LOCUS       NZ_CP040272            20831 bp    DNA     circular CON 31-AUG-2024
DEFINITION  Nostoc sp. C052 chromosome, complete genome.
ACCESSION   NZ_CP040272
VERSION     NZ_CP040272.1
KEYWORDS    RefSeq.
SOURCE      Nostoc sp. C052
  ORGANISM  Nostoc sp. C052
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
            Nostoc.
REFERENCE   1  (bases 1 to 7828336)
  AUTHORS   Li,F.-W.
  TITLE     Complete genomes of symbiotic cyanobacteria from bryophytes provide
            new insights into the evolution of Vanadium-type nitrogenase
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7828336)
  AUTHORS   Li,F.-W.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2019) Boyce Thompson Institute, Boyce Thompson
            Institute, 533 Tower Rd, Ithaca, NY 14853, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.4.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 84.0x
            Sequencing Technology             :: Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013393905.1-RS_2024_08_31
            Annotation Date                   :: 08/31/2024 08:18:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,527
            CDSs (total)                      :: 8,409
            Genes (coding)                    :: 8,174
            CDSs (with protein)               :: 8,174
            Genes (RNA)                       :: 118
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 104
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 235
            CDSs (without protein)            :: 235
            Pseudo Genes (ambiguous residues) :: 0 of 235
            Pseudo Genes (frameshifted)       :: 84 of 235
            Pseudo Genes (incomplete)         :: 168 of 235
            Pseudo Genes (internal stop)      :: 38 of 235
            Pseudo Genes (multiple problems)  :: 50 of 235
            CRISPR Arrays                     :: 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:15:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6082245
            Orig. end                         :: 6103076
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040272.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Fay-Wei Li, Boyce Thompson
            Institute, 533 Tower Rd., Ithaca, NY 14853, USA.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20831
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="20"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20831
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20831
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10831](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10831)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    384..397
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.54"
                     /tool="antismash"
     gene            complement(575..901)
                     /locus_tag="FD723_RS43915"
                     /old_locus_tag="FD723_25075"
     CDS             complement(575..901)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020650.5"
                     /locus_tag="FD723_RS43915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_25075"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_306297028.1"
                     /transl_table=11
                     /translation="MTHLFISGRAWKPTVKLFPASVDTNAPVAAIAAGQPIPVIALVER
                     SPKTHGLLVLLNSPIKKVTDLKGKKIGNPSGKSYFFAVQVLERAGLKDTDVQRVQIEND
                     AGTA"
     misc_feature    complement(942..956)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.38"
                     /tool="antismash"
     gene            970..1680
                     /locus_tag="FD723_RS25160"
                     /old_locus_tag="FD723_25080"
     CDS             970..1680
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012409855.1"
                     /locus_tag="FD723_RS25160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_25080"
                     /product="TIGR04283 family arsenosugar biosynthesis
                     glycosyltransferase"
                     /protein_id="WP_179067803.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.4e-19,
                     bitscore: 68.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQTIGAAKISIIIPAINEAGNIKKAIATTQGSINIEVIVVDGGS
                     SDDTVAIAQSLNVKVISSSPGRAVQMNAGAVAASGEILLFLHADTRLPTGFDEMIRTAL
                     QQPGTVAGAFKLRIDASLLSLRWVEWGVNVRSHFYQMPYGDQAIFLTKEIFQQIGCFPE
                     LPIMEDFELMRRLKSIGHIVIIATPVVTSARRWLQKGVFKTTLLNQIVITAYLLGISPE
                     RIRRWYRRDKFKRV"
     gene            complement(1741..4245)
                     /gene="hetF"
                     /locus_tag="FD723_RS25165"
                     /old_locus_tag="FD723_25085"
     CDS             complement(1741..4245)
                     /codon_start=1
                     /gene="hetF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017317679.1"
                     /locus_tag="FD723_RS25165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_25085"
                     /product="cell division protein HetF"
                     /protein_id="WP_179067804.1"
                     /transl_table=11
                     /translation="MTQEFHISVTPVGQNDYLVRTEQVAPGVPLAEELVTWPIADWLMA
                     AGHLMNDPLKSVLQGDPFTSGGHESDIARNSVNLVALGQQFYNALFQGTLRDSWITAQG
                     IAQNHQQVLRLRLGLKDTRLARLPWEVMHAGDRPLATGPYVAFSRFQSGISGASPLRSQ
                     NMPTPLEQGGVKVLMVIASPSDQVRLDLQKQEAIKLQAELQRQTSRLAEGSNRLPEIEL
                     TVLDQPGREELTQALEQGRYHVLHYSGHSNLGSNGGEIYLVSRRTGLTEILTGDDLAGL
                     LVNNNIQMAVFNSCLGAYTAASNPSGDTGERNLAESLVKRGIRSVLAMSERIPDEVALT
                     LTQLFYRNLSQGYPVDLCVSRVRQGLISAYGSHQMYWALPILYLQPEFDGFLSQETELS
