LOCUS       NZ_CP046588            22898 bp    DNA     circular CON 12-MAY-2024
DEFINITION  Stenotrophomonas sp. SXG-1 chromosome, complete genome.
ACCESSION   NZ_CP046588
VERSION     NZ_CP046588.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas sp. SXG-1
  ORGANISM  Stenotrophomonas sp. SXG-1
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas.
REFERENCE   1  (bases 1 to 4534602)
  AUTHORS   Zhang,X., Shang,B., Li,X., Li,Z. and Tao,S.
  TITLE     Complete genome sequence data of multidrug-resistant
            Stenotrophomonas sp. strain SXG-1
  JOURNAL   J Glob Antimicrob Resist 22, 206-209 (2020)
   PUBMED   32311503
REFERENCE   2  (bases 1 to 4534602)
  AUTHORS   Shang,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-DEC-2019) Guizhou Fisheries Research Institute,
            Guizhou Academy of Agricultural Sciences, No. 2448 South Section
            Huaxi Avenue, Huaxi District, Guiyang, Guiyang 550025, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 500.0x
            Sequencing Technology             :: Illumina HiSeq; Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014083965.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 12:38:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,125
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 4,012
            CDSs (with protein)               :: 4,012
            Genes (RNA)                       :: 91
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 22
            CDSs (without protein)            :: 22
            Pseudo Genes (ambiguous residues) :: 0 of 22
            Pseudo Genes (frameshifted)       :: 8 of 22
            Pseudo Genes (incomplete)         :: 13 of 22
            Pseudo Genes (internal stop)      :: 5 of 22
            Pseudo Genes (multiple problems)  :: 3 of 22
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:22:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1739540
            Orig. end                         :: 1762438
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP046588.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22898
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="3"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22898
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22898
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12898](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12898
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            76..591
                     /locus_tag="GOC52_RS08045"
     CDS             76..591
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646745.1"
                     /locus_tag="GOC52_RS08045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_010484296.1"
                     /transl_table=11
                     /translation="MRQSVSTVRVLSYALLAVAVAAGTTGCFKRGVKGDYALAPEMRPL
                     EVPPDLNLPTTTGDNKVPTLASATKPAAPAAAAPAVGNTGFTIAGGKDEAFAKVGTALE
                     GVEGVTIASRAQLLGSYDVAYEGSNFLVRVVAVDAGAYISAVDPRGLPATAEAPVKLIA
                     ALKAKLAQ"
     gene            complement(788..1111)
                     /gene="fdxA"
                     /locus_tag="GOC52_RS08050"
     CDS             complement(788..1111)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Ferredoxin"
                     /gene="fdxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005994928.1"
                     /locus_tag="GOC52_RS08050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferredoxin FdxA"
                     /protein_id="WP_004153066.1"
                     /transl_table=11
                     /translation="MPFVVTENCIKCKHTDCVEVCPVDCFHEGPNFLVIDPDECIDCTL
                     CEPECPVNAIFPEDDVPAGQESFVALNAELAKEWPVLTVRKDPPADAGEWDGKPDKLKL
                     LER"
     gene            1304..2728
                     /locus_tag="GOC52_RS08055"
     CDS             1304..2728
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019661180.1"
                     /locus_tag="GOC52_RS08055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar porter family MFS transporter"
                     /protein_id="WP_010484300.1"
                     /transl_table=11
                     /translation="MSPAQPNIASHGGENTAFIVLISCVATLGGFLFGFDSGVINGTVD
                     GLRQAFNSSEAALGFEVASMLLGCAIGAFLAGWLGDRLGRRGVLIASALMFLVSALGAG
                     AAHASWLFIAARVLGGFAVGAASVMSPAYIAEVASARYRGRLATVQQMAIICGLFAAFL
                     SNYLLARAAGASTEPLWLGHEAWRWMFWMQALPSGLFLLLLLVIPESPRFLVVKGRQQQ
                     ARAVLSRLYGEAAAAAKQAEIEASLAQDQHKPRFADLRDTVSGKLRPILWVGIGLAMFQ
                     QLVGINVVFYYGAVLWQAVGFSESDALLINVLSGALSIGACLLTVLLIDRIGRKPLLWI
                     GSVGMSVALVLMVVAFASGSLADGRLQLSDGMGRLALVAANVYVVFFNMSWGPVMWVML
                     GEMFPNQIRGPALAVAGAAQWTSNFAITVTFPMLLAGIGLAGAYGIYTVAAILSIVFVV
                     RYVRETKGKELEQMEG"
     CDS             2832..3053
                     /gene="allorf_1742372_1742593"
                     /locus_tag="allorf_1742372_1742593"
                     /protein_id="allorf_1742372_1742593"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAPSMAPTVLERAARPLLTVSWCVRMRRSAGRLLPQLAGNRPESV
                     GSPRAGPLAPRMAPSSPHGWVHGVSCPG"
     CDS_motif       2832..2972
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MAPSMAPTVLERAARPLLTVSWCVRMRRSAGRLLPQLAGNRPESVGS"
                     /locus_tag="allorf_1742372_1742593_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       2973..3053
                     /prepeptide="core"
                     /locus_tag="allorf_1742372_1742593_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="2567.9"
                     /monoisotopic_mass="2566.3"
                     /core_sequence="PRAGPLAPRMAPSSPHGWVHGVSCPG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAPSMAPTVLERAARPLLTVSWCVRMRRSAGRLLPQLAGNR
                     PESVGS"
                     /leader_location="[2831:2972](+)"
                     /alternative_weights="2586.0"
                     /alternative_weights="2604.0"
     tRNA            complement(3178..3252)
                     /anticodon=(pos:complement(1742757..1742759),aa:Glu,
                     seq:ctc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="GOC52_RS08060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Glu"
     gene            complement(3178..3252)
                     /locus_tag="GOC52_RS08060"
     misc_feature    3196..3211
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.79"
                     /tool="antismash"
     gene            3305..4678
                     /gene="pcnB"
                     /locus_tag="GOC52_RS08065"
     CDS             3305..4678
                     /EC_number="2.7.7.19"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:1990817 - poly(A) RNA polymerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006378 - mRNA polyadenylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pcnB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017116093.1"
