LOCUS       NZ_CP058693            22268 bp    DNA     linear   CON 08-SEP-2024
DEFINITION  Streptomyces sp. Rer75 chromosome.
ACCESSION   NZ_CP058693
VERSION     NZ_CP058693.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. Rer75
  ORGANISM  Streptomyces sp. Rer75
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10474412)
  AUTHORS   He,H.
  TITLE     Genome analysis of Streptomyces sp. Rer75
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10474412)
  AUTHORS   He,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-JUL-2020) College of Pharmacy, Henan University of
            Chinese Medicine, Jinshui East Road No. 156, Zhengzhou, Henan
            450046, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. Canu V1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 76.63x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013414305.1-RS_2024_09_08
            Annotation Date                   :: 09/08/2024 05:25:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,857
            CDSs (total)                      :: 8,765
            Genes (coding)                    :: 8,460
            CDSs (with protein)               :: 8,460
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 5 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 305
            CDSs (without protein)            :: 305
            Pseudo Genes (ambiguous residues) :: 0 of 305
            Pseudo Genes (frameshifted)       :: 145 of 305
            Pseudo Genes (incomplete)         :: 204 of 305
            Pseudo Genes (internal stop)      :: 20 of 305
            Pseudo Genes (multiple problems)  :: 62 of 305
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:27:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4949778
            Orig. end                         :: 4972046
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP058693.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22268
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="20"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22268
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22268
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12268](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12268)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(198..211)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            315..1217
                     /gene="nac"
                     /locus_tag="HYQ63_RS20875"
                     /old_locus_tag="HYQ63_20875"
     CDS             315..1217
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nac"
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009716672.1"
                     /locus_tag="HYQ63_RS20875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20875"
                     /product="nitrogen assimilation transcriptional regulator
                     NAC"
                     /protein_id="WP_179935325.1"
                     /transl_table=11
                     /translation="MDTRRLYSFVKIVDAGSITRAADILHIAQPALSQQLSMLESHFKQ
                     QLLIRSKRGVAPTEAGRALYRHAQLILRQVELAQAAVDVSGRAPAGSVSVGLAPYSMGA
                     ALALPLLTSVRERYPDIVLHINENFGGVISEAIMTGRMDMAFIYGAGPLRGVQFEPLRT
                     EDLFLIAAPGRTTEPGGGADVPLEELADVELLLPSRIHTIRQVVDAAFQQASLQPRVIG
                     EIESVLTLVSAVGADLGATVLPWSAARAILDVQNLVVRRIVNPTIPVKLSLCTSDHQPL
                     SEPAHAVHDLFHELIADFG"
     gene            complement(1251..2375)
                     /locus_tag="HYQ63_RS20880"
                     /old_locus_tag="HYQ63_20880"
     CDS             complement(1251..2375)
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009716670.1"
                     /locus_tag="HYQ63_RS20880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20880"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_179935326.1"
                     /transl_table=11
                     /translation="MIQARTHLDQPYPPAPFAAGVPVLILGAVAAIAFVTGDGTSWLPL
                     LAVGPALAAAACRPWAVLRIGFLAVALGAALGAWQAAPVHGQAVVLSTLIAVTLASCLA
                     SVLRGRRERVLAAVRSVAEAAQNALLRPVPARVGQFQVAVRYSAAAAEARVGGDLYALV
                     STPYGVRLIVGDVRGKGLPAVSTAALVLGVFREAAYDEPDLLDVVGRIERSLARNLAPD
                     DFVTAVVAGCPADGRMEIVNCGHAPPLLIGPAGAVVPVEPLRPAPPLGLASLGGEAPSL
                     EVVPFADGDQMLLYTDGVIEARDHGRAYFPLAERVPGHVSDEPSRTLAGLHDELLAHVG
                     GRLHDDAALLLLRKPASGRVASSAVDAAADTTGV"
     misc_feature    2340..2355
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.3"
                     /tool="antismash"
     misc_feature    2479..2493
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.63"
                     /tool="antismash"
     gene            complement(2484..3278)
                     /locus_tag="HYQ63_RS20885"
                     /old_locus_tag="HYQ63_20885"
     CDS             complement(2484..3278)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313583.1"
                     /locus_tag="HYQ63_RS20885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20885"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_179935327.1"
                     /transl_table=11
                     /translation="MGTPGGPTLITSVQRAFRLMEAVGAHEGGAPAKQLAREVGLPLAT
                     TYHLLRTLVHDGYVHRLPDGGFVVGDKLHTLQVGSRGQALLNRVRPALAGLRDELSAAA
                     YLTFYEDGEIRVAEIVDSPRAPRVDLWVGFEDAGHATALGKCVLRELGDEARSDYLSRH
                     PLADLTPRTVTRPAELLRRLDASAADQPVTDLEEYALGTVCFAVPVYSGDRLGSLGVSL
                     QAGRAGLAGQAGRADRAARLEEIRERLLPTADRVTRSLSLTI"
     gene            complement(3396..3854)
                     /locus_tag="HYQ63_RS20890"
                     /old_locus_tag="HYQ63_20890"
     CDS             complement(3396..3854)
                     /NRPS_PKS="Domain: Polyketide_cyc (9-108). E-value:
                     1.1e-16. Score: 53.3. Matches aSDomain:
                     nrpspksdomains_HYQ63_RS20890_Polyketide_cyc.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009716668.1"
                     /locus_tag="HYQ63_RS20890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20890"
                     /product="SRPBCC family protein"
                     /protein_id="WP_123099092.1"
                     /transl_table=11
                     /translation="MSTVRETVEVEVPLHTAYNQWTQFTEFPRFMEGVDQVTQVDDRHN
                     HWSTSIAGVHREFDTEIVDQLPDERIAWRTTSGDVQQQGLVTFRSLDATHTEVNLAMVF
                     EPTGMAEKAADMTGTLDRRIKGDLHRFKDFIEHRGQEEGGWRGRISPG"
     aSDomain        complement(3531..3827)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HYQ63_RS20890_Polyketide_cyc.1"
