LOCUS       NZ_CP040272            21917 bp    DNA     circular CON 31-AUG-2024
DEFINITION  Nostoc sp. C052 chromosome, complete genome.
ACCESSION   NZ_CP040272
VERSION     NZ_CP040272.1
KEYWORDS    RefSeq.
SOURCE      Nostoc sp. C052
  ORGANISM  Nostoc sp. C052
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
            Nostoc.
REFERENCE   1  (bases 1 to 7828336)
  AUTHORS   Li,F.-W.
  TITLE     Complete genomes of symbiotic cyanobacteria from bryophytes provide
            new insights into the evolution of Vanadium-type nitrogenase
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7828336)
  AUTHORS   Li,F.-W.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2019) Boyce Thompson Institute, Boyce Thompson
            Institute, 533 Tower Rd, Ithaca, NY 14853, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.4.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 84.0x
            Sequencing Technology             :: Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013393905.1-RS_2024_08_31
            Annotation Date                   :: 08/31/2024 08:18:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,527
            CDSs (total)                      :: 8,409
            Genes (coding)                    :: 8,174
            CDSs (with protein)               :: 8,174
            Genes (RNA)                       :: 118
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 104
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 235
            CDSs (without protein)            :: 235
            Pseudo Genes (ambiguous residues) :: 0 of 235
            Pseudo Genes (frameshifted)       :: 84 of 235
            Pseudo Genes (incomplete)         :: 168 of 235
            Pseudo Genes (internal stop)      :: 38 of 235
            Pseudo Genes (multiple problems)  :: 50 of 235
            CRISPR Arrays                     :: 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:15:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5432851
            Orig. end                         :: 5454768
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040272.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Fay-Wei Li, Boyce Thompson
            Institute, 533 Tower Rd., Ithaca, NY 14853, USA.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21917
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="18"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21917
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21917
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11917](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11917
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(875..888)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.61"
                     /tool="antismash"
     gene            complement(993..1760)
                     /locus_tag="FD723_RS22425"
                     /old_locus_tag="FD723_22335"
     CDS             complement(993..1760)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012412479.1"
                     /locus_tag="FD723_RS22425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22335"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_179067333.1"
                     /transl_table=11
                     /translation="MKIDFGATATDYAKHRAGFPSSLFNRLSEYGIGLPGQNIVDLGTG
                     TGTLARGFADRGAYVIGIDPSVSLLEQARQLSESAQLQVDYRVATAENTELPDASADVV
                     TAGQCWHWFDRPRAVQEITRILRRNGSIAIAHFDWIPLKGNVVEATERLIEAHNPAWNM
                     GGGNGLHPLWLQDIGEGGFREIRTFSYDVFVPYTHEAWRGRIRASAGVGASLTQELVEV
                     FDQELATLLETRYPTEILEVHHRVWAAIAKSPL"
     gene            complement(1795..2484)
                     /locus_tag="FD723_RS22430"
                     /old_locus_tag="FD723_22340"
     CDS             complement(1795..2484)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012412478.1"
                     /locus_tag="FD723_RS22430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22340"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_179067334.1"
                     /transl_table=11
                     /translation="MATTALIVGAGNGLSASLARLFAKEGFTVALAARQIEKLTQLSSE
                     IGAVSFAADASKPDEVEQLFIDIENKVGSPNVVIYNPSFRVRGPLVDLDPGEVAKTLDI
                     TAYGGFLVAQAATKRFLQLGGGAIFFTGASASVKGYPLSAPFAMGKFALRGLAQSIARE
                     LAPKNIHVAHFVIDGGIRSAVRQDPVDNPDSTLDPDAIAQTYLSILRQPRSAWTWEVEL
                     RPWVENF"
     gene            complement(2488..3783)
                     /locus_tag="FD723_RS22435"
                     /old_locus_tag="FD723_22345"
     CDS             complement(2488..3783)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1137: Major
                     facilitator superfamily MFS 1"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012412477.1"
                     /locus_tag="FD723_RS22435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22345"
                     /product="MFS transporter"
                     /protein_id="WP_179067335.1"
                     /transl_table=11
                     /translation="MSLPSFLARRSFHYGWIVAGLTFLALLVAAGIRSAPGVFIVPLEQ
                     EFGWSRATISLAISINLVLYGLIGPFAATVMERIGIRRMMVFSLAIIALGVGLTTLMSA
                     SWQLVLLWGVVVGSGSGVIALVLGAIVVNRWFLSKRGLVLGILTASTATGQLVFLPMLA
                     SVADRFGWRIAALALTGAALLIIPAIAAFMRDRPADVGLRPFGDTSETVEVLQPKVNSI
                     ASTLNALWLGMRNRDFWLLFGSFFICGASTNGLIGTHLIPACIDHGIPEVKAAGLLAIM
                     GLFDFFGTTMSGWLSDRWNNRYLLCWYYGLRGLSLIFLPFSFNFSFYGLSIFAVFYGLD
                     WIATVPPTVRLVANVFGKENVGVMFGWIVAGHQLGAATAAFGAGVLRTWTGSYLQAFIL
                     SGVLCLIAAVCVLQIGQSPTKGNSQLSSVMDN"
     gene            complement(4160..4825)
                     /locus_tag="FD723_RS22440"
                     /old_locus_tag="FD723_22355"
     CDS             complement(4160..4825)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159: dihydropteridine reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012412476.1"
                     /locus_tag="FD723_RS22440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22355"
                     /product="nitroreductase family protein"
                     /protein_id="WP_179067336.1"
                     /sec_met_domain="PF00881 (E-value: 1.6e-31, bitscore:
                     108.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTVIQTQPLDVPSAIAKRRSIKTFKTDPIAPELLKQLVELTVAA
                     PSSYNIQSWQIILVQDEAQKAALSAASWNQQQIVQAPVTFVFAADATASETNLNPIIEQ
                     ALATGAWNEGTANYFKTAIPQFQQGLGDKQREYAIKDAIIAATHLVLAAESLGLSTCFM
                     NGWIEDQVKQVIGAGDNPDLAIAVLVPVGYAAEPRLNPGRLPFSSNVSVDRIGNPYAG"
     gene            complement(5085..6197)
                     /locus_tag="FD723_RS22445"
                     /old_locus_tag="FD723_22360"
     CDS             complement(5085..6197)
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015130166.1"
                     /locus_tag="FD723_RS22445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22360"
                     /product="alkene reductase"
                     /protein_id="WP_179067337.1"
                     /transl_table=11
                     /translation="MTADINLFSPYQLGNLELPNRIVMAPLTRNRAAKGNVPYELNATY
                     YAQRASAGLIISEATQVTPEGQGYPATPGIHSPEQVEGWKLVTDAVHQHGGRIFLQLWH
                     VGRISHPDLQPNGVLPVAPSAIAPKGEASTYEGPKPFVTPRALETSEIPQIVEQYRQGA
                     ANALAAGFDGVEIHSANGYLIDQFLRDGTNQRTDKYGGDIENRARFLLEVTEAVTSVWD
                     SNRVGVRFSPSGTFNDIHDSNPLETFGYAAQALNKFNLAYLHIYEATEADIRHGGIIVP
                     TSHIRDRFTGTLIVNGGYTREKGDAVLANKAADLVAFGTLFISNPDLPRRLALNAPLNQ
                     PNQASFYGGGEQGYTDYPFWSTANEPVANV"
     gene            complement(6326..7120)
                     /locus_tag="FD723_RS22450"
                     /old_locus_tag="FD723_22365"
     CDS             complement(6326..7120)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (9-127). E-value: 5.4e-07. Score:
                     21.6. Matches aSDomain:
                     nrpspksdomains_FD723_RS22450_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012412474.1"
                     /locus_tag="FD723_RS22450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22365"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_179067338.1"
                     /transl_table=11
                     /translation="MDLKLHGKSALVSGSTAGIGLAIALGLAQEGASVIINGRSEARVA
                     QAIAKIKHFTPDAKVSGVVADTGTASGVEQLFEKVPHVDILINNLGIYEPKTFFDITDQ
                     DWLNIFEVNVLSGVRLSRQYLQKQLEQNWGRIIFISSESAIQIPVEMIHYGTTKTAQLA
                     IARGLAEMTVGTGVTVNSVLPGPTRSEGVEEFISQLAQERGISPTEVEAEFFQNVRPTS
                     LIKRFATNEEVAAIVVYLSSPVASATNGAALRVDGGVIRSIV"
     aSDomain        complement(6740..7093)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FD723_RS22450_PKS_KR.1"
                     /evalue="5.40E-07"
                     /label="FD723_RS22450_PKS_KR.1"
                     /locus_tag="FD723_RS22450"
                     /protein_end="127"
                     /protein_start="9"
                     /score="21.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="ALVSGSTAGIGLAIALGLAQEGASVIINGRSEARVAQAIAKIKHF
                     TPDAKVSGVVADTGTASGVEQLFEKVPHVDILINNLGIYEPKTFFDITDQDWLNIFEVN
                     VLSGVRLSRQYLQK"
     CDS_motif       complement(7001..7090)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FD723_RS22450_0001"
                     /evalue="1.20E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="FD723_RS22450"
                     /protein_end="40"
                     /protein_start="10"
                     /score="11.6"
                     /tool="antismash"
                     /translation="LVSGSTAGIGLAIALGLAQEGASVIINGRS"
     gene            complement(7268..7591)
                     /gene="trxA"
                     /locus_tag="FD723_RS22455"
                     /old_locus_tag="FD723_22370"
     CDS             complement(7268..7591)
                     /GO_function="GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="trxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017314800.1"
                     /locus_tag="FD723_RS22455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22370"
                     /product="thioredoxin"
                     /protein_id="WP_012412473.1"
                     /transl_table=11
                     /translation="MSSITNVTEATFKQEVLESEIPVLVDFWAPWCGPCRMVGPVVDEV
                     AAEYEGQVKFVKLNTDQNPTVASHYGIRSIPTLMVFKGGRQVDTVVGAVPKTTLNKTLA
                     QHL"
     gene            7672..8022
                     /locus_tag="FD723_RS22460"
                     /old_locus_tag="FD723_22375"
     CDS             7672..8022
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012412472.1"
                     /locus_tag="FD723_RS22460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22375"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_179067339.1"
                     /transl_table=11
                     /translation="MRFLYHPDRKNISLPGVLYALGDPVRLEIVRLLATEGEQCCARFD
                     FAIAKSTMSNHFKILRESGIVLTRKEGTHHINILRREDLEMLFPGLLDAVLKAAQPLPV
                     SPVSTKQIASRI"
     gene            complement(8275..8430)
                     /locus_tag="FD723_RS44190"
     CDS             complement(8275..8430)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020419.5"
                     /locus_tag="FD723_RS44190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_372743819.1"
                     /transl_table=11
                     /translation="MLSNSDRYADDSVEARDLIDLAVLRLRSPIPQVSIEKAERAYQVM
                     RPLKRA"
     misc_feature    complement(8504..8518)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.53"
                     /tool="antismash"
     gene            complement(8574..9839)
                     /locus_tag="FD723_RS22465"
                     /old_locus_tag="FD723_22385"
     CDS             complement(8574..9839)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012412470.1"
                     /locus_tag="FD723_RS22465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22385"
                     /product="glycosyltransferase"
                     /protein_id="WP_179067340.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.6e-19,
                     bitscore: 69.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVIVLGLMLLSLTIWLGLLCFWGQFWRTDQQLEVETLYTTSLKS
                     LPVVCAVVPARNEAELIPTSLRSLLLQDYPGSFTVFLVDDRSTDRTANFAEGVAHAVGK
                     PQQLHIISGESLPPGWSGKLWAVEQGIKSANKLAPDYFLLTDADIEHDPGNLRRLVAKA
                     VQEDLDLVSVMVRLRCESFWEKLLIPAFVFFFQKLYPFRWVNNPNNPTAAAAGGSILIA
