LOCUS       NZ_CP059405            22886 bp    DNA     circular CON 14-APR-2024
DEFINITION  Bacillus velezensis strain MV2 chromosome, complete genome.
ACCESSION   NZ_CP059405
VERSION     NZ_CP059405.1
KEYWORDS    RefSeq.
SOURCE      Bacillus velezensis
  ORGANISM  Bacillus velezensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus amyloliquefaciens group.
REFERENCE   1  (bases 1 to 4191702)
  AUTHORS   Chen,X.H., Koumoutsi,A., Scholz,R., Eisenreich,A., Schneider,K.,
            Heinemeyer,I., Morgenstern,B., Voss,B., Hess,W.R., Reva,O.,
            Junge,H., Voigt,B., Jungblut,P.R., Vater,J., Sussmuth,R.,
            Liesegang,H., Strittmatter,A., Gottschalk,G. and Borriss,R.
  TITLE     Comparative analysis of the complete genome sequence of the plant
            growth-promoting bacterium Bacillus amyloliquefaciens FZB42
  JOURNAL   Nat Biotechnol 25 (9), 1007-1014 (2007)
   PUBMED   17704766
REFERENCE   2  (bases 1 to 4191702)
  AUTHORS   Lee,H. and Jo,E.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUL-2020) Microbiology, Pusan National University, 2,
            Busandaehak-ro 63beon-gil, Geumjeong-gu, Busan 46241, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-JUL-2020
            Assembly Method                   :: HGAP v. 4.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 589.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013875015.1-RS_2024_04_14
            Annotation Date                   :: 04/14/2024 20:37:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,290
            CDSs (total)                      :: 4,172
            Genes (coding)                    :: 4,053
            CDSs (with protein)               :: 4,053
            Genes (RNA)                       :: 118
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 56 of 119
            Pseudo Genes (incomplete)         :: 72 of 119
            Pseudo Genes (internal stop)      :: 19 of 119
            Pseudo Genes (multiple problems)  :: 24 of 119
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:30:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3160399
            Orig. end                         :: 3183285
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP059405.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22886
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="11"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22886
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22886
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12886](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12886
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            603..1334
                     /locus_tag="H1Q60_RS16370"
                     /old_locus_tag="H1Q60_16370"
     CDS             603..1334
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417590.1"
                     /locus_tag="H1Q60_RS16370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16370"
                     /product="ABC transporter permease"
                     /protein_id="WP_017417590.1"
                     /transl_table=11
                     /translation="MSLLVRNEFLKLKRLKSIYVIFFLSFLPFLINGIGLLTMNENTDW
                     NKFYMFVFNQYSTLFPTIIFIFSGFYFYLEFKNRTMLNWMSYPYHKFKLILSKLAAAFL
                     FLFLISAVNHIIHLSTLFFFFREDISASDLLRLIATSFTSTTLSLLTIPIAALIAFLSK
                     NIVVVMITGVASFLIMTILLASDVSIAFPFSFIYRFSIQIFESDMGYSNSILLVWGLLI
                     MGLYVLVSLSGLYVYSKKNRM"
     gene            1352..1543
                     /locus_tag="H1Q60_RS16375"
                     /old_locus_tag="H1Q60_16375"
     CDS             1352..1543
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154894.1"
                     /locus_tag="H1Q60_RS16375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16375"
                     /product="hypothetical protein"
                     /protein_id="WP_003154894.1"
                     /transl_table=11
                     /translation="MEQVIFVISMLALGVTLVTFFGMILNDGLRGVLNFSRKPVKFMTG
                     SFLVYIVAFAVYILISVK"
     misc_feature    complement(1380..1395)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.85"
                     /tool="antismash"
     gene            1609..2859
                     /locus_tag="H1Q60_RS16380"
                     /old_locus_tag="H1Q60_16380"
     CDS             1609..2859
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154893.1"
                     /locus_tag="H1Q60_RS16380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16380"
                     /product="ATP-binding protein"
                     /protein_id="WP_025649633.1"
                     /transl_table=11
                     /translation="MKDNWVKLNIEQFARTFVFSLLLFFMLLLITDSQLQFKQYSLFFV
                     LSIFGSSCLCFTYDDRNKTYLRSLFRFSELCQEGSDADQLIKELTNEIQSVLLGKQIAL
                     INYDKKTLKLKGNHIQVPNINISNFKIGEIRETASGSILFIGEKCDTFVFIHLSHKGHP
                     IKIRENEADWLRMLAFCTASALQNKLLIQKKIDEIIIDDQHKCKSAVLSKVLFSISEIE
                     RTKLAQDIHDSIIQELIFVCRELEYHVEKYKDIYYIREILLDNIQYIREKCFDLRPPFL
                     MEMGLLRSIQVLIDKHKSNYQLDIEFFVDVKDDSIFTEDITINFYRIVQELLTNAVKHS
                     KASYIVLTMIQKKTSLMFVYEDNGIGIDWNKVNSKTNSFGLTGIKERINCMSGIHNISS
                     GVNEGLLLRFEISTKNE"
     misc_feature    complement(1651..1664)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 22.07"
                     /tool="antismash"
     gene            2871..3536
                     /locus_tag="H1Q60_RS16385"
                     /old_locus_tag="H1Q60_16385"
     CDS             2871..3536
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154892.1"
                     /locus_tag="H1Q60_RS16385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16385"
                     /product="response regulator transcription factor"
                     /protein_id="WP_025649634.1"
                     /transl_table=11
                     /translation="MIKILLIDDHIGVAQGTKAILEKSNKMGVTILSCCKEVLNHLKHY
                     EYDLLLLDLYMPELNGMELSKMILRESPDQKIIIYTGFDISVHFNLLVEVGVSGFISKS
                     STEEHMIKVIESVIEGDTIIPTHLFKQLRRTEANTFNIDKLEDTIRDITLNEREQDILA
                     GVAEGMTNRELSAKLLISQRAVEYILTGVYNKLGVKSRTEALIKANRYSLISMKTIYE"
     misc_feature    complement(3552..3566)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.27"
                     /tool="antismash"
     gene            3729..3911
                     /locus_tag="H1Q60_RS16390"
                     /old_locus_tag="H1Q60_16390"
     CDS             3729..3911
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154891.1"
                     /locus_tag="H1Q60_RS16390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16390"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_003154891.1"
                     /transl_table=11
                     /translation="MNEKMYRFAGDLREELEEISLSEFSGGGGAEQRGISQGNDGKLCT
                     LTWECGLCPTHTCWC"
     CDS_motif       3729..3794
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNEKMYRFAGDLREELEEISLS"
                     /locus_tag="H1Q60_RS16390_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       3795..3911
                     /prepeptide="core"
                     /locus_tag="H1Q60_RS16390_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.60"
                     /molecular_weight="3895.3"
                     /monoisotopic_mass="3892.7"
                     /core_sequence="EFSGGGGAEQRGISQGNDGKLCTLTWECGLCPTHTCWC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEKMYRFAGDLREELEEISLS"
                     /leader_location="[3728:3794](+)"
                     /alternative_weights="3913.3"
     misc_feature    complement(4102..4116)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.95"
                     /tool="antismash"
     gene            4289..>7065
                     /gene="lanM"
