LOCUS       NZ_CP046588            10846 bp    DNA     circular CON 12-MAY-2024
DEFINITION  Stenotrophomonas sp. SXG-1 chromosome, complete genome.
ACCESSION   NZ_CP046588
VERSION     NZ_CP046588.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas sp. SXG-1
  ORGANISM  Stenotrophomonas sp. SXG-1
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas.
REFERENCE   1  (bases 1 to 4534602)
  AUTHORS   Zhang,X., Shang,B., Li,X., Li,Z. and Tao,S.
  TITLE     Complete genome sequence data of multidrug-resistant
            Stenotrophomonas sp. strain SXG-1
  JOURNAL   J Glob Antimicrob Resist 22, 206-209 (2020)
   PUBMED   32311503
REFERENCE   2  (bases 1 to 4534602)
  AUTHORS   Shang,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-DEC-2019) Guizhou Fisheries Research Institute,
            Guizhou Academy of Agricultural Sciences, No. 2448 South Section
            Huaxi Avenue, Huaxi District, Guiyang, Guiyang 550025, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 500.0x
            Sequencing Technology             :: Illumina HiSeq; Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014083965.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 12:38:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,125
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 4,012
            CDSs (with protein)               :: 4,012
            Genes (RNA)                       :: 91
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 22
            CDSs (without protein)            :: 22
            Pseudo Genes (ambiguous residues) :: 0 of 22
            Pseudo Genes (frameshifted)       :: 8 of 22
            Pseudo Genes (incomplete)         :: 13 of 22
            Pseudo Genes (internal stop)      :: 5 of 22
            Pseudo Genes (multiple problems)  :: 3 of 22
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:22:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1169628
            Orig. end                         :: 1180474
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP046588.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10846
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10846
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10846
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5846](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5846)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            348..572
                     /locus_tag="GOC52_RS05350"
     CDS             348..572
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479411.1"
                     /locus_tag="GOC52_RS05350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_010483459.1"
                     /transl_table=11
                     /translation="MAIVITLDRMLQERGMTLSELAGRIDITLANLSILKTGKARAIRF
                     STLDAICRELQCTPGDLLGHDPTQAQDAD"
     gene            616..2157
                     /locus_tag="GOC52_RS05355"
     CDS             616..2157
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1273: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659354.1"
