LOCUS       NZ_CP040272            22358 bp    DNA     circular CON 31-AUG-2024
DEFINITION  Nostoc sp. C052 chromosome, complete genome.
ACCESSION   NZ_CP040272
VERSION     NZ_CP040272.1
KEYWORDS    RefSeq.
SOURCE      Nostoc sp. C052
  ORGANISM  Nostoc sp. C052
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
            Nostoc.
REFERENCE   1  (bases 1 to 7828336)
  AUTHORS   Li,F.-W.
  TITLE     Complete genomes of symbiotic cyanobacteria from bryophytes provide
            new insights into the evolution of Vanadium-type nitrogenase
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7828336)
  AUTHORS   Li,F.-W.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2019) Boyce Thompson Institute, Boyce Thompson
            Institute, 533 Tower Rd, Ithaca, NY 14853, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.4.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 84.0x
            Sequencing Technology             :: Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013393905.1-RS_2024_08_31
            Annotation Date                   :: 08/31/2024 08:18:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,527
            CDSs (total)                      :: 8,409
            Genes (coding)                    :: 8,174
            CDSs (with protein)               :: 8,174
            Genes (RNA)                       :: 118
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 104
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 235
            CDSs (without protein)            :: 235
            Pseudo Genes (ambiguous residues) :: 0 of 235
            Pseudo Genes (frameshifted)       :: 84 of 235
            Pseudo Genes (incomplete)         :: 168 of 235
            Pseudo Genes (internal stop)      :: 38 of 235
            Pseudo Genes (multiple problems)  :: 50 of 235
            CRISPR Arrays                     :: 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:15:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6602842
            Orig. end                         :: 6625200
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040272.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Fay-Wei Li, Boyce Thompson
            Institute, 533 Tower Rd., Ithaca, NY 14853, USA.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22358
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="22"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22358
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22358
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12358](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12358
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    1048..1065
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.23"
                     /tool="antismash"
     gene            1216..2343
                     /locus_tag="FD723_RS27220"
                     /old_locus_tag="FD723_27140"
     CDS             1216..2343
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015114038.1"
                     /locus_tag="FD723_RS27220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_27140"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_179068150.1"
                     /transl_table=11
                     /translation="MAQIVMQNQRGITSFQPLDVELRNVFKFFNQEPAVNGIDLDVRQG
                     EFFSILGPSGCGKTTTLRLIAGFEIADAGKVLIQGQSMTNVPPYRRPVNTVFQSYALFN
                     HLNVWNNIAFGLRLKKIPKSKIESRVQEALKLVKMESLRSRFPNQLSGGQQQRVALARA
                     LVNRPTVVLLDEPLGALDLKLRKEMQVELSNLHKDLGLTFVMVTHDQEEALCLSDRIAV
                     MNQGKIEQVGTPSQIYERPCTSFVADFIGDTNLFSGEIVSVDSTNVQISTKTGLSIVIS
                     RTEDTPTELSQAVVVSVRPEKIQLSLYPPNLPANCFEGRLINVMYLGTHVNYVVELTNS
                     ISIHVLQPNTLGVLPDRDTPIYVWWAETDCLAICQ"
     gene            complement(2741..8563)
                     /locus_tag="FD723_RS27225"
                     /old_locus_tag="FD723_27145"
     CDS             complement(2741..8563)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012410134.1"
                     /locus_tag="FD723_RS27225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_27145"
                     /product="AAA family ATPase"
                     /protein_id="WP_179068151.1"
                     /sec_met_domain="Pkinase (E-value: 2.8e-35, bitscore:
                     120.5, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSHLVNIPGYKVSEELYNGSRTLVYRGYRETDSLPVVIKLLKNP
                     YPSFSELLSFRNQYTIAKNLNSPLIVQTYSLEPYQNGYALVMEDFGGISLKDWGVGGSV
                     ESLMEFLEIAIALCNTLDILYRERIIHKDIKPANILINPETKQVKLIDFSIASLLPRET
                     QTLMNPNVLEGTLSYISPEQTGRMNRGIDYRTDFYSLGVTFYELLTGVLPFQSNDPMEL
                     VHSHLAKIPPSLREVKSEEIPQILSDIVMKLMAKNAEDRYQSTFGLKFDLENCLHHLQV
                     DGIIKGFEIAQRDVCDRFIIPDKLYGRETEVETLLQAFERVSLGATEMMLVAGFSGIGK
                     TVVVNEIHKPIVKQRGYFIKGKYDQYQRNIPFSAFVQAFRDLMGQLLTESNVKIQQFKN
                     KILAALGENGQVIIEVIPELEKIIGQQPSVIELSGSAAQNRFNLLFQKFTQVFTSDKHP
                     LVIFLDDLQWADSASLMLMQLLMADTKHLFLIGAYRDNEVNPAHPLMLTLNDIQKTAAT
                     INTITLAPLSQEQVNQLVAETLKCTENLALPLSRLVLQKTQGNPFFAIQFLKALHHENL
                     IQFNFESGCWQCDIAQINEQSITDDIVAFMGLQLRKLSSSTQNILQLAACIGNQFDLTT
                     LAIVAEQLETETSADLWQALQEGLVIPISDLYKLYQGENNEKLASQNKSNNKQLAKYRF
                     SHDRVQQAAYSLISENQKQLTHLKIGQRLLNATPEQERDEKLFEIVNQLNQGVGLITTQ
                     TERYELAMLNFAAGQKAKSSTAYVAAMQYLNQGIELLTIESWQHCYEITLALHELAAEV
                     ACLSGDFELMEQLVDDVLHNAQHLLNTIKVYEVKILAYVAQSKQPEAIKIALTVLELFG