                     /locus_tag="H1Q60_RS16395"
                     /old_locus_tag="H1Q60_16395"
                     /pseudo=""
     CDS             4289..>7065
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="H1Q60_RS16395"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="H1Q60_16395"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /pseudo=""
                     /sec_met_domain="DUF4135 (E-value: 3.8e-83, bitscore:
                     277.7, seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFHVFALKVSSYFNDLLKKSKFPSYDYLLEQPALFHHCISNQLEK
                     IILKVSYRTLVLDMNMNREKGFLAGETPKEKYGYYNKTLLCSPEYLESFFQQYPVLLRV
                     IGNELRKFKKFILEFISRFEKDKPELLSLFGFSEQVKIRDIEVGMGDSHSDGRKVTKIT
                     LNEGKLIYKPRSLEIDLLYKKIIEFLNEKIRDHDIKLSTPNVLSRDGYGWTEFISFKAC
                     NCLKDVQNFYQRTGAQIGLLYALKAVDFHSENLIANGSYPVLIDLESLFHPAYQKKKDG
                     MDAYEKAETQLHKSVRALGLLPFFFAGKADISGIGRKGKAKSIIKVPQLINLKTAEMSV
                     KRDYVEIDTANNHPMLENKFVYAKDYVEELKQGFSKAYMTILKHASELIRIIEKSENKI
                     YVRFISKPTIKYSAY"
     gene            7169..9316
                     /locus_tag="H1Q60_RS16400"
                     /old_locus_tag="H1Q60_16400"
     CDS             7169..9316
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154889.1"
                     /locus_tag="H1Q60_RS16400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16400"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_017417594.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.3e-26, bitscore:
                     90.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIRKRKLPVILQRNQFDCGITCLAMVLSRAEGIKINPNKLKLNK
                     EIIGRDGTDLIEMKRISETFDYDFKAFRTDNITQLKELNKNHPLIVHWNHNHFVVVDAF
                     GTDNVKIIDPSSGRLTITLEEFKTFYNGISIMLIRKNEIERKDKTASSLKDVSSFRKIG
                     KYLLKDKKLLGVIISFTFIFQALNLMTPFLTQYIIDSFIDGNEKILPIPMLFMIVIVSI
                     ALFFSLSLLRMKFIIKLQLKINKSMTDKIIHKIFSLPLKFFEANTAGDISTRIHNIAVI
                     REVISRLASTLILDISLIFVFFIVMFVYSPILSFIVLLGAAIQVMSTKILLPKIEMFTK
                     QEVNSQSNFQSQLIEILRSMTFIKTIGETRNIESQLNYNFNHQLDYFSKRMNYSSLLGA
                     VSNAINLSLPLFILIVGTWSAVSIGLTLGAVIAFSNIAGRFMSPLGSIIGSLESIKLVE
                     EMVDRVEAVLDEKDEEVNDKSSELFNPAAHNISLKNIDFSYNGNDYILNNINFMIRPRE
                     KITLIGKTGSGKSTLIKIIAGLYQKTAGEICYGEFKIEDVNMVKLRETLGYIVQDVNLF
                     NDTIINNIKYFNEKITMEEVVQAAKEACIHEDIIKMPMGYHTMIGENGITLSGGQRQRI
                     SIARVLAKNPQILFIDEGTSNLDKDTELNILNNIYKKDITVISITHRTEWLEFSESVYE
                     IENGNLKTIKAKYESQLQQTY"
     CDS             9318..9500
                     /gene="allorf_3169717_3169899"
                     /locus_tag="allorf_3169717_3169899"
                     /protein_id="allorf_3169717_3169899"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MKGGEIWNMKKNFSALYETSEQELKELVGGQNSVSITTYPITNHI
                     CPTITVGCACPQRQV"
     CDS_motif       9318..9407
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKGGEIWNMKKNFSALYETSEQELKELVGG"
                     /locus_tag="allorf_3169717_3169899_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9408..9500
                     /prepeptide="core"
                     /locus_tag="allorf_3169717_3169899_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.00"
                     /molecular_weight="3119.6"
                     /monoisotopic_mass="3117.6"
                     /core_sequence="QNSVSITTYPITNHICPTITVGCACPQRQV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKGGEIWNMKKNFSALYETSEQELKELVGG"
                     /leader_location="[9317:9407](+)"
                     /alternative_weights="3137.6"
                     /alternative_weights="3155.6"
                     /alternative_weights="3173.6"
                     /alternative_weights="3191.6"
     misc_feature    complement(9343..9357)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.96"
                     /tool="antismash"
     gene            9523..9699
                     /locus_tag="H1Q60_RS16405"
                     /old_locus_tag="H1Q60_16405"
     CDS             9523..9699
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417595.1"
                     /locus_tag="H1Q60_RS16405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16405"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_017417595.1"
                     /transl_table=11
                     /translation="MKKEFLALELMTEEELKELAGGSEATPMTVTPTTITIPISLAGCP
                     TTKCASIVSPCND"
     CDS_motif       9523..9588
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKEFLALELMTEEELKELAGG"
                     /locus_tag="H1Q60_RS16405_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9589..9699
                     /prepeptide="core"
                     /locus_tag="H1Q60_RS16405_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.30"
                     /molecular_weight="3405.9"
                     /monoisotopic_mass="3403.7"
                     /core_sequence="SEATPMTVTPTTITIPISLAGCPTTKCASIVSPCND"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKEFLALELMTEEELKELAGG"
                     /leader_location="[9522:9588](+)"
                     /alternative_weights="3423.9"
                     /alternative_weights="3442.0"
                     /alternative_weights="3460.0"
                     /alternative_weights="3478.0"
                     /alternative_weights="3496.0"
                     /alternative_weights="3514.0"
                     /alternative_weights="3532.1"
                     /alternative_weights="3550.1"
                     /alternative_weights="3568.1"
     gene            9736..9912
                     /locus_tag="H1Q60_RS16410"
                     /old_locus_tag="H1Q60_16410"
     CDS             9736..9912
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417595.1"
                     /locus_tag="H1Q60_RS16410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16410"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_017417596.1"
                     /transl_table=11
                     /translation="MKKDFQALTPMTEEELKNLAGGSDATPMTVTPTTITIPISLAGCP
                     TTKCASIVSPCND"
     CDS_motif       9736..9801
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKDFQALTPMTEEELKNLAGG"
                     /locus_tag="H1Q60_RS16410_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9802..9912
                     /prepeptide="core"
                     /locus_tag="H1Q60_RS16410_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.30"
                     /molecular_weight="3391.9"
                     /monoisotopic_mass="3389.7"
                     /core_sequence="SDATPMTVTPTTITIPISLAGCPTTKCASIVSPCND"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKDFQALTPMTEEELKNLAGG"
                     /leader_location="[9735:9801](+)"
                     /alternative_weights="3409.9"
                     /alternative_weights="3427.9"
                     /alternative_weights="3446.0"
                     /alternative_weights="3464.0"
                     /alternative_weights="3482.0"
                     /alternative_weights="3500.0"
                     /alternative_weights="3518.0"
                     /alternative_weights="3536.1"
                     /alternative_weights="3554.1"
     gene            10001..12886
                     /locus_tag="H1Q60_RS16415"
                     /old_locus_tag="H1Q60_16415"
     CDS             10001..12886
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154888.1"
                     /locus_tag="H1Q60_RS16415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16415"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_025649635.1"
                     /sec_met_domain="DUF4135 (E-value: 2.3e-85, bitscore:
                     285.0, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.1e-54, bitscore:
                     182.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTQNSDNYVYENSMLNVFKEEDYFEGFAQYYISIFKAQIVKEI
                     DRIPSESLLDKGCLVESILINYKKKIYYLAGKTLIHEFHQTFDEFDQKNESKNYDIFSE
                     RLKNSAFVEEILNNYPVLQGLISRSTSDFIRFTISIIKHWVNDYKKIQQKFNLSFGKMR
                     KINMNAGDVHNGGKSVVIIEFENNKLVYKPRSLEIDVFYEKVIDYVNQYYQTNLKTPLS
                     LDQGEYGWQEYVQSEPCDNIEQVRNYYYQFGMHLGFIYAFQGSDFHFENIIACRDKPVL
                     VDLETLFQSSLFFSEENKENVNLMASAQVNKTILKSALFNYMSFPEDNGLTNIGGLINT
                     ENQKGEKEEVLHIKTDKISMRKKQYLFKRGRNLPVYKNKVAECFEFEREFIEGFKRIYF
                     ILKEDLYIRNLIRDLNYAPIRIIVRPTYVYASFLETLLHPMYLKDYGERIRVLSFIKDA
                     YTKYEVFDSISPFEIKDMMIGDIPYFNAPISEKRVYSNSIHVVDTGIMKQSAKQEVLTR
                     LANMSEEDMHQQVSLINMALSSTAANLDIIYKNQIDDFVPGYFKNDIQIKELIQIETDC
                     ILKQAIESEKYLQWVSIVSAPNGTLSVGPLSFGLYDGLAGVGLYFSAYDFIYNDEKVKS
                     VLRKIVNSINQIYEHSIYKTNFSAFYGSSSYIYFVNKMRDTGLYSENEVNSMCKAYLEK
                     LRQETGQITHTDFIGGLAGILKVVIQLGRYHRTELMEDTARAVCKEICKRAIQNRNEAY
                     WKSDADENIVLAGFSHGITGICYALSEYYAHIEASGEVLRLIESALKYEDKFFDIKINK
                     WRDNRKNELDYSSAMWCHGSCGILLGRSRIYENVDGRIHVGYINESLDDTLLNGNFHRQ
                     GYSLCHGTMGNIDVLHAIKELSLFKNRKQEIENTINIWVNHFKETLLKNGWQNGIRNDH
                     SGLGMMLGKTGQLYALLRLVNKEIPTPLALD"
     gene            complement(12933..13697)
                     /locus_tag="H1Q60_RS16420"
                     /old_locus_tag="H1Q60_16420"
     CDS             complement(12933..13697)
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389122.1"
                     /locus_tag="H1Q60_RS16420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16420"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_025649636.1"
                     /transl_table=11
                     /translation="MTVSIVFMGFFVGTLVGLTGVGGAALLTPLLIVLGINPSIAVGTD
                     LLYNSITKLFGVVSHWKQRTVQFKLVGYLALGSIPSATAAIGILHLFPAFHQHQEQIIK
                     QALGYVLTLVAISIIARLFFDKKLRPNRWQQKTLEEKRTLMILIGVIFGFIVGLTSIGS
                     GSLFAIAMLYLFRMKTAEVVGTDIAHAFLLVTAAGLLNASFGSVDYLLVLNLLIGSVPG
                     VLLGSFFSPKFSPRPLQFVMAAIILISGIKLI"
     misc_feature    complement(13767..13781)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 25.28"
                     /tool="antismash"
     gene            complement(13846..14313)
                     /locus_tag="H1Q60_RS16425"
                     /old_locus_tag="H1Q60_16425"
     CDS             complement(13846..14313)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417598.1"
                     /locus_tag="H1Q60_RS16425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16425"
                     /product="DinB family protein"
                     /protein_id="WP_017417598.1"
                     /transl_table=11
                     /translation="MTAQNQLVSHFLSHRNVTIELAEKISREHYDYKPAETSMSAQELV
                     KHIVYSFLMFANVINDGNGSAIQNKPKEEAETDLVKLAEACTEKTTNILSQLTEEQLNR
                     EIDLTASFGRKITGAALLQLAMEHEIHHKGNLFVYVREMGHTELPFYQQKS"
     gene            14518..15654
                     /locus_tag="H1Q60_RS16430"
                     /old_locus_tag="H1Q60_16430"
     CDS             14518..15654
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389125.1"
                     /locus_tag="H1Q60_RS16430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16430"
                     /product="Rap family tetratricopeptide repeat protein"
                     /protein_id="WP_087920760.1"
                     /transl_table=11
                     /translation="MRMKQTIPSSFVGLKINEWYTHIRQFHVLEAERVKREVEREIEDM
                     EEDQDLLLYYSLMEFRHRVMLDYIKPLKEDPSQPEFSELLEDIEGNQYKLTGLLDYYFN
                     FFRGMYEFKQKMFLNAMMYYKRAEKNLALVSDDIEKAEFAFKMAEIFYNLKQTYVSMSY
                     AVQALETYQSYETYNVRRIQCEFVIAGNYDDMQYPERALPHLELALDLAKQEGNPRLIS
                     SALYNLGNCYEKMGDLSKAAEYFETSVSICRSEKFDNLPHSIYSLTQVLYKQNTTAEAE
                     KQYRLGLSIAREYNDELFVNLFQFLHALYGKEMDNASVRHTFDFLEEHMLYPYVEELAH
                     DAAKFYMKHGQPEKALTFYEKMVHAQKQIQRGDCLYEI"
     gene            15644..15778
                     /locus_tag="H1Q60_RS16435"
                     /old_locus_tag="H1Q60_16435"
     CDS             15644..15778
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012117358.1"
                     /locus_tag="H1Q60_RS16435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16435"
                     /product="PhrA family phosphatase inhibitor"
                     /protein_id="WP_003154881.1"
                     /transl_table=11
                     /translation="MKSKLLSGLLLVAVGFSFTQVIGHESHLENQADGTFHIAARNQT"
     misc_feature    complement(15813..15826)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.57"
                     /tool="antismash"
     CDS             15816..15893
                     /gene="allorf_3176215_3176292"
                     /locus_tag="allorf_3176215_3176292"
                     /protein_id="allorf_3176215_3176292"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRIHSIFIRMQGLYAQVICPTNATY"
     CDS_motif       15816..15860
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRIHSIFIRMQGLYA"
                     /locus_tag="allorf_3176215_3176292_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       15861..15893
                     /prepeptide="core"
                     /locus_tag="allorf_3176215_3176292_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.60"
                     /molecular_weight="1073.2"
                     /monoisotopic_mass="1072.5"
                     /core_sequence="QVICPTNATY"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRIHSIFIRMQGLYA"
                     /leader_location="[15815:15860](+)"
                     /alternative_weights="1091.2"
     gene            15921..16874
                     /locus_tag="H1Q60_RS16440"
                     /old_locus_tag="H1Q60_16440"
     CDS             15921..16874
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389128.1"
                     /locus_tag="H1Q60_RS16440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16440"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_065180405.1"
                     /transl_table=11
                     /translation="MGIEVKKRLVSADKYALKCPNPMTPEYITIHNTANDASAANEISY
                     MTGNSESTSYHFAVDDKEVIQGIPLDRNAWHSGDGTNGTGNRKSIAIEICYSKSGGERY
                     RAAEELAIAFAAQLLKERGWGIDRIRKHQDWNGKYCPHRILSEGRWDEVKAKIAKKLSG
                     SMPAKKASISSSASEYHVKKGDTLSEIAASHGVSVKSLQSINHITDPNHITVGQVIKLA
                     QTGSSSKSQAVPSYPLPSGVIKVTKPLTKGTNVKQVQNALSALYFYPDKGAKNHGTDGV
                     YGPKTANAVKRFQSVSGLTADGIYGPKTKAKIEEKL"
     gene            complement(16912..17289)
                     /locus_tag="H1Q60_RS16445"
                     /old_locus_tag="H1Q60_16445"
     CDS             complement(16912..17289)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389129.1"
                     /locus_tag="H1Q60_RS16445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16445"
                     /product="PH domain-containing protein"
                     /protein_id="WP_017417600.1"
                     /transl_table=11
                     /translation="MGFINGLLGNASTISTAEAKEELARILLEGENVNAAFKLVRDIIV
                     FTDKRLILVDKQGLTGKKTEIQSIPYKSISRFSVETAGRFDLDSELKIWISGAELPAVS
                     KQFKKDESIYDIQKALAAVCM"
     gene            17399..18004
                     /locus_tag="H1Q60_RS16450"
                     /old_locus_tag="H1Q60_16450"
     CDS             17399..18004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014417516.1"
                     /locus_tag="H1Q60_RS16450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16450"
