LOCUS       NZ_CP040752            21074 bp    DNA     linear   CON 05-MAY-2024
DEFINITION  Streptomyces rectiverticillatus strain B15-08 chromosome, complete
            genome.
ACCESSION   NZ_CP040752
VERSION     NZ_CP040752.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces rectiverticillatus
  ORGANISM  Streptomyces rectiverticillatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7679243)
  AUTHORS   Park,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAY-2019) Laboratory of Bioorganic Chemistry, NIDDK,
            NIH, 9000 Rockville Pike, Bethesda, MD 20892, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: DEC-2018
            Assembly Method                   :: HGAP v. Dec-2018
            Assembly Name                     :: DDK_LBC_B15-08
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013394065.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 03:49:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,642
            CDSs (total)                      :: 6,543
            Genes (coding)                    :: 6,394
            CDSs (with protein)               :: 6,394
            Genes (RNA)                       :: 99
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 55 of 149
            Pseudo Genes (incomplete)         :: 125 of 149
            Pseudo Genes (internal stop)      :: 12 of 149
            Pseudo Genes (multiple problems)  :: 41 of 149
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:46:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 934862
            Orig. end                         :: 955936
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040752.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from LBC, NIDDK.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21074
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /product="RiPP-like"
                     /region_number="13"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..21074
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="neighbouring"
                     /product="terpene-precursor"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..21074
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11074](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11074
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(364..1551)
                     /locus_tag="FGW37_RS03685"
                     /old_locus_tag="FGW37_03755"
     CDS             complement(364..1551)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069051.1"
                     /locus_tag="FGW37_RS03685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_03755"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_179079732.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 7.7e-24, bitscore:
                     83.1, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7e-20, bitscore:
                     69.6, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.9e-29, bitscore:
                     101.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLEYTPEQRRFRAELRDYFAGLVAGRAHARHDDPAEQKRFYRAT
                     IRRLGADGRLGVGWPAEYGGSGRTPMEQFIFFDEAAQAGVPLPLMALNTVGPTLMQFGT
                     DEQKAYFLPRILSGELDFAIGYSEPGAGTDLASLTTRAVRDGDSYVVNGQKIWTTNGDT
                     ADWIWLAVRTTPVTEGTPPHKGITLLLVPTSAPGYSCTTINTLASHSTTAGYYENVRVP
                     VRNRVGEENKGWRLITTQLNHERVTLAAHGTTAVGALRDVRRWAAATELADGRRVIDLG
                     WVRARLARTHLRLEAMKLLNWQMVDALQRSALTPQDASAVKVYGSETRRDAYAWLMEVL
                     AAAGPLKEGSAGAALHGELERGYRAAVVFTFGGGNNEIQREIISWIGLGMPRVRR"
     misc_feature    1606..1620
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.9"
                     /tool="antismash"
     gene            complement(1737..2546)
                     /locus_tag="FGW37_RS03690"
                     /old_locus_tag="FGW37_03760"
     CDS             complement(1737..2546)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004956382.1"
                     /locus_tag="FGW37_RS03690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_03760"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_179079733.1"
                     /transl_table=11
                     /translation="MPYVRHWLRNSVLLFAVAIALGLVAVHTDLIQPHDLKLDRTVQTT
                     FRTEWLNVVMEGVSALASPVAGLLILAVWCGWLLFVRRRPVTAVSTFLVVAVGWNSTQI
                     AKAVVARPRPPREFMLDPEIGSNSFPSGHTAFTVAAFIAAYFLFRESRHRRTVAVVGVF
                     AVLLIAFSRWYVGAHYPTDTLGSVLIASSAIIFVTGVWHAWLLPRLYRIPLLERFGLDQ
                     ELAELEAAEQHGGHHGHTRPVPHSRRRGGGGGGGTPTGGRHRRHAAR"
     cand_cluster    2351..13584
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    2351..13584
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[<7350:8584](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(<7351..8584)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
     misc_feature    complement(2625..2637)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     misc_feature    2902..2917
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.8"
                     /tool="antismash"
     gene            3041..4303
                     /locus_tag="FGW37_RS03695"
                     /old_locus_tag="FGW37_03765"
     CDS             3041..4303
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010473878.1"
                     /locus_tag="FGW37_RS03695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_03765"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_179079734.1"
                     /transl_table=11
                     /translation="MNIRTRTVHRALAGALAAAAMAAAALTAPAAARAAGTTAAGGREA
                     AAGHDRHAATRSAMEAQVAAGIPGVLGQARDDHGTWRGSAGIADRTTERPRLAQDRFRI
                     ASVSKVFTSVVLLQLEAEGRIGLDDPVERWLPGVVRGGGHDGREITVRQLLNHTSGIYN
                     YTEDPRFQKLLGPDFLEHRFDDHTPDELVKTAMAHAPYFRPGGGWHYSNTNYVLAGMVV
                     EKVTGRSYATEIKRRIIRPLGLTATTLPGTAPELPGPHGRAYSTLLAEPAPDPKIYDVT
                     ELNPSWGGAAGEIISTTGDLNRFYGALIGGKLLPRAQQRELLTGVSVDDQMPGVRYGLG
                     VYTAPLSCGVTVWMHTGGVHGSETIASATADGRHTAAFNFNGDWTGDLGALVEAEYCGK
                     APSGKSAVAGPQKTTTLMAPR"
