LOCUS       NZ_JACJHT010000009     26451 bp    DNA     linear   CON 19-SEP-2024
DEFINITION  Priestia aryabhattai strain S00060 Ga0436288_09, whole genome
            shotgun sequence.
ACCESSION   NZ_JACJHT010000009
VERSION     NZ_JACJHT010000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Priestia aryabhattai
  ORGANISM  Priestia aryabhattai
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Priestia.
REFERENCE   1  (bases 1 to 97683)
  AUTHORS   Carlos-Shanley,C.
  TITLE     Functional genomics of gut bacteria from endangered species of
            beetles
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 97683)
  AUTHORS   Carlos-Shanley,C., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2020) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.14.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 248.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014138775.1-RS_2024_09_19
            Annotation Date                   :: 09/19/2024 05:54:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,314
            CDSs (total)                      :: 6,206
            Genes (coding)                    :: 6,105
            CDSs (with protein)               :: 6,105
            Genes (RNA)                       :: 108
            rRNAs                             :: 8, 5, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 4, 5, 3 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 32 of 103
            Pseudo Genes (incomplete)         :: 62 of 103
            Pseudo Genes (internal stop)      :: 19 of 103
            Pseudo Genes (multiple problems)  :: 12 of 103
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:01:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 16169
            Orig. end                         :: 42620
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JACJHT010000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26451
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26451
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26451
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16451](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16451)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    7..23
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 24.03"
                     /tool="antismash"
     tRNA            580..651
                     /anticodon=(pos:16782..16784,aa:Cys,seq:gca)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="HNP21_RS25560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="HNP21_005355"
                     /product="tRNA-Cys"
     gene            580..651
                     /locus_tag="HNP21_RS25560"
                     /old_locus_tag="HNP21_005355"
     gene            679..2100
                     /locus_tag="HNP21_RS25565"
                     /old_locus_tag="HNP21_005268"
     CDS             679..2100
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016127292.1"
                     /locus_tag="HNP21_RS25565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005268"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_182527910.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.2e-47, bitscore:
                     154.4, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTSMTIITTLLICFCFTNYGHAKTETNQYYTVILKDRSKWTQS
                     IKKIKKSQGEITYTVPEIGLIQFKGNQKVAKTNASLFKSLSPSLKLEKPSTSTSKSFKK
                     PNSSVNSIKGLDSTLPALWDMQWDMKEITHNGESYNIESGSSNVTVGIVDSGIDIDHPD
                     LVDNLKSGSKNLVPKGGLRGTEPEETGDINSINDINGHGTMVAGSIAANGEIKGVAPNT
                     GIKVYRVFGNKSADAVWIIKAIIQAAKDDVDVINLSLGSYYIDGNIYKDDELLDNKWAD
                     VEGYKLAIEYANKLGSVVVASAGNDSIDVSNKSELNDFLKKKYAEEGKTFNGVGIEAPG
                     ELPGVVTVSSTGPTQQLSLFSNFGKNYIDIAAPGGDSRLLEKYGQEAWWDGGLFRQEQV
                     LTTFNTGRYLFASGTSMAAPKVSATLALIIDQRHYKNRPSNSIDYLYKNGVKKDIEPNL
                     AYWGNGQLDVYNAVK"
     gene            complement(2136..3563)
                     /locus_tag="HNP21_RS25570"
                     /old_locus_tag="HNP21_005269"
     CDS             complement(2136..3563)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013060068.1"
                     /locus_tag="HNP21_RS25570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005269"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_182527911.1"
                     /transl_table=11
                     /translation="MIKRLSLKNQFILTFASVIFLSLISTICSLVLLYYFLSVYNEKSV
                     QPANYYEKKVPSIEKFVELKGEKILEVSFQKNLEKVIPMEGITYQVINLRGNKIYGTLD
                     DQLIENNKSIYEKVNRSDQKGKVITKYLPILDKNRMEGVLAVRYVLASSIDYYIKYIFL
                     IILLIPFLFLTLYSYVFARRFGKELNKPIKELSAASQKIKNQDLDFEIKYESENEIGVL
                     IDSFNSMKEELKTSLYLQWKLEQERRDMVASIAHDLRTPLTIILSHVEVLMDPSLNGQK
                     RLPQYLQTIKNNTQRVLHLTEEMKRVSEVDNPDFTLDIEGVIPIEMLPEMLEEFKKWAE
                     DEEIKFTYSLNRKPGEGNSEFALDPKRLHQILTNLISNSIRFTPVNGSIDVQVQIEKDM
                     MSFSISDTGKGFNTKDLPFLFSKFYQGDPSRNDQLHHGLGLYIVKELVIKHGGEIHARN
                     NEPQGACIEFTISSINK"
     gene            complement(3563..4243)
                     /locus_tag="HNP21_RS25575"
                     /old_locus_tag="HNP21_005270"
     CDS             complement(3563..4243)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013060069.1"
                     /locus_tag="HNP21_RS25575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005270"
                     /product="response regulator transcription factor"
                     /protein_id="WP_013060069.1"
                     /transl_table=11
                     /translation="MQESILVVDDELEIVDIISDIFEDRGYRVLKAYNGEQALDQLKTN
                     VDLIILDVMMPQMDGFDLCKVIREQIYCPILFLSAKHSEMDKVKGFTLGGDDYITKPFQ
                     VKELIARVEAHLRREQRDRVSTQNQRLLGNLTINYSQHDVLLDGKKIDLTSKEFKILEL
                     LTVNLGQIFSKEQIYEKIWGIDAMGDLNTIIVHINNLRAKLTSGMSTYHIKTVWGVGYK
                     LEKR"
     gene            complement(4327..6168)
                     /locus_tag="HNP21_RS25580"
                     /old_locus_tag="HNP21_005271"
     CDS             complement(4327..6168)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1243: ABC
                     transporter, permease component"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013060070.1"
                     /locus_tag="HNP21_RS25580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005271"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_082352764.1"
                     /transl_table=11
                     /translation="MISMWKYITKNITRNLSHYTVYILSSILSVAIFYMYAAFLLYPKV
                     SGTEQLLIACEIIILLFSCFFIAYSHEHFLRERKKEMGIWKTFGASRKQLFNVLVLENA
                     VVGTFSILVGILFGMLLSKIFFNFMSDILFSNQSFVYTFSPVAVFVTVILFGIVFLLVS
                     CRSYFKIKRIAVLELFQEEKKPKPSAQFSRVKFILSICFLLVSYIFISYASLPMLLFAF
                     LPLLALLLVGTYLFCSNGLVGVISYLNNKEKRQLNGIKMLTLISLRKRLYYNAKIIFIV
                     SILLSAIMISIGAIQLYIEKNSQRMQSTHPQGALFVASKGKENKIEDIIAELKRQGIKD
                     LHMNKWKGLKISSESGKKQFLVIQNDPSFIKDEDSLKNNNYIFNNKKTDDITNEILKLK
                     SEKGERDLKVKNMNGKKVLNPIDGIEGIISVPKNTFSEIYKTTISEKRLSLYKLDFKED
                     AKIYNILKKLSDTTLFKSDNLHSIRLLDYENTVQLSSILRLTGLFICLVLFLALASLLW
                     FKLYEDMNDDKKVFHSLRKVGLTAKEIKRTLYIQISVIFFVPLSLGGLNLFIATNALQN
                     ILEGITIYSIIVIFLIFGVSQFIIYLISSYFYSKKVL"
     gene            complement(6140..6919)
                     /locus_tag="HNP21_RS25585"
                     /old_locus_tag="HNP21_005272"
     CDS             complement(6140..6919)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013060071.1"
                     /locus_tag="HNP21_RS25585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005272"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_029321001.1"
                     /transl_table=11
                     /translation="MAILEAREITKVYKTKYRTYPVLKNISLDIEEGDFVAIMGPSGSG
