LOCUS       NZ_CP040272            23309 bp    DNA     circular CON 31-AUG-2024
DEFINITION  Nostoc sp. C052 chromosome, complete genome.
ACCESSION   NZ_CP040272
VERSION     NZ_CP040272.1
KEYWORDS    RefSeq.
SOURCE      Nostoc sp. C052
  ORGANISM  Nostoc sp. C052
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
            Nostoc.
REFERENCE   1  (bases 1 to 7828336)
  AUTHORS   Li,F.-W.
  TITLE     Complete genomes of symbiotic cyanobacteria from bryophytes provide
            new insights into the evolution of Vanadium-type nitrogenase
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7828336)
  AUTHORS   Li,F.-W.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2019) Boyce Thompson Institute, Boyce Thompson
            Institute, 533 Tower Rd, Ithaca, NY 14853, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.4.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 84.0x
            Sequencing Technology             :: Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013393905.1-RS_2024_08_31
            Annotation Date                   :: 08/31/2024 08:18:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,527
            CDSs (total)                      :: 8,409
            Genes (coding)                    :: 8,174
            CDSs (with protein)               :: 8,174
            Genes (RNA)                       :: 118
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 104
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 235
            CDSs (without protein)            :: 235
            Pseudo Genes (ambiguous residues) :: 0 of 235
            Pseudo Genes (frameshifted)       :: 84 of 235
            Pseudo Genes (incomplete)         :: 168 of 235
            Pseudo Genes (internal stop)      :: 38 of 235
            Pseudo Genes (multiple problems)  :: 50 of 235
            CRISPR Arrays                     :: 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:15:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6502742
            Orig. end                         :: 6526051
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040272.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Fay-Wei Li, Boyce Thompson
            Institute, 533 Tower Rd., Ithaca, NY 14853, USA.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23309
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="21"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23309
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23309
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13309](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13309
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    274..287
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.84"
                     /tool="antismash"
     gene            complement(342..797)
                     /locus_tag="FD723_RS26860"
                     /old_locus_tag="FD723_26785"
     CDS             complement(342..797)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012410979.1"
                     /locus_tag="FD723_RS26860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_26785"
                     /product="DUF2141 domain-containing protein"
                     /protein_id="WP_179068092.1"
                     /transl_table=11
                     /translation="MVKGLRVSLLLLAVLGNLAWSLSAKANFNGKLTVEIDGLKNKEGQ
                     VCASIFASSEGFPSDRDRVLQKQCTKITDNPLPITFDNLKAGSYAVAVFHDQNNDRILN
                     RNILGIPSEGFGFSSNPEIRTRAPKFSEAAFLVAGPDTNIKIQLKYF"
     gene            complement(1180..2640)
                     /locus_tag="FD723_RS26865"
                     /old_locus_tag="FD723_26790"
     CDS             complement(1180..2640)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008519 - ammonium channel activity
                     [Evidence IEA]"
                     /GO_process="GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012410978.1"
                     /locus_tag="FD723_RS26865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_26790"
                     /product="ammonium transporter"
                     /protein_id="WP_179068093.1"
                     /transl_table=11
                     /translation="MNKRIRPWHRLLALAIASMIFAVFAPTIVQAADPPTIQSLSETTT
                     KLQISIDTTWVLITGFLVFFMQTGFAMLEAGLIRQRGVVNALLENFIDAAVTILVWWGI
                     GFGIAFGTSAGGLIGIDNFFLSQLPGVDGSYPLGAPGSTAAINTYSLFFFQFAFAATAS
                     TITTGSMAGRTDFVGDLIYSAIMGAISYPLIVHWAWNSGGWLAKLSYHDFAGSSVVHSV
                     GGWTALVGAYLLGPRPGRPAWGTLPPAHNLGLATLGTMILWFGWYGFNPGSTLSTGNTG
                     LIGLVTVNTTLAAGAGALSAIIFQYTRTGKWDLVYSLNGSLAGLVAITAPCAYVAPWAS
                     VLIGLTGGILVTLGVDLIESLHIDDPVGAFAVHGINGMMGTLSVGFLGQAELTLNKKAG
                     LFLGGGFDLLAIQLLGVVAIAVFTVAFTFLMFGGLKALGRLRVNPEADRIGIDVYEHGA
                     SVWPDVYAIEEKETNRAKTPELGAFDSE"
     misc_feature    3309..3322
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.52"
                     /tool="antismash"
     misc_feature    3321..3338
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 18.9"
                     /tool="antismash"
     misc_feature    3574..3589
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: medium, score: 25.6"
                     /tool="antismash"
     gene            complement(3873..5828)
                     /gene="dnaG"
                     /locus_tag="FD723_RS26870"
                     /old_locus_tag="FD723_26795"
     CDS             complement(3873..5828)
                     /GO_function="GO:0003896 - DNA primase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /gene="dnaG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011320488.1"
                     /locus_tag="FD723_RS26870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_26795"
                     /product="DNA primase"
                     /protein_id="WP_179068094.1"
                     /transl_table=11
                     /translation="MQIPRLHPDTIEEVKLRADIVDVVSEYVVLRKRGKDFVGLCPFHD
                     EKSPSFTVSQTKQMYYCFGCQAGGNAIKFVMELGKRSFADVVLDLARRYQVPVQTLEPE
                     QRQELQRQLSLREQLYEVLASSAQFYQHALRQSQGQKALQYLQSNRKFKEETIQQFGLG
                     FAPAGWETLYRYLVEDKHYPVQILEKAGLIKPRKEGGGYYDVFRDRLMIPIRDVQGRVI
                     AFGGRTLTDEQPKYLNSPETELFSKGKTLFALDQAKGGISQLDQAVVVEGYFDAIALHA