                     /domain_subtypes="Polyketide_cyc"
                     /evalue="1.10E-16"
                     /label="HYQ63_RS20890_Polyketide_cyc.1"
                     /locus_tag="HYQ63_RS20890"
                     /protein_end="108"
                     /protein_start="9"
                     /score="53.3"
                     /tool="antismash"
                     /translation="VEVPLHTAYNQWTQFTEFPRFMEGVDQVTQVDDRHNHWSTSIAGV
                     HREFDTEIVDQLPDERIAWRTTSGDVQQQGLVTFRSLDATHTEVNLAMVFEPTG"
     gene            complement(3914..5158)
                     /locus_tag="HYQ63_RS20895"
                     /old_locus_tag="HYQ63_20895"
     CDS             complement(3914..5158)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019356673.1"
                     /locus_tag="HYQ63_RS20895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20895"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_179935328.1"
                     /sec_met_domain="DAO (E-value: 2.8e-60, bitscore: 203.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPRSAVVVGAGIVGLATAWALQGRGVEVTVAERRRPAAGASWG
                     NAGWLTPALAMPLPEPAALRYGVRSLVTPTSPVYIPPRADPRLARFLLSFTRHCTPRRW
                     RVLATTFAALNRHALAAYDDLAAGGVEEPTVPVDPMLLAFGTAAERAGMVEELEHARAA
                     GYEIPYEAIDGDRARSLEPVLSDAVGAGIALHGQRRLNPGNFVRALADAVRERGGKVVE
                     RAEVSGIRDLGTGVAVGTSQGDLRADVAVVSTGTWLNRLVRPFGVRVPVQSGRGYSFSV
                     PAAGAPARPTYLAAQKVVCTPLGDGRVRVAGMMELAPPERPVDPRRIQAIIAAARPLLR
                     DVDWDARTDEWVGSRPCTADGLPLVGPTASPRVYVNGGHGMWGVALGPLTGRLLADAIA
                     TGTAPAELAALHPLR"
     gene            complement(5322..6530)
                     /locus_tag="HYQ63_RS20900"
                     /old_locus_tag="HYQ63_20900"
     CDS             complement(5322..6530)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024945.5"
                     /locus_tag="HYQ63_RS20900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20900"
                     /product="CdaR family transcriptional regulator"
                     /protein_id="WP_179935329.1"
                     /transl_table=11
                     /translation="MYDDSPDGLLALANSIAGLVGAPVTIEDDASELITYSPGQEYSDD
                     ARVATILSRRVPDRYRPLLRNDRLDVRLAGSSVPLYADFRASGAPDVLPRAIMPIRVDD
                     LSVGSIWAIVPTAPSREQRAALVEAAALAAPVLARQIARRRGEEARRAAAVRALLAGGA
                     GAVEAAAELPLAPGPLAVVALRPVTPAASGEPLRRALAGLDGLAGFAGFAGPAGAAHGG
                     VHAEADGAGYAVLPVRDEQRLARVVRELQDRSGLVAGVGRTVPGPDALDRSRADADLVV
                     RLLTRLGGSGGAAAHIRDVHLDALLMQTVDLADESGHDPLGAIAELERYDRERGTELLD
                     SLARYLAAGEDARLAARQLHIHPNTLRYRLRRAHEIAGLDLADPAAKFEIQLRLRLRAL
                     RLP"
     misc_feature    6619..6633
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            complement(6641..8080)
                     /locus_tag="HYQ63_RS20905"
                     /old_locus_tag="HYQ63_20905"
     CDS             complement(6641..8080)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009716665.1"
                     /locus_tag="HYQ63_RS20905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20905"
                     /product="amidase"
                     /protein_id="WP_179935330.1"
                     /transl_table=11
                     /translation="MTDHDDELCYKTARELSALLRGRELSAREVVRAHLERIERVNPDV
                     NAIVTLVADRALDAAAAADERIVAAGADGVGVLHGLPIAHKDTHNTAGIRTSHGSPLVD
                     GVPDQDDLIIERIRDAGAITLGKTNVPEFAAGSHTFNPIFGATHNPYALDRSAGGSSGG
                     AAAALASGMVPIADGSDTGGSLRNPASFNNVVGLRPSPGRVPTWPAANAWTTLSVKGPM
                     ARTVADTALLLSAMAGPDPRSPIALEEPGARFARPLDRDLTGLRVAWSPDLGGLVPVEP
                     EVAAVVEASAGVFEDLGCVVERACPDLSEGEEVFRTQRAALFEVAFGPLMDRHPEGLKR
                     TIRENAEAGRRLTGPEVARAEVLHTALFHRVRAFFERYDVLLLPVSQVPPFDIGIEYPT
                     EVAGVAMGDYLEWMRSAYLVTSTGSPALSVPAGFTPAGLPVGLQIVGPHRADFAVLQIG
                     HAFEQATGYGRRRPESTGAIG"
     gene            complement(8143..9636)
                     /locus_tag="HYQ63_RS20910"
                     /old_locus_tag="HYQ63_20910"
     CDS             complement(8143..9636)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020556039.1"
                     /locus_tag="HYQ63_RS20910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20910"
                     /product="sodium:solute symporter"
                     /protein_id="WP_179935331.1"
                     /transl_table=11
                     /translation="MSVVLAVSLLGMCALALCGFLGRTGRSTDLAEWAVGRRNFGTAAM
                     WFLQAGEVFTTFSFLGVAGVAFTGGNAATYAVVYLALAFLLLYFVQPRLWRLGKERGYL
                     TQADYFTDRYRSPLFGKVVAVIGLIFLLPYIQLQLTGLGMVVGLVTGSTASGRLSMVLA
                     SVLTAAFVLWSGIRGLKNSAYFKDVLTVGVMAVLAVVVPLHYVGGGVGEVFRRVHEVQP
                     QMLTVHGGAQDQVWWTTSVLVSAIAGGMMATPHHWPPLMAAGGPRAIRTNNIFMPLYQV
                     ALMIPIMIGLTGVVARVDGDGDGVLLTLAQGALPDWATGLVVVAAAASAMVPAGAMCIG
                     ISTLVAQNLLPPGRESARMRVNHSVVVLAIGLALTLGILRPGLLADLQLLTVSGFIQLV
                     PGLLAVLGRRRLLTARAALAGLAAGEAVVTWLTLAEVDVRHVNAGLVGLGVNVAVALLV
                     QLLFPRPAPSRSAPAPDRASAPRTPAATAARRADEFPRG"
     gene            complement(9633..9869)
                     /locus_tag="HYQ63_RS20915"
                     /old_locus_tag="HYQ63_20915"
     CDS             complement(9633..9869)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009716663.1"
                     /locus_tag="HYQ63_RS20915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20915"
                     /product="hypothetical protein"
                     /protein_id="WP_179935332.1"
                     /transl_table=11
                     /translation="MSRRKLLVLLPVVPALALLASVWLPFVNAERLWFGMPSLYVWVGG
                     WVLTLTPALAAVEWGLFRHGERVAAGAAAGEGQ"
     gene            complement(10001..12268)
                     /locus_tag="HYQ63_RS20920"
                     /old_locus_tag="HYQ63_20920"
     CDS             complement(10001..12268)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009716662.1"
                     /locus_tag="HYQ63_RS20920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20920"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_218929575.1"
                     /sec_met_domain="T1TS (E-value: 4.9e-83, bitscore: 278.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFQLPDFYMPYPARLNPHVEEAREHSTRWARERGMLEGSGIW
                     EQEDLDAHDYALLCAYTHPDCSAAELALITDWYVWVFFFDDHFLERFKRSQDRAGGKAY