     gene            complement(4382..6001)
                     /locus_tag="FGW37_RS03700"
                     /old_locus_tag="FGW37_03770"
     CDS             complement(4382..6001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004956185.1"
                     /locus_tag="FGW37_RS03700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_03770"
                     /product="phospholipase D-like domain-containing protein"
                     /protein_id="WP_179079735.1"
                     /transl_table=11
                     /translation="MARLRLRRLTRPAVSAAVSALALAALPAAPALADSSATPHLDAVE
                     QTLRQVSPGLEGRVWERTAGNTLDASSGDPGDWLLQTPGCWGDATCAERPGTKRLLAKM
                     TENISRATRTVDISTLAPFPDGAFQDAIVAGLKKSVENGNKPKVRVLVGAAPVYHMNVL
                     PTKYRDDLRDKLGKAAGSVTLNVASMTTSKTAFSWNHSKLLVVDGQSAITGGINSWKGD
                     YVDTTHPVSDVDLALTGPAAGSAGRYLDQLWTWTCGNKSNIASVWFAASDGAACMPTME
                     KDANPVAAPATGNVPVIAVGGLGVGIQDSDPSSSFRPDLPTAPDTKCVVGLHDNTNADR
                     DYDTANPEESALRALVASARSHVEISQQDLNATCPPLPRYDIRLYDALAAKLAAGVKVR
                     IVVSDPANRGAVGSGGYSQIKSLNEISDVLRNRLAPLTGGQQGAKAAMCGNLQLATARS
                     SDSAKWADGKPYAQHHKLVSVDGSAFYIGSKNLYPSWLQDFGYMVESPQAAQQLDANLL
                     APQWKYSQATATFDYARGICQG"
     misc_feature    complement(5975..5977)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6140..7171)
                     /locus_tag="FGW37_RS03705"
                     /old_locus_tag="FGW37_03775"
     CDS             complement(6140..7171)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04222.1"
                     /locus_tag="FGW37_RS03705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_03775"
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_179079736.1"
                     /transl_table=11
                     /translation="MIAGIVVASLVTLLALVAPSAWLVVARRRALADPPPAQGEPELLE
                     VAYLLGGRNRVVDTVIAGMCDDGRISVNESGKLKVERAAAYNAVERALLGRCGADWSIS
                     LRRVRTSLKFDPAVDALEGALVRRGMLVSPVVKQKWQRAADVQVAGLVLTGVGVVALVL
                     MPASFVTAFVVLGLLVAGIVLRVRCRPAGPKVRPTPRGKAFIERTPATGPWSARFSATH
                     PEGIAGVVAVHGAGGPEPDQPFLGQLRQAALPSPGVGSVRSYSKGAKKPPSRKTAKSSS
                     SSSSSSSSSSSHTSGGYGCSGASSCSSHSGHSSHSGHSSCSSSSCSSSSSSSSCGGGSS
                     CGS"
     gene            complement(<7351..8584)
                     /locus_tag="FGW37_RS03710"
                     /old_locus_tag="FGW37_03780"
                     /pseudo=""
     CDS             complement(<7351..8584)
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238120.1"
                     /locus_tag="FGW37_RS03710"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="FGW37_03780"
                     /product="DUF692 family multinuclear iron-containing
                     protein"
                     /pseudo=""
                     /sec_met_domain="DUF692 (E-value: 2.8e-91, bitscore: 304.0,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEPSALKSLGTGIGWRPETADAVAAGRVRADWVEVVAENVCPCH
                     LPGPLRELRERGTTVIPHGVSLGLGGADRPDLARLAALAERAEALGSPLVSEHIAFVRS
                     GGPLTGSPRIEAGHLLPVPRTRDALDVLCENVRIAQDMLPVPLALENIAALLPWPGEEL
                     TEGQFLAELVARTGVRLLIDVANLHTNHVNLGQDPAASLDELPLEAIAYVHVAGGVEQG
                     GLWHDSHAHPVTGPVLDVLAELCARVTPPGVLLERDDAFPAPEELAAELDAIRATVAGA
                     RRSSRQDRQDRQDRQRTVAHSV"
     misc_feature    8632..8647
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.41"
                     /tool="antismash"
     misc_feature    complement(8663..8681)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.39"
                     /tool="antismash"
     misc_feature    complement(8797..8810)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.53"
                     /tool="antismash"
     gene            8886..9956
                     /locus_tag="FGW37_RS03715"
                     /old_locus_tag="FGW37_03785"
     CDS             8886..9956
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016906849.1"
                     /locus_tag="FGW37_RS03715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_03785"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_179079737.1"
                     /transl_table=11
                     /translation="MYGKAFAPEYRGSLEDLSVNASLEEVLSKAVEQRRRAQLDGSALD
                     MAHAELAVAEASRRLGRVEDAERAWKASYRAARQAADLGAMAWAVWSGGTLARQRGTLA
                     LARRWLAIAAELAERGDDIVARGYSLAGLAETGRIQGDYQAVGELHEKLLAEARRRGEA
                     RHTVWALEGIAQMHRNSGSYDTALAMFEEAAEISGRADDARGHAWALRGIADVLSLRGE
                     TERALALLSEAEGTCRRMKLVSALAYNHKMRGNVLFRAGRYAEAEECYRGALEEFREMA
                     EPRGAALARLGLVKSRARLGHDRAETAAELDDLHRTLGRIGLLHARRMVEAARAELGMP
                     AEPAAAPAAPAARPAA"
     gene            10001..11074
                     /locus_tag="FGW37_RS03720"
                     /old_locus_tag="FGW37_03790"
     CDS             10001..11074
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377851.1"
                     /locus_tag="FGW37_RS03720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_03790"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_179079738.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-54, bitscore:
                     184.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTQAGPVPPQTALRTPAPQTLARARALAEPALRAAVATLHPLPA
                     RMAAFSFGWCEADGTPSPSPGGKGVRQAFALLGAETVGAPLGTAVQAAVAVELVHTFSL
                     VHDDIMDGDERRRHRDATWKAFGTGPAVLTGDALFALAVRTVAEAGGEHTGRAVAHLAD
                     CLGELVRGQADDLLFENRPWTGRGAVGIPEYEAMAARKTGALLGCALSLGPVLAGAPPL
                     QTGALAEAGRRLGTAFQIVDDLLGIWGDPRTTGKPVHGDLLRRKKTLPVLAAVALDDGA
                     TARELARLLGPDTPPAAAAARRAAGLVEAAGGREFALEEAHRHAAAAHDCLRGAGLAEG
                     AVGELVALSAHLLERRL"
     gene            complement(11125..12726)
                     /locus_tag="FGW37_RS03725"
                     /old_locus_tag="FGW37_03795"
     CDS             complement(11125..12726)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (114-495). E-value:
                     8.7e-19. Score: 60.0. Matches aSDomain:
                     nrpspksdomains_FGW37_RS03725_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004953346.1"
                     /locus_tag="FGW37_RS03725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_03795"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_246430251.1"
                     /sec_met_domain="PF00561 (E-value: 5.5e-23, bitscore: 80.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFELRKSRRTVPAVSALAAVSAALAAVVAAAMLPAGTAAAQQSAA
                     AQPRPATAVTVPERYTSQKLAWQPCPEPATMECAEMTVPRDWHAPDTGKDLTIAVSRVR
                     ASDPAHRRGVLMMAAGGPGGKGLLRPAGVARQAPAIGAVHDIVSFDQRGVGRSTPLQCQ
                     TQDELDAFFAGDFRDRSPAAVQRVVDNSRKLADACREKHGDLLPYITTEQTVRDMDLFR
                     ALLGERKISYYGASYATMVGAYYATLFPQRVERAVLDSNIAFGGTWEDFEKGQPKSFQR
                     RFEQDFLPWLAKNDATYHYGRTAAEAKATWERRRSALRDHPISPGEGKGRTLDPNRFDS
                     GTIQAIYDSQEGFPGLAKTLAALEHWDTASPAERKLVDTVFGSYLGTNFFAEFLAVTCA
                     DTPWNRDTGSWVRRSAEDTAKYPLMGARELAFASACAAWPASPAPRVKVTGKGLPPVLM
                     LNSLHDPATYYEGAQRAHRDLRGSRLVTDTGGDHGVYLGGSACADGIVNKYLLSGELPA
                     RDVTCKAAPLPVPTAK"
     aSDomain        complement(11242..12384)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FGW37_RS03725_Abhydrolase_1.1"
                     /evalue="8.70E-19"
                     /label="FGW37_RS03725_Abhydrolase_1.1"
                     /locus_tag="FGW37_RS03725"
                     /protein_end="495"
                     /protein_start="114"
                     /score="60.0"
                     /tool="antismash"
                     /translation="LMMAAGGPGGKGLLRPAGVARQAPAIGAVHDIVSFDQRGVGRSTP
                     LQCQTQDELDAFFAGDFRDRSPAAVQRVVDNSRKLADACREKHGDLLPYITTEQTVRDM
                     DLFRALLGERKISYYGASYATMVGAYYATLFPQRVERAVLDSNIAFGGTWEDFEKGQPK
                     SFQRRFEQDFLPWLAKNDATYHYGRTAAEAKATWERRRSALRDHPISPGEGKGRTLDPN
                     RFDSGTIQAIYDSQEGFPGLAKTLAALEHWDTASPAERKLVDTVFGSYLGTNFFAEFLA
                     VTCADTPWNRDTGSWVRRSAEDTAKYPLMGARELAFASACAAWPASPAPRVKVTGKGLP
                     PVLMLNSLHDPATYYEGAQRAHRDLRGSRLVTDTGGDHGVY"
     gene            complement(12848..13990)
                     /locus_tag="FGW37_RS03730"
                     /old_locus_tag="FGW37_03800"
     CDS             complement(12848..13990)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003974614.1"
                     /locus_tag="FGW37_RS03730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_03800"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_179079739.1"
                     /transl_table=11
                     /translation="MLWKSRKTSRRSFVAAALLAAFAAPQIPAVAAAVERAPEPSASGT
                     PARVPAPTGKQPVGTKTLHLVDTSRPDPWKPAAGKRQLMVSLWYPARHQGDRNAPYVSK
                     ELSKAVLGKEDLAGVRTNSTLGAEPARKPRPLVVLSPGFGLSRLTLTTLGEDLASRGYA
                     VAAVDHTYEAPVEFPGGRIETCEICAKPDMAAVVRNRAKDFSFLLDRLTAPGSPLAVDR
                     SRIAVVGHSIGGASAVEALRGDKRVDAAVNLDGNFPSDLPADGLNKPVLLFGAQRAGNT
                     ENWDKNWQRLTGWKRWLDVPEGGHLTFTDAPWIVDRFGMPGQIPPDQVHGAYGSLHGTR
                     STALTRAYVNAFLDRHLRGTPSPLLDRPSAAYPEVTILKK"
     misc_feature    complement(13984..13998)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.48"
                     /tool="antismash"
     misc_feature    13998..14015
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.76"
                     /tool="antismash"
     gene            complement(14075..15235)
                     /locus_tag="FGW37_RS03735"
                     /old_locus_tag="FGW37_03805"
     CDS             complement(14075..15235)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004948811.1"
                     /locus_tag="FGW37_RS03735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_03805"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_179079740.1"
                     /transl_table=11
                     /translation="MGRFKRTLVAAALAATVVAGTAGWAVSDEQAVVTGPPAGAEAWRA
                     DHSLHRELPDPATAAPRTVAAFFAGLTEAQRKDLAARHALVVGNLDGAPVPLRYEANAR
                     AIAAEREKAQARVADPGLTRAAREEARERADRCERLLAPGRRILAFDPRGRGQVAEVYG
                     DLAAARHTAVIVPGSDIDLRTFDRTKDRYGTPAGMAASLRAEMERRAPGTPTAVIAWAG
                     YTTPVGLGVDAATGRLAQAGAVRLERLLSGLAAAAASPAAPPPAVFCHSYGSVVCGLAA
                     PSVDRTEAADLVALGSPGMRADSVAGLHTGARVWAAARNSSDWIGNVPNVDLFGLGHGT
                     DPTSPGFGARIVPTLGAHGHTGYFAPGTDSLRNFAHIALGAYASVR"
     gene            complement(15362..15850)
                     /locus_tag="FGW37_RS03740"
                     /old_locus_tag="FGW37_03810"
     CDS             complement(15362..15850)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018889297.1"
                     /locus_tag="FGW37_RS03740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_03810"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_179079741.1"
                     /transl_table=11
                     /translation="MADSTSGSTSGISELVALLGLQPHVEGGWFRETWKTSREAVPDGY
                     GGPRAFATGIYYLLHPGEVSRWHRVRSDELWLWHRGGPLRMRLGGSGDRPDGKEASEVV
                     VGPGVERGEQPQFLVPGGVWQSAEPAGDEPVLVTCVVAPGFDYEDFEDSVDSEDPARG"
     gene            complement(15855..16073)
                     /locus_tag="FGW37_RS03745"
                     /old_locus_tag="FGW37_03815"
     CDS             complement(15855..16073)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016469751.1"
                     /locus_tag="FGW37_RS03745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_03815"
                     /product="hypothetical protein"
                     /protein_id="WP_179079742.1"
                     /transl_table=11
                     /translation="MKKLLEGVGVILVLQGLGGVVHGLTGWFHYWVVVRYLGFLDGYEM
                     YASIVLAVIGAALVIASDAVKAEAARE"
     gene            16253..17437
                     /locus_tag="FGW37_RS03750"
                     /old_locus_tag="FGW37_03820"
     CDS             16253..17437
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388111.1"
                     /locus_tag="FGW37_RS03750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_03820"