                     /locus_tag="GOC52_RS05355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TerC family protein"
                     /protein_id="WP_019337054.1"
                     /transl_table=11
                     /translation="MEWLADPSIWMGLATLVVLEIVLGIDNLVFIAILADKLPPHQRDR
                     ARVIGLALALLMRLVLLAALAWIMKLTEPLLTLFDHSFSGRDLILLGGGLFLLFKGTME
                     LHERLEGRQHEDNGKKVYASFAMVVAQIVVLDAVFSLDSVITAVGMVDNLGVMYAAVTI
                     AMALMLVASKPLTRFVNKHPTVVVLCLGFLLMIGFSLVAEGLGYKIPKGYLYAAIAFSI
                     LVEAFNQWVRFNRERNERRQPFRQRTADAVLRMLGARPTNGHDDESADEHVDAEERLQP
                     AEHEMIRSVLGLADRPVSSVMTVRADVQWIDLARGQDDVVARLVASPHTRLLVGDGDLD
                     SLRGVVQSRDLLADLLQGKPLQLEGNLREPQYVLSSASALQALELIRQHPVPLAVAVDE
                     YGSVEGLVTANDLLAAIAGDLVDTQDERYGVVVQGEGQWEADGALTLDDLQRLAGVSLP
                     RSADYMTISGLVLERLGRLPDIGDAVEIADVRITVLAMEKRRIARLRVQRLDGMA"
     gene            2279..3415
                     /locus_tag="GOC52_RS05360"
     CDS             2279..3415
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004147841.1"
                     /locus_tag="GOC52_RS05360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metallophosphoesterase"
                     /protein_id="WP_049480135.1"
                     /sec_met_domain="Metallophos_2 (E-value: 9.8e-09, bitscore:
                     33.4, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAVLSTIGLLMGLYVAWRLFWPLRMPTWLKVVLSLLLVGVAVQL
                     RIVAMFWGTMASPEIPKLAIATLATGSTAVLLLALLMLALDVSLLASRLLRRPRAVAAL
                     RTRSLRPVAGLLALLVSGYGISQGMAVPQPRQIDVAIKDLPAAFDGYRVLQLTDIHASR
                     LLTGDWVRRVVDQSNALTPDLIVITGDLIDGSVEARRDDARPLVDLRAPDGVVAITGNH
                     EYYAQYQAWMQAFRALHMQVLENSHMQVRRGDAALTIAGVTDPVAARYGLPLPDMDAAL
                     AGADPSAPVILLDHRPRNAREAAARGVKLQLSGHTHGGQIIGMDQLVKRANGGYVSGRY
                     EVDGMTLYVSNGAGLWAGFPARIGVPSEITLITLRRAP"
     gene            complement(3552..4190)
                     /locus_tag="GOC52_RS05365"
     CDS             complement(3552..4190)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408497.1"
                     /locus_tag="GOC52_RS05365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="WP_191850841.1"
                     /transl_table=11
                     /translation="MAVSNTSSLHGWRLFVAIAVVLIAFAVAAFTLQPDVVEGSRAAIR
                     VTARTSFLLFLVAFTASSFASLLPGPFTRFLLRERRIVGLSFAFSHLLHAVAITAFGIL
                     NPAFWPARSALANLPGTIGYVAILALAITSHRGIARRMGPTAWRRLHVTGMWIIAAVFT
                     YSYFKRVPGNFWYAVPSALLFTAVVVRAIAKRAQSLRRDAHARPPLRSS"
     gene            complement(4274..5008)
                     /locus_tag="GOC52_RS05370"
     CDS             complement(4274..5008)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010483449.1"
                     /locus_tag="GOC52_RS05370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_049455587.1"
                     /transl_table=11
                     /translation="MAEPLATLQQRWADHVRDPSMPAPEGIDARRMAVYRRLCIDSLDS
                     LLAGSLPRLQAQLGDACWRDTVEHYYARHACHTPLFPQIAGEFAAWLGVQADLALPGWV