                     ANTESLNQYSSPLGATSTMYSAMGDDSEIPLGMEDMIPSGLTRDSSGLDWLGEDTWGDL
                     VDEIEYDDPSYEEDSAIVSDLFRQLDNQKAVIEPDRQIRENSLHQNQISEEMTSLQEEA
                     DLWGEVPPPPPATPGNLEGNWQNSNFLPQPLSARNRTRRRRLWPIVGVVGISALAAAIA
                     LNWWWQNRNQSTLPNIPVIPTQSLPDSRPIQKQPNIDLGIEATGIVTATATEKLSQGEL
                     QGGLLAVEELLNRGALAAAETALKLIPSKQADDPSVNFYKGRLAWQSIQTGDNNYSIDD
                     ARRYWETAAKAKPESLLYNNALGFAYYTEGNLNRANDSWFKALNLALKEQNTDSTSTKT
                     EVPQDALTSYAGLALGLYKSALSQSSGKQIQYLNEAMKLRQMVLKSDRENFQVDKLAKN
                     WLWTEKAIEDWRSLLQEKGEVN"
     misc_feature    complement(4645..4659)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.93"
                     /tool="antismash"
     misc_feature    complement(4998..5011)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.89"
                     /tool="antismash"
     misc_feature    complement(4999..5012)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.97"
                     /tool="antismash"
     misc_feature    complement(5000..5013)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.08"
                     /tool="antismash"
     misc_feature    complement(5220..5233)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.89"
                     /tool="antismash"
     misc_feature    complement(5221..5234)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.97"
                     /tool="antismash"
     misc_feature    complement(5222..5235)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.08"
                     /tool="antismash"
     misc_feature    complement(5442..5455)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.89"
                     /tool="antismash"
     misc_feature    complement(5443..5456)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.97"
                     /tool="antismash"
     misc_feature    complement(5444..5457)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.08"
                     /tool="antismash"
     gene            5601..5822
                     /locus_tag="FD723_RS25170"
                     /old_locus_tag="FD723_25090"
     CDS             5601..5822
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FD723_RS25170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FD723_25090"
                     /product="hypothetical protein"
                     /protein_id="WP_179067805.1"
                     /transl_table=11
                     /translation="MQSSLRDAALWRKPLAEKAVSVVRYRLSILGPDDRSAPLLLLLLL
                     VDLEYPPVVGIEDNLLTQFLNRFLFIVG"
     gene            complement(5939..6673)
                     /locus_tag="FD723_RS25175"
                     /old_locus_tag="FD723_25095"
     CDS             complement(5939..6673)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017652386.1"
                     /locus_tag="FD723_RS25175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_25095"
                     /product="FHA domain-containing protein"
                     /protein_id="WP_179069281.1"
                     /transl_table=11
                     /translation="MTDFAQTEIERRLTLYQVFLKLYEHHSSLLDEILQLENVSQPSLT
                     RVKACYVHGVVDTAAVYLMTNLCDNQTQSLRQPQRIWTIGRNRTSGICIADSHLSRRHA
                     AIQHIDEQGFYLIDFNSTNGSFVNGDRAVGPIKLKDGDRIRLGNMTFDFFVNYTYRVLP
                     TVAIDLLMQLVHRKGNHPVEMLTYSQNRQKPLTEKPDLNLETFRNFGLVEKQENPYENF
                     SSEQKSEILDRFFTRQIPSNLR"
     gene            complement(7897..9486)
                     /locus_tag="FD723_RS25180"
                     /old_locus_tag="FD723_25100"
     CDS             complement(7897..9486)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011321579.1"
                     /locus_tag="FD723_RS25180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_25100"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_179067806.1"
                     /sec_met_domain="Pkinase (E-value: 3.5e-35, bitscore:
                     120.2, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYCLSPTCPNPENLVYSQRCQSCGSQLLLRDRYQVIKPLGQGGF
                     GATFLANDQGLPGEPSCVIKQLRPSGSAPHVLQMARELFEREARTLGKIGNHPQVPRLL
                     DYFEDHEQFYLVQEYISGDTLQEEVKINGILSETGVKQFLSEILPLLQYIHEQKVIHRD
                     IKPANLIRRTQDARMVLIDFGAVKNQISQGTTNPSGQTALTAYAIGTPGFAPPEQMAMR
                     PVYASDIYALGVTCIFLLTSKTPKDLDYNPNTGEMIWEHLVQVSDHLSNVLRKMLDVSV
                     RNRYQSAADVLRALEIEPYLDSLAKGLLIKSESGSRDRTHNENSAVLCNNPSATSTGVA
                     QVAAAIRARRAKTAEAGGLHQGSGMAKSTTFASNSNGSQAQNSKVERKLDTQGLLTAYL
                     KGRRDFALHNLSLLNLQGADLSQTNFHSAQLQKTNLQGANLHNSDFGRASLTRANLKDA
                     NLSKAYFNHADLEGADLRGADLSNAYLSNANLRGANLCGANLTSAKISDEQLALAKTNW
                     MTVRPNGKRGLL"
     misc_feature    complement(9680..9696)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 24.16"
                     /tool="antismash"
     gene            complement(10001..10831)
                     /locus_tag="FD723_RS25185"
                     /old_locus_tag="FD723_25105"
     CDS             complement(10001..10831)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015130356.1"
                     /locus_tag="FD723_RS25185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_25105"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_179067807.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.1e-24,
                     bitscore: 84.8, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 2.2e-07, bitscore:
                     29.0, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLRRDALQILKETSRTFYIPISLLPPGLQEAVASAYLCMRAIDE
                     IEDHPELDNATKVKLLRTISLTLQAGVDGFALDAFFAGFSGYENSLEEVTLRIREWSLL