                     /locus_tag="GOC52_RS08065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="WP_029550838.1"
                     /transl_table=11
                     /translation="MGNPETSTGSANIISSATSPFSLRVIPRDQHTISRKDISPNALRV
                     LYRLRDAGFGAYLVGGAVRDLLVNGQPKDFDVATDATPEQVKQLFRNCRLIGRRFRLAH
                     VVFGREIIEVATFRANSDDGSGDREMENGMLVRDNVYGTIEDDAIRRDFTCNALYYAIE
                     DFSVRDYTGGFEDVQARLMKLIGDPEQRYREDPVRMLRAVRLAAKLGFQIEEGTAAPIP
                     HLAGLLNEAAPARLFEEVLKLFLSGHGVASFEGLERYGLLDVLFPESAKALKSNRTGAL
                     RRMLVEGLANTDARVANDEPVSPAFLFALLLWPAFCRAQATLLKQGVAPEEAQRRAADR
                     VTVQQLSTIALPRRFSLPMQEIWLLQSRFSSRQRKRVFRTLTHPRFRAAFDFLSLRQVA
                     SSEHAVDVEFWREAQAQSGRELESSLDAMHSEDGDDESGAPRKRRRRRRRPGAAAAGE"
     gene            4682..5167
                     /gene="folK"
                     /locus_tag="GOC52_RS08070"
     CDS             4682..5167
                     /EC_number="2.7.6.3"
                     /GO_function="GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA]"
                     /GO_process="GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="folK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019338321.1"
                     /locus_tag="GOC52_RS08070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="WP_019338321.1"
                     /transl_table=11
                     /translation="MTLAWIGLGANLGDAAATVGAAIAALDGLPGTRLRQASRLYATPA
                     WGNEDQPPFVNAVASVETTLPADELLQAMLALERGFGRVRDPAVHWGPRALDLDLLLYG
                     AQVLDHPGLQVPHPYMHERAFVLVPLAEIAPDLAIPGHGRVQDAVMRVDACGIAPIG"
     gene            5202..6017
                     /gene="panB"
                     /locus_tag="GOC52_RS08075"
     CDS             5202..6017
                     /EC_number="2.1.2.11"
                     /GO_function="GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416119.1"
                     /locus_tag="GOC52_RS08075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-methyl-2-oxobutanoate hydroxymethyltransferase"
                     /protein_id="WP_019338322.1"
                     /transl_table=11
                     /translation="MSTHADSKPWTVPALAEAKRNGQKLVMLTAYDAGFARTFDANGVD
                     LILIGDSLGMVVQGHDSTLPVTVADMVYHTRAVARVLQRALLVADLPFGADATPERALD
                     ASLQLLQAGAEMVKIEGAGFKVDIIRYLVEREIPVCSHLGLTPQSVLRLGGFKIQGRGD
                     AARQLVEDARAVAAAGASIMVLECVPTPVAAEVTAAVDVPTIGIGAGPQCDGQVLVLHD
                     FLGLDSGHRRPKFVKDFLAEGGSVAGATRAYADAVRDGSFPDEQHAYAQ"
     gene            6014..6853
                     /gene="panC"
                     /locus_tag="GOC52_RS08080"
     CDS             6014..6853
                     /EC_number="6.3.2.1"
                     /GO_function="GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011259031.1"
                     /locus_tag="GOC52_RS08080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="WP_010484306.1"
                     /transl_table=11
                     /translation="MIQTFNELGALREQIAQWKREGLRVALVPTMGNLHGGHHSLVTLA
                     RQYADKVVTSIFVNPTQFGPNEDFSRYPRTPEADVAGLEQAGCDAVWLPSVEAMYPLGV
                     DKTTQMHAPGVSEVLEGASRPGHFDGVCTVVARLFLQVQPDVAVFGRKDYQQLAVIRQM
                     VAELSFPVQIVGAEIVRDEDGLAKSSRNQYLNAEQRPVATTIHRTLLGMREGYVAGHTR
                     VQIEADATAALQAAGFQVDYAVLRTPELAEPTFDGGGRVALIAARLGTTRLIDNLEF"
     misc_feature    6916..6927
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            6920..7417
                     /locus_tag="GOC52_RS08085"
     CDS             6920..7417
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010484309.1"
                     /locus_tag="GOC52_RS08085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_049453343.1"
                     /transl_table=11
                     /translation="MKAPSTDTGRLAQASILAVLAAGMLPAQLFGGLLFALEFRRTPMP
                     ALTGGGLMFVLAVCNAIAVLLPMALILQSQQRLRRAGFVLVGFGLGALAMATCAWPGEN
                     QGPWLQRLRYVDTFDVISYALQVLAAGGFGLVAGLAFHTVFRLSLEGSSGHAAPPPPGE
                     GT"
     gene            7505..7885
                     /gene="panD"
                     /locus_tag="GOC52_RS08090"
     CDS             7505..7885
                     /EC_number="4.1.1.11"
                     /GO_function="GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011036943.1"
                     /locus_tag="GOC52_RS08090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate 1-decarboxylase"
                     /protein_id="WP_005409061.1"
                     /transl_table=11
                     /translation="MHLSLLKTKIHRATVTHSELNYEGSIAIDDNLLAATGIREFEQVH
                     IWDVTNGARFSTYAIRAEAGSGVVSLNGGAARHVQVGDIIIIAAFASMTEQEADSFKPK
                     LVYVDGKNQITHTNDTIPTQAA"
     gene            7882..9396
                     /gene="pgi"
                     /locus_tag="GOC52_RS08095"
     CDS             7882..9396
                     /EC_number="5.3.1.9"
                     /GO_function="GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pgi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019300464.1"
                     /locus_tag="GOC52_RS08095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="WP_049453344.1"
                     /transl_table=11
                     /translation="MTTNNGFDSLHSHAQRLKGASIPSLLAAEPGRVQDLALRVGPLYV
                     NFARQKYDAAALQALLALAAERDVGGAITRLFRGEQVNLTEGRAALHTALRGDVVDAPV
                     AAEAYATARTIRQRMGVLVRALEDSGVTDVVSVGIGGSDLGPRLVADALRPVSGARLRV
                     HFVSNVDGAAMQRTLATLDPARTAGILISKTFGTQETLLNGQILHDWLGGSERLYAVSA
                     NPERAAKAFAIAADRVLPMWDWVGGRYSLWSAVGFPIALAIGFERFEQLLEGAAQMDAH
                     ALDAPLERNLPVLHGLTDIWNRNVLGHATHAVMTYDQRLALLPAYLQQLVMESLGKRVQ
                     RDGQPVTTDTVPVWWGGAGTDVQHSFFQALHQGTSIVPADFIGCVHNDDPYTINHQALL
                     ANLLAQTEALANGQSSDDPHRDYPGGRPSTLILLDALTPQALGALIAMYEHAVYVQSVI
                     WNINAFDQFGVELGKQLASGLLPALQGEDVAVADPMTREILARLKG"
     CDS             9435..9551
                     /gene="allorf_1748975_1749091"
                     /locus_tag="allorf_1748975_1749091"
                     /protein_id="allorf_1748975_1749091"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSLRLPSIRSRMKAARPLIPSCFRAAHAALPRACRSAA"
     CDS_motif       9435..9479
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSLRLPSIRSRMKAA"
                     /locus_tag="allorf_1748975_1749091_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9480..9551
                     /prepeptide="core"
                     /locus_tag="allorf_1748975_1749091_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.80"
                     /molecular_weight="2399.8"
                     /monoisotopic_mass="2398.3"
                     /core_sequence="RPLIPSCFRAAHAALPRACRSAA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSLRLPSIRSRMKAA"
                     /leader_location="[9434:9479](+)"
     misc_feature    complement(9542..9558)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 21.78"
                     /tool="antismash"
     misc_feature    9705..9723
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 27.95"
                     /tool="antismash"
     gene            9712..9918
                     /locus_tag="GOC52_RS08100"
     CDS             9712..9918
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268305.1"
                     /locus_tag="GOC52_RS08100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6229 family protein"
                     /protein_id="WP_043402549.1"
                     /transl_table=11
                     /translation="MDLNDDVVSGWLNGADDVDGCANPAGSLFIYGAAATEAALTGASD
                     TMITGGTNECTTTVSVINHCLCC"
     CDS_motif       9712..9864
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MDLNDDVVSGWLNGADDVDGCANPAGSLFIYGAAATEAALTGASDTMITGG"
                     /locus_tag="GOC52_RS08100_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9865..9918
                     /prepeptide="core"
                     /locus_tag="GOC52_RS08100_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.40"
                     /molecular_weight="1751.0"
                     /monoisotopic_mass="1749.8"
                     /core_sequence="TNECTTTVSVINHCLCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDLNDDVVSGWLNGADDVDGCANPAGSLFIYGAAATEAALT
                     GASDTMITGG"
                     /leader_location="[9711:9864](+)"
                     /alternative_weights="1769.0"
     gene            10001..12898
                     /locus_tag="GOC52_RS08105"
     CDS             10001..12898
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019338325.1"
                     /locus_tag="GOC52_RS08105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_053442821.1"
                     /sec_met_domain="DUF4135 (E-value: 2e-78, bitscore: 262.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.1e-34, bitscore:
                     115.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASPAAAAFARITEHFLAHARAALATGLHDPAIALQPGERELLH
                     AQGDAALREHAQLKLNRVLLLELHAAARSGDIGPLGSAGALDEFVALATSEGFRTHLQR
                     RYPVLLPRLTRMLEGQCAAVVELAVRIGSDRAALAGLLGAPAGTLHAVALGRGDLHGGG
                     RTVARLQFEGGTVMYKPRSLRIDATLDGLLCTLFGDGPDRVCVPKVIDRGSHGWAAFAA
                     HRYCADDVELRAYYRGLGHWLAILRLVGGTDIHLENLIAVGPVPVVIDAESVFSRVIEI
                     EPSGLGDAYDTAVKLMRNSVLRTGIVPFRTAGLGMEGVDLSAAGALPGEQPRVQVPVIV
                     EGGTEPARLGMVEAEVSVAQNHPSAQPDVSLYWDHISEGFIDASGRLRALDAKGELMPL
                     LAAFEGCQVRDVRRPTMAYAELGRMLWHPASLHNEAQAVERAIDLLVRNAAVSPAAPSD
                     LDTVRSEVDDLRHGDIPIFTSQLDAARIRSIADNWRAMRIDLEDVTIRSTLVATDLNQH
                     ALARAEARSGYSYAAQHPRADDLDARRRTLAARAVESLLRLAVHGEDGSMTWITPEVTR
                     TGWTVQPVQPDLYFGLGGIAFALAAYHREVEQGRADPVAGLGPAIDGALAVFQTMCEQH
                     PAEIDGGFVGTGSQIWTLLALHDLLQRPALLVLAERCAEAAERRGFQEATKFELIDGVS
                     GMILPLLSLAAATGNARWLELAAAAGRRMQEAAIVDADGARWPTPQFREPIGGFGHGAM
                     GMGWALARLARSDAGSVPERAAWRQLAEGAFAFQAALFEPHTGHWRDIHLQDGQKNFPT
                     WCHGSVGIGLAAADLYARTGDPAQLRDMRRAVADARGKWGFSHTLCHGDVSTRELLVLA
                     AALDPEGCPYPQDEAAIEIVSSIEEHQGMVGGLTRAAFTPGLMIGLAGAIYGFLRMHPA
                     CALPSPLLQETTVARVDAPASRSITAQDRAVLAEV"
     gene            complement(12920..13483)
                     /locus_tag="GOC52_RS08110"
     CDS             complement(12920..13483)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005409063.1"
                     /locus_tag="GOC52_RS08110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_054171466.1"
                     /transl_table=11
                     /translation="MSTSTLGLLVDDDELYLRTLQRSLARKGLETQTAQDAASALALAR
                     QHPPAFALIDLKLGSDSGLALIQPLRALRADMRILLVTGYASIATAVEAIKLGADDYLP
                     KPATVPMILRALGEEDDGPADDGEMEVPDAMTPISRLQWEHIQQAMHETGGNVSAAARL
                     LGMHRRSLQRKLAKRPSPERDPSR"
     gene            complement(13480..14706)
                     /locus_tag="GOC52_RS08115"
     CDS             complement(13480..14706)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019661188.1"
                     /locus_tag="GOC52_RS08115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_191851108.1"
                     /transl_table=11
                     /translation="MTGPDAPFLRTLCSLRWLAVGGQAATILVASWVLGLPLPQLPLWA
                     GVAVLTLFNIYTQLRPEAADTAPLTAFGHILVDVIILTWMVGWSGGMANPFSSLFLILI
                     ALAAFALPLRWALAVALACLLGYAASGIFGQPLPDGYFRAQDLNRWGVVANFLISAAVV
                     LAFSTRLALALRQRELELSALRERFARNEGIVALATHAASVAHELNTPLATMTLLADDV
                     AERSEEPEVREDMETLRELLVQCRERVLALAAPASADAPGRSHSSAQQVLEQWRLVRPT
                     IDLHRNDDAPLRLPLDPGVGHLLMVLLNNAADAGEQAGRPRVDLDLRIEGDDLIGEVRD
                     YGHGFDARAAVLPGKLFGSSKSEGMGVGLALSHATIERLDGEMWMRPAQGAGSRVGFRL
                     PLALREETP"
     misc_feature    14776..14794
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.46"
                     /tool="antismash"
     gene            14821..16086
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="GOC52_RS08120"
     CDS             14821..16086
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019300453.1"
                     /locus_tag="GOC52_RS08120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_191851110.1"
                     /transl_table=11
                     /translation="MHDAVTRPTPPSDATSWPRRQTHAVQIGGVTVGGGKPVVVQSMTN
                     TDTSDVASSVKQVAELWRAGSEMVRLTVNTVEAAAAIPRIVDKLAMMGIDVPLIGDFHY
                     NGHQLLTAEPACAEALAKYRINPGNVGFGKKKDLQFAQLIEFAIRYNKPVRIGANWGSL
                     DQALAAKLMDENNLREQPWDAGRVLREALIRSALDSAEQAVELGLPRDRIVLSAKVSGV
                     QELIAVYRDLAQRSDFALHLGLTEAGIGSKGIVASSAALGVLLQEGIGDTIRISLTPEP
                     GQSRTQEVIVAQELLQTTGQRAFTPLVTACPGCGRTTSEFFQELAKVVQNHVREKMPLW
                     KIHHPGAENMTLAVMGCIVNGPGESRHANIGISLPGTGETPAAPVFVDGEKKVTLRGDN
                     IAQEFVALIDDYVEHTYVRSAG"
     gene            16067..16816
                     /locus_tag="GOC52_RS08125"
     CDS             16067..16816
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646755.1"
                     /locus_tag="GOC52_RS08125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_058980273.1"
                     /transl_table=11
                     /translation="MSEAPDKPAILAAPESASGFRHWMARNAWRLVLLFGGVLLPLAGF
                     VALADEVHEFESFHFDAPLLWQMHGLHSPLLDRFFVLISKLGYEWFLIPADVLIIGVLL
                     GYRRWREATFVAVSFVGSALLNMGSKHFFQRQRPSLWESIAPESTFSFPSGHAMGSMTL
                     AVTLVLLAWNTRWRWPVLLLAPAFSLLVSVSRVYLGVHYPSDILAGWCAALVWVVGCYL
                     VMFSRRHPWRHHGTRPAKASEASSQGD"
     gene            17017..17664