                     /product="histidine kinase"
                     /protein_id="WP_179079743.1"
                     /transl_table=11
                     /translation="MDVKTEETAEVRPRRARSVRDWAVDILCIALAAVIGILAAEALRK
                     APDPSPALLFFDQIVGALACVALWMRRRWPVPLAVVLVVVSTPVPPAAGAMLVAVFTVA
                     VHRPFRTVAAVGGLALISEPLQAAIRPDPDLPFPAATATGLLLVLTVIGWGMFVRSRRQ
                     LVLSLRERARRAEAEAQLRAEQAQRLARERIAREMHDVLAHRLSLLCVHAGALEFRPDA
                     PPAEVARAAGVIRDSAHQALEDLREVIGVLRAPGAEGGGDRPQPTLAALEELVEESRQA
                     GTEVVLVQRVADAPAVPEATGRTVYRIVQEALTNARKHAGGAAVRVTVEGSPEAGLTVG
                     ITNPPGDGSGASVPGSGQGLIGLAERAALAGGRLSHGPTPDGGFRIDGWLPWRP"
     gene            17434..18177
                     /locus_tag="FGW37_RS03755"
                     /old_locus_tag="FGW37_03825"
     CDS             17434..18177
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018381573.1"
                     /locus_tag="FGW37_RS03755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_03825"
                     /product="response regulator transcription factor"
                     /protein_id="WP_179079744.1"
                     /transl_table=11
                     /translation="MNAPQPPHGTEPSHSPGAQAQQSPQGRPIRVLLVDDDPLVRAGLS
                     FMLGGLPDIRIVGEAADGSEVTALVDRHAPDVVLMDIRMPSVDGLAATEELRRREDAPE
                     VVVLTTFHADEQVLRALRAGAAGFVLKDTPPAEIVAAVRRVAAGEPVLSPAVTQQLITR
                     VTERERDTRGDRARALLAALNDREREVAACVGRGQSNAEIAGALYMSVATVKTHVSRIL
                     TKLGLNNRVQIALLVHDAGGPGAEA"
     misc_feature    complement(18375..18384)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.63"
                     /tool="antismash"
     misc_feature    18416..18431
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.61"
                     /tool="antismash"
     misc_feature    complement(18417..18430)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.35"
                     /tool="antismash"
     gene            18503..20686
                     /locus_tag="FGW37_RS03760"
                     /old_locus_tag="FGW37_03830"
     CDS             18503..20686
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004948806.1"
                     /locus_tag="FGW37_RS03760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGW37_03830"
                     /product="PIG-L family deacetylase"
                     /protein_id="WP_179079745.1"
                     /sec_met_domain="PIG-L (E-value: 1.3e-11, bitscore: 43.9,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGHIPRRRVLQVAGGGIVVGAGAVGAWQWLSPEAKKKAAQDGAP
                     VRPAKATTSESFVHVIAHPDDSLYFMNPELEQSILGGGPSVTVCLTGGESDGRNELSGA
                     RGYKRLPEKRGEFVRARLNGFREATAQMATGDWLSPWTVEALSLLPGIQVELHTLRAAP
                     QVQLIFLELVEARTLRNPRKESLRGLWLGATPQLTTLRPAASPVRSTFQYGRKQLIDTL
                     VAIFERYQPTVVRTLDPNPTHLPKPPEFPNTPPVLRGIAKYDHQDHTTSAFFAQAALAE
                     YWGRKHARPTAVDSYVGYEVSHLPSNLDKATTDHKLKFLDTYGWADGKDCGDAAGCGDR
                     KVGRTSGTKYHGWSSNCRHRAPGTMRWVQPLPDGRLAAFAVLDGAAQCWTEAKAGSGIW
                     STPTSLGGSMLEGQVQALRHSDGTLQLFSIRTVLPGKDTPHRREVVTALQSGDGSGDGS
                     GGTPSFGPWESLGSPEQDPARSMEMGYPVAVAGTDGTVHVFVRTFEGEVSRRSGAGGKD
                     FSEWETLPSAGPRVRLEDGLDAALDGQGRIHLVAADTKTVHHWMSQGPGGPLQPAEPTK
                     LPAVTGPLSLAPLASGGMRMAVRQPNTSRVLVVDRLGDDKGWRVSAQCDPLNGHGRVAV
                     GQAGNTTVLTDHDGKGRVRLSAGSGRPGPWGKDGIPYRGVPGVALDAKGNAVAVVVMGL
                     DNKLSSARLRGPGKGAFTDWIAHDGKARTNVQS"
     misc_feature    20826..20840
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.83"
                     /tool="antismash"
     misc_feature    20864..20877
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
ORIGIN
        1 cacccacagg agcagggcgg ggtcgtcgac gggatagcgc gcgccggtgt ccgggtcggt
       61 ggcggacagc cggcggtgga tgccgcggac ggccgctccc gcgcgctcgg cggcctcggt
      121 ggtgccgtag gtggtggtgc ccacgaagtt cgcggtgcgc agcaggcggc cccaggcgtc
      181 cttgcggaag tcggagttct gcatgacgcc gcggaccgcg cgcgggtgca gcgcctggag
      241 ccacagggcg cgcaccccgg cgatccacat catggggtcg ccgtgcagct gccaggtgac
      301 cgatgcgggc ccgaagagcc cggggtcggc gtgcggcatg gggcacctcc tgtcatcgtc
      361 aggttagcgg cgcacgcgcg gcatccccag gccgatccag gagatgatct cccgctggat
      421 ctcgttgttg ccgccgccga aggtgaagac gacggcggcg cggtagccgc gttcgagttc
      481 gccgtggagg gcggcgccgg cggagccttc cttgaggggt cccgccgcgg cgaggacctc
      541 catgagccag gcgtacgcgt cgcggcgggt ctcggagccg tagaccttga cggcggaggc
      601 gtcctgcggg gtgagcgccg agcgctgcag ggcgtcgacc atctgccagt tgagcagctt
      661 catcgcctcc aggcgcaggt gggtgcgggc gagccgggcg cggacccagc cgaggtcgat
      721 gacgcggcgg ccgtcggcga gctcggtggc ggcggcccag cgccgtacgt cgcgcagggc
      781 gccgacggcc gtggtgccgt gggcggcgag ggtgacgcgc tcgtggttga gctgagtggt
      841 gatcagccgc cagcccttgt tctcctcgcc gacgcggttg cggacgggga cgcggacgtt
      901 ctcgtagtag ccggcggtcg tgctgtggga ggcgagggtg ttgatggtgg tgcaggagta
      961 accgggggcg ctggtcggca cgaggaggag ggtgatgccc ttgtgcggcg gggtgccctc
     1021 ggtgacgggg gtggtgcgga cggccagcca gatccagtcg gcggtgtcgc cgttggtggt
     1081 ccagatcttc tggccgttga ccacgtagga gtcgccgtcg cggacggccc gcgtcgtgag
     1141 ggaggcgagg tcggtgccgg cgccgggctc gctgtagccg atggcgaagt cgagctcgcc
     1201 cgagaggatc cggggcagga agtacgcctt ctgctcgtcc gtgccgaact gcatgagggt
     1261 ggggccgacg gtgttcagcg ccatcagggg cagcggcacg cccgcctgcg cggcctcgtc
     1321 gaagaagatg aactgttcca tcggggtccg gccgctgccc ccgtactcgg ccggccagcc
     1381 caccccgagg cggccgtccg cgccgaggcg gcggatcgtg gcgcggtaga agcgcttctg
     1441 ctcggccggg tcgtcgtggc gggcgtgggc gcggcctgcg accagcccgg cgaagtagtc
     1501 ccgcagctcg gcgcggaagc gccgctgttc cggggtgtac tcgaggtcca cggcccctcc
     1561 aggggtgctc gccgtatgcc gcgctgacgg cgcacaccgt agaacctgtt ccagaaattc
     1621 ggaaggcgga ggagaaacag ggacctcgcg gggcgtcagc cctgcgaggt ccctgcgagg
     1681 tccctgccgt tacggcgatc ggtagggcag tgggtacggc ggtcgtgccg cgcccgtcag
     1741 cgggcggcgt gccggcggtg gcgtcccccc gtgggcgtgc ccccgccccc gcccccgccg
