgccgc acgccaccgt
    35521 gccgcacccc accgggagcg gcggcccgct cgtcgcgggc agggggctgc tgaccggtgc
    35581 cggttaccgg ctgccgggcg aggtcgtgtg gctgcgggag cacggtggcc cggtcgagcc
    35641 caccgcgatc ggcgtggtgg acgactgcgc ccccgccggc gtcgccgacg tgctcgccca
    35701 cgacgcggtc ctccggtggc gggccgcgtc ccgccgcccg ccgctgcgga tcacgccgta
    35761 cctcggcgga ctgctgccac ccggggtcgc ggaggcggcc tccgggctcg gcctgtcgat
    35821 ctcggcgtac gtgctgccgg ccggcgaggt caggaccgtg ctcgtacgcg tgcgcggcgc
    35881 ggccacgacc acggccgccg cctgcgggcg cacgctcggt gcggcggtgc gcgaggcttt
    35941 cctgctcgcg gtcgcggccg gggcgcagcc ggggcaggcc gtcccggacc tgggcgcgcc
    36001 gagccgcctc gtcgcgtggc gccacgagga cggtcacccg gcggacctgg agcgcacggc
    36061 cgtcgacgcc gatcccggga tcgtcgacga gcccgccggg cccgtcccgt ccggctgggc
    36121 gggcgtcgcc taccgccggt tcgggcacga gccgatcctc gtcgaggcgg gggagtcccg
    36181 cgaggccgtc aaggtggtct gcccgggcgc ctcctgctac cggcgagagc ggccggggat
    36241 cgaggtgccg tgtccggttc gctagtcccc gccccgtcgc acaccccgtc gcgcggatcg
    36301 caccacgaag acgcgggagg tgagccgtgg acgtctccgt gatcggcatc tcacccgagg
    36361 cggccgagat ctaccggtat ttcctccggt gcaagggcga gggagtcggt tcggtgccgg
    36421 aggcgctggg cctgtccgcg gacaccgtcg aggctgccgt ggagacgctc agccggctgt
    36481 ccctgctcga catcgccgac cggcacaggg tcgtggcgac ggagccgcgc atcggcatcg
    36541 agcggctggt ggaaaagcgc ctcaacgagc tcaacgccga gatccggcgg gtcctggcgg
    36601 cgcgcgacgc gatcgccgtc ttcatggagg acaagcacga gggcgaccgc gcggcgacgg
    36661 tcctcgacat cgaacgggtg gaaggcgtcg agcgggttcg ccagcgcatc gacgacctcg
    36721 ccttcttctc ctacaaggag acgctctgcc tgcatccggg cggcccgttc agccgggtga
    36781 tgatcgagtc ggcgctgccg ctggacaccc gctcgctgcg ccggggcctg gcgatcaagg
    36841 gcgtctacca cccggccgcg ctcgacgacc cgttcatggt gtcctacctg cgcgagctgg
    36901 tcagcctcgg cgccgaggtg cgcgtcaccg atcagccgat ggaccgcatg ctcatctacg
    36961 accggagcgc cgccgtcgtg cccatcgacc ccaaggagag cgcgaagggc gcgttgctgg
    37021 tcagggagcc cgggctggtc tcccagctcg tcatctactt cgacggggtg tggaagtcgg
    37081 ccaccgactt ccgcgacatc atggagccca cgaccatgga gcccgcgctg tcggagatgg
    37141 agcagcgggt gctcgcggtg atggccacgg cggacaagga cgagatcgcg gccagggagc
    37201 tggacgtctc ggtgcggacc taccggcgct acgtggccga tctgatggcc aggctcggcg
    37261 ccgtcaaccg gttccaggcg gccctgcggg ccaaggagga gaactggatc tgagctcggt
    37321 gcggggccca cgcgggggcg cggcgctcac ccccacgtgt tgccgtactg caccgggctg
    37381 ccccaggtgt tcccgtcgtt gccgtcggcg agcacggtga tccgcggccc gtcgtccgcg
    37441 acgcctgcgc ctcccgccgt gctcgccatg ccggccgtgc ccgccgcgag cccgcacgcg
    37501 agggcgccgg acgccagggc gatggcccac ttgagggtgc tccacgaagc ggtgggggag