                     LDRLPLFMPMDPAAAGMPEPENPVEAGLKDLWVRTVPAMSPDWRARFRESTENLLNESL
                     WELSNINAGRTPNPVEYIEMRRKVGGAPWSAGLVEHAVGAEVPAVIAESRPLRVLRDAF
                     ADAVHLRNDLFSYQREIEEEGERSNGVLVLETFLGCTTQQAADAVNDLLTSRLQQFENT
                     TFTELAPLFAEHGLDAAACAGVMAYVKGLQDWQSGGHEWHMRSSRYMNGGGAAAEPAWS
                     PFSVSGLGIGGLGVGGPGGSGLGVSAADIRLTTGRAERARARGFSHVPHQRVGPSRLPD
                     FFMPFTARLSPHLDRARRNLVEWTHRMGIFGPQPGVPDSDVWDERRLRAADLPLCAAGI
                     HPEASPDELDLTSGWLTWGTYADDYYPQVFGRKRDLTGAEACNERLKTFMPVDAGPTPV
                     PAGGLERGLADLWSRTAGPMEEDARRAFRQAVDDMLDSWLWELANQAQHRIPDPIDYIE
                     MRRHTFGSGLTMSLCRLAYGRRVPPGICDSGPVRSLESAAMDYATLLNDVFSYQKEIEF
                     EGEVHNGVLVVQNFFDCDYPTGVAIVQDLMTSRMRQFQHVAAHEFPVLYEDFGLSAQGR
                     AALEGYVRDLQNWMTGILTWHREVARYREEELRHEAGAPRQLFGPTGLGTSAARLPVGA
                     GR"
     gene            complement(12467..13750)
                     /locus_tag="HYQ63_RS20925"
                     /old_locus_tag="HYQ63_20925"
     CDS             complement(12467..13750)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009716661.1"
                     /locus_tag="HYQ63_RS20925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20925"
                     /product="acyltransferase family protein"
                     /protein_id="WP_179935333.1"
                     /transl_table=11
                     /translation="MNISSLRRAQRAPAPGPVPPPVRPPVPVSVPSSSAAPKQRDAFFD
                     NAKYLAIVLVAMGHSWEPLRDGSRAASALYMFVYAFHMPAFILISGYFSRNFDLRPDRL
                     KRLLTGVAVPYVIFESVYSLLRGWAGGDPSYPISLLDPWYLTWFLIALFVWRVTTPVWR
                     IARHPVPLALAIAALASCSPDIGDDLDLQRVLQFLPFFVAGLHMRPEHFRMVRRREVRM
                     VALPVAAAALVFTYWAVPRMNAGWFYHRDSAQEMGAPWWSGIVMTFALFGCSMVLTACF
                     FAWVPGRTMWFTALGAGTLYGYLLHGLLIKGSHFAGWYDPSWLHTPAGAIAVTVIAAVV
                     VTALCSPLVQRTLRFAMEPRMEWAFRSVAGSPAAGPGAGPAAAGSGAAVAGSGPGATVG
                     GSGPGAVVARSAATPRAVVPAQATRPPG"
     misc_feature    complement(13733..13735)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14093..14338
                     /locus_tag="HYQ63_RS20930"
                     /old_locus_tag="HYQ63_20930"
     CDS             14093..14338
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656740.1"
                     /locus_tag="HYQ63_RS20930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20930"
                     /product="ferredoxin"
                     /protein_id="WP_179935334.1"
                     /transl_table=11
                     /translation="MRLVVDLNRCQGYAQCAFLAPDVFTLHGEEALLYTPHADDTQREN
                     VARAAAACPVQAILVEGPDDDLVDGPVGDEGLSGVR"
     gene            14286..15722
                     /locus_tag="HYQ63_RS20935"
                     /old_locus_tag="HYQ63_20935"
     CDS             14286..15722
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014177797.1"
                     /locus_tag="HYQ63_RS20935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20935"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_179935335.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.4e-41, bitscore:
                     140.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWSTARSATRACPVSADGAPHTLRREGRIVIVGASLAGLRAAET
                     LRDEGFSGSLTIIGDEPHEPYDRPPLSKQVLLGRAPADHTTLPRRREVYARWRLGVAAT
                     GLDMTARRVRLADGDEVGYDRLLITTGVRARPWPHPLEAELDGVFVLRTREDAAALHRR
                     LSAAPRRVLVIGAGFTGSEIASACRERGLPVTVAERGPTPLVGALGGVLGEVAAGLQRA
                     HGVDLRCGVMVTGLEGDAAGRLRRAHLSDGTALDADVAVVSLGITRNTEWLAGSGLGAG
                     PRGIACDAGCRAFDVRGIVTDDIFVAGDVARSPHPLFGYQFLSLEHWGNAVAQAEIAAH
                     NMISASADRRPHLWVPAFWSSQFGVNIKSVGVPSMGEEVLIAQGSLAERRFTAVYGYQG
                     RVIAAVTFDQSKWLAFYQRLIETAAPFPPPFTTVDRRTEGLRPVPADFPDPTLPTHGPT
                     VTLSGYSPSDRRIAFTPSRV"
     gene            15771..17018
                     /locus_tag="HYQ63_RS20940"
                     /old_locus_tag="HYQ63_20940"
     CDS             15771..17018
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009716659.1"
                     /locus_tag="HYQ63_RS20940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20940"
                     /product="cytochrome P450"
                     /protein_id="WP_179935336.1"
                     /sec_met_domain="p450 (E-value: 8.4e-32, bitscore: 109.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHGPLLRKITDYANRADPYPIYAELRKTPVVHEEDGPYVVSTYW
                     EIHALLHDPRISSDARNLDPRAAGEPADAETEAEEDDPGLPPAFLKLDPPEHDRLRRLA
                     MTPFGPPHTPRRIHAMRGELSRIVDELIDGFRDRDRIDLVDDFSYPFPVTVICRLLGVP
                     REDEPRFHTWADTLAASLDPDPEQDAAERRRVTQQARTELGRYLSELIEERRRSPGDDM
                     LSALVAGHGPDGRMSHTELLSTAALLLVAGHETTVNLITNGMLALLRNPDVLARLRAKP
                     HLAVPLVEELLRYDPPVQLLPQRTPLSDIDIAGVTIPKGASVWLVLASGNRDPQRFLDP
                     DRFDPQRRDNQHLGFGSGIHSCFGAPLARLEAQLALTALARRLENPRLREDPPPYRRNA
                     VLRGPRHLPITLDGLR"
     gene            complement(17015..18502)
                     /locus_tag="HYQ63_RS20945"
                     /old_locus_tag="HYQ63_20945"
     CDS             complement(17015..18502)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017241495.1"
                     /locus_tag="HYQ63_RS20945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20945"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_179935337.1"
                     /transl_table=11
                     /translation="MRCLVTGATGYIGGRLVPELLTAGHAVRCVVRSPGKLRDHPWAGR
                     VEIVRGDVTDEESVRAAMEGVDVAYYLVHALGGGPGFEETDRRSARLFGERARAAGVRR
                     IVYLGGLTPAGVPDRDLSPHLRSRAEVGRVLLDSGVPTAVLRASVIIGSGSASFEMLRY
                     LTERLPVMVTPRWVRTRTQPIAVRDVLRLLVGCAELPYEVSRAFDIGGPEILTYRDMML
                     RYAVVAGLPRRAILPVPVLTPGLSSLWVGLITPVPGTLARPLVESLRHEVVCAERDIRR
                     YVPDPPGGPLGVNRALELALRRIREADVATRWSSAATPGAPSDPLPTDPDWAGGSLYTD
                     HRRRAVNASPQEVWRVVESIGGENGWYALPLAWALRGWIDTLMGGVGLRRGRRDAARLR
                     VGDSLDFWRVEEVLPPRLLRLRAEMRLPGLAWLEMRVDRDAEGRTVFRQRAVFHPHGLA
                     GHLYWWGVSPFHALVFGGMARKIAAKAESSGVAVPLS"
     regulatory      complement(18575..18746)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    18792..18805
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.3"
                     /tool="antismash"
     misc_feature    complement(18793..18806)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.19"
                     /tool="antismash"