                     AGINNAVASLGTALSLEQVRLILRYTESKQLVLNFDADKAGTNATERAIGEIAELAYKG
                     EVQLKILNLPDGKDADEYLHSHTQEDYGELLKNAPLWLDWQIQQIIQDRDLKQATDFQQ
                     VTQQLVKLLKNIANSDTRNYYVSYCAEILSLGDTRLIPLRVENLLTQIAPAAAIYSKPV
                     SAKKAWGGSQSPLSISNSPLPTERSLLEHAEALLLRIYLHCPEQRQAIIDELEERDLQF
                     SLSHHRFLWQQILEISSGDGETKNLVSLPNLISRLQDQFLEFDSEIGLISHLFHVDEKN
                     QKEILRTPQVVQAAIACMDLVMLEKRYRHFLELWQQTDPEAEPERYQSYYQAFYAEKIK
                     LQKIDRQRLFSITELI"
     misc_feature    5870..5890
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.5"
                     /tool="antismash"
     gene            5987..7339
                     /locus_tag="FD723_RS26875"
                     /old_locus_tag="FD723_26800"
     CDS             5987..7339
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016872313.1"
                     /locus_tag="FD723_RS26875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_26800"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_179068095.1"
                     /transl_table=11
                     /translation="MGRIFISAAHGGKEAGGIDQGAIAGGTTEAKEMILLRDLIVTELR
                     ARSLEILAVPDDLSAAQTITWINSRGRRGDVALEIAANAASSPSVRGASVFYIANNSDR
                     KSNAEQLLVGLLRRVPQLPNRGVKPDTDSGLGSLAFCRQTTLPALVMQVGFLSNPEDRA
                     LLQTRRRDFALGIVDGLVTWSRVIDPTPGTPAEANYPPINININGQSYTEQGVLVNGNA
                     YIPIDLVDLLRIDLSKAANVNKITYHKIVYVKAIELRDFNVAVTWDAATRTVSLRSNLV
                     VCPGQFSRVMSNGTTSEIQLQLFLKNNNQNALAKFPDIPKLYREEAGIEGVNYDIAFCQ
                     MCVETGFLQFGGDIKPEQNNFAGLGAIGGGAEAASFPSARIGVRAHIQHLKAYASLEPL
                     VQEVVDPRFRFVTRGIAPLIDQLAGRWSADLDYGTKISAMLKRLYESAGLL"
     gene            complement(7454..9301)
                     /locus_tag="FD723_RS26880"
                     /old_locus_tag="FD723_26805"
     CDS             complement(7454..9301)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010997161.1"
                     /locus_tag="FD723_RS26880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_26805"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_179068096.1"
                     /transl_table=11
                     /translation="MPDSLPLSDRYLALIDEIVETTLKGKISSVEQVYQMLLKGITSGT
                     GEVFELALSDRLNAFQSQVDSEKDELKKAKATRSLRAIKTIQSQWQRWQEQNKATEAIA
                     SAVTEITTATANERLATFIRVTDPNQKYPLNLQQLQQLSKALQQFAQADSDLQQFSEGI
                     TRGLASWQRLQDNLLSWMYEQKESLGFGGVPGERGPWASWAKQLSSELPQTLLRTLARE
                     ESAIEFAQRQRGITLRDWVEMALILQFLQRGLINWFDQQAYDVKAGPKLSISTFLTFAV
                     IWSQLASGFSSIGTVYSDACSQIMLQILRTFAQRPYFPFYGGIFASFTGTYLRDALDYL
                     DEPLRRGEGTQEKARILTLLGYSQRALGQYQRSIDFHQQALEIARNAGDRACEIANLNH
                     LSRTYVQQQNYAEAINYSQRALILSRQAGDRTGEANALVNLGYSEVMQAQELENLEPET
                     YEAAINYLEQGLKLSEKLGDIQSKALCVSSLGIAYLVIGEHQTAIKYLEDGFKTAQVSG
                     DLYLQGRNLAYLAEAYYHLQNSEKTVYTGCLGMYLLQQIASREWRQPAGLLTILQGQIG
                     VEAFQKLLQQHRPKMIAVIGVDGYDHIPQLLEEYKGDIS"
     gene            9524..9814
                     /locus_tag="FD723_RS26885"
                     /old_locus_tag="FD723_26810"
     CDS             9524..9814
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03798"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012411338.1"
                     /locus_tag="FD723_RS26885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_26810"
                     /product="Nif11-like leader peptide family RiPP precursor"
                     /protein_id="WP_179068097.1"
                     /sec_met_domain="TIGR03798 (E-value: 1.2e-08, bitscore:
                     33.6, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLHQIKELLQNAQLQQQVKAAANQAEAVKVLAIASAEKGYNFTVE
                     AISQMLSELTFVDSNELSEEELLSVSGGMMSESAAKLCHTDSCGGGHGGCC"
     gene            10001..13309
                     /locus_tag="FD723_RS26890"
                     /old_locus_tag="FD723_26815"
     CDS             10001..13309
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012411340.1"
                     /locus_tag="FD723_RS26890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_26815"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_179068098.1"
                     /sec_met_domain="DUF4135 (E-value: 7.2e-118, bitscore:
                     392.5, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 7.8e-60, bitscore:
                     201.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVQQVVRLSQQKTSDDLRAIAANASFLWERLDESRFAIDVDRVNE
                     QEINHRRHRWCEVAAEGKWNTLHKRLQWEELDLDTVSSRLGTIELLADQPLPEWAETLQ
                     QIIQTATGFNSATEVFLPIDSQNPIAFEDILLPAILVARQQLLIRCNSQFTQDCLPLSI
                     LSYDAYSSLERSLLQRLAGICTKTLDFEFSQVRPFGQSLLGLLGLETENNNIHYTKFVN
                     QLLEDGMLTFFQKYPVLGRLMATAVNFWVEFTAEFLERLVADRTDIQRTFDQTIVPFSQ
                     NKVTEIQTSLSDPHKRGRTVILLTFESGLKLVYKPKDLGLEVVFNQFLGWCNQHSNLLD
                     FKIIQVLKRKGYGWVEYVEQLPCVDEAAARRFYQRSGMLLCVLYALRATDCHYENLIAN
                     GEHLVLIDMETLLHHEPNLIEDSPLTQDLEATATRQFWDSVLRTGLLPRWDFSGDRSVA
                     YDISGLGSTDPRLSPRKVPRWQNINTDNMQLLSESVTLPIAKNVPCLGEVPLSPNDYQL
                     QITTGFEQMYRFLMAHKDFLLSPQSLLSAMQNQQVRFIFRNTRIYGIILQKTLSPDYLK
                     HGVDYSIQLDVLSRAFLVAQEKPNAFPVLSAELRAMEQLDVPFFTASAVVDELSLNGSS
                     AIPNYFKQPSYQDLLNQLQSLDETDLARQVAIIQGSFDAKIATTHSRKGGQWKSESLPF
                     LSSEQLIAEAKEIANELETRAISDPDGSVNWIGLDFVPRAERYQLQVLNNCLSDGRSGV
                     ALFLAALSQVTGDSRYRDLAFRTLQSLRRQIHTVDPETWQRMASFMGVGGATGLGSMIY
                     SLVKISQFFNDITLLQDAQVLADLMTPELIAADEHLDIMSGAAGAILGLLSLHQATGEA
                     TVLEKAIACGQHLINRQVSHNGAPKAWHTFWDKPLTGFSHGAAGISYALLRLYAVTLES
                     KYLEAGLAGIEYERSVFCESTANWPDFRRMGQPGQPDFANKWCHGAAGIALGRLGSLRI
                     VETPEIQQEIEIALQTTQNFGLQAIDHLCCGNLGRAEVLLVGAKICSRPDWHHIAHQNV
                     TNVVARAKRTGAYQLFPNLPNSVFNPGFLPGISGIGYQLLRLANNNLPSILLWD"
     CDS             complement(13441..13617)
                     /gene="allorf_6516183_6516359"
                     /locus_tag="allorf_6516183_6516359"
                     /protein_id="allorf_6516183_6516359"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MEEAIILPLDLTDTLYQRRSSRAAIALNPQRHQIVLFRWVSPISY