    37561 gagaccaggg tcttcatctc ggtgccttct ctcgctgccg gaggggttgt tctcgcacta
    37621 cctactgtgc ggcgccacag gacccggaac caggcgtccg gcgtgcagca agctgcaccg
    37681 gcgttaccgc ttcctgccat cccggcgccg catggcaaag gaggaggtga cagcgcgggc
    37741 ccgcgagatt ttgactgagg ccacgtgacc cggaacgccg gcgcgcgcac aacgcgcacc
    37801 gcgggggaag gaacgctgat gagcatctcg gaactcgacg tcgcaccggc ggacctgccg
    37861 ccgcggacgc ccccggagcg gccggcccgt tcgatgggcg cgctgcgcga ggagctggcg
    37921 cggctgcgcg cccggaccgt cgccggccgt cccgacggcg tggcccggca gcacgcgctg
    37981 ggcaagcgga ccgcccgcga gcggctggac ctgctgctcg acgagggctc gttcgtggag
    38041 atcgacatct accggcggca ccgggcgcag gggctgggca tggacgggcg gcgcccgcac
    38101 accgacggcg tcgtcgccgg ctccggcacc gtccacggcc ggcgggtgtt cgtctacgcc
    38161 caggacttca cggtcttcgg cggctccctg ggggaggcgc acgccgagaa gatccacaaa
    38221 gtgatggacc tcgccatgtc caccggctcg ccgttcatcg gcctgaacga cagcggcggc
    38281 gcgcggatcc aggagggggt gatgtccctc aacggctacg gcggcatctt ccggcgcaac
    38341 gtccaggcgt ccggcgtgat cccgcagatc agcgtcgtgc tcgggccctg cgccggaggc
    38401 gcggcctact ccgccgcgct ggccgacttc accttcatgg tgcagggcac ctcgcagctc
    38461 tacctgaccg ggccggacgt cgtcgaggcg gtgaccggcc agcgggtcac ccacgccgag
    38521 ctgggcggcg cccaggtcca cggcacccgc tcgggcgtgg cggcgttcgt gcacgacgac
    38581 gaggaggcct gcctggcgga ggtgcgctac ctcctctcga tgctgccggg caacaacctc
    38641 gaaccgccgc ccgcggcgcc gccgtgcgac gcgtcccgcg acacgcgccc gcgcctggcg
    38701 gagatcgttc cggccgagcc cagcaagccg tacgacatgc gcgaggtgat cgcggagctg
    38761 gtcgacgacg gcgacttcct cgaactgcac gagggctggg cgcgcaacgt gatctgcgcg
    38821 ctggcccgcg tcgacggcgc ggtggtcgga gtggtcggga accagcccct ggtgctcgcg
    38881 ggcgtgctgg acgccgacgc ggcgcagaag gcggccaggt tcgtgcggtt ctgcgacgcc
    38941 ttcaacatcc cgctggtgac cctcgtcgac gtgccgggct tcctccccgg caccgaccag
    39001 gagtacgccg gcatcatccg gcacggcgcc aaactgctct acgcgtactg cgaggcgacc
    39061 gtgccccgca tccaggtcat cctccgcaag gcgtacggcg gggcctacat cgtgatggac
    39121 tcccggtcga tcggcgcgga cctgtcgctt gcgtggccga ccaacgagat cgcggtgatg
    39181 ggcgccgagg gcgcggtcaa cgtcgtcttc cgccgtgagc tcgccgccgc ggccgacccc
    39241 gcgggcctgc gcgcggagct gctcgcccgg tacgccggtg agctggtcca cccgcagtac
    39301 gcagccgagc gcggcctggt cgacgacgtg atcgacccgg tgcagacgcg ctccgccgtc
    39361 gcccgcggcc tcgccatgct gcgcgacaag cgcaagccgg gggcgcagcg caagcacggg
    39421 aacgtgcccc tgtaagcgtc ccaccctcgc gactgcccat ccccacgccc gcctcagcct
    39481 cgcgcctgcc cctacccctc gcgtccgccc agcctcgcgc ccgccccgcc cgtctgtggc
    39541 ggcggcgggc gttcgcgtgc ccggacgcct ccgctggcag gatgcggtaa ccccgctgca
    39601 gcttgctgcc tgggcaagcc ctggttccac gccccccacg gccgcacatt gaaggtgtga