                     REALERIGGIQVIRQALIDDCALAQAVKKSRGAGEQGSRGDKENNHTYNAQYLIPSQGR
                     IWLGLSSLTRSLRPYDSLATIWDMVARTAYTQLNYSPLLLLGTLVGMPLIYLAPPVCMI
                     LGAVWGNWAIAFTGLFGWLLMTVAYYPTIRFYKCSPWFALSLPAIAFLYTLMTLDSALR
                     HWQGRGGAWKGRVYPSSDNTSF"
     gene            10001..11917
                     /gene="shc"
                     /locus_tag="FD723_RS22470"
                     /old_locus_tag="FD723_22390"
     CDS             10001..11917
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015126635.1"
                     /locus_tag="FD723_RS22470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22390"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_179067341.1"
                     /sec_met_domain="T2TS (E-value: 8.2e-132, bitscore: 439.0,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTQDRVKVNQVAEAIAASQEYLLSIQNPAGYWWAELESNVTITA
                     EVVLLHKIWGTDQTRALHKVEAYLRQEQRQHGGWELYYGDGGELSTSVEAYMALRLLGV
                     PVSDPAMLRAKTFILQRGGISKTRIFTKLHLALIGCYNWRGIPSLPAWVMLLPKAFPVN
                     IYEMSSWARSSTVPLLIVCDRKPVFLTDSAINLDELYAEGVDRVQWELPQSGDWTDLFL
                     TLDRGFKLAESLNLVPFRQEGIKAAEKWILERQEATGDWGGIIPAMLNSMLALRCLDYD
                     RNDPIVERGLQAIDNFAIETDNSYRVQPCVSPVWDTAWVMRALVESGFAPNHPAVVKAG
                     EWLLQKQILDYGDWAVKNRQGKPGAWAFEFENRFYPDVDDSAVVVMALHLAKLPNEKIK
                     QAAIARALNWIASMQCKPGGWAAFDLDNDQDWLNSIPYGDLKAMIDPNTADVTARVLEM
                     LGACDLSIDSDNLERSLTYLLHEQETEGCWFGRWGVNYIYGTSGVLSALALIDPQRHKL
                     SIERGASWLVGCQNPDGGWGETCRSYNDPSLKGKGNSTASQTAWAIIGLIAAGEATGKL
                     ALEVIERGISYLVTTQKPDGTWFEADFTGTGFPCHFYLKYHLYQQYFPLIALGRYQAVI
                     QKG"
     misc_feature    12046..12061
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.77"
                     /tool="antismash"
     misc_feature    12150..12168
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 29.39"
                     /tool="antismash"
     gene            12302..13285
                     /locus_tag="FD723_RS22475"
                     /old_locus_tag="FD723_22395"
     CDS             12302..13285
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012410616.1"
                     /locus_tag="FD723_RS22475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22395"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_179067342.1"
                     /transl_table=11
                     /translation="MFKLLRYLSIFLITACLLFACNSSAPTKLKRPPLKIPSAYFVGEY
                     PSIIAQEKGFFKAQGVDVELIHKRYIQLVQGNLSAGKYDGAISSLGGFIILSATNPDIQ
                     GVMVVNESTGADVVVAQSPIKTVADLKGKKLGANLGGFSEVFVTEMLKTANLSSDDVNL
                     VKLEASEIPQRLKNNDIQAGHTWEPYLSEAKKKLGGHILFTSKQTPGLISDMMVFRGET
                     IRDRPEDIRAFIRGWLQATTYWKANVQEGNAIISKALKIPINTISLEGVNLTDLDENKK
                     LFQSSNPHSIYKTAKIYADFFIRSGNVTRIPELKSLFNPSFLNSSS"
     misc_feature    13420..13438
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 25.18"
                     /tool="antismash"
     gene            13450..16104
                     /locus_tag="FD723_RS22480"
                     /old_locus_tag="FD723_22400"
     CDS             13450..16104
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016953095.1"
                     /locus_tag="FD723_RS22480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22400"
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="WP_179067343.1"
                     /transl_table=11
                     /translation="MQNFLLGGIRTKLIASFLVVALIPLLLLAFINKQTTEKALTDNAK
                     QALSAAANETANRIDAFIDANLNAVRVEAILPGLARYLSLTPKQRDDSPEMQLAIETLI
                     RLSRKDMVNVISYALLDLNGKNVLDTYTLNIGKDESVQDYFKNPLQTGLSFVSSMKRSP
                     IIPELVTLFFSSPVRNAKKEILGILRVSYNATVVQQLVTRQTERAGAKSFAILLDENKI
                     YLAHSTAPELLFKSIVPLPANLLMKLQKEERLSNFPVKELTTNDLELQKALDNKQSYLI
                     ASLSAAGNQVNLIAIASLKYKPWSVLFAQPLAVALAPVEKQIRDTMFLFAFIAGIVTII
                     ACAVGQLLTRPIIHLTNIVSQFTAGNLDIRTKNNSKDEIGQLAKSFNNMALQLQTSFET
                     LEQRVQERTAELAIAKEKAEVANQAKSLFIANMSHELRSPLNAIMGFSQLMLRAKNLPP
                     KQYDNAVIIYRSGDYLLTLINNILDLSKIEAGKTTLKSSDFDLYRLLYDLEDMLHLQAS
                     NKGLKLTFQCSENVPRYIYSDVLKLRQVLINLISNSIKFTEEGEITVTVNNSSEEFTDI
                     LNLDFQVHDTGVGISAAELPKIFNAFSQAKAGKESHEGTGLGLAISRKFVQLMGGDILA
                     KSQLGKGTTFKFNIQATLGQKINDHTLGLYSKVLGIAPGQPIYKILIVDDKSINRQLII
                     QLLEPLGFEIKEASNGKEAITIWDEWEPHLIWMDMRMPVMDGYEATKYIKSTTKGNATA
                     IIALTASVLEEEKAIVLSAGCDDFLRKPFAEHTIFDTLTKHLGVRYIFAENNPVNLEYI
                     EKNDLTSDNLTCMSQEWIHQFYEAALEANTNLIIELIREIPQTETFLIQSLTKLVRKFE
                     LEQLVNLVEPLLM"
     gene            16308..17675
                     /locus_tag="FD723_RS22485"
                     /old_locus_tag="FD723_22405"
     CDS             16308..17675
                     /EC_number="2.7.7.65"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015215879.1"
                     /locus_tag="FD723_RS22485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22405"
                     /product="diguanylate cyclase domain-containing protein"
                     /protein_id="WP_179067344.1"
                     /transl_table=11
                     /translation="MNFDSYKENKGNILLVDDLPENLQLLSDSLIQLGYTVRSVTSGRM
                     ALKTVKVKQPDIILLDIKMPEMDGYQVCKTLKADEDLRTIPVIFVSALDDVFDKVTAFE
                     LGGIDYITKPFQMEEVVARIENQLTIQRQQRLLEQENIKRRETEEILYQSRAMLASILN
                     SSLDGIAAMQAVRNPATGDIEDFRCLVVNPVIARAFGRNREEMIGKLTLKKFLTTFKPE
                     LFNLFVNLVETGEPIKRDFYHPLGNSCWYHFVAVKLGDGFAITIRDITGRKQIELALKD
                     ANQKLEQLVNVDGLTQVANRRCFNGRLQAEWKRLAREQQPLSLILFDVDKFKLYNDYYG
                     HLAGDDCLIRIAQTVQQTVHRPTDLVARYGGEEFSVLLPNTDLAGAIKVAQSIQQVIHA
                     QAIPHVKSDVKNIVTLSLGITSLIPVWDVKPDTLIALADRAMYNAKQEGRDRYCTN"
     misc_feature    complement(17854..17872)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 26.47"
                     /tool="antismash"
     gene            18004..18888
                     /locus_tag="FD723_RS22490"
                     /old_locus_tag="FD723_22410"
     CDS             18004..18888
                     /NRPS_PKS="Domain: TauD (11-286). E-value: 1e-49. Score:
                     161.7. Matches aSDomain:
                     nrpspksdomains_FD723_RS22490_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121: dioxygenase, TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015206659.1"
                     /locus_tag="FD723_RS22490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22410"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_179067345.1"
                     /sec_met_domain="TauD (E-value: 1.1e-47, bitscore: 161.7,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLTATQIQITPTKAPLGAVVTGIDASVAAQPEVILQLKQAWRDY
                     HVLIFKNQQLTDDQLLAFANYFGDILQQPAYIRKGETEPYLPPLVLTLANAASEESSVN
                     LAPNYRELLPHIDHDWLPAPSSGSFLYGVELPENGPDTYWVNLIQAYEELDDATKEQIA
                     GLQVRHFSSFSKLYKDEYSGPIYAAGRPAEPGERLATHPLVRTHPDTGKKVLFLNAAGE
                     VDIVDYDPVEGAKLIERLREHIKQPHYVYQHHWSKGDLLYWDNQATAHYRPEFDPNATR
                     ILKRVSIRGSRPF"
     aSDomain        18037..18861
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FD723_RS22490_TauD.1"
                     /evalue="1.00E-49"
                     /label="FD723_RS22490_TauD.1"
                     /locus_tag="FD723_RS22490"
                     /protein_end="286"
                     /protein_start="11"
                     /score="161.7"
                     /tool="antismash"
                     /translation="PTKAPLGAVVTGIDASVAAQPEVILQLKQAWRDYHVLIFKNQQLT
                     DDQLLAFANYFGDILQQPAYIRKGETEPYLPPLVLTLANAASEESSVNLAPNYRELLPH
                     IDHDWLPAPSSGSFLYGVELPENGPDTYWVNLIQAYEELDDATKEQIAGLQVRHFSSFS
                     KLYKDEYSGPIYAAGRPAEPGERLATHPLVRTHPDTGKKVLFLNAAGEVDIVDYDPVEG
                     AKLIERLREHIKQPHYVYQHHWSKGDLLYWDNQATAHYRPEFDPNATRILKRV"
     gene            19220..20296
                     /locus_tag="FD723_RS22495"
                     /old_locus_tag="FD723_22415"
     CDS             19220..20296
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0042918 - alkanesulfonate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017743614.1"
                     /locus_tag="FD723_RS22495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22415"
                     /product="aliphatic sulfonate ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_179067346.1"
                     /transl_table=11
                     /translation="MVRPQIGKYSISRRDLLYAFYGLVSFTTLVSCGKNNGSANNSSTT
                     LSTNVTNTNSKAATKLIRLGYQVSGDLTHEKGAIEKRLAPQGIGVTWSQFVSGPPLLEA
                     LNVGSIDLGPAGETPPIFAQAAGTNLIYVVNTPPGTGEGSAIIVLKDSPFQTLASLKGK
                     KVAYSRGTAQTFFVVKALEEVGLKISDVESVNLPVADGRAAFLNKTVDAFVEGDPNLIK
                     LQREGSIRVLRNAQGIKTPGGYYLASRDFATKNAELLKAILSEYYEVGQWANKNRRAAA
                     EILAPKVKTDVDTMELTLARRKYDMKPITEEVINAQQKVADLLYQLKVVPKSVDVRGAT
                     LTSQEYAAITPDAVRNKA"
     gene            complement(20391..20789)
                     /locus_tag="FD723_RS22500"
                     /old_locus_tag="FD723_22420"
     CDS             complement(20391..20789)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012412465.1"
                     /locus_tag="FD723_RS22500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_22420"
                     /product="DUF6335 family protein"
                     /protein_id="WP_179067347.1"
                     /transl_table=11
                     /translation="MAEKNHPDKIKTKDLPQEITESYGTGVKDLPGYNIGGRSIKAERD
                     EYTETSPELTGGDVDAYWQDADAVGDEAVGGSTATPDQNVTEELEIAVGLEMDDSEFLH
                     TNDILEQRDGDRWELDPKSSEDYQNRRE"
     misc_feature    complement(20817..20828)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.34"
                     /tool="antismash"
     misc_feature    21025..21034
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    21561..21577
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 25.0"
                     /tool="antismash"
ORIGIN
        1 agattgggta gaagaatgta acaaagataa attggcgctt tgggcaactt ttcattccga
       61 atgggtgtca cgcgatcgct tcttagccaa atgcctcaat ctagacaaca aaaatgtcaa
      121 atttagcgtt ggagttgtcg gtttttccaa gtttaaagca gaaatagcag ctttacgtca
      181 agagttacca aaccacgttt atttgtggat taatgctgtg aaagctgaac tgactaattt
      241 atcaccagaa aatcgagaat tatttcaatc tatcgatcca ttatatgaat taaatactca
      301 acattatcct agctttgggc attcttgtca ggctggaaaa tcagtgattt ctgttgatgg
      361 tgatgggaca atgtatcgat gtcattttat taaagcagca attggtaata tttatgattc
      421 tgactgggaa gcagctttgt ttgaacaacc ttgtaccaac caaacttgtc actgtcatat
      481 tggttatgtt catctagaat atttagaaat gaataaggta tttggtgctg gtattttaga
      541 aagaattcct gataattggg ttaatcaaaa ttgtactgta atataacctg cattccgcta
      601 tataccgatt ttagcatctg cctgacatgc caattcttgt ctagatagtt tacgcagtgc
      661 gggtagagta tcaataattc tcggttaagg ggaaaaggga aagaaaaaac ctttaaccca
      721 aacccagtac cctttacccc aaacccgatt tcgagttaaa aatgcaaaac ctgagaagta
      781 ttgggtagag tattctgaat tctgactcct ttttatagga aaaaagcctg gaataatttc
      841 tagacaatca tttcaggctt gagcctcttc aattttataa ttattaaatc cgctttaata
      901 tctgcggaat gtgggttgta aaaatgcttg gactggagtg ctaaatttgt cacttgtcgg
      961 gaacttgcaa tggcagcgac cattatactt ttttatagcg gtgatttagc gatcgcagcc
     1021 caaactctat gatgaacttc aagaatttct gtaggatatc ttgtttcgag taatgtcgcc
     1081 aattcctggt caaatacttc taccaattct tgtgtcaagc tggctcccac accggcacta
     1141 gcacgaattc gtccccgcca agcctcgtgt gtataaggta caaatacatc gtaagaaaat
     1201 gtgcggattt ctcgaaatcc tccttcgcca atatcttgta accacagggg atgcaagcca
     1261 ttaccgccgc ccatattcca ggcgggatta tgagcctcga tcagtcgttc tgtggcttca
     1321 acgacattac cttttaaagg tatccaatca aaatgtgcga tcgcgatcga gccatttctt
     1381 ctcaatatac gagtaatttc ctggacggca cgcggacgat caaaccaatg ccaacactgt
     1441 ccagctgtca ccacatcagc actggcatct ggtaactcgg tattctcagc agttgcgact
     1501 cgataatcta cttggagttg ggcagattcg cttaactgtc tggcttgttc taaaagtgac
     1561 actgatgggt cgatgccgat tacataagca cctctatcag caaagccccg cgctagtgtt
     1621 cctgttcctg taccaaggtc aacaatattc tgccctggta aacctatacc atattcagac
     1681 agtctattaa ataatgaact gggaaagcca gcgcggtgtt ttgcataatc agtagcagtt
     1741 gcaccaaaat caattttcat acctataaaa ctattcttgt aacaattgtc taggctagaa
     1801 gttctctacc cacggacgta gttctacttc ccaagtccaa gcactgcgcg gttggcggag
     1861 aatgctgaga taagtttgag cgatcgcatc cgggtcaaga gtactatcag gattatctac