                     KSTLLNVLSSLDIPSEGDIKVGGTTLTGMKEEQLGIYRREHIGFIFQNYNLLDHLTIEE
                     NILLPAALKKGDKKGVQNKLQKFAEELEVTKFLTKYPYEVSGGQQQRAAIIRALINNPA
                     LLFADEPTGNLDSKSAQNVLHTLKMLNEKYKTTILMVTHDSVAASFCNRVIFLKDGQIV
                     HEMKRSKLEDTSKFNQRILSFIAKEVEDNDINVEIYN"
     gene            complement(6944..7705)
                     /locus_tag="HNP21_RS25590"
                     /old_locus_tag="HNP21_005273"
     CDS             complement(6944..7705)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013060072.1"
                     /locus_tag="HNP21_RS25590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005273"
                     /product="ABC transporter permease"
                     /protein_id="WP_013060072.1"
                     /transl_table=11
                     /translation="MKALFISEWERLWSQRKSKWMIGIFTVIVLLQAWFLRYYGVGIYN
                     NDQQVPLNTWNFPWFLLKESSFLLTLIFMPVFFLNSLNVEYNSGAYRLFLIRPFKRKSF
                     LISKWFSLALMVLVHLLIILGISIAFGFIFLKPDNDFTFYGQQKNAIEAILYTVQVYGL
                     FFIIQMCCLALASLISVIISNAVISFFLLIGLYVGCLYVSSQLSFFLLSVQSIFHTLST
                     TSNSLYVFAFVIMLVGFGACVRIWSKKEFTS"
     gene            complement(7723..8553)
                     /locus_tag="HNP21_RS25595"
                     /old_locus_tag="HNP21_005274"
     CDS             complement(7723..8553)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002161130.1"
                     /locus_tag="HNP21_RS25595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005274"
                     /product="ABC transporter permease"
                     /protein_id="WP_053488561.1"
                     /transl_table=11
                     /translation="MKGLFTSELERLWSQKISWIILFFIPLMSLGSVKYYLNWNERVSP
                     GQPDYVTSLNFPIISISEHLVVSFNIIAIILISTVIANEIENGQLRMILIRPFSTTQLF
                     LAKLATILTTMFLYLTLFWILNTVAGYIFFPKVNTLITFLDEQKLSLASALLYNVKYFF
                     ACFVTMISVVSVFTLLGSISRSTMITLGAGVGFIFLAIAIPQLLEFSTQTIIGHSTVVH
                     LMYMSIVKIQHTGIAFLLSSTNNLNSYIILVQAVYIALFGLIGYWTFVKRDYFI"
     gene            complement(8550..9284)
                     /locus_tag="HNP21_RS25600"
                     /old_locus_tag="HNP21_005275"
     CDS             complement(8550..9284)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058380.1"
                     /locus_tag="HNP21_RS25600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005275"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_013060074.1"
                     /transl_table=11
                     /translation="MKKEIVLEANNITKTVSGKNIVSQFSTKVYKGDICGFLGPNGAGK
                     TTVMRMFTGLIRPTQGTIMVGGKDVNKDRQQALRNVGAIIESPIFFPYMSGRKMLQNLA
                     RLYPDLSRKEQLEQVEAALSVVRLTEDADVKIKNYSLGMRQRLGIAQALLGEPDVILLD
                     EPANGLDPMGMRELRELILELREKKNLTFFISSHLLDEIQQMCDHLVIIRNGKLVTQGS
                     KEELIKDPSKRLEDVFVEMMTS"
     gene            complement(9371..9976)
                     /locus_tag="HNP21_RS25605"
                     /old_locus_tag="HNP21_005276"
     CDS             complement(9371..9976)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013060075.1"
                     /locus_tag="HNP21_RS25605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005276"
                     /product="flavoprotein"
                     /protein_id="WP_013060075.1"
                     /sec_met_domain="Flavoprotein (E-value: 1.8e-34, bitscore:
                     111.1, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVKNIVEKKILVGVSGSIAVAGIFQYLAMLKANFSEVKVVMTKG
                     AVQLIPAETVKLYCDEVFIDEKLSISGTIGHVELARWADLMAVLPATGNTLSKAAHGLA
                     TDLLSTVILAHDKPVIFFPNMNKLMWEKKVVQHNVKLLQQYDHIVVPPVKTTAFEIATM
                     SLRPNYVLPNPQNILNIISKQLEERNRLANICEKVEVQ"
     gene            complement(10001..11359)
                     /locus_tag="HNP21_RS25610"
                     /old_locus_tag="HNP21_005277"
     CDS             complement(10001..11359)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001177658.1"
                     /locus_tag="HNP21_RS25610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005277"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_053488562.1"
                     /sec_met_domain="LANC_like (E-value: 2e-71, bitscore:
                     233.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSTTDQKTYWLKGIDNETRNKALKLVLSIAEKLKDPSGIEKIVM
                     APDNVSLAGNLNPWDPITLSHGFPGTILLFGELDRQFPDSGFDLVAHNHLVEVQKVIER
                     QGVNSISMFGGITGVAYATLYISHNYERYSRFLQVLNNFILMQLEKILNEPEKELGVHP
                     LKYDVIQGMTGIGRYLIENTKHKENHEALKKILAYFVDMASDIEVNGEKVPGWYVSKAN
                     QLLEKDRIMFPEGNFNCGLAHGIPGPLSFMALSIQKGIEIPGQREAVLKITNWLMKWKQ
                     VDSGWPSRLSFQEVATSKISHSYPKRQGWCYGDPGVARSIYLAGKALGDTAAIRSAVGA
                     YQDIIVEPKEEWELVSPTFCHGRAGLLQMLIRMAKDEENQISVQSIVELVHYIEESYDP
                     NAPFGFRDIESNGEKSHQLNKAGLLEGVTGVLLPLLSLSSVEEPWWDGAFLLS"
     gene            complement(11384..13267)
                     /locus_tag="HNP21_RS25615"
                     /old_locus_tag="HNP21_005278"
     CDS             complement(11384..13267)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013060077.1"
                     /locus_tag="HNP21_RS25615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005278"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_013060077.1"
                     /transl_table=11
                     /translation="MKNTLDPTMENEKVSFVSILKSFRYWPSLFKLLWETHRGYFFCVL
                     VLNFLNGLLPASLILAIKYLVNMVQNLYIQGYKDNYFYDILPFFIFFSVVTLLTSATGS
                     ILETHKQLYRNLLSNKINVKLIEKAKRLPYASFENPEVYNKLQRARQDSTYKPFAIFEE
                     LMGIVKGAITLISISIILMVWNWEFTLILILLPLISAWSIVNVGKEIFLVSHKRAEETR
                     KQFYYYYLMTTDITVKEVKIFGLGSLLLRNYSDLFSKFYNQDRHLLLKKMRIDLSFQLI
                     SVIFVIFVQFMIVKDTIQGLIAIGSLIAYFQAVNTTQKTSNELMYMVFNMHQNNLYMTQ
                     LFSFLNVPESTDKPNVSEEKTLENVSSTEEGIQFLNVSFKYPGQENYTLKNVNFHIKPG
                     ETLALVGSNGSGKSTIVKLLTRLYTDYEGIILLNGKRIEDYQPQDWQDRISAIFQDFVR
                     YELDVKENIGYGDYKRSNHLVAIQAAAKRSGALTMIDSLPDKMDTQLGKTFANGIQLSG
                     GQWQRIAIARAYMRRASLYILDEPTAALDPAAEEEVFQDFQEIAQKSMGLFISHRYSTV
                     KYADRIIVLDKGEVAEYGTHVELLDTNGIYARLFNLQAKSYIEASATQASS"
     gene            complement(13233..16451)
                     /locus_tag="HNP21_RS25620"
                     /old_locus_tag="HNP21_005279"
     CDS             complement(13233..16451)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013060078.1"
                     /locus_tag="HNP21_RS25620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005279"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_182527912.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 4.4e-173,
                     bitscore: 569.4, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.5e-17,
                     bitscore: 56.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.3e-43, bitscore:
                     140.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILQKEKSNHKSSVTTENNLFEPLPFFMLRAPFLPTHTFDQLKDE
                     AVLVEKLRAYAEKDYVKEAIAIASPSLLNSLHYIHGDLNNRKTQQVLSSMLRYMLRMTT
                     RPTPFGAFSGVAAGQFKKNSSLKIDHFKEFKKRARPDMEWLLGVISVLERSNILPSLIV
                     DKNRASYVVGDRLHLPFSTECGQLRKKGMEKRENISIIYSEVVEKVLNLAEERITVREI
                     TQRLHTIYPNTDVTIIQRFIIQLLEQEYLITELRPPLTIDNPFNYLIRKLEEKDEKIEL
                     YEELLKVRELINTYNQLPLGEGLSLYSDLISQMRHIYEVTTPLQVDFSLNATDLTIGEK
                     VGEDISKAAQILWSIADEGVGFPHLQKYHVDFLEKYGTSREVPLLELLSEELGLGAPAS
                     YQNPHGNRGGDTTTSSINQERNSQLSYLLIKAIHNQEKEIEITEEIAQRMSKEKDRRYA
                     PDSLEVYGELHAASQEDLDQGNYTFCLSPNPGSNALGSTFGRFLDILDPDVSLKIQQYQ
                     QKIDLEFNEDTVMVEGSFLPATGRSANVAIGKTTRKVNVTLGTNGDEETIQLPIDDIVV