                     KRPSLAGLYISRC"
     CDS_motif       complement(13546..13617)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MEEAIILPLDLTDTLYQRRSSRAA"
                     /locus_tag="allorf_6516183_6516359_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13441..13545)
                     /prepeptide="core"
                     /locus_tag="allorf_6516183_6516359_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.30"
                     /molecular_weight="3911.6"
                     /monoisotopic_mass="3909.2"
                     /core_sequence="IALNPQRHQIVLFRWVSPISYKRPSLAGLYISRC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEEAIILPLDLTDTLYQRRSSRAA"
                     /leader_location="[13545:13617](-)"
                     /alternative_weights="3929.6"
                     /alternative_weights="3947.6"
                     /alternative_weights="3965.7"
     gene            13758..14405
                     /locus_tag="FD723_RS26895"
                     /old_locus_tag="FD723_26820"
     CDS             13758..14405
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FD723_RS26895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FD723_26820"
                     /product="hypothetical protein"
                     /protein_id="WP_179068099.1"
                     /transl_table=11
                     /translation="MFRKFPSLIASRVFAVGLLLVFGFSQVATAQRSSSSDETSFELFP
                     NTQFINCMAATPGVTPRVQAIVKRGNLNDNLTLRLTNFKPGLKFDLFTVENSPQQAFGT
                     PNPKFKNFGLAWYQSDVEPGLVTIKTILLDQIFGFDPQVNLPPTNTFHIGFWFNNPQDA
                     AACGFDVRKPTPFNGEHKAGPLAFISRPNSLTNLGPLCIKPNTSKNPPTCNP"
     misc_feature    14734..14749
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.56"
                     /tool="antismash"
     misc_feature    14765..14783
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.76"
                     /tool="antismash"
     gene            15040..15249
                     /locus_tag="FD723_RS26900"
                     /old_locus_tag="FD723_26830"
     CDS             15040..15249
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017314635.1"
                     /locus_tag="FD723_RS26900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_26830"
                     /product="hypothetical protein"
                     /protein_id="WP_179068100.1"
                     /transl_table=11
                     /translation="MAEHVFHNQLGLEEQTEKLGKQALSLGLIPSFVVHYFPDTWVFYI
                     PNESQSEPLTPEEAYFRLKQLVKQ"
     misc_feature    complement(15045..15059)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.3"
                     /tool="antismash"
     gene            15314..16978
                     /locus_tag="FD723_RS26905"
                     /old_locus_tag="FD723_26835"
     CDS             15314..16978
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012407375.1"
                     /locus_tag="FD723_RS26905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_26835"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_179068101.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.1e-28, bitscore:
                     98.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKPAILTVDDDPEVLQAVSRDLRHQYGDRFRIVRADSGITALDV
                     VQQLKLRNEAVALFLVDQRMPQMGGVEFLEQAKDIFPNAKRALLTAYADTDAAIKSINS
                     ARLDYYLLKPWNPPEEKLYPVLDDLLDDWLAGFRPPFEGIRVIGNRWSPFSHQVKDFLA
                     RNQIPFKWLDIELEPEAAKLVEYAQADCRQQLPLVLFPDGSRLIQPSNLEIAAKIGLQT
                     QAERPFYDLAIVGAGPAGLAAAVYGASEGLSTVLIEREAPGGQAGTSSRIENYLGFPIG
                     LSGNDLARRGVTQARRFGVEILTPQVVTGVRLEDPYRILQLADGSEISCHALLVATGVS
                     YRWLNVPGAEKLTGAGIYYGAAMTEAIACTNEEVYLVGGANSAGQAAMHFCKYARKVIM
                     LVRGESLASSMSQYLIDQIAATENIQVCTSCSVLEVKGEEHLEAIVIAHAKTGQTETVS
                     ARSLFIFIGASPKTDWLDGVIQRDAQGFVITGPDLIHNGKSAPGWNLERSPFLLETNIP
                     GIFAAGDVRYGSIKRVASGVGEGSIAIQFVHRYLSNV"
     gene            17065..18459
                     /locus_tag="FD723_RS26910"
                     /old_locus_tag="FD723_26840"
     CDS             17065..18459
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019489503.1"
                     /locus_tag="FD723_RS26910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_26840"
                     /product="ATP-binding protein"
                     /protein_id="WP_179068102.1"
                     /transl_table=11
                     /translation="MLCVEELINLDPFQQLPKERLQWVCDRAQTVELSAGAVLSYEGDP
                     VCRLFILVKGKINITRRSEGVEIPIGQHEAPSFFGEIPVLTDEPAPVTMRALTNCHIYE
                     MKGDDFRKLLHECRDFERMVFRIMQRRVRGLESFIRGREKMAALGTLAAGLAHELNNPA
                     AALVRTLGEMPAAILELQRMNLVYGQRNVDEAHTQHWLRVRDQGYDAILNNRVDPVTLS
                     DREDILLEWLEDYGVKQAWKLAEPLAEGGVEVETLEQLMERWRNDDTELREMGLHWLAL
                     SFEVMSMIKHGLRGSERISELVQAMKSYSYLDQGIQQEVDIHQGLEDTLRLFAHKLKSG
                     VQVQRNYDRGLPKILAYGSELNQVWTNLIDNAIDAMDGKGLLEIKTWYCDRYAHIDIID
                     SGCGIPLEIKTRIFEPFFTTKSVGHGSGLGLETTRRIVENRHHGTLSFESQPGRTCFTI
                     CLPLTS"
     gene            18814..20253
                     /locus_tag="FD723_RS26915"
                     /old_locus_tag="FD723_26845"
     CDS             18814..20253
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016874025.1"
                     /locus_tag="FD723_RS26915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_26845"
                     /product="NHLP bacteriocin system secretion protein"
                     /protein_id="WP_179068103.1"
                     /transl_table=11
                     /translation="MQLKHSHIFRQEALERLSSPEQLDQAINVVKPQAWLTLSAMSFVV
                     AVAGVWSVFGRIPLTVTGQGILIKPHHVVEFQAPSSGPLLTLKVKAGDIIKQGDVLGII
                     DQSALKQQLQQEQTKLQQLQTQNQETDRLQKLLIDQQIITLGQQRMDLENNLRREEVAP
                     KLRDQTQRAIAQKRQSINSRKQQINYLLKTLKGRVDNRRHLFEQHVISQDMLVQAEQEY
                     FNTQSELSDIDVQLKDLEIQETTTQREYLENLNKIDEIKTKIKDLNTQNTKLREQDLKQ
                     SIDKTNQIREVKRRIAQLELQLSQESRIISKYNGHILEVSVVPGQMMNPGTRLGSIEAE
                     EANSKLVSLVYFANKDGKQIKPGMAVQVTPSFAKREREGGIIGAIADISAFPVTTQDIT
                     AIVGNKEIAASLAGRGEGQVQAFVQLQENPTSVSGYKWSSSDGPALKISSGTITSVQVK
                     VGEKAPISYIIPMLRSWTGIY"
     gene            20313..20689