     1921 tggatcttgg cgaactgctg aacggattcc accatcaatc acaaaatgcg ctacatggat
     1981 attctttggt gctaattctc tagcaatact ctgagccaaa ccgcgcagtg caaatttccc
     2041 cattgcaaag ggcgcagata gcggataacc tttaacactg gctgaggctc cagtaaaaaa
     2101 tatagcaccg ccgccaagtt gcaaaaacct tttggtagca gcttgggcta caagaaaacc
     2161 accataagca gttatatcta aggtttttgc cacttcacca ggatctagat cgacaagagg
     2221 cccccgcacc cgaaaactgg gattgtaaat aacaacattc ggggaaccga ctttattttc
     2281 gatatcaata aataactgtt ctacttcatc cggctttgag gcatcagcgg cgaaactaac
     2341 tgccccaatt tcactgctca attgagtgag tttttcaatt tggcgagctg ctaaagctac
     2401 ggtaaatcct tctttggcaa ataggcgagc taaagaagcg cttagtccat tacctgcacc
     2461 gacaattaaa gctgttgttg ccataaatta attatccatc actgaagata actgtgaatt
     2521 gcccttagtg ggactttgac caatttgcag tacacaaact gcggcaatca gacagagaac
     2581 gcctgataaa ataaacgctt gtaaataact acccgtccaa gttctcaaga ctccggctcc
     2641 gaatgctgct gtggctgcac caagctggtg tccggcgaca atccaaccga acatcacgcc
     2701 gacattttct ttaccgaaga cgttggcaac cagacggact gttggtggta cggtagcaat
     2761 ccaatcaagt ccatagaaga cggcgaaaat ggaaagccca tagaaggaaa agttgaaact
     2821 gaagggcaag aaaatcaaag acaaaccccg cagtccgtag taccaacaca ataagtagcg
     2881 attgttccag cggtcagata gccaaccgga catagtagtt ccgaaaaaat cgaataatcc
     2941 catgattgcc aaaagacccg ccgccttgac ttccgggata ccgtggtcaa tacaagcggg
     3001 aatcagatga gttccaatta acccatttgt gctagcacca cagataaaaa agctaccaaa
     3061 taacagccag aagtcgcggt tacgcattcc cagccagagg gcgttaagag tggaggcgat
     3121 ggaattgact ttgggctgta acacttctac agtttcgctg gtgtcgccaa aaggtcgcaa
     3181 accaacatcc gccgggcgat cgcgcataaa agctgcgatc gctggaataa ttaaaagtgc
     3241 tgcaccagtc agagctagag ccgcaattcg ccaaccaaag cgatcggcga ctgaagccag
     3301 catgggtaaa aacactagtt gccccgtagc tgtactggca gttaagatgc ccagaactag
     3361 accccgcttt gacaaaaacc agcgattgac gacaatagca cccaaaacca gggcgataac
     3421 tccgctacca gaaccgacta ctacacccca cagcaagact agttgccaag acgctgacat
     3481 caaagtggtt aaaccgacac cgagagcaat gatagcaagc gaaaatacca tcatccgccg
     3541 aatgccgatc cgctccataa cggtggcagc aaaagggcca attaatccgt agagtaccaa
     3601 gttaatggag attgctaaag atatagttgc tctactccag ccaaactctt gttccagagg
     3661 cactataaaa actccaggag cagagcgaat tccggctgcc actagcaagg ctaagaatgt
     3721 taaacctgca actatccagc catagtggaa cgaacgacgc gcgaggaagg agggtaagga
     3781 catggttgag gaggggggag tgagatgagg gagtagggga ggcaggggga gcaggtttaa
     3841 agactcgttg gcgagtatca aagactcatt cacgagtatc aaagactcgt tggcgagtat
     3901 caaagactca ttcacgagta tcaaagactc gtcggcgagt atcaaagact cattcacgag
     3961 tatcaaagac tcgtcagcga gtatcaaagc ctcattcacg agtatcaaag actcgtcggc
     4021 gagtatcaaa gcctcattca cgagtatcaa agactcgtcg gcgagtatca aagcctcatt
     4081 cacgagtatc aaagactcgt cggcgagtat caaagactca tcccctattc tccatgcccc
     4141 attccgcatt tataaaaaac taccctgcat aagggttgcc aattctgtct acagagacat
     4201 tagaggagaa tggcaaacga ccgggattta agcgtggttc ggctgcatag ccaacaggga
     4261 ctaaaacagc gatcgctaaa tctggattat ccccagcacc aattacttgc tttacctgat
     4321 cctcaatcca accgttcata aaacaagtcg ataatcccag actttctgcc gctaacacca
     4381 aatgggtagc agcgataatc gcatctttga tggcatactc ccgttgcttg tctcctagcc
     4441 cctgttgaaa ttgcggaata gcagttttaa aataatttgc cgtaccttca ttccaggccc
     4501 cagttgcaag agcctgttca atgatcgggt tcaagtttgt ttcagatgca gttgcatcag
     4561 cagcaaacac aaaggtaact ggtgcttgga caatttgctg ttgattccat gatgctgctg
     4621 ataaggctgc tttttgcgcc tcatcttgca caagaataat ttgccagctc tggatattat
     4681 agctgctggg cgctgccacg gttaactcta ccagttgttt gagcaattct ggggcgatgg
     4741 ggtctgtttt aaaagttttg attgaacgac gtttagcgat cgcacttggt acatctaaag
     4801 gttgggtttg gatgacggta ctcatgagat tctcctgata gttggattat gaccaaacaa
     4861 ttcgtaatta gcatacaagc gaatgtattt attcatgaaa caaaaataaa aattattcct
     4921 tgtttccgaa taaacaactt tacagtacgc tcaagggaaa attacgaatt aagctgttgg
     4981 aaatttaacc tgcatattac ctggaattaa aactcttgtg gaatgggcaa caatgagcgc
     5041 cctagttatg caaattaaaa gtacattagc ttacgaatta cgaattacac gttagctaca
     5101 ggttcattag cagtcgacca aaatggatag tctgtatatc cctgttcacc accaccataa
     5161 aagcttgctt gatttggttg atttagtggt gcattcaaag ccaagcgtcg gggtaaatcg
     5221 ggatttgata taaataatgt gccaaaggca actaaatctg cggctttgtt tgccagtaca
     5281 gcatcacctt tttcacgggt ataaccacca ttgacgatga gagtacctgt aaagcgatcg
     5341 cgtatatgac tggtgggtac aattattccg ccatgtctga tgtctgcctc tgttgcctca
     5401 taaatatgta gatatgccaa attaaactta ttcaatgctt gagccgcata accgaatgtc
     5461 tccagaggat tggagtcatg gatatcgtta aaagtcccac tgggagagaa acgtacccca
     5521 actcggttag aatcccacac actagttacc gcttctgtta cttccaacag gaatcgggcc
     5581 cgattttcaa tgtcaccccc atatttatct gtacgttgat tagtaccatc ccgaagaaac
     5641 tgatctatta aataaccatt agctgagtga atttccaccc catcaaaccc agccgctaga
     5701 gcatttgccg ctccctgacg gtactgttcg acgatctgcg gtatttccga tgtttctaaa
     5761 gcacggggag taacaaaagg ttttggcccc tcataagttg aagcctcacc tttaggagcg
     5821 atcgcagaag gtgctacagg taaaactcca tttggttgta agtctggatg agaaattctg
     5881 ccgacatgcc atagttgcaa gaaaattctt cctccgtgct gatgtacggc atcggttact
     5941 aacttccatc cctccacctg ttctggtgaa tgaattcctg gtgtcgcggg atagccttgc
     6001 ccttcaggag ttacctgtgt tgcttcagaa ataatcagtc cggcggaagc acgttgagca
     6061 tagtaagtag cattaagttc gtatgggacg tttcccttag ctgccctatt tctggttaag
     6121 ggtgccatca ctatccgatt aggtaattcc agattcccta attgataagg agagaataag
     6181 ttgatatcag ctgtcattgg ttatatctcc aaattatttt acattgggca ttgggcattg
     6241 cctcgttccc agtctccgac tggaaacgag atttgaaaag ggtttggtct attgctgtgc
     6301 ccctacaaca gatatacttc aaatactaaa caatcgatcg aataacgcca ccatctaccc
     6361 gcaaagctgc accattagtt gctgaggcta cgggactaga aagataaact acgatcgctg
     6421 ctacttcttc attagttgca aagcgtttaa tcaaggaagt tggacgcaca ttttgaaaaa
     6481 attcagcctc aacttctgtt ggactgatac cacgttcctg tgctagttga gaaataaact
     6541 cttcaacgcc ttctgaacgg gttggccctg gtaggactga gtttactgtg actccagtgc
     6601 caacagtcat ttctgctaga cctcgggcaa tggctagttg cgctgtctta gttgtgccat
     6661 agtgaatcat ttccactggg atctgaatag cagattcgct ggagataaaa attatccgtc
     6721 cccagttttg ctctagctgc ttttgcagat attgccgact caagcggact ccactgagaa
     6781 cgttaacctc aaatatgttt aaccaatctt gatcagtaat atcaaagaag gtttttggct
     6841 cataaatacc taaattgttg atgagaatat caacgtgagg aactttttca aaaagttgtt