                     /product="poly-gamma-glutamate hydrolase family protein"
                     /protein_id="WP_017417601.1"
                     /transl_table=11
                     /translation="MKDRYDNFAALSAAESEYRIIYEEKEGSKCIVLAPHGGRIEPGVS
                     ELVRAFSDQSSIYLFEGTKRCNNRSLHLTSTRFDEPLALEKVTAHHYGLAFHGYHDLKK
                     ANTLVGGADLEKARLICDLLREAGFDAELTEKNDRLAGVNPGNIVNRTKRKMGLQLEVS
                     TAQRHALFSNFGCRGEKYTPTDLFFRYVEAVKAGFYDK"
     CDS             18001..18162
                     /gene="allorf_3178400_3178561"
                     /locus_tag="allorf_3178400_3178561"
                     /protein_id="allorf_3178400_3178561"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MNRGARFYIHWSYAAQEVLGGQHGENSVMMQKPFLRFKMMTFCRL
                     RFKPAENR"
     CDS_motif       18001..18063
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNRGARFYIHWSYAAQEVLGG"
                     /locus_tag="allorf_3178400_3178561_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       18064..18162
                     /prepeptide="core"
                     /locus_tag="allorf_3178400_3178561_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.00"
                     /molecular_weight="3923.7"
                     /monoisotopic_mass="3921.0"
                     /core_sequence="QHGENSVMMQKPFLRFKMMTFCRLRFKPAENR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNRGARFYIHWSYAAQEVLGG"
                     /leader_location="[18000:18063](+)"
                     /alternative_weights="3941.7"
     gene            complement(18159..18749)
                     /locus_tag="H1Q60_RS16455"
                     /old_locus_tag="H1Q60_16455"
     CDS             complement(18159..18749)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016936463.1"
                     /locus_tag="H1Q60_RS16455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16455"
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="WP_003154873.1"
                     /transl_table=11
                     /translation="MGDFLTHLEEYVKNLYCRMGMTAPLHIDMQMIAKELDIWIHFEDT
                     HSMMLKRDGMYSIVLNQKKSPEEQWQDFAHELCHVLKHTGNHFHMNKLFRELQEFQANH
                     FMYHFCVPTFMLLNMELPQRRSHAVILIAAAFRVTASFAEKRLELFERRKAGIQFQKRL
                     ACLLSDKRPNVYYGSGQTHLHAAEEKTPYFIEN"
     misc_feature    18764..18779
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.99"
                     /tool="antismash"
     misc_feature    complement(18765..18778)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 24.65"
                     /tool="antismash"
     misc_feature    complement(18828..18841)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.38"
                     /tool="antismash"
     gene            complement(18898..19236)
                     /gene="xre"
                     /locus_tag="H1Q60_RS16460"
                     /old_locus_tag="H1Q60_16460"
     CDS             complement(18898..19236)
                     /codon_start=1
                     /function="16.3: Control16.5: Explore"
                     /gene="xre"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389133.1"
                     /locus_tag="H1Q60_RS16460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16460"
                     /product="HTH-type transcriptional regulator Xre"
                     /protein_id="WP_013351934.1"
                     /transl_table=11
                     /translation="MIGGRLKSLRGKKTQEEVANHIGVSRARYSHYENGRSEPDYETLQ
                     KLADYFNVSTDYLLTGKEPSDEDLFADPDLQIAYRDMQDFSPESKQQAIEFINYLKEKE
                     KNRRPKHK"
     gene            19427..19606
                     /locus_tag="H1Q60_RS16465"
                     /old_locus_tag="H1Q60_16465"
     CDS             19427..19606
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154869.1"
                     /locus_tag="H1Q60_RS16465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16465"
                     /product="hypothetical protein"
                     /protein_id="WP_014417518.1"
                     /transl_table=11
                     /translation="MQPIIIRFSSNPADQRCLGKAGGSISFTACGLPVFRFDNRLQYER
                     YISLKKNGDVQYES"
     gene            19596..20423
                     /locus_tag="H1Q60_RS16470"
                     /old_locus_tag="H1Q60_16470"
     CDS             19596..20423
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417603.1"
                     /locus_tag="H1Q60_RS16470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16470"
                     /product="phage portal protein"
                     /protein_id="WP_017417603.1"
                     /transl_table=11
                     /translation="MNRKSYPFFIYSGLLNSEHYEKIGSAIWLFLWFISSTTKEHVKDG
                     VKWGIVLGHKPVKAKEMADVFAVSEKTVRRWLEVLEQHEYIKTVRAPYGLIVSIKHSKR
                     FTPKKTLTRPEVTDRTISADHRDKNVRREIDITKNHTAEEAINDIAAHFIRLRSAQEGR
                     SVYPSPRDYQAIARIVSLGASAQEAIKWLGECFTAFEQRRTSSAETIKAFSYCAKYMED
                     RLNARIAGRTITTKKERNTIHDKTNDRADTGRPEKRKTSITGGQTGRIRRKPL"
     gene            20323..21123
                     /locus_tag="H1Q60_RS16475"
                     /old_locus_tag="H1Q60_16475"
     CDS             20323..21123
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007407283.1"
                     /locus_tag="H1Q60_RS16475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16475"
                     /product="ATP-binding protein"
                     /protein_id="WP_017417604.1"
                     /transl_table=11
                     /translation="MTKRTIEQILADLKNGKRPLLADRPEESDESRFDCPLCKDQGGYL
                     KNQLGMDVWVKCRCAAERKAERILSASEITDAFRKLDFKGFITRGKPQAVVDAYECALE
                     YVENFDKMKNCRKNSIALLGRPGSGKTHLLTALSNYVMRQKQTPVLYFPFVEGFTDLKN
                     DFDLLDAKLGRMKQADVLFIDDLFKPLNGKPRATDWQIEQMYAVVNYRYLNHKPVLISS
                     ELACDGLVQVDEALGTRIYEMCSDYLVIINGNSFDVNHRLEGAR"
     gene            21123..21290
                     /locus_tag="H1Q60_RS16480"
                     /old_locus_tag="H1Q60_16480"
     CDS             21123..21290
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154863.1"
                     /locus_tag="H1Q60_RS16480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16480"
                     /product="hypothetical protein"
                     /protein_id="WP_003154863.1"
                     /transl_table=11
                     /translation="MCKLCGPKKVIVTETGFGAVFHPCPNCKTGTDLTPVIKRLERMVQ
                     DAKARLDARV"
     CDS_motif       21123..21179
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MCKLCGPKKVIVTETGFGA"
                     /locus_tag="H1Q60_RS16480_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       21180..21290
                     /prepeptide="core"
                     /locus_tag="H1Q60_RS16480_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="4025.7"
                     /monoisotopic_mass="4023.2"
                     /core_sequence="VFHPCPNCKTGTDLTPVIKRLERMVQDAKARLDARV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MCKLCGPKKVIVTETGFGA"
                     /leader_location="[21122:21179](+)"
                     /alternative_weights="4043.7"
     gene            21388..21729
                     /locus_tag="H1Q60_RS16485"
                     /old_locus_tag="H1Q60_16485"
     CDS             21388..21729
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015239676.1"
                     /locus_tag="H1Q60_RS16485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16485"
                     /product="hypothetical protein"
                     /protein_id="WP_039251797.1"
                     /transl_table=11
                     /translation="MQEKHSPAPWRAVHSGEEKPIYIYSAYSEADKEKFPYSNGRLIAA
                     VFNLSSYSQQINAALMAKAPELFEAAETALRLLRGESSEEKEAFINKLGSLIHEVNILK
                     KTEDVKHES"
     gene            21719..21922