                     /locus_tag="FD723_RS43095"
                     /old_locus_tag="FD723_26850"
                     /pseudo=""
     CDS             20313..20689
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017451.5"
                     /locus_tag="FD723_RS43095"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_26850"
                     /product="four helix bundle protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MERKKIETFEDLRVWQKGIDLVKEIYLITKYGELNRDFGLRIN"
     gene            20738..22969
                     /locus_tag="FD723_RS26925"
                     /old_locus_tag="FD723_26855"
     CDS             20738..22969
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012412983.1"
                     /locus_tag="FD723_RS26925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_26855"
                     /product="NHLP family bacteriocin export ABC transporter
                     peptidase/permease/ATPase subunit"
                     /protein_id="WP_179068104.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 5.4e-38, bitscore:
                     128.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNSQFPSPKFKPNRVRTSTLLQMEAVECGAAALGIILSYYGRIV
                     PLAKLREECGVSRDGSKAFNILKAAKNYGLNAKGLKLSLEQVTTTRLPYIVFWNFNHFL
                     VVEGYSKKRVYLNDPANGRRTVSWEEFDRAYTGVVLVMEPGADFKKGGKKNHIVSALSS
                     RLQNSRVTILFCLLAGLLLTLPRLAVPAFSQVFIDEILVQDRQDWLRPLLLGMLLTTLL
                     RAFLARLRLTCLRRLMVKLSVSTSGLFLWHILRLPIGFYDQRFAGEISSRMKLNDRVAE
                     VLSGSLATTIIDAVMMVFYLLIMIQYDQLLSAIAVSFAVINILALFFLSQTRVDANMRL
                     AQEYGKVGGVTVSGIQTIETIKASGLESDLFARFAGYYAKALNAQQELGLQTQILTTLP
                     TILTALTTASILLVGGLQVMKGNLSIGMLVAYQSLTLSFLEPVNSLVNFGSTLQTLEAD
                     LNRLDDVLQNPVDLEVEGRGSRGVGEVGEVGDAGGEITFSSLWQLQGNVELRNVTFGYS
                     RVESPLIENLSLTVKPGQRIALVGGSGSGKSTVAKLICGLYQPWQGEICFDGVERSQIK
                     RSVLANSLAMVEQDIFLFAGTVRENITLWDATVLEADLVQACQDAAIHDAIGYLPGKYD
                     FDLIEGGMNISGGQRQRLEIARALVRNPTVLVLDEATSALDAETELIINRNLQQRGCSC
                     IVVAHRLSTIRDCHEIIVLEQGKIVQRGTHEELWQQGGTYLHLLHAAEA"
ORIGIN
        1 tcaatccaag atgaaagccc acaggtgcgg caaaatgcga tccgtgacct gacacgcgtt
       61 tatgacatga tgggtcaaat gactcagatg ttgcgccatg cgctggaaga cccagaccca
      121 gatgtccaag caacagcacg atatgcttta actcagatga atcgaatgcg tggcttgcca
      181 gaacaacaaa gtctaccgga aaattcagac aaaaattcac ctgaatagaa tagaaatcat
      241 tcgattttag attttttctt caatccaaaa ttggaaacgc atctttgttg ccacctaaaa
      301 tttaaaattg acagtggagc aagtttaaat ctgctgtcag cctaaaaata ttttaactgg
      361 attttgatat tggtatccgg gcctgcgact aaaaatgctg cctcgctaaa tttgggcgct
      421 ctggtgcgaa tctctgggtt gctggaaaat ccaaagcctt cgcttggtat acccaagata
      481 ttgcgattaa gaatgcggtc attattttga tcgtggaaga cagcaacggc gtaactacct
      541 gctttcaaat tgtcaaaagt aatgggtaag ggattgtcag taattttggt acactgcttt
      601 tgtaagacgc gatcgcgatc gctaggaaat ccttcactgc ttgcaaatat actcgcacag
      661 acttgtcctt ctttattttt caagccatct atttccacag taagtttgcc gttaaaattt
      721 gccttggcac tcaatgacca tgccagattt cccagaactg ctaatagtag cagactaact
      781 ctcaatcctt taaccataaa attttcacag aataaaataa gttttgctga aattaagttt
      841 tcacttgcat taataccgcg cagactcata ctgacattat tcagtcaata cttgcaagca
      901 tctggctata tttcatctct tgacacatct gtaaatatga atattcttta gaaatattat
      961 tcagaaataa ttatatgtac tttctaaaac agttaagttg tctttacctt atctttaaaa
     1021 tagtgcaaaa atatctttcc tgttccctac ctcaacgagt aatttcacaa ctgatttagg
     1081 attcctatat caataaaaaa tacggtagaa agttgtaagc aatttataca atatacttta
     1141 actaccgtat aacgactgtt ttgattttta atcttgcttt tattcgctat caaaagctcc
     1201 taattcggga gttttagcac gatttgtctc tttttcttcg atcgcataaa catcaggcca
     1261 tactgacgcg ccgtgttcgt agacatcgat accaatgcga tcggcttcgg gattgacacg
     1321 taggcgtccc aatgctttta gaccaccaaa catcaaaaag gtaaaagcaa cagtgaaaac
     1381 tgcgatcgct accacaccta aaagttgtat agctagcaag tcaaagccgc cacctaaaaa
     1441 taaccctgcc tttttattga gggtcaactc tgcttgacct aagaagccaa cggagagagt
     1501 acccatcatg ccattgatac catgtacggc aaatgccccc accggatcgt caatatggag
     1561 tgactcaatt aaatccactc ctagagtaac caaaatacca cccgttaacc caatcaaaac
     1621 cgaagcccaa ggtgcaacat aagcacaggg ggctgtaatt gctactaatc ctgctagcga
     1681 accattgaga gaataaacta aatcccactt acctgtgcgg gtatattgaa aaattatcgc
     1741 cgaaagcgct ccagccccag cagctaatgt ggtgttgact gtcaccaaac caatcaatcc
     1801 tgtattacca gtgctgaggg ttgaaccagg gttaaatccg taccagccaa accacagaat
     1861 catcgttccc agagtagcta gccctaaatt gtgcgctggt ggtagtgttc cccaagccgg
     1921 acgaccagga cgggggccaa gcaaataagc acctaccaat gctgtccagc caccaacgct
     1981 gtggacaaca gaactaccag caaagtcgtg ataactcaat ttggctaacc agccgccaga
     2041 gttccaagcc cagtggacga tgaggggata gctgattgcc cccataatgg cgctataaat
     2101 taagtcgcca acaaagtcag ttcttcctgc cattgaacca gtagtaattg tactagcggt
     2161 agcagcaaaa gcaaactgga agaagaacaa gctataggta ttaatggcgg ctgtagaacc
     2221 tggcgcaccc aagggataac taccatcaac accaggtagc tgactgagga aaaagttatc
     2281 tatgccaatt aacccgccag cacttgtacc aaaggcaatt ccaaagccaa ttccccacca
     2341 cactaagata gttacagcag cgtcaatgaa gttttctagt aaggcgttaa ctacacctct
     2401 ttgccggatt aaaccggctt ctaacatcgc aaagcctgtt tgcatgaaaa atactaaaaa
     2461 cccagtgatt agtacccaag tagtatcaat ggaaatttgc agtttcgttg tagtttcaga
     2521 taaagactga atagttggag gatctgccgc ttgtacaatt gtcggggcaa aaactgcgaa
     2581 tatcattgaa gcgatcgcta atgccaatag tcgatgccag ggtcgaatac gtttattcat
     2641 tggttatctt tttcctgcta taaaagcaat aattgatatt ggtaatagac ttagcaaaat
     2701 caatcaattg aattaatgct ctttgagatt tctcatgaga gaatattttt gagctttggc
     2761 gatcaagcaa ggctttgaaa aagattcaag gtcggcatct tatttttctc tcctcagaga
     2821 tatacaaaga gcattaggct tgccaaataa ggttttcgcc aacagtttta ggaaataatt
     2881 atctcattgt ctgtgtcagt tcttgatttg attgggaaca cactttttgt aatataaaaa
     2941 actctgatta aagaaaaata tagacactga ttcacagaaa tgacgagact acttccaata
     3001 tggttcggtt aaggtttttt gatgaaaatt atagatcgca aaaatccgat aaatcgccgt
     3061 ctctacaaat gtttcttgtc ttaaccgaac agtattgaga ctacttcctg ttttactttg
     3121 gtaagtatgg cctaaacgga taaattgtgc tgattctcta tttactcaag ctaaaaaact
     3181 gtataagtga acacattttt tggaattttt ggactgacat cgcttttgat gtgacaaaga
     3241 aagcaattag attctttata gataagtatt ttccgagatc gggatcggat atttgggata