                     GASLENFYMKSKKLGKRIKVVAGNMLNYQSAPNIYRFMREISLNDLDQWRPFNWGSMAH
                     SPYYPRIRYKNIVLSPGIWKLNKEVFGMREKPQNEEEFFKAFGEWREKWSVPRNVFMTY
                     GDNRILIDLENTLHLRELKNELFKQGRLQLRETLQDRDQNCLNSPLGRHAVEIVVPLKK
                     TENTERRKKIGAIGEAKKDIVSNKIIYKLPGSEWLYVKLYAPNARENDLILKYLTPFAS
                     EMVKSDMASSWFFMRYRDPDAHIRLRFQGDPSKLSGLVLPRLREWADKLMDLGLLQKIT
                     IDTYEREVERYGGPMLIEKAEDYFHYDSQSVAMILSTLNQKNHLPAYVMASLSIIDIMD
                     NFGLNYAQQVASIENNTEKYEYIDEFRPLRKELSLIGDSRNDWENLRNYNSGVGKSIYE
                     SFLIRKESLTRYVTEIKELQKRDMLWNEHQMIMGAIIHMYCNRLLGANRELEKKALAFT
                     RHILSSQKYWRNKNEEYARSYNGK"
     aSDomain        complement(15678..15959)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HNP21_RS25620_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="7.00E-18"
                     /identifier="RREFam001.1"
                     /label="HNP21_RS25620"
                     /locus_tag="HNP21_RS25620"
                     /protein_end="258"
                     /protein_start="164"
                     /score="56.1"
                     /tool="antismash"
                     /translation="KNRASYVVGDRLHLPFSTECGQLRKKGMEKRENISIIYSEVVEKV
                     LNLAEERITVREITQRLHTIYPNTDVTIIQRFIIQLLEQEYLITELRPP"
     gene            complement(16537..16677)
                     /locus_tag="HNP21_RS25625"
                     /old_locus_tag="HNP21_005280"
     CDS             complement(16537..16677)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_b"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000606628.1"
                     /locus_tag="HNP21_RS25625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005280"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_013060079.1"
                     /sec_met_domain="TIGR03731 (E-value: 9.2e-20, bitscore:
                     63.1, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_b (E-value: 2.8e-10, bitscore:
                     32.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNVKNLFDLDVQVTTASSDVDPQITSVSLCTPGCGDTGSWNSFC
                     C"
     CDS_motif       complement(16606..16677)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNNVKNLFDLDVQVTTASSDVDPQ"
                     /locus_tag="HNP21_RS25625_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16537..16605)
                     /prepeptide="core"
                     /locus_tag="HNP21_RS25625_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="13.90"
                     /molecular_weight="2066.4"
                     /monoisotopic_mass="2064.9"
                     /core_sequence="ITSVSLCTPGCGDTGSWNSFCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNNVKNLFDLDVQVTTASSDVDPQ"
                     /leader_location="[16605:16677](-)"
                     /alternative_weights="2084.4"
                     /alternative_weights="2102.4"
                     /alternative_weights="2120.4"
     gene            complement(16752..16892)
                     /locus_tag="HNP21_RS25630"
                     /old_locus_tag="HNP21_005281"
     CDS             complement(16752..16892)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_b"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013060079.1"
                     /locus_tag="HNP21_RS25630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005281"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_013060079.1"
                     /sec_met_domain="TIGR03731 (E-value: 9.2e-20, bitscore:
                     63.1, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_b (E-value: 2.8e-10, bitscore:
                     32.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNVKNLFDLDVQVTTASSDVDPQITSVSLCTPGCGDTGSWNSFC
                     C"
     CDS_motif       complement(16821..16892)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNNVKNLFDLDVQVTTASSDVDPQ"
                     /locus_tag="HNP21_RS25630_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16752..16820)
                     /prepeptide="core"
                     /locus_tag="HNP21_RS25630_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="13.90"
                     /molecular_weight="2066.4"
                     /monoisotopic_mass="2064.9"
                     /core_sequence="ITSVSLCTPGCGDTGSWNSFCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNNVKNLFDLDVQVTTASSDVDPQ"
                     /leader_location="[16820:16892](-)"
                     /alternative_weights="2084.4"
                     /alternative_weights="2102.4"
                     /alternative_weights="2120.4"
     gene            complement(16967..17107)
                     /locus_tag="HNP21_RS25635"
                     /old_locus_tag="HNP21_005282"
     CDS             complement(16967..17107)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_b"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000606628.1"
                     /locus_tag="HNP21_RS25635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005282"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_013060079.1"
                     /sec_met_domain="TIGR03731 (E-value: 9.2e-20, bitscore:
                     63.1, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_b (E-value: 2.8e-10, bitscore:
                     32.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNVKNLFDLDVQVTTASSDVDPQITSVSLCTPGCGDTGSWNSFC
                     C"
     CDS_motif       complement(17036..17107)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNNVKNLFDLDVQVTTASSDVDPQ"
                     /locus_tag="HNP21_RS25635_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16967..17035)
                     /prepeptide="core"
                     /locus_tag="HNP21_RS25635_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="13.90"
                     /molecular_weight="2066.4"
                     /monoisotopic_mass="2064.9"
                     /core_sequence="ITSVSLCTPGCGDTGSWNSFCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNNVKNLFDLDVQVTTASSDVDPQ"
                     /leader_location="[17035:17107](-)"
                     /alternative_weights="2084.4"
                     /alternative_weights="2102.4"
                     /alternative_weights="2120.4"
     gene            17331..17504
                     /locus_tag="HNP21_RS25640"
                     /old_locus_tag="HNP21_005283"
     CDS             17331..17504
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030236.1"
                     /locus_tag="HNP21_RS25640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005283"
                     /product="hypothetical protein"
                     /protein_id="WP_182527913.1"
                     /transl_table=11
                     /translation="MTKTLWNFLMEMKKNNLTFENYELCPSLNTLSPEEKVVLNEYARS
                     LVLENEVGNEWV"
     gene            17491..18453
                     /locus_tag="HNP21_RS25645"
                     /old_locus_tag="HNP21_005284"
     CDS             17491..18453
                     /EC_number="2.5.1.-"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013060081.1"
                     /locus_tag="HNP21_RS25645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005284"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_053488454.1"
                     /transl_table=11
                     /translation="MNGFRSDLIDHINQHLSSYKQSGRAEVDLLALKHLSKRGKLLNQE
                     LSGFSWGELYLTLSYFLKRRKMTEEDFEKAFGIECIFLSADIVDDICDLDDPNLPTFQN
                     EDRYLILISQYLLAKGFFYLRPVSDSYEDNCLFSLIMDSGCGEWKDLHFRFSINKRVIP
                     TEEEYFKLIKQKSGKLTEIISQAIDPSQLILKKITYYIGIAGQLRNDAADVLNDKKSDL
                     RDLKAYLPFLKAYEYSCEVQDEFFHKLKDEEIMTSPLKRQLIREYIEQSGSIDYCHILS
                     RFYYMRAFKLLEEHFKLSKKEMNYFKSLFLQRSQQHEQA"
     gene            18440..20590