                     IVFPTQPSPAEINQSLQETQLLLNQKQLEELLKLPEMTDPEALAVIRILAAVTAAVYQA
                     VPPLLPMIVCKQVCLSIQQGNASVSTLAYAWYGVILCITGEIELGNQAGELALDLLAKS
                     RSQEFKASTINMVYPFVKPWKYPIQTSLVPLSEGYQSGLEMGALEYAAYCAYNYCSLSF
                     FLGKELTVLEKEMAAYSQALAQLKQEVAYNYLNIFYQSTLNLGSTSVSQSYLPWQFQGV
                     VYNEAKMLPLHQTANDLYAIGTLYVNKLILCHLFQEWDEAIVVADYAQQYLDGVAGCIM
                     VAIFHFYDSLTQLAILPDTCEEEQERLQQRVLVNQQKLKQWTSHAPMNFQHKYYLVEAE
                     KYRVYGQKTEAMELYDLAIQLAQKNQYLQEEALANELAAKFYLDWGREKVAQTYMQEAY
                     YCYARWGAKAKIEDLEKRYPRLLQPILQQRQIHFNPLETIAFSSGTSSSHRASTTTNTS
                     ISNALDFTSILKAAQTISSSLELNQLITSLTSIILENSGAKKAVLILPQDDIWQVRAIT
                     FINHEKIQTILESQLLDDCHYIPVKVINYVKNTQQTVVIDNCKTDIIGLIGEYMQRTQP
                     QSVLCTPIINQGRLVGIIYLENQLTQGVFTSDRLSVTNFLCTQAAIALENAQLYKHLQE
                     RDKFLSSIYEGVGCLIFVTDIRDNGRFEYTGWSKSCELTVGIPASEVLGKSPQEVMAPD
                     ESAAIEQKYLHCFQTGIPITYEECLTFNDDKIWFLTTLSPLKDETGKVYRVVGTTINIT
                     DRKQAEEAVIEKSQALGIVLEDLQQAQLQIVQSEKMSALGNLVAGVAHEMNNPLGFIAA
                     SLKQAKPTIADVVQHLKLYQQSLPNPSTEIIDHAEEIDLTYSLEDLPKSIDSMVMACDR
                     LKNISTSLRTFSRADKDYKVPFNIHEGIDSTILILKHRLKANEQRPAIEVITEYGNLPK
                     VECFPGQLNQVFMNIIANAIDALDESNTGRSFAEIKENPHQITIKTSLEDHQVEIKIAD
                     NANGMNEEVKAKIFDHLFTTKSVGKGTGLGLAIARQIIVEKHSGSIQCNSSPGQGTEFV
                     IAIPVRQ"
     misc_feature    complement(9530..9545)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.56"
                     /tool="antismash"
     gene            10001..12358
                     /locus_tag="FD723_RS27230"
                     /old_locus_tag="FD723_27150"
     CDS             10001..12358
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015209723.1"
                     /locus_tag="FD723_RS27230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_27150"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_179068152.1"
                     /sec_met_domain="T1TS (E-value: 3.4e-76, bitscore: 255.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSKQPFELPSFYVPWPARLNPNLEAARVHSKAWAYEMGILGGA
                     EGSEDYGIWDERKFDAHDYALLCSYTHPDADEQMLNLVTDWYVWVFFFDDHFLELYKRT
                     QDMAGAKKYLNGLPAFMPVQPQETPPEPTNAVELGLVDLWNRTIPNASQDWVIRFSEST
                     INLLKESQWELANISQHRVANPIEYIEMRRKVGGAPWSANLVEHAVGSEIPAAIAPSRP
                     MRVLKDTFSDGVHLRNDIFSYQREVEEEGENANCILVLEKFLDVSTQEAANLTNDLLTS
                     RVQQFENTFVTELPSLFEEYSLTPDERLKVVLYAKGLQDWQSGGHEWHMRSSRYMNQTS
                     DKSSPASWFLGGPTGLGTSAARLGALYDSLGLKRFKSFTHVPYQPVGPVTLPQFYMPFS
                     TSLNPHLDDARRHSKEWARQMGMLDRLPGMPSIYIWDDHKFDVADVALCGAYIHPNGSS
                     AELNITACWLVWGTYADDYFPALYGYSRNMAGAKIFNARLSAFMPLDESPVPEATNPVE
                     QGLADIWARTAGPMNPNARRQFRRAIEDMTESWLWELANQIQNRIPDPIDYVEMRRKTF
                     GSDLTMSLSRLSQGDEIPPEIFRTRTMQNIDNSAADFACLTNDVFSYQKEIEFEGEINN
                     GVLAVQNFLNCDIPHAVAIVNDLMTSRALQFEHIVATELPALCDDFGLDTSTRKKLYGY
                     IKKLEQWMCGVLKWHRAVDRYKEFELRNNSTEKRLLQGPTGLGTAAIQIRPRVGQETTQ
                     TNVQPVVQNLLSSPTGLGTSATKIGSLLGKKG"
     misc_feature    complement(10029..10045)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.99"
                     /tool="antismash"
     gene            12432..13841
                     /locus_tag="FD723_RS27235"
                     /old_locus_tag="FD723_27155"
     CDS             12432..13841
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007358456.1"
                     /locus_tag="FD723_RS27235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_27155"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_179068153.1"
                     /transl_table=11
                     /translation="MTNAANTSLENQIEQQPISLGTEAARNLATTTKTQPQMQGITSRW
                     LLKLLPWVETVGGSYRVNRRLTYTVGDGRVSFTNTGSQIQVIPQELGELPLFRGFEDVG
                     VLNALASQFVQQEFAAGDVIIQAGQAADQVLLIAHGKVNKIGPGKYDDQVVLAVLADGD
                     HFGDYALVESQDIWDVTLTAITRCTILSLPQAAFQNLVNQSEALQAQVDRFREKLRQPQ
                     NQYGEASIDITSGHLAEALLPGTFADYEINPREYELSVAQTVLQINTRVADLYNEPMNQ
                     TEEQLRLTIEALRERQEHEMVNNRNFGLLHNADLKQRIFTRSGPPTPDDLDELISIVWK
                     EPSFFLAHPRTIAAFGRECNRLGLYPDPIPTGNSAIPSWRGIPIYPCNKIPVTKERTSS
                     IILMRVGATNQGVIGLHKTGIPDEYQPSLSVRFMGINEKAVISYLVSAYYSTAILVPDA
                     LGILEDIEIGL"
     misc_feature    complement(13957..13970)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.41"
                     /tool="antismash"
     gene            14032..15441
                     /locus_tag="FD723_RS27240"
                     /old_locus_tag="FD723_27160"
     CDS             14032..15441
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015209721.1"
                     /locus_tag="FD723_RS27240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_27160"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_179068154.1"
                     /transl_table=11
                     /translation="MTDALIRPNLDQENRQLQMSLSTKGARNLAKTTKTPPQMQGITPR
                     WLLQMLPWVQVTGGAYRVNRRLTYDVGNGRVSFTNTGTQVRVIPQALCELSLLRGFEDI
                     EVLNALADRFVQQEFASGEVIVQEGQPADQVLLIAHGKVNKLKAGKYETEALRDILAEG
                     DCFGGEAIVLSQETWEVSLRAITRCIVLSLPIQAFRELLNQSEALQTQVDRLRAILSKP
                     QDRHNQAEIAVSAGHSQETELPRTFVDYDLSPREYELSVAQTILQVNTRVADLYNEPMN
                     QTEQQLRLTIEALRERQEYEMLNNPGFGLLHNADLKQRIFTRTGPPTPDDFDELLSRRR
