LOCUS       NZ_CP040752            23385 bp    DNA     linear   CON 05-MAY-2024
DEFINITION  Streptomyces rectiverticillatus strain B15-08 chromosome, complete
            genome.
ACCESSION   NZ_CP040752
VERSION     NZ_CP040752.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces rectiverticillatus
  ORGANISM  Streptomyces rectiverticillatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7679243)
  AUTHORS   Park,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAY-2019) Laboratory of Bioorganic Chemistry, NIDDK,
            NIH, 9000 Rockville Pike, Bethesda, MD 20892, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: DEC-2018
            Assembly Method                   :: HGAP v. Dec-2018
            Assembly Name                     :: DDK_LBC_B15-08
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013394065.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 03:49:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,642
            CDSs (total)                      :: 6,543
            Genes (coding)                    :: 6,394
            CDSs (with protein)               :: 6,394
            Genes (RNA)                       :: 99
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 55 of 149
            Pseudo Genes (incomplete)         :: 125 of 149
            Pseudo Genes (internal stop)      :: 12 of 149
            Pseudo Genes (multiple problems)  :: 41 of 149
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:46:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7142809
            Orig. end                         :: 7166194
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040752.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from LBC, NIDDK.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23385
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="38"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23385
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23385
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13385]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13385
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            1260..1820
                     /locus_tag="FGW37_RS30895"
                     /old_locus_tag="FGW37_31195"
     CDS             1260..1820
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088718.1"
                     /locus_tag="FGW37_RS30895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_31195"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_179084085.1"
                     /transl_table=11
                     /translation="MALEHAILVSLLEKPGSGYELARRFERSIGYFWTATHQQIYRVLK
                     RMEGDGWIDVREVPQQGRPDKKEYSVAALGRAALSGWLHEPIEPESVRHDLAVKIRGAA
                     FDDPAALIREVERHHRAHSDRLAHYLAGEERDFTAPGAPGTPGDAGRELQHVVLRGGIA
                     YERMTIAWLDDVLATLHRLRREH"
     gene            1934..3655
                     /locus_tag="FGW37_RS30900"
                     /old_locus_tag="FGW37_31200"
     CDS             1934..3655
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088719.1"
                     /locus_tag="FGW37_RS30900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_31200"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_179084086.1"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.2e-18, bitscore:
                     66.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADQLLFNPRTYDPAHFDPETRRLLRATVDWFEERGKRKLIEDYR
                     SRTWLADFLAFSAKEGLFATFLTPSAAAGGHEDKRWDTARIAALNEIFGFYGLDYWYAW
                     QVTILGLGPVWQSDNAAARARAAELLAQGEVFAFGLSEKAHGADIYSTDMLLEPDGDGG
                     FRASGSKYYIGNGNAAGLVSVFGRRTDVEGPDGYVFFAADSRHEAYHLVKNVVDSSKYV
                     SEFRLDNYPVAAEDVLHTGRAAFDAALNTVNVGKFNLCTGAIGICEHAMYEAVTHAHNR
                     ILYGRPVTAFPHVRRELTDAYVRLVGMKLFSDRAVDYFRSAGPDDRRYLLFNPMTKMKV
                     TTEGEKVIDLMWDVIAAKGFEKDTYFAQAATEIRGLPKLEGTVHVNLALILKFMGNHLL
                     NPAEYAPVPTRLDAADDDFLFRQGPARGLGAIRFHDWRTAYDAYADVPNVGRFREQADA
                     LCEFVTTAAPDEEQSRDLDLLLAVGQLFALVVHGQLILEQARLTGLDRDVLDELFAVLV
                     RDFSAHAVELHGKDSATEEQQRWALGAVRRPVVDDARSARVWERVEALSGAYEMAP"
     gene            3755..5488
                     /locus_tag="FGW37_RS30905"
                     /old_locus_tag="FGW37_31205"
     CDS             3755..5488
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004953891.1"
                     /locus_tag="FGW37_RS30905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_31205"
                     /product="GAF domain-containing protein"
                     /protein_id="WP_179084087.1"
                     /transl_table=11
                     /translation="METTGGGSVRLPHLRLDELLGELQARLDTARGTWDRVHSLLEAVL
                     SVGRELDLEHVLRRIVEAAVVLVDARYGALGVIGQDGRTLSQFLTVGLTDEQIKAIGPF
                     PSGHGLLGELIRHPAPLRLPKISEHAASYGFPSGHPPMHSFVGVPISVRDQVFGNLYLT
                     EKRGGADFDAEDEAVLSTLAVAAGVAVDNARLYEESTRRERWLRASARVTTSLMSGSPR
                     QDVMAQIAELAKEITEAELATVSLPLDDGSALTVEVATGELADAIRGVVLPVEGSLVGV
                     VLSEREPVCSLSVDEDPRVSAVPKSLTGLGPAVAVPVKSGETVIGVLFLARGTGRPVFS
                     QEEIEPLLNFAGQAAMAMELAQRRADAEQLTLLEDRDRIARDLHDLAIQRLFATGMTLQ
                     SADRFIDHAEASERVQRAVNDLDETIKIIRATIFGLRSRETAPRHGLRTRVVQTVGGAA
                     ALLGFAPSLRMEGLLDTRVPRAVIDDAVAVLEEALTNVVRHARATSIGVCVVNDGRDLV
                     LTVTDDGVGMPGEGRRSGLRNLAERAERHGGQLLLSAPSGDGTVLTWRVPLPAEQPRTG
                     P"
     misc_feature    4232..4234
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5501..6262)
                     /locus_tag="FGW37_RS33620"
     CDS             complement(5501..6262)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010360499.1"
                     /locus_tag="FGW37_RS33620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_246430881.1"
                     /transl_table=11
                     /translation="MGQAEVFSQFSQDRPIRVFLLDDHEVVRRGVHDLLDAEDDIVVAG
                     EAGTVDHALARGPALRPDVAVLDVRLPDGDGITVCRELRSRMPGLACLMLTSFDDDDAL
                     LDAIMAGAAGYVLKQIKGSDLVSAVRTVASGQSMLDPATTTRLMTSLRGDGGDGGDAGP
                     GDERLAGLSPRERDILALIGDGLTNRQIGKSLFLSEKTVKNHISRLLAKLGVERRIQAA
                     VLATRAGGPAAEPGTPAGEPGDRREQSGRRA"
     misc_feature    complement(6336..6350)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 24.27"
                     /tool="antismash"
     misc_feature    6337..6351
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.9"
                     /tool="antismash"