     misc_feature    18793..18807
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.08"
                     /tool="antismash"
     misc_feature    complement(18794..18807)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.24"
                     /tool="antismash"
     gene            18912..19208
                     /locus_tag="HYQ63_RS20950"
                     /old_locus_tag="HYQ63_20950"
     CDS             18912..19208
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003949502.1"
                     /locus_tag="HYQ63_RS20950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20950"
                     /product="type II toxin-antitoxin system VapB family
                     antitoxin"
                     /protein_id="WP_009716657.1"
                     /transl_table=11
                     /translation="MIFKRIGNGRPYPDHGRESTRQWADVAPRPVRLDQLVTTKQQLDL
                     ETLLAEDSTFYGDLFAHVVKWDGDLYLEDGLHRAVRAALQQRQVLHARVLELD"
     misc_feature    19277..19293
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.24"
                     /tool="antismash"
     gene            19323..19991
                     /locus_tag="HYQ63_RS20955"
                     /old_locus_tag="HYQ63_20955"
     CDS             19323..19991
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967678.1"
                     /locus_tag="HYQ63_RS20955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20955"
                     /product="LytR C-terminal domain-containing protein"
                     /protein_id="WP_179935338.1"
                     /transl_table=11
                     /translation="MSMLTPPGMGGKYRITGDRYPRMRRPRGRRRLVFAALGSVVALGL
                     VGWGTLQLIDVFSGGGKGGDTVRAARGSADCKREPGKGHDRSPGSSSRTAAKKLPKPSD
                     ITVNVFNATKRSGLAKDTAEELEKRGFKIGDVGNAPKAYDKKVKAPGILLGAPASADGT
                     FRVLSTQLTGAQTKNDTRRGKDVDLIIGSGFKDLVKAKDADKALTALTKPSPRPSGSPC
                     "
     gene            complement(20060..20695)
                     /gene="upp"
                     /locus_tag="HYQ63_RS20960"
                     /old_locus_tag="HYQ63_20960"
     CDS             complement(20060..20695)
                     /EC_number="2.4.2.9"
                     /GO_function="GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="upp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004943140.1"
                     /locus_tag="HYQ63_RS20960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20960"
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="WP_009716655.1"
                     /transl_table=11
                     /translation="MRIHVVDHPLVAHKLTTLRDKRTDSPTFRRLADELVTLLAYEATR
                     DVRTEQVDIETPVTATTGVRLSHPRPMVVPILRAGLGMLDGMVRLLPTAEVGFLGMIRD
                     EETLQASTYATRMPDDLSGRQVYVLDPMLATGGTLVAAIRELIARGADDVTALCLLAAP
                     EGVEVMERELAGAPVTVVTASIDERLNEHGYIVPGLGDAGDRMYGTAG"
     misc_feature    complement(20782..20795)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.46"
                     /tool="antismash"
     gene            20864..21064
                     /locus_tag="HYQ63_RS20965"
                     /old_locus_tag="HYQ63_20965"
     CDS             20864..21064
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015659393.1"
                     /locus_tag="HYQ63_RS20965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20965"
                     /product="hypothetical protein"
                     /protein_id="WP_123104650.1"
                     /transl_table=11
                     /translation="MADTDMPTGRTMGAVSARESAADRRRRRERFLRALNEARQVRDRV
                     RPRLTRAARMREAILLRTFRW"
     gene            21239..21775
                     /locus_tag="HYQ63_RS20970"
                     /old_locus_tag="HYQ63_20970"
     CDS             21239..21775
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009716654.1"
                     /locus_tag="HYQ63_RS20970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYQ63_20970"
                     /product="hypothetical protein"
                     /protein_id="WP_179935339.1"
                     /transl_table=11
                     /translation="MTSGRVTVYFAALLARTAEGWEASDTELDDVETLTDLIDLARGAA
                     KDDDTVLAFIEHEDAWFGVVRVDGEDDPHIYVSDAAAAARTSYGSMLTDELLGRDPDDD
                     LDSLVDLDGTEDGEPDQDDDADPDAPVPVGPLGDGDILTDLGMEEKELKALDGDALESI
                     ADMLGCSMEGLEAVR"
     misc_feature    22132..22147
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.25"
                     /tool="antismash"
ORIGIN
        1 cgcctcgtcg tcgcccatgg tgtaggcgcc gaatccctcg ccgaggtcgg ccacgagatc
       61 gacggcatgc gtcatgacgt cctccggaat agaagaaagc ggcgtgtcgc ttttcgcgag
      121 cagagggtcg cgagagggat cttcgcgagg ggagaaattc gcgttccggt gaacgtaatc
      181 cgcacgagag aaggcggcaa atatgcgttg ggtgtgacgt aatcacctct ggttatgacc
      241 tggaccacac tcgccgtctg cggcgtccgg tgcggcgcct accatgaggg cccgcccagc
      301 ccggaggacc gcccatggac accaggcgtc tgtactcgtt cgtgaagatc gtcgacgccg
      361 ggagcatcac gcgcgcggcc gacatcctgc acatcgcgca gcccgccctc agccagcagc
      421 tctccatgct ggagtcccac ttcaaacagc agctgctgat ccgcagcaag cgcggagtgg
      481 caccgaccga ggcgggccgg gcgctgtacc ggcacgccca gctcatcctg cgtcaggtcg
      541 agctggcgca ggccgccgtc gacgtgtccg ggcgggcgcc cgcgggcagc gtctcggtgg
      601 gcctggcccc gtacagcatg ggcgcggcgc tcgcgctgcc actgctcacc agcgtgcgcg
      661 agcgctaccc cgacatcgtg ctgcacatca acgagaactt cggcggggtg atcagcgagg
      721 cgatcatgac cggccggatg gacatggcgt tcatctacgg ggcggggccg ctgcggggcg
      781 tgcagttcga accgctgcgc accgaggacc tgttcctgat cgcggcgccg ggcaggacga
      841 cggagccggg cgggggcgcg gacgtcccgc tggaggagct ggcggacgtg gagctgctgc
      901 tgcccagccg catccacacc atccgtcagg tcgtggacgc cgcgttccag caggcgtcac
      961 tccagccgcg ggtgatcggc gagatcgagt ccgtcctgac gctggtcagc gcggtcggcg
     1021 cggacctggg ggcgacggtg ctgccgtggt cggcggcgcg cgcgatcctc gacgtgcaga
     1081 acctggtggt gcgccggatc gtgaacccga ccatcccggt caagctctcg ttgtgtacgt
     1141 ccgaccatca gccgctgtcg gagcccgccc atgccgtgca cgatcttttc catgaattga
     1201 tcgccgactt cggctgaagg tcggccagac gtccgccaga ggtccgcgtc tcagacgccc
     1261 gtggtgtcgg cggccgcgtc gaccgccgag gatgccaccc ggcccgaggc gggcttgcgc
     1321 agcagcagga gcgccgcgtc gtcgtgcagc cgcccgccca cgtgcgccag cagttcgtcg
     1381 tgcagcccgg ccagggtccg ggacggctcg tcggacacgt gcccgggcac ccgctcggcc
     1441 agcgggaagt acgcccggcc gtggtcgcgc gcctcgatga ccccgtcggt gtacagcagc
     1501 atctggtcgc cgtcggcgaa cggcaccacc tccaggctcg gcgcctcccc gcccagcgag