                     APDTIAPRIWDATAAMADRMAYWAERNWKIHTESDLDRYTFGVAGAVGLLLSDLWTWYD
                     GTQTNRTQAIGFGRGLQAVNILRNHNEDLGRGVEFFPDGWSADNMQEYARRNLALAEAY
                     IQDLPTGPALDFCQIPFTLANGTLDALANGKEKLSRSDVFALIEQLISVNMKAS"
     gene            <11415..11624
                     /locus_tag="FD723_RS43035"
                     /pseudo=""
     CDS             <11415..11624
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558172.1"
                     /locus_tag="FD723_RS43035"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="PNCPEKTLKKIFAYKLKYGFGVFMPHFFAFPISRYCLIGSSFDFE
                     TLQMYGFFQKSDMSPKLYSPSPNS"
     misc_feature    11738..11749
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            11742..13496
                     /gene="argS"
                     /locus_tag="FD723_RS25190"
                     /old_locus_tag="FD723_25110"
     CDS             11742..13496
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017311277.1"
                     /locus_tag="FD723_RS25190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_25110"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_179067808.1"
                     /transl_table=11
                     /translation="MNATQEKLKDRVEQAIVAAFGSDLAGVDPILVPASNPKFGDYQAN
                     VALSLSKKLGLQPRAIAGAIVEKLDVSEICEPPEIAGPGFINLKLKTAYLEAQLNAIQA
                     DPRLGVPAAKTPKREIVDFSSPNIAKEMHVGHLRSTIIGDAIARILEFQGHDVLRLNHV
                     GDWGTQFGMLIAYLREVYPDALTTANALDIGDLVSFYRQAKLRFDADEAFQETARQEVV
                     RLQAGAEDTLHAWKLLCEQSRREFQIIYELLDIKLIERGESFYNPLLASVVEDLDKSGL
                     LVENQGAKCVFLEGFTNREGEPLPLIVQKSDGGYNYATTDLASLRYRIQQDEAKRIIYV
                     TDAGQGNHFAQFFQVARKAGWIPDDVELVHIPFGLVLGEDGKKFKTRSGDTVRLRDLLD
                     EAVSRSHTDLKTRLQKEERQETEDFINEVAQVVGISAVKYADLSQNRTSNYIFSYDKML
                     DLKGNTAPYMLYVYARIHGISRKGDINFKELGNNAVLLQHETELTLAKYLLQLDEVISS
                     VEQDLLPNRLCEYLFELSQKFNQFYDRCPILQAEEPQRTSRLVLCDLTARTLKLGLSLL
                     GIQVLERM"
     gene            13618..14181
                     /locus_tag="FD723_RS25195"
                     /old_locus_tag="FD723_25115"
     CDS             13618..14181
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016872361.1"
                     /locus_tag="FD723_RS25195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_25115"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_179067809.1"
                     /transl_table=11
                     /translation="MVRTPSKNITLEEFLKLPETKPASEYIDGQIIQKPMAQGEHSTIQ
                     GELIITVNAVLKPQRVARAYPELRCTFGGRSIIPDVAVFTWERIPRKENGRVANLFSAA
                     PDWTIEILSPDQRQTKVTKNILHCLNYETQMGWLIDPEEQTIFVYIRNQQPVMLDELDA
                     LIPVPDFASELRLTVGDLFGWLLE"
     gene            14219..14689
                     /locus_tag="FD723_RS25200"
                     /old_locus_tag="FD723_25120"
     CDS             14219..14689
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012410411.1"
                     /locus_tag="FD723_RS25200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_25120"
                     /product="cobalamin biosynthesis protein"
                     /protein_id="WP_179067810.1"
                     /transl_table=11
                     /translation="MQQVLWVGIGCKRGTSWQLIDWAIEQVFRENQLFTGAIAGIATID
                     TKASEVGLIELCHLRNLPLKTFSAEILRSVCVPNPATITDHKVGTPSVAEAAAILAASQ
                     LTSLTIFTFTSVEELRVRFLVPKQIFQPQGQAGAVTLAVAQALNTTSITELH"
     gene            complement(14695..15048)
                     /locus_tag="FD723_RS25205"
                     /old_locus_tag="FD723_25125"
     CDS             complement(14695..15048)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015116011.1"
                     /locus_tag="FD723_RS25205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_25125"
                     /product="phage holin family protein"
                     /protein_id="WP_179067811.1"
                     /transl_table=11
                     /translation="MQHFLLTWLGTAVALLITSRIVDGFIVNNFVVALVASVVIGLVNA
                     FVRPILRLLTFPITLLTFGLFTFVINALTLWLASALTPGYGFEIKGFLPALLGSIVLAI
                     VSSVINYFLRVVD"
     gene            complement(15641..16630)
                     /locus_tag="FD723_RS25210"
                     /old_locus_tag="FD723_25130"
     CDS             complement(15641..16630)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016868230.1"
                     /locus_tag="FD723_RS25210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_25130"
                     /product="peptidoglycan-binding protein"
                     /protein_id="WP_179067812.1"
                     /transl_table=11
                     /translation="MQSSLTESILSYLKLLDPTVNRFRMEKRQKGWWPKRSKSLLAIEI
                     LLFSTTPLLIASTAVVSIAAPQKIAQVNPGDSINRPILKIGSQGERVSELQAALKLLGF
                     YSGAVDGTYSENTASAVARFKQAAGLNPDGIVDASTWQRLFPKEPTVASTVPSSQPRFN
                     SATNFPVPTQASNLTNVANPNPPKKAVTQVATRPEPKPTTPKKAVTQVATSPEPRPATP
                     RKATTSSTKKTPNRNTSTTQTQSNTTTKRTPGIQYTSEGLPILRIGLRGSEVVKLQQQL
                     KKLGFLKGDADGDFGVTTETAVKAAQTRYGLEADGVVGGSTWEVLLRR"
     misc_feature    complement(16721..16733)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.5"
                     /tool="antismash"
     gene            complement(16832..20065)
                     /locus_tag="FD723_RS25215"
                     /old_locus_tag="FD723_25135"
     CDS             complement(16832..20065)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015139363.1"
                     /locus_tag="FD723_RS25215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_25135"