                     /locus_tag="H1Q60_RS16490"
                     /old_locus_tag="H1Q60_16490"
     CDS             21719..21922
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016936455.1"
                     /locus_tag="H1Q60_RS16490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16490"
                     /product="XtrA/YqaO family protein"
                     /protein_id="WP_003154859.1"
                     /transl_table=11
                     /translation="MNPKKLTDIEHTTLKSQLEEGKVRVIIVDGLKKEAWLAEAPEHGK
                     TLVETRKGDLARVEYEIGFKLN"
     gene            22028..22540
                     /locus_tag="H1Q60_RS16495"
                     /old_locus_tag="H1Q60_16495"
     CDS             22028..22540
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154857.1"
                     /locus_tag="H1Q60_RS16495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H1Q60_16495"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_012117362.1"
                     /transl_table=11
                     /translation="MEDLLFEYKRTLKETKKWYKQLEEADETVLTSEELKDKKIIRTII
                     TDVEYVIEWLEKGRQPGIRRAIDRRDAYQRMLIKDPRIIETYSQALMFEPSANVTEEDR
                     IRLRDALAVLTDREKEMLLLHKAECFSYERIAALLNVKKSTVQTTVKRALLKIQKQQEQ
                     RNQSPAS"
     CDS             22542..22643
                     /gene="allorf_3182941_3183042"
                     /locus_tag="allorf_3182941_3183042"
                     /protein_id="allorf_3182941_3183042"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSYVCHLEVNRRSQKAARLEAAFYYRQSCRRWR"
     CDS_motif       22542..22607
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSYVCHLEVNRRSQKAARLEAA"
                     /locus_tag="allorf_3182941_3183042_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       22608..22643
                     /prepeptide="core"
                     /locus_tag="allorf_3182941_3183042_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.60"
                     /molecular_weight="1602.8"
                     /monoisotopic_mass="1601.8"
                     /core_sequence="FYYRQSCRRWR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSYVCHLEVNRRSQKAARLEAA"
                     /leader_location="[22541:22607](+)"
     misc_feature    22660..22675
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.13"
                     /tool="antismash"
     misc_feature    22851..22862
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
ORIGIN
        1 tcttaactat ttaaaaaaat cagcttctga tgaagaaata aatgagattt taggaaaggt
       61 tggacttttt gaacataaag ataagctgtt ttcgcaaact tcattaggaa tgaaacagag
      121 gttgggaatt gccagagcag ttgcgcatgc tcctgcattg cttttgctgg atgagccgac
      181 gaacggttta gatccatatg gtattaaaga agtacgtgaa atgctgatcc aagaagtaat
      241 gaaaaatgga accacagtcg ttatttcaag tcacctttta agtgagatta atctcatggc
      301 cgatgaattg cttattatga ataaggggca gattattttc gagtcagcct ttatgaaaaa
      361 tacgcaacat ctttatttat acaaaattcc agctgaagcg ggtattaatt gggcggatat
      421 tgagaaattt gcggatcatg ttatttcaaa gaataaacag caattcgagt ttatttcagt
      481 aattcacccg tcggaaatga aagagaaatt aaattcttgt ggatttaaca aggcacctat
      541 tgacggattt aagctatctt tggaagatct ttatttaaaa ctgctggcaa aggagaaagg
      601 tcatgagtct gttagtgcgt aacgagtttc taaaacttaa aagactgaaa tcaatttatg
      661 ttattttctt tctaagcttt ttgccatttc tcataaacgg gatcggtctt ttgactatga
      721 acgaaaatac agattggaac aaattttata tgtttgtttt taatcagtat tcgaccctat
      781 ttccgactat tatttttatt ttttcaggtt tttattttta tttagaattt aaaaacagga
      841 caatgctgaa ttggatgtca tatccgtatc ataaattcaa attgatatta tcaaagctag
      901 ctgcagcttt tctatttttg tttttaattt cagctgttaa tcatattatt cacttatcca
      961 ccttgttttt cttttttcgg gaagatatct cagcaagcga cttattaaga ttaatagcga
     1021 cttcttttac ttctactact ttgagcctgc taaccattcc gattgcagct ttaattgctt
     1081 ttttaagtaa aaatatagtg gttgtcatga taaccggtgt agcttccttt ttaataatga
     1141 cgatactgtt agcaagtgat gtctcaatag cctttccttt ttcttttatt tatcgtttca
     1201 gtattcaaat ttttgaaagt gatatgggat attccaattc aattctttta gtttggggat
     1261 tactgatcat ggggctgtat gttttggtgt ccttatcagg attatacgta tattcgaaaa
     1321 aaaacagaat gtaaatggag gatgagtata catggagcaa gttatttttg tgatttcaat
     1381 gctcgcttta ggagttacac tggttacctt tttcggaatg attttgaatg acggattaag
     1441 aggcgtacta aacttttcaa gaaaacctgt aaaatttatg actggatcat ttctggtata
     1501 cattgttgcc tttgctgttt atattttaat aagtgtaaag taactttttc attttaaggg
     1561 gattcaaagg gattccctta ttttccttag taaggggctt ggatacaaat gaaagataat
     1621 tgggtgaagc ttaatattga gcagtttgca agaacttttg ttttctcctt attattgttt
     1681 tttatgcttt tgcttataac agacagccaa ttacagttta aacagtatag tctatttttt
     1741 gttctaagta tattcggcag tagttgttta tgctttacct atgatgacag aaataagaca
     1801 tatcttcgca gcctgttccg tttttcagaa ttatgtcaag agggatccga tgcagatcaa
     1861 ttgataaaag aactaaccaa tgaaatacag agtgtgctct taggaaagca gattgctctt
     1921 ataaactatg acaaaaaaac attaaaattg aaaggaaatc acattcaggt tcctaacata
     1981 aacatttcaa attttaagat aggagaaata cgtgaaaccg ccagcggatc aattctgttt
     2041 atcggggaga agtgtgatac atttgttttt attcatttat cacataaagg acaccctata
     2101 aagattcgtg aaaacgaagc agattggctg cgaatgctgg cattctgcac agcatctgca
     2161 cttcagaaca aattattgat tcaaaaaaaa attgatgaaa ttatcataga cgatcaacat
     2221 aaatgtaagt cggctgtact ttctaaggtt ttattttcta tttcagaaat agagagaacc
     2281 aagcttgcac aggatattca tgactctatc attcaagagc tgatatttgt atgcagagaa
     2341 ttagagtatc atgttgagaa atacaaggat atttattaca taagagaaat tttgctggac
     2401 aatatccagt atataagaga aaaatgtttt gatttaagac cacctttttt aatggagatg
     2461 ggacttcttc gaagcattca agtcctgatt gataaacata aaagcaacta tcagcttgat
     2521 attgaatttt ttgtagatgt aaaagatgat tctattttta cagaagatat cacaataaac
     2581 ttttaccgga ttgttcaaga actgcttact aatgctgtta aacactcaaa agccagttat
     2641 attgttttga cgatgattca aaaaaaaaca agtcttatgt ttgtttacga agataatgga
     2701 atcggcattg attggaataa agtaaattca aaaacaaaca gttttgggct gacagggatc
     2761 aaagagcgta taaattgtat gagtggtatt cataatatat cttcaggcgt aaatgaagga
     2821 ttgctgttaa ggtttgaaat aagtacgaaa aatgaatagg gagcgctgac atgataaaga
     2881 ttctattaat tgatgatcat attggtgttg ctcaagggac aaaagccatt cttgaaaaaa
     2941 gcaataaaat gggagtaaca atattgtctt gctgtaaaga agtacttaat caccttaagc
     3001 attacgagta tgacttactt ttacttgatt tatatatgcc ggagttaaat ggaatggaat
     3061 tgtcaaaaat gattcttaga gagagtcccg atcaaaaaat tataatttat actggttttg
     3121 atatctctgt ccatttcaat cttttggttg aagttggtgt ttccgggttc ataagtaagt
     3181 cttcaacaga agagcatatg ataaaagtaa ttgaaagtgt cattgaagga gataccatta
     3241 ttcctaccca tctctttaaa caattaagaa gaacagaagc aaatacgttc aacattgata
     3301 agcttgaaga tacaataaga gatattactt taaatgaaag agaacaagat atcttagcgg
     3361 gcgtagcgga gggaatgaca aaccgggaat tatcagcaaa gctgttgatc agtcaaagag
     3421 cggttgaata cattcttact ggtgtgtaca acaagctcgg agtaaaatcc agaacagagg
     3481 cactgatcaa agcaaatcga tattcattaa tttctatgaa aactatatat gagtaaatga
     3541 atcgggatta acggaacagt taatcccgat tttctttata acctatactt cggaaacgcg
     3601 caaaaaaaaa gcgcttttcc gaatatgact tttcggtgcc tataggtaaa agatcgttta
     3661 tcatagattt atagaaatat atggattcag atccaatata tttcaaaaac tcaaggggag
     3721 gaatattaat gaatgagaaa atgtatcgtt ttgccggtga tttaagagaa gaacttgagg
     3781 aaatttcttt aagtgaattc agcggaggag gaggcgcaga acagcggggg atttctcaag
     3841 gaaatgatgg taagctttgt acgttaactt gggaatgcgg tctttgtcct actcacactt
     3901 gctggtgtta aaacaaatcc gaaaataaga aaatagattt ccaatgctct gggagatcca
     3961 gctgtctccc tcttttttaa aaggagatga atattaaatg aattcgctga ctaatattct
     4021 attaagtaaa gaaaaaaaag ctgctgtctc tcaatttgat gaaaatgaga atctgtttga
     4081 tcgaaactta gaattaatct ataagaatga tattcaaatg gcccaggaaa gcattcataa
     4141 tgtgttatcc attcaatcaa ttgataaagt gaaaaactta tatcaaaccc ccctacataa
     4201 atccgctttt acagttcatg ttttcgaaaa cctaaaaaaa gggatcgctc accaagctat