                     /locus_tag="GOC52_RS08130"
     CDS             17017..17664
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011408972.1"
                     /locus_tag="GOC52_RS08130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator"
                     /protein_id="WP_021202017.1"
                     /transl_table=11
                     /translation="MTIRVYLVDDHALVRTGMKMILSGEADIEVVGEAETGEDALREVR
                     QLLPDVVLCDLHLPGVSGMEVTERIVRSHRNTRVVIVSVLEDGPLPKRLLEAGAAGYIG
                     KGCDAQELLRAVRDVAGGRRYLGTSIAQNLALSTVEGNGSPFDSLSPRELEVALLLTQG
                     LRQEDIARRLSLSAKTVNTHKARLFEKMGIHDNIALARMASQYGLVDPARPL"
     gene            complement(17960..18619)
                     /gene="eda"
                     /locus_tag="GOC52_RS08135"
     CDS             complement(17960..18619)
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /GO_function="GO:0008675 -
                     2-dehydro-3-deoxy-phosphogluconate aldolase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008700 - 4-hydroxy-2-oxoglutarate
                     aldolase activity [Evidence IEA]"
                     /GO_process="GO:0009084 - glutamine family amino acid
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /gene="eda"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265926.1"
                     /locus_tag="GOC52_RS08135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="WP_043402561.1"
                     /transl_table=11
                     /translation="MGIEQHQVKAAELLHAAGILPVVTIHTLDQARAVSAALLEGGLPA
                     IELTLRTPVAMEALAMLKRELPDVVVGAGTVLTVEQMQQSIDAGADFLVTPGTPPALAD
                     ALAAAPLPVVPGAATPTELLSLYARGFRVCKLFPATAVGGLAMIKGLAGPVADLKLCPT
                     GGITENTAAEYLEQKNVVCIGGSWMVPGNWIANGEWDKVRASATDAAKIIKRVRGH"
     misc_feature    complement(18587..18596)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     misc_feature    complement(18814..18829)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.9"
                     /tool="antismash"
     gene            complement(18822..20738)
                     /gene="edd"
                     /locus_tag="GOC52_RS08140"
     CDS             complement(18822..20738)
                     /EC_number="4.2.1.12"
                     /GO_function="GO:0004456 - phosphogluconate dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /gene="edd"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015472018.1"
                     /locus_tag="GOC52_RS08140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphogluconate dehydratase"
                     /protein_id="WP_191851112.1"
                     /transl_table=11
                     /translation="MSLHPQLQAITERVIRRSAASRAAYLAAIDASLREGPFRSRLSCG
                     NLAHGFAACGGTDKSRLRGGVTPNLGIITAYNDMLSAHQPFETYPEQIREIARELGATA
                     QVAGGVPAMCDGVTQGRGGMELSLFSRDVIAQATAIGLSHDMFDTTVYLGVCDKIVPGL
                     LIGALAFGHLPAVFVPAGPMTPGIPNKQKAEVRERYAAGEATREELLEAESASYHGAGT
                     CTFYGTANSNQVLLEAMGVQLPGASFVNPGTPLRDALTREATERALHITALGDDFRPLG
                     RIIDERAIINAVIALMATGGSTNHTIHWIAVARAAGIVLTWDDFDELSQLIPLLARVYP
                     NGDADVNRFAAAGGPAFVFGELIKAGLMHGDLVSVARGGMADYAREPQLRDSQLVYLPG
                     LERSADDEVVRGVDNPFEHQGGLRLLRGNLGKSLIKLSAVKPQYRTIEAPAVVVDAPQV
                     LNKLHAGGLLPQDFVAVVRYQGPRANGMPELHSLAPLLGLLQNQGRRVALVTDGRLSGA
                     SGKIPAAIHVTPEAARGGPLAKVREGDMIRLDGEAGTLEVLVDAAEWAARPLAPNTAPA
                     AHDLGRNLFAINRRVVGPADQGAISISCGPAAADGGPWDYDAEYELGHDAAAAAAPHEA
                     KDA"
     misc_feature    20697..20710
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            complement(20797..21519)
                     /gene="pgl"
                     /locus_tag="GOC52_RS08145"
     CDS             complement(20797..21519)
                     /EC_number="3.1.1.31"
                     /GO_function="GO:0017057 - 6-phosphogluconolactonase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pgl"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479767.1"
                     /locus_tag="GOC52_RS08145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="6-phosphogluconolactonase"
                     /protein_id="WP_191851114.1"
                     /transl_table=11
                     /translation="MSPTFHDDRIEFISHGDADGWIEAVAAEMAQTLNHDINEVGRARI
                     LLSGGTTPAPVYQALAELDVHWDRVEVSLADERWLSPQDRDSNAWLVREHLLKRAEGAH
                     FDPLVRIGKPLPECVYTANLQAQHSQPPSLVALGMGNDGHTASLFPGSKDLVRALESTL
                     PYAALDATGCPGANQWPLRITLTPHGLGQCRQRLLLLRGKQKLQVLRQALDSNDAQQYP
                     ILNAINLDGARLRVHWAD"
     gene            complement(21516..22523)
                     /gene="glk"
                     /locus_tag="GOC52_RS08150"
     CDS             complement(21516..22523)
                     /EC_number="2.7.1.2"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416128.1"
                     /locus_tag="GOC52_RS08150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glucokinase"
                     /protein_id="WP_010484331.1"
                     /transl_table=11
                     /translation="MSASSQPVLVADIGGTNARFALADTSQDAPLQKDSIREYAVAEFP
                     SLGDAARHHLEQIGATASRGVFAVAGRVDGDEARITNHPWVISRSRTAAMLGFDELHLI
                     NDFAAQAMAISLLQPDDVVQVGGAAWVPGKPGQPRNYAVIGPGTGLGVGGLILRHGRCY
                     PLETEGGHVSFPPGTPEEIRILEILSEQFGRVSNERLICGPGLVNIHRAVCEMAGIDPG
                     QLQPVDVTARALHGDPQAMRTVDVFCAVFGAIAGDLVLTQGAWDGVFLTGGLTPKMLDS
                     LQHSGFRQRFEHKGRFSSIMARVPSLAVMHPHAGLLGAAAYAADAERDAPGVAA"
ORIGIN
        1 tgccggcgac atcgccgccc tcgaagccct ttccagccac tgaccttccg tcttggtctg
       61 acccaggaga ttcacatgcg tcaatccgta tccaccgtcc gcgtgctgtc ctacgccctg
      121 cttgcggtgg ccgttgccgc cggcaccacc ggctgcttca agcgtggtgt caagggcgac
      181 tacgccctgg ccccggaaat gcgtccgctg gaagtgccgc cggacctgaa cctgccgacc
      241 accaccggtg acaacaaggt gccgacgctg gcatcggcga ccaagccggc cgcgcctgcg
      301 gctgcggccc cggccgtggg caacaccggt ttcaccatcg ccggtggcaa ggacgaggct
      361 ttcgccaagg tcggcaccgc gctggaaggc gtggaaggtg tgaccattgc cagccgcgcg
      421 cagctgctgg gctcgtatga cgtggcctac gaaggcagca acttcctggt ccgcgtggtc
      481 gccgtcgatg ctggcgccta catctccgcg gtcgacccgc gtggcctgcc ggccaccgcc
      541 gaagcgccgg tgaagctgat cgctgcgctg aaggcgaagc tggcgcagta agggctggtc
      601 gggtgggggc gggccttggt ccgcacccgc tctggtggag gccgaccttg gtcggcgctt
      661 ctgtgccaac caaggttggc acctgccgga tcgcaaggtt ggcataccgg atcttgcggt
      721 tggcgtttac cggaaaacag aaaagggcgc ccgtgggcgc ccttttcgtt gccgccgtgg
      781 gcgcttctca gcgctccagc agcttcagct tgtccggctt gccgtcccat tcgccggcat
      841 cggcgggcgg gtctttgcgc acggtcagca ccggccactc cttcgccagc tcggcgttga
      901 gggccacgaa actttcctgg ccggcaggaa catcgtcctc cgggaagatc gcgttgaccg
      961 ggcattccgg ttcgcagagg gtgcagtcga tgcactcatc cgggtcgatc accaggaagt