     gene            complement(<7037..7375)
                     /locus_tag="FGW37_RS33625"
                     /pseudo=""
     CDS             complement(<7037..7375)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013714.4"
                     /locus_tag="FGW37_RS33625"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="FAD-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGPGPACCKEAPPAAAGGHGYGGYSTSPGLVIDVSRLGSVTADPR
                     SVRVGAGAQAVDVVDALAPYGLAVPGGTWATIAAAGFVQGGGIGYLTRSLGLACDRVTA
                     AQVVLADGR"
     gene            complement(7388..8263)
                     /locus_tag="FGW37_RS30915"
                     /old_locus_tag="FGW37_31215"
     CDS             complement(7388..8263)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093410.1"
                     /locus_tag="FGW37_RS30915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_31215"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_179084089.1"
                     /transl_table=11
                     /translation="MQRHEHAGPLALRAMQELATRAFPATGYRHIGDLTWSWCLALGRV
                     DACPTAVWTEGGRTLAWGWLDLPDSLMLQVDPDRAELAHDVLAWAEQAAPGPLHVEVAG
                     TESHLVKALEQRGYRRAVDGPFMACLDRALTGLPDVPPLPAGYVIRAQHDDTDVAGRAA
                     AHRAAFGSTRVTTERHARMRNAWPYRPELDLVVTSPAGDVVSYCQGWYDEVNATGAFEP
                     VGTHPDHRRLGLARAVCTAVLHAFARAGGRRAIVYSRGDADYPVPKRLYESMGFTMYTR
                     TRTFVSRPSD"
     misc_feature    8551..8566
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.5"
                     /tool="antismash"
     gene            9013..9543
                     /locus_tag="FGW37_RS30920"
                     /old_locus_tag="FGW37_31220"
     CDS             9013..9543
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016144.4"
                     /locus_tag="FGW37_RS30920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_31220"
                     /product="GrpB family protein"
                     /protein_id="WP_218650619.1"
                     /transl_table=11
                     /translation="MIEIVEYRDTWPALFGELGFRLRAGLGDVALRIDHIGSTAVPGLR
                     AKPVIDVQVSVEAFEPAAFRAPLEAMGFEFRAGDPDRTKRYFRETSGPRTHVHVRRAGS
                     FAEQFCLLLRDYLRDSPADAELYGARKALLAERYGMDRRAYTAAKSSVVWELVHRADVW
                     AQARGWQPGRSDA"
     gene            complement(<9741..>9876)
                     /locus_tag="FGW37_RS33630"
                     /pseudo=""
     CDS             complement(<9741..9876)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971352.1"
                     /locus_tag="FGW37_RS33630"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IclR family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVGPRGHGLRAIALPYLQDLSHATHQHVQLVVREGPGMRPRRVAV
                     "
     gene            complement(10001..11506)
                     /locus_tag="FGW37_RS30925"
                     /old_locus_tag="FGW37_31225"
     CDS             complement(10001..11506)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093192.1"
                     /locus_tag="FGW37_RS30925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_31225"
                     /product="DUF4334 domain-containing protein"
                     /protein_id="WP_246430655.1"
                     /sec_met_domain="T1TS (E-value: 3.2e-13, bitscore: 48.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTSLPVTHSPREMVSIADTCSVALQNMPRLENWLKELALPVDPA
                     LVPLMCLQTPFCTPWLSSETCYQVSRLMLWLMAIDNVLDAPGPAGATEARVRAWRRVLD
                     GRAGGGGDPVALALAEIAEALRRDGRPELAAVWRESMHQTLTGMTLENAAARAAAAGGG
                     LPRLTDYLLHGAWSIGVEQQVTALWALMDEPGLPLRLPVLRGALRQAATAIRLLNDLRG
                     HHRERSESKVDALAIGLGEQEAHQRAEAGIEGCRRALAPLTGAGYGSAVALERVVLWHA
                     RMYRHFDPVRPGQAAARPLPGGGPDATGTTRHAPFVHRPREAPPMGTEQEVPSEQQVRE
                     VQEVQEVLDVIASGADYDRARLMALFDRLEPVGTGLLIGTWRGGAFESDSENAEQLAKM
                     RWYGKRFVDADHVEPLLCRDENGEVYSYEEMGLATLREVVHRGKQSTAMVYDQLPIIDH
                     FRRLTDDVLLGVMDKKGDPADFYFHLTRVPSPTRPADEPPATR"
     misc_feature    complement(11432..11434)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    11644..11659
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.69"
                     /tool="antismash"
     gene            11718..13385
                     /locus_tag="FGW37_RS30930"
                     /old_locus_tag="FGW37_31230"
     CDS             11718..13385
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012647.4"
                     /locus_tag="FGW37_RS30930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_31230"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_179084091.1"
                     /sec_met_domain="T2TS (E-value: 3.4e-28, bitscore: 97.0,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRSLTLATRHALATQRDNGSWLATPSPRITETALGTLALSLSRS
                     LHPGAGRAAERGLAWLTGSAAPQNHHPVAHAVESALLSLALDTGGPVDVSHPAFTDEAL
                     AARARLVQAVALHRGRAARGGTAPETLRKELAAAVAAPGRLKRWTRVELWSAHALVELH
                     IGDRNAARRAALTIAEEQSPAGDFSGSPVATALAALALQAAAPGSAAAHRCTEHLIAGQ
                     LPDGTWRFSTSDVWDTALTVRSFRGNPAFDRHGLPAAVAFLVAAQNPDGGWPYRLGVES
                     DNDTTAAALIALAGVDDGATAGTVRAGLRHLARQQTSDGLWRTWQSAGDPPVDDVVAHV
                     VTALDRHRGHHHVPLAAARTWLTGRFGERGRWQAGWYRGLPYATAEVLPALGTTAHHEK
                     GTPAHHNKGTTALHDKGTTAHHQSAAVHSGGATPHPPGHPAARALAATRNPDGGWPVEA
                     GGPSTPAATGLALAALERGGLVGGEHDETCWAPGLGHLLETQRGDGTWPGVPLMYGPRP
                     LLTHFPTHTHAFVVDGLFAGQRRLRAAGGDAAAAHKVV"
     gene            13387..14757
                     /locus_tag="FGW37_RS30935"
                     /old_locus_tag="FGW37_31235"
     CDS             13387..14757
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543110.1"
                     /locus_tag="FGW37_RS30935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_31235"
                     /product="cytochrome P450"
                     /protein_id="WP_179084092.1"
                     /sec_met_domain="p450 (E-value: 1.5e-73, bitscore: 246.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTSMAPKRSSVEVPTAPGRLPLAGHAPWLHRDALRFVRELRRHG
                     PVTKIYIGPRPVHVLSSGELIRELLTVRARSFDKGAMFDALRVPLGDGLITAAGDRHLR
                     HRRMMQPAFHHERIARCTRVMTDCSGARSAAWEPGTTRDLMPDIHRLTLDILLGTLFAH
                     PQDPGLRPAVKDWLAVKYHSMRLALSPLHAWAERVPLLPGWRPPDPGPLRRLVAVLRRI
                     VETYRADGRDHGDLLSMLLLAEGPDGALTDAEVTDELITLFLAGTGTVSAALAWALYEI
                     SRRPEVQRRLHDELDTVLAGRPPGFEDLPALIHTRQILTETLRLRPPSWLLMRRAVRPV