     6901 ctacccctga tgctgtgccg gtgtcagcaa caacaccaga aactttcgca tcgggtgtaa
     6961 aatgcttaat tttagcgatc gcttgagcta ctcttgcttc agaccgacca ttgataatta
     7021 ctgatgcacc ctcttgagct aacccaagag cgatcgccaa accaatgcct gcggttgagc
     7081 cactcaccaa tgcagattta ccatgcagtt tcaagtccat ttcgctcttt ccccgttagt
     7141 tgaaacagaa tgatttggga ctggggacta agaagtaggg ggagattagg gagatgaggg
     7201 ggataaacaa aactcctcac tcctaactcc tcactcctca ctcctaactc ctaactcagc
     7261 actcaaatta aagatgctgt gctaaggtct tattcaaggt agtttttggg actgccccga
     7321 cgacagtatc aacctgccga ccgcccttaa aaaccatcag cgtcggaatg ctgcgaattc
     7381 cgtaatggct agcgacagta ggattttgat ctgtgttcag cttcacaaat ttcacctgtc
     7441 cttcgtattc agcagcaact tcatcgacga ctgggcccac catccggcaa gggccgcacc
     7501 aaggggccca aaagtccact aataccggaa tttcactttc caagacttct tgcttgaatg
     7561 tggcttctgt gacatttgta atggatgaca taaattgcct tcctaattaa ttctattatt
     7621 cgataatatc gaataataaa aatatatgcc acctgatgag ataatgcaac tatgagattt
     7681 ctttatcatc cagatagaaa aaatatttct ttaccgggcg tattgtatgc attgggcgat
     7741 ccggtgcggt tagagattgt gcggttgctg gcgactgagg gggaacaatg ctgtgcgaga
     7801 tttgattttg cgatcgctaa gtctacgatg tccaatcact tcaagatttt gcgggagtcg
     7861 gggatagtct tgacacgcaa agaagggaca caccatatta acatactacg gcgtgaagat
     7921 ttagagatgt tgtttccagg gttactggat gcagtcttga aagctgctca accattgcct
     7981 gttagccctg ttagtactaa acaaatagct tcaagaattt aggggtattg gtcattgggt
     8041 atgaattgtt taagaatctt ctcgtttttc tttctgtatt tctaaatcag caaagatatc
     8101 gtgttgttct tgaaaagtcc ttggagtgtg agataaacct aaatctgtag agagtaaatc
     8161 aataccatcg ataattttgg gtatctgagc ttgatcgact tgcagactca gaaagcattt
     8221 ctccctgtaa tctggtcttt cttgaaagcg tgcgatgtct acgacgggct acgcctacgc
     8281 tcttttcaaa gggcgcataa cctgatatgc tctttcagcc ttctcaattg atacttgagg
     8341 tattggcgat cgcagcctga gaactgctag atcgattaaa tctctagcct caacgctgtc
     8401 atcggcgtaa cggtcagaat ttgacagcag cttagaggta aaacaatcat tgaagcttaa
     8461 gcagagaaca agtgactact ttggatatct tggtggatct agttgaaaac gagtttcggc
     8521 aataatttca attttaatcg gcacatcatc cacaaaaaca cttttatttt agattaaaaa
     8581 ctggtattat ccgagctagg ataaactctt cctttccaag cgccgccgcg cccttgccaa
     8641 tgacggagtg ctgagtctaa agtcattaaa gtataaagaa aagcgatcgc aggtaagctc
     8701 aacgcgaacc agggagaaca tttataaaag cggatcgtcg ggtagtaagc gacagtcatc
     8761 aacagccatc cgaataaacc tgtaaatgcg atcgcccaat tgccccaaac tgcacctaga
     8821 atcatacata caggcggagc taaataaatc agaggcattc ctaccaaagt tcccaatagt
     8881 agtaatggcg aataattcag ttgggtatag gcagtacggg caaccatatc ccaaatggtc
     8941 gccagggaat catagggacg caaactgcga gtcaagctac tcaaccccag ccagatacga
     9001 ccttggctgg ggattaggta ttgagcattg taggtatggt tattttcttt gtctcccctg
     9061 ctcccctgct cccctgctcc cctgctcttc ttaacagcct gagccaaggc gcaatcgtca
     9121 attaaagctt ggcgaatcac ttggatacct ccaattcgct ctaaagcttc acgggcgatc
     9181 agaatagatc ccccggcggc ggcggctgtg ggattgttgg gattattcac ccagcgaaaa
     9241 ggatagagtt tttggaagaa aaagacgaag gctggaatta aaagtttttc ccaaaagctt
     9301 tcacacctga gtcgtaccat taccgaaacc aggtctaaat cttcttggac agctttagca
     9361 accagtcggc ggagattacc aggatcgtgt tcgatatctg cgtcagtcag caaaaaataa
     9421 tcaggtgcaa gtttattcgc gctcttgata ccttgctcaa ctgcccaaag tttccctgac
     9481 caaccaggag gcagtgattc acctgagata atatgcagtt gttggggttt gccgacagcg
     9541 tgtgcaaccc cttcagcaaa atttgctgtc cggtctgtgc tgcgatcgtc caccaaaaat
     9601 acagtgaaag aaccaggata atcttggagt aggagcgatc gcaaactagt tggtattaac
     9661 tcagcttcgt tacgcgccgg aacgacggca caaaccacag gtaacgattt tagagacgtt
     9721 gtatacaacg tctctacctc taattgctgg tctgtccgcc aaaattgccc ccaaaaacat
     9781 agtaacccta accaaattgt caaggataag agcatcaatc ctaatacaat tacatccatg
     9841 accgtcgctt cgctccaatt caaaattcaa aaaaaagaat gatctattgc aaatttttag
     9901 tgactcagac acaatactat gtctactgat ataggaaaat ttttttatcg gattgccgta
     9961 ttcaaaagta gggttgggtg ttgaggttaa ataggatttg atgcaaacac aagacagggt
    10021 aaaagtcaat caagtcgcag aagcgatcgc agctagccaa gaatatctgc tttcaattca
    10081 aaatccggca ggttactggt gggcagagtt agaatctaat gtcaccatca ctgctgaagt
    10141 cgttctcctg cataaaattt ggggaacaga ccaaaccaga gctttacaca aagttgaagc
    10201 atatttgcgt caagagcaac ggcagcacgg cggctgggaa ctttactacg gtgatggtgg
    10261 agaactcagc acctcggttg aagcttacat ggcgttaaga cttctaggtg taccagtaag
    10321 cgatccggcg atgcttcggg cgaaaacttt tattctccaa cgaggtggga tcagcaaaac
    10381 tcggattttt accaagttac acttagcctt gattggttgc tacaactggc gcggtattcc
    10441 ctcgctacca gcttgggtga tgctgttgcc gaaagctttt ccagttaata tctatgagat
    10501 gtctagctgg gcacgttcca gtacagtacc attactgatt gtatgcgatc gcaaacctgt
    10561 ttttctcacc gattcagcga tcaacctaga tgagctatac gccgaaggtg tcgatcgagt
    10621 ccagtgggaa ttaccccaaa gtggcgattg gacagattta ttcctcaccc tcgatcgggg
    10681 gtttaagttg gcagaaagcc ttaatttagt accctttcgc caagaaggca tcaaagccgc
    10741 cgaaaaatgg attttagagc gccaagaagc tacaggtgac tggggcggca ttattccggc
    10801 gatgctgaat tcaatgctgg ctttgcggtg tctggattat gaccgaaacg atcccattgt
    10861 ggaacgaggt ttgcaagcaa ttgataactt tgccattgaa acagacaata gctatcgggt
    10921 acagccttgt gtttcacccg tctgggatac agcttgggtg atgcgtgctt tagtagaatc
    10981 tggctttgca ccaaatcatc cggctgtagt caaggctgga gaatggttgc tgcaaaaaca
    11041 aattttagat tacggagatt gggctgtcaa aaatcgccaa ggaaaaccag gggcttgggc
    11101 gtttgagttt gagaatcgct tttatcccga tgtagacgac tcggcggtgg tggtgatggc
    11161 gctacattta gcgaaactcc cgaatgagaa aattaagcaa gctgcgatcg ctcgggcctt
    11221 aaactggatt gcatctatgc aatgtaaacc gggtggatgg gctgcttttg atttagacaa
    11281 cgatcaagat tggctcaact cgattcctta tggcgactta aaagccatga tcgatccaaa
    11341 caccgcagat gttacggcta gagtgctaga aatgcttggt gcttgtgatt tgtcaattga
    11401 tagtgataat ttagagcgat cgcttactta tcttctgcac gaacaagaaa ccgaaggctg
    11461 ttggtttggt cgttggggtg taaattatat ctacggtact agtggcgttt tatcagcctt
    11521 ggcgttaatc gatcctcaaa ggcataaact cagtatagaa cggggagcta gttggttagt
    11581 tggctgtcaa aacccagatg ggggttgggg tgagacttgc cgcagctaca acgatcctag
    11641 tctcaaagga aaaggaaata gtactgcatc tcaaactgct tgggcaataa tagggttaat
    11701 agcagcaggt gaagccactg gtaaattagc tcttgaggtg attgagcggg gaattagcta
    11761 tctagtaaca actcaaaaac ccgatggtac ttggtttgag gcagacttta cgggtactgg
    11821 cttcccttgc catttttatc tcaagtatca tctgtatcaa caatactttc ctttaattgc
    11881 gctaggtcgt tatcaagcag taattcaaaa aggttagtta attagacatc tggtgaaaaa