     1801 cggcgacggc tgtgcggcac gggccgggtg tgaccgtggt ggccgccgtg ctgctccgcg
     1861 gcctccagct cggcgagctc ctggtccagg ccgaagcgct ccagcagcgg gatgcggtag
     1921 agccgcggga gcagccaggc gtgccagacg ccggtgacga agatgatcgc ggacgaggcg
     1981 atcaggaccg agccgagggt gtcggtcggg tagtgggcgc cgacgtacca gcgggagaag
     2041 gcgatgagca gcacggcgaa gacgccgacg acggctacgg tccgccggtg gcgggactcc
     2101 cggaagagga agtacgcggc gatgaacgcg gcgaccgtga aggcggtgtg accgctggga
     2161 aagctgttgg agccgatctc ggggtccagc atgaactccc gcggcggccg gggccgggcg
     2221 acgacggcct tcgcgatctg ggtgctgttc cagccgaccg cgacgacgag gaaggtggag
     2281 accgccgtca ccggccggcg ccgcacgaac agcagccagc cgcaccagac cgccaggatc
     2341 agcaggccgg cgaccgggga cgcgagggcg ctgaccccct ccatgaccac gttcagccac
     2401 tcggtgcgga aggtggtctg gaccgtacgg tccagcttca ggtcgtgcgg ctggatgaga
     2461 tcggtgtgca cggctaccag gcccagcgcg atcgcgacgg cgaacagcag gaccgagttg
     2521 cgcaaccagt ggcgcacgta cggcatgggt ggggcgtcct ttgtatcggt agggcggtac
     2581 cggcacggca gtacacgcga aggcgacgaa tgcctgccgc aggggtgacc acggcacggc
     2641 tgtacggcaa agctacacgc gccgcacgcg cacccttcgg ggacgcccgc cccggacgcc
     2701 gccggcggcc gcgcgacccg ggccgcccac caccggcggc gcaccctgcg tgagggagtt
     2761 atatccgacg gtgaccaccc ggccggaccc ggaggcgggg gtatgggcag cgattcagcc
     2821 gatcgtggac ggagcctcgg aggcccggga cggcgaacct tgacgccgcg gcgcggccgg
     2881 cggttcccgg gcgaggggat ttgtgccgtg tctcacgccg cgagcgccgc attccgctgg
     2941 ccggatcccg ctccccgccc acaaggccct tcaaccccac gcgacttgac ggtgtcctgt
     3001 ccggtgtcag cacaccgccg gagcagaggg gctacctgcc atgaacatac gcacccgcac
     3061 cgtccacaga gccctggcgg gggcactggc cgccgccgcg atggccgcgg cggccctcac
     3121 cgcccccgcc gcggcccggg ccgccggcac gacggccgca ggcggccggg aggccgccgc
     3181 gggccacgac cggcacgccg ccacccgcag cgccatggag gcccaggtgg cggccggcat
     3241 acccggcgtc ctggggcagg cccgggacga tcacggcacc tggcggggct ccgccggcat
     3301 cgccgaccgc accaccgagc ggccccgcct cgcccaggac cgcttccgca tcgccagtgt
     3361 cagcaaggtc ttcacctccg tcgtcctgct ccagctggag gcggagggcc ggatcggcct
     3421 ggacgacccc gtcgagcggt ggctgccggg cgtcgtccgg ggcggcgggc acgacggccg
     3481 ggagatcacc gtccggcagc tgctcaacca cacgagcggg atctacaact acaccgagga
     3541 cccgcgcttc cagaagctgc tcggccccga cttcctggag caccgcttcg acgaccacac
     3601 gccggacgag ctggtgaaga ccgcgatggc gcacgcaccg tacttccggc cgggcggggg
     3661 ctggcactac tccaacacca actacgtcct cgccggcatg gtcgtcgaga aggtgacggg
     3721 acgctcgtac gccaccgaga tcaagcggcg catcatccgg cccctggggc tcaccgccac
     3781 caccctcccc ggcacggcgc ccgaactgcc ggggccgcac ggccgggcct acagcacgct
     3841 gctggccgag cccgctcccg acccgaagat ctacgacgtc accgagctca atccgtcgtg
     3901 gggcggcgcc gccggcgaga tcatctccac caccggcgac ctcaaccgct tctacggcgc
     3961 cctcatcggc gggaagctgc tgccgagggc ccagcagcgg gagctgctca ccggggtatc
     4021 cgtggatgac cagatgcccg gcgtccgcta cggcctcggc gtctacacgg ccccgctgtc
     4081 gtgcggcgtg accgtctgga tgcacaccgg cggcgtccac ggctccgaaa cgatcgccag
     4141 tgccaccgcc gacggccggc acaccgccgc gttcaacttc aacggcgact ggacgggcga
     4201 cctcggcgcg ctggtcgagg cggaatactg cggcaaggcc ccgtcgggca agtccgccgt
     4261 cgccgggccg cagaagacga cgacgctgat ggcgccgcgc tgacacgccc gcgcacggtg
     4321 cgcctgcggc ccgcggctgg tgacagccgc gggccgcagg tccgtacggg agcgccgggg
     4381 atcagccctg gcagatcccg cgggcgtagt cgaaggtcgc cgtggcctgc gagtacttcc
     4441 actgcggggc cagcaggttc gcgtcgagct gctgggcggc ctgcgggctc tccaccatgt
     4501 acccgaagtc ctgcagccag gacgggtaga ggttcttcga gccgatgtag aaggccgagc
     4561 cgtccacgga caccagcttg tggtgctgtg cgtacggctt gccgtcggcc cacttggcgc
     4621 tgtccgagct gcgggcggtc gccagctgca ggttgccgca catggccgcc ttcgcaccct
     4681 gctgaccgcc ggtgagcggc gcgaggcggt tgcgcaggac gtcgctgatc tcgttcagcg
     4741 acttgatctg cgagtagccg ccgctgccga ccgcgccccg gttggccggg tcgctgacca
     4801 cgatgcgcac cttcacgccg gcggccagct tcgcggcgag cgcgtcgtag agccggatgt
     4861 cgtagcgcgg gagcggcggg caggtggcgt tgaggtcctg ctgggagatc tccacgtgac
     4921 tgcgcgcact ggccacgaga gcgcgcaggg cgctctcctc ggggttggcc gtgtcgtagt
     4981 cgcggtcggc gttggtgttg tcgtgcaggc ccacgacgca cttggtgtcg ggcgccgtcg
     5041 gcaggtccgg ccggaaggac gaggaggggt cggagtcctg gatgccgacg ccgaggccgc
     5101 cgacggcgat cacggggacg ttcccggtgg ccggggccgc gacggggttc gcgtccttct
     5161 ccatcgtcgg catgcaggcg gcgccgtcgg acgcggcgaa ccagacgctc gcgatgttgc
     5221 tcttgttccc gcaggtccag gtccacagct ggtccaggta ccggccggcg gacccggccg
     5281 cgggcccggt cagggcgagg tcgacgtcgg acaccgggtg ggtggtgtcg acgtagtcgc
     5341 ccttccagct gttgatgccg ccggtgatcg ccgactgccc gtccaccacg aggagcttgg
     5401 agtggttcca ggagaaggcg gtcttcgagg tggtcatcga ggcgacgttc agggtgacgc
     5461 tgccggcggc cttgccgagc ttgtcgcgca ggtcgtcgcg gtacttcgtg ggcagcacgt
     5521 tcatgtggta gaccggcgcg gccccgacca gaacgcggac cttcggcttg ttgccgttct
     5581 ccaccgactt cttcaggccc gcgacgatcg cgtcctggaa cgccccgtcg gggaagggcg
     5641 ccagggtgga tatgtcgacg gtgcgcgtgg cccgggagat gttctcggtc atcttggcga
     5701 gcagccgctt ggtgccgggg cgctcggcgc aagtggcgtc gccccagcag ccgggggtct
     5761 gcaggagcca gtcgccgggg tcaccggagg aggcgtccag ggtgttgccg gcggtgcgct
     5821 cccacacgcg cccttcgagg ccgggcgaga cctggcggag ggtctgctcg acggcgtcga
     5881 ggtgcggggt ggcggaggag tcggcgagcg ccggggccgc ggggagcgcg gcgagggcca
     5941 gggcggagac cgctgcggag acggcgggac gggttaaacg gcggagccgg aggcgagcca
     6001 atgtgcttcc ttgatcgggg gtacggaggt gaccgggaac gcgccgcgcg gcgaaacgcg
     6061 cacggcgatc cgcagcgccg gggaccggca ctgcggatga tcaccggggt gaagctacca
     6121 gttgcccgga acgttccgtt caggagccgc agctgctgcc gccgccgcag ctggaactcg
     6181 aactggagga ggagcagctg gagctggagc agctcgaatg gccggagtgg ctggagtggc
     6241 cggagtggct ggaacagctc gatgcgccgg agcagccgta cccgccgctg gtgtgggacg
     6301 acgaggagga agaggaagaa gacgaggaag aagaggactt cgcggtcttc cgggacggcg
     6361 gcttcttcgc gcccttggag tacgagcgca cgctgcccac gccggggctc ggcagtgccg
     6421 cctgcctcag ctgacccagg aacggctggt ccggctcggg cccgccggca ccgtgcaccg
     6481 cgacgacgcc cgcgatgccc tccgggtgcg tggcggagaa ccgggcgctc cagggaccgg
     6541 tcgccggagt ccgctcgatg aaggccttgc cgcgcggggt gggccgcacc ttcggcccgg