                     RLGGVHLSPGEEVFFSPYALHRDPHLYEDPERFDPERWPRDSAAKAPRHLYLPFGAGSR
                     LCIGEDFAWAELTLALAAFTAHRRIAPADAAPPVRPLVGTVLRPDRLLLTGHPRRAL"
     gene            14800..15585
                     /locus_tag="FGW37_RS30940"
                     /old_locus_tag="FGW37_31240"
     CDS             14800..15585
                     /NRPS_PKS="Domain: PKS_KR (20-185). E-value: 1.5e-10.
                     Score: 33.2. Matches aSDomain:
                     nrpspksdomains_FGW37_RS30940_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174125.1"
                     /locus_tag="FGW37_RS30940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_31240"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_179084093.1"
                     /sec_met_domain="adh_short (E-value: 5.4e-34, bitscore:
                     116.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVLAQTPDNGAQLGRLHDRVALVTGGGSGIGAVCAGRLAEEGAV
                     VVVADLDVDGATRVAEEITKAGGTALPRRIDVTDPDSVARVVSEAAGLHGGLRIAVNSA
                     GTNGPLVPLAQLAPADFDTVMRVNLYGVFHAMRCQLPAMAATGGAIVNIASIAAHSGFR
                     GHAAYAAAKQGVLALTRTAAREYAGQGVRVLSVSPGLVDTPMAAALPPGATADLLASVP
                     LRRIAQPSEIAALVAFLVSDDASYLTGSDHVIDGGYLAK"
     aSDomain        14860..15354
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FGW37_RS30940_PKS_KR.1"
                     /evalue="1.50E-10"
                     /label="FGW37_RS30940_PKS_KR.1"
                     /locus_tag="FGW37_RS30940"
                     /protein_end="185"
                     /protein_start="20"
                     /score="33.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VALVTGGGSGIGAVCAGRLAEEGAVVVVADLDVDGATRVAEEITK
                     AGGTALPRRIDVTDPDSVARVVSEAAGLHGGLRIAVNSAGTNGPLVPLAQLAPADFDTV
                     MRVNLYGVFHAMRCQLPAMAATGGAIVNIASIAAHSGFRGHAAYAAAKQGVLALTRTAA
                     RE"
     CDS_motif       14866..14943
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FGW37_RS30940_0001"
                     /evalue="4.40E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="FGW37_RS30940"
                     /protein_end="48"
                     /protein_start="22"
                     /score="12.9"
                     /tool="antismash"
                     /translation="LVTGGGSGIGAVCAGRLAEEGAVVVV"
     misc_feature    complement(16148..16161)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 17.89"
                     /tool="antismash"
     gene            16251..16823
                     /locus_tag="FGW37_RS30945"
                     /old_locus_tag="FGW37_31245"
     CDS             16251..16823
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669736.1"
                     /locus_tag="FGW37_RS30945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_31245"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_179084094.1"
                     /transl_table=11
                     /translation="MTTADGTAYVFRTARPEDTDAIEALDGSFTTGTVFRVEVADDGFT
                     LREVPVDPPLTKVFPEDEPDGGAEDGDDGEDPGSRTFLAITAGGGLAGFVAVSYSPWNR
                     RLTVEDIEVAPDHRGRGVGRALMECAGKFARERGAGHIWLEVTNVNAPAIHAYRRMGFA
                     FCGLDTVLYDGTASEGEQALYMSKPCP"
     gene            complement(16799..17179)
                     /locus_tag="FGW37_RS33635"
     CDS             complement(16799..17179)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FGW37_RS33635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_246430656.1"
                     /transl_table=11
                     /translation="MLGAPPEAERMAYLLHFADGLGVPVERTLLGAAGAALRAVGAGSR
                     RTGGEWAVPLTVWRSAPFPTWYADRRAAGDRLLDARVEWYAPHAGPDGGAAWLLTVTIA
                     PGDGSAPAVGRLLSAQGQGLLI"
     gene            complement(17479..17844)
                     /locus_tag="FGW37_RS30955"
     CDS             complement(17479..17844)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FGW37_RS30955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_179079118.1"
                     /transl_table=11
                     /translation="MHDRDQGRPDPVGEALARAEAAYAEAGTRLPPEYEAFVRLVQNLS
                     PRTLADEGAAAEWLDLFEVAALTGTSAAHRPQPPVRNRLADYARITTPLLVVGFADDVL
                     DFLATLSTTDPGGPRVR"
     gene            17839..17997
                     /locus_tag="FGW37_RS30960"
     CDS             17839..17997
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FGW37_RS30960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_179079119.1"
                     /transl_table=11
                     /translation="MHRLDSVREADRIAVMDRGRIVELGSHEELLAAEGAYAALWHAWD
                     SARGRGA"
     gene            18058..18240
                     /locus_tag="FGW37_RS30965"
                     /old_locus_tag="FGW37_31260"
     CDS             18058..18240
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FGW37_RS30965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FGW37_31260"
                     /product="hypothetical protein"
                     /protein_id="WP_179084095.1"
                     /transl_table=11
                     /translation="MVTGDPQGAVAIANRALDEVGRLRSRRAAEDLRELFRYSSHHSKQ
                     PDVTELRRRITTAPA"
     gene            complement(18880..19257)
                     /locus_tag="FGW37_RS30970"
                     /old_locus_tag="FGW37_31265"
     CDS             complement(18880..19257)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020120519.1"
                     /locus_tag="FGW37_RS30970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_31265"
                     /product="DUF2568 domain-containing protein"
                     /protein_id="WP_246430657.1"
                     /transl_table=11
                     /translation="MSGYGFHPLTLGVRFVLELVALMCFGLWAWVTAPAPLQYVFVVAV
                     PLVAAVLWGVFATPGDASRSGGTVIATPGLLRLLLELAVFFGSAAALYATDFRTPAVML
                     AGVLVMHHLLSWDRVLWLLRH"
     gene            complement(19383..20402)
                     /locus_tag="FGW37_RS30975"
                     /old_locus_tag="FGW37_31270"
     CDS             complement(19383..20402)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FGW37_RS30975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FGW37_31270"
                     /product="YcxB family protein"
                     /protein_id="WP_179084096.1"
                     /transl_table=11
                     /translation="MASFKYRRLFVACIVTGLATLFVSAGQAGGAESVAHNHPVSHEIS
                     IFALRQQGPEDNVHPEQHGEIRPLINGQDVIEDVYPEGTTSWWQGIPLAATEAGRKVML