     3301 ctattaagtt tttatacaaa aagttaattg cttgttactt taaagtgcag agataagctc
     3361 aagagagcag tcaagataat agacatctcc gaaaaagaat gtagagacgt agcactgcta
     3421 cgtctctaca aggattctgg ataacgcata tttaatttct ggagatattt aatatcatgt
     3481 tcgacttaat gcttatgtca ttgcgttcgc gtagcgtctc gtagagagcg gagcgcagca
     3541 atcccaaggc tttgcaattg ctaccctgcg ggaacgctaa gggcgaacat tccacttcgt
     3601 tgcataccct gcgagaaggc ttacgccaac gcaatgacat atcgtaagtg atttacagaa
     3661 catgatatat tcataactca tctctgcaac gccaaatttc gcatcaaaag taacgcagat
     3721 ttctaaaacc aatccttaga tagaaaattg gtcgagctat ttatacaaca atacagttca
     3781 gaatgagcaa caaaacactt gtagagacgg cgatttatcg cgtctcgaaa acccaaacgt
     3841 attgatttat aggcggcgat cgctatctta cgtcaaatta actctgtaat ggaaaataac
     3901 cgttgtcggt ctattttttg aagcttgatt ttttcagcgt agaaagcctg ataataggat
     3961 tgataccgct ctggttccgc ttctggatcg gtttgttgcc atagctccaa aaagtgacga
     4021 tagcgttttt caagcatcac caaatccata caagcgatcg cagcttgaac cacttgcgga
     4081 gtccgaagta tttctttctg gtttttttca tcgacatgaa ataaatggga aattaacccg
     4141 atctcgctgt caaattctaa aaactggtct tgcaggcggg aaattaaatt tggtagagac
     4201 actaaatttt ttgtctctcc atcaccggat gaaatttcta aaatctgttg ccataaaaat
     4261 cggtggtggg aaaggctaaa ttgcaaatct cgctcctcta gttcgtcaat aatcgcttga
     4321 cgctgttcag gacaatgcaa ataaattcgc aataataacg cctctgcgtg ttctaaaagg
     4381 ctgcgttctg tagggagtgg ggagttggaa atggagagtg gggattggct acctccccat
     4441 gctttctttg ctgatacagg cttagaatat atagccgcag ctggagcaat ttgagttagc
     4501 agattttcga ctcgtagggg tataagtctg gtatctccta agctgagtat ttcagcacaa
     4561 taagaaacat aataatttcg tgtatcgcta ttggctatat tttttagtaa tttgactaat
     4621 tgctgagtta cttgctgaaa atcagtagct tgttttaagt cgcggtcttg aataatttgc
     4681 tgaatctgcc aatctagcca aagtggggca ttttttaaca gttctccata atcttcttgg
     4741 gtatggctat gcaaatattc atcagcatct ttaccatcgg gtaaattgag aatttttagc
     4801 tgaacttcgc ccttgtatgc tagttcggca atttcaccga tcgcccgttc ggtggcatta
     4861 gttccggctt tatcggcatc aaagttgagt actaattgtt tcgattcggt atagcgtaat
     4921 attaaccgga cttgttctaa acttaaggct gtaccgagtg aggcgacagc gttattaata
     4981 ccagcagcgt ggagagcgat cgcatcaaaa tatccctcta ctaccaccgc ttgatcgagt
     5041 tgggaaatcc cacctttggc ttgatctagg gcaaataagg ttttaccttt actaaacagt
     5101 tcggtttctg gtgaatttag atatttaggc tgctcatcag tcagagttct accaccaaag
     5161 gcaataacgc gcccttgaac atcgcggatg ggaatcatga ggcgatcgcg aaatacatca
     5221 taataacctc cgccttcctt gcgtggctta atcaatcccg ctttttccag tatttgtact
     5281 gggtaatgtt tatcttctac taaataacga tagagagttt cccaacctgc gggggcaaaa
     5341 cctaaaccaa attgctgtat agtttcttct ttgaatttgc ggttagattg taaatattga
     5401 agtgcctttt gcccttggga ttgtctcagg gcgtgttgat aaaactgggc tgaggaagca
     5461 agaacttcat ataactgctc ccgcaaagat agctgacgct gtaattcttg gcgttgttcg
     5521 ggttctaggg tttgtacagg tacttggtaa cgccgtgcta aatccagcac cacgtcagca
     5581 aaagagcgtt tccccaactc catgacaaac ttaatggcat ttcccccagc ttgacagccg
     5641 aagcaatagt acatttgttt ggtttggctg acagtgaaac tgggagattt ctcgtcatgg
     5701 aaagggcaca aaccgacaaa atcctttcca cgtttgcgta aaactacgta ctccgatacg
     5761 acatcgacaa tatcagcccg taatttaact tcctcaattg tgtctgggtg caagcggggg
     5821 atttgcatat cttagttact ggggattggt cattggtcat taactttgga gaaataccaa
     5881 aggataaatg agttttggct tctgatggct attatattct tgttgctaga cccagaatga
     5941 tgtatagaat tgcttagact taattttatc agaggaaata ctgaaaatgg ggcgtatttt
     6001 tatatcagcg gctcatggag gcaaagaagc gggaggaata gatcaaggtg cgatcgcagg
     6061 tggtacaact gaagcaaaag aaatgatttt gctgcgggat ttgattgtca cagaactgag
     6121 ggcgcggagt ttggaaattt tggcggttcc tgatgacttg agtgccgccc aaactatcac
     6181 ctggatcaat tcccgcgggc gtcgaggtga tgtcgcctta gaaattgcag ctaatgcggc
     6241 tagtagccct tctgtacggg gggctagcgt cttttacatt gcgaataata gcgatcgcaa
     6301 gagtaatgct gaacagttgc tagtagggtt attgcgccgc gtacctcaat taccaaatcg
     6361 cggagtcaag ccagatacag atagtggatt gggtagttta gcattctgtc gccagacaac
     6421 gctgccagct ttggtgatgc aagtggggtt tctcagcaat ccagaagatc gggctttgct
     6481 gcaaactcgc cgccgtgatt ttgctttggg aattgtcgat ggattggtaa cttggagtcg
     6541 tgtaattgac cccactcctg gaactccagc cgaagcaaat tatccaccta ttaatattaa
     6601 tattaatggg caaagttaca cagaacaagg agttttagtt aatggcaatg cttacattcc
     6661 cattgattta gtagacctgc tgcgaattga tctttcaaaa gcagctaatg tcaataaaat
     6721 tacctatcac aaaatagtgt atgtcaaagc gatcgaacta cgagatttta atgttgcagt
     6781 cacttgggat gcggcgacgc gtactgttag cttgcggtcg aatttggtag tttgtcccgg
     6841 tcaattttcg cgggtgatgt caaacggtac tacttccgaa atacagttac aattattcct
     6901 gaaaaataat aatcaaaatg ctttagccaa gtttcctgac attccaaaac tttatcgtga
     6961 agaagcaggt atagagggag tgaactatga tattgccttt tgccaaatgt gtgtagaaac
     7021 tggattttta cagtttggtg gtgatattaa acctgagcaa aataactttg ctggcttggg
     7081 tgcgatcggt ggtggtgccg aggctgcatc ttttccaagt gccagaattg gagtgagggc
     7141 gcacatccaa catttgaaag cttacgccag tttagaacct ttggtacaag aagtagtaga
     7201 tccaagattt cgctttgtta cacgggggat tgcaccatta attgatcagc tagcagggcg
     7261 atggtcagca gatttagatt atggtacaaa gatttcagca atgctcaaac gattatatga
     7321 atcagcagga cttctttgag ttatgactca atacagttca taatgagcaa caaaacactt
     7381 gtagagacgg cgattgatcg catctcgaaa acccaaaatt gttgccagta aaccttaacc
     7441 caagcgtatt aatttatgat atatctccct tatattcttc taacaattgc ggaatgtgat
     7501 catacccatc cacaccgata actgcaatca ttttcgggcg atgttgctgt aataactttt
     7561 ggaaagcttc tactcctatt tgtccttgta aaattgtcag taatcctgcc ggctgacgcc
     7621 actcacgaga agcaatttgc tgtaaaagat acattcccaa gcagccggtg taaacagttt
     7681 tttcggaatt ttgcaaatga taataggctt ctgctaaata agctaagttc cgcccttgca
     7741 aatacaaatc accggaaact tgcgccgttt taaaaccatc ttcgagatat ttaattgccg
     7801 tttgatgttc tccgattact aaataggcaa ttcctaagct gctcacacat aaggctttac
     7861 tttgaatatc gcctaatttt tctgataatt ttagaccttg ttctaaatag ttaattgcag
     7921 cttcataggt ttcaggttct aagttttcta gttcctgagc ctgcataact tcgctgtaac
     7981 ctaaatttac cagcgcgttt gcttctccgg tgcgatcgcc tgcttgccga ctcagtatta
     8041 atgctcgttg actataatta attgcctcag cataattttg ctgttgcacg taggtacggc
     8101 tgaggtggtt gagattggca atttcacagg cgcgatcgcc tgcatttctg gcaatctcaa
     8161 gtgcctgctg atgaaaatca attgagcgct gatattgtcc caaagcacgt tgagaatagc
     8221 ctaaaagtgt caaaattcgt gccttttctt gggttccctc gcctcgtcgc agtggttcat