     1561 gccagaccca gcggcggcgc cgggcgcagc ggctcgacgg gcacgaccgc accggccggg
     1621 ccgatcagca gcggcggcgc gtggccgcag ttgacgatct ccatgcgccc gtcggcgggg
     1681 catccggcga caacggcggt gacgaagtcg tcgggggcga ggttgcgggc gaggctgcgc
     1741 tcgatgcggc cgacgacgtc cagcagatcc ggttcgtcgt acgcggcctc ccggaacacg
     1801 ccgagcacca gcgcggcggt ggacacggcg ggcagtccct tgccgcggac atcgccgacg
     1861 atcagccgga ccccgtacgg ggtggacacc agcgcgtaca ggtcgccgcc cacccgggcc
     1921 tccgccgcgg cggcgctgta gcggaccgcg acctggaact ggccgaccct cgcgggcacc
     1981 ggccggagca gcgcgttctg cgcggcctcg gcgaccgagc ggaccgcggc cagcacccgt
     2041 tcccggcgcc cgcgcaacac gctggccagg cagctcgcca gggtcaccgc gatgagcgtc
     2101 gacagcacga ccgcctgccc gtggaccggc gcggcctgcc aggcgccgag cgccgcgccc
     2161 agcgcgacgg cgaggaaccc gatccgcagc accgcccacg ggcggcacgc ggcggcggcc
     2221 agcgcggggc cgacggcgag cagcggcagc cagctcgtcc cgtctccggt gacgaaggcg
     2281 atggccgcga ccgcgcccag gatgagtacg ggcactccgg ccgcgaacgg tgcgggggga
     2341 tagggctggt ccagatgggt gcgggcctgg atcatgtccg ggtcgactgc tctctctcgc
     2401 tcgccgggtt cactcgaata cggcgtgatg tccgtttcat ccagagaacc agcgcttcgc
     2461 ggcgagcgac aagggccgga atttcagata gtgagcgaaa ggctcctggt cacgcggtcg
     2521 gccgtcggca acagccgctc gcgtatctcc tccagccgcg cggcccggtc cgcccgaccg
     2581 gcctgaccgg ccagacccgc ccggccggcc tggagcgaca ccccgagcga cccgagccgg
     2641 tccccgctgt acacgggcac cgcgaagcag accgtgccca gcgcgtactc ctccaggtcg
     2701 gtgaccggct ggtcggcggc cgaggcgtcc agccgccgca gcagctcggc ggggcgggtg
     2761 acggtgcggg gcgtgaggtc ggcgagcgga tgccgggaca gatagtcgct gcgggcctcg
     2821 tcgcccagct cccgcagcac gcacttgccg agcgcggtgg cgtgcccggc gtcctcgaac
     2881 cccacccaca gatccacccg gggcgcccgg gggctgtcga cgatctccgc gacccggatc
     2941 tcgccgtcct cgtagaaggt cagatacgcg gccgccgaca gctcgtcccg cagcccggcc
     3001 agcgccggcc gcacccggtt gagcagcgcc tgcccgcggc tgccgacctg gagcgtgtgc
     3061 agcttgtcgc cgacgacgaa accgccgtcc ggcagccggt gcacatagcc gtcgtggacc
     3121 agggtccgca gcaggtggta cgtggtggcg agcggcaacc ccacctcccg agccagctgt
     3181 ttcgccggcg caccgccctc atgtgcgccc acggcctcca tcaggcggaa ggctcgctgc
     3241 acggaagtga tgagcgtagg gcctcctgga gtacccatat gaccagcttg cgcccggtac
     3301 ggcggccggg caagggcgta tctgcggccg ggacgcgcga gggcgtcggc cgacccggat
     3361 agtcggccga cgccctcggt ccggagcgaa ggcggtcagc cggggctgat gcggccccgc
     3421 cagcccccct cttcctggcc ccggtgctcg atgaagtcct tgaaccggtg cagatcgccc
     3481 ttgatccggc ggtcgagcgt cccggtcatg tccgcggcct tctccgccat tccggtcggc
     3541 tcgaagacca tggccagatt gacctcggtg tgggtggcat ccagggaccg gaaggtcacc
     3601 aggccctgct gctgcacgtc gcccgaggtc gtacgccagg cgatgcgctc gtcggggagc
     3661 tgatcgacga tctcggtgtc gaattcgcgg tgcacaccgg cgatggaagt cgaccagtgg
     3721 ttgtgacggt cgtccacctg ggtcacctgg tccacgcctt ccatgaaccg cgggaactcg
     3781 gtgaactgcg tccactggtt gtaggccgtg tgcagcggaa cctcaacctc gacggtctcc
     3841 cgcacggtgc tcatcggtga ctcctttcga cgctgtcacc gcaccgggta accgtgcccg
     3901 cgcacgtaaa acgtcagcgc aggggatgca gcgcggccag ttcggcgggg gcggtgccgg
     3961 tcgcgatggc gtcggccagc agccgaccgg tgagggggcc gagggccacg ccccacatgc
     4021 cgtggccgcc gttcacgtac acccgcggcg aggcggtcgg accgaccagc ggcagcccgt
     4081 cggcggtgca cgggcgcgag ccgacccact cgtccgtacg ggcgtcccag tcgacgtccc
     4141 gcagcagcgg acgggccgcg gcgatgatcg cctggatgcg gcgcggatcg acgggccgct
     4201 ccgggggcgc cagctccatc atcccggcga cccgcacccg gccgtcgccc agcggggtgc
     4261 acaccacctt ctgcgcggcc agatacgtcg ggcgcgccgg tgcgcccgcg gcgggcacgc
     4321 tgaagctgta cccgcgcccc gactggacgg gcacccgcac cccgaacggg cggaccagcc
     4381 ggttcagcca ggtcccggtg gagacgacgg cgacgtccgc gcgcagatcg ccctgcgacg
     4441 tgccgaccgc gacccccgtg cccaggtcgc ggatgccgga tacttcggcc cgctccacga
     4501 ccttcccccc gcgctcccgc accgcgtccg ccagcgcccg cacgaagttc ccggggttca
     4561 gccgccgctg cccgtgcagc gcgatgcccg cgccgaccgc gtcgctgagc accggctcca
     4621 gggagcgcgc acggtcgccg tcgatggcct cgtacggaat ctcgtacccc gccgcccgcg
     4681 cgtgctccag ctcctccacc atccccgccc gctcggccgc cgtaccgaac gcgagcagca
     4741 tcgggtccac cgggacggtc ggctcctcga caccgcccgc cgcgagatcg tcgtacgcgg
     4801 cgagcgcgtg ccggttcagc gcggcgaacg tggtggccag cacccgccag cggcgcgggg
     4861 tgcagtgccg ggtgaacgac agcaggaagc gcgccaaccg cggatcggcc cgcggcggga
     4921 tgtagacggg cgaggtcggc gtgaccagac tgcgcacccc gtaccgcagc gcggcgggct
     4981 cgggcaacgg catggcgagc gccggcgtca gccaccccgc gttcccccac gaggccccgg
     5041 ccgccggtcg ccgccgctcg gccaccgtga cctcgacacc ccggccctgt agggcccacg
     5101 cggtggcgag cccgacgatt ccggcaccga cgacgacggc gctgcgtggt gtggacacgg
     5161 tggcgttccc cttcccctgg cttcccctgg attccccggt gttgcgtgct gcgtacgcat
     5221 catgggcggg cgggggcgcg cgccgcactg tcctggggac cgattgcacg ggggcgggtg
     5281 ttgtcgcacg gcacaagccc gcgacgcggg cccggcgtcg cctacgggag gcgcagcgct
     5341 cgtaggcgca ggcgcagctg gatctcgaac ttggcggccg ggtcggcgag gtcgaggccc
     5401 gcgatctcgt gtgcgcgccg caggcggtag cgcagcgtgt tggggtggat gtgcagctgg
     5461 cgggcggcca gccgggcgtc ctcgccggcg gcgaggtagc gggccaggct gtcgagcagt
     5521 tccgtgccgc gctcgcggtc gtaacgctcc agctcggcga tcgcgcccag cgggtcgtgc
     5581 ccggactcgt cggccaggtc gaccgtctgc atgagcagcg cgtccaggtg gacatcgcgg
     5641 atgtgggcgg ccgcgccgcc cgagccgccc agccgggtga ggaggcggac gaccaggtcg
     5701 gcgtcggccc gggagcggtc cagcgcgtcg gggccgggga cggtacggcc caccccggcc
     5761 accagcccgg accggtcctg gagttcgcgg acgacgcgcg ccagccgctg ttcgtcgcgc
     5821 accggcagca cggcgtagcc cgcgccgtcg gcctccgcgt ggacaccgcc gtgcgccgcc
     5881 ccggccggtc cggcgaaccc cgcgaacccc gcgagcccgt cgagcccggc gagcgcacgc
     5941 cgcagcggct cgccggacgc ggccggggtc accggccgca gcgcgacgac ggccagcggg
     6001 ccgggcgcca gcggcagttc ggcggcggcc tcgaccgccc ccgccccgcc ggccagcagg
     6061 gcgcgtacgg ccgcggcccg ccgcgcctcc tccccgcgcc gccgcgcgat ctgccgggcc
     6121 agcaccggag ccgccagcgc ggccgcctcc accagggccg cccgctgctc ccgggagggc
     6181 gcggtcggca cgatcgccca gatggaaccc acggacaggt cgtccacccg gatcggcatg
     6241 atcgcccgcg gcagcacatc gggcgccccg gacgcccgga agtccgcgta gagcgggacg
     6301 gacgagcccg ccagccgcac atccagccgg tcgttgcgca gcagcggccg gtaccggtcg
     6361 ggcacccggc ggctgaggat ggtcgcgaca cgggcgtcgt ccgagtactc ctggccgggc
     6421 gagtaggtga tcaactcgga agcgtcgtcc tcgatggtga ccggcgcgcc gacgagcccg
     6481 gcgatgctgt tggccagggc gaggaggccg tccggggagt cgtcgtacat ggctcctccg
     6541 ctcatgagcg cgccgacggt tccgggggcc actacccgga ccgggccgta tcgatgcgct
     6601 gaggcgggga ttgtccatgg acgtgccgtt acgcgccccg ctacccgatc gccccggtcg
     6661 actccgggcg gcgccgcccg tatccggtgg cctgctcgaa ggcgtggccg atctggagga
     6721 cggcgaagtc cgcccggtgc ggtccgacga tctggagacc caccggcagc ccggcgggcg