                     TAAECSTTCCGSVWVTIRREGSHMLWTDWENSGDSGKLPPEYRFDADQYDTELARATAA
                     FLPQNTGRGKSVEFVYQPTAADFEEALRARARRTAAGRTQALLGPLMAAAGVAAFAVLR
                     DIALPVWITALVLSVAAASWGTVRGLRTMARRMFSIVEPYGQCRVVADDRGMASTGERV
                     SFTHDWTVFREYLETPGLFVLLGGERAAGVSVVPKRGAQGPADVDQFRVVLDRNLKRI"
     misc_feature    20738..20752
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.87"
                     /tool="antismash"
     misc_feature    20807..20821
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 20.54"
                     /tool="antismash"
     misc_feature    20889..20906
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            21043..21417
                     /locus_tag="FGW37_RS30980"
                     /old_locus_tag="FGW37_31275"
     CDS             21043..21417
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FGW37_RS30980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FGW37_31275"
                     /product="hypothetical protein"
                     /protein_id="WP_179084097.1"
                     /transl_table=11
                     /translation="MSRTLSRIVTSAAAVGCLAAAMVVGPTSAQAAPPCPATDAVCQYS
                     GVFFTGSTDIDRRPLTGTCTQVDFPGANNGTALSVRNNTSHVLVEFLDENCTVPAGASV
                     QPFGNQPAGSYSSYLLDVIG"
     misc_feature    complement(21696..21710)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.23"
                     /tool="antismash"
     gene            21736..22565
                     /locus_tag="FGW37_RS30985"
                     /old_locus_tag="FGW37_31280"
     CDS             join(21736..22080,22083..22565)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011026834.1"
                     /locus_tag="FGW37_RS30985"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="FGW37_31280"
                     /product="IS5 family transposase"
                     /protein_id="WP_246430883.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MIWGCGVARSKPWEVDDELWAVIERLLPKVERRPLHPGRRRHPDR
                     LVFQGILFVLHTGIAWEHLPQELGFGSGMTCWRRLAEWTEAGVWPRLHGVLLAKLRSAN
                     ALDFSRAAVDGPHTGVKGGSKTGRSPVDRGRTGSKYHLITDATGIPLAATLTGGNRHDV
                     TQLIPLLQAVPPVRGKRGRPRHRPDVVLGDRGYDHDKYRRLVRDLGVKPLIARRGTEHG
                     SGLGAQRWVVERAFARLHWFRRLRVRWEIRDDIHEAFLTLGCALICWRRLNSR"
     gene            complement(22613..23353)
                     /locus_tag="FGW37_RS30990"
                     /old_locus_tag="FGW37_31285"
     CDS             complement(22613..23353)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823099.1"
                     /locus_tag="FGW37_RS30990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_31285"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_179084098.1"
                     /transl_table=11
                     /translation="MTSSELWTRATADRYDAEETETSSAAVLGPALAFLAELAGDGRAL
                     EFAIGTGRVGVPLRERGVPVVGIELSEHMAAVLRRKIDEDTLPVVIGDMATTVVPGEFT
                     LVYLVYNTITNLLTQDEQVECFRNAARHLEPGGRFVIELGVPPLRFLPPGQVAVPFDVS
                     EQHLGFDTFDLVEQILVSHHFTRDGDDGRYRRDNSRHRYAWPAELDLMARIAGLEMERR
                     VADWDGAPFTQDSAKHISVWRKPT"
ORIGIN
        1 gcggaaggtg acgctgttct gcggcagcgg cacggcgggg gcccacgagg aggtgatgcg
       61 cttcgcggag cgggtcaagg ctcccgtcgg gcacgcgctg cgcggcaagg agtggatcca
      121 gtacgacaac ccctacgacg tcggcatgag cggcctgctc ggctacgggg ccgcctacga
      181 ggccacccac gagtgcgacc tgctgctcct gctgggcacc gacttcccgt acaacgcctt
      241 cctgccggac gacgtgaaga tcgcgcaggt ggacgtccgg cccgagcacc tgggccggcg
      301 gtccgcgctc gacctcgcgg tgtggggcga cgtccgcgag acgctgcgct gcctgacgcc
      361 gcgcgtgcag gtcaagagca gccggaagtt cctcgacaag atgctcgcga agcacgccga
      421 cgccctcgaa ggcgtcgtga aggcgtacac gcggaaggtg gagaagcaca ccccgatcca
      481 cccggagtac gtggcctccg tcctggacga ggaagccgcc gacgacgcgg tcttcaccat
      541 cgataccggg atgaacaacg tctgggcggc ccgctacctc accccgaacg gccgccgccg
      601 cgtcatcggc tccttcaccc acgggtcgat ggcgaacgcc ctgccccagg cgatcggggc
      661 gcagctcctg gaccggggcc ggcaggtcgt ctcgatgtcc ggcgacggcg ggttctccat
      721 gctgatgggc gacttcctga cgctggtgca gtacggcctg cccgtgaagg tggtcctgtt
      781 caacaactcg tcgctcggca tggtcgagct ggagatgatg gtgggcggcc tgccgtcgta
      841 cggcacggcc aaccacaacc ccgacttcgc cgccatcgcc ggcgcggccg gtgcctacgg
      901 cgtgcgggtg gagaagccga agcacgtgcg gagtgccctg cgggacgcgt tccggcacaa
      961 gggcccggcg ctggtggaca tcgtgaccga ccccaacgcc ctgtcgatcc cgccgaagat
     1021 caccgcggac atggtcagcg gcttcgccct gtcggcggga cggatggtcc tggagggtgg
     1081 cgtgggccgg atggtccgga tggcgcgctc gaatctgcgc aacatcccac gcccctgaga
     1141 gctgagggct cctcgcccgt gagggctctt cgtcccctga ggcgcggctg cgagtgagcc
     1201 gcgtctcacc cgggcggtgg tgcttgtcta tgaaacgagt tgcatagcag gatccgggta
     1261 tggcgctcga gcacgcgatc ctcgtctccc tgctggagaa gccgggctcc ggctacgagc
     1321 tggcccggcg cttcgagcgg tccatcggct acttctggac cgccacccac cagcagatct
     1381 accgcgtcct caagcggatg gagggcgacg gctggatcga cgtgcgcgag gtgccgcagc
     1441 agggccggcc ggacaagaag gagtactccg tcgccgccct cgggcgcgcc gccctctccg
     1501 gctggctcca cgagccgatc gaacccgaga gcgtccggca cgacctcgcc gtgaagatcc
     1561 gcggcgcggc cttcgacgac ccggccgcgc tgatccgcga agtcgagcgg caccaccggg
     1621 cgcactccga ccggctcgcg cactacctcg cgggggagga gcgcgacttc accgcacccg
     1681 gggcgcccgg cacacccggc gacgccgggc gggagctcca gcacgtcgtc ctgcgcggcg
     1741 gcatcgccta cgagcggatg acgatcgcct ggctcgacga cgtcctcgcc acgctccacc
     1801 ggctccgccg cgagcactga acccgcgttc caccgcgacc cgccgcctcc acctttgcct
     1861 ccaccttcac ctccgcctcc accatcaccg tccaccgcca ccttcgaccg tcaagccgga
     1921 aaggcgaacc tccatggccg accagctgct cttcaacccg cgcacctacg accccgcgca
     1981 cttcgacccc gagacccgca ggctgctgcg cgccaccgtc gactggttcg aggagcgcgg
     2041 caagcgcaag ctgatcgagg actaccgctc ccgcacctgg ctggccgact tcctcgcctt
     2101 ctcggcgaag gagggcctgt tcgccacctt cctcacaccg tccgccgccg ccggcgggca
     2161 cgaggacaag cgctgggaca ccgcccgcat agccgccctc aacgagatct tcggcttcta
     2221 cgggctcgac tactggtacg cgtggcaggt caccatcctc ggcctcggcc cggtctggca
     2281 gagcgacaac gccgccgccc gcgcccgcgc cgccgaactc ctcgcccagg gcgaggtgtt
     2341 cgccttcggc ctgtccgaga aggcccacgg cgccgacatc tactccaccg acatgctcct
     2401 ggagccggac ggcgacggcg gcttccgggc gagcggctcc aagtactaca tcggcaacgg
     2461 caacgccgcc ggcctcgtct ccgtcttcgg ccgccgcacc gacgtcgagg gccccgacgg
     2521 ctacgtcttc ttcgccgccg acagccgtca cgaggcgtac cacctcgtca agaacgtcgt
     2581 cgactcgtcg aagtacgtca gcgagttccg cctcgataac tacccggtcg cggccgagga
     2641 cgtcctgcac accggccgcg ccgccttcga cgccgccctc aacaccgtca acgtcggcaa