                     AELAHYESTQQALHIEARHTGQQPLHAPQAGSVLALSPLVRVLGYQWPVHEDAGQNGAP
                     TTMPTLLLLRRLGDFSLQVQELSPLAYALLSAFGDDGARAEDALQVLADLHGVAADELR
                     TACIPLLGDLCAAGVLVVPNDC"
     gene            complement(5001..5846)
                     /locus_tag="GOC52_RS05375"
     CDS             complement(5001..5846)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646321.1"
                     /locus_tag="GOC52_RS05375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_191850843.1"
                     /sec_met_domain="DUF692 (E-value: 3.7e-117, bitscore:
                     388.2, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLPLPSASAGLGLRRGLIDELLAMPADAIDFLEVSPDNWIGVGG
                     AHGAALRQLSERHRLTCHGLSLSLGGPDPLDRTLLTQTRAFLDLHQVQLYSEHLSYCAA
                     GGHVYDLLPLPFTTEAVHHVAGRIRQVQNTLGRRIAVENISYYAVPGADMSEIEFITAV
                     LAEADCDLLLDVNNVFVNACNNGYDAFDFLARVPAHRVASLHVAGHFDEDDGFKIDTHG
                     APVKGVVWALLGEAYARVGVRPTLLERDFNFPPLAELLAEVEQIRHAQADVLPPEVAHG
                     "
     gene            complement(5899..6375)
                     /locus_tag="GOC52_RS05380"
     CDS             complement(5899..6375)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005412584.1"
                     /locus_tag="GOC52_RS05380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_010483445.1"
                     /transl_table=11
                     /translation="MSVSTKNTAASRLPRIGAIGIALAGGLLLAGQAAAIQPLAIGAVA
                     MSAAAEGKCGEGKCGANKAATGKPAAKAKVAEGQCGEGKCGDASFARTDRDHDGRVSRA
                     EFNAVAAKRAAEFDRIDTDHDGYISEQEAHDYLRSVYTANGKPMPKGLFSRVND"
     misc_feature    6389..6402
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.9"
                     /tool="antismash"
     gene            complement(6475..7119)
                     /locus_tag="GOC52_RS05385"
     CDS             complement(6475..7119)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479418.1"
                     /locus_tag="GOC52_RS05385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DoxX family protein"
                     /protein_id="WP_010483443.1"
                     /transl_table=11
                     /translation="MISSASSVYTPRLDAVGRWLSPLALRALLAWEFFESGREKLGGQN
                     WFADLEGRFPFPFSTLPASLNWQLATWLELVGAVMLLLGLATRSVAYIFWVLTLVAIAA
                     VHWPDQWNSLGELWQGYAITDQGYGNFKLPLLFLAMLLPLILNGGGALSLDRLLAGPQR
                     AAAGNDGLGWGVSLIALLLPVAALLPGIGFGGALLGGALLLGYRLRRRRNA"
     misc_feature    complement(7295..7310)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.21"
                     /tool="antismash"
     gene            7414..8208
                     /locus_tag="GOC52_RS05390"
     CDS             7414..8208
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010483441.1"
                     /locus_tag="GOC52_RS05390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_191850845.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.8e-16, bitscore:
                     58.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTTLLAAALALAGVATPAFAAEADAGAAPTVILVHGAFADGSS