    39661 cgacaacagg cagcggacgg aggcggtggc ccgcgggcgc ccgcctcccc ggaggagccg
    39721 cgtgcggggc ccggccgccg cggcgcgcga ggccgccagg ccggcggccg gagagggagc
    39781 cgaggccatg ctggttcagc tgacgatgcg ccggacggac gggcaggcgg ctccgggctc
    39841 gccggtggac gggatccggg tgctcgcgct tctccccggg agctggcaca agcacctcga
    39901 acaggtcgcc ggcgacatcg tcatcagaat ccgcgcggaa gggacgacgg cgggaggagt
    39961 ccgcgccgag gtggcgagga tcctcaccag ccccgaggtc agccacctcg aactggtcgc
    40021 ctgccgtccc ctggagggtc cccggcagta ggacgctaac gaaggagacg aaccgatgat
    40081 cgcctcggtt gtggcggcgg gtgagtgcca tgtgtggtgg gcggacccgc ggctggaaac
    40141 gatcgacacc ctggtgcggg acctcagcgc gaacgagttg cgccgtgcgg cccgcttccg
    40201 ccgcgagccc gaccgccgcc gcttcctgac cggggcgcgc ctgctgcggg aggccgcggc
    40261 cgagcggctg ggcgtccgtc ccgcggacgt ggtggtggac cggacgtgcc ccgactgcga
    40321 caggtaccac ggcaagcccc gcatcctgac ggagggggag accctgcacg tctccatctc
    40381 ccattcgggt gaccgggtcg cggtggcgct gacggccgtg gggccgctgg gcgtcgacgt
    40441 ggaggcggtg ccagcgacgc cggtggacga cctcgcgcgc tgcgcgctga ccgagaccga
    40501 gcgccgcgcc ctcgtggccc ttcccgagca cgcgcggtac gaaggcttcg cccggatctg
    40561 ggtgcgcaag gaggccgcgc tcaaggccac cgggcacggt ctgcgaatct ccccggaccg
    40621 ggtcgaggtg accggcccgg gggagagccc cgcgctgctg agctggccgc tggacgtgcc
    40681 gcccgcagcg gtgcggatcc accccctcga ccccggcccc gggtacgtcg ccgtcgtcgc
    40741 ggtgctcggc ggcgaccacg gcatcacggt ccgcgaggcg gacgccgcgc tcctgcgccg
    40801 gcgcgccggc ttcgagacgg cacgccaggc cgcgtgagcg gcgttgacga cgcccggtgc
    40861 gaggccgctc aatggcgggt gaagaccagc tcgccgcgtg aatccgcacc gggccgacca
    40921 gaagaaggct gattctcgtg aacaagggct tcatcctgat cccgggcccc tggatgggcg
    40981 cctgggcgtg ggggccggtg gcgcggcgcc tgcgcggcta cggtcatgcc gcccgcgcga
    41041 tcacgctccc cggcctggcc gatcccgacg gggacgtcgc gggcgtcggc ctggagacgc
    41101 acgtcggcac cgtgctgtcg ctgctggagg aggaggacct gcgcgacgtc gtcctcgtgg
    41161 cgcacagcta ctccggcatc gtggccggcc aggtcgccga ccgcgcggcc gaccgggtgg
    41221 cgcacaccgt gttcgtcgag gcgttcctgc cgcacgacgg caagtcgatg ctgcacgcgt
    41281 tccccgagcg ccagcacgcc gcggagctgc ggctcatcga ggacaacggc ggccgctggc
    41341 ccgcgcccga cgccgccgtc gtgggcgagg ggcagggcct gacccggcgg caggcgcggt
    41401 ggctggccga gcgcctcgtc ggccatcccg gccgcaccat cgccgagccc gccgtcctga
    41461 cccgccccct gacgcagcag cgcgccacgt acgtcgtctg ctccatggaa cacttcggcg
    41521 gacgcgtcgc cgccgacgtc gacgccctgc gcgccgcccc gaactggcgc ttccacacgt
    41581 tgccgaccgg gcactggccc atgatctcgg cgcccgggcg gctcgccctg ctcctgcacc
    41641 ggatcgccgg gcgcgcctag tagggggcgg cccggcgcgc cgccccggta atcgcccgca