     2701 gttcaacctc tgcaccggcg cgatcggcat ctgcgagcac gcgatgtacg aggccgtcac
     2761 gcacgcgcac aaccgcatcc tctacgggcg ccccgtcacc gcattcccgc acgtgcgccg
     2821 cgagctgacc gacgcctacg tccgcctcgt cgggatgaag ctgttcagcg accgcgccgt
     2881 cgactacttc cgctccgccg gccccgacga ccgccgctac ctgctcttca accccatgac
     2941 gaagatgaag gtgaccacgg agggcgagaa ggtcatcgac ctgatgtggg acgtcatcgc
     3001 ggccaagggc ttcgagaagg acacctactt cgcccaggcc gccacggaga tccggggcct
     3061 gccgaagctg gagggcaccg tccacgtcaa cctcgcgctg atcctgaagt tcatgggcaa
     3121 ccacctgctc aacccggccg agtacgcgcc cgtgccgacc cgcctcgacg cggccgacga
     3181 cgacttcctc ttccgccagg gcccggcccg cggcctcggc gccatccgct tccacgactg
     3241 gcgcaccgcc tacgacgcct acgccgacgt acccaacgtc ggccgcttcc gggagcaggc
     3301 ggacgcgctg tgcgagttcg tcaccaccgc cgcgcccgac gaggagcaga gccgcgacct
     3361 cgacctcctc ctcgccgtcg gccagctctt cgcgctcgtc gtgcacggcc agctgatcct
     3421 ggagcaggcg cgcctgaccg gcctcgaccg ggacgtgctc gacgagctgt tcgccgtcct
     3481 cgtccgcgac ttctccgcgc acgccgtcga actgcacggc aaggactccg ccaccgagga
     3541 gcagcagcgc tgggccctcg gcgcggtccg ccgccccgtc gtcgacgacg cccgctcggc
     3601 ccgcgtctgg gagcgcgtcg aggcgctgtc aggcgcgtac gagatggcgc cgtaacccac
     3661 ttccggccgg ggcgggtgca gccgtttctg ccccgccccg ggcccgatac ggtggtccgg
     3721 cgagacacac gtcgtccgtt cgtgaggaga cgcgttggag accaccgggg gtggttcggt
     3781 gcggctgccg cacctcagac tggacgagct gctgggggag ctccaggcgc ggctcgacac
     3841 cgcacgcggt acgtgggacc gggtgcacag cctgctggag gcagtgctgt cggtggggcg
     3901 cgaactggat ctggagcacg tgctgcgccg gatcgtcgag gcggcggtgg tgctggtgga
     3961 cgcccggtac ggggcgctgg gggtcatcgg ccaggacggg cgcacgctct cgcagttcct
     4021 cacggtcggg ctgacggacg agcagatcaa ggccatcggg ccgttcccct cggggcacgg
     4081 gctgctcggg gagctgatcc ggcaccccgc cccgctgcgg ctgccgaaga tctccgagca
     4141 cgccgcctcg tacggcttcc cgtccggcca tccgccgatg cacagcttcg tgggcgtccc
     4201 catcagcgtc cgcgaccagg tgttcgggaa cttatacctg accgagaagc gcggcggggc
     4261 ggacttcgac gccgaggacg aggcggtgct ctccacgctc gccgtcgccg cgggcgtcgc
     4321 cgtcgacaac gcccgcctgt acgaggagtc cacgcggcgc gaacgctggc tgcgggcgag
     4381 cgcccgggtg acgaccagtc tgatgtccgg cagcccgcgg caggacgtga tggcccagat
     4441 cgccgagctg gccaaggaga tcaccgaggc cgagctggcg acggtctcgc tgccgctgga
     4501 cgacgggtcc gcgctgaccg tcgaggtcgc cacgggcgaa ctggccgatg ccatccgcgg
     4561 tgtcgtcctc cccgtcgaag ggagcctggt cggcgtcgtg ctctccgagc gcgagccggt
     4621 ctgcagcctc agcgtcgacg aggacccgcg ggtctccgcg gtgcccaagt cgctgacggg
     4681 gctgggaccg gcggtggcgg tgccggtcaa gtccggcgag acggtgatcg gcgtgctgtt
     4741 cctggcccgg ggcacggggc ggccggtgtt ctcgcaggag gagatcgagc ccctgctgaa
     4801 cttcgccggg caggcggcca tggccatgga actggcgcag cgccgggcgg acgccgaaca
     4861 gctcacgctg ctggaggacc gcgaccggat cgcccgcgac ctgcacgacc tggcgatcca
     4921 gcggctgttc gccacgggca tgacgctgca gagcgcggac cgcttcatcg accacgcgga
     4981 ggcgtcggag cgcgtgcagc gggccgtgaa cgacctcgac gagaccatca agatcatcag
     5041 ggcgacgatc ttcggtctgc ggtcccggga gaccgcgccc cggcacgggc tgcgcacccg
     5101 tgtcgtgcag accgtcggcg gcgccgccgc gctcctcggc ttcgcgccga gcctgcgcat
     5161 ggagggcctg ctggacaccc gggtgccgcg cgccgtcatc gacgacgcgg tggcggtcct
     5221 ggaagaggcc ctgacgaacg tcgtccggca cgcccgcgcc acgtccatcg gcgtctgcgt
     5281 ggtcaacgac ggccgggacc tggtgctcac cgtcaccgac gacggcgtcg gcatgcccgg
     5341 cgaagggcgc cgcagcgggt tgcgcaacct cgccgaacgc gcggaacggc acggcgggca
     5401 gctgctgctc tccgccccct ccggcgacgg cacggtactg acctggcgcg ttcccctccc
     5461 ggcggagcag ccgcggaccg gtccttgaac ggcttgcggc tcaggcccgg cggccggact
     5521 gctcccggcg gtccccgggt tcgcccgctg gcgtgcccgg ctcggcggcg ggcccgccgg
     5581 cccgggtggc gaggacggcc gcctggatgc ggcgctcgac gccgagtttg gcgagcagcc
     5641 gcgagatgtg gttcttgacc gtcttctcgg acaggaacag actcttgccg atctgacggt
     5701 tggtgagccc gtcaccgatc agcgcgagga tgtcgcgctc gcgaggggag aggccggcga
     5761 gccgctcgtc gccgggtccg gcgtcccctc cgtcccctcc gtccccgcgc aggctcgtca
     5821 tcaggcgcgt ggtcgtggcc gggtcgagca tggactggcc ggaggcgacg gtgcggacgg
     5881 cggagacgag gtcggacccc ttgatctgct tgaggacgta cccggcggcc ccggccatga
     5941 tcgcgtccag gagggcatcg tcgtcgtcga acgaggtcag catcaggcag gcgagccccg
     6001 gcatccgcga gcgcagctcc cggcagacgg tgatgccgtc gccgtccggc agccgcacgt
     6061 ccaggacggc gacgtcgggg cggagggcgg gcccccgggc gagggcgtgg tcgacggttc
     6121 ccgcttcgcc ggcgaccacg atgtcgtcct cggcgtccag caggtcgtgg acaccccgcc
     6181 ggaccacctc gtggtcgtcc aggaggaaga cccggatcgg cctgtcctgg gagaactggg
     6241 agaacacctc tgcctggccc acaaccggct cccgtcgacg gtcggcgcac cgctgcgctg
     6301 caccgatcat gatctgccgg gagcggcgtc caccatgggc cgaacggccc tgagagggat
     6361 cagccgcccc tgggtgcggg cgccgggtcg atgccctgcg ggaagcggaa ggccccgtgg
     6421 cggtcgtact cggccttgac ggaggagagg cgggcgtagt tctcggcgta gtacgcgtgg
     6481 cgccagtcgc ggagggacgg gtcgatgaag ttctggtagg tctcgccgtt ggagtgggga
     6541 tcgacggcgt ggaaaccggc gtcggccctg ggagccggcc ctcgggcgtg ctgccggtgc
     6601 ggtggcactg cgcggccgtg agggtgccgc atttgaaggt ctccatcatg aaggaccggt
     6661 acggagtccg ctcgacggag cggtccgccg gcggaccgca gtaggagacc aggcgagcga
     6721 cttcggagtt gagttcggca ccggtgccgg tggacagcag ggtcactccc gcgaggggcg
     6781 tcccgcccgg agccgcgtcg accaggacgg ccacggcggc gccgccgatg gtccgcgggg
     6841 cctcgaccag ccagtgggcg aagccgtcca tcatgtcgac ggcgtggtcc caggtccagg
     6901 acagccgcgc cgtccgtacc gggccgacgg ccgcgggggt catggcgtac gaggtgacga
     6961 cgccgaaatt gccgccgccg ccaccccgca acgcccagtg cagatcgggg tgttcctccg
     7021 gggaggcggt gacgacccgg ccgtccgcga ggaccacctg cgccgcggtg acccggtcgc
     7081 aggccaggcc gagggagcgc gtgagatagc cgatgccgcc gccctggacg aacccggccg
     7141 cggcgatcgt cgcccacgtg ccgccgggca cggccagccc gtacggggcg agcgcatcga
     7201 cgacgtcgac cgcctgcgcg cccgcgccca cccgcacgct ccgggggtcc gccgtcaccg
     7261 agccgagccg cgagacgtcg atgaccaggc ccgggctggt ggagtacccg ccgtagccgt
     7321 ggccgcctgc ggccgcaggc ggcgcttcct tacagcaggc gggccccggt cccatcggca
     7381 gaacacctca gtccgacggc ctgctgacga aggtgcgggt gcgggtgtac atggtgaagc
     7441 ccatggattc gtagagccgc ttggggacgg ggtagtcggc gtcgcctcgc gagtagacga
     7501 tggcacgccg gccaccggcg cgggcgaagg cgtgcagcac cgcggtgcag acggcccggg
     7561 ccaggcccag gcggcggtgg tcgggatggg taccgaccgg ttcgaacgcg ccggttgcgt
     7621 tgacctcgtc gtaccagccc tggcagtagg acacgacgtc tccggcgggc gatgtcacca
     7681 cgaggtcgag ttcggggcga tagggccagg cgttcctcat acgggcatgg cgttcggtgg
     7741 tgacccgggt cgatccgaag gcggcacggt gtgcggcggc ccggccggcc acgtcggtgt
     7801 cgtcgtgctg agcccggatc acatagccgg ccggcagagg tggaacgtcc ggcagtccgg