                     WNKVITTLHDWKLPAVAVQNPLTSLADDVAATRRAIAAAPGKVVLVGHSWGGTVITEAG
                     NDPKVQALVYVAAFAPDAGQSSAQQGEGYPVGPGLTRLQEKDGYLTLPADAIAQDFAPD
                     VMKKTAALLYSTQVPLKASALGESVTVAAWRSKPSWYVLSRDDRMLSPQLQAATAKRIG
                     AQLQLIGSSHVSLLSHPAQVADSILEAAGVKPAELPLAEQGG"
     gene            8212..8757
                     /locus_tag="GOC52_RS05395"
     CDS             8212..8757
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005415663.1"
                     /locus_tag="GOC52_RS05395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="redoxin family protein"
                     /protein_id="WP_019336971.1"
                     /transl_table=11
                     /translation="MGALRVYVLPLLLGLLGGAALLMALPSPEAGAHPAQAAPAAGFDG
                     GGPWHNSPPLALNQLRGQVVLVEFWTYACSNCLNVAPHVHQWHARYARQGLQVIGVHTP
                     EFAYEGLPGNVRKAIARLDITWPVVQDNQYRIWNAWGNRFWPALYLVDRQGRVVYRHYG
                     EGDYARTESEIQRLLASP"
     gene            8815..9555
                     /locus_tag="GOC52_RS05400"
     CDS             8815..9555
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659345.1"
                     /locus_tag="GOC52_RS05400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_010483437.1"
                     /transl_table=11
                     /translation="MNHVPHILVVDDDSEIRQMLADYLQRNGLRVSQADGGRAMRALMD
                     THAVDLVVLDVMMPGEDGLSLCRNLRAGKHRAVPVVLLTARDDETDRIIGLEMGADDYV
                     TKPFSSRELLARINAVIRRTQMLPPNLQVSEAGRQLAFGDWRLDTTARHLLDAQDTAYP
                     LSGAEFRLLRVFLDHANRVLSRDQLLSLTQGRDAELFDRSIDLLVSRVRQRLGDDAREP
                     TYIKTVRSEGYVFSVPVQLLGPEE"
ORIGIN
        1 ttcctgcact tctgcctcgg cctgggcgcg atcgtcgcgc tgctggtgct gtgcctgctg
       61 ttcctgcgcc atctgctgcg gctgctgaag tcggcggcgc gcgagcggcc gttcacccac
      121 gccaacgcgc agcgcctgca acgcatggcg tggttgatgc tggcgatgga gctgctgtcg
      181 atcctgatcg gcgcttacgc ggcctggatg gggcccgact tcacctggat ggaggtgggc
      241 ggcggcatgt cgatcaccgg cctggtggcg gtgctgatgc tgttcgtgct ggcgcgcgtg
      301 ttcgccgtgg gcgcagcgat gcgcgatgac ctcgatggtg tcatctgatg gcgattgtca
      361 tcaccctgga ccgcatgctg caggaacggg gcatgaccct gtccgagctg gctgggcgca
      421 tcgacatcac cctggccaac ctgtcgatcc tgaaaaccgg caaggcgcgt gccatccgct
      481 tttccaccct ggatgcgatc tgccgtgagc tgcagtgcac gcccggtgat ctgctcgggc
      541 atgacccgac gcaggcgcag gacgctgact gagtgctttc cctttttccc tacctactga
      601 cgaaacggac ctgaaatgga atggttggct gacccctcga tatggatggg ccttgcaacc
      661 ctggtcgtgc tggagatcgt tctcggcatc gacaacctgg tgttcatcgc gatccttgcc
      721 gacaagcttc cgccgcacca gcgtgaccgc gcgcgggtga tcggcctggc gctggccctg
      781 ctgatgcggc tggtgctgct ggccgcgctg gcctggatca tgaagctgac cgagccgctg
      841 ttgacgctgt tcgaccacag tttctccgga cgcgacctga tcctgctggg tggcggcctg
      901 ttcctgctgt tcaagggcac catggaactg catgagcggc tggaaggccg ccagcacgag
      961 gacaatggca agaaggtcta cgccagcttc gcgatggtcg tggcacagat cgtggtactc
     1021 gacgcggtgt tctcgctgga ctcggtgatc actgcggtcg gcatggtcga caacctgggc