     6601 cagggcggca ccggacccgg agcacgatgc cggcgacgag gaggccgagg acgacgaagg
     6661 ccgtcacgaa gctcgcgggc atgaggacca gggccacgac gccgacgccg gtgaggacga
     6721 gcccggccac ctggacgtcc gcggcgcgct gccacttctg cttcaccacg ggcgacacca
     6781 gcatgccgcg ccggacgaga gcgccttcca gggcgtcgac ggccgggtcg aacttcagcg
     6841 aggtgcggac cctgcgcagg gagatgctcc agtcggcgcc gcagcggccc agcagggcgc
     6901 gctccacggc gttgtacgca gcggcccgct cgaccttgag cttgccgctc tcgttcacgg
     6961 atatccgccc gtcgtcgcac atgccggcga tgacggtgtc cacgacccgg ttgcggccgc
     7021 cgagcaggta cgcgacctcc agcagctccg gctcgccctg tgcgggcggc gggtcggcga
     7081 gggcgcggcg gcgggcgacg acgagccaag ccgaaggggc gacgagggca aggagggtca
     7141 ccaaggaggc gacgacgatg ccggcgatca tagggcggtt gcctttcggg tcacgcgcga
     7201 gcgcaaggtg tgccaggccg acgccaggcg ggccgggaac gcggcggggc cggcggacgg
     7261 cgccgcgcgc cgggcggccg tccacgccgc gaggcactcc cgccgcccgg gatcggtgag
     7321 ggtgccgtcg gtccggattc cgtcggtctt caggagcgcc tcggcgaagt cgagcgcgtc
     7381 ctggcggtag ccgtcgctca tcggacggcc gcgggcatag gcgaggaaca gccgccggaa
     7441 gtccgccccg aggatctcgg gcagctccgg cgcgaccttc gcgacgacgt ccgcgcgctt
     7501 gccgagcagc gcctgctgct gcacgcgcag acgttgcggg tcgaagccgg gcggcggggg
     7561 tgcgtccgcg acgagcgcgg agagcagggc gtgctgggcg tgcgcgaggc gccgccgggc
     7621 ggcttcgggg gcggtttcga gggcggtttc agacgccgtt tcaggtgtca tctcagacac
     7681 tgtgcgccac cgtccgctgc cggtcctgcc ggtcctgccg gtcctgccgg gaggagcgcc
     7741 gggcaccggc caccgtcgcc ctgatcgcgt ccagttccgc cgcgagctct tcgggcgcgg
     7801 ggaaggcgtc gtcgcgctcc aggaggacgc ccgggggcgt cacgcgggcg cacagctcgg
     7861 cgaggacgtc gaggacgggg ccggtcacgg ggtgggcgtg gctgtcgtgc cacaaaccgc
     7921 cctgctcgac gcctccggcc acatgcacgt aggcgatggc ttcgagcggc agttcatcca
     7981 gggaggccgc gggatcctgc cccaggttga cgtggttcgt gtggaggttg gcgacgtcga
     8041 tcaaaagccg cacgcccgtc ctggcgacca gctcggcgag gaactgcccc tcggtcagct
     8101 cctcgccggg ccacggcagg agggccgcga tgttctccag cgcgagcggg acgggcagca
     8161 tgtcctgcgc gatgcggacg ttctcgcaca ggacgtccag ggcgtcgcgg gtgcggggca
     8221 ccggcagcag gtggccggcc tcgatccgcg gggagccggt cagcggcccc ccggagcgga
     8281 cgaaggcgat gtgctcggag accagcggcg agccgagggc ttcggcgcgc tcggccagcg
     8341 cggcgagccg ggccagatcc ggccggtcgg cgccgccgag gccgagggag accccgtggg
     8401 ggatcaccgt cgtgccgcgc tcgcgcagct cccggagcgg gccggggaga tggcacgggc
     8461 agacgttctc cgcgacgacc tccacccagt cggcgcggac ccggcccgcc gccacggcgt
     8521 cggccgtctc cgggcgccag ccgatccccg ttcccagtga tttgagcgca ctcggctcac
     8581 tcatggcccc gcccccgtct ttcccgtgct cccccacgct cccccgtgga gtcgaacgcc
     8641 tgtaccagcc agctttcccc gcagcacact gtacaaatcc tgcggcgggg aaaaagcaac
     8701 cgcccccacg acgggttcgg tcccgtacat ctctcgtatg acccgtgccg tccacaccgg
     8761 acctcagatg tacggcaacg ccgcctcctg ggctgattac tcagggtggt tcaaggccat
     8821 agcttcttga tcaacggtag ggcgccccct gccctccctg agtgatcccg aagtgaggca
     8881 gaaccatgta cggcaaggca ttcgcccccg agtaccgggg ctccctggaa gacctctctg
     8941 tgaacgcctc gctcgaggaa gtgctgtcca aggcggtcga acaacggcgg cgcgcccaac
     9001 tggacggctc cgcactcgac atggcgcacg ccgagctggc cgtcgcggag gcgagccggc
     9061 ggctcggccg ggtggaggac gccgagcgtg cgtggaaggc gagctaccgg gccgcacggc
     9121 aggcggcgga cctgggggcg atggcctggg ccgtgtggag cggcggcacg ctcgcccggc
     9181 agcgcggaac cctggccctg gcccggcgct ggctcgccat cgccgccgaa ctcgccgagc
     9241 ggggcgacga catcgtggcc cgcggctact ccctcgcggg cctcgccgag accggccgca
     9301 tccagggcga ctaccaggcc gtcggcgaac tgcacgagaa gctgctggcc gaggcgcggc
     9361 gccggggcga ggcacggcac accgtgtggg cgctggaggg catcgcgcag atgcaccgca
     9421 actcgggctc gtacgacacc gcgctggcca tgttcgagga ggcggcggag atatcgggcc
     9481 gggcggacga cgcccgcggc cacgcgtggg cgctgcgcgg gatcgccgac gtgctgtccc
     9541 tgcgggggga gaccgagcgg gcgctcgcgc tgctgtcgga ggccgagggg acgtgccggc
     9601 ggatgaagct cgtcagcgcg ctggcctaca accacaagat gcgcggcaac gtcctgttcc
     9661 gggcgggccg ttacgcggag gccgaggagt gctaccgcgg ggcgctggag gagttccggg
     9721 agatggcgga gccgcggggt gccgccctgg cccggctcgg gctggtcaag agccgggccc
     9781 ggctggggca cgaccgcgcc gagaccgccg ccgagctgga cgacctgcac cgtacgctcg
     9841 gccggatcgg cctgctccac gcccggcgga tggtcgaggc ggcgcgcgcc gagctgggga
     9901 tgccggcgga gcctgcagct gccccggcgg ccccggctgc ccgccctgcc gcctgacagc
     9961 acgtccttcc gcggcagccc acgacaggag agagaagccc atgcccacgc aggccggccc
    10021 cgtgcccccg cagaccgcac tccggacccc cgctccccag acgctcgccc gcgcacgggc
    10081 gctggccgag cccgcgctca gagccgccgt ggcgacgctg cacccgctgc ctgcccgtat
    10141 ggcggccttc tcgttcggct ggtgcgaggc cgacggcacg ccgagcccct cccccggcgg
    10201 caagggcgtc cgccaggcgt tcgccctgct cggcgcggag acggtgggcg ctcccctcgg
    10261 gaccgcggtg caggcggcgg tggccgtgga gctggtgcac accttctcgc tggtgcacga
    10321 cgacatcatg gacggtgacg agcggcggcg gcaccgggac gcgacgtgga aggcgttcgg
    10381 caccggaccg gccgtcctga cgggcgacgc cctgttcgcg ctggccgtgc ggacggtcgc
    10441 ggaggccggg ggcgagcaca ccggccgggc ggtggcgcat ctggccgact gcctgggcga
    10501 gctggtgcgc gggcaggccg acgacctgct gttcgagaac cgcccgtgga cggggcgggg
    10561 agcggtcggg ataccggagt acgaggcgat ggcggcccgc aagaccggtg ccctgctcgg
    10621 ctgcgccctg tccctgggac cggtgctggc gggcgccccg cccctgcaga cgggtgccct
    10681 cgccgaggcc gggcggcggc tcggcacggc gttccagatc gtggacgacc tgctggggat
    10741 ctggggcgac ccgcggacga cgggcaagcc ggtccacggc gacctgctgc ggcggaagaa
    10801 gaccctgccg gtgctggcgg ccgtcgccct ggacgacggt gcgaccgccc gcgagctggc
    10861 ccggctgctg ggcccggaca cgcccccggc cgccgcggcc gcacgccgcg cggccggcct
    10921 ggtcgaggcg gccggcggcc gggagttcgc cctggaggag gcgcaccgcc atgcggcggc
    10981 cgcccacgac tgcctgcgcg gcgccggcct cgccgagggt gcggtcggtg aactcgtcgc
    11041 gctctccgca catttgctgg agcggcggct gtagcacctc tgctatggcg gctgcaacgg
    11101 cggcggatac cctcccgctg cgggttactt cgccgtcggc accggcagcg gcgcggcctt
    11161 gcaggtgacg tcccgggcgg gcagttctcc ggagaggagg tacttgttca cgatgccgtc
    11221 ggcgcaggcg ctgccgccca ggtagacgcc gtggtcgccg ccggtgtccg tgaccaggcg
    11281 cgagccgcgc aggtcccggt gggcccgctg cgcaccctcg tagtacgtgg ccgggtcgtg
    11341 cagggagttg agcatcagga cgggcggcag gcccttgccg gtgaccttga cgcgcggcgc
    11401 cggggaggcg ggccacgccg cgcacgcgga ggcgaaggcg agctctcggg cacccatcag