     8281 ccaaataatc tagggcatct cgtaaataag tgccagtaaa agaggcaaaa atcccgccgt
     8341 aaaagggaaa atatggacgc tgggcaaagg ttcgcaatat ctggagcata atttgagaac
     8401 aggcatcgct atatactgtc ccaatgctgc taaaaccact tgctaactga ctccaaatca
     8461 ctgcaaaggt caaaaaagtg gaaatagata actttggccc agctttcaca tcgtaagctt
     8521 gttggtcaaa ccagttaatt agtccccgtt gcaagaactg taaaatcaat gccatttcta
     8581 cccaatctct gagggtgata ccccgttgtc gctgggcaaa ctcaattgct gattcttctc
     8641 tagctaaggt gcgaagcagt gtttggggta actcgctact gagttgttta gcccaacttg
     8701 cccaagggcc acgttctcct ggtacgccgc caaatcccag agattctttt tgttcgtaca
     8761 tccaactgag caagttgtct tgcaatcgct gccaagaagc taaaccacgg gtaattcctt
     8821 cggaaaattg ttgtaaatca gaatcagctt gagcaaattg ctgcaatgct tttgacaact
     8881 gctgtagctg ttgcaaattc agcggatact tctgattggg gtcagtaacc cggataaatg
     8941 tcgccagacg ctcgttagcg gtagctgtgg taatttctgt aactgcggag gcgatcgctt
     9001 ctgtggcttt attttgctct tgccagcgtt gccattgact ttgaatcgtc ttaatggctc
     9061 tcaaactgcg agtcgccttg gctttcttga gttcgtcttt ttcactatcg acttggcttt
     9121 ggaaagcatt caggcgatcg ctcaaagcta gctcaaacac ttcccctgtc ccggaagtga
     9181 taccttttag cagcatttga tacacctgtt cgacagagct aattttgccc ttgagggtgg
     9241 tttcgacaat ttcatcgatt aaggcaagat agcgatcgct taatggcaga gagtctggca
     9301 ctttggctac taggagaatg tcacatcaat tctaattcta gtcttggcag caacaatggg
     9361 aaaaataatt agcggcaaaa aaattttcgg ttattgcaaa tatctaccct agttttcccc
     9421 cattactctc taaattcaaa tcagaagagc agagaacacc gcccaaaacc agcgcagaac
     9481 ctctgctgct taattaagtc aacaaaaacg gagagtatag ataatgttac accaaatcaa
     9541 agaactgctt caaaacgccc aattacaaca acaagtcaaa gcagccgcta accaagcaga
     9601 agcagtcaaa gtgttagcga tcgctagtgc agaaaagggt tataacttca cagtcgaagc
     9661 catctctcaa atgctatcag agttgacctt tgtggattct aacgaactga gtgaagaaga
     9721 attactcagt gttagcggtg ggatgatgtc tgaaagtgcg gccaagctat gtcatacaga
     9781 ttcctgtggt ggtggacacg ggggatgctg ctaaaaaagg tagcttctct ttctttttgg
     9841 cattagacat ctaaagaatt ggtgtaggga caattcatga attgtcccta taaagggttt
     9901 caggtaatgc atctgttcga taattccact ttttattcaa caaatttaaa actaattttt
     9961 ctgcattcta tcttaacgat taatactgag aaatctagct atggttcaac aagttgttcg
    10021 cttatcccaa cagaaaacat cagacgattt aagagcgatc gcagctaatg ctagctttct
    10081 ctgggaacgc cttgatgaaa gcagatttgc gatcgatgtc gatcgagtta atgaacaaga
    10141 aattaaccat cgtagacatc gctggtgcga agttgcagca gaaggtaaat ggaatacgtt
    10201 gcacaaacgc ttacagtggg aggaactaga ccttgatact gttagttcga gattgggaac
    10261 tatcgagttg cttgccgatc aacctttgcc agagtgggca gaaactttac agcaaatcat
    10321 ccaaaccgca acaggattta attctgcaac cgaagtattt ttaccaatcg attcacaaaa
    10381 tccgatcgcc tttgaagata ttcttttgcc tgctatctta gtagccagac agcaattatt
    10441 gattcgctgc aacagtcaat tcacccaaga ttgtcttccc ttatcgattc tttcttacga
    10501 cgcttacagt tctctagaac gtagtctgtt acaacgacta gcaggaattt gtacgaagac
    10561 attggatttt gaattctctc aggtgcgtcc ctttggtcaa agcttgctcg gtttgctagg
    10621 gctggagaca gaaaacaata acattcacta caccaagttc gtcaatcaac tcctagaaga
    10681 tggaatgttg acgttcttcc aaaagtatcc agttctcggt cgcttaatgg caacagcagt
    10741 caacttttgg gttgagttta ctgctgaatt tcttgaacgt ttagttgcag ataggacaga
    10801 tattcaacga acttttgatc aaacaatcgt cccattttct caaaacaaag ttaccgaaat
    10861 tcaaacctct ctctccgacc cacacaagcg cggacggacg gtgattttac tcacctttga
    10921 atctggactt aaacttgtct ataaacccaa agacttagga ttggaagttg tctttaatca
    10981 atttttgggt tggtgcaatc aacacagcaa tcttttagac tttaaaatca ttcaggtatt
    11041 gaagcgtaaa ggttacggtt gggtggaata tgttgaacag ttaccttgtg ttgatgaagc
    11101 cgctgcaaga cgattttatc aacgttctgg gatgctgttg tgtgtgcttt atgccctcag
    11161 agctacagat tgccattatg aaaacttaat tgccaatggc gaacatttgg tgttgattga
    11221 catggaaaca ctgctgcacc atgaaccgaa tctgattgaa gactcacccc ttacccaaga
    11281 tttggaagca accgccacac gacaattttg ggattccgta ctccgcaccg gacttttacc
    11341 gcgttgggac tttagtggcg atcgcagtgt ggcttatgat attagcggtc tagggagtac
    11401 agatcctcga ttatctcccc gcaaagtgcc gcgctggcag aacattaata cagataatat
    11461 gcagctgtta tctgagtctg taaccttgcc cattgcaaaa aatgtcccat gcttgggtga
    11521 agttcccctg tctccaaacg attatcaact acaaatcacc actggatttg agcagatgta
    11581 tcgctttttg atggcgcaca aagatttctt actttcaccc caaagtttgc tatctgcgat
    11641 gcaaaatcag caggtgcgct ttatcttccg caacacccgg atttatggca ttatcctcca
    11701 aaaaactttg tcacccgatt acctcaaaca cggggtagat tacagtattc aactcgatgt
    11761 tctcagtcgt gcctttctag ttgctcagga aaaaccaaat gcctttcctg ttttgagtgc
    11821 ggaacttcga gcgatggaac aattagatgt tcccttcttc actgctagcg ctgtggttga
    11881 tgaactgagt ttaaacggtt cttctgccat tcctaactac ttcaagcaac ccagttacca
    11941 agacttgctc aatcagttgc aatctctcga tgaaaccgac ctggctcgac aagtagcgat
    12001 tattcaaggc tcctttgatg ctaaaatcgc aaccacccat agccgcaaag gtgggcaatg
    12061 gaaaagcgaa tccttaccat tcctgagttc agaacaattg attgccgaag ccaaagaaat
    12121 cgctaacgaa cttgaaacca gagctatttc cgaccctgac gggagcgtta actggattgg
    12181 tttagacttt gtgcctcgcg ctgaacgata tcaactgcaa gtattgaata attgtctctc
    12241 ggatggacgc tctggtgtgg ccttgttttt agctgcactc agtcaagtca caggtgattc
    12301 ccgttaccgc gatttagcat ttaggacatt acaatctctg cgtcgccaaa ttcacaccgt
    12361 tgatccagaa acttggcaac gaatggctag ttttatgggt gttggcggtg caacaggttt
    12421 aggatcaatg atttatagcc tggtgaaaat tagtcaattc ttcaacgata taacgctatt
    12481 acaagatgcc caagtattag ccgatttgat gacaccagaa ctaattgctg ccgatgaaca
    12541 cttggatatt atgagcggag cagctggggc aattttaggg ttattgtcgc tgcatcaagc
    12601 cacaggagaa gcaaccgttt tagaaaaagc gatcgcctgt ggacaacatt taatcaaccg
    12661 tcaagttagc cacaacggtg cgcctaaagc ttggcatacc ttttgggaca agcctttgac
    12721 tggtttctct catggagccg caggcatttc ttacgccttg ctcagactct acgccgttac
    12781 cttggagagt aagtatttag aagcaggttt agcaggaatt gagtatgagc gtagcgtctt
    12841 ttgcgaatct actgccaact ggcccgactt ccgcagaatg ggacaaccag gacaacctga
    12901 ctttgcaaat aagtggtgtc acggtgcagc tggcattgct ttgggacgct taggcagttt
    12961 gagaatcgtg gaaacgccgg aaattcaaca agaaattgaa attgctctcc agactactca
    13021 gaattttggc ttacaagcga tcgatcactt gtgctgtggt aacttgggta gggcagaagt
    13081 gctattagtt ggtgcaaaaa tctgttcccg tcctgactgg catcacattg ctcaccagaa
    13141 tgtaacaaat gttgtagcta gagccaaacg aactggagct tatcaactat tccccaactt
    13201 acccaattct gtatttaatc ctggcttttt acccggtata tctggaattg gttatcaatt
    13261 gctgcgtctg gctaacaata acttgccttc aatattgttg tgggattgaa cttgttgttt