     1021 tggggccttc gtggaagcaa tccacggggc acacttccac gcaatcggtg tgtttgcact
     1081 tgatgcagtt ttcggtgacg acaaagggca tgggctgggg gtggatcgat tcctgaaccc
     1141 gccaattcta gaacaggttg gcccccggtg tcggtgcggg gcggaaatcg ggcgtctggc
     1201 aggcgcggcc gtggcggtca ttggcggcag ggcgaggcct gtgcgacgct gcgggtcagc
     1261 cggctgcgtc ggatggccgg accccttccc agcaggatcg tccatgtccc cagcccagcc
     1321 caacatcgcc tcccatggcg gtgagaacac tgcattcatc gtcctgatca gctgcgtggc
     1381 caccctgggt ggattcctgt tcggcttcga cagtggtgtc atcaatggca cggtcgatgg
     1441 cctgcgccag gctttcaact ccagtgaggc ggcgctcggt ttcgaggtcg cctcgatgct
     1501 gctgggctgc gcgatcggtg ccttcctggc cggctggctg ggagatcgcc tgggccgtcg
     1561 tggcgtgctg atcgcctcgg cgctgatgtt cctggtttcg gcgctgggtg ccggtgccgc
     1621 acacgcctcc tggttgttca ttgccgcacg cgtgctcggc ggcttcgcgg tgggcgcggc
     1681 cagtgtgatg tcgccggcct acattgccga ggtggcttcg gcgcgctatc gcgggcgttt
     1741 ggccacggtg cagcagatgg cgatcatctg cggcctgttc gccgccttcc tcagcaatta
     1801 cctgctggcc cgtgccgctg gggcgtcgac cgagccgcta tggctgggcc atgaggcctg
     1861 gcgctggatg ttctggatgc aggcgctgcc gtcggggctg ttcctgctgt tgttgctggt
     1921 gattccggaa agcccgcgct ttctggtcgt gaaagggcgt cagcagcagg cgagggcggt
     1981 actgtcgcgg ctgtacggcg aggccgctgc ggcggccaag caggccgaga tcgaagccag
     2041 cctggcgcag gaccagcaca agccgcgctt tgccgacctg cgcgacacgg tcagcggcaa
     2101 gctgcgcccg atcctctggg tgggcatcgg cctggccatg ttccagcagc tggtcggcat
     2161 caacgtggtg ttctactacg gcgcggtgct gtggcaggcg gtgggcttct cggaaagcga
     2221 tgcgctgctg atcaacgtgc tgtccggcgc gctgagcatc ggcgcctgtc tgctgacggt
     2281 gctgttgatc gaccgcatcg ggcgcaagcc gctgctgtgg atcggttcgg tcggcatgtc
     2341 ggtggcgctg gtgctgatgg tggttgcctt cgccagtggc agcctggccg acggtcgcct
     2401 gcagctgtcc gacggcatgg gccgactggc gctggtggca gccaacgtct acgtggtgtt
     2461 cttcaacatg tcctggggcc cggtgatgtg ggtgatgctg ggcgagatgt tccccaatca
     2521 gatccgtggt ccggcgctgg cggtggccgg cgccgcgcaa tggacctcga acttcgcgat
     2581 caccgtgacc ttcccgatgc tgctggccgg catcggcctg gccggcgcct acggcatcta
     2641 tacggtggcg gccatcctct cgatcgtctt cgtggtccgc tacgtgcgcg agaccaaggg
     2701 caaggagctg gagcagatgg aaggctgacg gcgactggct tcggttgcat tccgttggcg
     2761 cctgcctgtc cagagtgtga gggggcaggc cgccctctcc aggacacgca aaagcccatc
     2821 catggtgctc gatggcgcca tccatggcgc caacggtcct ggagagggcg gcccgccccc
     2881 tcctgacagt ttcatggtgc gtgcggatgc ggcgaagtgc tggtcggttg ttgccgcagc
     2941 tcgcgggaaa ccgtccagag tcggtggggt cacccagggc aggaccgttg gcgccaagga
     3001 tggcgccatc gagcccccat ggatgggttc acggcgtgtc ctgccctggg tgaccccacc
     3061 ggctcaagcc gattgcaggc aggcgccaaa gcgaccaagc cgatcgatgc cattgcaaac
     3121 cccggaaaac agaaaagccc acacaaggcg ggctttttcg gttcctgctg cggcgactgg
     3181 cgctccctag gggactcgaa cccctgtttt agccttgaga gggccacgtc ctaaccacta
     3241 gacgaaggga gcgtaactgt gtcgctgccg aggcaggagc gctagtatat gcacctcgat
     3301 gccattgggc aatcccgaaa cttcaaccgg aagcgccaac atcatttcct ctgctacatc
     3361 accgttcagc ctgcgcgtca tcccgcgcga ccagcacacg atctcccgca aggacatcag
     3421 cccgaacgcc ctgcgcgtgc tttatcgcct gcgcgatgcc ggcttcggcg cctaccttgt
     3481 cggcggcgcg gtgcgcgatc tgctggtcaa tggccaaccc aaggatttcg acgtggccac
     3541 cgatgccacg cccgaacagg tcaagcagct gttccgcaac tgccgcctga tcggtcgtcg
     3601 gttccgcctc gcccacgtcg tgttcggccg cgagatcatc gaagtcgcca ccttccgtgc
     3661 caacagcgat gacggcagcg gcgaccgcga gatggaaaac ggcatgctcg tgcgcgacaa
     3721 cgtgtacggc accatcgaag acgacgccat ccgccgcgac ttcacctgca acgccctgta
     3781 ctacgccatc gaggacttct cggtgcgtga ttacaccggc ggcttcgaag acgtccaggc
     3841 gcgcctgatg aaactgatcg gcgaccccga gcagcgttat cgcgaagacc cggtgcgcat
     3901 gctgcgtgcg gtgcgcctgg cggccaagct cggcttccag atcgaagagg gcaccgccgc
     3961 gccgatcccg cacctggctg gcctgctcaa cgaagccgca ccggcacgcc tgttcgagga
     4021 ggtgctcaag ctgttcctgt ccgggcacgg cgtggccagc ttcgaaggcc ttgagcgtta
     4081 cggcctgctc gacgtgctgt tcccggaaag cgccaaagca ttgaagtcca accgcaccgg
     4141 tgcgctgcgc cgcatgctgg tcgagggcct ggccaacacc gatgcgcgcg tggccaacga
     4201 cgagccggtc tcgccggcgt tcctgttcgc gctgctgctg tggccggcgt tctgccgcgc
     4261 gcaggcgacc ctgctcaagc agggcgtggc accggaggag gcacagcgcc gtgctgccga
     4321 ccgtgtgacc gtgcagcagc tgagcaccat cgcattgccg cgccgctttt cgctgccgat
     4381 gcaggaaatc tggctgctgc agtcgcgctt cagttcgcgc cagcgcaagc gcgtgttccg
     4441 taccctgacc cacccgcgct tccgcgccgc gttcgatttc ctcagcctgc gccaggtcgc
     4501 ttcgtccgag catgcagtgg atgtcgagtt ctggcgcgaa gcacaggcgc agtccggtcg
     4561 cgagctggag tcgtcgctgg atgcgatgca cagtgaagac ggcgatgacg agagcggggc
     4621 accgcgcaag cgccgccgtc ggcgtcgacg tcccggtgct gctgcggcgg gcgagtaagc
     4681 gatgaccttg gcctggatcg gcctcggcgc caaccttggc gacgcggccg cgaccgtggg
     4741 cgcggcgatt gccgcgctgg acggcctgcc aggaacgcgc ctgcgacagg cctcgaggct
     4801 gtacgccacg ccggcgtggg gcaatgaaga ccagccgccg ttcgtcaacg cggtggcctc
     4861 ggtcgaaacc acattgccgg ccgatgagct gctgcaggcg atgctggcgc tggagcgggg
     4921 ctttggccgc gtgcgcgatc cggcggtgca ctgggggccg cgcgcactgg acctggacct
     4981 gctgctgtat ggcgcgcagg tgctcgacca tcccggcctg caggtaccgc atccctacat
     5041 gcacgagcgt gccttcgtgc tggtgccgct ggccgaaatc gcgccggatc tggccattcc
     5101 cggccatggc cgcgtgcagg atgcagtgat gcgggtggat gcctgcggga tcgcgccgat
     5161 agggtgataa tgcccgggtt atctcccccg gttatcagca catgagcacc cacgcagaca
     5221 gcaagccctg gaccgttccc gccctggccg aggccaagcg caatggccag aagctggtca
     5281 tgttgaccgc ctacgacgcc ggctttgccc gtaccttcga tgccaatggc gtcgacctga
     5341 tcctgatcgg cgattcgctg ggcatggtcg tgcagggcca tgattcgacc ctgccggtga
     5401 ccgtggccga catggtctac cacacccgcg ccgtagcccg tgtgctgcag cgtgcgctgc
     5461 tggtggccga cctgccgttc ggtgccgatg ccaccccgga gcgcgcgctg gatgcttcgc
     5521 tgcagctgct gcaggccggt gccgagatgg tcaagatcga aggtgccggc ttcaaggtcg
     5581 acatcatccg ctacctggtc gagcgtgaga ttccggtctg ctcgcacctg ggcctgaccc
     5641 cgcagtcggt gctgcgcctg ggcggcttca agatccaggg ccgtggcgat gccgcgcgcc
     5701 agctggtgga agatgccagg gccgtggccg ctgccggcgc cagcatcatg gtgctcgaat
     5761 gcgtgccgac cccggtcgcc gccgaagtga ccgcggcggt ggatgttccg accatcggca
     5821 tcggtgccgg cccgcagtgc gacggccagg tgctggtgct gcacgatttc ctcggcctgg
     5881 acagtggcca tcgccgtccc aagttcgtca aggatttcct tgccgaaggc ggttcggtgg
     5941 ccggtgccac ccgcgcctat gccgacgccg tgcgcgacgg cagcttcccc gacgaacagc
     6001 acgcctacgc ccaatgatcc agaccttcaa cgagctcggc gcgctgcgcg agcagatcgc
     6061 ccagtggaag cgcgagggcc tgcgcgtggc gctggtgccg accatgggca acctgcatgg
     6121 tggccaccat tcgctggtga ccctggcccg ccagtacgcc gacaaggtgg tgacgagtat
     6181 cttcgtcaac ccgacccagt tcgggccgaa cgaggacttc agccgctacc cgcgcacgcc
     6241 cgaggctgac gtggccgggc tggagcaggc cggctgcgat gcggtgtggc tgcccagcgt
     6301 cgaggcgatg tatccgctgg gcgtggacaa gaccacgcag atgcacgcgc cgggtgtcag
     6361 tgaagtgctg gaaggcgcca gccgcccggg ccacttcgac ggcgtgtgca cggtggtggc
     6421 gcgcctgttc ctgcaggtgc agccggatgt ggccgtgttc ggccgcaagg attaccagca