                     KSHFFLAHPRAIAAFNRECNRRGIYSPSKEVNGKIVPAWRNYPIFPCNKIPITKEGTTS
                     ILIFRVGEENQGVIGLHKTGIPDEYQPSLSVRFLGINEKAIISYLVSAYYSAAILIPDA
                     LGILEDVEIGH"
     gene            complement(15754..17136)
                     /gene="nifN"
                     /locus_tag="FD723_RS27245"
                     /old_locus_tag="FD723_27165"
     CDS             complement(15754..17136)
                     /GO_process="GO:0009399 - nitrogen fixation [Evidence IEA]"
                     /GO_process="GO:0065003 - protein-containing complex
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /gene="nifN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012412141.1"
                     /locus_tag="FD723_RS27245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_27165"
                     /product="nitrogenase iron-molybdenum cofactor biosynthesis
                     protein NifN"
                     /protein_id="WP_218651761.1"
                     /transl_table=11
                     /translation="MSDERIRQIAFYGKGGIGKSTTSQNTLAAMAEVGKRILIVGCDPK
                     ADSTRLILHCKAQTTVLHLAAERGAVEDIELEEVVITGFRDIRCVESGGPEPGVGCAGR
                     GIITAINFLEENGAYSDVDFVSYDVLGDDDMGRFVKEIRHRHPELDYLPIVLVSTPDFK
                     GTLQDGFAGAVESIVREIPQKSSKQDASPTQITILASSAFTPGDVQEIKEIVTSFGLIP
                     IVVPDLSSSLDGHIEDSSSAITANGTNTAQLRSIGSSVFTLALGDSMRGAAQILEQRFN
                     IPYEVFSELTGLVAVDKFLKALADISGVSVPQKYRRQRRQLQYMMLENHFYFGCKRVSL
                     ALEPDLLWSTVAFLRSLGVEIHSAVTTTRFPLLEKLPIKSVTIGDLEDFEQLAIGSDLL
                     ITNSHGVAIAQRLKIPLYRQGIPIFDRLDHGQFTKVGYRGTIQLLFDIGNLFLEQEIKV
                     KH"
     gene            complement(17126..17308)
                     /locus_tag="FD723_RS27255"
                     /old_locus_tag="FD723_27170"
     CDS             complement(17126..17308)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FD723_RS27255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FD723_27170"
                     /product="hypothetical protein"
                     /protein_id="WP_179068155.1"
                     /transl_table=11
                     /translation="MFWIQTLFAVERAPPTTFYIKLLLSSYSKQVPLVGTSLCDRLINL
                     QTHQTNNCRINYHVR"
     gene            complement(17632..18765)
                     /locus_tag="FD723_RS27260"
                     /old_locus_tag="FD723_27175"
     CDS             complement(17632..18765)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012412138.1"
                     /locus_tag="FD723_RS27260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_27175"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_179068156.1"
                     /transl_table=11
                     /translation="MKQDSDLRNNLKSIRTRLGMSQQDLANIASVTRQTISGVESGLYA
                     PSVAITLRLAKALGCQVEDLFWLERDLPEIEAVLAKPVPNGQQLRVSMARVGGQWIAYP
                     LIGKDAFRQDMIPADGESTSVAGTNKVRVRLLDDNLETLHNTVVIAGCAPVISLWARAT
                     ERWHPQLRVQYNFANSMAALHSLCTGEAHIAGMHLYDPETGEYNTPFVRDVLAGREAVL
                     ITLGVWEEGLLLKSGNPMGIRTVTDLVAGGATIVNREIGSGSRMLLEQTLQKEQIPFDT
                     VQGFDNVLKSHQDVAQAVVQGSADAGMSTASVATAFGLGFIPLHQSRYDLVILKEYLEE
                     APVQQLLSTLGHRMVHSQFEILGGYDISKIGEVVATV"
     gene            19204..19674
                     /locus_tag="FD723_RS27265"
                     /old_locus_tag="FD723_27180"
     CDS             19204..19674
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015126492.1"
                     /locus_tag="FD723_RS27265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_27180"
                     /product="hypothetical protein"
                     /protein_id="WP_256874939.1"
                     /transl_table=11
                     /translation="MQIASAKNCCFKFLHNQLGIDQSIQQMANKGMEKVMITEEDLAQQ
                     FNLIIEHTHPQVWKLLSQCYVKVIVPHPHLTRVNIKTCIRHAKYIGIYCPDRLISGVLE
                     QKKLLKEVAEYLGLVEVVCLNANHLMRDPLSNLKQTYPQLWLDLLWIVTQEK"
     gene            19774..20340
                     /locus_tag="FD723_RS27270"
                     /old_locus_tag="FD723_27185"
     CDS             19774..20340
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FD723_RS27270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FD723_27185"
                     /product="hypothetical protein"
                     /protein_id="WP_306296996.1"
                     /transl_table=11
                     /translation="MNQPCLHPDDLPSPQTIKLSGILFRQLEEATKKNFFLACDRMTRI
                     LLSSCHWYFQIIFEACQNIMNQPCLHPDDLPSPQTIKLSGILFRQLEEATKKNFFLAGD
                     RMTRILLSSCHWYFQINSGVLTLIVICNNMKSYRQIMKTVPQFAGHLKQFANRAKITVS
                     SPVDKGIPWVLNIDNSLPEGDLPNT"
     misc_feature    20834..20852
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.24"
                     /tool="antismash"
     misc_feature    complement(21393..21407)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 22.14"
                     /tool="antismash"
     misc_feature    21975..21984
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.44"
                     /tool="antismash"
ORIGIN
        1 tttttcggct gccttttgca catctaaatc gatggttagg tgcaaatcgt taccagcttt
       61 tgcctgtttc tcgccaataa cccggattgg tctaccagca ccatctactt ccacctgctg
      121 accgccccat tcgccccgta gagctttctc ataagctttt tctacgccca tctgaccaat
      181 tacatctcct agtcggtagc cttgctcctt tttgtccttt aactggtcgg cagtcaactc
      241 tcgcgtataa cctagtacat gcgccaattc cttgccgtgg ggataataac gcaccgagtc
      301 tgtattaatt tccacttccg ggagttcatt cttatactcc tttaatgccg tgatttctgc