     4261 taaaaaagaa gacgtaaatg aagaaatcat gtttcacgtt tttgcgttaa aagtgtcctc
     4321 ttacttcaat gatctactta aaaaatcaaa gtttccttct tatgactatc tgctggaaca
     4381 accggctctt tttcatcatt gtatttcaaa tcaattagaa aaaatcattt taaaagtctc
     4441 ctatagaaca cttgtattgg atatgaatat gaatcgggaa aaaggttttt tggcagggga
     4501 gactcctaaa gaaaaatatg gttattataa taaaactctt ttgtgcagtc cggagtatct
     4561 cgagagtttt ttccaacaat atccagtatt attaagagtg atcggaaatg aactgagaaa
     4621 atttaaaaaa ttcatactgg aatttatctc ccgttttgaa aaggacaagc ctgaactgct
     4681 ctctttattt ggtttttcag aacaagtcaa aataagggac attgaagtag ggatgggtga
     4741 ttctcattct gatgggagaa aggttactaa aataacatta aatgaaggca aacttattta
     4801 taagccgaga agtttagaaa ttgatctatt atataaaaag ataattgaat ttttgaatga
     4861 gaaaattaga gatcatgata taaaattgag cactccgaat gtccttagca gagacggata
     4921 tggatggact gaatttatat cttttaaagc atgcaattgt ctaaaagatg ttcaaaactt
     4981 ttatcagcgt acaggagctc aaatcggttt gttatatgca ttgaaagccg ttgattttca
     5041 ttcggaaaat ctcattgcca acgggagcta tccagttctc attgatttgg aatccttatt
     5101 tcatcctgca taccagaaaa aaaaggatgg gatggacgct tatgaaaaag ctgaaacgca
     5161 gcttcataaa tctgtcagag cattaggact gcttcctttt ttctttgcgg gcaaagccga
     5221 catcagcgga ataggccgga aagggaaagc aaagtcgatc attaaagttc ctcagcttat
     5281 caatttaaag acagcagaaa tgtcggtcaa acgagactat gtcgaaattg atacagctaa
     5341 taatcaccct atgcttgaga ataaatttgt atatgcaaaa gattatgtcg aagaactgaa
     5401 gcaaggtttt tcaaaagcat atatgactat attaaaacac gcttcggagc tgattcgcat
     5461 aatagaaaag agcgaaaaca agatatatgt tcggtttata tcaaaaccga caataaagta
     5521 ttctgcttat tagaattaag ttttcatcct agatttttac acaactctat tgatagagaa
     5581 attttcttat caaaaatatg ggagagacca aagcaagaag atgaatatca atctattgtt
     5641 aaatatgagt tcaacgattt aattaataat gatatacctt atttcaaagt gaaattgaat
     5701 gagaaagact tactaagctc aaaaaataag aaaattgaaa attactttcc ggaaacacca
     5761 gctcaaagtg taaaagaacg aatttcaaat ttatcaaaag acgatttaaa gtttcagctc
     5821 tatgttatcg aactgtccat gcttgcttcg gaggatgatc ggcaaattgt tttgaaagaa
     5881 tttataacaa aagaaccagg acaatatgaa aatgttttca gtagttacca agaaagtatc
     5941 ttaatagaaa aagcagagga attggccgct tatatttata atcaatctta caaagcacac
     6001 acagataaag gaagttcgta ttcttggctt aacgctactc ctattggagt tgatgaaatt
     6061 caatggaact tatccgttat gggtgatacc ttttacgacg ggctttccgg gatggctttc
     6121 acctacctgg ctttatggcg cgtcacgaaa aaagaaaagt atctggacat tgctgaaaaa
     6181 attatgaaag atgtcgtctc tcgttttatt gatattgagg tgaaaccgga cgaagacagc
     6241 agtatgtctg taggtgcttt ttccggagtg tcttcaatag tatatacttt aatgaatttc
     6301 tatatgtata ctaaacgcga aaaatataaa caggatgcaa aacaaatcgc tcagcttatt
     6361 ccgtctttgc ttccttatga taaagaattg gatataatcg ggggcacagc gggggctctt
     6421 attgtaatga tacgttcgtt tgaaatagag aatgatacat tctttttatc attggctgaa
     6481 caatgcggtt catttttaat gaaacaagcg atctttcttg atgaggattt tgtcacttgg
     6541 gaaggtattg caaataagcc gttaacgggt ttttcccatg gaaacgctgg aatgatatat
     6601 gcccttcaat tactcgagaa acattcaaaa catcaagata taagtatgta catccgaaaa
     6661 ggacttgctt ttgaaaattc aaaaaaagta aacggtaact ggcttgatct gagaaaaacg
     6721 gtaaatgaag ctgcaacatc tgcatggtgc catggatccc ctggaattct attaagcaga
     6781 ttagaattga aagattcaaa acaccctgat attgccgaag tggccaaaaa agatctgaat
     6841 aaaaccgttt ctaacatttt ttatgacggt tttggccgag agcaaagcct ttgtcacgga
     6901 gacatgggaa atgctttaat actgatcgaa tatggaaaaa agactggtga aagtcaattt
     6961 gtaaatatcg gaaaaaactt gattttggag agtgtacaag acaaaaatat aggtttctac
     7021 caatgcggag tgggaaggga tgttgaaaca cctaatttaa tgcttggttt ggcagggatc
     7081 gtatatggaa tgctgtatgc agcagacgcg gaattgccga atattctcaa ccttgaaata
     7141 ggacgtgtag atacattagg agacatttat gaaaattaga aaaagaaagc ttccggttat
     7201 tcttcaaaga aatcaatttg attgcggtat tacttgttta gccatggttt tgagcagggc
     7261 tgagggaata aaaatcaatc ctaacaaatt aaaattaaat aaagaaatta tcggaagaga
     7321 cggcactgat ttaattgaaa tgaaaaggat ttctgaaaca ttcgattatg atttcaaagc
     7381 attccgcaca gacaatataa cgcagcttaa agagttaaat aaaaaccatc cgctaattgt
     7441 tcattggaat cataatcatt ttgtagttgt ggacgcattt ggcacagata acgttaaaat
     7501 tatagaccct tcatctggca gactgacaat cacattagaa gagttcaaaa ccttctataa
     7561 tggcatttct attatgttaa tcagaaagaa cgaaattgag agaaaggata agactgcttc
     7621 gtcattaaaa gatgtgtctt catttagaaa gatcggaaaa tatcttttga aagataaaaa
     7681 attattgggg gttattataa gtttcacttt tatttttcaa gcattaaact taatgacccc
     7741 ttttttgact caatatatta ttgattcatt tattgacggg aatgagaaaa ttcttcccat
     7801 accaatgctt ttcatgattg ttattgtttc aatcgcatta ttctttagtc tgtccttact
     7861 cagaatgaaa tttattatca aactgcaatt aaaaattaat aagagtatga ctgataaaat
     7921 aattcataaa atatttagtc ttccattaaa gttttttgag gcgaatactg ccggggatat
     7981 ctcaactaga atccataaca ttgctgtaat tcgtgaagtc atttccaggt tagcgtctac
     8041 tttgatatta gatatcagtc ttatatttgt atttttcata gtcatgtttg tttattcccc
     8101 gatattatct tttatagttt tattgggagc agctatacag gtgatgagta ctaaaatttt
     8161 gcttccgaaa attgaaatgt tcacaaaaca ggaagtaaat agtcaatcca attttcagag
     8221 ccagctaatc gaaatcttaa gatcaatgac atttataaaa acaataggag aaaccaggaa
     8281 tattgagagc caattaaatt ataactttaa tcatcagtta gattatttct ctaaaagaat
     8341 gaattattca tctttactgg gtgcggtctc caatgcaatc aatctatctt tgccattatt
     8401 tattttaatt gtgggtactt ggtcagcagt atctataggc cttacgctag gcgcagtaat
     8461 tgctttttct aacattgccg gacggtttat gtcaccgctt ggatcaatta tcggcagtct
     8521 tgagtctatt aaattagtcg aagaaatggt agaccgcgtt gaagctgtac tggacgaaaa
     8581 agatgaggaa gtaaatgata aaagcagtga actatttaac ccggccgctc ataatatcag
     8641 cttgaaaaat attgatttca gctacaatgg aaacgattat attttgaata atataaattt
     8701 tatgatccgg ccgagagaaa aaatcacatt aattggaaaa actggaagcg ggaaatctac
     8761 tttgattaaa atcattgccg gcctttatca aaaaacagca ggagaaattt gctacggtga
     8821 attcaaaata gaggacgtta atatggttaa gctgagagaa acgttaggtt atattgttca
     8881 agatgtcaat ctgtttaatg acactattat aaataatata aaatatttca atgaaaaaat
     8941 aacaatggaa gaagttgtac aagctgcaaa agaagcatgt attcatgagg atattataaa
     9001 aatgcccatg gggtatcata ccatgattgg agaaaatggt attaccttat caggtggaca
     9061 gcggcagaga atctcaatag ccagagtatt agcgaaaaat ccgcaaattc tatttataga
     9121 tgaaggaaca agcaatttgg ataaggatac agaattaaat atattaaata acatttacaa
     9181 aaaggatatc actgtaattt ctattactca tagaaccgaa tggctcgaat tctccgaatc
     9241 tgtctacgag attgaaaatg gaaacttaaa gaccattaag gccaaatatg aatcgcaact
     9301 gcagcagact tattaacttg aaaggaggtg aaatatggaa tatgaaaaag aacttcagcg
     9361 cgttgtatga aacatcagaa caagaattaa aagagcttgt tggagggcaa aactcagtat
     9421 caataacaac atatccaatc acaaatcata tttgtccaac tatcacagta ggctgcgcat
     9481 gtccgcaaag gcaagtataa aaaacaatcg gggggatttt taatgaaaaa agaattttta
     9541 gcattggaac taatgactga ggaagaatta aaagaattgg cggggggatc ggaggcaact
     9601 ccaatgactg taacaccgac aaccatcaca ataccaatct ctttagcagg ctgtccgacg
     9661 actaaatgtg cgtctattgt cagtccatgt aacgactgaa atttataaaa aactcaaaca
     9721 ataggaggaa ttaacatgaa aaaagatttt caagcactga ctccaatgac tgaagaagaa
     9781 ttaaaaaacc ttgcaggggg atcagatgca accccgatga ccgtaacgcc gacaaccatc
     9841 acaataccaa tctctttagc aggctgtccg acgacaaagt gtgcgtccat tgtcagtcca
     9901 tgtaacgatt aatcataacc ggaaaagaat atgtatatgc gtacatattc tttttctttt
     9961 ttgtcgaaga cagtcaagaa tatataagga agtgataaat gtgaacaaaa cacagaattc
    10021 ggataactat gtttatgaaa actctatgtt aaatgttttt aaagaagagg attatttcga
    10081 aggttttgcg caatattata taagtatttt taaagctcag attgttaaag aaatagatag
    10141 aataccatcc gaaagtttac tggataaggg atgtctagtt gaatcgatat taattaatta
    10201 taagaaaaaa atatactatt tggcggggaa aacacttatc catgagtttc atcaaacttt
    10261 tgacgagttt gatcaaaaaa atgaatctaa aaattatgat atattctcag aaaggctgaa
    10321 aaactccgca tttgttgaag aaatactcaa taattatcct gtattgcaag gtttaatctc
    10381 cagatccacc tctgatttta tacgcttcac tatatctatt attaaacatt gggttaatga