     6781 tgaacccggc cgggacggac agggcggggc tgcccgtcga cgtgaccagg tacgcggaac
     6841 gcatccactc caggtagtcc cccatcgcca cccccgccac ctcggtcggg tactcgatgc
     6901 cgatgtcgaa cggcggcacc tggctgaccg ggagcagcag cacgtcgtag cgctcgaaga
     6961 aggcgcggac gcggtggaag agcgcggtgt gcagcacctc ggcgcgggcc acctcgggcc
     7021 cggtgaggcg gcgccccgcc tccgcgttct cccggatcgt ccgcttcagg ccctccgggt
     7081 gacggtccat gagcgggccg aacgcgacct cgaacagcgc ggcccgctgc gtacggaaca
     7141 cctcctcgcc ctccgacagg tccgggcacg cccgctccac cacgcacccg aggtcctcga
     7201 agacccccgc cgacgcctcc acgaccgccg ccacctccgg ctccaccggc accagcccgc
     7261 ccaggtccgg cgaccaggcc acccgcagcc cggtcagatc ccggtccagc ggccgggcga
     7321 accgggcgcc cggctcctcc agcgcgatcg gcgaccgggg gtcggggccc gccatcgcgg
     7381 acagcagcag ggcggtgtcc gcgaccgtac gggccatcgg gcccttgacc gagagcgtgg
     7441 tccacgcgtt cgccgcgggc caggtcggga cgcgcccggg cgacgggcgc agccccacca
     7501 cgttgttgaa cgaggccggg ttgcgcagcg acccgccggt gtcgctgccg tccgcgatcg
     7561 ggaccatgcc gctggcgagc gcggcggccg cacccccgct gctgccgccc gcgctgcggt
     7621 cgagtgcgta cgggttgtgg gtggcgccga agatcgggtt gaaggtgtgc gaaccggcgg
     7681 cgaactcggg cacgttcgtc ttgcccaggg tgatcgcccc ggcgtcccgg atgcgctcga
     7741 tgatcaggtc gtcctggtcc ggtacgccgt cgaccagcgg cgaaccgtgg ctggtgcgga
     7801 tgcccgcggt gttgtgggtg tccttgtgcg cgatgggcag cccgtgcagc acccccaccc
     7861 cgtccgcccc cgccgccacg atccgctcgt cggccgcggc ggcggcgtcg agcgcgcggt
     7921 ccgcgacgag ggtgacgatc gcgttgacgt cggggttgac ccgctcgatc cgctcaagat
     7981 gcgcccgcac cacctcccgc gccgacagct cacgcccccg caacagggcg ctcagctcgc
     8041 gcgcggtctt gtagcacagc tcgtcgtcgt ggtccgtcac ggtggctcgc tctcgtagct
     8101 cgtcggattg tccccacccc actcctcccc cacggtgagc ggttatccgc gggggaattc
     8161 gtcggcccgc cgcgcggcgg tggctgcggg agtgcgcggg gcggaggccc ggtcaggggc
     8221 gggagcggac cgggaagggg cggggcgggg gaacagcaac tgcaccagca gcgccaccgc
     8281 cacgttcacc cccagcccca ccagcccggc gttcacgtgc cgcacatcca cctcggccag
     8341 cgtcagccac gtcaccacgg cctcgcccgc cgccagcccc gccagggcgg cccgtgccgt
     8401 gaggaggcgg cgtcggccga ggacggcgag caggccgggg acgagctgga tgaagccgct
     8461 caccgtgagc agttgcaggt cggccaggag gccggggcgc aggatgccga gggtgagggc
     8521 caggccgatg gccaggacga cgacgctgtg gttgacccgc atgcgggccg actcccggcc
     8581 cgggggcagc aggttctggg cgaccagggt ggagatgccg atgcacatcg ccccggccgg
     8641 aaccatcgcc gaggccgccg cggcgaccac gacgagcccg gtggcccagt ccggcagggc
     8701 gccctgggcg agggtgagca gcaccccgtc gccgtcgccg tcgacccgcg cgaccacccc
     8761 cgtgagcccg atcatgatcg ggatcatcag cgcgacctgg tacagcggca tgaagatgtt
     8821 gttcgtacgg atcgcccgcg gcccgcccgc ggccatcagc ggcggccagt ggtgcggcgt
     8881 cgccatcatc ccgcccgcga tcgccgagac cagcacgctg gtggtccacc acacctggtc
     8941 ctgcgccccg ccgtgcacgg tcagcatctg cggctgcacc tcgtggaccc gccggaacac
     9001 ctcgcccacg ccgccgccga cgtagtgcag cgggacgacg acggcgagca ccgccatgac
     9061 gccgaccgtc aggacgtcct tgaagtaggc gctgttcttc agcccgcgga tgccggacca
     9121 cagcacgaag gcggccgtca gcaccgaggc cagcaccatg ctcagccgcc ccgacgccgt
     9181 acttccggtc accagcccga cgaccatgcc gagcccggtg agctggagct ggatgtaggg
     9241 gagcaggaag atcagcccga tgaccgcgac gaccttgccg aacagcgggc tgcggtagcg
     9301 gtcggtgaag tagtcggcct gggtgaggta gccgcgttcc ttgcccagcc gccacagcct
     9361 cggctggacg aagtagagca gcaggaaggc gagggccagg tagacgacgg cgtacgtggc
     9421 ggcgttgccg ccggtgaacg cgacccccgc gaccccgagg aagctgaagg tggtgaacac
     9481 ctcgcccgcc tggaggaacc acatggcggc ggtgccgaag ttgcgccgtc cgacggccca
     9541 ttcggcgagg tcggtggagc gcccggtccg gccgaggaag ccgcagaggg cgagggcgca
     9601 catgcccagc agcgatacgg cgaggacgac gctcactgtc cctcacccgc cgccgcaccc
     9661 gccgccacgc gctcaccgtg ccggaacagc ccccactcga cggcggccag cgccggggtg
     9721 agcgtgagca cccagccgcc gacccagacg tacagcgagg gcatgccgaa ccacagccgc
     9781 tcggcgttga cgaacggcag ccacaccgag gcgagcaggg ccagcgccgg gaccacgggg
     9841 agaaggacga gcagtttgcg ccgcgacacg gtacctccag ggcgcgaggg gactgcgcgg
     9901 cattcaacag acccgccccc gcgtccggca tcgtcaccgg cggccaacat gcggcggccc
     9961 cgccttgtcc gcggggacaa ggcggggctc cacaaggtcg ctaccggccc gcgcccaccg
    10021 gaagccgcgc ggccgacgtc ccaagacccg tcggtccgaa cagctgccgc ggcgccccgg
    10081 cctcgtgccg cagctcctcc tcccggtacc gggcgacctc ccggtgccag gtcaggatcc
    10141 cggtcatcca gttctggagg tcgcgcacat acccctccag ggccgcccgg ccctgcgccg
    10201 acagcccgaa gtcctcgtac aggaccggga actcatgggc cgcgacgtgc tggaactgcc
    10261 gcatccgcga ggtcatcagg tcctgcacga tggccacccc ggtcgggtag tcgcagtcga
    10321 agaagttctg cacgaccagg acgccgttgt ggacctcgcc ctcgaactcg atctccttct
    10381 ggtacgagaa gacgtcgttg agcagggtgg cgtagtccat ggcggcgctc tccagcgaac
    10441 ggaccggccc gctgtcgcag atcccgggcg ggacgcgcct cccgtatgcg agtcggcaca
    10501 ggctcatggt gaggccggag ccgaaggtgt ggcggcgcat ctcgatgtag tcgatcgggt
    10561 cggggatccg gtgctgcgcc tggttggcca gctcccacag ccagctgtcg agcatgtcgt
    10621 cgacggcctg gcggaacgcg cggcgcgcgt cctcctccat cggtcccgcg gtacgcgacc
    10681 acaggtcggc gaggccgcgc tccagcccgc ccgcggggac gggggtgggg cccgcgtcga
    10741 ccggcatgaa cgtcttgagc cgctcgttgc acgcctcggc gccggtgagg tcccgcttcc
    10801 ggccgaagac ctgcggatag tagtcgtccg cgtaggttcc ccaggtgagc cagcccgacg
    10861 tcagatccag ctcgtcgggg gacgcctccg ggtggatacc cgccgcgcac agcggaaggt
    10921 cggcggcgcg cagccggcgc tcgtcccaga cgtccgagtc ggggacgccc ggctggggcc
    10981 cgaagatgcc catccggtgc gtccactcga ccagattgcg gcgcgcccgg tccagatgcg
    11041 ggctgagccg ggcggtgaac ggcatgaaga agtccggcag ccgggacggc ccgacccgct
    11101 ggtgcggcac atggctgaaa ccgcgcgccc gggcccgctc cgcccggccg gtggtgagcc
    11161 gtatgtcggc ggccgatacg cccaggccgc tgccacccgg gccaccgacg ccgaggccgc
    11221 cgatgccgag gccgctcacg gagaacggcg accaggcggg ctcggccgcg gcccctccgc
    11281 cgttcatgta gcggctggac cgcatgtgcc actcatggcc gcccgactgc cagtcctgga
    11341 gccccttgac gtacgccatg acgcccgcgc atgccgccgc gtccaggccg tgctcggcga
    11401 acagcggggc cagctcggtg aacgtggtgt tctcgaactg ctggagccgc gaggtgagca
    11461 ggtcgttgac ggcgtccgcc gcctgctggg tggtgcagcc caggaacgtc tccaggacca
    11521 gcaccccgtt gctccgctcg ccctcctcct cgatctcccg ctggtacgag aacaggtcgt
    11581 tgcgcaggtg taccgcgtcc gcgaacgcgt cccgcagcac gcgcagcggc cgcgactccg
    11641 cgatcaccgc ggggacctcg gcccccaccg cgtgctccac gagccccgcc gaccacgggg
    11701 cgccgccgac cttgcggcgc atctcgatgt actccaccgg attgggtgtc cgccctgcgt
    11761 tgatgttgga cagctcccag agcgactcgt tgagcaggtt ctccgtggac tcccggaacc
    11821 gggcccgcca gtccggcgac atcgcgggca ccgtccgcac ccacaggtcc ttcagccccg
    11881 cctcgaccgg gttctccggt tccggcatcc cggccgccgc cggatccatc ggcatgaaca