      361 ttcatttaga tcgcgagcaa cccggatgag tgaagaagaa ttagcacctg cttgttctaa
      421 tttcttttcc atctcatctt gcggaatgtt gagaatttgc gctaaacgcg ggccgactac
      481 agaccaggaa ggtttagtat gtgccatcgg ccacaaatat acagagctag gatagcgagt
      541 actggctaaa agtttgccat tccggtcaaa aatattgccc cgttcaggtt gtttggcaat
      601 catccgaatt cggtttgctt cggctctttc ccggagtttt ggcccttcaa cgatttgcaa
      661 atatgccaaa cgcgccccaa tcccagccat cattaatagg gtaaatagga ttaaaaatat
      721 tgattggaaa ccacgtccaa ctgtacgggt atcttttttg ctgccaagtg atgggaataa
      781 agacataagt atcaattaca aaattcaaaa tttaaaatga ataaacgcaa ttttagcgag
      841 ccttttagaa attgttaata tgcagtttta atgcttaggg acttccaaat aaaaaatatt
      901 caattaactc ttgtggggtg ggcattttgc ccgccctatg gactaggcgg gcaagatgcc
      961 caccccacaa tattggatat gctccaactg agcctcctgc ctccttcaat agcttcatca
     1021 aagaatatct aagtactagc acgagtatat acaattaagc tgatactttg atactgagga
     1081 tgaaataatc cgacgagtat attcttaaac aattgttttt ggcggataca atgaaccaag
     1141 gtgtcaaatc tagtctgccc aatagactac ataaagtgac aaaataacgt aaatcacggc
     1201 attctactga agattatggc tcaaattgtc atgcagaatc agagggggat aacaagtttt
     1261 cagccacttg atgttgaact gcgtaacgtc ttcaagtttt ttaaccaaga accagcagta
     1321 aatggaatcg acttggatgt tagacaagga gaatttttta gtattttagg cccctccggt
     1381 tgtggtaaaa caacaacact gcgcttaatt gctgggtttg aaatcgctga cgctggtaag
     1441 gtgctgattc agggtcagtc tatgactaat gtgccgcctt accgccgacc cgtcaatact
     1501 gtatttcaaa gttacgcttt atttaaccac ctaaatgtct ggaataacat cgcttttgga
     1561 ttgcggttaa aaaaaatacc caaatcgaaa attgaatcta gagtccaaga ggctttaaaa
     1621 ctcgtgaaaa tggaaagttt gcgatcgcgc tttcccaatc aactttctgg tggtcaacag
     1681 cagcgagttg ctttagccag ggctttagtt aaccgtccca ccgttgtatt gttagatgaa
     1741 cctttagggg cgttagattt aaagctacgt aaagaaatgc aggttgagtt atcaaattta
     1801 cataaagact tgggattgac ttttgtaatg gtgacacacg accaagaaga agcattatgt
     1861 ttgagcgatc gcattgctgt gatgaatcag ggcaaaattg aacaagttgg tactcccagc
     1921 caaatttacg aacgtccctg cacgtctttt gtggctgatt ttattggcga tactaattta
     1981 ttcagtggtg aaattgtctc ggtagactcc accaatgtgc aaatttcgac aaaaacagga
     2041 ctctcaattg tcattagccg cactgaagat acaccaaccg aattatcaca agctgtagtc
     2101 gtgagtgtgc gtccagaaaa aatacagctt tcgctttatc caccaaactt gccagctaac
     2161 tgctttgaag gacggctgat caacgttatg tatttgggta cacacgttaa ttatgttgtg
     2221 gaattaacaa atagcattag cattcatgtg ttgcaaccga atactttggg cgttttacca
     2281 gaccgcgata cacctattta tgtctggtgg gcagaaaccg attgtttagc aatttgtcaa
     2341 tagtcaaaca attttggatt ttagatttta gattgaccgg agatttattc tacgtagatt
     2401 ctatgagtgt acttccaata cggttaaggt tttttggtga aaattctaga tcgcaaagat
     2461 gcgatgaatc accgtctcta caataatcag tctttggtag agacggcgat ttatcgaaca
     2521 gaattcagga gtcagaattc attctgaatt ctgtatgact ggcggatagc gtagcataaa
     2581 gccaactctt ggaggcatgg cttctcttct cctttggaga cgctaacgcg aacaagaatc
     2641 cgcgtactct tacagagaag caagctacgc gcagcgtctc gtagagagag cgtcttgatt
     2701 ctgacttctg acttctgaat tcttcttcac ctagcaatct tcattgccgg actggaattg
     2761 caattacaaa ctctgtacct tgtcctggag atgaattgca ttgtatcgaa ccactgtgtt
     2821 tttctacgat aatttgccga gcgatcgcca accccaaccc cgtccctttg cccacagatt
     2881 tcgtagtaaa taaatggtca aatatctttg ctttgacttc ttcattcatg ccattagcgt
     2941 tatcagcaat ttttatttca acctgatgat cttccaatga agttttgatt gtaatctggt
     3001 gaggattttc tttaatttct gcaaaactcc gcccagtgtt agactcatct aaagcatcaa
     3061 tagcattggc gataatgttc ataaatactt gatttagttg tccaggaaaa cattcaactt
     3121 taggtaaatt accatattca gttatcactt caattgctgg acgttgttca tttgctttga
     3181 ggcgatgctt gagaattaaa attgtactat caataccttc atgaatgttg aatggcactt
     3241 tgtaatcttt atctgcacgg gagaaagttc ttaaactagt gctgatgttt ttgaggcgat
     3301 cgcacgccat taccattgaa tcaattgact tgggtaaatc ttctaaacta taagttaagt
     3361 caatttcttc tgcatgatca ataatttcag tactcggatt gggtagactt tgttgataaa
     3421 gtttcaagtg ttgaacaaca tcagcaatag ttggtttagc ttgtttgaga ctcgcagcaa
     3481 taaagcccaa aggattgttc atttcatggg cgacgccagc tactaaatta cccagtgcag
     3541 acattttctc actttgaaca atttgtaatt gcgcttgttg taaatcttct aatactattc
     3601 cgagtgcttg agatttttct attactgctt cttcagcttg tttgcgatcc gtaatattaa
     3661 tagttgtccc gactacgcga taaacttttc ccgtctcatc ttttaaggga ctgagtgtgg
     3721 ttaagaacca aattttatcg tcattaaatg ttagacattc ttcataggta atgggtattc
     3781 cagtttggaa acaatgcaga tatttttgct cgattgctgc actttcatca ggagccatta
     3841 cttcttgcgg acttttaccc agcacttccg aagcaggtat accaaccgtt agttcgcacg
     3901 atttactcca tccggtgtac tcaaacctac cattatctcg gatgtcagtc acaaagatga
     3961 gacagccaac accttcgtaa atactactga ggaacttgtc tcgctcttgg agatgcttat
     4021 ataattgggc attttctaaa gcgatcgcag cttgagtgca aaggaaattg gtcacagaaa
     4081 ggcgatcgct agtaaatacc ccttgagtca gttgattttc tagataaata atccctacca
     4141 aacgcccttg attgataatc ggggtacata atacactctg gggttgtgtt cgctgcatgt
     4201 attccccaat caacccaata atatctgttt tgcaattgtc tataacaact gtttgttgag
     4261 tatttttgac gtaattaatt acttttacgg gaatataatg acaatcatcg agtaattgag
     4321 attccagaat ggtttgtatt ttctcatgat tgataaaggt aattgcccta acttgccaaa
     4381 tatcatcttg gggaagaatt aacacagctt ttttcgcacc ggagttttct aggataatgc
     4441 tagtcaagct ggtaatgagt tgatttaatt ctagagaact ggagatagtt tgagcggctt
     4501 tgaggattga ggtaaaatct agggcattag aaatactggt gttcgtagta gtagaagcgc
     4561 gatgagatga ggaagtgcca gaagaaaaag cgatagtttc tagaggattg aaatgaattt
     4621 gtcgctgttg cagaattggt tgcagtagtc gaggatagcg cttttctaag tcttctattt
     4681 tggcttttgc accccaacga gcatagcaat agtatgcttc ctgcatatat gtttgggcga