     7861 tgagggcacg gtcgaggcat gccatgaacg ggccgtcgac agctcgcctg tatccgcgct
     7921 gttccagcgc tttgaccagg tgtgattcgg tgccggccac ctcgacgtgc agcgggccgg
     7981 gtgccgcttg ttcagcccag gcgagcacgt cgtgcgccag ttccgcgcgg tccgggtcga
     8041 cttggagcat caggctgtcc ggtagatcca gccaccccca ggccagcgtt cgcccgcctt
     8101 cggtccagac tgccgtcggg catgcgtcga cgcggccgag agccaggcac cagctccagg
     8161 tgaggtcacc tatgtgccgg tagccggtcg ccgggaaggc tcgggtggcc agttcctgca
     8221 tggcgcgcag cgccaagggt ccggcgtgtt catggcgttg catgggcgcc atgctgccga
     8281 acggctttcg atcgagcaac ggaatatggc ataggcctcc tcgacgcggc gacctgctcg
     8341 tttccctgcc cgggccgaac ggtgcggcgg gcgtcccggc gcagccggga catccggcga
     8401 cggcggaccc cgacgtcacc gccgcgggcc cggattcccg gcgcgcgtcg cggtggatgc
     8461 cttgtcgccg ggccggcatc tcatcggcgc acctgaaggt cgtggagtgc ggcaacacct
     8521 acgccgcggc cgtccccatg gcgccctccc ctcaccttct cttcacttga ccggtcggac
     8581 gcgcaccgca cggtccatgc tctcccgggg gctttccctc ctgaactgct ttcctgagct
     8641 tcctcctgcc gtcacccggc accggcccgg cgcagggcgg ccggcgccct gcgacaccgc
     8701 ccgggacacc cacgtgctgg tcaggccgga cggcgtcagt cgcggcccgg ccccggaggg
     8761 cccagacggg acgctggtat ccggaaaagc tgaacgagcc ggacggcccc ctcacactcg
     8821 cttgtcgggg gcaggggtgc gtggaggctc cgtggatcct gacgatgtga tggtggccga
     8881 cccgacgggg cccgagaagg cgggcggtgt tcccccacat ggaacggcaa tccgcggggc
     8941 ccgtcgtatc gttccgcctg acggaacgcc gggcctccga agcggtccgg tggcgccgtt
     9001 agggtgcggt gcgtgatcga gatcgtggag taccgcgaca cctggccggc cctcttcgga
     9061 gagctgggct tccgcttgcg cgccgggctc ggggacgtcg cactgcgcat cgaccacatc
     9121 ggctcgaccg cggtaccggg tctgagggcg aagcccgtga tcgacgtcca ggtgtccgtc
     9181 gaggcgttcg aacccgccgc cttccgcgca ccgctggagg cgatggggtt cgagttccga
     9241 gccggcgacc ccgaccggac gaaacggtac ttccgcgaga cgtccggccc ccgcacccat
     9301 gtgcacgtcc ggcgggcggg cagcttcgcg gagcagttct gcctgctgct gcgcgactat
     9361 ctccgggaca gtcccgcgga cgcggagctg tacggagcgc gaaaggcctt gctggccgag
     9421 cggtacggca tggaccggcg tgcctacacc gcggcgaagt cctcggtggt gtgggaactg
     9481 gtgcaccggg ccgacgtgtg ggcgcaggca cgcggctggc agcccggtcg gagcgacgcc
     9541 tgaccgccgc cgtcagccga gagcaccagg gcgcagagga cgggcagccg ggcccgcgct
     9601 ccgtcggcgg cggcaccgct cagggccggc gcagtcgggg ggcggtacag tccggcacag
     9661 cggaaggaag gccggcggca ccatcgggtg cacggtccga gcgtgcccca gcggaacata
     9721 acgggctggg cgtcatgcgc ggacagccac tcggcgagga cgcattcccg ggccctcgcg
     9781 cacgacgagt tgcacgtgct ggtgggtggc gtgcgagagg tcttgcaggt agggaagggc
     9841 gatggcgcgc aggccgtggc cgcgtggtcc cacggtgcac cggtgccctc ggggcggcga
     9901 tgcgggcggc ggggtgtgtg ccggctgccc cttgcgcacc gcagccatcc gctccggcga
     9961 gtggttcccc ggcccgcagc ccggggtcac gggctcgggg tcaccgtgtt gcgggcggct
    10021 catcggccgg ccgtgtgggt gacggcaccc gggtgaggtg gaagtagaag tccgccgggt
    10081 cgcccttctt gtccatcacg cccagcagga cgtcgtcggt gagccggcgg aagtggtcga
    10141 tgatgggcag ctggtcgtag accatcgccg tggactgctt gccgcggtgg acgacctccc
    10201 gcagtgtcgc caggcccatc tcctcgtacg agtagacctc cccgttctcg tcccggcaca
    10261 gcagcggctc cacgtgatcg gcgtcgacga accgcttgcc gtaccaccgc atcttcgcca
    10321 gctgctcggc gttctcactg tcgctctcga acgcgccgcc ccgccaggtg ccgatgagaa
    10381 ggccggtgcc caccggttcc agccggtcga agagggccat cagcctggcg cggtcgtaat
    10441 ccgctccgga cgcgatgacg tccaggactt cctgaacttc ctgaacttcc cggacctgct
    10501 gctcgctcgg gacttcctgt tccgtaccca tgggcggggc ctccctcggc cggtgaacga
    10561 acggagcgtg gcgcgtggtc ccggtggcgt ccggtccgcc gccgggcagg ggacgggcag
    10621 ccgcctgtcc gggccgtacg gggtcgaagt ggcggtacat ccgtgcatgc cagagcacca
    10681 cccgctccag tgccaccgct gaaccgtacc cggccccggt cagcggtgcc agggcccgtc
    10741 ggcagccctc gatcccggcc tccgcgcgct ggtgcgcctc ctgttcgccc aggccgatgg
    10801 cgagggcgtc gaccttgctt tcggaccgtt cccggtggtg cccgcggagg tcgttgagca
    10861 ggcggatcgc ggtcgcggcc tggcggagtg cgccgcgcag cacgggcagc cggaggggca
    10921 gccccggctc gtccatgagc gcccacaggg cggtgacctg ctgctcgacg ccgatgctcc
    10981 aggcgccgtg cagcaggtag tcggtcaggc ggggcaggcc gcccccggcc gccgccgccc
    11041 gggccgccgc gttctcgagg gtcatgccgg tgagcgtctg atgcatgctc tcccgccaga
    11101 cggcggcgag ctcggggcgg ccgtcgcgcc gcagggcctc cgcgatctcc gccagagcga
    11161 gcgccacggg gtcgccgccc cctcctgcac gcccgtcgag gacccgtcgc caggcacgca
    11221 cccgggcctc cgtagcgcct gccgggcccg gcgcgtccag cacgttgtcg atcgccatca
    11281 gccagagcat gagccgggac acctggtagc aggtctccga ggacagccat ggtgtgcaga
    11341 agggcgtctg aagacacatc agggggacga gtgcggggtc cacggggagt gcgagctctt
    11401 tgagccagtt ttcgagccgc ggcatgttct gtaacgcgac ggagcatgtg tccgctatcg
    11461 agaccatctc ccgtggggag tgggtgaccg gtagtgaagt gtccacgctg tcaggctact
    11521 tcgggtcctc gtacgcgatc cggcgccccc ggctcccgca cgggcccacc aggacctcta
    11581 tccatgcccc cggcagcatc cggagcgcca gaggcagtac gagtagcagc agcacgagaa
    11641 gcagaggaca gatgtcaaca ggacgtgcgt taccccgcgc accgcacgcg tgctcatcgc
    11701 ctgtgctcgc ggcacaggtg aatcgttccc tcaccctcgc cacccggcac gccctcgcca
    11761 cccagcggga caacggctct tggctcgcca ccccctctcc ccgcatcacc gaaaccgcgc
    11821 tcggcacgct ggccctctcc ctctcccgct cactgcatcc gggagccggg cgggccgccg
    11881 agcggggcct ggcatggctc accggcagcg ccgctcccca gaaccaccat ccggtggcgc
    11941 acgccgtgga gtccgcgctg ctgtccctgg ccctggacac cggtggtccc gtcgacgtca
    12001 gccaccccgc gttcaccgac gaggcgttgg ccgcccgtgc ccgcctggtc caggccgtcg
    12061 ccctgcacag gggacgtgcg gcccgcggcg gcaccgcccc cgagacgctg cgcaaggaac
    12121 tggccgccgc ggtcgcggcc cccggccggc tcaaacgctg gacgcgggtg gaactatggt
    12181 ccgcccacgc cctggtggaa ctccacatcg gcgaccggaa cgccgcccgg cgggccgccc
    12241 tcacgatcgc cgaggaacag tcgccggcgg gcgacttctc cggcagcccg gtcgccaccg
    12301 ccctcgcggc cctcgcgctc caggccgccg cgcccggcag cgccgccgcc caccgctgca
    12361 cggaacacct gatcgccggc caactcccgg acgggacctg gcgcttctcc accagcgacg
    12421 tctgggacac cgcgctgacc gtacgctcct ttcgcggcaa cccggccttc gaccgccacg
    12481 ggctgcccgc cgccgtcgcg ttcctggtcg cggcacagaa cccggacggt ggctggccgt
    12541 accgcctggg agtcgaatcc gacaacgaca ccaccgcggc cgccctgatc gcactggccg
    12601 gcgtggacga cggcgcgacg gccggtacgg tgcgggccgg gctgcgccat ctggcccggc
    12661 agcagacgtc cgacgggctc tggcggacct ggcagtccgc cggagaccct ccggtggacg
    12721 atgtcgtcgc ccatgtcgtc accgcgctcg accgccaccg cggccaccac cacgtaccgc
    12781 tggccgcggc gcgcacctgg ctcaccggcc gcttcggcga gcgggggcgc tggcaggccg
    12841 gctggtaccg gggcctgccg tacgccaccg ccgaggtcct gcccgctctc ggcacaacgg
    12901 cacaccacga aaagggcacg ccggcacacc acaacaaggg cacgacggca ctccacgaca
    12961 agggcacgac ggcgcaccac cagagcgcag cggtacattc cggcggcgcg acgccacacc