    41701 tccggggtaa cttcggcatc atggccaccc gtacgtccgg acaggggtcc ggcaagcgcc
    41761 ccgcgtcgcg ctccggatcc cgtacggctt cccctaagcg atccccggcg ggttcccgag
    41821 gcagggcggc gcccaggccc gcgcccaagc ggccggtcgc gaccggccag gatccggtca
    41881 gctggttctt cctcatcatc ggcaagatct tcatcagcat gtggatgctg gtggcgaacg
    41941 gcgtgggcaa ggcggcgcgg gggctcggcc agggcgcccg cgacctcgat cccgtgcacc
    42001 gccgcgacgg gcagggcctg tcggtgctcg cgggcgccat cgtgctcgcc gccctgacct
    42061 ggagggacac caagacgggt ttcgccgcgt tcgtcgacgc cgtggtgcgc gggacggtgg
    42121 gggcgctcgc ctggggggtg cccgtgctgc tcgcgctgct cgcctggcgg ctgctgcgcc
    42181 accccgacca gaacgccgag accggcagga tgggcatcgg ctggacggcg ctgctggccg
    42241 ggatcctcgg aatcgtgcac gtcgcccacg gcacgccgta cccctcgggc gggcccgacg
    42301 acggcatgga caacgtgtcg gcggcgggcg gcatgatcgg tttcatcgtg tcggctccgc
    42361 cgtcgagcat cctgccggcg ttcatcacga tcccgctgct gctgatgctg tccggcttcg
    42421 gcctgctggt gatcaccgcg acgccggtcc accgcatccc cgagcgcctc gccgagatcc
    42481 agcacatgct cttccagcgg ccggacgaga ccggggagcc ccgcaagagc ccggcgccgt
    42541 ccaggaagcg cacgcgcaag cagcagggcg gcgggcgcga cgccgccgag ggcggcgacg
    42601 gcgtcaagcc gtacgacacg cccgtgctgt cggagaagga ccacgcgccg gagatcgtcc
    42661 ccggtctggt ggacgaggca gtggagtcgg ccgagccgac cgagccggag atgcggctcc
    42721 ccaagacggc gccgcagcct ccgctgccga cgcccgcgcc gcgcaaggtg gagcagctcg
    42781 tcctgtccag ccaggagggg ccgtacacgc tgccggacgt tgcgatgttg cggccgggca
    42841 gcgcgccgaa gcaggagacc aaggccaacc ggacggtcgt gaacgcgctt accagcgtgc
    42901 tggagcagtt cgccatcgac gcgcaggtcg tcgggttcac ccggggcccg acggtgaccc
    42961 ggtacgagat cgagctgggc ccggccgtca aggtcgagaa ggtcaccgcg ctcaccaaga
    43021 acatcgccta cgccgtcaag tcggcggacg tgcggatcct gtccccgatc cccggcaaat
    43081 cggcgatcgg cgtggagatc cccaacgtcg acaaggacct cgtgtcgctc ggcgacgtgc
    43141 tgcgctcgca ggtggcccag gccgaccacc acccgatgat cgtcgggctc ggcaaggacg
    43201 tcgagggccg caccatcgtg gccaacctgg ccaagatgcc gcacatcctc atcgcgggcg
    43261 ccaccggcgc gggcaagtcg acgtgcatca acgggctgat ctcctcgatc ctgctgcggg
    43321 ccacgcccga cgaggtccgc atggtgctgg tcgaccccaa acgggtggag ctcagcgcgt
    43381 acgagggcat cccccacctc atcacgccca tcatcaccaa cccgaagaag gccgccgagg
    43441 ccctcgaatg ggtggtgggc gagatggacc ggaggtacga cgacctcgcg gccagcggct
    43501 tccggcacgt cgacgacttc aacaaggccg tgcgcgcggg caagctggtg ccgccgccgg
    43561 gcagcgagcg cgtctaccag ccgtacccct acctgctggt gatcgtggac gagctggccg
    43621 acctgatgat ggtcgcgccg cgcgacgtgg aggactcgat cgtccgcatc acacagctcg
    43681 cccgggccgc cggcatccac ctggtcatcg ccacccagcg gccgtccgtg gacgtcgtca