     6481 gctggccgtg atcaggcaga tggtggccga gctgtcgttc ccggtccaga tcgtcggtgc
     6541 cgagatcgtg cgcgacgagg atggcctggc caagagttcg cgcaaccagt acctcaacgc
     6601 cgaacagcga ccggttgcga cgaccattca ccgcacgctg ctgggcatgc gcgaaggcta
     6661 cgtggccggg cacacgcggg tgcagatcga ggccgacgcc acggcggcgc tgcaggcggc
     6721 cggtttccag gtcgactacg ccgtgctgcg cacgcccgag ctggccgagc cgaccttcga
     6781 cggcggtggc cgcgtggcgc tgatcgccgc gcgcctgggc acgacgcgcc tgattgacaa
     6841 cctggagttc tgagccgcac gcggcttggg ggcgcccgca acgggcgcct ctgcacttcc
     6901 cacggacggg agaccggaaa tgaaagcccc cagcactgat accggccgcc tcgcccaggc
     6961 ctcgatcctg gcggtgctgg cggcaggcat gttgccggcc cagctgtttg gcggcctgtt
     7021 gttcgcgctc gaattcaggc gtacgccgat gcctgcgctc accggtggtg ggctgatgtt
     7081 cgtactggcc gtctgcaatg ccatcgcggt gttgctgccg atggcgctga tcctgcagtc
     7141 tcagcagcgc ctgcgccggg ccggcttcgt gctggtcggc ttcgggctgg gcgcgctggc
     7201 catggccacc tgcgcctggc cgggggaaaa ccaggggccc tggctgcagc gcctgcgcta
     7261 cgtcgatacc ttcgatgtga tcagctatgc cttgcaggtg ctggccgcgg gaggcttcgg
     7321 gctggtcgcc gggctggcct tccatacggt gttccggctg tctctggaag gcagttccgg
     7381 gcacgcagcg ccgccgccgc cgggggaggg cacctgaaca gccttcagcg tcctgctgca
     7441 gccccctgac gatggtcaag cgggtgctag aatccgctct ttcctttgcc gttgcagcgc
     7501 ccccatgcac ctgtccctgc tcaagaccaa gatccaccgc gccaccgtca cccattccga
     7561 gctgaactac gaaggctcga tcgccatcga tgacaacctg ctggctgcca ccggcatccg
     7621 cgagttcgaa caggtgcaca tctgggacgt gaccaacggt gcgcgcttct cgacctatgc
     7681 catccgcgcc gaagccggca gcggcgttgt ctcgctcaac ggtggcgccg cgcgccacgt
     7741 gcaggtcggc gacatcatca tcatcgccgc gttcgccagc atgaccgagc aggaagctga
     7801 cagcttcaag ccgaagctgg tgtacgttga tggcaagaac cagatcaccc acaccaacga
     7861 cacgatcccg acccaggccg catgacaacg aacaacggat tcgactcgct gcattcccat
     7921 gcccagcgcc tgaagggcgc aagcatcccc agcctgctcg ccgccgaacc cggccgcgtg
     7981 caggatctgg cgctgcgggt cggtccgttg tacgtcaact tcgcccggca gaaatacgat
     8041 gccgcggcgc tgcaggcatt gctggctttg gccgccgagc gtgatgtcgg cggtgccatc
     8101 acccgcctgt tccgtggcga gcaggtcaat ctgaccgaag gtcgcgccgc gctgcacacc
     8161 gcgctgcgtg gcgatgtggt cgatgcgccg gttgccgccg aggcctatgc caccgcgcgc
     8221 acgatccgcc agcgcatggg cgtgctggtg cgcgcgctgg aagacagcgg cgtcaccgac
     8281 gtggtcagcg tcggcatcgg cggttccgat ctcggtccgc gcctggtcgc cgatgcgctg
     8341 cgcccggtca gcggcgcgcg cctgcgcgtg catttcgtgt cgaacgtgga cggcgccgcc
     8401 atgcagcgca cgctggccac gctggatccg gccaggaccg ccggcatcct catttccaag
     8461 accttcggta cccaggaaac cctgctcaac gggcagatcc tgcacgactg gctggggggc
     8521 agcgagcgcc tgtacgcggt cagcgccaac cccgagcgtg cggccaaggc cttcgccatc
     8581 gccgccgatc gcgtgctgcc gatgtgggat tgggtcggtg gccgttattc gctgtggtcg
     8641 gccgtcggtt tcccgattgc actggccatc ggtttcgagc gtttcgaaca actgctggaa
     8701 ggtgccgcgc agatggacgc gcatgcactg gatgcgccgc tggagcgcaa cctgccggtg
     8761 ctgcacggcc tgaccgacat ctggaaccgc aacgtgctgg gccatgccac gcacgcggtg
     8821 atgacctacg accagcgcct ggcgttgctg ccggcctacc tgcagcagct ggtgatggaa
     8881 agcctgggca agcgcgtgca gcgtgatggg cagccggtca ccaccgacac cgtgccggtg
     8941 tggtggggcg gggcgggcac cgacgtgcag cacagtttct tccaggcgct gcaccagggc
     9001 accagcatcg tgccggccga tttcatcggc tgcgtgcaca acgatgatcc ctacacgatc
     9061 aatcatcagg cgctgctggc caacctgctg gcacagaccg aggcgctggc caacggccag
     9121 agcagcgacg acccgcaccg cgattatccg ggcggccgcc cgagcacgct gatcctgctc
     9181 gacgcgctga ccccgcaggc gctgggtgcg ctgatcgcca tgtacgagca cgccgtgtac
     9241 gtgcagtcgg tgatctggaa catcaacgcc ttcgaccagt tcggcgttga actgggcaag
     9301 cagctggcca gtggcctgct gccggcgctg cagggcgagg atgtggcggt tgccgatccg
     9361 atgacccgcg agattcttgc gcggctgaag ggctgatacg gggtgcggat gggccggcgc
     9421 cagccggcca tcccatgtct ctccggttgc cttcgatccg gtcgcgcatg aaggctgcgc
     9481 ggccactcat tccgtcctgt ttccgtgctg cacatgccgc gcttccgcgt gcctgccgca
     9541 gcgcagcttg actgtgcatt gcgtgccaat gcagtgtgca cgggcggctg tacctgtcat
     9601 ccagtatcgc tcgcagcatg atgttgatgc cagggactgg ccgtatccga aggaacgtgg
     9661 aatcgatcca cgttctcaac gcctcatgtt gtgaatgaca ggagattgcg aatggatctg
     9721 aatgacgatg ttgtgtccgg ctggctcaac ggcgcggacg atgtggatgg gtgcgccaac
     9781 cctgcgggtt cgctgttcat ctacggtgcg gcagccaccg aagcggccct caccggagct
     9841 tcggacacca tgatcaccgg gggcaccaac gagtgcacca ccacggtatc ggtgatcaac
     9901 cactgcctgt gttgctgatg taacccgagc cggcacgcag aggcatgcag ctgcgtgccg
     9961 gcgactggaa cagacttccc gataccttgc agggggcgta atgaccgctt ctccggctgc
    10021 ggctgcgttt gcgcgcatca ccgaacattt ccttgcccat gcgcgcgccg cgttggcgac
    10081 tggcctgcat gaccctgcca ttgcgctgca gcccggtgag cgcgaactgc tgcacgcgca
    10141 gggcgacgcg gcgctgcgtg agcatgccca gctcaagctc aaccgcgtgc tgctgctgga
    10201 actgcacgcc gctgcacgca gtggtgacat cggcccgctg ggcagtgcgg gtgcgctgga
    10261 cgaattcgtt gccctggcca cgagcgaggg cttccgtacg catctgcagc gacgctatcc
    10321 ggtgctgctg ccgcgcctga cgcgcatgct cgaaggacaa tgtgcggcgg tggtggagct
    10381 cgctgtgcgc atcggaagtg atcgtgcggc gctggcaggg ttgctgggcg cgccggcggg
    10441 cacgctgcat gccgttgcat tgggacgggg tgacctgcat ggtggcggcc ggactgtggc
    10501 acggctgcag ttcgaaggcg gcacggtgat gtacaagcca cgctcattgc gcatcgatgc
    10561 gacgctcgac ggcctgttgt gcactctctt cggtgacggc cctgaccgcg tatgcgtgcc
    10621 gaaggtgatt gatcgtggca gccacggctg ggccgccttc gccgcgcacc gctactgtgc
    10681 cgatgacgtt gaactgcgtg cctactatcg cggtcttggc cattggctgg cgatcctgcg
    10741 cctggtgggt ggcaccgaca tccatctgga gaacctgatc gcggtcgggc cggtgccggt
    10801 tgtgatcgac gccgaaagcg tgttctcccg ggtaatcgaa atcgagccgt caggacttgg
    10861 cgatgcgtac gacaccgccg tcaagctgat gcgcaattca gtgctgcgta ccggaatcgt
    10921 gccgttccgt actgccggcc tgggcatgga aggcgtggat ctgtctgcag ccggcgcact
    10981 gccgggcgag cagccgcggg tgcaggtgcc ggtgattgtc gagggcggga cggaaccggc
    11041 ccggttgggc atggtcgagg ccgaggtctc cgttgcgcag aatcatccca gcgcgcagcc
    11101 cgatgtgtcg ttgtactggg accacatcag cgagggcttc atcgacgcca gtgggcgcct
    11161 gcgcgcgctc gatgccaagg gcgaactgat gccactcctg gcggctttcg aaggctgtca
    11221 ggtgcgcgac gtgcggcggc cgacaatggc ctacgcagag ctcgggcgga tgctctggca
    11281 tccagcctcg ctgcacaacg aagcccaggc ggttgaacgc gcgatcgatc tgctggtgcg
    11341 caatgcagcg gtgtcaccgg ctgcgccatc ggacctggac accgtccgta gcgaagtgga
    11401 tgacctgcgc cacggtgaca ttccgatctt cacttcgcag ctggacgcag cgcgcatccg
    11461 ctccatcgcc gacaactggc gtgcgatgcg catcgacctg gaagacgtga ccatccgcag
    11521 cacgctggtg gccaccgacc tgaaccagca tgcgctggcc cgcgccgagg ctcgatccgg
    11581 ctacagctat gccgcacagc atccgcgtgc ggacgacctg gacgcgcgcc gtcgtacgct
    11641 ggccgcgcgc gcggtggaga gcctgctgcg gctggcggtg catggtgagg acggttcgat
    11701 gacctggatc acccccgagg tgacccgtac cggatggacc gtccagccgg tgcagcccga
    11761 cctgtatttc gggctgggag gtattgcatt cgcattggcg gcttaccacc gggaagtgga
    11821 gcaggggcgt gccgacccgg tagcggggct gggcccggcc atcgatggcg cccttgcggt
    11881 gttccagacc atgtgtgagc agcaccccgc cgagatcgat ggtggattcg tcggaaccgg
    11941 ttcacagata tggacattgc tggcattgca cgacctcttg cagcgaccgg cgttgctggt