                     /locus_tag="HNP21_RS25650"
                     /old_locus_tag="HNP21_005285"
     CDS             18440..20590
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013060082.1"
                     /locus_tag="HNP21_RS25650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005285"
                     /product="sensor histidine kinase"
                     /protein_id="WP_013060082.1"
                     /transl_table=11
                     /translation="MNKHNLLICLPLGTLYIIIFMANGYYLYLSDFRRFVDSATLNSFY
                     VTSVISLIFFSIGLFSFFKKQKSIVIKNFFLLTSVSGIAISTSVLSSQDIPVFKTIEII
                     SVFMLSYLLLSFFAHFPVSTKPNYVKIIIFSSLLFSTLSSVVYLICNYLGYVEHSKFFY
                     IYRVLLIGNLFFSIVGCIFLISLHLKTNSLKVRNQLYILIFGIVFSFGPLFLFNLIPGM
                     IFGESQIPFVYCLPSIIVFPLTTSYLLVKHEIIEVELEISKWINILIYYILNFLLFSIL
                     IKQFMHLSNRELFVICSVGLLSAWASIFLYKIGINTFIQKKTKNRENTDLNEIELFQTL
                     SKEKHAKNLAKIIGKVIHQKFDINGLCIVWNSNNIYHSLHETGIFQTMNQFNFLNEINK
                     LEKDILLVEDQTPSIHMHFEKYHLICFPIAINQLVQGVIVIGEKNNHTLFQGKEFIELK
                     ELICESADILSSAAILNINDKQIRRTKTRVQNWNQFNHQVIQSLEKERKRLSIFLHDEI
                     LQSLILQLNEVRIMQTKRNFSVTLLDEMDDQLEGMIYNIRKMCHDLHPIIVEDLGLEPS
                     LQSLKREFELNYSILIHVQFNCEFKIISKNHEIQVYRIIKELLNNAVKHSKGKNIKVLI
                     LEENGFYQCSVKDDGIGFDVPDNFFDFSKGNHLGLLTIHRQIAELNGSMRISSDKGQGT
                     FVTFTIPLDWEDKNEYTYATSG"
     gene            20562..21170
                     /locus_tag="HNP21_RS25655"
                     /old_locus_tag="HNP21_005286"
     CDS             20562..21170
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002128205.1"
                     /locus_tag="HNP21_RS25655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005286"
                     /product="response regulator transcription factor"
                     /protein_id="WP_081113367.1"
                     /transl_table=11
                     /translation="MSIRTLLVDDHLLVMLGIRRLLESEEDIEIIDTVNDPSSLIEVVA
                     TTSPDVVVTDVRMKEFNGIELTKELLSKFPEIKVVILSGYDHEEYYNAAFKAGASAYIT
                     KERSAFDLANAIRQSNMGYILFSKNQISTKDFETLTSAEQKILLLISKDKTNYEISMDL
                     SISKRTVEYHISSIIRKLDVDSRVGAVVKGIKKGLIEDF"
     gene            complement(22475..22984)
                     /locus_tag="HNP21_RS25660"
                     /old_locus_tag="HNP21_005288"
     CDS             complement(22475..22984)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016134870.1"
                     /locus_tag="HNP21_RS25660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005288"
                     /product="DinB family protein"
                     /protein_id="WP_053488456.1"
                     /transl_table=11
                     /translation="MNQRPSEEEYAWAIGEYIRLVPDGNIIDILLSQEKQMTELLASLT
                     ESHGAYRYAEGKWTLKEVVGHIADGERVMTYRLLRFARGDQTPLSGFDQELFMPPFGCW
                     STAQLAEDYRAVRQSTITLLRGLPAEAWSRKGTANNASITARALAYGIAGHEIHHMGVI
                     RTRYLS"
     gene            complement(23321..24028)
                     /locus_tag="HNP21_RS25665"
                     /old_locus_tag="HNP21_005289"
     CDS             complement(23321..24028)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012259899.1"
                     /locus_tag="HNP21_RS25665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005289"
                     /product="IS6 family transposase"
                     /protein_id="WP_182527914.1"
                     /transl_table=11
                     /translation="MEKENVFKWKHYQPDLILLNVRCYLRYNLSFRDLIEMMEERGLCI
                     AHTTIMRWVHQYGPELNERVRRHLKPTNDSWRVDETYVKVKGQWMYLYRAVDSEGNTID
                     FYLSKARNKQAAKRFFKKALAFSHVSIPHTITVDKNPAYPIAIQELKKEKKMPEGIQIR
                     QIKYLNNIVEQDHRFIKKRLSTMLGLKTFRTAKAIISGIEVMHMMKKKQVYQEVKSVQN
                     QISFIHQLFVIAA"
     misc_feature    24169..24183
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.86"
                     /tool="antismash"
     gene            24253..24879
                     /locus_tag="HNP21_RS25670"
                     /old_locus_tag="HNP21_005290"
     CDS             24253..24879
                     /EC_number="3.2.-.-"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014458906.1"
                     /locus_tag="HNP21_RS25670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005290"
                     /product="type 1 glutamine amidotransferase family protein"
                     /protein_id="WP_182527915.1"
                     /transl_table=11
                     /translation="MQIKKVYIYVFNTMSDWEYGYLIAELNSGRYFRQGLAPLKVMTVG
                     VNKEIIKTMGGLSIQPDSSLDECTLLDKDLLILPGGNTWSEEIHQPILKKVGEVLELGT
                     IVAAICGATDALANSGYLDSRKHTLNNLEYTKMVCPNYKGEKLYEVGPVVSDNNMITAS
                     GVAPLEFARDVLKKLDVFASNTLDSWYRLNKTQKSEYFFQLMSSI"
     gene            complement(25126..25548)
                     /locus_tag="HNP21_RS25675"
                     /old_locus_tag="HNP21_005291"
     CDS             complement(25126..25548)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016766081.1"
                     /locus_tag="HNP21_RS25675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HNP21_005291"
                     /product="hypothetical protein"
                     /protein_id="WP_182527916.1"
                     /transl_table=11
                     /translation="MDMSNIAKWIPVPYFQIRQDGTILNSSNITHSYFQSTSSIWNIIY
                     KEDRNKAILMLSQITNSYPVTQYLILQTSNKLFMNFKCTIQWQDSIGHLVCTEAKNIKA
                     PSVLSVQKSLVNTQKRLEESEKHLNNVIKILDIRKH"
     misc_feature    complement(25645..25659)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.15"
                     /tool="antismash"
     misc_feature    26238..26253
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.75"
                     /tool="antismash"
ORIGIN
        1 ttttttatgc aaaccaattg caaaaatttg cgatatgatg aaggcttgtt attattcctt
       61 tggtgttctc ttttttactt aaaataaaag aataaaatgc aacttctaga gcaaactaag
      121 aggataggaa ccccaattcc tactattctt catgtatgat gttctaagga aaagctactt
      181 ccatgggtaa gggagtagct tttttcttta gagtttacat aagtttgatt atggtaacta
      241 gatatgtatg aaacacttgg gttaattgat tataaattac tagctcttat acttgtccta
      301 tctttttctt atatttgtac agatatatct tttcagcaat ataacaagca attaagccag
      361 caataattgg tagcattgag cctgcattta tataaagtcc atctcttccc agtcaaaact
      421 gagttaaccc attttatcga gaaatataaa gagcaataca caggagtaaa gaacaaactt
      481 tataaaattt atgtgttttg cgggatatac tagttattta ttcgatatat tcagattata
      541 aatctatcat tattcgttat cttatattta taggatctag gtggaatagc caagtggtta
      601 aggcaaaggt ctgcaaaacc ttgatctccg gttcaatccc ggattccacc tctaaattat
      661 aaatataagg agaagattat gaaaaaaacc tctatgacta ttattactac tctcttaatt
      721 tgcttttgtt ttactaatta tgggcatgct aaaacagaaa caaatcaata ttacacagtt
      781 atcttgaaag accgttctaa gtggacgcaa tctattaaga agattaaaaa gagccaggga
      841 gaaattactt ataccgtccc tgagatagga ctaattcaat ttaaaggaaa tcaaaaagtg
      901 gctaaaacaa atgcttcttt atttaaatct ttaagtcctt ctttaaaatt agaaaagcct
      961 tctacatcta catctaagtc ttttaaaaaa cctaattcaa gtgtaaactc aataaaaggt
     1021 ttagatagca ctcttcctgc cttatgggat atgcagtggg atatgaaaga aattacgcac
     1081 aatggagaaa gttataacat agaatcaggt tcttctaatg taactgttgg aattgttgac
     1141 tctggaattg acattgacca tccagacctc gtagacaatc tgaaaagtgg atcaaaaaat
     1201 cttgttccca aaggtgggct tagagggaca gagcctgaag aaacaggcga tattaatagt
     1261 attaacgata ttaatggaca tggaactatg gtagctggat ctattgctgc caatggtgaa
     1321 attaaagggg tagcaccgaa tacaggaatt aaagtatatc gtgtattcgg taataagtca
     1381 gctgatgctg tgtggatcat caaagcaatt attcaagcag ctaaagatga cgtggatgtc
     1441 attaatctta gccttggttc ttattatatt gatggtaaca tatataaaga tgatgaactt
     1501 ttagataata agtgggcaga tgttgaagga tataaacttg caattgagta tgctaataag