    10441 ctataaaaaa atccaacaaa aattcaatct ttcgttcgga aaaatgagaa agattaatat
    10501 gaatgcagga gatgttcata atgggggtaa aagtgttgtt attattgaat ttgaaaataa
    10561 caaactcgtt tataaacccc gttcacttga aattgatgtt ttttatgaaa aggtcattga
    10621 ttatgtcaat cagtattatc aaactaattt aaaaacacct ttatccttgg atcaaggtga
    10681 gtacgggtgg caagagtatg tacagtctga accgtgcgat aatattgaac aggtaagaaa
    10741 ttattattac caatttggaa tgcatttagg atttatttat gcttttcaag ggtcagattt
    10801 tcattttgaa aatatcatag catgtcgtga taaaccggtg ttggttgatc ttgagactct
    10861 gtttcaaagc agcctctttt tttctgagga gaacaaggaa aatgttaatt taatggcatc
    10921 agcacaggta aataaaacaa tattaaaatc tgcacttttt aactatatga gttttccgga
    10981 agataacggg ctgactaata taggaggctt gataaacaca gaaaatcaaa aaggtgaaaa
    11041 agaagaagta cttcatataa aaacagataa aatttctatg agaaagaaac aatatctctt
    11101 caaaagagga aggaatcttc ctgtttacaa aaataaagta gcagaatgct ttgaatttga
    11161 aagagaattt attgaaggtt tcaaaagaat atactttatt ttgaaagaag atttatatat
    11221 acggaacctt ataagggatt taaattatgc ccctattaga attattgtca gacctacata
    11281 tgtttatgct tcatttcttg aaaccctcct ccatcctatg tatttaaaag attatggaga
    11341 aaggataagg gttttatctt ttattaagga tgcttataca aaatatgaag tatttgattc
    11401 catcagtcca tttgagatca aggatatgat gatcggtgat ataccctatt ttaatgctcc
    11461 tattagtgaa aaaagggttt attcaaattc aatacatgtg gtggatacag ggattatgaa
    11521 acaaagcgct aaacaagaag ttttaactcg tttagcgaat atgtcggaag aagacatgca
    11581 tcagcaagtg agcttgataa atatggcctt aagctccaca gcggctaatt tggatattat
    11641 ttataaaaat caaattgatg attttgtacc tggatatttt aaaaatgaca tacaaatcaa
    11701 agagctgatt caaatagaaa cagattgtat attaaaacaa gcaatcgaat cggagaaata
    11761 tcttcaatgg gtatcaatag tctcggctcc caatggcacc ttatccgtag gaccgctgag
    11821 ttttgggctg tacgatgggt tagctggagt ggggctttat ttttcagctt atgattttat
    11881 ttataatgat gaaaaagtca aatcggttct tcgtaaaata gtgaattcaa ttaatcaaat
    11941 atatgagcac agtatttata aaacaaattt ctctgctttt tacgggtcaa gttcttatat
    12001 ctattttgtc aataaaatga gagataccgg actttattcg gaaaatgaag tgaatagtat
    12061 gtgtaaagca tacttagaga aacttcgtca ggaaaccggt caaataacac atactgattt
    12121 tataggcgga ctcgcaggta tattaaaggt tgtgattcag cttggcaggt atcatcggac
    12181 tgaattaatg gaagatacgg caagggcagt ttgtaaagaa atatgcaaaa gagcgattca
    12241 aaatagaaat gaagcatatt ggaaatccga cgcggatgag aatattgttt tagcagggtt
    12301 ttctcacggt attactggga tttgttatgc actatctgaa tattatgcgc atattgaggc
    12361 atctggagaa gtacttagac tgattgaatc agctctcaaa tacgaagata aattttttga
    12421 tattaaaata aataaatgga gagataacag aaaaaatgag ttggattatt cttccgcaat
    12481 gtggtgtcat gggtcttgcg gtattcttct tggaagaagc aggatatacg agaatgtaga
    12541 cgggcgtatt cacgttgggt atattaatga gtctttagat gacacattgc tgaatggaaa
    12601 tttccaccgt cagggctact cattatgcca tggaacgatg gggaatatag atgtacttca
    12661 cgctattaag gaattatctc tctttaaaaa tcgcaagcaa gagattgaga atacaattaa
    12721 tatatgggtt aaccatttta aagagactct gttaaaaaat ggatggcaaa atggaataag
    12781 aaatgatcat tcgggacttg gtatgatgtt agggaaaacc ggacaattat atgcactctt
    12841 aaggctagtt aataaagaaa ttcccacccc attggctttg gattgagggg ggatttccta
    12901 tataaaaaag cgatcctgta aaggacgctt ttttatatta attttattcc gctgattaaa
    12961 ataatcgccg ccatcacaaa ctgcagcggg cgcggtgaga atttcggcga aaagaagctg
    13021 ccgagaagca cacccggcac agagccgatc aacagattca atacaagcag gtaatcgacg
    13081 cttccgaagc ttgcgtttaa cagaccggca gcagttacga gcagaaaggc atgtgcgata
    13141 tccgttccca ccacttctgc cgttttcatt ctgaacaggt ataacatggc gatcgcaaat
    13201 aatgagccgg acccaataga tgtcaggccg acgatgaagc cgaaaatgac gccgatcagt
    13261 atcatgagtg tccgcttttc ttcaagcgtt ttttgctgcc agcggttcgg ccgcagtttt
    13321 ttatcgaaaa aaaggcgggc gataatggaa atagcgacaa gggtcagcac gtagccgagc
    13381 gcctgtttga taatctgctc ctgatgctgg tgaaaagcgg gaaacaagtg aagaataccg
    13441 atggcggctg ttgcgctggg aatgctcccg agcgccaagt agccgacaag tttaaattga
    13501 acggtgcgct gcttccaatg agaaacaaca ccgaacagtt tggtgatgga attatataaa
    13561 aggtcagtgc cgacggcgat tgaggggttg atccctaaaa cgatcagtaa aggagtcaaa
    13621 agcgccgctc ctcccacacc cgtcaatccg accagcgttc cgacaaagaa acccataaac
    13681 acaatgctta cagtcatctg tgtgcctcct gaataatcct actattttta tcagattata
    13741 tatgattaag aggcggtaat caattaaatt ttcggaaaat tttatacaga acaaaaaaat
    13801 ccgcctgcct gctgttattt cgcagatcgg cggatgatgg ccggattatg atttttgctg
    13861 ataaaacgga agttccgtgt ggcccatttc tctgacatac acgaaaagat tgcctttatg
    13921 atgaatttca tgctccatgg caagctgaag gagagccgcg ccggttattt ttctgccgaa
    13981 agaggcagtc aggtcaattt cgcggttcag ctgctcttca gtcagctgtg acaggatgtt
    14041 tgtcgttttt tcagtacatg cttcagccag tttgacgagg tctgtttccg cttcttcttt
    14101 cggtttgttc tggatagctg atccgtttcc gtcgttaatg acgtttgcaa acataagaaa
    14161 agaataaacg atgtgtttta caagttcctg agcggacatt gatgtctctg ccggcttgta
    14221 gtcgtaatgc tcgcggctga ttttttccgc cagctcaatc gtcacgtttc gatgtgacag
    14281 aaagtggctg accaattgat tttgtgctgt catgtgaaaa cccccattta atacagaata
    14341 aaagctgcaa ggatatgcta tatcaacggc acggaagaaa caagcaataa gcctgtgatg
    14401 gagataaatc gttgcggata tccgaaattc gacaattgcg gtctttttgc gttcttcttt
    14461 ttctagcaat tatgataaaa tatgacatat ctcggtcatt ccaaaagggg ggatttattg
    14521 aggatgaagc aaactattcc gtcctctttt gtcgggctca aaattaatga atggtatacc
    14581 catatccggc agtttcacgt ccttgaggcg gagcgcgtca aacgtgaagt agagagagag
    14641 attgaggata tggaagaaga tcaggatctg ctgctgtatt attcattaat ggaattcaga
    14701 caccgcgtca tgctggatta catcaagccc ttaaaggagg acccttctca gcctgagttt
    14761 tcagaattat tggaagacat tgaaggcaac cagtataaac tgacaggact gcttgattac
    14821 tactttaatt tttttcgagg aatgtacgaa tttaaacaga aaatgttcct aaacgccatg
    14881 atgtattaca aacgggctga aaaaaacctt gcactcgttt ctgatgacat cgagaaagct
    14941 gagtttgctt ttaaaatggc cgagattttt tacaacctga aacaaaccta cgtctccatg
    15001 agttatgccg ttcaagccct tgaaacgtac caatcgtatg agacgtacaa cgtccgcaga
    15061 atccaatgtg aattcgttat tgcagggaat tatgatgaca tgcagtatcc agaaagagca
    15121 ttgccccact tagaacttgc tttagatctt gcaaaacaag aaggcaatcc ccgtcttatc
    15181 agttcagcct tatataatct cggaaactgt tacgaaaaaa tgggagacct ctctaaagca
    15241 gccgaatatt ttgagacatc cgtttccatt tgcaggtcag aaaagttcga taatcttccg
    15301 cattctattt actcattaac acaggttctt tataaacaga acactacagc cgaagcagag
    15361 aagcaatatc gcctcgggct cagtatcgcc cgcgaataca atgatgaatt gtttgtaaat
    15421 ctgttccaat ttttgcatgc gttatacggc aaggaaatgg ataacgcatc cgtcaggcac
    15481 acgtttgatt ttctggaaga acacatgctg tatccgtatg tggaagaatt ggcgcatgat
    15541 gctgccaaat tttacatgaa acacggacag cctgaaaaag cgctcacgtt ttatgaaaaa
    15601 atggtgcacg cccaaaaaca aatccagaga ggagattgtc tatatgaaat ctaaactgtt
    15661 gtcaggattg ctgcttgttg ctgtcgggtt cagctttaca caggtgatcg gccatgaaag
    15721 ccatttggaa aaccaagcgg acggcacatt ccatattgcc gcgcgcaacc aaacataaca
    15781 taaagaccct tctttggaag ggtcttattt tttgcatgcg tatccattcc atttttatcc
    15841 gaatgcaggg tctatatgct caagttatct gtcctacgaa tgccacctat tgatgaaaaa
    15901 ggcataagga gagatgaaga gtggggattg aagtgaaaaa acggctcgta tcggctgata
    15961 aatatgcgtt aaaatgtccg aatccgatga cgccggagta tattaccatt cataacacgg
    16021 caaacgacgc atccgccgct aatgaaatca gctatatgac gggaaacagc gaatcaacga
    16081 gctatcattt tgcggttgat gacaaagaag tgatccaggg aattccgttg gaccggaatg
    16141 cctggcattc gggagacggc acgaacggta ccggaaaccg aaagtcgatt gctatagaaa
    16201 tctgttacag caagtcaggc ggcgaacggt acagagccgc agaagaactg gcgattgcgt
    16261 tcgcggcgca gcttttgaaa gaacggggct gggggattga cagaatcaga aagcatcagg
    16321 actggaacgg aaagtactgc ccgcaccgca ttttgtctga aggccgctgg gatgaagtga
    16381 aggcgaagat tgcaaagaaa ttaagcggaa gtatgccggc gaaaaaagcc tctatttctt
    16441 cttccgcctc tgaataccat gtgaaaaaag gcgacacctt atcggaaatc gccgcatcgc
    16501 acggtgtcag cgtaaaatcg ctgcaaagca tcaaccatat caccgatccg aatcacatta
    16561 cagtcggaca agtgatcaag ctcgctcaga cgggttcttc ttcaaaaagt caggctgtgc
    16621 cttcctatcc gcttccatcc ggtgtgatca aagtgacgaa accgctgacg aaagggacaa