                     /product="PAS domain-containing protein"
                     /protein_id="WP_372743821.1"
                     /transl_table=11
                     /translation="MIWMSGCNALYCYFNSNWLKFTGTHLTTSAREGEIGNIWTCSVHP
                     EDRQRCEDIYLRAFATHNSFQRQYRLRGADGEYRWILDTAAPRFSADGSFVGYIGYCID
                     LTGVPIASSQPSESYSSSTKYSRQLRKITDKNRARELSKALEQLQAETTKRQAVEAQLR
                     QKTSEFAAILQVLPDLYFRLDADGSILDYKQGLMQSLYIPPGDYQGKSLRECLPTVVGD
                     RFYQAITQVLETQSEVSFEYTLPLLEGKNKFEARLLPLPARQIIVLVRDTSENKAALIE
                     SDAKFRSIVENANNVIFALTLEGIFSYVSPNWTEIFGHEVVEVEGKSFIPFIHPDDVHI
                     CTDYFQRILTTGEKQKAIEYRIKHKNGSWRWHTSNSSAIRDANGNVLYFVGICYDTTDR
                     KEAEVALAERARLANFRADVDAALTQSDSLQNMMRCCTEALVEHLDAAFARIWTLNKQD
                     NVLELQVSSGMYTHINGPHKYVPVGQFKIGLIAQEGKPHLTNSVQTDPRVGNKEWAKQE
                     DMVAFAGYPLIVEDETVGVIAMFARQTVTESAFTALEFAAQEIAIGIKRKQAEIALRES
                     AQREALLNRLSNQIRASLDLNYIVETAVQEIHNLFEIDRCVFFWYRQDADVPYWEKVYE
                     AKSSFLPCLLNDQEATNAEIKLIAAKTLSGEIIRINDAETVSDSIAQQFLQDFGFTAFM
                     SLPVHTQSGEIGAFSCGYCSGFRPWLNNEVELLQAVTVQLAIAIDQAKLYTQSRITAQT
                     AQDKAQQLEAALLELQQTQAQLIQTEKMSSLGQLVAGIAHEINNPVNFIYGNISHASEY
                     TKDLLHLVELYQQSYCPPTPEINQQIDTIDLDFLRQDLPKILESMKMGAERIRQIVLSL
                     RNFSRLDEDGTKAVDIHQGMDSTLLLLQNRLKAKPGHPGIQVIRDYGNLPPVVCHAGQM
                     NQVFMNLLTNAIDVLEEGVGSEEEPGEPGVGSRGKIPLLCTLSPAPLPLVPHTQCPIPT
                     IRIRTLIQEDYVIISIADNGPGMTEEVRKRLFDPFFTTKAVGKGTGMGLSISYQIIVQK
                     HAGKIDCSSAPGEGAEFVVMIPLKQEPST"
     misc_feature    complement(20208..20222)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.32"
                     /tool="antismash"
     misc_feature    complement(20319..20335)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 25.28"
                     /tool="antismash"
     misc_feature    20394..20408
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.46"
                     /tool="antismash"
ORIGIN
        1 cttgctacga gcagggcgac ggttgcgttc tataacactg agggctgatg ctcaccatct
       61 gtttaccgat gtggtgactt cgggtggtgt agtagttgga atcttactcg tcaagctaac
      121 aggcactctc gtactcgatc caattgtcgc cctgatagta gcagcaaata ttacttggac
      181 aggatttcgt ttgctgcggg aaaccagtag cgcgttactg gatgcagctt tacctaaaaa
      241 agaaattgac gcaattaaga gcatccttaa cgagtacaaa cgtcaagata ttcagtttca
      301 tgccttgcga acccgtactg ctggaacccg ccgttttgtt tcctttcatg ttcttgtgcc
      361 tggatcttgg acagtacaac aagggcatga tttatgcgag gcaattgagc ttgctattct
      421 tggggtgctg ccttcaaccc acgttacaac tcatttagaa cctgtagaag atccagtttc
      481 ttgggatgat ttggagttgg agcgtccgag caatcaccaa atgtaaaaac aagaattaaa
      541 taacatacaa tttatgtctc tggtttacct cacactaggc tgtacctgca tcgttttcta
      601 tctgaacccg ttgcacatca gtgtctttta gtccagcacg ttctagtact tgtactgcaa
      661 aaaagtagct ttttcccgat gggttgccga ttttcttacc ctttaaatca gttaccttct
      721 tgatgggtga gttaagtaaa actagcaatc cgtgggtctt tgggctacgt tcaactaagg
      781 cgatgacagg gatgggctga cctgcggcga tcgcagctac aggtgcattg gtgtcaactg
      841 aagctggaaa tagcttaact gttggcttcc atgcccgccc ggaaataaat aaatgagtaa
      901 tgagtaatga gtattactta ttactcatta cttcaaaaat aaattttcgg aaaagaaaac
      961 tcagcaatca tgagtcagac tattggcgct gctaaaattt cgattattat tccggctatt
     1021 aacgaagcgg gtaatattaa aaaagccatt gctactactc aaggcagtat aaatatagaa
     1081 gtcattgtag ttgatggtgg ctctagtgat gatactgtag cgatcgctca gtctttaaat
     1141 gtcaaagtta tctcatcatc tcccggtcgt gctgtgcaaa tgaacgcggg tgctgtagcg
     1201 gctagcggtg agattctgtt atttctccat gcagataccc gtttaccaac tgggtttgat
     1261 gagatgattc gcacagcact acaacagcct gggactgtgg ctggtgcttt taagttgcgg
     1321 attgatgcgt cacttttaag tttacgatgg gtagagtggg gggtaaatgt gcgatcgcat
     1381 ttttaccaaa tgccttatgg cgaccaagca atttttttaa caaaggaaat atttcagcaa
     1441 ataggctgtt ttcccgaatt gcctatcatg gaagactttg aacttatgcg tcgtttaaaa
     1501 agcatcggac acattgtaat tatcgctaca ccagttgtca cctcagcccg tagatggttg
     1561 caaaagggag tattcaaaac tacgctactt aatcaaatag taattactgc ttatttactc
     1621 ggcatttcac ctgagcgaat tcgtcgctgg tatcgccgag acaaatttaa gagggtttaa
     1681 gaggatgtta ggactagccc agaatccccg aattcagcta tgcacattcg gggaattatg
     1741 tcaatttact tcaccttttt cctgaaggag cgatcgccaa tcttcaatcg ccttctccgt
     1801 ccacaaccaa tttttagcta atttatctac ctggaaattt tctcgatcgg acttgagaac
     1861 catttgccgc aacttcatcg cttcattgag atactgtatc tgcttaccac tagattgact
     1921 aagtgcagat ttatacaatc caagagctaa cccagcataa gaagttaaag cgtcttgagg
     1981 cacttccgtc tttgtggatg ttgagtctgt attctgttct ttgagagcta aattcaaagc
     2041 cttaaaccaa gaatcattgg ctcgatttag attgccttct gtgtagtagg caaatcccaa
     2101 agcgttatta tacaaaagcg attcaggttt agctttggca gcagtttccc agtaacgacg
     2161 ggcatcatca atactataat tattgtctcc ggtttggata gactgccacg ccaatcgtcc
     2221 cttgtaaaaa ttcacagatg ggtcgtcagc ctgtttactg ggaattaatt tcagagcagt
     2281 ttcagccgca gctaatgcgc cccgattgag tagttcttct acagccaata acccaccttg
     2341 caattcaccc tggctcaatt tttccgtagc agtagccgtg acaataccag ttgcttctat
     2401 tcctaaatca atgttcggct gcttttgaat cggtcgagaa tcaggtagag actgggtggg
     2461 aattactggt atattaggca gagttgattg gtttcgattt tgccaccacc aatttaaagc
     2521 gatcgcagcc gctaacgcac tgattcccac aacacccaca atcggccaca gcctgcggcg
     2581 acgggtacga tttcttgctg aaagtggttg cggcaagaaa ttagaatttt gccaatttcc
     2641 ttccaggttc ccaggagttg caggtggtgg cggtggaact tctccccaca aatctgcttc
     2701 ctcttgcaaa gaagtcattt cctcagaaat ctggttttgg tgaagactat tttcacgaat
     2761 ttgtcgatcc ggttcaatta cagctttttg gttatctagt tgacgaaaca aatccgaaac