     1561 ttaggtagtg tggtagttgc ttctgcaggc aatgactcaa tagatgtttc caacaaatca
     1621 gagctgaatg attttcttaa gaaaaaatat gcggaagaag gaaaaacatt taacggagta
     1681 ggaattgaag ctccaggaga attgcctggt gtagtcacag tatcttctac tggtcctacg
     1741 caacaacttt ctttattctc taatttcgga aaaaattata ttgatatcgc tgctccaggg
     1801 ggagattcta gattgttaga gaaatacggc caagaggcat ggtgggatgg tggacttttc
     1861 cgacaagaac aagtattaac tacttttaac actggaagat atttatttgc ttctggaact
     1921 tcgatggctg cacccaaggt ttctgctacc ctcgccttaa ttatcgacca acgtcactac
     1981 aaaaaccgtc caagtaactc cattgattat ctatacaaaa acggagtaaa aaaagatatt
     2041 gaacctaatt tagcttattg gggaaatggt caactggatg tatacaacgc ggttaaataa
     2101 ataaaaaatg aactatgata ctcatagttc attttttatt tatttatgga agatatggtg
     2161 aattcaatac atgctccttg aggttcatta tttctggcat gaatttctcc accatgtttt
     2221 ataactaact cttttacaat atataacccc aacccatggt gaagttggtc attccttgaa
     2281 ggatctcctt gatagaattt actgaataaa aaaggtaaat ctttggtatt aaatcctttt
     2341 cccgtatcgg aaatagaaaa agacatcata tctttctcta tctgaacttg aacatcgata
     2401 ctcccattca ctggggtaaa acgaatgctg ttagaaatta agttagtcag aatttgatgc
     2461 aatcgttttg gatctaatgc aaattcggaa tttccctctc caggctttct attcaagctg
     2521 taagtaaact ttatttcttc atcctctgcc cattttttaa attcctctag catttccggt
     2581 aacatttcta taggaataac accttcaata tcaagtgtaa aatctggatt atctacctca
     2641 gacactcttt tcatttcctc tgtcaaatgc aatactcttt gggtattatt ttttattgtt
     2701 tgcaaatatt gtggcaaacg cttctgtcca tttaatgatg gatccattaa gacctctaca
     2761 tgggataata taattgttag aggcgttctt aaatcatggg caatcgaggc aaccatatct
     2821 cgacgctctt gttctaattt ccattgaaga taaagtgacg ttttcaactc ttctttcata
     2881 ctgttaaaag agtcaattaa tacacctatt tcattttcac tctcatattt aatctcaaaa
     2941 tccaaatctt gatttttaat tttctgagaa gcagcactca gttctttaat cggcttattt
     3001 aattctttcc caaaacgtct cgcaaatacg tatgagtaaa gtgttaaaaa taaaaaagga
     3061 attaataata ttataagaaa tatgtatttt atataatagt caatagatga tgctaacaca
     3121 tatcgtacag ctagaactcc ttccattcga tttttgtcga ggataggaag atatttcgtt
     3181 atgaccttcc ctttttgatc ggatctatta actttttcat atatactttt gttattttct
     3241 attaattggt catctaatgt accatatatt ttatttcctc gaaggtttat gacctgatat
     3301 gtaattcctt ccataggaat aactttttct aaatttttct gaaaagatac ttctaatatc
     3361 ttttctcctt ttaactcaac aaatttttct atgctaggaa cttttttctc gtaataatta
     3421 gcaggttgga ctgacttttc attataaacg gagagaaaat aatataataa aactaagctg
     3481 caaattgtac ttataaggct taaaaagatt actgaagcaa aggttaaaat aaactgattt
     3541 tttaaagata gccgtttaat cattaacgtt tttccaactt atatcctact ccccacaccg
     3601 ttttaatgtg ataagttgac atacctgaag tcaatttagc tcttaaatta ttaatgtgaa
     3661 ctataatagt atttaagtca cccattgcat caatacccca aattttctca taaatctgtt
     3721 ctttagaaaa tatttgtcct aagtttactg ttaaaagttc caatatctta aactctttac
     3781 ttgttaagtc tatcttttta ccatccaata aaacgtcatg ttgtgaataa ttaatagtta
     3841 aattacctaa gagacgttga ttctgagtac taactcgatc cctctgttca cgtcttaagt
     3901 gcgcctctac ccgagcaata agttctttca cttggaaagg cttcgttata taatcatctc
     3961 ctcctaaagt aaatcccttt actttatcca tctctgagtg cttcgcactt agaaacagaa
     4021 taggacaata aatttgttct ctgataactt tacaaagatc aaaaccatcc atctggggca
     4081 tcataacatc taatattatt aaatctacat ttgtctttaa ttgatctaat gcttgctccc
     4141 cattataagc tttaagaact ctataacctc ggtcttcaaa gatatcagag attatatcta
     4201 caatctccag ctcatcatcg actacaagaa tactttcttg cataagtata tacctccccg
     4261 cccccctagt attttaatta tctaggagag ataaattagt accctcctag acaaaatatc
     4321 atcttttcat agaacctttt tagagtaaaa gtaactagaa ataagataga taataaactg
     4381 agacactcca aatattaaaa atattactat tatagaataa attgtaattc cttctaatat
     4441 attttgcaag gcattagtag ctataaataa attcaatccc cctaacgata aaggaacaaa
     4501 gaatattacc gaaatttgaa tgtacaaagt ccttttaatt tctttagcag taagacccac
     4561 ttttcgtaat gagtggaata cttttttatc atcgttcata tcttcataca gtttaaacca
     4621 aagcagacta gctaaagcaa gaaacaaaac taagcatata aacagtcctg taagtctcaa
     4681 tattgaagat aattgaactg tattttcata atcgagaagt cgaatactat gaagattatc
     4741 cgatttgaac aaggttgtat ctgataattt ctttaaaatg ttataaattt ttgcatcctc
     4801 tttaaaatct aatttataga gtgacaatct tttttcagaa atcgttgttt tatatatttc
     4861 actaaaagtg tttttcggta cagagataat accctcaatt ccatctatag gattaagaac
     4921 ttttttaccg ttcatatttt ttacttttag atctctctcc cctttttcag attttaattt
     4981 taagatttca ttagtaatat catcagtttt tttattatta aaaatataat tattattttt
     5041 taacgaatct tcatctttta taaaagatgg gtcattctgt attactaaaa attgcttctt
     5101 cccactctct gaagaaattt ttaatccttt ccacttattc atgtgtaaat cctttattcc
     5161 ttgtctcttc aattcagcta taatatcttc tattttgttt tccttcccct ttgatgcaac
     5221 aaataatgct ccttgagggt gagtgctttg cattctttga ctgttctttt ctatatataa
     5281 ctgaatagca ccgattgata tcataattgc agataataga atagatacga tgaagataat
     5341 ctttgcatta taatataatc tttttctcaa acttataaga gttaacatct ttatcccatt
     5401 caactgccgt ttttctttat tattcaaata agatattaca cctactaaac catttgaaca
     5461 gaataggtat gtgcctacta gtaataatgc taataggggt aaaaaagcaa ataatagcat
     5521 aggtaaagat gcataagaga taaatatata agaaaccaaa agaaagcaga tagataaaat
     5581 gaatttaacc ctagagaatt gagctgaagg tttaggtttt ttttcttctt gaaataactc
     5641 tagaactgca attcgtttaa tcttgaaata actacgacat gaaacaagta aaaatactat
     5701 tccaaataaa ataaccgtaa caaaaacagc cacgggagag aaagtataaa cgaacgattg
     5761 atttgaaaat agaatatcac tcatgaaatt aaagaaaatc tttgataaca gcattccaaa
     5821 taaaatgcca actaaaatag aaaacgtacc aactacggcg ttctctaaaa cgagcacgtt
     5881 aaacaattgc tttctagagg ccccaaatgt tttccaaata cccatttctt tttttctttc
     5941 tctaaggaaa tgctcatgtg aatatgcgat aaaaaaacaa gaaaatagca aaataataat
     6001 ttcacatgca attaataact gttctgttcc cgaaaccttt ggatataaaa gaaaggctgc
     6061 gtacatataa aaaattgcta cagaaagaat gctactaagt atgtatactg tataatgaga
     6121 aagattacgg gttatattct tagttatata tttccacatt gatatcatta tcctccactt
     6181 ccttagcgat aaaagataag attctttgat tgaacttaga cgtatcttct aatttggaac
     6241 gcttcatttc atggacaatt tggccatcct ttaaaaatat gactctgtta caaaagctag
     6301 cagctaccga atcatgagtt accattaaaa tagttgtttt gtacttttca tttaacattt
     6361 ttaaagtatg tagaacattt tgagcagatt tagaatctaa attccctgta ggctcatcag
     6421 caaataataa agcaggattg ttaataagag cacgaatgat ggcagctctt tgctgttgcc
     6481 ccccagagac ttcataagga tatttagtta aaaattttgt cacttccaac tcttcagcaa
     6541 atttttgaag tttattctgt acacctttct tatctccttt ttttaaagca gcaggtaata
     6601 aaatattttc ttcaatagtc aaatgatcta acaagttgta attttgaaag atgaaaccaa
     6661 tatgctcacg tcggtaaata cctaattgtt cttctttcat acctgtgaga gtagttcccc
     6721 cgaccttgat atccccttct gaggggatat caagggaaga aagcacattt aataaggtag
     6781 actttccact tcccgaagga cccataattg ctacaaaatc gccttcttca atatctaaac
     6841 ttatattctt taagacaggg tacgttctgt acttagtttt ataaactttt gtaatttctc
     6901 gtgcttccaa tatagccatt ttaattcttc ctcctatctt tatttaagaa gtaaattctt
     6961 ttttactcca aatccttaca caagcaccaa aaccaactaa cataataaca aatgcaaaaa
     7021 catataaaga attgctagta gtactcagag tatgaaagat actttgaact gataataaga
     7081 aaaatgaaag ttggctggaa acatacaaac aacctacata taacccaatt aacaagaaga
     7141 agctaataac tgcatttgaa ataattacac taattaaact agcaagagct aaacagcaca
     7201 tctggatgat gaaaaagaga ccatacactt gtactgtata taatatagct tctatagcat
     7261 tcttctgttg accataaaaa gtaaaatcat tatctggttt taagaagata aaaccaaacg
     7321 ctatactaat ccctaggata attaataaat gtactagtac cattaaggca agagagaacc
     7381 attttgaaat tagaaatgat tttcttttaa aaggtctaat taaaaaaaga cgatatgctc
     7441 ctgagttata ttctacatta aggctattca gaaaaaatac tggcataaag atcaatgtaa
     7501 gtaagaatga agattctttt aataagaacc atggaaaatt ccaagtattt aaaggaactt
     7561 gctgatcgtt attgtaaatt ccaactccat agtatcttaa gaaccaagct tgaagaagta
     7621 caattacagt aaaaatccca atcatccatt tactttttct ttggctccaa agtctctccc
     7681 attcgcttat aaataatgct ttcaattaaa accctccttg agtcaaataa aataatctct
     7741 cttcacaaat gtccaataac caattaagcc aaatagagca atgtatacgg cttgaactaa