    13021 cgcccggaca ccccgccgcc cgcgctctgg ccgcaacccg caatcccgat ggcgggtggc
    13081 ccgtcgaggc aggcggaccg agcaccccgg ccgccaccgg cctggcgctc gccgccctgg
    13141 agcgcggcgg cctcgtcggc ggagaacacg acgagacgtg ctgggcaccc gggctcggcc
    13201 acctcctgga aacccagcgc ggagacggca cctggccggg cgtaccgctc atgtacggac
    13261 cgcggccgct gctgacccac ttccccaccc acacccacgc gttcgtcgtc gacggcctct
    13321 tcgccggaca gcgtcgcctc cgggctgccg ggggcgacgc cgcggccgcg cacaaggtgg
    13381 tctgacatgc ggacgagcat ggcgccgaaa cgttcctctg tcgaagttcc caccgccccc
    13441 ggccggctgc cactggccgg tcacgccccc tggctccacc gcgacgcgct gcgcttcgtc
    13501 cgcgaactgc gccggcacgg cccggtgacg aagatctaca tcggcccgcg ccccgtccac
    13561 gtcctcagct ccggcgaact gatccgggaa ctgctgaccg tgcgggcccg gtccttcgac
    13621 aaaggcgcga tgttcgacgc cctgcgggtg ccgctcggcg acggactgat caccgccgca
    13681 ggcgaccgcc acctacgcca ccgccggatg atgcagcccg cctttcacca cgagcggatc
    13741 gcccgctgca cccgcgtcat gaccgactgc tccggggccc gctccgccgc ctgggagccg
    13801 ggcaccacac gcgatctgat gccggacatc caccgcctga ctctcgacat cctgctcggc
    13861 accctcttcg cacaccccca ggaccccggc ctgcgccccg ccgtcaagga ctggctggcc
    13921 gtcaaatacc actcgatgcg cctcgcgctc tccccactgc acgcttgggc ggaacgcgtc
    13981 ccgctgctgc cgggctggcg tcccccggac cccggcccgc tgcgccgcct ggtggccgtc
    14041 ctgcggcgga tcgtcgagac ctaccgcgcc gacggccggg accacggcga cctgctctcg
    14101 atgctgctgc tcgccgaagg accggacgga gccctcaccg atgccgaggt gaccgacgag
    14161 ctgatcaccc tcttcctcgc gggcaccggc accgtcagcg ccgccctggc ctgggccctg
    14221 tacgagatct cccgccgccc cgaggtccag cggcgcctcc acgacgaact cgacaccgtc
    14281 cttgccggac ggccccccgg cttcgaggac ctgcccgccc tgatccacac ccggcagatc
    14341 ctgaccgaga cgctgcggct gcgcccgccc tcgtggctgc tcatgcgccg cgcggtacgg
    14401 ccggtccggc tcggcggcgt ccacctctcc ccgggggaag aggtcttttt cagcccgtac
    14461 gccctgcacc gtgatccgca cctgtacgag gaccccgagc gcttcgaccc cgagcgctgg
    14521 ccgcgcgaca gcgccgcgaa ggcaccgcgg cacctctacc tccccttcgg cgcgggcagc
    14581 cggctgtgta tcggagagga cttcgcctgg gccgaactga ccctggcact ggccgcgttc
    14641 accgcccacc gccgcatcgc accggctgac gccgcgccgc ccgtacggcc cctggtcggc
    14701 accgtcctcc gcccggaccg cctcctcctc accggccacc cccgccgcgc gttgtgattc
    14761 cgcatccctg cccaccgccc acctcgccag gagccctcca tgtcagtact cgcacagacg
    14821 ccggacaacg gagcccagct gggccgactg cacgatcggg tcgccctggt gaccggcggc
    14881 ggctccggca tcggcgcggt gtgcgcggga cggctggcgg aggaaggcgc cgtggtggtg
    14941 gtcgccgacc tggacgtgga cggcgcgacc cgggtggccg aggagatcac caaggcgggc
    15001 ggcaccgccc tgccccgccg gatcgacgtg accgacccgg acagcgtcgc ccgcgtcgta
    15061 tcggaggcgg ccggactgca cggcggcctg cggatcgcgg tcaacagcgc cgggaccaac
    15121 ggccccctcg tcccgctcgc ccagctggcg cccgctgact tcgacaccgt gatgagagtg
    15181 aacctctacg gcgtcttcca tgcgatgcgc tgccagctcc ccgcgatggc cgcgaccggt
    15241 ggtgccatcg tcaacatcgc ctccatagcg gcacattcgg gcttccgcgg ccatgccgcc
    15301 tacgccgccg ccaagcaggg cgtcctcgcc ctgacccgaa ccgcggcccg tgagtacgct
    15361 ggacagggcg tgcgggtcct gtcggtgtca ccgggcctcg tcgacacccc catggccgcc
    15421 gccctcccgc ccggcgcgac cgccgatctc ctcgcctccg tccccttgcg gcgcatcgcc
    15481 cagccgtcgg agatcgccgc gctcgtcgcc ttcctcgtgt ccgacgacgc ctcgtacctg
    15541 acgggtagcg accatgtgat cgacggcggc tacttggcca agtagcggac cctggcgacc
    15601 gtctaccacc gccctgacag cactcctccc ggcgtgaccg ccgccaatgc cggccgggcg
    15661 ctggccggcg gaaggggcgt gacgcccgga tgcccaaccg ccccggccgg cagtttcgtg
    15721 ccgaagagga acgggcccgt ggttacgtcc cgggctggca gtgacggtgg ccgccgacct
    15781 gctggtggtg gcagtgacga ccgtgcggtc gcacccgctg ccgttgcgcc acgtggttcg
    15841 gtcggcggtg cggacatggg agccgatcgg gaaggcgagt acatgcaacg tgccgggggc
    15901 gcggttgaag gcgcccatga cgatccggtt cggcacgtgc cgggtgccgg cgcggccggg
    15961 gctgcggtgc cgcggcgaga gcacgccggg cggaggaagc cgccgactcg gaggtctgcg
    16021 gccggccgga aaggatgctt gcgactccgt cgccgccgag ccacctctga ttttcattga
    16081 gtggacccat ccggccgcga ttccgcggag gttggcgtga acagctcgca cgacggggac
    16141 ggcaccggaa aggaatgttt cagcgaccga ggaggccggc cggcccacgc cgcagcgcgc
    16201 ggcggccgaa aagcgactcg tcccggcctg ggcggtcgta gcgtcgcgac atgaccactg
    16261 ccgacggcac ggcctacgtg ttccgcaccg cccgccccga ggacaccgac gccatcgagg
    16321 cgctcgacgg ctccttcacg accggcaccg tcttccgcgt ggaggtcgcc gacgacggat
    16381 tcacgctccg ggaggtccct gtggacccgc ccctgaccaa ggtcttcccc gaggacgagc
    16441 ccgacggcgg tgccgaggac ggggacgacg gcgaggaccc cggcagccgg accttcctcg
    16501 ccatcacggc cggcggtggc ctggccggat tcgtcgcggt ctcctactcc ccgtggaacc
    16561 gccggctcac cgtcgaggac atcgaggtgg cgccggacca ccgcggccgg ggagtcggcc
    16621 gtgcactgat ggagtgcgcc gggaagttcg ctcgcgagcg cggcgccggg cacatctggc
    16681 tggaggtcac caatgtcaac gccccggcga tccacgccta ccggcggatg ggcttcgcct
    16741 tctgcggact ggacacggtg ctctacgacg ggaccgcgtc cgagggcgag caagccctct
    16801 atatgagcaa gccctgtccc tgagccgaca gcaggcgtcc gacggcgggg gcgcttccgt
    16861 cgcccggcgc gatcgtgacg gtcagcagcc aggccgcgcc cccgtccggc cccgcgtgcg
    16921 gggcgtacca ctccacgcgc gcgtccagga gccggtcgcc ggccgcccgg cggtcggcat
    16981 accaggtagg gaacggtgcg gaccgccaca ccgtgagcgg caccgcccac tccccgcccg
    17041 tgcggcggga tcccgccccc accgcgcgca gggccgcgcc cgccgccccc aggagggtgc
    17101 gctccaccgg caccccgagc ccgtcggcga agtgcagcag atacgccatg cgttcggcct
    17161 cgggcggagc gccgagcacc gcccggcccg agcctcctcc tcccaggcga tctgatccgg
    17221 gtacgccggg taggcgcccc cgggggcggg ctcgggcaag aacaccgcga gccgccccgc
    17281 gtccgtccaa gcggcgcgca gggcggcgac ggcgtccgga cgccaggagg gctccgcggg
    17341 gccggcgggg tcggaccgca caagtagacg gctgccgccc atgcccccgg cggctcctgg
    17401 ccgacatgca cgacatggac agcggctgtt tccgcgttcc cggaggacac ggcagcggcg
    17461 gcagcggcgg cagcggactc agcggacacg gggccctccg gggtcggttg tggaaagggt
    17521 ggcgaggaag tccagcacgt cgtcggcgaa ccccaccacc agcaggggtg tggtgatccg
    17581 ggcgtagtcg gccagccggt tccggaccgg cggctgcggg cggtgcgcgg cggaggtgcc
    17641 ggtgagcgcg gccacttcga acaagtcgag ccattctgct gcagcgccct cgtccgccag
    17701 ggttctgggg gagaggttct gcaccaggcg cacgaacgct tcgtactccg gtgggagccg
    17761 ggttcccgcc tcggcgtacg cggcttcggc gcgggccagt gcctcgccga ccggatcggg
    17821 ccggccctga tctcgatcgt gcaccgcctg gactccgtcc gggaagccga ccgcatcgcg
    17881 gtcatggacc gcggccgcat cgtcgaactc ggcagccacg aggagctcct ggcggcggag
    17941 ggggcctatg cagctctgtg gcacgcgtgg gattcggcac gcgggcgggg cgcctgacgg
    18001 caaccgaccg gagacccgaa gccgcgcgtt ctccggcacc aagttctccc cctcaccatg
    18061 gtcaccggcg acccgcaagg agccgtcgcc atcgccaacc gcgccctgga cgaggtcgga
    18121 cgtctgcgct cccgccgcgc ggccgaagac ctccgggaac tcttccgcta ctccagccac
    18181 cacagcaagc agccggacgt gaccgagctg cgccgccgca tcaccacggc gccggcctga