     1081 gtgatgtacg ccgcggtgac catcgcgatg gcattgatgc tggtggccag caagccgctg
     1141 acccgcttcg tcaacaagca tcccacggtg gtggtgctgt gcctgggctt cctgctgatg
     1201 atcggtttca gcctggtggc cgagggcctg ggctacaaga tcccgaaggg ctacctgtac
     1261 gcagccatcg ccttctcgat cctggtcgag gcattcaacc agtgggtacg tttcaaccgc
     1321 gagcgcaacg agcgccgcca gccgttccgc caacgtactg cggatgcggt gctgcgcatg
     1381 ctgggcgcgc gcccgaccaa tggccacgac gacgaaagtg ctgacgaaca cgtcgatgcc
     1441 gaagagcgcc tgcagccggc cgagcacgag atgatccgca gcgtgctggg gctggcggat
     1501 cgcccggtgt cgagcgtgat gactgtgcgc gccgacgtgc agtggatcga cctggcgcgt
     1561 ggacaggacg acgtggtggc acgcctggtg gcatcgccgc acacccgcct gctggtcggc
     1621 gacggcgacc tggacagcct gcgaggcgtg gtgcagagcc gcgacctgct ggccgacctg
     1681 ctgcagggca agccgctgca gctggaaggc aacctgcgtg agccgcagta cgtgctgtcc
     1741 agcgccagtg cgctgcaggc gctggaactg atccgccagc acccggtgcc gctggcggtg
     1801 gcggtggacg agtacggcag cgtggaaggc ctggtgaccg ccaacgacct gttggcggcc
     1861 attgccggtg acctggtcga cacccaggac gagcgctatg gcgtggtcgt gcagggggaa
     1921 ggccagtggg aggccgacgg tgcgctgacc ctggacgatc tgcaacgcct ggcgggcgta
     1981 tcgctgccgc gcagtgccga ctacatgacc atctccggcc tggtgctgga gcgcctggga
     2041 cgcctgccgg acatcggtga cgcagtggag atcgcggatg tacgcatcac cgtactggcg
     2101 atggagaagc gtcgcattgc ccgcctgcgc gtgcagcgcc tcgacggaat ggcctgaccc
     2161 acctgttgct gtagagccga gcccatgctc ggctgcatgt tgagaagcca agcacgggct
     2221 cggctctaca caacacggcc ggcaaccgtc accatggcgg gcccgctttc tgtcatggat
     2281 ggttgcagtg ctgagtacga tcggtttgtt gatgggcctg tatgtggcct ggcgcctgtt
     2341 ctggccgctg cgcatgccca cctggctgaa ggtcgtgctg tcgctgctgc tggtgggcgt
     2401 tgccgtgcag ctgcgcatcg tcgccatgtt ctggggcacg atggcctcgc ccgagattcc
     2461 aaaactggcc atcgccaccc tggccaccgg ctccacggcg gtgttgctgt tggcgttgct
     2521 gatgctggcg ctggacgtga gcctgctcgc ttcccgcctg ctgcgccggc cacgcgcggt
     2581 agccgcattg cgcacgcgga gtctgcgacc ggtggccggc ttgctggccc tgctggtcag
     2641 tggttatggc atcagccagg gcatggcggt gccccagcct cggcagatcg acgtggcgat
     2701 caaggatctg ccggccgcgt tcgacggcta tcgcgtgctg cagctgaccg acatccacgc
     2761 cagccgcctg ctgaccggtg actgggtgcg cagggtggtg gaccagagca acgcactgac
     2821 gccggacctg atcgtgatca ccggcgacct gatcgacggc agtgtcgagg cccgccgtga
     2881 cgacgcgcgt ccactcgtgg acctgcgggc gccggacggc gtcgtcgcca tcaccggcaa
     2941 ccacgagtat tacgcgcagt accaggcgtg gatgcaggcg tttcgcgcgc tgcacatgca
     3001 ggtgctggag aacagccaca tgcaggtgcg gcgtggcgat gcggcgctga ccatcgccgg
     3061 tgtcaccgac ccggtggcgg cacgctacgg cctgccgctg ccggatatgg acgctgcatt
     3121 ggctggcgcc gatccctccg cgccggtgat cctgctcgat catcgcccac gcaatgcgcg
     3181 tgaggccgct gcgcgcggtg tgaagctgca gttgtccggg catacccacg gcggccagat
     3241 catcggcatg gaccagctgg tgaagcgggc caacggtggc tatgtctccg ggcgttacga
     3301 ggtggacggg atgacactgt acgtgagcaa tggcgctggc ctgtgggccg gattccccgc
     3361 gcgcatcggc gtgccgtcgg agatcaccct gatcaccctg cgccgcgccc cgtgacctga
     3421 agtggggtca gatccctttc cgcagggaat tcgctgcctt tcgtgctggg atccctctgt
     3481 agagccgagc ccaagctcgg ctgaaccaga ggcagccgag catgggctcg gctctacagg