     7801 aatgatgtaa gaatttagat tgttagttga tgaaagtaaa aacgctattc ctgtgtgctg
     7861 aattttcacg atagacatgt acataaggtg aaccactgtg ctgtgcccga taattgtttg
     7921 cgtcgagaat tctaagagct gaggaatggc aattgctaag aaaataaagc caacccctgc
     7981 cccaagtgtt atcattgtac ttctgcttat cgatcctaat aatgtaaaaa ctgatacaac
     8041 gctaatcatt gtcacaaaac aagcaaagaa atattttacg ttatataata aagctgatgc
     8101 taaagataat ttctgctcat ctagaaatgt tattaaggta ttaaccttag gaaaaaagat
     8161 ataaccagca acggtattta aaatccaaaa tagagttaaa tacaagaaca tggttgttaa
     8221 aatagtagct aattttgcta aaaaaagttg agtggtagaa aaagggcgga tgaggatcat
     8281 tcttagttgc ccattttcta tctcattagc tataaccgta gaaattagta ttatagctat
     8341 gatattaaaa gaaacaacga gatgttcaga aatgctaatt atagggaagt tcaaagaagt
     8401 tacataatct ggttgtcctg gtgacactcg ttcattccaa tttaagtaat atttaactga
     8461 acctagcgac attaagggta taaaaaatag tatgatccat gatatctttt gggaccataa
     8521 tcgttctaac tctgaagtga aaagtccttt catgatgtca tcatctccac aaatacatct
     8581 tccagtctct tgcttggatc tttaattaac tcttctttac ttccttgtgt aacaagttta
     8641 ccgttacgaa taatgacaag atgatcacac atttgttgga tttcatcaag taaatgacta
     8701 gaaatgaaaa atgttagatt tttcttttct cgaagttcaa gaattaattc tcttaattct
     8761 ctcattccca tagggtcaag accatttgct ggctcatcta ataaaatgac atctggttct
     8821 cctaagaggg cttgagcaat tcccagcctt tgtcgcatac ctaatgaata attcttaatt
     8881 tttacatcgg catcttccgt tagtcttaca acagataatg ctgcctccac ttgctctaac
     8941 tgttcttttc tcgaaaggtc gggatatagc ctcgctaaat tttgtaacat ctttctgcct
     9001 gacatatacg ggaaaaagat aggggactct ataatcgctc ctacatttct taaagcctgt
     9061 tgtctatctt tatttacatc tttaccccct accattattg tgccttgagt agggcgaata
     9121 agccctgtaa acattcgcat aacagttgtt tttccagctc catttggtcc caaaaacccg
     9181 catatatctc ctttatacac cttagttgag aattgactta caatattctt tccactcact
     9241 gtttttgtga tattatttgc ttctaaaaca atttcttttt tcatattcaa tccctcctta
     9301 tgttttaata taaaagacaa atataaataa aaaataaaga aaagaaaaaa actcacattt
     9361 ttgtgagttt ttattgaact tcaacttttt cacaaatatt cgctagtcta tttctttctt
     9421 ctaattgttt agaaatgatg ttcaatatat tttgcggatt aggtaaaaca tagttaggtc
     9481 tcaatgacat agttgcaatt tcaaaagctg ttgtttttac aggaggtaca acaatatgat
     9541 catattgttg tagtagctta acattatgct gaactacttt cttttcccac attaatttat
     9601 tcatgtttgg aaaaaagata acaggtttat catgagctag tattactgta cttaataaat
     9661 cagttgctag accatgagct gctttagata atgtgtttcc tgtagctgga agtacggcca
     9721 ttaaatcggc ccacctcgct aattccacat gtcctatggt tccacttatg ctaagctttt
     9781 catcaataaa tacctcgtca caatataact ttactgtctc agctgggata agttgaactg
     9841 cacctttcgt cattacaact tttacctcac taaagtttgc ctttagcata gctaaatatt
     9901 gaaaaatgcc tgctactgca atcgacccac ttacccctac tagtattttt ttctctacaa
     9961 tattcttaac gtccatttat catagccccc tgaatcttaa ttaagaaagt aaaaatgccc
    10021 cgtcccacca aggttcttcc actgaactta aacttagtaa aggtaataat acgccagtta
    10081 caccttcgag taatccagcc ttgtttaatt gatgtgactt ctctccattg gattctatat
    10141 ctctaaaacc aaagggtgca ttagggtcat atgattcttc tatataatgt actaactcta
    10201 ctattgattg aactgagatt tgattctctt catcttttgc catccttata agcatttgta
    10261 ataatcctgc tcttccatga caaaatgttg gcgatactaa ttcccattct tcttttggtt
    10321 ctactattat gtcctgataa gctcccactg cactccttat tgctgctgtg tcgcccaagg
    10381 cctttcctgc taaatatata cttctcgcta cgcctgggtc tccataacac cagccctgac
    10441 gttttggata agaatgagat attttagaag tggctacttc ttgaaaacta agtctggaag
    10501 gccaaccact gtctacttgt ttccacttca ttaaccaatt ggtaatcttg agtacagctt
    10561 ccctctgacc aggtatttca attccctttt gaatcgataa agccataaaa gacagtggac
    10621 ccggtatgcc atgagcaaga ccacaattaa aattcccttc tggaaacata attctatctt
    10681 tttctagtag ttgattcgct tttgaaacat accaccccgg tactttttca ccatttacct
    10741 cgatatcaga agccatatcc acaaaataag caagtatttt ttttagtgcc tcatgatttt
    10801 ctttatgctt cgtattttca atgagatagc gacctattcc tgtcattcct tgtatcacat
    10861 catattttag aggatgtaca cctagttcct tctctggttc atttaatatc ttttctaatt
    10921 gcatcaatat aaaattattt aagacttgga ggaatctaga atacctctca taattatggg
    10981 atatatataa cgtggcataa gcgacacctg ttatacctcc aaacatcgaa atactattga
    11041 ccccttgcct ttcaataacc ttctgtactt ctactaaatg gttatgtgcg acaaggtcaa
    11101 acccactatc agggaactga cggtcaagtt ctccaaataa taaaatagtg cctggaaaac
    11161 catgggacaa tgtgataggg tcccatgggt tcaaattacc tgccaatgat acgttatcag
    11221 gagccattac tatcttttct ataccacttg gatcctttaa cttttcagct atgcttaaca
    11281 ctaattttag tgctttattt cttgtctcat tatcaattcc ctttaaccaa tacgtttttt
    11341 ggtcagtagt agatggcata attttctcct ttctccttac atcttatgag cttgcttgtg
    11401 ttgcactagc ttctatataa ctcttagctt gcagattaaa taatctggcg tatattccat
    11461 ttgtgtctaa aagttctaca tgagtcccat actccgcgac ctctccttta tcaagtacta
    11521 taatcctgtc agcgtatttt acggttgagt agcgatgaga tatgaaaagt cccatacttt
    11581 tctgagcaat ctcttgaaaa tcttgaaaaa cttcttcttc ggctgctgga tctaaagcag
    11641 cagtcggttc gtcaagaata tataaacttg ctcttctcat ataggctcgc gcaatagcaa
    11701 ttctttgcca ttggcctcca gataattgaa taccgttagc aaaagttttt ccgagctgag
    11761 tatccatttt atcaggcaag ctatcaatca ttgtaagcgc tccggacctc ttagctgctg
    11821 cttgtatagc tactaaatga ttagaccttt tgtaatcacc ataaccaatg ttttctttga
    11881 catctaactc atatctcaca aaatcttgga aaatagcact aattctatcc tgccaatctt
    11941 gcggctgata gtcctcgatt cttttaccat tcaagagaat aatcccctca taatctgtat
    12001 atagtcgtgt tagcagctta acaattgttg attttccaga tccattagat cctactaaag
    12061 ccaaagtctc tccaggttta atatgaaaat taacattttt taatgtgtaa ttctcttgcc
    12121 ctggatattt aaaggataca tttaaaaatt gaataccttc ttccgttgaa gagacatttt
    12181 ctaacgtttt ttcctctgag acattaggtt tatctgtgct ttctggaaca ttaaggaagg
    12241 aaaataattg tgtcatatat agattgtttt gatgcatgtt aaaaaccata tacattaact
    12301 catttgacgt tttttgagtc gtgttgacag cttgaaaata agcaataagg ctaccaatag
    12361 caattaatcc ctggattgta tctttaacaa tcataaattg aacgaatatt acaaaaatta
    12421 cacttatcaa ttgaaaagat aaatcaattc tcatcttttt taaaagcaaa tggcgatcct
    12481 gattatagaa cttactaaat aagtctgaat agtttcttag tagtaagctg cctaacccaa
    12541 atattttaac ttctttaacg gtaatatcag tggtcattag atagtagtaa taaaactgtt
    12601 ttcttgtctc ctctgctcgc ttatggctta ctaaaaatat ttcttttccc acattcacaa
    12661 tagaccaggc ggatattaaa ggtaataaaa ttaagatcaa tgtaaattcc cagttccaaa
    12721 ccattaaaat tattgaaata gaaattaaag taatagcacc ttttacgatc cccattaact
    12781 cttcaaaaat agcaaacggc ttatacgtgg aatcttgcct tgctcgttgg agtttattgt
    12841 atacctctgg gttttcaaag cttgcataag gtagtctttt cgctttttca atcaatttta
    12901 catttatctt gttagacagt aggtttctgt atagttgctt atgcgtttct aggattgaac
    12961 cggtagcgct ggttaataaa gtgacaactg aaaagaagat aaaaaaaggt aaaatgtcgt
    13021 aaaaatagtt atctttgtac ccttggatat acagattttg caccatattt acaagatatt
    13081 ttattgctaa aatcaaggaa gctggtaata gcccatttag aaaatttagg acaagaacac
    13141 agaagaaata tcctctgtgt gtctcccaca aaagcttaaa tagactcggc cagtatcgaa
    13201 aagattttag aatgctaaca aatgatactt tctcattttc cattgtagga tctagcgtat
    13261 tcttcattct tattcctcca atacttctgg ctggacaaaa tatgtctagt aaaagctaat
    13321 gctttcttct ctaattctct atttgctcct aataatcgat tacagtacat atgaataatt
    13381 gctcccataa tcatttgatg ctcattccaa agcatatctc ttttctgtaa ctctttaatt
    13441 tcagtcacat aacgggttaa agattcttta cgaatcaaga aactttcata tatagactta
    13501 ccgactccag aattataatt acgcaagttt tcccaatcat ttcgtgaatc tcctattaga
    13561 gataattctt ttcgcaacgg tctaaattca tctatatact catatttttc tgtattattt
    13621 tctatagagg ctacttgttg cgcgtaattc aacccaaagt tatccatgat gtctataatt
    13681 gagagcgatg ccattacata agctggaaga tgattttttt gatttaacgt actgagaatc
    13741 atggctacag actgactatc gtaatgaaaa taatcctcag ctttttctat taacatggga
    13801 ccaccataac gctctacttc tcgttcatat gtgtcgatag taatcttttg gagtaatcct
    13861 aaatccatta gtttatctgc ccattccctt aaacgaggaa gaactagacc actaagttta
    13921 gaagggtctc cctgaaagcg taaacgaata tgtgcatcag ggtctcggta acgcataaag