    11941 gcggcagccg gtccaggtac gccttgccgc ccgcacggtc ctgcgagcgc ttgaaccgct
    12001 ccaggaagtg gtcgtcgaag aagaacaccc acacgtacca gtccgtgatc agggccagtt
    12061 ccgcggcgga gcagtcgggg tgggtgtagg cgcacagcag ggcgtagtcg tgggcgtcga
    12121 gatcctcctg ctcccagatc ccggagcctt cgagcattcc cctctcgcgg gcccagcggg
    12181 tggagtgctc ccgtgcctcc tcgacgtggg gattcagccg cgccgggtac ggcatgtaga
    12241 agtcggggag ttgaaagggc tgtgtcactg gcgggccggc acctctccgt acgacggttg
    12301 cccgcgcggc cggaaacagg cccccgcggg ctggtcggct cggccctacc cagggccctg
    12361 acggcctatc cgacagaccg atcagtcaca tgaatgtgcg atcgtttccg gccccgccac
    12421 ggcggtacgg ccgaggcggg accggaaacg gcaggtcgtg cgcgcgctat ccgggcggtc
    12481 tcgtggcctg ggccgggacg accgcccgcg gcgtcgcggc ggaccgcgcc acgacggccc
    12541 ccgggccgga tccgcccacg gtggcccccg gcccggatcc ggccacggcg gcccccgaac
    12601 cggcggcggc aggccccgcc ccgggcccgg cagccggaga ccccgccacc gaccggaagg
    12661 cccactccat ccgcggctcc atcgcgaatc gcaacgtccg ctgcacgagc ggggagcaca
    12721 gcgcggtcac caccaccgcg gcgatgaccg tgaccgcgat cgcgcccgcc ggggtgtgca
    12781 gccaggacgg gtcgtaccac cccgcgaagt gggagccctt tatgagcagg ccgtgcagca
    12841 ggtacccgta cagcgttccg gcgccgagcg cggtgaacca catcgtccgc cccggcaccc
    12901 aggcgaagaa gcacgcggtg agcaccatgg agcagccgaa gagggcgaac gtcatcacga
    12961 tgccgctcca ccacggcgcc cccatctcct gggcgctgtc ccggtggtag aaccacccgg
    13021 cgttcatgcg cggcaccgcc cagtacgtga agaccagcgc ggcggccgcc acgggcaggg
    13081 ccaccatccg cacctcccgc cgccgcacca tccggaagtg ctccggccgc atgtgcagtc
    13141 ccgccacgaa gaaggggagg aactggagca cgcgctgaag gtcgagatcg tcgccgatgt
    13201 cgggcgagca cgaggcgagc gcggcgatcg cgagcgcgag cggcaccgga tggcgcgcga
    13261 tccgccacac cggggtggtg acccgccaca cgaagagcgc gatcaggaac caggtcagat
    13321 accaagggtc gagcaggctg atcgggtacg aggggtcgcc gcccgcccag cccctgagga
    13381 ggctgtacac ggactcgaag atcacgtacg ggacggcgac cccggtgagc aggcgcttca
    13441 gccgatccgg ccggaggtcg aagttccgcg agaagtagcc ggagatgagg atgaacgccg
    13501 gcatgtggaa ggcgtagacg aacatgtaga gggcggacgc cgctctgctg ccgtcccgca
    13561 gcggttccca ggaatgcccc atcgcgacca gcacgattgc caggtacttg gcgttgtcga
    13621 agaacgcgtc ccgctgcttg ggggctgcgg aggacgaggg gacggacacg gggacgggcg
    13681 ggcggacggg tggggggacg ggcccggggg cgggggcgcg ttgcgcgcga cgtaaggacg
    13741 agatgttcat cacatacgcc accccatgga accgacagcg gcgatcccgc ctctttgtgg
    13801 ggttgaggag agggctgcgg agtggaacat tccacgcacg gtagtggcgg ccacagggcc
    13861 acgggcggaa tgactcagct cttgcgcaac gaccgttcac gcccccgccc ccactggcac
    13921 actgcgcccc cgcacccgca cccgccgccg caccgcacgt cgcgccgcac cgcctgactc
    13981 gcccccgtcg cccctttggc ccggctgtgc gcgcgggccc cggccgcctc gcccatgctg
    14041 ggcccaggag ggggcgaccc ggcgacccga ggcgtgcgaa gggcagggcc cgatgaggct
    14101 tgtcgtcgat ctcaaccgct gccagggata cgcgcagtgc gcgttcctcg cccccgacgt
    14161 cttcaccctg cacggcgagg aggcgctgct ctacaccccg cacgcggacg acacccagcg
    14221 ggagaacgtg gcgcgcgcgg cggcggcctg cccggtccag gccatcctgg tcgagggtcc
    14281 ggacgatgac ctggtcgacg gcccggtcgg cgacgagggc ctgtccggtg tccgctgacg
    14341 gcgcgccgca cacgctgcgg cgcgaggggc gcatcgtgat cgtcggcgcc tcgctggccg
    14401 ggctgcgggc cgccgagaca ctgcgcgacg aggggttctc cgggtcgctc acgatcatcg
    14461 gtgacgagcc ccacgagccg tacgaccggc cgccgctgtc caagcaggtg ctgctgggcc
    14521 gggcccccgc cgaccacacc acgctgcccc ggcgccgcga ggtgtacgcg cggtggcggc
    14581 tcggcgtcgc cgccaccggg ctggacatga ccgcccgccg ggtgcggctg gccgacggcg
    14641 acgaggtcgg ctacgaccgg ctcctgatca ccaccggggt gcgcgcccgg ccctggccgc
    14701 accccctgga ggccgagctg gacggcgtct tcgtgctccg tacccgcgag gacgcggccg
    14761 cgctgcaccg ccgcctgtcg gccgcaccgc gccgggtgct ggtcatcggc gcgggcttca
    14821 ccggctcgga gatcgcctcc gcctgccggg agcgggggct gccggtcacc gtcgccgaac
    14881 gcggccccac ccccctggtc ggcgccctcg gcggggtgct cggcgaggtc gccgccggcc
    14941 tccagcgcgc ccacggcgtg gacctgcgct gcggcgtcat ggtcaccggg ctggagggcg
    15001 acgccgccgg gcggctgcgg cgggcccatc tgtccgacgg caccgccctc gacgccgatg
    15061 tcgcggtggt ctccctcggc atcacccgca acaccgaatg gctggccggt tccgggctgg
    15121 gcgccgggcc ccgcgggatc gcctgcgacg cgggctgccg cgccttcgac gtacgcggca
    15181 tcgtcaccga cgacatcttc gtggccgggg acgtggcccg ctccccgcat ccgctcttcg
    15241 gctaccagtt cctgtccctg gagcactggg gcaacgcggt cgcccaggcc gagatcgccg
    15301 cccacaacat gatcagcgcg agcgccgacc gccgtccgca tctgtgggtc ccggccttct
    15361 ggtcctccca gttcggggtg aacatcaagt cggtcggggt gccgtcgatg ggcgaggagg
    15421 tcctgatcgc gcaggggtcg ctcgccgagc gccgcttcac cgcggtctac ggataccagg
    15481 ggcgcgtcat cgccgccgtc accttcgacc agagcaagtg gctggcgttc taccagcggc
    15541 tgatcgagac cgccgcgccc ttcccgccgc cgttcaccac cgtcgaccgc cgcaccgagg
    15601 ggctgcggcc cgtccccgcc gacttcccgg accccacgct gcccacccac ggcccgaccg
    15661 tcaccctcag cggctactcg ccctccgacc ggcggatcgc cttcaccccc tcgcgcgtct
    15721 gaccaccccg atcccctgcc cccgtccctg atccccggaa ggactccgcc atggcccacg
    15781 gccccctcct gcggaagatc accgactacg ccaaccgcgc cgacccgtac ccgatctacg
    15841 cggaactgcg caaaacgccc gtggtgcacg aggaggacgg cccgtacgtc gtcagcacct
    15901 actgggagat ccacgccctc ctgcacgacc cgcgcatcag ctccgacgcg cgcaacctcg
    15961 acccccgcgc cgccggggaa ccggccgacg ccgagaccga ggccgaggag gacgaccccg
    16021 ggctgccgcc cgccttcctg aagctcgacc cgcccgaaca cgaccggctg cgccgcctcg
    16081 ccatgacccc cttcggcccg ccgcacaccc cccggcggat ccacgccatg cgcggcgagc
    16141 tgtcccgcat cgtcgacgag ctgatcgacg gcttccggga ccgggaccgc atcgacctcg
    16201 tcgacgactt ctcgtacccc ttcccggtca ccgtcatctg ccgactgctg ggcgtcccgc
    16261 gcgaggacga accccgcttc cacacctggg ccgacaccct cgccgccagc ctcgacccgg
    16321 accccgaaca ggacgccgcc gaacggcgcc gcgtcaccca gcaggcgcgc accgaactcg
    16381 gccgctacct ctccgaactg atcgaggaac gccgccgctc ccccggcgac gacatgctct
    16441 ccgccctcgt cgccgggcac ggcccggacg gccggatgag ccatacggag ctgctgagca
    16501 ccgccgcgct gctgctggtc gcgggccacg agaccaccgt caacctgatc accaatggca
    16561 tgctcgcgct gctccgcaac cccgacgtcc tggcccggct gcgcgccaag ccgcatctgg
    16621 ccgtccccct ggtcgaggag ttgctgcgct acgacccgcc cgtccagctg ctgccccagc
    16681 gcaccccgct ctcggacatc gacatcgccg gggtgaccat ccccaagggc gcctccgtct
    16741 ggctcgtcct ggcctccggc aaccgcgacc cccaacgctt cctcgacccc gaccgcttcg
    16801 acccccagcg ccgcgacaac cagcacctcg gcttcggcag cggcatccac agctgcttcg
    16861 gcgccccgct ggcccgcctg gaagcccagc tggccctgac cgcgctggcc cggcgcctgg
    16921 agaacccccg cctgcgcgaa gacccgccgc cctaccgccg caacgccgtc ctccgcggcc
    16981 cccgccacct ccccatcacc ctggacggcc tgcgctagct caacggcaca gccaccccgg
    17041 acgactcggc cttggcggcg atcttccggg ccatcccgcc gaacaccagc gcgtggaacg