     2821 gatcgcagaa tcttcttcat aacttgggtc atcatactca atttcatcaa ccaaatcgcc
     2881 ccaagtatct tcacccagcc agtccaaccc agaagagtca cgtgtcaaac cagaaggaat
     2941 catatcttcc attcctaaag gtatctcgct atcatcaccc atagcagagt acatcgtgga
     3001 agttgcccct aaaggcgaac tatactgatt cagcgactcc gtatttgcgg ataactcagt
     3061 ttcctgactc agaaaaccgt caaattctgg ctggagatat aaaatcggta atgcccagta
     3121 catctggtga gaaccataag cagaaattaa tccttggcgc acccgactga cgcacaaatc
     3181 tactggatat ccctgactca agttgcggta aaacaattgt gtaagtgtca acgccacttc
     3241 atcaggaatt cgttctgaca tcgccaaaac gcttctaatt ccccgcttca ccagactttc
     3301 tgctaggtta cgttcgccag tatctccaga gggattggac gcagcggtgt atgcccctaa
     3361 gcaggaatta aacactgcca tttgaatgtt attgttgacg agcaaacctg ccaaatcgtc
     3421 cccagtcaag atttccgtta agccagttct gcgactaaca agataaattt ctccaccatt
     3481 ggaacctaag ttactatgac cagagtagtg tagaacgtgg tatctacctt gttctaaggc
     3541 ttgtgtcagt tcttcccgtc ctggttggtc taatacagtc agttcaattt ctggcaaacg
     3601 attgctacct tcagccagtc gtgatgtttg gcgctgaagt tccgcctgta atttaatcgc
     3661 ttcctgtttc tgtaaatcaa gacggacttg atctgaggga gaagcaatta ccatcaatac
     3721 tttgacacca ccttgttcta gtggtgtggg catattttgc gatcgcaaag gagaagcccc
     3781 cgaaattcca ctttggaatc gagaaaaagc cacataaggc ccagtagcca gagggcgatc
     3841 gcctgcgtgc atcacttccc aaggcaaacg agctaaccta gtgtctttta gccccaaacg
     3901 taagcgtagt acttgttggt ggttctgagc aataccttgg gcagtaatcc aactatctct
     3961 gagagtacct tgaaataagg cattatagaa ttgttgaccc aatgccacca aattaacaga
     4021 gtttctggcg atatcgcttt catgcccgcc agaagtgaat ggatctcctt gtaacaccga
     4081 cttcaacggg tcattcatca aatgcccagc agccatcaac caatcagcta tgggccaagt
     4141 caccaattct tctgccaatg gtaccccagg cgcgacttgt tccgtccgca ccaagtagtc
     4201 attttgccct accggggtta cggaaatatg gaattcctgg gtcacaactt ctcctgcttg
     4261 cctcctaaat ctggtttgaa acgcgaaagt ttcaagtcga tttttcgctc cctctaataa
     4321 cttagatgca tcctgcccct gaatgtttct aattcagtgc cattttgatt tttctgccct
     4381 gacaacttta tccggatcgg attacttggg tctagaacac ttaattggta gatgcacctt
     4441 gatcttcaac tcccctagtt ggctaacacc cactgggggt ttttttattt tggcaaacaa
     4501 cagcaacttc tgacgcagat attctctacc agaaaatagt gcttaatcct agaatacttg
     4561 attagtagat ggatgtccct tgatctttaa ctcccctaat cagttaatat tcactcttgt
     4621 tttttttgac acacgataac aatcaatttt ctaataaatt tatccggagt atggcagtta
     4681 aacctagaac atttaagtgg tagatgcacc ctgataacta gctcccctgg ttggctaacg
     4741 cccactgggg gtttttttat gaagattgag tggtattaat taaccctggc acacccattt
     4801 tgtcaagtag cgcactgata tttaattggt agatatatcc tgataactaa cccctctgag
     4861 gttttttctg accgccaaat agcaaaaact tcaacctctg ctaatttatc cggtagcgac
     4921 caatttactt tagaaaagat tattggtaga tgcaccctga taactaactc ccccgtaggt
     4981 taacaccaac tggggttttt ttatttaaaa aaatagctga ccttgataac taactcaccc
     5041 gattggctaa cacgcacttg aggttctttc tggtttcgta agtgtagccg atcctagaca
     5101 tcaccatcaa tcctaattta gttcattttc tccggaagat actagctgcc cctagaaaag
     5161 attattggta gatgcaccct gataactcac tcccctgtag gttaacacca actggggttt
     5221 ttttatttaa aaaaatagct gaccttgata actaactcac ccgattggct aacacccatt
     5281 tgaggttctt tctggtttcg taagtgtagc cgatcctaga catcaccatc aatcctaatt
     5341 tagttcattt tctccggaag atactagctg cccctagaag agattattgg tagatgcacc
     5401 ctgataactc actcccctgt aggttaacac caactggggt ttttttattt aaaaaaataa
     5461 ctgacctttg tacaatttca tccggagtat ggtgttcaac ctgagaacat ttaattggta
     5521 gatgcaccct gataactaac tcccctggtt ggctaacgct cactgggggt ttttttacgt
     5581 aaacgcgaaa cagttacaga ttgcagtctt ctctacgaga cgctgcactt tggcggaagc
     5641 ctctcgcaga aaaggcagtt tccgtcgtta gatatcgcct tagcatttta ggcccagatg
     5701 accgaagtgc gccactactc ttgttgctac tgctggtaga ccttgagtat cctcctgttg
     5761 tcgggataga ggataacttg ctcactcaat tcctgaatcg ctttcttttt attgtgggct
     5821 aaagatgcta ctccaaaatg attgctatga tatttaatca cattcttaat tttttttcta
     5881 tattttcacc tctttctctg acagcaggat tgctgtcaga gagcatccaa ttatttagct
     5941 acctgagatt agacggtatt tgtctggtaa aaaagcggtc tagaatttct gatttctgtt
     6001 ctgaactgaa gttttcataa ggattttcct gcttctcaac tagtccaaaa tttctgaaag
     6061 tctctaaatt taaatctggt ttttcagtta gaggtttttg tctattctgg gaataagtaa
     6121 gcatttctac tggatgatta cccttccgat gcacaagctg catcaataaa tctatagcta
     6181 cagttggcaa aacgcggtag gtataattta caaaaaaatc aaaagtcata ttgcctaaac
     6241 ggatgcgatc gccatcttta agcttgatcg gcccgacagc gcgatcgcca ttcacaaagg
     6301 agccattagt actgttgaaa tcaattaagt aaaagccttg ctcatcaata tgttgaatag
     6361 cagcgtggcg acgagacaga tgactatcag caatgcaaat accactagtg cgattacgac
     6421 ctatcgtcca gatccgttgt ggctgtcgta aactttgagt ctgattgtcg cacaagttag
     6481 tcatcaaata aacagcagca gtatcgacta cgccatgtac gtaacacgcc ttgactctcg
     6541 tcaacgacgg ttgagataca ttttctagct gaagaatttc atctaaaagg ctgctgtggt
     6601 gttcatataa cttgaggaat acttgatata aagttaatcg ccgttctatt tctgtttgtg
     6661 caaagtcagt cattatacgt aaaccttgta ctacctgatt tcggtcgtga atattctgtt
     6721 tcagcctaca atcagggata attgattttt cgctttccgc tgccatctga aaacttgagt
     6781 ggcttaagag cgttctattt tacaactttt aggtgcgaga ttccctgttg tttctagcca
     6841 taaaaagcat ggaaatatgt ttaaaaaatt attatgatgc tttattgttt attgtaaata
     6901 atcatttgtt atttgtaaca gatagaaatc ataaagattt tattaagaat tgctaattat
     6961 ctacgtattt ctgctataaa gctggatatt tcttaacatt tgcgagagca atgactatcg
     7021 atgaatctaa acattatatc tatttggtca attctgaaaa aatctgagtt tttaccctga
     7081 atcatcagga ctgattttcc aagctagcaa taaaatatca gctttgcgat ccttataaaa
     7141 caagcatttt ataattgtca gtaagtacag tccactacaa aaagagtatg ggatttaatc
     7201 attcgtaagt tggatttcac tactttccac ccaacctaaa ctctcgatat ctccgaacct
     7261 tttttacggt gacgtgtact aagtagaaag gcttaattaa attaaaactg ctaagaagcg