    13981 aaccatgatg atgccatatc acttttaacc atttcactag cgaaaggcgt aagatatttt
    14041 agtattaagt cattctctct tgcgtttgga gcatagagtt ttacatataa ccactcgctc
    14101 cctggtaatt tgtagattat tttattactt acaatatctt ttttcgcttc ccctattgca
    14161 ccaattttct ttcttcgctc agtattttct gttttcttta aaggaacaac tatttctaca
    14221 gcatgtctcc ctaaagggct atttaagcaa ttttgatccc gatcttgaag agtttctctt
    14281 aattgcaacc ttccttgctt gaataattca ttttttagtt cacgtaggtg taaagtgttc
    14341 tccaagtcaa ttaagatgcg attgtctcca taagtcataa atacattacg aggaactgac
    14401 cacttttcgc gccattctcc aaaagcttta aaaaattctt cctcattctg aggcttctct
    14461 ctcataccga aaacctcttt atttaatttc caaataccag gcgaaagaac aatgttttta
    14521 tagcgaattc ttggatagta aggagagtgt gccatacttc cccaattaaa tggtcgccat
    14581 tggtctaaat cattgagtga aatctccctc ataaaacgat aaatattagg cgcactttga
    14641 taattaagca tgttaccggc tactacttta attcgtttgc ctagtttttt tgacttcata
    14701 tagaagttct ctaacgatgc tcctaccaca atatcatcga taggtaactg gattgtctct
    14761 tcatcaccgt ttgttcccag agtgacgttc acttttcttg tcgtttttcc aattgctacg
    14821 ttggctgatc ggccagttgc tggcagaaag gagccttcta ccatcacggt atcttcgttg
    14881 aattcaaggt caattttttg ttgatactgt tgtattttta acgaaacatc cggatctaag
    14941 atatctaaaa accgaccaaa tgtgctacct aaggcattag atccagggtt aggacttaaa
    15001 cagaatgtat agttaccttg atctaagtcc tcttgtgaag cagcatgtaa ctctccatat
    15061 acttctaaag agtcaggcgc atatcttcta tctttttctt tactcattct ctgagctatt
    15121 tcttctgtaa tctcgatttc tttttcttga ttatgaatag ctttaataag aagatatgat
    15181 aactgactat tacgttcttg atttatagaa gaggtggtag tatctcctcc cctattccca
    15241 tgtggatttt gataagaggc aggtgcaccg agacctaact cttcacttaa taattctagt
    15301 aaaggaactt ctctagatgt tccgtatttt tctaaaaaat caacatgata cttttgtaaa
    15361 tgtggaaatc ccactccctc atcagctatc gaccataata tttgggcagc tttgcttatg
    15421 tcttctccta ccttttctcc aatagttaag tctgtggcat ttaaggagaa atctacttga
    15481 aggggagttg taacttcata aatatgtcgc atttgtgaaa tcaaatcact ataaagggag
    15541 agaccttctc ctaatggtaa ttgattataa gtattgatta gttcccttac ctttaacagt
    15601 tcctcataga gctctatctt ctcatctttt tcttctaatt ttctaatgag ataattaaat
    15661 ggattatcaa tagttaaagg aggccttagt tccgttataa gatattcttg ttccaatagc
    15721 tgtataataa agcgttggat tattgtcaca tctgtatttg gataaatagt atgtaacctt
    15781 tgtgtaattt ctctcactgt tattctttcc tcagctaaat taagaacctt ttcaaccact
    15841 tcgctataaa ttatggaaat attttctctt ttctccattc ccttttttct aagttgacca
    15901 cattcagttg aaaatggcaa atgaagacga tcgcctacta catacgatgc acgattctta
    15961 tctacaatta gagaaggaag gatattgctt ctttctaaaa ctgaaataac tcccaaaagc
    16021 cactccatat ctggtcgtgc cctcttctta aactctttga aatgatctat tttcagggaa
    16081 gaattctttt taaattgtcc agctgctact cctgaaaaag ctccaaaagg agttggtcta
    16141 gttgtcattc ttaacatgta acgcaacata gaagataaaa cttgttgggt ttttctatta
    16201 tttaaatcac catgtatgta atgaagggaa tttaatagag aaggacttgc aatagcaatg
    16261 gcttctttta cataatcttt ttctgcataa gctcttaact tttccactaa tactgcttcg
    16321 tctttaagtt ggtcgaaggt atgggttggt aaaaacgggg ctcttaacat aaaaaatgga
    16381 agaggttcaa ataaattatt ttcagtagtt acgctagatt tatgattgga tttttctttt
    16441 tgtaatatca attttaatct ccctttcctt ttataatata attcaaaaga agagaaaaga
    16501 gggaacaaca ttgtttccct ctttttcaac ttctaattag cagcagaagc tgttccaact
    16561 acctgtatct ccacaacctg gtgtacataa agatacactt gtaatttgtg gatctacatc
    16621 acttgaagca gttgttactt gtacatctaa atcaaaaagg ttttttacgt tattcatttt
    16681 tcattccccc agaaagtttt tattaagaat tacatctttt tcatttcctt cttataaagc
    16741 tctattacta attaacagca gaagctgttc cagctacctg tatctccaca acctggtgta
    16801 cataaagata cacttgtaat ttgtggatct acatcacttg aagcagttgt tacttgtaca
    16861 tctaaatcaa aaaggttttt tacgttattc atttttcatt cccccagaaa gtttttatta
    16921 agaattacat cttttccatt tcattcttat aaagctctat tactaattaa cagcagaagc
    16981 tgttccaact acctgtatct ccacaacctg gtgtacataa agatacactt gtaatttgtg
    17041 gatctacatc acttgaagca gttgttactt gtacatctaa atcaaaaagg ttttttacat
    17101 tattcatttt tcattccccc agaaagtttt tattaagacg ctatgtctta tacatttaat
    17161 ttaccagacg cttttttata aagaatccgt atataccgca ataagatttt gtaaatttcc
    17221 gcatatgcaa aaaaatacat aaaagtatag tattgaaaaa taaatagttc taatgtacat
    17281 ttttacttat agtagtttaa taaccatttt ctagaaagag ggtttttctt atgactaaaa
    17341 cactatggaa ttttttaatg gagatgaaaa aaaataatct tacctttgaa aattatgagt
    17401 tatgtccatc tttgaatacc ctgtcacctg aagaaaaagt tgtattaaat gaatatgcaa
    17461 gaagtttagt tttagaaaac gaggttggaa atgaatgggt ttagaagcga tttaattgat
    17521 catattaacc agcatctttc tagctataag caaagtggaa gagcagaagt agaccttctt
    17581 gctctaaagc acctctctaa aagaggaaaa ttattaaacc aagaactttc aggattctca
    17641 tggggagaac tataccttac tctctcttat tttttaaaaa gaagaaaaat gacagaagaa
    17701 gatttcgaaa aagcttttgg tattgaatgt atattcttat ctgccgacat agtagatgat
    17761 atatgtgatc ttgatgatcc gaatcttcca acctttcaaa atgaagatcg atatcttata
    17821 ctcatttctc aatatctact ggcaaaaggc ttcttctatc tcagacctgt ctcagactct
    17881 tatgaagaca attgcctctt tagcctcata atggattcag gatgtggaga atggaaagac
    17941 ctccactttc gtttctctat aaataaaaga gttataccta ctgaagagga gtattttaaa
    18001 ctgattaaac aaaaatccgg taaattaaca gagataattt ctcaagctat cgatccttca
    18061 caacttatat taaaaaaaat cacttattat ataggcatag ctggacaatt gagaaatgat
    18121 gctgcagacg tgctaaatga caaaaaaagt gatcttcgag atttaaaagc gtatctgcct
    18181 tttttaaaag cttatgagta cagttgtgaa gtacaagatg aattctttca taagttaaaa
    18241 gatgaagaaa tcatgacctc tcctttaaaa agacagttga taagagaata catagaacaa
    18301 tctggctcta tcgattattg tcatatctta tccaggtttt actatatgag ggcatttaag
    18361 cttttagagg aacattttaa gctttcaaag aaagaaatga actacttcaa atctttattt
    18421 ctacaaagga gtcaacagca tgaacaagca taatttatta atttgtttgc ctttaggcac
    18481 tttgtacatc atcattttta tggcgaatgg ttattattta tatctaagcg attttagaag
    18541 atttgtggat tcggcaactt taaattcttt ttatgtaaca agtgttatta gtttgatatt
    18601 ttttagcatc ggattattta gcttttttaa gaaacaaaaa tccatcgtga taaaaaattt
    18661 cttcttatta acatctgtct ctggtattgc tatttctact tctgttttgt ccagtcagga
    18721 tataccagtt tttaaaacta tagagatcat tagtgtattt atgctctctt acttattact
    18781 aagtttcttc gcccacttcc cagtttcgac taaacctaat tatgtgaaaa ttataatttt
    18841 ttcatcatta cttttctcaa ccctgtcatc tgtagtgtac ttaatttgca attaccttgg
    18901 ttatgtagag cattctaaat ttttttacat atacagagtt ttattaatcg gtaacttgtt
    18961 ctttagtatt gtgggctgta tttttcttat ctctttacat ctaaaaacta attcattaaa
    19021 agtaagaaat cagttatata tcttgatctt tggaattgtt tttagctttg gtccactttt
    19081 tttattcaat ttaatacctg gaatgatttt tggagaatct caaatacctt ttgtctattg
    19141 tttacccagc attatagtct tcccactgac aacttcttac ttattagtaa agcatgaaat
    19201 tattgaagtt gaattggaaa tttctaagtg gattaatata ttgatttatt acatacttaa
    19261 ctttttgctt tttagtattt taattaaaca atttatgcac ctttctaata gagaattatt
    19321 tgtcatatgt agcgttggcc ttttatctgc atgggcatct attttccttt ataaaatagg
    19381 tattaacact tttatacaaa agaagacaaa aaatagagag aacacggacc tgaatgaaat
    19441 tgaacttttc caaacattgt ctaaagaaaa acatgctaaa aatcttgcaa aaattatagg
    19501 aaaagtcatt catcagaagt tcgatatcaa tggtttatgc attgtgtgga attctaataa
    19561 tatatatcat tcattacatg agacgggcat ttttcaaacc atgaatcaat ttaactttct
    19621 taatgaaata aacaaacttg aaaaagatat acttcttgtt gaagatcaaa cccctagcat
    19681 acatatgcat tttgaaaaat atcacttaat ctgttttcca atcgcaataa accaattagt
    19741 tcaaggtgtt attgttatag gtgaaaaaaa caaccatact ctcttccaag ggaaagagtt
    19801 cattgagctt aaagaactaa tatgtgaatc agcagatata ctttcaagtg cagctattct
    19861 caatattaat gacaaacaaa tacgtcgaac aaagacaaga gttcagaact ggaaccaatt
    19921 taatcaccaa gtcattcagt ctctagaaaa agagaggaaa agattgtcca ttttcttaca
    19981 cgatgaaatc cttcaaagtc ttattttgca attgaatgaa gttagaataa tgcaaacaaa
    20041 aaggaatttc tcagtaacat tactagacga aatggatgat cagcttgaag gaatgattta
    20101 taacattcga aagatgtgtc atgacctcca ccctatcatc gtggaggatt tgggtctaga
    20161 gccaagttta cagtctttaa aacgagaatt tgaactaaat tatagtatct taattcatgt