     3541 taaccgcctc ctcaagaact ccgcagcggc ggccgcgcat gcgcatcgcg ccgcagcgac
     3601 tgcgcccgct tggcgatcgc acgcaccacg acggcggtga agagcaacgc ggagggcacc
     3661 gcgtaccaga agttgccggg cacgcgcttg aagtacgaat aggtgaacac tgcggcgatg
     3721 atccacatgc cggtcacgtg caggcgacgc cacgcagtgg gacccatgcg gcgggcgatg
     3781 ccacgatgcg aggtgatggc cagggcgagg atggctacat agccgatcgt gcccggcagg
     3841 ttggccaggg ctgagcgcgc cggccagaac gcggggttga ggatgccgaa ggcggtgatc
     3901 gccaccgcat gcagcaggtg cgagaacgcg aacgacaggc cgacgatgcg acgctcgcgc
     3961 agcaggaagc gggtgaacgg gccgggcagc aggctggcga acgaggatgc ggtgaaggcg
     4021 accaggaaca gcaggaacga tgtgcgtgcc gtcacccgga tcgccgcgcg gctgccctcg
     4081 accacgtcgg gctgcagggt gaacgccgcc actgcgaagg cgatcaggac cacggcgatg
     4141 gccacgaaca ggcgccagcc gtgcagggag gacgtattgg aaacagccat gatcaaacct
     4201 cgaatcagga aatgggtggc accggcctct ggccggccaa ggaatgggga gtgccggccg
     4261 ctggccggcg ccttcaacag tcgttcggca caaccagcac gccggccgcg cacaggtcgc
     4321 ccagcagcgg aatgcaggct gtgcgtagtt cgtcggcggc cacgccatgc agatcggcca
     4381 gtacctgcag cgcgtcttcc gcacgggcgc cgtcatcgcc gaacgccgac agcagcgcat
     4441 atgccagcgg tgaaagttcc tgcacctgca ggctgaagtc acccaggcgt cgcagcagca
     4501 gcaacgtcgg catcgtggta ggcgcaccgt tctggccggc gtcctcatgc acaggccact
     4561 ggtagcccag cacccgcacc agtggagaca gcgccagcac gctgcctgcc tgtggcgcat
     4621 gcaacggctg ctggccggtg tgccgcgctt caatgtgcag tgcctgctgc gtgctttcgt
     4681 aatgcgccag ttccgccacc cagcccggca gcgcgaggtc tgcctgcacg cccagccacg
     4741 cggcgaattc gccggcgatc tgcgggaaca acggggtatg gcaggcatgc cgcgcgtagt
     4801 agtgctccac ggtgtcgcgc cagcaggcat cacccagttg cgcctgcagg cgcggcaggc
     4861 tgcctgccag caggctgtcc aggctgtcga tgcagaggcg gcggtagacc gccatccgcc
     4921 gtgcatcgat gccctcaggc gcgggcatcg atgggtcgcg tacatggtcg gcccagcgct
     4981 gctgcaaggt ggccagcggc tcagccatgg gccacctcgg gcggcagcac atcggcctgc
     5041 gcgtggcgga tctgctccac ctcggccagc agctcggcca aaggcgggaa gttgaaatcg
     5101 cgctccagca gggtggggcg cacgccgaca cgcgcatagg cctcccccag cagcgcccag
     5161 accacgccct tcaccggcgc gccgtgggtg tcgatcttga agccatcgtc ttcgtcgaag
     5221 tggccggcca cgtgcagcga ggcgacgcga tgcgccggca cgcgtgccag gaaatcgaag
     5281 gcgtcgtagc cgttgttgca ggcgttgacg aagacattgt tgacgtccag cagcaggtcg
     5341 cagtcggcct cggccagcac tgcagtgatg aattcgatct cgctcatgtc cgcgcctggc
     5401 acggcgtagt aggagatgtt ctccacggcg atgcgccggc ccagtgtgtt ctgcacctgg
     5461 cggatgcgac cggcaacgtg atgcacggcc tcggtggtga acggcagcgg cagcaggtca
     5521 tagacatggc cgccggcggc gcagtagctc aggtgttcgc tgtacagctg cacctggtgc
     5581 aggtcgagga acgcgcgggt ctgcgtcagc agggtgcggt ccagcgggtc cggccctccc
     5641 agcgacagcg acaggccgtg gcaggtcagg cgatggcgct cactcagctg gcgcagcgcg
     5701 gcgccgtggg caccgccaac tccgatccag ttgtccggcg acacttcgag gaagtcgatg
     5761 gcatcggccg gcatcgccag cagttcatcg atcaggccac ggcgcaggcc gagaccggca
     5821 ctggcggaag gcaggggcaa gcgcatgcga cggtactcca gggcagtggc gccgccgtgg
     5881 cggcgccggg gggaacgatc agtcgttgac gcgggagaac aggcccttcg gcatcggttt