    12001 gctggcggaa cgttgtgcgg aagccgcaga gcgtcgcggc ttccaggagg cgacaaagtt
    12061 cgaactgatt gatggcgtgt ccggcatgat cctgccgttg ctgtcgctgg ccgcggctac
    12121 cgggaacgca cgctggctgg agctggccgc cgcagcgggg cgtcgcatgc aggaagcggc
    12181 gatcgtcgat gccgacggcg cacgctggcc gacgccacag ttccgagagc cgatcggtgg
    12241 cttcggccac ggtgcgatgg gcatgggctg ggcgctggca cggctggcgc gttcggatgc
    12301 cggcagcgtg cctgagcgag cggcctggcg gcagttggcc gaaggagcgt ttgcgttcca
    12361 ggcggcgctg ttcgaaccgc ataccgggca ctggcgtgac atccacctgc aggatgggca
    12421 gaagaacttc ccgacctggt gccatggcag cgttggaatc ggtctggcgg cggcggatct
    12481 gtatgcccgc accggcgatc ccgcgcagtt gcgtgacatg cggcgggctg tggccgacgc
    12541 gcgcggcaaa tgggggttca gccacaccct gtgccacggc gatgtgtcca cccgggagct
    12601 gctggtgctg gcggctgcgc tggatccgga gggatgtccc tatccgcagg atgaggcggc
    12661 catcgagatc gtttcttcaa tcgaggagca ccagggcatg gtcggcggac tgacccgcgc
    12721 ggccttcact ccgggcctga tgatcggcct ggcaggtgcg atctatggtt tcctgcgcat
    12781 gcatccggcc tgcgcgctgc cgtcgccgtt gctgcaggag acgacagtgg cccgggtcga
    12841 tgcaccggca tcgcgttcca ttaccgcgca ggaccgagcg gtgctggccg aggtctgagc
    12901 cggacggggc cggccgcgat caacggctgg gatcgcgttc cgggctcggt cgcttggcca
    12961 gcttgcgctg cagcgaacgc cggtgcatgc cgagcaggcg tgcggccgcc gatacgttgc
    13021 caccggtctc gtgcatcgcc tgctggatgt gttcccactg caggcggctg atcggcgtca
    13081 tcgcgtccgg cacttccatt tcgccatcgt cggccgggcc gtcatcttcc tcgccgaggg
    13141 cgcgcaggat catcggtacc gtggccggct tcggcaggta gtcgtcggcc ccgagcttga
    13201 ttgcttccac cgcggtggcg atgctggcgt agccggtcac cagcaggatg cgcatgtccg
    13261 cgcgcagcgc gcgcagtggt tggatcagtg ccaggccgga atcgctgccc agcttcaggt
    13321 cgatcagcgc gaacgccggc ggatgctggc gggccagtgc cagtgcactg gcggcgtcct
    13381 gcgcggtctg ggtttccagc cccttgcggg ccaggctgcg ctgcagggta cgcaggtaca
    13441 gctcgtcgtc gtcgaccagc aggccgaggg ttgaggtgct catggggttt cctcgcgtag
    13501 ggccagcggc aggcggaagc cgacgcggct gccggccccc tgggccgggc gcatccacat
    13561 ctcgccgtcg aggcgttcga tggtggcatg ggacagggcc aggccgacgc ccatgccctc
    13621 gcttttgctg ctgccgaaca gcttgcccgg cagcaccgcg gcgcgggcgt cgaagccgtg
    13681 gccgtagtcg cggacttcgc cgatcaggtc gtcgccttcg atgcgcaggt ccaggtccac
    13741 gcgcggccgg ccggcctgtt cgccggcatc agcggcattg ttgagcagga ccatcagcag
    13801 atggcccacg cccgggtcga gtggcagccg cagcggcgca tcgtcgttgc ggtgcaggtc
    13861 gatggtcggc cgcaccaggc gccactgttc cagtacctgc tgcgcgctgg agtggctgcg
    13921 ccccggtgca tcggccgagg ccggtgcggc cagcgccagc acacgctcgc ggcactgcac
    13981 cagcagctcg cgcagggttt ccatgtcctc gcgcacttcc ggctcttcac tgcgctcggc
    14041 cacgtcgtcg gcgagcaggg tcatggtggc cagcggtgta ttcagttcgt gcgccaccga
    14101 cgcggcatgg gtggccaggg cgacgatgcc ctcgttgcgg gcgaagcgtt cgcgcagcgc
    14161 cgacagttcc agttcgcgct ggcgcagcgc cagtgccagg cgggtggaga aggccagcac
    14221 cactgcggcg gaaatcagga aattggcgac cacgccccag cggttgaggt cctgcgcgcg
    14281 gaaatagccg tccggcagcg gctggccgaa gatgccgctg gcggcgtagc cgagcaggca
    14341 ggccagggcc actgccagtg cccagcgcag gggcagggcg aaggcggcca gcgcgatcag
    14401 gatcaggaac agtgaactga acgggttggc catgccgccg ctccagccca ccatccaggt
    14461 caggatgatc acgtccacca ggatatggcc gaatgcggtc agcggggcgg tgtcggccgc
    14521 ttccgggcgc agctgggtgt agatgttgaa caaggtgagc acggccacgc cggcccatag
    14581 tggcagctgg ggcaacggca ggcccagcac ccagctggcg accaggatgg tggcggcctg
    14641 gccacctacg gcaagccagc gcaggctgca cagggttcgg agaaacgggg cgtcgggacc
    14701 ggtcattcac gctcatcgta tgcgttcacg cgtgaccgtg cctgcgacaa tcggccgcag
    14761 ccgtgccgcc ggctgaatgc gagtcacccg gaatgcggga gcgggcggta gaatgcgccc
    14821 atgcacgacg ccgtcacccg cccgactccc ccctccgatg ccacctcctg gccccgccgc
    14881 cagacccacg ccgtgcagat cggcggggtc accgtaggtg gaggcaagcc ggtggtggtg
    14941 cagtcgatga ccaacaccga cacgtccgac gtggcctcca gcgtgaagca ggtggccgag
    15001 ctgtggcgtg cgggttcgga aatggtgcgt ttgaccgtca acaccgttga agccgctgcg
    15061 gcgatcccgc gcatcgtcga caagctggcg atgatgggca tcgacgtgcc gctgatcggt
    15121 gacttccact acaacggcca ccagctgctg accgccgagc cggcgtgtgc cgaagcgctg
    15181 gccaagtacc gcatcaaccc gggcaacgtc ggcttcggca agaagaagga cctgcagttc
    15241 gcccagttga tcgagttcgc gatccgctac aacaagccgg tgcgcatcgg cgccaactgg
    15301 ggctcgctgg accaggccct ggcggcgaag ctgatggacg agaacaacct gcgcgaacag
    15361 ccctgggacg ccggtcgcgt gctgcgcgag gcgctgatcc gctcggcgct ggattcggcc
    15421 gagcaggcag tggaactcgg cctgccgcgc gaccgcatcg tgctgtcggc caaggtcagc
    15481 ggcgtgcagg agctgatcgc ggtataccgc gacctggccc agcgctcgga tttcgccctg
    15541 cacctgggcc tgaccgaagc cggtatcggc agcaagggca tcgtcgcgtc gtcggcggcg
    15601 ctgggcgtgc tgctgcagga aggcatcggt gacaccatcc gcatctcgct gaccccggaa
    15661 ccgggccagt cgcgcacgca ggaagtgatc gtcgcccagg aactgctgca gaccaccggc
    15721 caacgcgcct tcacgccgct ggtcacggcc tgcccgggct gcggccgcac cacctcggag
    15781 ttcttccagg agctggccaa ggtggtgcag aaccacgtgc gcgagaagat gccgctgtgg
    15841 aagatccacc acccgggggc ggagaacatg accctggcgg tgatgggctg catcgtgaac
    15901 gggccgggcg agtcgcgcca tgccaacatc ggcatctcgc tgccgggcac gggcgaaaca
    15961 cccgcagcgc cggtgtttgt cgatggcgag aagaaggtga ccctgcgcgg cgacaacatc
    16021 gcccaggagt tcgtcgccct gatcgacgat tacgtcgaac acacgtatgt ccgaagcgcc
    16081 ggataagcct gcaatcctcg ctgcaccgga gtccgcctcc ggtttccgcc actggatggc
    16141 gcgcaatgcc tggcgcctgg tcctgctgtt cggcggcgtg ctgctgccgc tggctggctt
    16201 cgtcgccctg gcggacgagg tgcacgagtt tgaatcgttc catttcgacg cgccgctgct
    16261 gtggcagatg catggcctgc actcgccact gctggaccgc ttcttcgtgc tcatttccaa
    16321 actgggctat gagtggttcc tgatcccggc cgacgtgctg atcatcggcg tgctgctggg
    16381 ctaccggcgc tggcgcgagg ccaccttcgt ggcggtcagc ttcgtcggct cggcgctgct
    16441 gaacatgggc agcaagcact tcttccagcg ccagcgcccc agcctgtggg aatcgatcgc
    16501 gccggaatcg acgttcagct ttcccagcgg ccacgcgatg ggctcgatga ccctggcggt
    16561 gaccctggta ctgctggcct ggaacactcg ctggcgctgg ccggtgctgc tgctggcacc
    16621 ggcattcagc ctgctggtca gcgtctcccg ggtctatctg ggggtgcatt acccctccga
    16681 tatcctggcc ggatggtgtg ccgcgctggt ttgggtggta gggtgctatc tggtcatgtt
    16741 cagtcgccgg cacccttggc ggcatcatgg cacgcggcca gcgaaggcca gcgaagcatc
    16801 atcacagggg gattgacgtg gatgccccgc gcgggacgtc tacgtgatag atcagttgtt
    16861 tcgttgcagc aggttctgca agacaggggg caagcacaac gcgcggtact gtgatgcgca
    16921 aggcagattg ccggggccgc attccgaacg cgcttgcagg gtatcggcac cctgcctagc
    16981 ttgacctgca atggccgcat tcgaagaggt acgtgaatga cgattcgagt ctacctggtg
    17041 gatgaccacg cgctggtccg caccgggatg aagatgattc tgtcggggga agccgacatc
    17101 gaggtggtgg gcgaagccga gaccggcgaa gacgcgctgc gtgaagtccg ccagctgctg
    17161 ccggatgtgg tgctgtgtga cctgcacctg ccgggtgtga gcggcatgga agtgaccgag
    17221 cgcatcgtgc gcagccaccg caacacccgc gtagtgatcg tgtcggtgct ggaagatggc
    17281 ccgctgccga agcggctgct cgaagccggc gcggccggat atatcggcaa gggttgtgat
    17341 gcgcaggaac tgctgcgcgc ggtgcgtgac gtggcaggtg ggcgccgcta cctgggcacc
    17401 agcatcgcgc agaatctggc actgtcgacg gtggaaggca acggttcgcc gttcgacagc