    18241 ccagcccacg ggaacaggct tcccgccgca tcgcccgcct cggccggcac caggcggcag
    18301 cccgggaagt cgccgtcacc cgctggctcg ccacccacca cctgccggcc gtgcggcccc
    18361 tgctcatcga ccagcccgtc cacgcccgag aacgcgccgt caccttctgg gaagagctcc
    18421 caccgcaccg gcacggaacc cccggcgaga tggcacccct gctccagcgc ctgcacgctt
    18481 tgcccatccc ggatatcgac cttggacagc tcgacccctt cgtcaggatc gaacagcgcc
    18541 tgacagcctc cacaccggtg taggccgacg acagggactg tctcctgcac cacctcacag
    18601 acctacacgc gatctgggcg gaactacccg gcgggctgcc ccgctgcgtg aatcgccgcc
    18661 cggcacccct ccggcggccg gatgcggcat gcagctgctg ctcagttcac tggaaagagc
    18721 gcagacggtt tgaactcgcc ggccgcgcca cgccacccac acactgtcgc tgccccgccc
    18781 cgggtacatc ggcgcgaggc cgggcaccaa gagcacgcac ttgacgtcat gaggctcgcg
    18841 cccctcgcac gggagtttgg cgacggtccc caggcgaact caatgcctaa gcagccacaa
    18901 cacccgatcc cacgatagaa ggtggtgcat gaccagcacc ccggcgagca tcacggccgg
    18961 agtgcggaaa tccgtggcgt acaacgccgc cgcgctaccg aagaagacgg ccagctccag
    19021 caggagtcgc agcagaccag gtgtcgcaat cacggtccct ccggaccggg acgcatcacc
    19081 gggggtggca aatactcccc acagcacggc cgcgaccagg ggaacggcaa ccacaaagac
    19141 gtactgcaga ggagcaggcg ccgtaaccca tgcccagagc ccgaagcaca tcagagccac
    19201 cagctccaac acgaacctca cgccgagagt caacgggtga aagccatacc cggacacacg
    19261 cgcaatctcc ttccttccgt cgcagccccc gtgatcacag agcgccgaac ggcaggggtc
    19321 tccggcggca cccgccgtcg ctcgccatcg cgtctccgca ggccggccag gctcagcgcc
    19381 gattagatcc gcttcaggtt tctgtccaga accacccgga actggtccac gtccgcaggg
    19441 ccctgggccc ctcgcttggg caccaccgag actccggccg cgcgctcacc gcccagcagc
    19501 acgaagagcc ccggagtctc caggtactcc cggaacaccg tccagtcgtg ggtaaaggac
    19561 actcgctcgc cggtactggc catgccacgg tcgtcggcga ccacacggca ctgcccgtac
    19621 ggctccacga tgctgaacat ccggcgggcc atggtgcgca gcccacgcac agtgccccag
    19681 gacgcggctg cgacggagag caccagcgcg gtgatccaca cgggcaatgc gatatcacgg
    19741 agcacggcga aggcggccac gccggccgca gccatcaggg gtccgagcag cgcctgggtc
    19801 cggcccgctg ctgtccggcg ggctcgcgca cgcagcgcct cttcgaagtc cgcggccgtc
    19861 ggctggtaga cgaactccac ggacttgccg cgacctgtgt tttgaggcag gaaagccgct
    19921 gtcgctcggg ccagctctgt gtcgtactgg tcggcgtcga accggtactc agggggcagc
    19981 ttcccactgt ccccgctgtt ctcccaatcc gtccagagca tgtgggagcc ctcgcggcgg
    20041 atggtcaccc agaccgagcc gcagcaagta gtgctgcact ccgccgccgt cagcatcacc
    20101 ttgcgaccgg cctccgtcgc agccagtgga atgccctgcc accacgaggt ggtgccctcg
    20161 gggtagacgt cctcgatgac gtcctgcccg ttgatcagcg ggcggatctc accgtgctgc
    20221 tccgggtgaa cgttgtcctc ggggccttgt tggcgaaggg cgaaaatgct tatctcgtgt
    20281 gacaccggat gattatgcgc cacactttcg gcacctccgg cctgcccggc gctgacgaac
    20341 aacgtggcaa ggcccgtgac gatgcacgcc acgaagagtc gccggtactt gaaactggcc
    20401 accctggaca aggccaccac ccggtgtggg caggtatccc cctcccgttc cacagacgca
    20461 ttcaggcgcg ccatcaccga gcggcgacgg cggctgcacc gatcgagtgg gctcccgccc
    20521 tccttgcgca ggcgtagccg gccagcgccg cctcggggcg agatgtcacg ttgatgattc
    20581 actgcctggc ccgctcggct gcttgccatg tgagtttgtg agcttgctgt tcgttacagg
    20641 cgcccctgtg cctgctggcc tccttgctgg gcagcagggc ttgtgagcca acaggggcgc
    20701 ggcctctcac caccgcgcgc ccctgccaca cgccttctac tatcagacaa tctgagcgca
    20761 cacttcaggc catggcgaga ggctctgccg gagcgccagc cactgcggac tatccgttca
    20821 gcgcgaggcc tcgcacgcgc agctcccact cgccccccgt gcgtcccgca gacgcccggc
    20881 ccgagattga tcccttcgag ccgattgtgc cggcgtggcc acctttcgta tcccctatgt
    20941 tgcccggtta cgccgcatcc caagggtgtg gccgggtgga gaggagcact gcgccgaacc
    21001 tgagctacgt gcccgcaagg actgtcgttc caaggaggtc gcatgtcccg cacactgtcc
    21061 aggatcgtga cgtctgctgc cgcagtgggc tgcctggccg ccgccatggt ggtcggcccc
    21121 acatccgccc aggcggcacc gccctgcccc gcaacggatg ctgtctgcca gtacagcgga
    21181 gtgttcttca cgggctcgac cgacattgac cggcgcccgc tgaccggcac ctgtacgcag
    21241 gtcgacttcc cgggtgccaa caacggcact gcgctttcgg tccgcaacaa cacgtcacat
    21301 gttctcgtcg agttcctcga cgagaactgc acggttcccg ccggtgccag cgtgcaaccc
    21361 ttcggcaacc agccggccgg aagctacagc agttacctcc tcgacgtcat cggctgagcg
    21421 cgcacccgca cccgacgtca tgacgccctg agatccggcg tcataaagcg tccaacgcgg
    21481 ggtccggtcg ccgccaccgg tgacaccacg agggcggtgc cgcttcggac accccctcgc
    21541 catcccactg ctggcgacgg ccggcttgcg ggcacgccga taggtcgatt cgtctacaga
    21601 cttcgttgtg tcgtcacatg aggcacggct tgagcaaccg ccgagggcgt gtccggtgga
    21661 gacaaggtct catcgggcac gccttagaag tcctaacgaa atgatcttca aggtggttgg
    21721 atcactccga gattgatgat ctgggggtgt ggggtggctc gatcgaagcc gtgggaagtc
    21781 gatgacgagc tgtgggcggt gatcgagcgg ctgctaccga aggtggagcg tcggcccctg
    21841 catcccgggc gtaggcggca tccggaccgg ctggtgttcc agggcatcct gttcgtcctg
    21901 cacacgggga tcgcctggga acatctgccg caggagctcg gcttcggctc gggtatgacc
    21961 tgctggcgcc gcttggccga gtggaccgag gctggagtct ggccccggct gcacggggtc
    22021 ctcctggcca agcttcgcag cgcgaacgcc ctggacttct cccgggcggc tgtcgacggc
    22081 tcccacatac gggcgttaaa ggcggatcca agacgggacg aagccccgtt gaccggggta
    22141 ggacgggcag caagtatcac ctgatcaccg acgccactgg tatcccgctc gccgccacct
    22201 tgaccggcgg caaccgccac gacgtcaccc agctgatccc gctgcttcag gcggtaccgc
    22261 cggtgcgggg caagcgaggc cggccccggc accgcccgga cgtggtgctg ggcgaccgcg
    22321 gctacgacca cgacaagtac cgccgcctcg tccgggatct cggcgtgaag ccgctgatcg
    22381 cccgccgggg caccgagcat ggctccggac tcggcgccca acgctgggtc gtggagcgag
    22441 cattcgcccg cctgcactgg ttccgccgcc tgcgggtccg ctgggagata cgcgacgaca
    22501 tccacgaagc cttcctcacc ctcggatgcg cactgatctg ctggcgacgt ctgaactccc
    22561 ggtaggagtt tcaagacagg cacggcttac tttgacggcc cggtggccga cctcaggttg
    22621 gcttgcgcca cacggagatg tgcttcgcgg agtcctgggt gaacggcgcc ccgtcccagt
    22681 ccgcgacgcg acgttccatc tcgagcccag cgatccgtgc catcaggtcg agctctgccg
    22741 gccaggcgta gcggtgccgg gagttgtcgc ggcggtagcg gccgtcgtcg ccgtcgcggg
    22801 tgaagtggtg cgagacgaga atctgctcga cgaggtcgaa tgtgtcgaag ccgagatgct
    22861 gctcagagac gtcgaacggc accgcgacct ggccgggcgg caggaaccgc agcggcggca
    22921 cgcccagctc gatgacgaat cggccgccgg gctccagatg acgtgcggcg ttgcggaagc
    22981 actcgacctg ctcgtcctga gtgagcaggt tcgtgatggt gttgtagacg agatagacca
    23041 gggtgaactc gccgggaacg acggtggtgg ccatgtcccc gatgactacc gggagcgtgt
    23101 cctcgtcgat cttgcgccgc agcaccgctg ccatgtgctc ggacagttcg atgcccacta
    23161 ccggcacgcc gcgttcccgg agcggaacgc ccactcgtcc ggtcccgatg gcgaactcca
    23221 gtgcccggcc gtctccggcg agctcggcga ggaaggcgag agccggtccg agaacggcgg
    23281 ccgaggacgt ctcggtctcc tcggcgtcgt agcggtcggc ggtcgcacgg gtccacagct
    23341 cactgctcgt cacgggcggc cactttgccg ggtaccgagg ggcgc
//