     5941 gccgttggcg gtgtagacac tgcgcaggta gtcgtgcgcc tcctgttcgc tgatgtagcc
     6001 gtcgtggtcg gtgtcgatgc ggtcgaattc agcggcgcgc ttggccgcca cggcgttgaa
     6061 ctcggcacgc gagacccggc cgtcgtggtc acggtcggtg cgggcaaacg aagcgtcgcc
     6121 gcacttgcct tcgccacact ggccttcggc caccttggcc ttggcggcag gcttgccagt
     6181 ggcggccttg ttggcgccgc acttgccttc accgcacttg ccttcggcgg cggcgctcat
     6241 ggccacggca ccgatggcca gtggctggat cgcggccgcc tggccggcca gcagcaggcc
     6301 accggccagg gcgatgccga tggcgccgat gcgcggcaga cgggaagcag cggtgttctt
     6361 ggtcgagacg gacatggtga tgactccttg gatgggcacg cagggcgtgc gggatggacg
     6421 ccgcttgaag gcgacggaaa cgaagggaag aagcgcggga agcggtgaag cggatcaggc
     6481 gttgcggcga cggcgcagtc ggtaacccag cagcagggcg ccgccgagta gtgcgccacc
     6541 gaaaccgata ccgggcagca gcgcggcgac cggcagcagc agggcgatca ggctcacgcc
     6601 ccagccgagg ccgtcgttgc ccgccgcggc gcgctgcggg ccggccagca ggcggtccag
     6661 gctgagtgca ccgccgccgt tgaggatcag cggcagcagc atggccagga acagcagcgg
     6721 cagcttgaag ttgccgtagc cctggtcggt gattgcgtag ccctgccaca gctcacccag
     6781 gctgttccat tggtccggcc agtgcacggc agcgatggca acaagggtca gcacccagaa
     6841 gatgtaggcc accgagcgcg tggccaggcc cagcagcagc atcaccgcgc ccaccagttc
     6901 cagccaggtg gccagctgcc agttgagtga cgcaggcagg gtggagaacg ggaaggggaa
     6961 acgcccttcc aggtcggcga accagttctg tccgcccagc ttctcgcggc ccgattcaaa
     7021 gaactcccag gccagcaggg cgcgcagcgc caatggcgag agccagcggc cgacggcgtc
     7081 caggcggggt gtatacacgg aagaagcgga gctgatcatg ggagtgtcct gcgggccagt
     7141 ggtcgatgga ggccattccg agccacgcag gtatcggcaa cgtgtgctgt tgcccggggt
     7201 tttgtcagcg actgtggctg tgtcaggggg ttcgtacagt cagatacaaa gacgccgcgt
     7261 cgggcgttcg ccgggccatg cccagcggcc gaatgtatcc aactgtagaa atccgccgcc
     7321 gccctacagt ccggtacaac tctgcctcgc agcgaaacag cgccgataca cccccaggcg
     7381 gaaatggcca ctcccaacac cggagtgcca cccatgatcc gcaccaccct gctcgccgct
     7441 gccctcgccc ttgccggcgt cgcgacgccg gcattcgccg ccgaggccga tgccggcgcc
     7501 gcgcccaccg tcatcctggt ccacggtgcc ttcgccgatg gctccagctg gaacaaggtc
     7561 atcaccaccc tgcatgactg gaaactgcct gcggtggccg tgcagaaccc gctcacctcg
     7621 ctggccgacg atgtggccgc cacccgtcgc gcgattgccg ccgcaccggg caaggtcgtg
     7681 ctggtcggcc acagctgggg cggcacggtc atcaccgaag cgggcaacga tcccaaggtg
     7741 caggcgctgg tgtacgtggc cgcattcgca ccggatgccg ggcagtcatc ggcacagcag
     7801 ggcgagggct atccggtcgg cccgggcctg acgcgcctgc aggagaagga cggctacctg
     7861 accctgccag ccgacgccat cgcccaggac ttcgcaccgg atgtgatgaa gaagaccgct
     7921 gcactgttgt acagcacgca ggtgccattg aaggccagcg cgctgggtga gtccgtcact
     7981 gtggccgcat ggcgcagcaa gccgagctgg tacgtgctca gccgtgacga ccgcatgttg
     8041 tcgccgcaac tgcaggcggc caccgcaaag cgcattggcg cgcagctgca attgatcggc
     8101 agcagccatg tgtcgctgct ctcgcacccg gctcaggtgg ctgacagcat tctggaggcc
     8161 gcaggcgtga agccggccga actgccgctg gccgagcagg gaggctgaac gatgggcgcg
     8221 ctgcgtgtgt atgtactgcc gttgctgctg ggcctgctgg gtggggcggc gctgctgatg
     8281 gccttgccca gcccggaggc cggtgcgcat ccggcgcagg ccgctcctgc tgccgggttc
     8341 gatggcggcg ggccctggca caacagccca ccgctcgcgt tgaatcaact gcgtgggcag