    11461 ggggtacttg gcggtgtcct cggcgctgcg gcggacccag gagccggtgt cgcggttcca
    11521 cggggtgtcg gcgcaggtca cggcgaggaa ctcggcgaag aagttggtgc cgaggtagga
    11581 gccgaagacg gtgtcgacga gcttccgctc ggcgggggac gccgtgtccc agtgctccag
    11641 cgcggcgagc gtcttcgcga ggcccgggaa gccctcctgc gagtcgtaga tcgcctggat
    11701 ggtgccgctg tcgaagcggt tggggtcgag ggtcctgccc ttgccttcgc ccgggctgat
    11761 cgggtggtcg cgcagtgcgc tgcggcgccg ctcccacgtg gccttcgcct cggccgcggt
    11821 gcggccgtag tggtaggtgg cgtcgttctt cgcgagccag ggcaggaagt cctgctcaaa
    11881 acggcgctgg aagctcttcg gctggccctt ctcgaagtcc tcccaggtgc cgccgaaggc
    11941 tatgttgctg tccaggacgg cgcgttcgac gcgctgcggg aagagcgtgg cgtagtacgc
    12001 gccgaccatg gtcgcgtagg aggccccgta gtaggagatc ttccgttcgc cgagcagggc
    12061 gcggaagagg tccatgtcgc gcacggtctg ctcggtggtg atgtacggaa ggaggtcccc
    12121 gtgcttctcg cggcaggcgt cggcgagctt gcgggagttg tccacgacgc gttgcacggc
    12181 ggcgggcgag cggtcgcgga agtcacccgc gaagaaggcg tcgagctcgt cctgggtctg
    12241 gcactgcagc ggcgtgctcc tgccgacgcc gcgctggtcg aagctgacga tgtcgtggac
    12301 ggcaccgatc gcgggcgcct gccgggcgac gccggccggc ctcagcagcc ccttgccgcc
    12361 gggtcccccc gcggccatca tcagcacccc gcgccggtgg gcggggtcgc tcgcccgcac
    12421 gcgggacacg gcgatcgtga ggtccttgcc ggtgtccggg gcgtgccagt cgcgcgggac
    12481 ggtcatctcc gcgcactcca tggtggccgg ctcggggcag ggctgccacg cgagcttctg
    12541 ggaggtgtac cgctcgggca cggtcacggc cgtggcaggg cgcggctgcg cggccgcgct
    12601 ctgctgcgca gcggctgttc ccgccgggag cattgcggcc gcgaccaccg cggcgagtgc
    12661 ggccgacacg gcggcgagtg cggagacggc cggtacggtc cgccgcgatt tcctgagctc
    12721 gaacatcgaa cctcctggtg cgtggtgacg gttcgatgct cccgggcggg gtggccgcga
    12781 tcgaccccgc tggtatccgt tccgggggtg gcactggtac cacccccggg tctcctgagg
    12841 gttggcgcta cttcttcagg atggtgactt cgggataggc cgcggacggc cggtcgagga
    12901 gcgggctcgg ggtgccgcgc aggtgccggt cgaggaacgc gttcacgtac gcacgggtga
    12961 gcgcggtcga gcgggtgccg tgcaggctgc cgtaggcgcc gtggacctgg tccggcggga
    13021 tctggccggg catcccgaac cggtccacga tccagggagc gtccgtgaac gtcaggtggc
    13081 cgccttcggg cacgtcgagc cagcgcttcc agcccgtcag ccgctgccag ttcttgtccc
    13141 agttctccgt gtttccggcc cgctgtgcgc cgaagagcag cacgggcttg ttcagcccgt
    13201 cggcgggcag gtcgctgggg aagttgccgt cgaggttgac ggcggcgtcc acgcgcttgt
    13261 cgccgcgcag ggcctccacc gcgctcgcgc ctccgatgga gtggccgacc acggcgatcc
    13321 ggctgcggtc gacggcgagc gggctgccgg gggcggtcag ccggtcgagg aggaaggaga
    13381 agtccttcgc ccggttccgt acgacggcgg ccatgtccgg cttcgcacag atctcacagg
    13441 tctcgatgcg cccgccgggg aactcgaccg gggcctcgta ggtgtggtcg accgcggcca
    13501 ccgcgtaccc gcgcgacgcg aggtcctcgc cgagcgtggt gagcgtcagc cggctcaacc
    13561 cgaagcctgg cgagaggacg accagcggcc ggggcttgcg ggccggctcg gcgcccaggg
    13621 tcgagttcgt gcgtacgccg gcgagatcct ccttgccaag gaccgccttg gacagctcct
    13681 tcgatacgta aggggcgttc cggtcgccct ggtgccgtgc cgggtaccag agcgagacca
    13741 tgagctgccg cttgccggcg gcgggcttcc aggggtcggg gcgcgaggtg tcgacgaggt
    13801 gcagggtctt cgtcccgacc ggctgcttgc ccgtgggcgc cgggacccgg gccggggtgc
    13861 cggacgccga cggctcgggg gcccgttcca ccgccgcggc cacggccggg atctggggcg
    13921 cggcgaaggc cgcgaggagc gcggcggcca cgaaggaccg ccgcgatgtc ttccgcgatt
    13981 tccacaacat gatcatcacg ttatacggcc gtgacactcc tgccatccgc ctcaggtcgg
    14041 aggtgatcaa cttcgcacgg ccggaccggg ccggtcagcg gaccgaggcg taggcgccga
    14101 gggcgatgtg cgcgaagttg cgcagggagt ccgtgccggg ggcgaagtag ccggtgtggc
    14161 cgtgggcacc gagcgtgggg acgatgcggg cgccgaaccc cggggaggtg gggtcggtgc
    14221 cgtggcccag gccgaagagg tcgacgttgg ggacgttgcc tatccagtcc gaggagttgc
    14281 gcgcggcggc ccagacgcgg gcaccggtgt gcagcccggc caccgagtcg gcgcgcatgc
    14341 cggggctgcc gagcgccacg aggtcggcgg cctcagtgcg gtcgacggac ggggcggcca
    14401 ggccgcagac caccgagccg tagctgtggc agaagacggc gggcggcggc gcggcgggag
    14461 aggcggcggc cgccgccagc ccggagagca ggcgctccag gcgcacggcc ccggcctgcg
    14521 cgaggcgccc ggtggcggcg tccacaccga ggcccacggg cgtggtgtag ccggcccagg
    14581 cgatgacggc ggtcggggtg ccgggcgccc tgcgctccat ctcggcccgc agggaggcgg
    14641 ccatcccggc gggggtgccg tagcggtcct tcgtccggtc gaaggtgcgg aggtcgatgt
    14701 ccgaacccgg cacgatgacg gcggtgtgcc gggcggccgc cagatcgccg tacacctcgg
    14761 cgacctggcc gcggccgcgc gggtcgaagg ccaggatccg gcggcccggc gcgagcagcc
    14821 gctcgcagcg gtcggcacgc tcgcgggcct cttcccgcgc ggcgcgggtc aggccggggt
    14881 ccgcgacccg ggcctgcgcc ttctcccgct cggcggctat cgcccgggcg ttggcctcgt
    14941 acctcagggg cacgggcgca ccgtcgaggt tgccgacgac cagcgcgtga cgggccgcca
    15001 ggtccttgcg ctgggcctcg gtgagaccgg cgaagaacgc ggcgaccgta cgcggtgccg
    15061 ccgtcgccgg gtccggcagc tcgcggtgga gggagtggtc cgcacgccac gcctcggcac
    15121 cggcgggcgg gccggtcacc acggcctgct cgtcgctgac ggcccagccg gccgtgccgg
    15181 ccacgaccgt ggcggccaga gctgcggcga ccagcgtgcg cttgaagcgg cccatgactg
    15241 tctctccctc gtcccgttgc gtgacagagg gaaagctaga aagagggtgt ccgagcctgc
    15301 gtcaccccag ggagccaacc ctggagtgat acctcagtag ggggtcggcg agggggcgcc
    15361 ttcagcccct cgcgggatcc tcggaatcca cggagtcctc gaagtcctcg tagtcgaagc
    15421 ccggtgcgac cacgcacgtc accagcaccg gctcgtcccc cgcaggctcg gccgactgcc
    15481 acacgccgcc gggcaccagg aactgcggtt gctcgccccg ctcgacgccg ggtccgacga
    15541 ccacttcgga ggcctccttc ccgtcgggcc tgtcgccgga gccgccgagc ctcatccgca
    15601 gcgggccgcc gcggtgccac agccacagct cgtcggagcg cacgcggtgc cagcgggaga
    15661 cctcaccggg gtggaggagg tagtagatgc cggtggcgaa cgcacgcggc ccgccgtagc
    15721 cgtcggggac cgcctcgcgc gaggtcttcc acgtctcgcg gaaccaccct ccctcgacgt
    15781 gcggttggag accgaggagc gcgaccagtt cggagatgcc ggaagtactg ccggaagtac
    15841 tgtcagccat ggcgtcattc tcgcgcggcc tcggccttga cggcatccga ggctatgacc
    15901 agggccgcgc cgatgacggc gaggacgatg ctcgcgtaca tctcgtagcc gtcgagaaaa
    15961 ccgaggtagc gcacgaccac ccagtagtgg aaccagccgg tgagtccgtg gacgacgccg
    16021 cccagcccct gcaggacgag gatgacgccg acgccttcga gcagcttctt catacccgcc
    16081 atgctcctgc cgccgccccg ccccggtcat cgcccggaag gctgtgcggc gccgaccgaa
    16141 gtagccgccc gcagtccccc ggatcatcca aggtcccgcc tcgtacaact ttggtatcgg
    16201 ccctccgtcc gatgcctccc gtccgcccgc cgcgtcggta aattggctgc tcatggacgt