     4741 ctttttctct accccagtcg agatagaact tggcggcgag ttcgttagcg agggcttctt
     4801 cttggagata ttggtttttt tgagccagtt gaatagcaag atcgtaaagt tccattgcct
     4861 ctgtcttctg tccgtaaacg cgatattttt cggcttcgac taaataatat ttatgctgga
     4921 agttcatggg agcatgagat gtccattgtt tcagtttttg ctgatttaca aggactcgct
     4981 gctgcaatct ttcttgttcc tcttcacaag tatcgggtaa gatagctagc tgggttagtg
     5041 aatcataaaa atgaaaaatt gctaccatga tacagccagc taccccatct aaatattgtt
     5101 gagcatagtc tgccactaca atagcttcat cccattcttg gaacagatgg caaaggatca
     5161 atttattgac atacagcgta ccaatggcgt aaagatcgtt agccgtttgg tgcaaaggca
     5221 gcattttggc ttcattataa accacgcctt gaaattgcca aggtagataa ctttgactaa
     5281 ctgaagttga ccctaaattc aaagtagatt gatagaaaat attcagataa ttgtaagcaa
     5341 cttcctgctt cagttgagct aaagcttgac tataagctgc catttctttt tctaaaacag
     5401 ttagttcttt gcctaagaaa aaggatagag aacaataatt ataagcacag taagcggcat
     5461 attctaaagc acccatttcc aaaccactct gatatccttc cgagagagga acaagagatg
     5521 tttgaatggg atatttccac ggtttcacaa atggatacac catgttaatc gtgctagctt
     5581 taaattcctg actccgcgat tttgcgagga gatccaatgc caattcacct gcctgatttc
     5641 ctaactcaat ttctcctgtg atacaaagaa tcacgccata ccaagcgtaa gccagtgtgg
     5701 atacagacgc attgccttgt tgaatcgata agcaaacctg tttacacact atcattggca
     5761 acagaggcgg aactgcttga tagactgctg ctgtcactgc tgccagaatt cggatgactg
     5821 ctagggcttc aggatcggtc atttcaggca atttcagcaa ttcttctaac tgcttttggt
     5881 tcagaagtaa ctgagtttct tgtaaacttt gattaatctc tgctgggcta ggctgggttg
     5941 gaaacacaat tccaaataat tccagaactg tgagggcaat tttaatagct tcgggttgtt
     6001 tgctctgcgc cacataggcc agaattttta cttcatagac tttaatagtg tttagtaagt
     6061 gttgagcatt gtgcaacaca tcatctacaa gttgctccat taactcaaaa tcaccgctca
     6121 gacaagcaac ttcggcagct aactcatgta aagctaaagt tatttcataa caatgctgcc
     6181 aactttctat agttagcagt tcaatgcctt gatttaaata ctgcatcgcg gctacataag
     6241 cagttgaaga ttttgccttt tgtccagccg caaaattgag cattgctagt tcgtagcgct
     6301 cagtttgagt agtaattaat ccgactccct gattcaactg gttaacaatt tcaaacagtt
     6361 tttcgtctcg ctcctgttcg ggtgtggcat taagtaacct ttgtccaatt ttgaggtgcg
     6421 tcagttgttt ttggttttca gaaataagag aataggcagc ttgttgtact cgatcgtgcg
     6481 aaaatctata tttagctaat tgtttattgt tacttttatt ttgactcgct aatttctcat
     6541 tattttcccc ttgataaagc ttataaagat cgctaattgg tataaccaac ccttcttgta
     6601 aagcttgcca taaatcagca gatgtctcgg tttcgagttg ttcggcaaca atagctaaag
     6661 ttgtcaaatc aaactgattg ccaatacaag ctgctaactg caagatattt tgagtagatg
     6721 acgataattt tcgtaattgc aaacccataa aggcaacaat atcatctgta atcgattgtt
     6781 cattaatttg ggcaatatca cactgccaac acccagattc aaagttaaat tgaatgagat
     6841 tctcgtgatg caatgccttg agaaactgga tagcgaaaaa tggattacct tgagttttct
     6901 gcaataccaa tcgagaaaga ggtaatgcca agttttctgt acacttaagt gtctcagcaa
     6961 ctaattgatt tacttgctct tgactaagtg gtgctaaagt aattgtatta atcgtagctg
     7021 ctgttttttg gatatcattc aaagtcaaca tcaatggatg tgctggatta acttcattat
     7081 cacgataagc accaattaag aatagatgct tggtatcagc cattaataac tgcattaaca
     7141 tcaacgatgc cgaatcagcc cattgtaaat catctaaaaa tatgactaat ggatgtttgt
     7201 cactagtgaa gacttgagta aatttctgga ataataaatt aaatcgattt tgtgctgcac
     7261 ttcctgataa ttctataacg gagggttgtt gaccaataat tttttctaat tcggggatga
     7321 cttcaataat tacttgtcca ttctcaccta gagccgctaa aatcttattt ttaaattgtt
     7381 gaattttaac attgctttct gttaataatt gccccattaa atctcggaat gcttgcacaa
     7441 atgcactgaa gggaatattc cgttgatatt ggtcatattt acctttaata aaataaccgc
     7501 gttgtttgac aattggttta tgaatttcgt taacgacaac tgttttacca atacccgaaa
     7561 aaccggctac cagcatcatt tctgttgcac caaggctaac tctttcaaat gcttgcagta
     7621 gtgtttctac ttctgtttct cgtccataaa gtttgtcggg gatgatgaag cgatcgcaca
     7681 catccctctg ggcaatttca aagcctttaa ttataccatc aacttgtaga tgatgtaaac
     7741 aattttctaa atcaaacttc agtccaaatg tactttgata tctatcttcg gcatttttcg
     7801 ccatcaattt catcacgata tctgacaaga tttgcggaat ctcttcactt ttgacttccc
     7861 gaagagatgg tggtatcttc gctaaatgag aatgtaccaa ttccatcggg tcgtttgatt
     7921 gaaacggtaa aactccggtc agtaactcgt agaatgtcac acccaatgaa tagaagtcag
     7981 tacggtagtc aattccgcga ttcattctgc ctgtttgttc aggggaaata taactaagtg
     8041 ttccttctaa cacattggga ttcatcaatg tttgagtttc ccgtggtagc aaagatgcaa
     8101 tactaaagtc aattaattta acttgtttgg tttcgggatt aattaaaata ttcgcaggtt
     8161 tgatatcttt atgaataatc cgctctcgat acaatatatc taaggtattg catagtgcga
     8221 tcgctatctc taaaaactcc atcagagatt ctacgcttcc ccccactccc caatccttga
     8281 gagaaatccc cccaaagtct tccatcacca aggcatagcc attctgatag ggttccaggc
     8341 tataagtttg gacgattagc ggtgagttga gatttttagc tatagtatac tgattgcgaa
     8401 acgacaagag ttcactgaaa ctcggataag gatttttcag tagtttaatg actacaggta
     8461 atgagtcggt ttctcgatac cctcgataaa ctagagttct ggaaccattg tagagttctt
     8521 cacttacctt gtatccggga atattcacaa gatgactaac catactgcta aatctttaag
     8581 acttccagat ttagtgttcc cagaatatat aaggttattg ataaacaagg gacagcgaga
     8641 cgctacgcga tcacagcagg caatacttgt cggttaacgg gaaaagcgga atgggaaagg
     8701 ggaaagaaaa aacctttacc ctttaacctt ttcccaaaac caaattccag tttaaaatca
     8761 acaaagcgag cagtattgac atggcaggtt attccagttg agataatgcc tcaattaccc
     8821 agcgatcgcc tctggatatt tcttcgctag ttcctacaaa caggtgtagg tacgaaatat
     8881 atagggtttc gaggtttaga accaaaaaca agcgatcgtt tcagtaacga ttttccttgc
     8941 ttgtaggctc ggtttgccgg aggattggct ctatttctga ttacctgcaa tgttctgtag
     9001 tgactaccat cgcattgcaa tacttgtcgg ttaaggggaa aaggggaagg ggaaagggga
     9061 aagaaaaaat ctttaacctt taccctttaa ccttttcccc aaacctaatg ccgagttaaa
     9121 aatgcagaaa gcgagcagta ttgcatcgca ttgctctgtt cctggatttc tcacaagtga