    17101 gcgagacgcc ccaccagtag aggtgcccgg ccagcccgtg cgggtggaag acggcgcgct
    17161 ggcggaagac ggtccggccc tccgcgtccc ggtccacccg catctccagc cacgccagcc
    17221 ccggcagccg catctcggcc cgcagccgca gcagacgggg cggcaggacc tcctcgaccc
    17281 gccagaagtc gaggctgtcc ccgacccgca gccgggccgc gtcgcggcgg ccgcgccgca
    17341 gcccgacgcc gcccatcagg gtgtcgatcc agccgcgcag agcccaggcg agggggagcg
    17401 cgtaccagcc gttctcgccg ccgatgctct ccacgacccg ccacacctcc tgcggggagg
    17461 cgttcacggc gcggcggcgg tggtcggtgt agaggctgcc gcccgcccag tcggggtcgg
    17521 tgggcagcgg gtcgctgggg gcgccggggg tggcggcgga ggaccagcgg gtggccacgt
    17581 ccgcctcgcg gatccgccgc agggccagct ccagggcccg gttcacgccg agggggccgc
    17641 ccggcgggtc gggtacgtaa cgcctgatgt cccgctcggc gcagaccacc tcatgccgca
    17701 gcgactccac caggggccgg gcgagggtcc cgggcacggg ggtgatcagg ccgacccaga
    17761 ggctggagag ccccggggtg agcaccggca ccggcaggat ggcgcgccgg ggcagcccgg
    17821 cgacgaccgc gtaccgcagc atcatgtcgc ggtaggtgag gatctccggg ccgccgatgt
    17881 cgaaggcccg gctcacctcg tacggcagct cggcgcagcc gaccagcagc cggagcacat
    17941 cgcggacggc gatcggctgg gtgcgggtgc gcacccagcg cggggtgacc atgaccggta
    18001 gccgttcggt cagatagcgc agcatttcga acgacgccga gcccgacccg atgatcacgc
    18061 tggcccggag caccgcggtc ggcaccccgg agtccaggag cacccgcccc acttcggcgc
    18121 gggaccgcag atggggagag agatcgcggt ccgggacccc tgccggggtc agcccgccga
    18181 ggtagacgat ccgccggacc ccggcggccc gcgcccgctc gccgaagagg cgcgccgagc
    18241 gccggtcggt ctcctcgaag ccgggcccgc cgcccagcgc gtggaccagg tagtacgcga
    18301 cgtccacgcc ctccatggcc gcccggacgg actcctcgtc ggtcacatcg ccgcgtacga
    18361 tctcgacccg ccccgcccag gggtgatcgc gcagcttgcc aggggaacgg accacacagc
    18421 gcaccgcgtg ccccgcggtc agcagctcgg gaacgagcct gccgccgatg tagccggtgg
    18481 ccccggtgac cagacagcgc atgcggccat gctcgaacgc acgggggccg cccgcaagcg
    18541 gggggggcgg cggcagccgg ggccgggcag cacaaaacct gcgaggtggg ctcccttcgc
    18601 cggcattgtc cggatcaggt tgtggaggtc gccttccggt ctccccgacc ttccggcctc
    18661 tcagcccggc catcaacgag acgttccgga gaaccaaagt cctctgtcct gagcgcctct
    18721 ccggtcgagc tccctcgctc gccccgcagg ctgatattca ggttactcct gacccccttg
    18781 ggcgactagt cccttttcga gaaaattcca cccttttgcc agcgcgtcgc ggagcgccct
    18841 ccccgggccc ccggcctggc actcccgcgc cttggctgcg ccggaagccg cttgcccggt
    18901 aggctttccg tgtgatcttc aagcgcatcg gaaacggtcg accctatccc gaccacggcc
    18961 gggaaagcac ccgccagtgg gcggatgtcg ccccacgccc ggtacgtctt gaccagctgg
    19021 tcacgacgaa gcagcagctc gatctggaga cgctgctcgc cgaggactcg acgttctacg
    19081 gggacctctt cgcccacgtc gtgaagtggg acggcgacct ctatctggag gacgggctgc
    19141 accgcgcggt gcgcgcggcg ctccagcagc gccaggtgct gcacgcgcgc gtcctggaac
    19201 tcgactgacg ccgtcccggc gaggggtgac cgggcctccg cattggccct ttcgggttgg
    19261 actgcacacc aaccattgat catttagtag gcatcgtcac caggccgcac tacgctgcgc
    19321 acatgagcat gctgacccct cctggcatgg gcggaaagta ccgcatcacg ggcgaccgct
    19381 acccgcgcat gcgccggccc cggggccgcc ggcgcctggt gttcgcggcc ctcggctcgg
    19441 tcgtggcgct cggcctggtc ggctggggaa cgcttcagct catcgacgtc ttctccggcg
    19501 gcggcaaggg cggcgacacg gtgcgcgcgg cgcgcggcag cgcggactgc aagcgcgagc
    19561 ccggcaaggg ccacgaccgg agccccggtt cgtcgtcccg tacggcggcg aagaagctgc
    19621 cgaagccgtc cgacatcacc gtcaacgtct tcaacgcgac caagcgctcc gggctcgcga
    19681 aggacaccgc cgaggagctg gagaagcgcg gcttcaagat cggggacgtg gggaacgccc
    19741 cgaaggcgta cgacaagaag gtcaaggccc cggggatact cctgggcgca ccggcctccg
    19801 ccgacgggac cttccgggtg ctctccaccc agctcaccgg ggcacagacc aagaacgaca
    19861 cccgccgggg caaggacgtc gacctgatca tcggctcggg cttcaaggac ctggtcaagg
    19921 cgaaggacgc cgacaaggcg ctcaccgcgc tgaccaagcc ctcgccccgc ccctcgggct
    19981 cgccctgctg agcgggaccg gctgaacggg accgggcggg tccagcccgc gccgccccgc
    20041 tgaaggggac cgggcgggtc tagcccgcgg tcccgtacat ccggtcgccc gcgtcgccga
    20101 gccccggcac gatgtacccg tgctcgttga gccgctcgtc gatggacgcg gtgaccaccg
    20161 tcacgggcgc gcccgccagc tcgcgctcca tcacctcgac gccctcgggc gccgccagca
    20221 gacacagcgc ggtgacgtcg tccgcgcccc gcgctatgag ttcccggatc gccgcgacga
    20281 gcgtcccgcc ggtcgccagc atcgggtcca gcacgtacac ctgacggccg gagaggtcgt
    20341 cgggcatccg ggtggcgtac gtggacgcct ggagcgtctc ctcgtcgcgg atcatcccga
    20401 ggaagcccac ctcggccgtc ggcagcagcc gcaccatgcc gtcgagcatc ccgaggcccg
    20461 cccgcaggat cggcaccacc atggggcgcg gatgcgagag ccgcaccccg gtcgtcgccg
    20521 tcaccggggt ctcgatgtcg acctgctcgg tccgcacatc gcgggtggcc tcgtacgcga
    20581 gcagggtcac cagctcgtcg gcgagccgcc ggaaggtggg ggagtcggtg cgcttgtcgc
    20641 gcagcgtggt gagtttgtgc gccaccagcg ggtggtcgac gacgtggatc cgcatggcaa
    20701 cgacactaac ggagccctcc gaccgcggct cccgccggta accctccggc gcgcgccgac
    20761 agtctgtcgc tgtactggca tcaaaccgcc gtttcggggg aaagtgggca ggagcgcccg
    20821 ggccccacgt ccgggcggag acctcggccc gaggggtgag gccatggccg acaccgacat
    20881 gcccaccggc aggacgatgg gtgccgtgtc cgcacgcgag agcgccgcgg accgccgccg
    20941 ccgtcgcgaa cgcttcctgc gcgcgctgaa cgaggcccgg caggtgcgcg accgcgtacg
    21001 gccgcggctg acccgcgccg cccgcatgcg cgaggcgata ctgctgcgca cgttccgctg
    21061 gtgaacccga acccggcgca ccgttgatga agcgatcagg tcggtccgtt tcgtttcacg
    21121 tgagccacat ctctttggac tggtgcacga cgcagcgcgg aagacctctc gcgaagcgat
    21181 ggtttctgcc acgattccga ttggggcggg acactgtccc gcccgccccg gcacgcctat
    21241 gaccagtggg agagtcacgg tgtacttcgc cgcattgctc gcgcgcaccg cagaagggtg
    21301 ggaagcgagc gacacagagc tcgatgacgt ggagactctg accgatttga tcgatctggc
    21361 tcgtggggcc gccaaggacg acgacacggt tctggccttc atcgagcacg aagacgcgtg
    21421 gttcggcgtc gtccgcgtgg acggcgagga cgacccgcac atctacgtat cggacgcggc
    21481 cgcggccgcc cgcacctcat acggctcgat gctcaccgac gagctgctcg gccgggaccc
    21541 cgacgacgac ctggacagcc tcgtcgacct ggacggcacc gaggacggcg agcccgacca
    21601 ggacgacgac gccgaccccg acgcccccgt cccggtgggc cccctcgggg acggcgacat
    21661 cctgaccgac ctgggcatgg aggagaagga actgaaggcc ctcgacgggg acgcgctcga
    21721 atcgatcgcg gacatgctgg ggtgcagcat ggagggcctg gaggcggtgc gctgaccgcc
    21781 gccacactgg tgacatgacc gacccgctga ccggcatcct gcccggaccc gaccccgacc
    21841 ccctgcgtga cccctggcgc gccccgatgc gcctcgcgct ggaggaggcc gtacgggcac
    21901 ccgagacggg agacgtcccg gtcggcgccg tcgtgctggg cccggacggc acggtgctcg
    21961 gccgcggccg caacgagcgc gaggcccacg gcgaccccac ggcccacgcc gaggtcctcg
    22021 ctctccgcgc cgcggcccgc cgcctcggcg gctggcggct caccgggtgc accctggtgg
    22081 tgaccctgga gccgtgcgcc atgtgcgcgg gcgccatcgt gctgtcccgg ctcgaccggg
    22141 tggtctacgg cgcggtcgac gagaaggcgg gcgccgtcgg ctccctctgg gacatcgtcc
    22201 gcgaccgccg cctcaaccac cgccccgagg tcatccacga cgtcctcccc gacgagtgcg
    22261 cggccccc
//