    43741 ccggcctgat caaggcgaac gtgccctcgc ggctggcgtt cgcgacctcc tcgctcgccg
    43801 actcgcgggt catcctcgac cagcccggag ccgagaagct cgtcgggcag ggcgacgcgc
    43861 tgttcctgcc gatgggcgcg agcaagccga tgcggctgca gaacgccttc atctccgaga
    43921 aggagatcgc ggaggtcgtc ggccactgca aggcccagat gcaggccgag taccgggagg
    43981 acgtcgccgc gcccgccacc gcgaagcggg agatcgacga ggagatcggc gacgacctcg
    44041 acctgctggt ccaggcggcc gagctgatcg tgtcgaccca gttcggctcc acgtccatgc
    44101 tccagcgcaa gctgcgggtc ggcttcgcca aggccggccg cctgatggac ctgctggaga
    44161 gccgcaacgt ggtcggtccg agcgaggggt ccaaggccag ggaggtgctg gtcaagcccg
    44221 acgagctgcc cggcctgctc gccgatctgc gcggggagtc gtagggccgc cgcccgtcgt
    44281 caggccgatc cggccgccgg cgcgggggca ggcaggcgcg ccacgccctc gtaccgctgc
    44341 ccaatgatcg gcccggcggc gggcccggcg gcgaagaaat ggccgggacc gtcgacgcgc
    44401 tcgcccatgt gggcgtcgac gaccacgggc tcgacctccc ggccggtccg cgcgtccacg
    44461 aggatcatcg accgctcttc cggggccagt cgcgcgttcc gccatgccgc gagcgcgacg
    44521 tacgacaccg ctgtccgcgc gcaccgtgga caacagcgtg gacaccaccg tgcacaccac
    44581 cgtggacaag accgtggccg gtcgtacggt cgtgacgtgc aggctcgagg gcacgttccc
    44641 gggcagtccc gtggacctcg actatcgctt cgacctcgac gacgcggagc ggatctcccg
    44701 tctggagatc gtcgtgtccc gtcccgcccc tgaaaccgct atggaggtga cagggtagtt
    44761 gctcagggtc cacccatggg taccctccgt agtcagttac tgattgaatg tgactaacta
    44821 cgcatcgtgg ggcgagctgg acgacggtgc gcttggagac aggggggcgg aacgatgagc
    44881 gtaggtgctg ttttggccga agcccgtgag cgcgccgggc tgaccgtgcg tcagctcggc
    44941 gagcgcacgc ggatccgcga gaccgtcatc gaacgcttcg agcaggacga cttctcggtg
    45001 ggtgacttct acgcgcgcgg gcacatccgg accatcgcct ccgatctcgg cctggacccg
    45061 gacgaggtcc tgcggcagta cgagcaggag aacgccgacg gcgcgtcgcc ggtcagggcg
    45121 tcggccgtgt tcaggggcga cgtgggcgag cgggcccgcc gggcccccgg ctggacgaag
    45181 gccgccgcgg tcgccctggc catcgtcgtg gtcgtcgtcg tcgcgcggat gctcggaggc
    45241 tccggcgaga aggcgggccc gacggccgcc cagcttccgg tgaccgcgcc gcacgcgcac
    45301 gagaggcagg cgaagggcca cgacaggaag agcctcgagg aggccttcgg gcccggccgc
    45361 gtggtcgtga aggtcaccac gcgcaaaccg gcctacgtcg acgtgaagga cgccaagggc
    45421 aaggagatct tccgggggac gctgccggag gggaagacca cggcctattc ggccaaggac
    45481 aaggtgcgga tgttcatcgg tgacgcgggg gcggtccgcc tggaggtcaa cggaagggac
    45541 ctgggaaccc cgggcaggga cggccagatg atccgccgca ccttcgaggc gggcggcccg
    45601 agtccccgtt aatcgccgac tgccgatacc gtagttcgca tcatgtcttc tcgccgaacc
    45661 gtatcgctga tcacgctggg ctgcgcccgc aacgaggtcg actccgagga gctggccgcg
    45721 cgcctggagg ccgccggctg gcacaccggc gacgacgatc ccgacgtcgt cgtcgtcaac
    45781 acgtgcggct tcatcgattc ggcgaagaag gactcgatcg acaccctgc
//