    16681 acgtaaaaca agtgcaaaac gctttatccg ctctttattt ttatcccgat aaaggagcaa
    16741 aaaatcatgg gacggacggc gtttacggtc cgaaaacggc aaatgccgta aaacgttttc
    16801 aatccgtcag cggattaacg gcagacggaa tttacggccc gaaaacgaag gcgaaaattg
    16861 aagaaaaact gtaatcaata aaacggaagc tccccgggct tccgtttctt cttacataca
    16921 aactgcggca agggcctttt gaatatcata aatgctttca tcttttttaa actgctttga
    16981 gacagcggga agttccgctc ctgaaatcca aattttcagc tctgaatcaa ggtcaaagcg
    17041 gccggcggtt tctacgctga atctggaaat gctcttgtac ggaatggatt gaatctccgt
    17101 tttcttcccc gtgagtccct gtttatcaac aagaataaga cgcttatccg taaagacaat
    17161 gatatctcgt acgagcttaa acgcggcgtt gacattctca ccttccagca gaatacgggc
    17221 cagttcttct tttgcttcag ccgtcgatat tgtcgacgca ttgcccagca atccattgat
    17281 gaaccccatg atatatcccc cctgatacgt attctatcaa atcatactat aaaaaggttt
    17341 ccattcccag atgagtagag taaactggtg ctgactggaa aaggagagca tgttacacat
    17401 gaaagataga tatgacaatt tcgcagccct ttcagctgct gaatcggaat acagaattat
    17461 ttatgaagaa aaagagggaa gtaaatgtat cgtcctcgct ccccacggcg ggagaattga
    17521 gccgggtgtc agtgagctgg tgcgggcatt ttctgaccaa agctcaattt acttatttga
    17581 agggacgaag cggtgcaata accgttctct ccacttgaca agcacacgct ttgacgaacc
    17641 cctggcttta gaaaaagtga ccgcccatca ttacggattg gcttttcacg ggtatcatga
    17701 tctgaaaaag gcaaatacac tcgtcggggg cgcggatttg gaaaaagcaa gactgatttg
    17761 tgatctgctg cgtgaagcgg gatttgatgc cgagctgaca gagaagaatg atcggctggc
    17821 aggtgtaaat cccggcaaca ttgtcaatcg gacaaaaagg aaaatggggc tgcaattgga
    17881 agtgagcacg gcgcagagac acgcgctgtt cagcaatttt ggctgccggg gagaaaaata
    17941 tacgccaacc gatctgtttt ttcgttatgt agaagccgtg aaggccggtt tttatgataa
    18001 atgaacaggg gggcccgttt ttacattcac tggagctatg cggcgcaaga agtgcttggc
    18061 gggcagcacg gtgagaacag cgtcatgatg caaaaacctt tcctgcgatt taaaatgatg
    18121 acattctgcc ggctgcgttt taagccggcg gagaatcgct aattttcaat aaaatacggc
    18181 gttttttctt cagcggcatg caagtgtgtc tgtccgcttc cataatacac attcggccgc
    18241 ttgtcggata acagacaagc gagccgcttc tgaaattgaa tacctgcttt acgccgttca
    18301 aacagctcga gccttttttc cgcaaatgat gccgtcaccc ggaaagcggc tgcgattaaa
    18361 ataacggcgt ggctcctccg ctggggaagc tccatgttta acagcataaa ggtcggcaca
    18421 cagaagtggt acataaaatg gttggcctga aattcctgca gttccctgaa cagcttgttc
    18481 atatgaaaat ggttcccggt atgcttcagc acatggcaca gttcgtgcgc aaaatcctgc
    18541 cattgctctt cgggtgactt tttttgattc aggacgatgc tgtacatgcc gtcccgcttc
    18601 agcatcatac tgtgcgtatc ttcaaaatga atccaaatgt caagctcctt ggcaatcatc
    18661 tgcatatcaa tatggagagg ggcggtcatt cccatgcggc aatataagtt tttgacgtat
    18721 tcctcaagat gtgttaaaaa atcgcccaat tgaatacacc ctttcgaacg tatgttcttt
    18781 tttaagcgag aaagaaaagc cctgatcgga ctttgaatca attccctttt cttttaaaaa
    18841 taaacattca gcttttatat cggctgaacg ttaagcagtt taaaggaaaa gagcggatta
    18901 tttatgtttt ggcctgcggt ttttctcttt ttcttttaaa taattaatga attcaatggc
    18961 ctgctgtttg ctttccggcg aaaagtcctg catgtcccga tacgcgatct gcaggtcggg
    19021 atcagcaaac agatcttcat ctgaaggttc ttttccggtt aacaaataat ccgttgacac
    19081 attgaaataa tccgcaagct tttgcagcgt ttcataatcg ggttcagatc ggccgttttc
    19141 ataatgagaa tatctggcgc gcgagacacc gatatgattt gcgacttctt cctgcgtttt
    19201 ctttcctctg agactcttta atcttccgcc tatcatccga atgacctctc ttttttcaac
    19261 accctaagtt acttatgatt atagatacaa aatgtatcaa aataaagaga tgataaaaaa
    19321 agtatcaaaa aggtcttgat gatacgaaat gtatcgtata taatcaacat cataaggata
    19381 cgaaacgtat caaaatacga taagaaattg atcaggaggg tgagagatgc agccgataat
    19441 catccgtttc agcagcaatc cggctgacca gagatgttta gggaaagcag gcggttcgat
    19501 atcttttacc gcttgcggac ttccggtatt ccgatttgat aaccgattgc agtatgaacg
    19561 ctatataagt ctgaagaaaa acggagacgt ccaatatgaa tcgtaaaagt tacccgtttt
    19621 tcatctattc cggattattg aattcagaac attatgaaaa aatagggtcc gccatatggc
    19681 tgtttttatg gttcatcagc tcaacgacaa aggaacacgt aaaagacggc gtaaagtggg
    19741 ggatcgtcct cggtcataaa cccgtaaaag caaaagaaat ggccgacgta tttgccgtca
    19801 gcgaaaaaac cgtcagacgg tggcttgagg ttttggaaca gcatgaatat atcaaaaccg
    19861 tccgcgcccc ttacggactc atcgtctcca taaagcactc gaaaagattc acgccgaaaa
    19921 agacattgac ccgcccggaa gtcacagacc ggacaatatc ggcggatcac cgggacaaaa
    19981 atgtccggag agaaatagat ataacaaaaa atcatactgc tgaagaagcg attaacgaca
    20041 ttgccgccca ttttatcaga ttaaggtctg cacaggaggg gcggagcgta tacccctcgc
    20101 cccgggatta tcaggccatc gcccgtattg tttccctcgg tgcgtcagca caagaagcaa
    20161 tcaaatggct cggcgaatgc tttaccgctt ttgaacagcg gcgcacctct tcagctgaaa
    20221 cgatcaaggc tttcagctat tgcgccaagt atatggaaga ccgcttgaat gcacgaattg
    20281 cgggaaggac aatcacaaca aaaaaagaga ggaatacgat acatgacaaa acgaacgatc
    20341 gagcagatac tggccgacct gaaaaacgga aaacgtccat tactggcgga cagaccggaa
    20401 gaatcagacg aaagccgctt tgactgtccg ctctgtaaag atcagggcgg ttatctcaaa
    20461 aaccagctgg gaatggatgt gtgggttaag tgccgctgcg ccgccgaacg aaaagcagag
    20521 cgcatcctca gcgcaagtga gattacagat gcctttcgga agctggattt caaaggattt
    20581 atcacgcggg gcaagcctca ggcagtcgtc gacgcatatg agtgcgccct tgaatatgtt
    20641 gaaaacttcg acaagatgaa aaactgccgg aaaaacagca ttgccctttt agggcgtccg
    20701 ggatcgggaa aaacccatct tttgaccgct ctcagcaatt atgtcatgag acagaagcag
    20761 acaccggtgc tgtattttcc ttttgtggag ggctttacgg atttaaaaaa tgattttgat
    20821 ctgctcgatg caaagcttgg ccgtatgaaa caggcggatg tgctttttat tgacgatctg
    20881 ttcaaaccgc tgaacggaaa accccgggcg accgattggc agattgaaca aatgtacgcc
    20941 gtcgtgaatt accgctattt aaatcataag ccggttctta tctcgagcga gctggcatgt
    21001 gacggattgg tgcaggttga tgaagccttg ggcacaagaa tttatgagat gtgcagcgat
    21061 tatttagtca tcattaatgg caattcattt gacgtaaacc acagattaga gggggcgaga
    21121 taatgtgtaa gctgtgcggg ccgaagaagg tcattgtgac ggaaacgggt ttcggcgctg
    21181 tctttcaccc ttgcccgaac tgcaaaacag gcactgattt aacgccggtc attaaacggc
    21241 ttgaacgaat ggttcaagac gcaaaagcga ggcttgatgc acgtgtgtaa atatatcaaa
    21301 tggctttttt gcctgctgtt cagggcaaaa cggatagaaa agcaaattga agcatggcat
    21361 gaggctgatg gaaagtgagg atcaccattg caagaaaaac acagccccgc tccatggcgg
    21421 gccgtacaca gcggagaaga aaaacccatt tacatttatt ccgcttacag cgaagcggat
    21481 aaagagaagt tcccttattc aaacggaagg ctcatcgcgg ccgttttcaa cttaagttca
    21541 tactcacagc agatcaacgc ggcattgatg gcgaaagccc cggaactctt tgaggcggcc
    21601 gagacggctc tccgcctgct ccggggagaa agttctgaag aaaaagaagc gttcataaat
    21661 aagctcggaa gcctcataca tgaagtaaac atcttgaaaa agacggagga cgtaaaacat
    21721 gaatcctaaa aaactgactg acattgaaca tacaacatta aaaagccagc tggaagaagg
    21781 caaggttcgg gtcatcattg tagacggact gaagaaggaa gcatggctcg ccgaagcgcc
    21841 ggagcacggc aaaacgcttg tcgaaacgcg aaaaggggat ctggcccggg tcgaatatga
    21901 aatcggcttt aaattgaatt aaaaacagaa tacgtccaag acggaaagcc tgcggacact
    21961 gatcaatcgc gcacatgctg cgcattggtt ggtgtccttt tttgttccga aaaagaggag
    22021 gatctacatg gaagacttac tatttgaata taaacgcacg ctgaaagaga cgaaaaagtg
    22081 gtacaagcag ctggaggaag ccgatgaaac ggtgcttact tcagaagaac tgaaagataa
    22141 aaaaatcatc agaacgatca ttacagatgt ggaatatgtc atcgaatggc ttgaaaaagg
    22201 ccggcagccc ggcataagaa gagcgataga ccgcagagac gcttatcaga gaatgctgat
    22261 taaagatccg agaattatag aaacctattc acaggcgctg atgtttgaac cgtccgcaaa
    22321 tgtgactgaa gaagacagaa tcagactgcg ggacgcatta gccgttttaa cggatagaga
    22381 aaaagaaatg ctgctgctcc acaaagcgga atgcttttcg tatgaacgga tcgccgcctt
    22441 gctgaatgta aagaaatcaa ccgtacaaac gacggtcaaa cgggcgcttc tgaaaattca
    22501 aaaacagcag gaacaaagaa atcaatcgcc tgcttcataa gttgtcatac gtttgccacc
    22561 tagaagtgaa cagacgatca caaaaagcgg cccgattaga agccgctttt tattatagac
    22621 aatcatgtcg gaggtggcgg tgatgccgta gcatgaaaaa cgcaaaaaga gaacaggcat
    22681 ttacaatcta tcagtctcat aaaggccgca tcacaaatcg cgcccttgcc ggcaaatcag
    22741 gcgtatccgc aagaacgatc ggcagatgga aaaaagaagg gcgctgggac gaggcgctcc
    22801 ataagaacgc ggaaagcggc ggaaaaaaca ccccgggcga aggtgatgag ttaaacgaac
    22861 gccagcggct gttttgtctt tattat
//