     9181 aaaatccaag gggtctggga ggtgtgggag gatggggaag aagtcttacc cccacactcc
     9241 tctttcccta aagcctacac tatgcgtgag aaatccgggt gttgggaact gatatattac
     9301 ttattatttt tttatatatt ttaattattc aattaactgt ctacttaatt attttcttaa
     9361 ctgtcttaac tgtcttaact gtctacttaa ttattttctt aactgtctta actgtcttaa
     9421 ctgtctactt aattattttc ttaactgtct taactatcca gttaatgata actaaacgtc
     9481 ttaaactgtt attgcatttt attgataaag ctgagattat cttaaagaca gatgtttaga
     9541 cctatttttg gagaataaag caaaaataat acttgactga aggtgtatga caaactttct
     9601 tcgtgggttc tagttgttgc ggggcgtgaa cctagtacaa gaaagtaaaa aggcaaaaga
     9661 aagaatgctt gttttgtaag ctttatggct attttaaatg agtggcttat ttacggcata
     9721 ctgtactatt ccttcagaaa ttgatagtcg tcaatcagta tatattcatt cagagttctg
     9781 cataatgaga tttcattaaa aagccactta gtttattgaa ttaggcacag caaaaagtgg
     9841 attatcttaa ataatttcac aacattctgg taagagcaat ctgtgaattt ttcgattaaa
     9901 aggagcaact tcacgatatc aaagattaac taaaaatatc aaaaaattaa caagacttaa
     9961 atcaatacaa tgagcttaaa ctgataggtt taaatggaaa atgacttcaa gtaagcaacc
    10021 ttttgagttg ccgagttttt atgtaccttg gccggcacgg ctgaacccaa acctggaagc
    10081 ggcacgggta cattctaaag cttgggctta tgaaatggga attttgggtg gggcagaggg
    10141 atcagaagat tatgggattt gggatgagcg caagtttgat gcccatgact atgcactatt
    10201 gtgttcctat acccatccag atgccgatga acagatgctc aatctggtaa ctgactggta
    10261 tgtttgggta tttttcttcg acgatcactt cctggagctt tacaagcgta cccaagatat
    10321 ggcgggggcc aagaagtacc tcaatggact accagcgttt atgcctgtgc agccccaaga
    10381 aacgccgcca gaacccacca atgccgtgga actgggttta gtagacctct ggaatcgcac
    10441 catccccaat gcctcccaag actgggtaat ccgattttcg gaaagtacca tcaatcttct
    10501 caaagaatct cagtgggaac tcgccaatat cagccagcat cgagttgcta accccattga
    10561 gtacattgag atgcgccgta aggtaggggg agcgccctgg tcagctaacc tagtggaaca
    10621 cgcggttggg tcagaaattc cggcggcgat cgcgccatct cgaccaatgc gtgtcctcaa
    10681 agataccttt tctgatggag tacatctgcg aaatgacatc ttctcctacc aaagagaagt
    10741 agaagaagaa ggagaaaatg caaactgtat tctggtttta gaaaaattcc tggatgtgag
    10801 tacccaagaa gcggccaatc tcactaacga cttactcaca tctagggtgc aacagtttga
    10861 gaacaccttt gttactgaac tgccttcttt gttcgaggaa tatagtttga ctcctgatga
    10921 gcgtctgaaa gtcgtcctat atgccaaagg acttcaggac tggcaatcgg ggggtcatga
    10981 gtggcacatg cgatcgagcc gctacatgaa ccagacatca gacaaatctt cgccagcaag
    11041 ttggttttta ggtggcccca ctggactagg cacatcggcc gcccgtctgg gagccttata
    11101 cgatagtttg ggactaaaac ggtttaaaag cttcacccat gttccctatc agcctgtagg
    11161 gccagtcacc ctgccacagt tttatatgcc cttttccacc agtttgaatc cccatctaga
    11221 cgacgctcgg cggcattcta aggaatgggc acgtcaaatg gggatgctag acagactacc
    11281 agggatgccc agcatttaca tctgggatga ccataaattt gatgtagcag acgtagcctt
    11341 atgcggtgct tatattcatc ccaatgggtc tagtgctgag ttgaatatca cagcctgctg
    11401 gctggtttgg ggaacctatg ctgatgacta cttcccggca ctgtatggct atagccgcaa
    11461 catggctggg gcgaaaatct tcaacgctag gttgtcggcc tttatgcccc ttgatgagag
    11521 tcctgttccc gaagccacta acccagtcga acagggtttg gcggatattt gggcgcggac
    11581 ggctggcccc atgaacccta atgctcgccg tcagtttcgt cgggcgattg aagatatgac
    11641 ggaaagctgg ttatgggaac tagctaacca aatccaaaat cgcattccag acccgataga
    11701 ctatgtggaa atgcgtcgta agacctttgg ttccgatcta accatgagcc tgtctcgact
    11761 ttcccaagga gacgagatcc caccagagat attccgcacc cgaaccatgc agaatatcga
    11821 taattcggct gctgatttcg cctgtctgac aaatgatgtt ttctcttacc agaaagaaat
    11881 cgaatttgag ggcgagatta ataacggtgt gctggcggtt cagaatttcc tgaactgcga
    11941 tatcccccac gctgtggcaa ttgttaacga cctgatgacc tctcgtgccc ttcagtttga
    12001 acatattgtt gctactgaac tccctgcctt gtgtgatgat ttcgggctgg atacaagtac
    12061 ccgtaagaaa ctgtacggat atatcaagaa actagagcag tggatgtgtg gggtactcaa
    12121 atggcataga gcagtagacc gctataagga atttgaattg cggaataact cgacagaaaa
    12181 acgcttactc caaggcccta cagggttagg cactgcggcg atccagatta gaccaagggt
    12241 cggtcaggaa acaactcaaa ccaatgttca gccagtggtg cagaacttac taagtagtcc
    12301 aacagggtta gggacttcag cgaccaaaat cggatcgcta ttaggaaaga aaggttagtt
    12361 caactcaatc tgagtgctga ttccggtcaa tcaaatagtt tgtcaataaa cactatcaac
    12421 ggagatttat catgactaat gcagcaaata cttccctaga aaatcaaatt gagcaacagc
    12481 caataagttt ggggacagaa gcggcgcgta atttggcaac aaccaccaaa acccaacccc
    12541 agatgcaggg cattacctca cggtggctct taaaactgct gccttgggta gaaacagtgg
    12601 gtggcagcta tcgggtcaac cgccgcttaa cctatacagt tggggatgga cgggtcagct
    12661 ttaccaatac aggatctcaa atacaggtca ttcctcaaga actcggtgag ttacctttgt
    12721 ttcggggatt tgaagatgtt ggagtcttaa atgccttagc cagtcaattt gtacaacaag
    12781 aatttgctgc tggagatgtc atcatacagg caggtcaagc ggccgatcaa gtattgttga
    12841 ttgctcatgg taaggtcaat aaaattggcc caggcaagta tgacgatcaa gttgttttag
    12901 ctgtattagc tgatggcgac cattttggtg actacgcttt agtggaatcc caagatatct
    12961 gggatgtcac cctcacagcc attactcgtt gcaccatttt gtctttgcct caagcagcct
    13021 ttcaaaacct agttaaccaa tctgaagctt tacaagcgca agtggatcga ttcagagaaa
    13081 aattgcgcca accccaaaac caatatgggg aagcctcgat tgatattacc tccggccacc
    13141 ttgcagaggc actattacca gggacttttg cagattatga aatcaatcca cgggaatatg
    13201 agttaagcgt tgctcaaacc gttttgcaaa tcaatacgcg ggttgctgat ctctacaacg
    13261 aacccatgaa tcagactgag gaacaattgc gactcaccat cgaagcatta cgggaacgcc
    13321 aagaacacga gatggtgaac aatcgtaact tcggactgtt acacaatgcc gatctcaaac
    13381 aacgcatctt tacccgcagt ggccccccaa ctcctgatga tctcgatgag ttgatctcta
    13441 ttgtttggaa agaaccgagc tttttcttag ctcatccccg cactattgct gcttttggtc
    13501 gggaatgcaa ccgtctagga ctctatcccg atcctatccc cacgggtaac agtgcaattc