     7321 gctctagctc ttgagaacca ggctatgaat aaaatttgat attacattta attcaataca
     7381 gttcagaatg agctataaaa cacttgtata gacggcgatt tatcgcgtct caaaaaccaa
     7441 aaactgttgc cagaagccct tcatacaagt gtattgacat ttaattacgt ctataataat
     7501 ttgtgcagaa gttataaata aaaagatccc cgacttcctt caataagccg gggatctgaa
     7561 ccttccactg agaggcaatc aaataggatt gatataccta attaatggat cattaaaaaa
     7621 gcagggagac tattttacta atctaaataa tcggtttcaa tcaaaaggat tcatttgtaa
     7681 atatagtcta gaatctaata tccaaaatta attaacaagt aaaaatataa tccccataaa
     7741 tttatttatg ggcttgtggc catttttatt tttctttctt ttgccttttt aatttttact
     7801 tttgctttgt tcagtcaccc aatctaaaaa tcattccact ttgcttaact cttgctaata
     7861 gagcaagcaa gtggctctca agtttaaact ttccaatcat aacaagcctc gttttccatt
     7921 ggggcgcacg gtcatccaat ttgtttttgc tagtgctaac tgctcatcag aaatcttggc
     7981 actggtgaga ttagcaccac acagattagc tcctcggagg ttagcattac tgagataagc
     8041 attgctgagg tctgcgcctc gcaggtctgc cccttctaaa tcagcatggt taaagtatgc
     8101 tttgctcaaa ttagcatcct taagatttgc tcgagtgaga ctggctctgc caaagtcact
     8161 attgtggaga ttagcccctt gaagattggt tttttgcaat tgagcagaat ggaaatttgt
     8221 ttgggataag tcagcacctt gcagattcag caaacttaaa ttgtgtaagg caaaatcccg
     8281 ccttcctttg agataggctg ttaacaaacc ttgggtatct aatttccgct caactttaga
     8341 attttgagct tgtgaaccat tgctgttgct agcgaaagtt gttgatttag ccatcccaga
     8401 accctggtgt aatccccctg cttctgctgt cttggctcgt cttgcacgaa ttgccgccgc
     8461 tacttgtgcc actccagtac ttgtagcaga aggattgtta cataaaacag cagaattttc
     8521 gttatgtgtt cgatctctag atccactttc agatttaatc agtaaacctt tggctaaact
     8581 atctaagtat ggttctattt ccaatgctcg tagaacatct gctgctgact gatagcgatt
     8641 acgtacagat acatctaaca tttttcgcaa tacattgctc aagtgatcgc tcacttgcac
     8701 aagatgctcc caaatcatct cgccagtgtt gggattgtaa tctaaatctt taggagtttt
     8761 gctagtcagt aaaaaaatgc atgtcacccc cagtgcataa atatcactgg cgtagactgg
     8821 acgcatggcc atttgctctg gaggtgcaaa accaggagta ccaatagcat aggcagttaa
     8881 tgctgtctgt cctgatggat ttgtcgtacc ttggctgatt tgatttttga cggcaccaaa
     8941 gtctatcagt accattctgg catcttgagt gcggcgaatt aagttggctg gcttgatatc
     9001 acggtgaatc actttttgct cgtggatgta ttgcaacagt ggcaaaatct cgctcaaaaa
     9061 ttgcttgact cctgtttcac tcaagatgcc gttaattttg acctcctctt gcaaggtatc
     9121 gccactgata tattcttgaa ctaagtaaaa ttgttcatga tcttcaaaat agtctaataa
     9181 tcttggtact tggggatgat tgccaatctt acctagagtt ctagcttctc gctcaaagag
     9241 ttctctggcc atctgtaaaa cgtgtggggc gcttcctgat gggcgtaatt gtttgattac
     9301 gcagctcggt tctcctggta agccttggtc attggctaag aaggttgctc caaagccacc
     9361 ctgacctaat ggtttgatca cctgatagcg atcgcgcaac agaagttgcg agccacaaga
     9421 ctgacacctt tggctatata ccaaattttc tggattggga caggtcggac ttaagcagta
     9481 gctcatgcac tctcaactcg ctgcacgaat aatcacgggg aatgttatac tcccttccaa
     9541 ttatttagat attaatcaac ttctgccagg taatttttgc gggaaatcct ttgaagagtt
     9601 gctaaagttt agctgagatt acgtatagcg atcgctagta ccagatgatt tattatactt
     9661 aaactgataa ataatattta tgctacttta tatcaattcg taatgatgct ctcccaattc
     9721 actaacgtaa tttgcaattg agaaagtttg ctttaattta gtggtctatg tcagtaattt
     9781 tgagcggttc gtagtgggtg gctgtagctc tcacctcagc acttaagtga ataccacgaa
     9841 atcccttaac ctgtcatcat ccctacggta gattattagg tttccctgtg attgcatata
     9901 caggactttg caagtaaatg agttcagaag cctacaccga cctgagtaca ggtacggtgt
     9961 aagtagttca caatcgtctc cattagtcct taagagacta ttagcttgct ttcatgttca
    10021 cactaatcag ctgttcgata agtgcaaaaa catcactgcg gctaagtttc tctttaccat
    10081 tagcaagagc gtcaagagtg ccgttagcta aggtgaaggg aatttggcaa aaatctaagg
    10141 cggggcccgt aggaaggtct tgaatgtaag cttctgccag tgctagattg cgccgggcat
    10201 attcctgcat attgtctgca ctccaaccat ctgggaagaa ttctactcca cgccccaaat
    10261 cttcattatg gttacgcagg atattgactg cttgtaagcc tcgaccaaac ccaatggctt
    10321 gggtacggtt tgtttgtgtt ccatcatacc aagtccataa atctgaaagt aacaatccca
    10381 ctgcacctgc aaccccaaag gtataacgat ctaaatcaga ttcagtgtga attttccagt
    10441 ttctttctgc ccaataagcc atccggtcag ccattgcagc agtggcatcc caaattcgag
    10501 gtgcaatggt gtctggtgct agcagtgacc attctctaat cctcaaagtg acttcttcta
    10561 atgaattctc atacccacta aatcctgcaa agaaagcatc tagtgcaaag ccatcaactc
    10621 ctgcctgtaa tgtcagacta atcgttctta acagcttgac tttagtagcg ttatctaatt
    10681 cgggatgatc ttcaatttca tcaatggcac gcatacacaa atatgctgat gcgactgctt
    10741 cttgcaatcc tggcggtaaa agactaattg ggatataaaa agttcggcta gtttctttga
    10801 ggatttgcaa tgcatctcta cgtaaattca tgttttcact ccccgcttga tttttgcacc
    10861 acatgaagtt tgcagttttt tgatgatact ggatatagtt ttgactaaac cttaaaaact
    10921 atagactata agataggcta gtatttcatc taaaaattga tggtttttgg tgttgcaatt
    10981 aacaaaactc tcaaattgat caaagtctag tctagtatag aggtttttgg ttgcaaaagt
    11041 gtttgaggtg tcgtttgata tcgctttcat aaacttttag tatagatata aagaattatg
    11101 gtaatatttg gttgaatatt gcgaaaactt tccatgagca aacatccatt ttagggattt
    11161 gaaagtgttt ttagtctgcg ttaatctgac taaaaaatgt aattattgta tatataaaga
    11221 caattcagga aaagtcggta acggataaca gcatctatac ggacttttag atgcatatag
    11281 cggtttgccg aaaagttagg gtaagttaaa ttggacaccg agggctgcgg ttagctaggt
    11341 ctatgctaat taaagagtga catcaaatga ccataaccca gaaccagaag ttcctgtata
    11401 catactagat tgttcctaat tgcccagaaa aaaccctgaa gaagatattt gcttacaagc
    11461 taaaatatgg gtttggcgtt tttatgcctc atttctttgc ttttcccatt agccgttact
    11521 gtttgattgg ttctagcttt gatttcgaga ctcttcagat gtacggattt tttcaaaaat
    11581 cagatatgag tcctaagctt tattccccat ctccaaatag ctgatgacta atgacaaccc
    11641 tcgaagatca atcaggggtt gttaaaatcc ctcaatactt tagagtgaaa taatcaagct
    11701 tttctagagc tacattcccc tctcacagat aaaatttata tatgaacgct acacaagaaa
    11761 aactcaaaga tcgggttgag caggcaatag ttgcggcttt tggctctgac ttagctggag