    20221 tcaatttaat tgtgagttca aaatcatttc taaaaatcat gaaatacaag tttatcgaat
    20281 aataaaagag ctgttaaata atgctgttaa acattcaaaa ggtaaaaaca ttaaggttct
    20341 tattttagaa gagaatggtt tctaccagtg cagcgtaaaa gatgatggca taggatttga
    20401 tgtcccagac aatttctttg attttagtaa aggtaaccac cttggtttac taactattca
    20461 tcgtcaaatt gctgaattaa atgggagtat gagaatttct tctgataaag gacaaggtac
    20521 ttttgttaca tttactattc cattggactg ggaggataaa aatgagtata cgtacgctac
    20581 tagtggatga tcatttactc gtaatgttag gaatcagaag attactcgaa agcgaagaag
    20641 acattgagat tatagataca gtcaatgatc cctcgtcttt aatagaagtt gtagcaacta
    20701 catcccctga tgtagtcgtt acagatgttc gtatgaaaga atttaacgga attgagttaa
    20761 caaaagaact tttgtctaaa tttccagaaa taaaagttgt cattttatca ggctatgatc
    20821 acgaggaata ctacaatgca gcatttaaag caggagctag tgcgtatatt acaaaagaaa
    20881 gatctgcttt cgatttagca aatgctatcc gtcaaagtaa tatgggctat atactattct
    20941 ctaaaaacca gattagcacg aaggactttg aaacccttac ttctgcggaa caaaagatac
    21001 ttcttttaat ttccaaagat aagacgaatt atgaaattag tatggatctt tcaattagta
    21061 aaagaacagt agaatatcat atttcttcta ttattagaaa gttagatgta gattcacgag
    21121 taggagcagt agtaaaaggc attaaaaaag ggttgattga agatttttaa aatttagaaa
    21181 tagataaaat agcagaaaaa gatatataaa taaattcaaa actagatatt tctatatcgt
    21241 aagtgtgcac gatgaaagat ttatcagatg gaatacagtt aaaggtgagc ttaatgaaga
    21301 tatagtagat gacaattgcc ttgcctaact aaaagaagaa gataaataat tcattagaaa
    21361 aatagaaaaa atccctggtg cgttaggggg agcttttctg ttacacatat cttatttaaa
    21421 gaacaaactc ctcaagtcat cttgaggagt ttgttccaat taataataat ttatttattt
    21481 attgatgcca tctcttgtct acatacttct tgaaaattta gatttagtta ttttttaact
    21541 cttgttacac taaaaagttt ttctccataa ttaactttac taataccaac tcttgcaagt
    21601 ccacccacaa tagcaggaag gatccatcct gaccctattt catacatagg aaaatataga
    21661 agggaataac ttattaaaat gtgtagaaca tgcacttata agtcctacac tgtttgtttt
    21721 atttaataat gacaaacggt gtcttttact tcttatggta tacagaccta tcctctactt
    21781 accttttaag aaattgtttt attaaagaca accaaatata agatttataa acattcaatg
    21841 ttattatctt tttaaaaata tatatttaac tgaaaatata aaagaaatgt attctataca
    21901 aaaaagtaaa tatataaact tctttataaa aaataaagtt ttaatattta ctctttgtaa
    21961 cgacaaatac gaagtttttc tataactctt gtgagactaa aaaggtacac ctatttagac
    22021 agttaaaaac ctaatgacaa cgcgtctatt aactctcaaa actaaacctt tttaaaccca
    22081 taaaaaataa tataccttat tatacgtttt gtcatggatg ggtaccgtca catgcccatc
    22141 atgtcacttt gacctataaa ttgcacttat tttaagtatt attttgcaca tttaacttta
    22201 atacccggct accttcacat gaaaagatta gtataatgta ttgagctctc gttcttcgtt
    22261 agcttaacga agaggccttg attttttctt gtttgagatt attatttgct tttcgttttt
    22321 agacaaaatc ctgtctgcaa ccaatcgctg ctgctttttt caacccgtct tgtcctctct
    22381 tcatatctgt ctatgaacgg ggcgggaagg ctgccataaa gaaagaacga aagccgcgtt
    22441 ttccgcgcag cttccgtccc gatcttccgg ataactaact caaataccga gttcggataa
    22501 cccccatgtg atgaatctcg tgtcctgcaa tgccgtacgc gagggcacgc gccgtaatgc
    22561 ttgcgttgtt ggctgtgcct ttgcgggacc acgcctccgc cggtaacccg cgcagcagtg
    22621 tgatcgtcga ttgccgtaca gcccggtagt cttcagccaa ctgcgcggtt gaccagcatc
    22681 cgaaaggagg catgaacaat tcctggtcga aaccggacag aggcgtctgg tcccctcttg
    22741 cgaaccggag caggcggtag gtcatgacgc gttctccgtc tgcgatgtgg cccacgactt
    22801 ctttcagtgt ccattttcct tccgcatacc gatacgcgcc atggctttcg gtcaacgatg
    22861 ccagcagttc tgtcatttgc ttttcctggg agagcagaat gtcgatgatg ttgccatccg
    22921 gcaccaaccg gatatactct ccgatggccc aggcatattc ttcttctgac ggtctttgat
    22981 tcatgcgtaa tcacctctct atgaagttat agaaaattaa aatgctcttt ccaatgctct
    23041 accgcgattt ttttgcgaat ttcgtaattt cagcatgtat aatgaattcg cgaaaggata
    23101 aaactttcct tccaatcatt gagtgtaagc aaccacttag ttggtcggtg gccacgctaa
    23161 acttcccttt aacttaataa taatcatctc aattttttat aatttccata ataagttatt
    23221 caatataatg gcccgattgt tgaatatgca caaaacccgg ttctggtgca aaggttgaag
    23281 ctatataaaa gaggtttata aattcctata ggatttgttc ttatgcagct attacgaata
    23341 gttgatgaat gaaacttatt tgattttgga cagacttcac ctcttgataa acctgtttct
    23401 ttttcatcat atgcatgacc tctattccag aaataatggc ttttgctgta cgaaacgttt
    23461 ttaagcctaa catcgtagaa aggcgcttct taataaacct gtgatcctgc tctacaatat
    23521 tatttagata tttaatttgt cttatttgga tgccttcagg catctttttt tcctttttta
    23581 gctcctggat agcaatggga taagcaggat ttttatctac tgtaatcgta tgaggtatcg
    23641 aaacgtgcga aaaagccaag gctttcttaa aaaagcgctt ggctgcttgt ttatttcttg
    23701 ctttacttag ataaaaatca atcgtatttc cctccgaatc aacggcacga tagagataca
    23761 tccattgtcc ttttactttt acataggtct catcaacccg ccaagaatcg ttcgttggct
    23821 taagatggcg tcgtactcgc tcatttaatt caggaccata ttgatgaacc caacgcataa
    23881 tcgttgtatg agcaatacat aatccacgtt cctccatcat ttctatcaag tcacgaaaac
    23941 ttaaattgta ccgtaggtaa catcttacat ttaacaaaat aagatcaggc tgataatgtt
    24001 tccatttgaa tacattttcc ttttccatac cgatcacaca cctttttaag aataatagta
    24061 tcagtatatc caagttttag agatggctta taagtaaatt gaagtatttg caccagaacc
    24121 agactttttc tattttgttt tctttcaaat aattctcaat ctccttattt ttttctgaat
    24181 attttaacat ttttataaat atatgtcttt gaaatggtat aatatagaga acgtcagttc
    24241 tggaggctta gtatgcaaat taaaaaagtt tatatttatg tatttaacac aatgtcagat
    24301 tgggagtatg gatatttaat tgctgaacta aattcaggaa gatatttcag acaaggttta
    24361 gcccctttaa aagtaatgac agtaggagtt aataaagaaa ttattaaaac aatggggggg
    24421 ctgagtatac agccggatag ttctcttgat gagtgcactc ttttggataa agatctttta
    24481 attctaccgg gaggaaatac atggagtgag gagattcatc aacctatatt gaaaaaagtt
    24541 ggggaagttt tagagcttgg tactattgta gctgcaattt gtggtgctac tgatgccctt
    24601 gcaaatagtg gatacttaga ttctagaaag catacgctta ataacttaga atatacaaaa
    24661 atggtctgtc ccaactataa aggggagaag ttgtatgagg ttggacctgt agtatccgat
    24721 aataacatga ttactgcttc aggagtagca cctctagaat tcgcgaggga cgtattaaaa
    24781 aaattagatg tattcgcatc aaatacatta gattcatggt ataggttaaa taaaactcag
    24841 aagtccgaat acttttttca gttaatgagc tcaatataga tccctaatta tatacaaggt
    24901 ggattacaat aattttcttt tttatttttg tagataccta taatccgttt tatgttaact
    24961 aaagatgtat atcttacaca ccttaaaaat acaaaaaaac ctatctcttt ccaatccaaa
    25021 gaggtaggtt ttttctgctc tattgctgta aggattttcg ctgatgcctc acagcgtctc
    25081 gtgtagtttg ctcagaacag aaagattcat gtaaaaaaga aaaacttagt gttttcttat
    25141 atccaatatc ttaataacgt tgtttaaatg cttttctgat tcttctaaac gtttttgagt
    25201 atttactaaa gatttttgaa cagataaaac agagggagct ttgatatttt tggcttctgt
    25261 gcatactaga tgacctatac tgtcctgcca ttggatcgta catttgaaat tcataaataa
    25321 cttgttgctt gtttgcaaaa taagatattg ggttacaggg taagaatttg taatctgtga
    25381 cagcattaat attgctttat ttcggtcttc tttataaata atattccata tgctagaggt
    25441 agattgaaaa tatgaatgag ttatatttga agaatttaga attgtaccat cttgcctaat
    25501 ttgaaaataa ggaacaggaa tccatttagc tatattactc atatccatgt tctaactcct
    25561 ttaaattaat gaattttttc acttgggaca atatgtttct agagcatgac catggtaaat
    25621 taagatgtat ataatataca tcttaattat caaaaaaatt accctatcta aaggtattcc
    25681 gaaaattttt ttatgttaac taaagttgta gacgatattc atttcatatg attagctttt
    25741 tataaacaat aaaatataaa ccgccatgta tattaatcta taaatacggt tagactagta
    25801 acgtattccc cctattccgt tatagttgaa aaccctttgc tattttatag caaagggttc
    25861 tttttttgcc cttgataata ctcataatga aattagctca ggtagcaaat gtgaatatca
    25921 tgacataagg ttaatgaaaa atgaaaatag ctgttcctat aaaatatgtt gttaatttag
    25981 atgtataaga gattactagt tgggggacaa taaaaaatag aaacttacat ataggaggta
    26041 aaactagtga gcgaacataa aaacattttt tctacgtttg ttaatgaaaa tcaatttgac
    26101 ttacattcat accttactta tttattcatc aatgaatgcc aggaaggtgt agtaaacgaa
    26161 ttagaacaga aacatataaa ccaataaatt tataaataaa aatgtgaaat gagagggtaa
    26221 atcatagtga atgaaaaaat ggtgtagacg actttatctt tctgggaaga aggaataagt
    26281 cgtctattat acttgcctaa tcaggtacgc ataaaacaag gtatcagtaa aaattctcct
    26341 tctagttcca taacatatca taataaaaaa gccgaaaagg taagcctcgg ctttttgaat
    26401 cacgcggtat ctatataatg ttgtatatca ttagtaatga accttaatct t
//