    13561 catcttggcg tggtattcct atctatcctt gcaataagat tccagttaca aaagagcgta
    13621 ctagctcgat tatcttaatg cgtgtgggag caaccaacca gggtgtcatt ggtcttcata
    13681 aaactggcat tcctgatgaa tatcagccta gtttatctgt gcgcttcatg ggtattaacg
    13741 aaaaggctgt tatttcctat ctagttagtg cttactactc tacagccatt cttgttcctg
    13801 acgcattagg catccttgaa gatatagaaa ttggtctcta agtagccatc atgaactgct
    13861 tacaccagaa cagatgaaag aggaactggg gactagtatt ttatacttag aactcagcac
    13921 tctcaagtca gtcggacatc ctctttaaag tagaggcaaa cagctgtttg cctctaactc
    13981 ctgatgctct cttttaggaa tgtaaattta gttgcatgaa actttaactt tatgacagat
    14041 gctttgattc ggcctaattt agaccaagaa aataggcaac tccagatgag cttaagcacc
    14101 aaaggggcgc ggaatttagc caaaaccacg aaaactccgc cccaaatgca gggcattacc
    14161 cccaggtggt tgttacagat gttgccttgg gtgcaagtca cgggtggagc ctatcgagtt
    14221 aaccgtcgct taacctatga tgttggtaat ggacgagtta gctttacaaa tacaggaacc
    14281 caggtgcggg ttattccgca agccctttgt gaactatctt tactgcgtgg atttgaggat
    14341 attgaggtac tcaatgcctt ggcagaccgc tttgtgcaac aagaatttgc ctctggtgag
    14401 gtaattgtac aggaaggtca accagccgac caggtgttat taattgctca tggtaaagtt
    14461 aataagctga aggcaggaaa gtatgagaca gaagctttac gggatattct agctgagggc
    14521 gattgttttg gtggcgaagc tatagttctg tctcaggaaa cttgggaggt tagtctcaga
    14581 gctattacac gctgcatagt tttgtctttg ccaatacagg cgtttcggga gttgctaaac
    14641 cagtctgaag cgttgcagac ccaggtcgat cgcttgagag ctatattgag caaacctcag
    14701 gataggcaca atcaagccga gatcgccgtg tctgctggtc atagtcaaga aactgagtta
    14761 cccaggacat ttgttgatta cgacttgagt ccacgggagt atgagttaag cgtcgctcaa
    14821 accattttac aggtgaatac gcgagttgct gacctctaca atgaaccgat gaaccagaca
    14881 gagcagcaat tacggctgac tattgaagcg ttgcgggaac ggcaagaata cgaaatgctg
    14941 aataaccctg gtttcgggtt gttgcacaat gctgatctta agcaacgcat ctttactcgc
    15001 accggcccac cgactccaga tgattttgat gaattgctgt ctcggcggcg caaatcccat
    15061 tttttcctag ctcaccctcg tgcgatcgct gcttttaacc gggaatgtaa ccgtcgtgga
    15121 atctattccc caagcaaaga agtcaacggc aagattgtac ctgcgtggcg caattatcca
    15181 atttttcctt gtaacaaaat tccgatcact aaagagggta ctacctctat tttgatattc
    15241 cgtgtcggtg aagaaaacca aggggtgata ggtctacaca aaacgggtat ccctgatgaa
    15301 taccaaccta gtctgtctgt gcggtttttg ggcatcaacg aaaaagcgat catttcttac
    15361 cttgtcagcg cctactactc cgcagccatt ctcatccccg atgcacttgg catcctagaa
    15421 gatgtggaaa ttggacactg agggaagggt aaacctcact ttttgtacag tgactaaatt
    15481 aaatattgtc gcgacaaatt gctgtttttg tgaataatca ctgtatcacc gaacaaggca
    15541 aaagaaactg ccaaaaaagc aaaagttaaa aaacaataca gttcagaatg agcaacaaaa
    15601 cacttgtaga gacggcgatt tatcgcgtct cgaaaactgg ttaatgaaca cctaatttaa
    15661 ttcattgtta ttggctacaa caatcagatt gtcagggcaa taaattgtga agtatgactg
    15721 aaaattttca tcaatagtta gagttgattg tatttaatgc ttaaccttta tttcttgctc
    15781 taaaaacaga ttgccaatat caaataaaag ttgtatggta cctcgatagc caaccttggt
    15841 aaactgacca tgatctaagc ggtcaaaaat gggaattcct tgacgataga gaggaatttt
    15901 taagcgttga gcgatcgcta ctccatgaga gttggtaatg agtaaatcag acccaatcgc
    15961 cagttgctca aagtcttcca aatcgccgat agtgacgctc ttgatcggca gtttttctaa
    16021 cagaggaaag cgtgttgttg tcactgctga gtgaatctca actcctagcg atcgcaaaaa
    16081 agcaactgtt gaccaaagta aatctggttc cagcgccaaa gaaactcgct tgcaaccaaa
    16141 gtaaaagtga ttttccaaca tcatatattg caactgcctg cgttgacggc ggtatttctg
    16201 tggtacgctg acgccactga tatccgccaa tgcttttagg aatttatcta ctgctactag
    16261 tcccgtcagt tcactaaata cctcataagg tatattgaat ctctgctcca aaatttgcgc
    16321 tgcaccccgc atactatcac ccagcgccaa agtgaataca gaactaccaa ttgagcgcaa
    16381 ctgtgctgta tttgtgccat tagctgtaat ggcactagaa gaatcttcta tatgaccatc
    16441 taatgagcta gaaaggtcag gtacaacaat aggtataagt ccaaaagagg taacaatctc
    16501 tttgatttcc tgtacatccc ctggtgtgaa ggcagaactc gccaaaatag tgatttgtgt
    16561 aggagaagcg tcttgcttgg agcttttttg gggaatttcc ctgactatac tctcaactgc
    16621 accagcaaag ccatcctgta atgtaccttt gaaatctggt gtagagacaa gcacaattgg
    16681 taaataatcc agttctgggt gacggtggcg aatctccttg acaaagcgtc ccatatcatc
    16741 gtcgcccaat acgtcgtagg atacgaaatc tacgtctgag taagcgccat tttcttcaag
    16801 gaagttaatg gcagtgatga taccccggcc agcgcaaccc acacccggtt ctggcccacc
    16861 agattctacg catctgatat cgcggaaacc agtgatcaca acttcttcta gttcaatatc
    16921 ttccacagcg ccccgttcag cagctaaatg cagcacggta gtttgagctt tacagtgcaa
    16981 aatcaaacgg gtagagtcag ctttcgggtc acacccgaca atcaagatgc gtttacccac
    17041 ttctgccatc gcagcaaggg tgttttggga agtagtagat ttaccaatac cacctttacc
    17101 gtagaaagca atctgtctaa ttctttcatc ggacatgata atttatcctg caattgtttg
    17161 tttggtgagt ctgtaggtta atgaggcgat cgcacaaact agtgcctacc agaggtactt
    17221 gcttgctgta acttgatagc agtaacttga tgtagaacgt tgttggaggc gctcgttcta
    17281 cagcaaaaag agtctgtatc cagaacatat ttaacttgtg gtcagttttt gttggccatt
    17341 agtcattgtt ttttctgact aatagctaga gcgataagac atcactcaag gaatattgca
    17401 agtattacca gaccctcgct gaaattattt ctctggcagt agtaatacca actagacaaa
    17461 agaaagctac agattccaag ccggaaactc aaattcaatc cgaattacga attcagcatt
    17521 atcagttgtt gtcatctcct gaaggttgct catacctaaa gagttgttgc agcaggattt
    17581 aaatttacgc caagtttccc caaacaacac aaccaaccat tgcaattcac tctaaacagt
    17641 cgctacaact tccccgattt tgctgatatc gtaaccaccg agaatttcaa attgggagtg
    17701 aaccatccga tgtcccaaag tactgagcaa ctgctgtact ggtgcttctt ccagatattc
    17761 cttgagaatc accaaatcat atcgtgactg atgtaaaggg ataaatccca gcccaaaggc
    17821 ggtagctaca gatgccgtac tcataccagc atcggcagat ccttggacta cagcttgggc
    17881 aacatcttgg tgacttttga gtacattatc aaagccctga acggtatcga acggtatctg