    11941 gaattgtttt gacgtagcag tgctacgtct ctacaagggt tttgaaatta tgcaagatca
    12001 ttttcatacc tgaattcagc aacgccagtt ttttgttgtc aaaccaagga gaataattgt
    12061 ccgcatatcg gcggttgttg ctgctaattg gtcaagtgtg atcgcatacc tcaaacaact
    12121 gctacaaacc accatgaccc gttccactaa ttgcgatcgc ctctcaatgc agttttaggt
    12181 ttttcctaat taatgttatg cactcaaaat ttaccatcag aacaatacga caatactggt
    12241 attatttatc atagtcgaaa ttatattttg atattaatta ataatatttt tgatttatcg
    12301 aatgtttaaa ttactcagat accttagtat ttttctgatt accgcctgtt tgctatttgc
    12361 ttgtaattct tcagcaccga ccaaattaaa acgccctccc ttgaaaatac catcggcata
    12421 ttttgttggg gagtatccaa gtatcattgc tcaagaaaaa ggatttttca aagcccaagg
    12481 ggtagatgtg gaactaattc ataaacgata catccaattg gtacaaggaa atttaagtgc
    12541 gggtaaatat gatggtgcta tatcttcttt gggaggtttt ataatcttga gtgccacaaa
    12601 tccagatata caaggcgtga tggttgtaaa tgaatcaaca ggagcagatg tggtagtcgc
    12661 tcaatcacca attaaaaccg ttgctgactt gaaaggtaaa aagctgggtg caaatctagg
    12721 tggttttagc gaagttttcg tgactgagat gttgaaaact gccaacttaa gcagcgatga
    12781 tgtaaacttg gttaaattag aggcttcaga aattcctcaa cgcttaaaaa ataatgatat
    12841 tcaagccgga cacacttggg aaccctatct ctctgaagca aaaaaaaaat tagggggaca
    12901 tatcttattt accagtaaac aaacccctgg cttgatttca gatatgatgg tctttcgcgg
    12961 tgagacaatc cgcgatcgcc cggaagatat tcgtgcattt atccgaggat ggctgcaagc
    13021 cacgacctac tggaaagcaa atgttcagga aggaaatgct atcatcagca aagctttaaa
    13081 aattcccata aatacaatct ctttggaggg agtaaaccta actgatttag atgaaaataa
    13141 aaaattattt caatctagta accctcactc catttacaaa actgccaaga tatatgcaga
    13201 cttttttatt cgctctggaa acgtgacgcg cattcctgag ctaaaaagtc tgttcaatcc
    13261 ttctttctta aattcttcct cttaagttta gaggttgttt ataaagcaat acgcttggat
    13321 tagggcaaaa tgttgcaaaa aaattgtagg ttgcgctctg ctccacccaa cctacgtcta
    13381 atgcactatc ttaaacttac caccctacta cttaagattt actttataaa taaatagcct
    13441 ctgaaagcca tgcagaattt ccttttgggc ggcatccgta caaagctgat tgcctcattt
    13501 ctcgttgttg ctttgattcc gttgctgtta ttggcattta tcaacaaaca gacaactgaa
    13561 aaagcactaa ctgacaacgc aaaacaagcc ctatctgcgg cagctaacga aaccgctaac
    13621 agaatagatg cctttattga tgcaaatctc aatgctgtgc gcgtagaggc gattttacca
    13681 ggtttggcac gctacctcag cctaactcca aaacagcgag atgacagccc cgaaatgcaa
    13741 ttggcgatag aaacattaat ccgtcttagt cgcaaagata tggtcaatgt tatctcttat
    13801 gctttgcttg acttaaacgg gaaaaatgta ttggatacat atacattgaa cattggcaaa
    13861 gatgaatcag ttcaagatta ttttaaaaac ccattgcaaa ctgggttatc ctttgtttct
    13921 agcatgaagc gatcgccgat aattcctgag cttgttactc tcttttttag tagtccggtt
    13981 cgcaatgcta agaaagagat attgggtata ttgcgtgttt catacaatgc tactgttgtt
    14041 cagcagttag tgactcgaca aactgaacgg gctggggcaa aatcttttgc tattctttta
    14101 gatgaaaata aaatttatct ggcacatagt actgcacccg aattgctgtt taaatcaatt
    14161 gtgcctctgc ctgccaatct tctaatgaaa ctgcaaaagg aagaacggct gtctaatttt
    14221 cctgtcaaag aattgacgac taatgactta gaacttcaga aagcattgga taataaacag
    14281 tcgtatttaa ttgcatcttt gtcagccgca ggtaatcagg ttaatttgat tgcgatcgct
    14341 agtttgaaat ataaaccttg gtctgtattg tttgcccagc cccttgctgt ggccctagca
    14401 cctgtagaaa agcaaattcg tgacacaatg tttctatttg cgtttatcgc tgggatagtg
    14461 acaattattg cttgtgctgt tgggcaactg ctaacaagac caataattca ccttaccaat
    14521 atagtttccc agtttaccgc aggtaactta gatattcgca ccaaaaataa ctcaaaagac
    14581 gaaataggcc aactagcaaa atcatttaac aacatggcac ttcagttaca aacctctttt
    14641 gaaactttag aacaacgggt acaggagaga acagcagagt tagctattgc aaaagaaaaa
    14701 gctgaagtgg caaatcaagc taaaagttta tttattgcca acatgagcca tgaattgcga
    14761 tcgccactca atgcaattat gggtttttct caattaatgt tacgtgctaa aaacttacca
    14821 ccaaaacagt atgataatgc cgtaattatc tatcgtagtg gagattatct cctaacattg
    14881 attaacaata ttcttgattt atcgaaaata gaagcaggta aaacgaccct caaatccagc
    14941 gatttcgatc tttatcgctt gctctatgat ttagaagata tgctgcatct acaagcaagt
    15001 aataaaggct taaaattaac atttcaatgt agtgaaaatg ttccacgtta tatttacagt
    15061 gatgtcttaa aactccggca ggtattaatt aatttaatta gtaacagcat taaatttact
    15121 gaagaaggag aaattactgt aacggtaaat aatagcagtg aagaattcac agatatttta
    15181 aatcttgatt ttcaagtcca tgatacaggg gttggtattt ccgcagcaga attacccaaa
    15241 atatttaatg ctttttctca agcaaaagcc gggaaagaat ctcatgaagg tacgggtctg
    15301 ggtttagcga ttagtcgcaa gtttgtgcag ttgatggggg gagatatttt ggcaaaaagt
    15361 caattaggaa aagggacaac ttttaaattt aatattcaag ctacattagg tcagaaaatc
    15421 aacgaccata ctttaggact gtattccaaa gtattgggaa ttgcaccagg gcaacccata
    15481 tataaaatat taatagtaga tgataaatct attaatcgac aattaatcat tcaactttta
    15541 gaacctttag gttttgagat caaagaagcc agtaacggca aagaagcaat aactatttgg
    15601 gatgaatggg aaccgcactt gatttggatg gatatgcgga tgcctgtgat ggatggttac
    15661 gaagccacta aatacatcaa atcaactacc aaaggcaatg ctactgcgat aattgcgctc
    15721 acagccagcg ttttagagga ggaaaaagcg atcgtgcttt cagccggttg tgatgacttt
    15781 ctgcgtaaac cctttgctga acacacaatt tttgatacac tcaccaagca tcttggtgta
    15841 aggtatatat ttgctgaaaa taatcctgta aatttggaat atatagaaaa aaatgattta
    15901 acatctgata acctaacttg tatgtctcaa gaatggattc atcaattcta tgaagcggct
    15961 ttagaagcaa atactaacct gataattgaa ttaattagag aaattcctca aacagaaact
    16021 tttctaattc aatctttaac aaaacttgtc cgtaaatttg aacttgaaca attagttaat
    16081 ttagtagaac ctctattaat gtagggacaa ttattaaaaa ttaaaaacat ttcagacggg
    16141 ggtctaaatc ccaaatgaaa tggatgctac tacatataga tgtagtggtc ttaaaccttt
    16201 taatttacga taaattgccc ctactccttt gagccaatta atgacaaagc ttacatggta
    16261 atttaaattt gaggagttga ttgatttagc aaaacccata atcagcaatg aattttgatt
    16321 cttacaaaga aaataaaggt aacattctcc tagtagacga ccttcctgaa aatttacagt
    16381 tattaagcga ttctctgatc caactcggct acactgttcg cagcgtcact agtgggcgga
    16441 tggcactgaa aacagtaaag gtgaaacaac cagacatcat ccttttagat atcaagatgc
    16501 cagaaatgga tggctatcaa gtttgtaaaa ccctcaaagc ggatgaggat ttacgcacta
    16561 ttcccgtcat ttttgtgagt gctttagatg atgtgttcga taaagtcacc gcctttgagt
    16621 tagggggaat agactacatc actaaacctt ttcagatgga agaagttgta gcgcgcatag
    16681 aaaaccagtt aaccattcaa cgccagcaac ggcttttaga acaagaaaat attaagcgca
    16741 gagaaactga agagattctg tatcagtcaa gagcaatgct ggccagcatt ttgaatagtt
    16801 cacttgacgg tattgccgct atgcaggctg ttcgtaatcc cgcaaccggg gatattgaag
    16861 atttccgttg cttagttgtc aacccagtca ttgctagagc gttcggccgt aaccgtgaag