    13321 atacccaaaa acagtttttg actacaccct attaagtcta taagtgcttt cccaagcggt
    13381 cggagttgta tcaaatactc ttgcataatt ccccaatcaa cctctgatag atgtacaagg
    13441 tcaacaacgg gatatataca gcccagccag gctgggacgc ttgtacgaaa tgggggatac
    13501 ccaacggaac aaaactattt gatgcctttg ggggttgagt gcgatcgccg ctctactact
    13561 tcttctttga tacagggtat cagttaagtc gagggggagt attatcgcct cttccaatta
    13621 gaactggacg tgtaatttta gctgcatcca gctcccgata aactcccaaa gcccatgtgg
    13681 aatcaccgtg ccaatacggg gattttgtac gccaatactg ctttgaaaac ttgagattta
    13741 ataagaggtt taaatttatg tttcgcaaat ttccatcctt aatagcttct cgcgtatttg
    13801 cagtcgggtt gctattagta tttgggttca gccaggttgc gacagcgcag cgttcatcaa
    13861 gttctgatga aactagtttt gagttatttc ctaacacgca gttcattaat tgtatggcag
    13921 ccactcctgg agtcacgcct cgggttcaag ccatcgtcaa gcgtggtaat cttaatgaca
    13981 atctgacttt gaggctgaca aatttcaagc cgggtttgaa gtttgacctg tttactgtag
    14041 agaatagtcc tcagcaggca ttcggtaccc caaaccccaa attcaagaac tttggtctgg
    14101 cttggtacca atctgacgtt gagcctggac ttgtgacaat taaaactatc ctgctagatc
    14161 agattttcgg ttttgatccg caagtgaact taccacctac taacactttc catatagggt
    14221 tttggtttaa caacccacaa gatgctgccg cgtgtggctt tgatgttcgc aaacctaccc
    14281 cctttaatgg tgaacacaag gctggtccat tagcatttat tagccgacct aattctctaa
    14341 ccaacctcgg gccgctttgc atcaaaccta acacctcaaa aaacccgccg acttgcaacc
    14401 cttaacctgt tgattcaaga caatgcccgt ttccgggggg ttcaactcag ttcaaacaga
    14461 ttgaacgttg ttgaatgcta ggaagtgcag acatctttta acattgcacc gagcatcgtt
    14521 tgccacttgt tttaaaactt aaccgccttg gggtacaccc gtggcggttg gggcagatat
    14581 agctctcgcc aacacaaagt gcaaactaaa ctctatttgg cattgtttca agatggacgt
    14641 atttatcaat tgataactat ttgtaataac tgtatagcta ccaccaagaa taaatgaggc
    14701 tactgccccc agttcgtcta cctaacaagc attacaggtc tagagaatac cttatacgaa
    14761 gaaaggtgcg atcgctcctc aatgccgcac tagatcgcaa agcttgtcta tagggctctc
    14821 gtgtcgccca ccccacaaga gttaattgaa tattttttta ttttgaagtc cctaattcaa
    14881 ttcagattaa cgcgactgac caaaatagtt ttatgattct ctacgaaagc atattgtgaa
    14941 attaccaaaa aattctcaag ctcattctga aacatggtga atggtgattc accaaaacct
    15001 tcttccaagg tcaaacaaag tgcagggaga tgaacaagta tggctgaaca tgtatttcat
    15061 aaccaactgg gtttagagga acaaaccgaa aaacttggaa agcaagcatt gagcttgggt
    15121 ttgattccca gctttgtggt gcattacttt cccgatacct gggtatttta tatcccaaat
    15181 gaaagtcaat ccgaaccgct gacaccagaa gaggcatact ttcgtttaaa gcaactggtt
    15241 aaacagtaga tattttgaca acagattttt gaaaataacg gctaggcact gcaattgttg
    15301 agtaacagta attatggcga aaccagcaat tttaaccgtc gatgacgatc cagaggtgct
    15361 gcaagcagtg tcacgagact tacggcatca gtatggcgat cgcttccgta ttgttcgggc
    15421 agattccggt attactgctt tagatgtggt gcagcaactc aaattacgaa acgaagctgt
    15481 tgccctattc ttggtagatc aacgtatgcc ccagatggga ggtgtggagt ttctagaaca
    15541 ggcaaaagac atttttccca atgcgaaacg tgccttgttg acagcctatg cagatacgga
    15601 tgctgcgatt aaatcaatta atagtgccag acttgattat tacttactca agccctggaa
    15661 tccaccagaa gagaagttat atccggtttt agatgatttg ctagatgact ggctagctgg
    15721 attccgccca ccttttgaag ggattcgagt cattggtaat cgctggtcgc ctttttcaca
    15781 tcaggtgaaa gactttttag cacgtaacca gattccattt aagtggttag atattgaact
    15841 ggaaccagag gcagcaaaat tggtggaata cgcccaagct gattgtagac aacaattgcc
    15901 cttggtgctg tttcccgatg gttcccggtt aattcaacca tctaatttag agattgctgc
    15961 caaaattgga ctgcaaactc aggcagagcg tcccttttat gatttggcga ttgtgggtgc
    16021 tggccctgcg ggactggctg ccgccgtcta tggcgcttct gagggattga gtactgtctt
    16081 aattgagcgg gaagcgccag gaggacaagc tggcacgagt tcgcggattg agaactattt
    16141 gggatttcct attggcttga gtggcaacga tttggcaagg cggggagtga cccaggcgcg
    16201 gcgatttggc gtagagattc tcacacctca agtagtaact ggagtgaggc tggaagatcc
    16261 ttatcggatt ctgcaattgg cagatggtag cgagattagt tgccatgcgc ttttagttgc
    16321 aactggggtt tcctaccgtt ggctaaatgt accaggagcc gaaaagctta caggggcagg
    16381 aatttactac ggtgctgcca tgactgaagc gatcgcctgc accaacgaag aggtttactt
    16441 ggtaggcggg gcaaactctg ctggacaggc agcaatgcac ttttgtaaat atgccagaaa
    16501 agtgattatg ttggtgcggg gtgagtcact agcatcaagt atgtcccaat acttaattga
    16561 ccaaattgcc gcaactgaaa atatccaagt ttgcacaagt tgtagcgtcc tggaagtaaa
    16621 gggagaggaa catttagaag caattgtgat tgcccacgcc aagacaggac aaactgaaac
    16681 cgtgtcagcg cgatcgctgt ttattttcat cggtgctagc cctaaaacag attggcttga
    16741 tggcgttatt caacgtgatg ctcaggggtt tgtcatcacc gggccagact taatacataa
    16801 tggcaaatct gccccaggtt ggaatttgga acgttctcct tttttgctag aaaccaacat
    16861 tccaggcatc ttcgcagctg gagatgtccg ctacggctca attaagcgcg tggcatccgg
    16921 tgtgggagaa ggttcgatcg ccattcaatt cgttcaccgc tacctgagta atgtttagct
    16981 agaacgggaa aaactatata tttgcaaacc tctcccctgc ctcccctgct ccctgcccct
    17041 ctatcccctc aaggaggttc attgatgtta tgtgttgaag aattaatcaa cttagaccca
    17101 tttcaacaac ttcctaaaga gcggttgcag tgggtttgcg atcgcgctca aacagttgaa
    17161 ctttcggccg gagcagtgtt gtcctatgag ggagaccctg tatgtcgctt atttatcttg
    17221 gttaaaggta aaatcaacat cacccgccgt agtgaaggcg tggaaattcc catcgggcaa
    17281 cacgaagccc catctttttt tggtgaaatt cctgtactca cggatgaacc tgcacctgtg
    17341 acgatgaggg cattgacaaa ttgccatatc tatgaaatga agggagatga ctttcgtaaa
    17401 ctgctgcatg aatgtcgtga ttttgagcgg atggtcttcc gaattatgca gcgtcgtgtc
    17461 cgggggctag agtctttcat tcgtgggcgg gaaaagatgg cagctttagg gacacttgct
    17521 gccggtttag ctcatgaact caacaaccca gccgccgccc tggttcggac tttaggagaa
    17581 atgcccgccg ccatcctaga gttacaacga atgaacttag tttatgggca acgcaatgtt
    17641 gacgaagccc atactcaaca ttggttgaga gtacgggatc agggctatga tgcgattttg
    17701 aataatcgtg tagatccggt gacactaagc gatcgcgaag acatattgct ggaatggtta
    17761 gaagactatg gtgtaaaaca agcctggaaa ttagcagaac ctttagcgga aggtggtgtt
    17821 gaggttgaaa ccttagagca actcatggaa cgttggcgca acgacgacac agaattgcga
    17881 gaaatgggat tgcactggtt agcgctttcc tttgaagtca tgtcgatgat taaacatggt
    17941 ttgcgaggat ctgagaggat ttccgaactt gtgcaagcga tgaagtctta ttcttacctc
    18001 gatcaaggta ttcagcaaga agtagatata catcaaggct tggaagatac cttgcgattg
    18061 tttgcccata aactcaagag tggtgtgcaa gtgcaacgca attacgatcg gggtcttcca
    18121 aaaattcttg cctatggcag tgaattaaat caagtgtgga caaacttaat tgacaacgcc
    18181 attgatgcaa tggatggtaa aggattgctg gaaattaaaa cttggtattg cgatcgctat
    18241 gctcatattg acattatcga ctctggctgt ggaattccac tggaaattaa aacgcgcatt