    17461 ctgtcgccgc gcgagctgga agtggcgttg ctgctgaccc agggcctgcg ccaggaagac
    17521 atcgcccgcc gtctgagcct gagcgcgaag acggtgaaca cgcataaggc gcggttgttc
    17581 gagaagatgg ggatccacga caacatcgcg ttggcgcgga tggccagcca atacgggctg
    17641 gtggatccgg cacggccgct gtaagggatt cggccaacgg ctgagcccct cgcggtggtg
    17701 gttcggttgg attctggggg atggccgggc ggatgggttg agcaggggac gctgcaagta
    17761 cgtccctgta agctcggtcg ccgcatccat gcggctcacg cccctgcaca acccatccgc
    17821 ccggccacgg acagtttccg tgcgcgtcca ccgcggaatg aagaaggaag agcgggagcg
    17881 ggtcgcgcgc tttgcgcgct cgtagcttgg agtcggatcc ctttcccgac gggaaagggc
    17941 tctgaccccg atcctcttgt cagtggccgc gcacgcgctt gatgatcttg gcggcgtcgg
    18001 tggcgctggc gcgcaccttg tcccattcgc cattggcgat ccagttgccc ggcaccatcc
    18061 acgaaccgcc gatgcagacc acgttcttct gctcgaggta ctcggcggcg gtgttttcgg
    18121 tgatgccgcc ggtcgggcac agcttcaggt cggcgaccgg gccggccagg cccttgatca
    18181 tcgccaggcc acccacggcc gtggccggga acagcttgca cacgcggaag ccgcgcgcat
    18241 agagcgacag aagctcggtc ggcgtggccg cacccggcac caccggtagc ggcgcagcgg
    18301 ccaatgcatc ggccagcgcc ggcggcgtac caggcgtcac caggaagtcc gcgcccgcat
    18361 cgatcgactg ctgcatctgc tccacggtca gcaccgtgcc cgcgcccacc accacatccg
    18421 gcagctcgcg cttgagcatc gccagcgctt ccatcgccac cggtgtccgc agcgtcagct
    18481 cgatggccgg caggccacct tccagcagcg ccgcactgac cgcccgcgcc tggtccagcg
    18541 tatgaatcgt caccaccggc aggatgcccg ccgcatgcaa cagctccgcc gccttcacct
    18601 gatgttgttc gatacccatg cttttgccct tgcctttgct cttcttgatt cagtggccgc
    18661 agcgcagatg acgcgccggg aattgtccaa gggcagtaga gcgccctggc cgggaccgtg
    18721 agcggcatgg atgccgcgat cgagccccaa tggatgggtt tacggcgtgt cccggccagg
    18781 gcgctctgcc caggccggga agcctgccgc ggcttttcgc ttcaggcgtc cttcgcctca
    18841 tgcggtgccg ccgccgccgc ggcatcatgc cccagctcgt actccgcgtc gtaatcccac
    18901 ggcccaccat cggccgccgc cggcccacac gaaatcgaaa tcgccccctg gtccgccgga
    18961 cccaccacgc gacggttgat cgcaaacaga ttgcggccca ggtcatgcgc ggccggcgcg
    19021 gtgttcggcg ccagcggacg tgctgcccat tccgccgcat ccaccagcac ttccagcgtg
    19081 ccggcctcgc catccaggcg gatcatgtcg ccttcgcgca ctttggccag cgggccaccg
    19141 cgcgccgctt ccggcgtcac gtggatcgcc gccggaatct tgcccgaggc gccggacagg
    19201 cggccgtcgg tgaccagtgc cacacgccgg ccctggttct gcagcaggcc cagcagcggc
    19261 gccagcgaat gcagttcggg catgccgttc gcacgcgggc cctggtatcg caccaccgcc
    19321 acaaaatcct gcggcagcag gccaccggcg tgcagcttgt tcaaaacctg tggtgcatcc
    19381 accaccaccg ccggtgcttc gatcgtgcgg tactgcggct tcaccgccga cagcttgatc
    19441 agcgacttgc ccaggttgcc gcgcagcagg cgcaggccgc cctggtgttc gaacgggttg
    19501 tcgacaccgc gcactacttc gtcatcggcg ctgcgttcca ggcccggcag atagaccagc
    19561 tggctgtcgc gcagctgcgg ctcgcgcgca tagtcggcca tgccgccacg cgcgacgctc
    19621 acgaggtcgc cgtgcatcag gcccgccttg atcagctcgc cgaacacgaa cgccgggccg
    19681 ccggccgcag cgaagcggtt cacgtcggcg tcgccgttcg gatagacgcg ggccagcagc
    19741 gggatcagct gcgatagctc gtcgaagtcg tcccaggtca gcacgatgcc ggcggcgcgt
    19801 gccacggcga tccaatggat ggtgtgattg gtcgacccac cggttgccat cagcgcgatg
    19861 accgcgttga tgatcgcgcg ctcgtcgatg atccggccca gcggacggaa gtcatcgccc
    19921 agcgcggtga tgtgcagcgc acgttcggtg gcttcgcggg tcagtgcatc acgcagcggc
    19981 gtgcccgggt tgacgaacga cgcacccggc agctgcacgc ccatcgcttc cagcagcacc
    20041 tggttggaat tggcggtgcc gtagaaggtg caggtgccag cgccgtggta cgacgcggac
    20101 tcggcttcca gaagctcttc gcgggtggct tcgccggcgg cgtagcgttc gcgcacttcg
    20161 gccttctgct tgttcggaat gcccggggtc atcgggccgg ccggcacgaa caccgccggc
    20221 aggtgaccga aggccagtgc accgatcagc aggcccggca cgatcttgtc gcacacaccg
    20281 aggtagacgg tggtgtcgaa catgtcgtgg ctgagcccga tggcggtcgc ctgtgcgatc
    20341 acatcgcgcg agaacagcga cagttccatg ccgcctcggc cctgggtgac gccgtcgcac
    20401 atcgccggca cgccgccggc cacctgtgcg gtggcgccca gctcgcgggc gatctcgcgg
    20461 atctgctcgg gataggtctc gaacggctgg tgcgccgaca gcatgtcgtt gtaggcggtg
    20521 atgatgccca ggttcggcgt cacgccaccg cgcaggcggc tcttgtcggt gccgccacag
    20581 gcggcgaatc cgtgggcgag gttgccgcag ctcaggcggc tgcggaacgg gccctcacgc
    20641 agggaggcat cgatcgccgc cagataggcg gcacgcgagg cggcgctgcg gcggatgaca
    20701 cgctcagtga tggcttgcag ttgcggatgg aggctcattg gctaccggcg ttcgtggtgg
    20761 cgagaggcaa gcggcggcgc ggcgccgccg ccgacatcaa tcagcccagt gcacgcgcag
    20821 gcgcgcgccg tccaggttga ttgcattgag gatcgggtac tgctgggcgt cgttgctgtc
    20881 cagcgcctgg cgcagcacct gcagcttctg cttgccgcgc agcagcagca ggcgctggcg
    20941 gcactggccc agcccgtgcg gggtcagcgt gatgcgcagc ggccactggt tcgcgcccgg
    21001 gcagccggtg gcgtccagtg ccgcgtaggg cagggtgctt tccagtgcgc ggaccaggtc
    21061 cttcgagccc gggaacagcg aggcggtgtg gccgtcgttg cccatgccca gtgccaccag
    21121 gctcggcggc tggctgtgct gggcctgcag gttggcggtg taaacgcatt ccggcagcgg
    21181 ctttccgatc cgtaccagcg gatcgaaatg cgcaccttcg gcgcgcttga gcaggtgctc
    21241 gcgcaccagc caggcgttgc tgtcgcgatc ctgcggcgac agccagcgct cgtcggccag
    21301 gctcacttcc acccggtccc agtgcacgtc caactcggcc agcgcctggt agaccggcgc
    21361 cggcgtggtg ccgccggaca acaggatgcg ggcgcggccc acttcgttga tgtcgtggtt
    21421 gagggtctgc gccatctcgg cggccactgc ctcgatccag ccgtcggcat cgccgtggct
    21481 gatgaactcg atgcggtcgt cgtggaaggt gggactcatg cggcaactcc aggtgcgtca
    21541 cgttcggcgt cggctgcata ggcggcggcg cccagcaatc cggcgtgggg atgcatcacg
    21601 gccaacgagg gaacgcgcgc catgatcgaa gagaaccgcc ccttgtgttc gaagcgctgg
    21661 cggaaaccag agtgctgcag cgaatcgagc atcttcggag tcagaccgcc ggtcaggaac
    21721 acgccatccc aggcaccctg ggtcagtacc aggtcgccgg caatggcgcc gaacaccgcg
    21781 cagaacacgt ccacggtgcg cattgcctgc ggatcgccat gcagggcacg ggcggtcacg
    21841 tccaccggct gcagctggcc gggatcgata ccggccatct cgcacaccgc gcgatggatg
    21901 ttgaccaggc cggggccgca gatcagtcgc tcgttggaga cgcggccgaa ctgctcggac
    21961 aggatttcca ggatgcggat ctcctccgga gttcccggcg ggaagctgac atggccgcct
    22021 tcggtttcca gcggatagca gcgtccgtgg cgcaggatca ggccaccgac acccaggccg
    22081 gtacccgggc cgatcaccgc gtagttgcgc ggctggcccg gcttgcccgg cacccaggcg
    22141 gcaccaccga cctggaccac gtcatcgggc tgcagcagtg aaatcgccat cgcctgtgcg
    22201 gcgaaatcgt tgatcaggtg cagttcgtcg aacccgagca tcgccgcggt gcggctgcgc
    22261 gagatcaccc acggatggtt ggtgatgcgc gcttcgtcac catcaacgcg accggccact
    22321 gcgaacacgc cgcggctggc ggtggcgccg atctgttcca gatggtggcg cgcggcatca
    22381 cccagcgatg ggaactccgc caccgcgtac tcgcggatgc tgtccttctg cagcggtgcg
    22441 tcctgcgagg tgtcggccag ggcgaagcgg gcgttggtgc cgccgatgtc ggcgaccagc
    22501 accggctgcg agctggcact catgccgagg ctccgctgtc cggcgcgtcc acgccctgcg
    22561 gcaggaactc gcccgcattg ctcgggcccc attggccggc ggggtagggc tccagcggca
    22621 gcttggcgtc cttccaggca tcggccacgc tgtcgatcca cgcccaggcg gcgcgcactt
    22681 cgtcatcgcg cacgaacagc gtgtggttgc cgttgaacgc atccaggaac aggcgctcgt
    22741 acgcgatgcg gcggtgcagg ccggtcggca ccgacagctc cagctccagc gggtgcagtt
    22801 ccagcgcgcc ccattccggg ccggccaggc tgctcatcag gcccagttcg atgttttcct
    22861 gcggctgcag ctggaacacc aggcggtttg gtgcggcc
//