    11821 tagatccaat tttggttcct gctagcaatc ctaaatttgg tgattatcag gcgaatgtgg
    11881 ctttatccct gagtaaaaag ttaggattgc aaccaagagc gatcgcaggt gcaattgttg
    11941 agaaactaga tgtatccgaa atctgtgaac caccggaaat cgctgggcca ggatttatca
    12001 atctgaaact gaaaacagca tacttagaag cacaactaaa cgcaattcaa gctgatccca
    12061 gactgggagt tccagccgca aaaacgccga agcgggaaat tgtagatttt tccagtccga
    12121 atattgctaa agaaatgcat gtcggacact tgcgttctac aattatcggt gatgcgatcg
    12181 cccgaatttt agaatttcaa ggacacgatg tactgcggtt aaatcatgta ggtgattggg
    12241 gtacgcagtt tggcatgtta atcgcctatc tacgggaagt ttacccagat gcccttacaa
    12301 ccgctaatgc tttagatatt ggtgatttag tctcttttta ccgccaagcc aaattgcggt
    12361 ttgatgcaga tgaagctttt caagagactg cacgtcaaga agttgtcagg ttacaagcag
    12421 gtgcagaaga tacactccat gcttggaaac tgctgtgcga acagtcgcgg cgagagtttc
    12481 aaataattta tgagttgctg gatatcaaat taattgaacg cggggaatct ttctataacc
    12541 ctttactagc tagcgttgtg gaagatttag ataaatctgg gttactggta gaaaaccaag
    12601 gggcaaaatg cgtttttctg gaagggttta ccaatagaga aggtgaacct ttgccgttaa
    12661 ttgtgcagaa atcagatggc ggttataact atgccacaac tgatttagca tccctgcgct
    12721 accgaattca gcaagatgaa gcaaagcgga taatttatgt aaccgatgct ggacaaggaa
    12781 accattttgc ccaattcttt caggtagcac gcaaagctgg atggattccc gatgatgtgg
    12841 aattagtgca tattcccttt gggctggtgt taggagaaga tggtaaaaaa ttcaaaactc
    12901 gttctgggga tactgtgcgg ttacgggatt tgttagatga agctgtttct cgttcacata
    12961 ctgacttaaa aactagatta caaaaagaag aacgccaaga aactgaagac tttattaatg
    13021 aagttgctca ggtagttgga atcagtgcag ttaagtatgc agacttaagc caaaatcgca
    13081 ccagtaatta catcttcagc tacgacaaaa tgctggatct caaaggtaat actgcgccct
    13141 atatgctgta tgtttatgcg cggattcatg ggattagccg caaaggtgat attaacttta
    13201 aagagttggg aaataatgcc gttttgttac agcatgaaac agaattaacg ctagcaaaat
    13261 acttacttca actagatgaa gttattagta gtgtagagca agacttgctg cctaatcgtt
    13321 tatgtgagta tttgtttgaa ctgagtcaga agtttaacca attctatgat cgttgtccca
    13381 tattacaagc cgaggagcca cagaggacat cccgcttggt tttatgtgat ttgactgcta
    13441 gaactctgaa gttgggatta tctctgttgg gaattcaggt attggagagg atgtaatatt
    13501 tttcaacgca gagttacgct gaggtagcgc aaaggtacgc agagtaagag ttaagttaaa
    13561 gcttctttgt ttcctttgcg gtttttttaa ttataattgc aggatttgga ggcgattatg
    13621 gtacggacac catctaaaaa tataactttg gaggagtttc tgaagttacc ggaaactaag
    13681 cctgctagtg aatatattga tggtcaaatt attcaaaaac caatggcaca gggagaacat
    13741 agcactattc aaggtgaact gattattact gttaatgctg tcttgaaacc ccaaagagtt
    13801 gcacgagcat atcctgaact gcggtgtact tttggtggca gatcaattat cccggatgta
    13861 gcggtattta cctgggagag aatacctcgc aaagaaaatg gcagggtagc aaatttattt
    13921 tcagccgctc ctgattggac tattgagatt ctatcgcctg accaaagaca aacgaaagtt
    13981 acaaaaaata ttttacattg cctgaattat gagacacaaa tgggttggct gatcgatcca
    14041 gaagaacaaa caatatttgt atatattcgc aatcaacagc cagttatgtt agatgaacta
    14101 gatgctttaa ttcctgtacc agattttgca agtgagttga ggctgacggt gggagattta
    14161 tttggttggc tgttggagta aaccaaattc tgaccaattg aataaggaaa taggccaagt
    14221 gcaacaggtt ttatgggtag gaatcggttg taaacgggga acatcatggc agttgattga
    14281 ttgggcaatt gagcaagtgt ttcgagaaaa tcaacttttt acaggtgcga tcgcaggtat
    14341 tgctaccatt gacactaaag cctcagaagt tggcttaata gaactttgcc acctccgtaa
    14401 cttgcctcta aagacctttt ctgccgaaat ccttcgctct gtgtgtgtcc ccaatcctgc
    14461 cacaattact gaccacaaag taggtacacc tagcgtagca gaggcagctg ctattcttgc
    14521 agcttctcaa ctcacatcgt tgactatttt tacctttaca agtgtggaag agttgcgagt
    14581 caggttctta gttcccaaac aaattttcca accacaaggg caagcaggag cggtaacttt
    14641 agctgttgcc caagctttaa atactactag tattacagaa cttcactaat ttttctagtc
    14701 aacaactctc aaaaaatagt taattacgct agaaacaatt gctagcacaa ttgaacctaa
    14761 caaagcaggt aaaaagcctt taatttcaaa accataacca ggagttaggg cacttgccag
    14821 ccaaagggtt aaagcgttga tcacaaatgt aaataaacca aaggtgagta aggtaattgg
    14881 aaacgtcaaa agacgcaaaa taggcctgac aaacgcatta acaagaccaa taactacaga
    14941 tgcaacaagg gcgacaacaa aattattgac aataaaacca tcaacaattc tagaagtaat
    15001 caataacgcc accgcagtac cgagccaagt taataaaaag tgttgcataa gtttttttag
    15061 agtaattagc agtaagttta attaatttca ctattgccat ctgtgatctg taacacgatt
    15121 aggtatcttg tgcttgactc ctaaagttgc catcatcttt tatcagtcta aaagcaatat
    15181 gagaaggagt cagaattcag aatgggctac gccccgctgc gctaacagaa ttcagaatac
    15241 tctactctgt caagtcaggg ctttcgctaa gaaagaattt aagatcgcgc gcgtttaaaa
    15301 tcgcttgctc taaacctcga ttctccatcc agtcgcacat aatccattct ggattctggc
    15361 tcctgaattc tgaattcttc ttcggtaatt tttcagtgct ggcatagaga tacttctaat
    15421 cggtatatct ttatcgtatt gcaggatgta ccgcattaaa ttcataaaaa atgttgggaa
    15481 gcgcaaaacc cttacaaagg tttctctaat ccgagaaatc tcagtaattg gggatttaca
    15541 agaaataaat tatccagttt tgtacactta gtgtattatc cgcccttagc cagaggtgcg
    15601 ggtaagacgc taagtgtaag tttgaagagt agggataggg ttaacgccgc aaaagaacct
    15661 cccaggtaga gccaccaact acaccgtcag cttctaatcc atagcgcgtt tgtgcagctt
    15721 tcacagctgt ctccgttgtc acgccaaagt ctccatcggc atcgcctttc aagaaaccaa
    15781 gctttttcag ttgttgttgc aacttcacaa cttcagaacc acgtaatcct atacgcaaaa
    15841 ttggcaatcc ttctgaggtg tattgaatac caggggttcg cttcgtagtt gtgtttgact
    15901 gagtttgagt ggttgatgta ttacgatttg gcgttttctt tgtgctggaa gttgtagctt
    15961 ttcttggggt agcaggtctt ggctcagggc tggttgcaac ttgtgttaca gctttttttg
    16021 gggtagtagg tttgggttca gggcgagttg caacttgtgt tacagctttt tttggggggt
    16081 tgggatttgc aacgttggtg aggttgctag cctgggttgg aacaggaaaa tttgtagctg
    16141 agttaaatct tggctgggat gaggggacgg ttgatgctac tgtcggttct tttggaaaaa
    16201 gtcgttgcca agtgctggca tcaacaatac catctggatt caaaccggcg gcttgtttaa
    16261 atcgggcaac agcactagct gtattctcac tatatgtacc gtctacggca ccagagtaaa