    16921 agatgatcgg caaattgaca ctcaaaaaat tcttaaccac ttttaagcca gaactcttta
    16981 atctctttgt taatctcgtt gaaacagggg aacctataaa acgggatttt taccatccat
    17041 taggcaattc ttgctggtat cactttgtcg cagtaaagct aggtgatggg tttgctatta
    17101 ccatacgcga cattacagga cgtaaacaaa ttgaactggc tctcaaagat gcaaatcaga
    17161 aactagaaca actggtaaat gtagatggtt tgactcaggt ggctaaccgt cgctgcttta
    17221 atggacgact gcaagcagaa tggaaacgcc ttgcacgaga acaacaaccc ctgtcactga
    17281 ttttattcga cgttgataaa ttcaaacttt acaacgatta ctatggtcat cttgcaggcg
    17341 atgattgtct aattaggata gcgcaaacag tgcaacagac agttcatcgt cctactgatc
    17401 ttgtggcgcg ttacggcgga gaagaatttt cggtactcct ccccaatact gacttagcag
    17461 gagcaatcaa agtagcacaa agtattcagc aagtaattca cgctcaagct attccccatg
    17521 taaagtctga tgtcaagaat atagtcacac ttagtttagg tattacttct ctcatccccg
    17581 tttgggatgt taaaccagat acacttatcg ctttagccga tagagctatg tacaatgcca
    17641 aacaagaggg gcgcgatcgc tattgtacta attagacatc tggcgaaaat taaataatgc
    17701 attccctgaa aataaaacct ttttagggac aattcatgta gacgcatttg cggagcatct
    17761 cctagagaag cggcttcccg caggcagggt attttcccta caccaatttt ttagatatct
    17821 cttgaaatat tttttacagg caaattaatt ttttctgggt gtttatccag tactcacaga
    17881 tatgtaaact tattgcctct cacttgatta attctttaca caatctgtat tatgtgcata
    17941 tactactttt actctatcga gttaccgtag tatatacgcg ttaagtaagc aaagagaact
    18001 tttatgacac tgactgcaac acaaattcag attacgccta ccaaagcccc tctaggagca
    18061 gttgttactg ggattgatgc cagcgttgcg gcgcaaccag aagtaatcct gcaactcaag
    18121 caggcgtggc gcgattacca cgttctgatc ttcaaaaatc aacaattgac tgacgaccaa
    18181 ttattagcgt ttgcgaatta ctttggcgac attctccagc aacctgccta tatccgtaaa
    18241 ggagaaaccg agccgtacct gccgcccctt gttcttaccc ttgcaaatgc cgcctccgaa
    18301 gaaagttccg tcaatcttgc acctaactat cgtgaacttt tacctcacat cgatcatgac
    18361 tggttgcctg caccatctag tggttccttt ttatatggtg tagaactgcc tgaaaatggc
    18421 cccgatacct attgggtgaa tttgattcag gcttatgaag aactagatga tgctactaaa
    18481 gagcaaattg ctggtttgca agtacgtcat tttagttctt tttcaaagct gtataaggat
    18541 gaatactctg ggcctattta cgcagcggga cgacctgctg aacctggtga acgtttagct
    18601 acccatccgc tagttcgtac tcaccccgat actggaaaga aagttctctt tctaaatgca
    18661 gctggagaag tggacattgt tgattacgac ccagtggaag gggcaaagct aatcgagcgg
    18721 ttacgggaac acattaagca accccactat gtttatcaac atcactggag taaaggcgat
    18781 ttgctttatt gggataatca ggcaacagct cattaccgcc cagaatttga tcctaatgca
    18841 acccggattt tgaagcgggt tagcattcgg ggaagtcgtc ctttctaaag ttcaactagc
    18901 taaaggttgt gaattttagt cattagtcat tagtcattag tcattggtgc taatgactga
    18961 tgactacgat ttcccccgct tgaagccggg ggatgagttc agatcgttcc cagtctgaag
    19021 actgggaatg tattccaagg ctctgcctct agtcagccca ctggaggcgg agcctccgag
    19081 aatgggttcc cagcctccag gctgggaacc agttagggca aggcttatag cttttattag
    19141 tgccattcga ctaatgactt cgatttcccc ccggcttcaa gctgggggat gagttaacgt
    19201 caagatgagg aggagaatca tggtcagacc gcaaattgga aagtactcga tatccagacg
    19261 tgatttactt tacgctttct atgggttagt gtcttttact accttagtca gttgcggaaa
    19321 aaacaacggt agtgcaaata acagcagcac aaccttgagt actaatgtca ctaacactaa
    19381 tagtaaagcc gctaccaagc tgattcgact tggctaccaa gtttccgggg atctgaccca
    19441 cgaaaaaggt gcgatcgaaa aacggttggc tcctcaagga ataggtgtta cttggtctca
    19501 atttgtttcc gggcctccac tcttggaagc cttaaatgta ggtagtattg acctgggccc
    19561 ggcaggtgaa acgccaccga tttttgctca ggccgctggt accaatctga tttatgtagt
    19621 taacaccccg cctggtactg gagaaggttc agcaattatc gtactaaagg attctccttt
    19681 tcagacattg gcaagtctaa aaggtaaaaa agttgcttat tctagaggga cggctcagac
    19741 cttttttgta gtgaaagctt tggaagaggt agggctgaaa atcagtgatg ttgaatcagt
    19801 gaatttgcct gttgcagatg gacgagcagc gtttttgaac aagacagttg atgcttttgt
    19861 cgaaggcgat cctaatctga tcaagctgca acgagaaggc agtatccgag tgttacgaaa
    19921 cgcacaagga attaagacgc caggaggtta ttacttagct tcacgggatt ttgcaactaa
    19981 gaatgctgaa cttttgaaag caattttgtc agagtactac gaggttgggc agtgggcaaa
    20041 caaaaacagg cgggctgctg ccgaaattct cgcaccgaag gttaagactg atgtggatac
    20101 tatggagtta acactggcga gaagaaaata tgatatgaaa ccaattactg aagaagtgat
    20161 taacgctcaa cagaaggttg ccgatcttct atatcaactg aaagtagtac cgaaatcggt
    20221 tgatgttcga ggggcaactc taactagtca agagtatgca gcgattacac cggatgctgt
    20281 tagaaataaa gcgtgaactt tgagggtaaa gcttgctaca aaccattgcc agcttactat
    20341 ctgttctgct catcgacttt aagaatgtac aactggctaa tgtagcaagc ttattctcgt
    20401 cggttttgat aatcttcaga agactttgga tctaactccc agcgatcgcc gtcacgttgc
    20461 tctaaaatat cgttggtatg gagaaactca gagtcatcca tttctagccc cactgctatt
    20521 tctagctcct cagtgacatt ttgatcggga gtggctgtac taccaccaac agcctcatcc
    20581 ccaacggcat ctgcatcttg ccaataagca tcaacatccc caccagtgag ttcaggacta
    20641 gtttctgtat attcgtctct ttctgcttta attgagcggc caccaatatt gtatcctggc
    20701 aagtctttca cgccagttcc gtaagattcg gtaatttctt gcggcaaatc tttggtttta
    20761 attttgtcag gatgattttt ttctgccatg atattacctc ttttgtgcat tcttacaata
    20821 acgttttcct gtcactattt tgtctaacta gagatgtata gctgagaaaa taatctatcc
    20881 cctgggaacg aagctaaact agcgatcgcc ccataagatt gtatatgtaa attcatggtc
    20941 aagcaacttg tagttgaaat ttttagttat gagttaggaa ttataaaact gagcttattc
    21001 agttgctaaa ttctcgctca taactatttt ttgaaattgc ctacctaaat gctaaacaac
    21061 aaaatattca atactagaaa taaataggta ataccatcaa tgactgacaa taacaatcat
    21121 tccggcaaga aaaaagttgc aatcttgatt gaacaggcgg tagaggatgc agaatttaca
    21181 gttccttata atggactaaa acaagcagga atcgaggtcg tagtcctggg ttcccgaatg
    21241 aatgaaaaat ataagggtaa acgcggcaaa cttagcgtcc aagctgatgg tactacaacg
    21301 gaagcgatcg cagccgaata tgatgctgta gtgattcccg gcggtatggc tcccgataaa
    21361 atgcgacgga accccaatac agtaagcttc gtacaagagg cgatacaaca aggaaagttg
    21421 gtcgctgcgg tttgccacgg cccacaagtt ttgatagaaa gcgatttact caaaggtaaa
    21481 caagtcactg ggtttattgc tattgccaaa gacatcatta acgctggtgc aaattattta
    21541 gatgagcctt tagtagttga cggtaattta attacatctc gtgaaccggg agatttggca
    21601 attttcacca ccgctatttt gagccgttta ggctatggtg gcaaagatgt cgcattgcca
    21661 aatgaaaaag acacaagtgc tgaatggtgg aaactcgctg atgcttgggg tggctcaact
    21721 aaaggtgata ttggcagagg tttaaatacc gcccttactg gtgaacgtta ttcactagaa
    21781 gcattgaata agtacttgga aaaggaatca gatagcgaag taaaatcact ctttcaagag
    21841 attattgcta ataaacaaca ccacattgaa aaactggaaa catatcttca gcatctaggc
    21901 gagaaaccct ctttagg
//