    16261 gaagaccgag gagacggcgg aggtgcggcc ccgcagggcg cgcagtgtgc gcgactgggc
    16321 ggtggacatc ctctgcatcg ccctcgcggc cgtgatcggg atactggccg ccgaggcgct
    16381 gcgcaaggct ccggacccct cgcccgcact cctcttcttc gaccagatcg tgggcgccct
    16441 ggcctgcgtc gcgctgtgga tgcgccgccg gtggccggtg ccgctcgccg tggtcctggt
    16501 ggtggtgagc acccccgtgc cgcccgccgc aggggccatg ctggtggcgg tgttcacggt
    16561 cgccgtgcac cggccgttcc ggaccgtggc cgccgtggga gggctcgccc tgatcagcga
    16621 gccgctgcag gcggcgatcc gccccgaccc ggacctgccg ttccccgccg cgacggccac
    16681 gggcctgctg ctggtcctca ccgtcatcgg ctggggcatg ttcgtccgct cccggcgcca
    16741 gctggtcctg tcgctgcgcg agcgcgcccg gcgggccgag gcggaggcgc agctgcgagc
    16801 ggagcaggcc cagcgcctgg cgcgggagcg catcgcccgg gagatgcacg acgtcctcgc
    16861 gcaccggctg tcgcttctgt gcgtgcatgc gggggccctg gagttccgtc cggatgcacc
    16921 gcccgcggag gtggcccggg ccgccggggt gatccgtgac agtgcgcatc aggccctgga
    16981 ggatctgcgc gaggtgatcg gggtgctgcg agcccccggc gcggaggggg gaggggaccg
    17041 cccgcagccc accctggctg cgctggagga gctggtggag gagtcccggc aggcgggcac
    17101 ggaggtggtg ctcgtccagc gggtggccga cgccccggcg gttccggagg ccacgggccg
    17161 cacggtgtac cggatcgtgc aggaggcgct gaccaatgcc cgtaagcacg ccggaggtgc
    17221 ggcggtgagg gtcacggtcg agggctcccc ggaggcgggg ctcacggtcg ggatcaccaa
    17281 tccgccgggg gacggcagcg gagcatccgt gcccggctcc gggcaggggc tcatcgggct
    17341 ggccgagcgc gccgccctcg ccggcggccg gctctcgcac ggacccacac ccgacggcgg
    17401 cttccgcatc gacggctggc taccgtggcg gccatgaacg ccccgcagcc gccgcacggc
    17461 accgagccct cgcactcccc cggggcccag gcccagcagt ccccgcaagg ccggccgatc
    17521 cgggtcctgc tcgtggacga cgaccccctg gtgcgggcgg gcctgtcgtt catgctgggc
    17581 ggcctgcccg acatccgcat cgtcggagag gccgccgacg gttcggaggt caccgccctc
    17641 gtcgaccggc acgcgcccga cgtggtgctg atggacatcc gcatgccgtc ggtcgacggc
    17701 ctggccgcca cggaggagct gcgccgccgc gaagacgccc cggaggtcgt cgtcctgacg
    17761 accttccacg ccgacgagca ggtgctgcgg gccctgcgcg ccggagcggc gggcttcgtc
    17821 ctcaaggaca cccctccggc ggagatcgtc gcggccgtgc gcagggtcgc cgccggtgag
    17881 ccggtcctct cccccgccgt cacgcagcag ctcatcaccc gggtcacgga gcgggagcgg
    17941 gacacccgcg gcgaccgggc ccgggcgctg ctggccgcgc tcaatgaccg ggagcgggag
    18001 gtcgcggcct gcgtcgggcg cgggcagtcg aacgcggaga tcgccggcgc gctctatatg
    18061 agcgtggcga cggtcaaaac gcacgtctcg cgcatcctca ccaagctggg cctcaacaac
    18121 cgggtgcaga tcgccctgct cgtccatgac gcgggcgggc ccggcgcgga ggcctgagcc
    18181 cgccctgagc ccggcctgag cccggccgag gccgggcccc ggcacagcgc tgtgagcagc
    18241 tccccgagca gaccggaccg gcgctttcca taagccgctc cgctaccacc acgcgaccgt
    18301 cggtcacccc ggcacgcccg tagggcggtg ttgcgcaacc gcctacgaaa ctacatgcgg
    18361 ccgacgtacg gctgttacaa aacagcgggg aaacagcagg ttgccggtca taggatcgaa
    18421 ctcatgatcc atgggcgatt agttctaatc gcccctttgc ttttctatcc gcgcatcacg
    18481 cgcaggagag tgggggaaac ctgtgcctgg gcacataccg cgccgacgtg tactccaggt
    18541 cgcgggcggc ggcatcgtcg tcggagccgg cgcggtgggt gcctggcagt ggctgtcccc
    18601 ggaggcgaag aagaaggccg cgcaggacgg cgctccggta cgccctgcga aggccacgac
    18661 gtccgagtcg ttcgtccacg tcatcgccca ccccgacgac tccctctact tcatgaaccc
    18721 ggagctggag cagtcgatcc tcggcggcgg cccctccgtg acggtctgtc tcaccggcgg
    18781 cgagtccgac ggccgcaacg agctgtcggg cgcccgcggc tacaagcggc tgcccgagaa
    18841 gcggggcgag ttcgtccgcg cccggctcaa cggcttccgc gaggcaacgg cccagatggc
    18901 caccggcgac tggctcagcc cctggaccgt ggaggccctg tccctcctgc ccggcatcca
    18961 ggtcgagctg cacaccctgc gcgcggcccc ccaggtccag ctgatcttcc tggagctggt
    19021 cgaggcccgc accctgcgca atccgcgcaa ggagagcctg cgcggcctgt ggctcggggc
    19081 gaccccgcag ctgacgacgc tccggccggc cgccagcccg gtcaggagca ccttccagta
    19141 cggccgcaag cagctcatcg acaccctcgt cgcgatattc gagcgctacc agccgaccgt
    19201 cgtccgcacc ctggacccca accccacgca cctgccgaag ccgccggagt tcccgaacac
    19261 cccgcccgtc ctgcgcggca tagccaagta cgaccaccag gaccacacga cgtccgcgtt
    19321 cttcgcccag gccgcgctcg ccgagtactg gggccgcaag cacgcccggc ccacggccgt
    19381 ggacagctac gtcggctacg aggtctccca cctccccagc aatctcgaca aggccaccac
    19441 cgaccacaag ctcaagttcc tcgacaccta cggctgggcc gacggcaagg actgcggcga
    19501 cgccgcgggc tgcggcgacc gcaaggtggg ccgcacctcc gggacgaagt accacggctg
    19561 gtcgagcaac tgccgccacc gcgcgcccgg cacgatgcgc tgggtgcagc cgctgcccga
    19621 cggccgcctc gcggcgttcg cggtcctcga cggtgcggcg cagtgctgga ccgaggccaa
    19681 ggccggcagc ggcatctggt ccacgcccac ctccctcggc ggatcgatgc tggagggcca
    19741 ggtgcaggcg ctgcgccact ccgacggcac cctgcagctg ttctccatac gcacggtgct
    19801 acccgggaag gacacgccgc accggcgcga ggtcgtcacc gcgctgcaga gcggcgacgg
    19861 aagcggcgac ggctccggcg gcaccccgtc gttcggcccc tgggaatctc tgggctcgcc
    19921 cgagcaggac cccgcgcgct cgatggagat gggctatccg gtcgccgtgg ccggcaccga
    19981 cggcaccgtc cacgtcttcg tccgcacctt cgagggcgag gtgagccggc gcagtggcgc
    20041 cggcggcaag gacttctccg agtgggagac gctcccctcc gccggccccc gggtgaggct
    20101 cgaggacggg ctcgacgcgg ccctcgacgg ccagggccgg atccacctcg tggccgccga
    20161 cacgaagacc gtgcaccact ggatgtcgca gggtcccggc ggcccgctgc agccggccga
    20221 gccgacgaag ctccccgccg tcaccggccc gctgagcctc gcccccctcg cgagcggcgg
    20281 catgcgcatg gccgtgcgtc agccgaacac ctcccgggta ctcgtcgtcg accggctcgg
    20341 cgacgacaag ggctggcgcg tctcggccca gtgcgaccct ctcaacggcc atggccgcgt
    20401 cgccgtcgga caggccggga acaccaccgt gctcaccgac cacgacggca agggccgcgt
    20461 gcggctgtcc gccgggtccg gccgcccggg tccgtggggc aaggacggca ttccgtaccg
    20521 gggtgtcccc ggcgtcgcgc tcgacgccaa gggcaatgcg gtcgcggtcg tcgtcatggg
    20581 cctggacaac aagctgagca gcgcgcggct gcgcggcccg ggcaagggcg cgttcacgga
    20641 ctggatcgcc cacgacggga aggcgcggac gaacgtccag tcgtaggacg tcgtacgggt
    20701 cgtacggagg tgaggcgccc ggcgctcagg cgtccggcgc cggcgccccc ggtcgcgcgg
    20761 tatctcggcc tatcgcgcgt cgtcctcggc ctatcgcgcg atgtcctcgg cgaggatccg
    20821 ttcgacgttc cgctcggcca gcgccgtgat ggtcacgaac gggttcaccc cgatcgagcc
    20881 cgggatcagc gccccgtcgt tcacgtacag gtgccggtac ccggcgaccc gcccgtaggc
    20941 gtcggtggcc cggcccagga cgcagccgcc gagcgggtgg tagcagaagt cgtccccgaa
    21001 tgccttgggc cgcgggccga agaggtcgta gcggtagtcg gtgccgttcg ccttgttcat
    21061 ccggtcgaag aagg
//