    16321 aacccaaaag tttcagagct gcctgaagtt cagatacgcg ttcgccttgg ctaccaattt
    16381 tgagaatagg gcggttaatg ctatctccag gatttacttg agcaattttt tgtggtgctg
    16441 ctattgatac tacagccgtt gaggcaatca acagaggcgt agtagagaac aagagtattt
    16501 caatggccaa taaagattta gacctctttg gccaccaacc cttttgccgt ttttccattc
    16561 taaagcgatt tacagttggg tctagtaatt ttaagtaact caaaatactt tctgtcaggc
    16621 tgctttgcat ggaatttact cccagaatat tctcatgcta atggtacagc cgcttggtct
    16681 aaaaaacagc tgatcattta taatgtctaa gctgttgcgc ctgcaaattg catcacaagc
    16741 atgattaggc aaaacctgta aatcctctcc cttgctccca gcaagaactg ctcccctgcc
    16801 gcctcaatgt gcaaactata atcacaacag cttacgttga gggttcttgc tttagtggaa
    16861 tcatcacaac aaactcggca ccttctcctg gtgctgaact acaatcgatc tttcctgcgt
    16921 gtttttggac gattatttgg tagctaattg atagtcccat acctgtgcct ttacctacag
    16981 cttttgtcgt gaagaagggg tcaaataggc gtttgcgtac ttcctcagtc atgcctgggc
    17041 cattgtcggc aatgctaatg attacatagt cttcttggat gagagtgcga atgcgaattg
    17101 ttgggatggg gcattgggta tggggcacaa gaggcagagg ggcaggggaa agggtgcaga
    17161 ggagaggaat tttccccctg ctcccgactc ccggctcccc tggttcttcc tcactcccaa
    17221 ccccttcttc caaaacatcg atcgcatttg tcaacagatt cataaacacc tgattcatct
    17281 gtccagcgtg acacactact ggtggtaggt tgccgtagtc tcggattact tggattccgg
    17341 gatgtcctgg tttagctttt aggcgatttt gcaacaacag caaggtgcta tccatacctt
    17401 gatgaatatc tactgctttt gtaccgtctt catcaagacg agaaaaattg cgtaaagata
    17461 ggacaatctg ccgaatgcgt tcggctccca ttttcataga ctccaggatt ttgggtaaat
    17521 cttgccggag aaagtctaaa tcaatggtgt cgatttgttg gttaatctct ggtgttggtg
    17581 ggcagtaact ctgttgataa agttctacta agtgcagcaa atccttggta tattcactag
    17641 catggctaat attgccgtag atgaaattga cgggattatt aatttcgtgg gcaatacctg
    17701 caaccaattg tcctaaactg gacatttttt cagtttgaat cagttgcgct tgagtctgtt
    17761 gaagttctag cagtgctgct tctagttgct gggctttatc ttgggcagtt tgggcagtga
    17821 tgcgactttg ggtataaagt tttgcttggt caatggcgat cgctagttga actgtaactg
    17881 cttgtagtaa ttctacttcg ttgttcagcc aagggcgaaa gccactacaa taaccacagc
    17941 taaatgcacc aatttcgcca gattgggtat gtacaggcag cgacataaac gcagtgaaac
    18001 caaaatcctg caaaaactgc tgtgctatgg aatcgctcac agtctcagca tcattaatac
    18061 ggatgatttc tccgctcaag gttttagctg cgattagctt gatttcggca ttagttgctt
    18121 cttggtcgtt aagaaggcag ggtaaaaagg aacttttcgc ctcatatact ttttcccagt
    18181 agggtacatc agcatcttgc cgataccaaa agaagacgca gcgatcgatc tcgaataagt
    18241 tgtgaatttc ttgcactgcg gtttccacaa tgtaattgag atccaaagaa gctcgaatct
    18301 gattagaaag acgattaagt agtgcttctc gctgggcgct ttctctgagt gcaatttctg
    18361 cttgtttgcg cttgatgcca atggcaattt cctgggcggc aaattccaag gctgtgaaag
    18421 ctgattctgt cactgtttgg cgggcaaaca tggcgatcac ccctacagtt tcatcttcaa
    18481 caattaaggg atagccagca aaggcgacca tatcctcttg ctttgcccat tctttgttac
    18541 cgacgcgggg atctgtctgc acagagttag ttaagtgagg tttgccttct tgggcaatca
    18601 aaccaatttt gaattgaccg actggcacat atttatgggg cccattgatg tgggtgtaca
    18661 tccccgaact gacttgcaac tccaatacat tatcttgttt gttcagcgtc cagatgcgag
    18721 caaaggctgc atcaagatgt tcaactaagg cttcagtgca gcagcgcatc atgttttgta
    18781 agctgtcact ctgagtcaat gccgcatcta catcggcacg aaaatttgct aaccgcgctc
    18841 gttctgctaa agctacttct gcttctttgc ggtcagtggt atcgtagcaa ataccaacga
    18901 agtacaaaac attgccattg gcgtctctaa tcgcagatga gttgcttgta tgccatcgcc
    18961 aactaccatt tttgtgtttg attcgatatt caattgcttt ttgtttctcg cctgttgtca
    19021 aaattctttg gaaataatcg gtacagatat gcacatcatc aggatgtatg aagggaataa
    19081 aggatttgcc ttcaacctct acaacctcat gcccaaaaat ttcagtccag ttaggagaaa
    19141 cgtaggaaaa tattccttca agtgtcagtg caaaaataac gttgttggcg ttttctacaa
    19201 tgctgcggaa cttggcatca ctttcgatca atgctgcttt attctcgcta gtgtcgcgga
    19261 caagaacgat aatttgtcgg gctggtaatg gtaataacct agcttcaaat ttatttttcc
    19321 cttctagtag cggtaaggta tattcaaaac tgacttcaga ttgagtttcc agtacttgag
    19381 ttattgcttg gtagaagcga tcgcctacaa cagttggtaa gcattctcgc aaactcttgc
    19441 cctgataatc tcctggtgga atatatagac tctgcatcaa tccttgcttg taatccaaaa
    19501 tacttccatc agcatcaagc cgaaagtaca aatcaggaag cacttgcaaa atcgctgcaa
    19561 attctgatgt tttttggcgc aactgtgctt caactgcttg gcgttttgta gtttcagctt
    19621 gtagttgctc taatgctttt gataactctc ttgctcggtt tttatctgta attttacgta
    19681 attgacgaga atattttgtc gatgatgagt agctttctga aggttggctg ctcgctatcg
    19741 gcactcctgt tagatcgata caataaccga tgtaaccaac aaagctacca tctgctgaaa
    19801 accgtggcgc agctgtatct aaaatccagc gatattcgcc atcagcacca cgcaggcgat
    19861 attgcctctg gaaggaatta tgtgtcgcaa atgctctcag gtatatatct tcacatcgct
    19921 gtctatcttc tggatgaaca ctgcaagtcc aaatattgcc tatctcccct tctcgcgcag
    19981 atgttgtgag atgtgttcct gtaaatttca gccaattgga attgaagtaa cagtaaagtg
    20041 cattgcatcc agacatccaa atcatcagag gagtagtatc ggcttgctga caaaataatt
    20101 tttcattctc ttgtctttct tcctcttcaa caatgatttg gttaacgtag ctctgcacct
    20161 ttttagaaaa cacttttgcc tgcctgctct gcctaaatta ttaaggtaat agtctgaaaa
    20221 tatgatttgt taatacatgg atataatctt tttcatgccg acatgctaac gatcttaata
    20281 ctttattcat ttttatatat gcgcgaattc cgcttttact gtaaataaat tgcaaaaatg
    20341 ctgaagttat gattaagatt aacttcagca ttttttatga aatttaaact atctatattc
    20401 agagaatttg tttgacttta tttctgattt aaataactga aaaattcatc tgagctatgt
    20461 aattgcatta ctcaaaaaca tgatttagct ttacagagac tatatgattt tctgtggagt
    20521 atttacatct ttatcagaaa tttacaataa tgaagaattt tatccaaaat aaatattgat
    20581 ttttcatcaa gaagaattca gtatgaatta gaatctggct gatggatcta gcttccataa
    20641 aatcaggggt ataaaagagg ttgagaacca catctctact aagcaatatc tagtaaattg
    20701 gtggtataaa acccaacttt atttattcgc aatcctggat gatggcgaat gtattctttt
    20761 ttattgttct caacaaaatc caatttttca aaattgtctt gactattgaa aattccttat
    20821 atagcaatcc t
//