     8401 gtggtgctgg tcgagttctg gacctacgcc tgcagcaact gcctcaacgt ggcaccgcat
     8461 gtgcaccagt ggcatgcacg ttacgcgcgg cagggcctgc aggtgatcgg cgtgcatact
     8521 ccggagttcg cctacgaagg cctgcccggc aatgtgcgca aggccatcgc gcggctggat
     8581 atcacctggc cggtggtgca ggacaaccag taccggatct ggaacgcctg gggcaaccgc
     8641 ttctggccgg cgctttacct ggtcgaccgg cagggcaggg tggtctaccg ccactacggt
     8701 gaaggcgatt acgcacgtac cgaaagcgag atccagcgcc tgctggccag cccctgagcc
     8761 gcgctaccat ggccgcgccg cgcggccttg acctccgtct tcatcgagaa cgcaatgaac
     8821 cacgtaccgc acatccttgt cgtcgacgat gacagcgaga tccgccagat gctggccgac
     8881 tacctgcagc gcaacggcct gcgcgtcagc caggccgatg gcggccgtgc gatgcgcgcg
     8941 ctgatggaca cccacgcggt ggacctggtg gtgctggacg tgatgatgcc cggcgaggac
     9001 gggttgagcc tgtgccgcaa cctgcgtgcc ggcaagcatc gcgcggtgcc ggtggtgctg
     9061 ctgaccgccc gcgacgacga aaccgaccgc atcatcggcc ttgaaatggg cgccgatgac
     9121 tacgtgacca agccgttctc ctcacgcgaa ctgctggcgc gcatcaatgc ggtgatccgg
     9181 cgcacgcaga tgctgccgcc gaacctgcag gtgagtgaag ccggccgcca gttggccttc
     9241 ggcgactggc gcttggatac cactgcccgc catctgctgg atgcgcagga caccgcctat
     9301 ccgctcagcg gtgcggaatt ccgactgctg cgcgtgtttc tcgaccacgc caaccgtgtg
     9361 ctcagccgcg accagctgct cagccttacc cagggccgag atgcagaact gttcgatcgt
     9421 tccatcgatc tcctggtcag ccgcgtgcgc cagcgcctgg gcgatgacgc gcgtgagccc
     9481 acctacatca agaccgtgcg cagcgaaggc tacgtgttca gcgtgccggt gcagctgctg
     9541 gggccggagg aatgaacgcc cgcgcgcgcc gcctgccgtg gccgcgcacg ctgtcggcgc
     9601 gcctgctgct ggtgctgctg ggcggtttga tcctggccca tgcgctgtcc ttcggcctgt
     9661 tgttctacga acgctaccag tccacccgca gcatgatgct gcgcaacctg gacgaggatg
     9721 cagcagtgag cgtggccctg ctggaacacc tgccggccga ccagcgccag gcctgggtgc
     9781 cgcggttgga gcggcgcacg taccgttacc tgttgcgccc ggcacaggcc ggcccggcgt
     9841 tggaaaccga tcgtgcgcgc caggtcaccg ccatcatcga tgacagtctg gaacaccgct
     9901 atccgctgca ggcgcggcag gtggcacggc tgccggaacg ttttgaagtg gagctgcgcc
     9961 tgcacgacgg ttcaccgttg accatcgaag tcacaccgtc gggcctgccg ctggcgcgct
    10021 ggctgccggc cgtgctgctg gtgcagctgg ccctgctgct ggtatgcgcc tggctggcgg
    10081 tgcggctggc attgcgcccg ctgcggcagc tctcgcacgc cgtcgagcaa ctgcagcctg
    10141 gcaaggacgc accgatgctg cccgaagacg gccccgccga agtgggcacg gccgcagccg
    10201 cgctcaatgc actgcaggcg cggatccgtg gccatgtcag cgagcggctg cagattctgg
    10261 cggccatctc gcacgatctg cagacgccga tcacgcgcat gaagctgcgc gtggaaaccc
    10321 tgcccgaaga tgccacccag cagcgcctgc tggatgacct ggaccacctg gggcaactgg
    10381 tgcgcgaagg cgtggcctac gcgcgcagca gccacgtggc cagtggcgcg ccactggcga
    10441 tggatcttgg cgcgttcctg gccagcgtgg tgggcgacta tgaagacatg ggcaaggcgg
    10501 tcagtggtgg cgcacccaca ggcctgaccg tgcagacctg gccgcagccg ctgcggcggg
    10561 tggtcggcaa cctggtcgac aacgcgttgc gctacgccgg tagtgccgag atcgaggcgg
    10621 ggcgcgatgc agcaggccgg ccgtggatca gcgtgtccga ccgcggcccc ggcatcccgg
    10681 aggaccagct gcaggcggtg ctggcaccgt tccatcggct ggaaagctca cgcaaccgcg
    10741 ataccggcgg caccgggctg ggtctggcca tcgccgtgca gctggcgcag tcgctgggcg
    10801 gctcgctgcg gctgcacaac cgtgagggcg gtggcctgcg ggccga
//