    18301 tttgaaccct tcttcacgac caaatcagta gggcatggat cgggattggg tttagaaact
    18361 actcgccgga ttgtagaaaa tcgccatcac ggtacactct catttgaatc gcagccaggt
    18421 agaacttgtt tcaccatctg cttacctttg acatcttgaa ggagaattca gaagtcagaa
    18481 tttagaagtc agaattcagg agtcagaatt gtctcgttcc cagtctcaga ctgggaatgt
    18541 ctatctttga ggctccgcct ctcctgctgg cggcagagca acttttgagt tgcatttcca
    18601 gcctccggct ggaaacgaga tttgaagatg gtcttagctt aagttgacac caatggcaat
    18661 aactctcttt cctcctctgc cccctgcccc ctcaacagat aactttatta accaaaccgt
    18721 attaagttct cccctagttc tccccgatcg cactttaatc ttaaaagtct agaagattta
    18781 aggttttggg tgctttcagc aagaaggaga acaatgcaac taaaacacag ccacatcttt
    18841 cgccaagaag ccctagaacg cttatcttca ccagaacaac tcgatcaagc gatcaatgtg
    18901 gtcaagcctc aagcttggtt gactttatct gctatgagtt ttgtggttgc tgtggctggt
    18961 gtttggagtg tgtttggcag aattcccctg actgtaactg gacaaggtat cttgatcaaa
    19021 ccgcaccatg ttgtggaatt tcaagcaccc agttcaggcc cattattaac tctcaaggtg
    19081 aaggcgggag atattattaa acaaggtgat gtgctaggta ttatcgacca atcagcgcta
    19141 aaacagcaac tacagcaaga gcaaacaaag ttacagcaat tgcaaactca gaatcaagaa
    19201 acagacaggt tacaaaagct gctgattgac caacaaatca tcacccttgg acagcagaga
    19261 atggatctgg aaaataatct gcgccgagag gaagttgcac cgaagttacg cgatcaaaca
    19321 caaagagcga tcgcccaaaa acgtcagagc attaattccc gcaaacaaca aattaattat
    19381 ttacttaaaa ccctcaaagg gcgagttgat aaccgtcgtc acctttttga gcagcatgtc
    19441 atcagccaag atatgttggt gcaagctgaa caagaatatt ttaatactca aagcgaacta
    19501 tcagatattg atgtgcaact aaaggatctc gaaatccaag aaaccacaac gcaacgagaa
    19561 tatctggaaa acctgaataa gattgacgaa attaaaacca aaattaaaga cctgaatact
    19621 caaaatacta aattacgcga acaagattta aagcaatcaa ttgacaaaac taatcaaatt
    19681 cgagaagtaa aacggcgaat tgcccaatta gaattacaac tatctcaaga aagtagaatc
    19741 attagcaaat acaatggtca tattttggaa gtgagtgttg tgcctggtca aatgatgaat
    19801 cctggtactc gcctggggtc aatcgaagct gaagaggcaa attcaaaact tgtgagcctt
    19861 gtctactttg ctaataaaga tggtaagcaa atcaagccag gaatggctgt acaagtgact
    19921 cccagctttg ccaaacgtga gcgcgaaggt ggtattattg gtgcgatcgc agatatttct
    19981 gcatttccag taactacaca agatattaca gcgatcgttg gtaacaaaga aatagccgcc
    20041 agtcttgcag ggagaggtga aggtcaggta caagcttttg tccaactcca agaaaacccg
    20101 acatcagtca gtggttacaa atggtcatct tctgatgggc cagctttaaa aatatcctct
    20161 ggcacaatca cttctgttca agtgaaagta ggagaaaaag caccgatttc ttatattatt
    20221 cctatgctgc gttcttggac ggggatttat taaattgggg atgagagaat agaatgtcac
    20281 taggataagg ggaaagggga agggggaatg gaatggaaag gaaaaaaatt gaaacttttg
    20341 aggatttaag agtatggcaa aaaggtattg acttagttaa ggaaatatac ttaataacta
    20401 agtatggtga actcaataga gactttggtt taaggatcaa ttaagacgtg ctagcgtatc
    20461 aatacctaca aatattgctg aaggatttga acgatcttct cgcaaagaat acttaaactt
    20521 tctaaatatc gccaaagggt ctgccgggga agttcgcagt cttttaagag tagccttaga
    20581 agtgggctat ttagaccaac caatttatac acaacttcat aatcaagcta tggagttgag
    20641 ccgtatgcta tctaatcaaa ttcaatccat aaatcactca ttaaaataat aaaaccttcc
    20701 ccattcccca ttcccccttc ccccttcccc atgtcccatg accaattccc aattcccaag
    20761 tcccaaattt aaacccaatc gcgtccgcac ttctacactt ttgcaaatgg aagcggtcga
    20821 atgtggtgcg gctgctttgg gaataattct tagctattac gggcggattg tgccactggc
    20881 taaactgcgt gaagaatgcg gtgtctcgcg ggatgggagt aaagctttta atattctcaa
    20941 agctgccaaa aattatggac tcaatgctaa aggtttaaaa ctgtctctag aacaggtgac
    21001 aactacccgc cttccctaca ttgtcttttg gaattttaac cattttcttg tggtagaagg
    21061 atatagcaaa aaacgcgtct acctcaatga tcctgccaat ggtcggagaa cagtgagttg
    21121 ggaggaattc gatcgcgcat acacgggtgt tgtgctggtg atggaaccgg gcgcagactt
    21181 taagaaggga ggcaaaaaaa atcacattgt ctcagcttta agtagtcgct tgcaaaactc
    21241 acgagttacc attttatttt gtctgctggc tgggttattg ctaacattgc ctcggttagc
    21301 tgtaccagcc ttttctcagg tatttatcga tgagatttta gtccaagata gacaagattg
    21361 gttacgacct ctgctgttag gaatgctgtt aactacttta ttacgggcat tccttgctag
    21421 actgcggctt acctgcctgc ggcgattgat ggttaagttg tcagtcagca catcaggact
    21481 atttctctgg catatcctgc gattgcccat cgggttttac gaccagcgct ttgctgggga
    21541 aattagtagc cggatgaaac tgaatgatcg ggtggcagaa gtactttcag ggtctttagc
    21601 aaccacaatc attgatgcag tgatgatggt cttttacctg ctaattatga ttcagtatga
    21661 ccaattattg agtgcgatcg cagttagttt tgctgtaatc aacattctcg ctctgttctt
    21721 tttgtcgcaa actcgtgtag atgccaatat gcgcctagct caagaatatg gcaaggtggg
    21781 tggagtcacg gttagtggca tccaaactat agaaactatc aaagcttctg gactggagtc
    21841 agatttattt gctcggtttg cgggttatta cgccaaagca ctcaacgccc aacaagaatt
    21901 aggcttgcaa actcaaattc tcaccacatt accaacaatt ttgacagcct taaccactgc
    21961 ttctattttg ctagttggtg gtttacaggt aatgaagggc aatctcagca ttgggatgct
    22021 agttgcctac caaagtttaa cactgagctt cttagagcca gtcaatagcc tcgtcaattt
    22081 tggcagtaca ctccaaactt tagaagctga cttaaaccgc cttgatgatg tattgcaaaa
    22141 tcccgttgat ttggaagtgg aggggagagg gagcagggga gtaggggagg taggggaggt
    22201 aggggatgca gggggagaaa ttactttctc gtctctttgg caattacagg gcaatgttga
    22261 gttacggaat gttacttttg gctatagtcg tgtggaatct ccgttgattg agaatttgag
    22321 cttgactgtc aagccagggc aaagaatagc gcttgtaggg ggaagtggtt ctggtaaatc
    22381 tacagttgct aaattaattt gcgggcttta tcaaccttgg cagggggaaa tctgctttga
    22441 tggtgtagag cgatcgcaaa tcaagcgttc tgttctggct aactcgttgg caatggttga
    22501 acaagatatc tttttatttg ccgggactgt gcgagaaaac attactcttt gggatgcaac
    22561 agtgctagaa gctgatttgg tgcaggcttg ccaggatgca gctattcatg atgcgatcgg
    22621 atatctaccg ggaaaatatg acttcgattt aattgaaggc ggtatgaata ttagtggtgg
    22681 ccaacgccag cgcttagaaa ttgcccgcgc tttagtgaga aatcccaccg tgttagtact
    22741 tgatgaagca accagtgccc tggatgcaga aacagagttg ataattaacc gtaacttaca
    22801 acagcgtggt tgttcttgta ttgtagtagc ccaccgtctc agcacaattc gcgattgcca
    22861 tgaaattatc gtgctagagc aaggtaaaat cgtgcagcgt ggcactcatg aagaattatg
    22921 gcagcaaggc gggacttatc ttcacttact tcacgcagca gaagcataat atcaagtttg
    22981 agaacattta ttggaagtat tcgtcctcaa gtatagacat aattactaac gaagaatatt
    23041 tatctttttg cctcaaagct tctcgcaaaa ctccttcctc ctgaaagccg accgattgat
    23101 aaacatgtct agcacgttga ttgtgttcaa agacatctaa ccaacaacga tgagcattat
    23161 actcttcaaa aacctttttg aggataattc ttaacgcacg tttgccgtat cctagtcctg
    23221 gttcagcaac gataattcga gttaattcaa tactcctgtt tggtgattgt aacccagaca
    23281 aaatagcgta gccttgcgtc tctcctgaa
//