    17941 ctccttttgg agtgtttgtt ccaaaagcat ccgactacca gaacctattt cgcggttaac
    18001 aatagtcgct cccccagcaa ctaagtcagt aactgttcta attcccattg gattgccaga
    18061 ctttaacaaa agtccctcct cccagacacc aagggtaatt aaaactgctt ccctcccagc
    18121 cagaacatct cgaacaaagg gagtattata ctcaccagtc tcaggatcgt acagatgcat
    18181 cccagcgatg tgcgcctcac ctgtgcatag actgtgcaat gcagccatgc tattggcgaa
    18241 gttatattgg actcgcagtt gaggatgcca gcgttcggtg gctcttgccc atagtgaaat
    18301 cacaggggca caaccagcaa tcacaacggt gttgtgaagt gtttcgagat tatcgtctag
    18361 taacctgact cgaactttat ttgtacctgc aacacttgtg ctttcaccat cagccggaat
    18421 catatcttgg cgaaaagcat ccttgccaat caaggggtaa gctatccatt gtcctcccac
    18481 acgagccatg ctaactcgta gctgctgacc attaggaaca ggtttggcaa gaacggcttc
    18541 aatttcaggt aaatcccgct ctaaccagaa tagatcctca acttgacagc caagcgcttt
    18601 ggccaagcga agtgttatgg ctactgaggg agcatatagt cccgactcta caccactaat
    18661 agtctgacga gtcacactag cgatgttagc caaatcttgt tggctcatgc ctaagcgagt
    18721 tctaatggac ttcaagttat tacggaggtc actatcctgc ttcattggct ttgtctctta
    18781 gtttcaaaaa gccgtagcgg atttaaacat tgcatctgcc aaggcgaaag tattgtcttt
    18841 gagtttatat catttctctt tgaagacttt ttgtactttc gctgtcttga ttccccatac
    18901 aaaaagacta tcacagaaat tgcaaatttg cttgcgaagc gcaaattatt tttgcggatg
    18961 gttacttttt agccgctttt ttggctcaaa agccccaaat tccgataaac agagcattca
    19021 tctagcagaa ttttttacca actaaattgg taaaaagtag tgtttaatac agttttagag
    19081 attagtttca gctttgatgc ttgataggcg agtaacacaa acagtagaaa acataccaac
    19141 caatttcgtg ttttggggta aattttgccc tgatgaaaaa ttacctattt gactaaagtg
    19201 aatatgcaga tagcatcagc aaagaattgc tgttttaagt ttttgcacaa tcaattaggt
    19261 attgatcaaa gtatccaaca gatggcaaac aaaggaatgg agaaagtaat gattactgaa
    19321 gaagacttag cacagcaatt taacctaatt attgaacaca ctcacccaca agtatggaaa
    19381 ctgttaagcc aatgttatgt aaaggtgata gttcctcatc ctcacttaac aagagtgaat
    19441 ataaaaacat gcatccgcca tgcaaaatac attggtattt attgccctga cagactaatt
    19501 agtggtgtat tagaacaaaa aaaactactt aaagaagtag cagaatactt gggtttagta
    19561 gaagttgtgt gcttgaatgc caatcactta atgcgcgatc cactttcaaa tctaaagcaa
    19621 acttatcctc agttgtggtt agatttgttg tggattgtca cccaagaaaa ataatctagt
    19681 caacctgatt tttctgcaat attcaatctg caaaaaatca aaattaccaa tcttcatcgc
    19741 agcttcatta tttttgaagc ttgccaaaac attatgaatc aaccatgcct gcatccagat
    19801 gatttgcctt cacctcaaac aatcaagctg agtggaatac tatttagaca gcttgaagaa
    19861 gcaactaaaa aaaacttttt cttagcgtgc gatcgcatga cacggatttt gttatcgagt
    19921 tgtcattggt atttccaaat tatttttgaa gcttgccaaa acattatgaa tcaaccatgc
    19981 ctgcatccag atgatttgcc ttcacctcaa acaatcaagc tgagtggaat actatttaga
    20041 cagcttgaag aagcaactaa aaaaaacttt ttcttagcgg gcgatcgcat gacacggatt
    20101 ttgttatcga gttgtcattg gtatttccaa atcaatagtg gtgttttgac gttgatcgtg
    20161 atttgtaata atatgaaaag ctatcgtcag atcatgaaaa ctgttcccca atttgccggt
    20221 cacttaaaac agtttgccaa tagagctaaa atcactgtta gttctccagt tgacaaaggt
    20281 ataccttggg tactcaatat agataattcc ttacctgaag gagatttgcc taatacctga
    20341 tagagcaacc agaatttgtt ctaggaaaat catcacttca tctgcattaa tcattgaata
    20401 gacttgttgt tcttcactgt atataagttt tctgctaaat ctttcggtat gatggaagta
    20461 atgcctactc ctagaaaaat ttccaagatt acatcaggct tctctacatt tttgtgaatg
    20521 gttttttgag gagattgcag acactatcct aatcctatat atacttttct gtgtctgact
    20581 aaatagtagg gaaccctgat gttatattag ggaaatttgc actaagtaag cttttaattc
    20641 accgctcttg ttaactaact aattgtaatt aattatacta tttactcgct ggacacttaa
    20701 gttagctgtc caggcaataa aaagcaatat atgctaagat tgtatcaaaa tatagcaatt
    20761 attcaagagc aatttagaat aattttgcgc tttgttgagt aaaaaagcta aaatctacga
    20821 tttttggaga tttttaggtt atgacaacct cacaggagag gattatcccg acggacttgc
    20881 gaaacgaaat gtcgcagtct tatctggaat acgccatgag cgtgatagtg ggtcgggcgc
    20941 tgccagatgc cagggatggt ctaaaacctg tgcatcgtcg cattctctac gcaatgcacg
    21001 agctaggtct gctccacgat cgccccttta agaaatgcgc ccgtgtggta ggggaagtat
    21061 taggtaaata tcatccccac ggcgacacgg cagtatatga tgccttggtg cggatggcac
    21121 aggatttttc tatgcgatcg cccctagtta acgggcatgg taactttggt tctgtagata
    21181 acgatccgcc agccgccatg cggtacacag aatgccgctt gcaagcttta actagtgctg
    21241 gtctactcca cgacatcgaa ttagaaactg tagactttgc cgataacttc gacggttccc
    21301 aacaagaacc gacagtttta ccagcacgga ttccccagtt attgctcaac ggttcctctg
    21361 ggattgccgt gggtatggcc accaacattc ccccccacaa cttgggcgaa ttgattgatg
    21421 ccttggtagc tgtaatccac aatccagaaa tcaccgatct cgaattaatg cagtatgtcc
    21481 acggcccaga ttttccaact ggggcgcaga ttttggggac atctgccatt cgtgaagctt
    21541 acaccactgg gcgtggttct attaccatgc gtggtgtcgc taacattgaa accgttgaac
    21601 aacggggacg cccagataga gaagcaatta tcattaccga attgccctat caaaccaata
    21661 aagcggcgct gattgaaaaa atcgccgaaa tggtgaacga aaagcggcta gagggcatcg
    21721 cagatataag ggatgaaagc gatcgcgatg ggatgcgaat tgtcatcgaa ctcaagcgtg
    21781 atgcttatcc ccgcgtcgtt ctgaacaacc tctacaagca aacgccactg caagccaact
    21841 tcggcgcaaa tatgctggcg ttggtgaata gcgaacctca agtacttacc cttaagcagt
    21901 ttttaaccgt ctttttggat ttccgcatcg aatccattgc tagacgcacc cgttacgaac
    21961 tgcgaaaagc cgaggaacgc gaccatctcc tgcaagggtt attaattgcc ctggctcagt
    22021 tagatccaat tattgtcttg attcgtcatg cgcccgatgc gcccacagct aaaggtgaat
    22081 taatcacaaa ttacggactt tcagaagtgc aagcagatgc gattttgcaa atgcaattgc
    22141 ggcgcttgac tgccttagaa gcagacaaaa tccgtctgga acacgatgaa ttgcaagcga
    22201 agattaccga cttgcaggat attttggccc ggcgcgagag agtgctagaa atcattgaaa
    22261 ctgaagttgg gcaactcaaa actagctttg ccacaccccg gcgcacggtg attttaccag
    22321 gggaaggcga attagacgat cgcgacctca ttgccaat
//
