LOCUS       NZ_CP040272            20966 bp    DNA     circular CON 31-AUG-2024
DEFINITION  Nostoc sp. C052 chromosome, complete genome.
ACCESSION   NZ_CP040272
VERSION     NZ_CP040272.1
KEYWORDS    RefSeq.
SOURCE      Nostoc sp. C052
  ORGANISM  Nostoc sp. C052
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
            Nostoc.
REFERENCE   1  (bases 1 to 7828336)
  AUTHORS   Li,F.-W.
  TITLE     Complete genomes of symbiotic cyanobacteria from bryophytes provide
            new insights into the evolution of Vanadium-type nitrogenase
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7828336)
  AUTHORS   Li,F.-W.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2019) Boyce Thompson Institute, Boyce Thompson
            Institute, 533 Tower Rd, Ithaca, NY 14853, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.4.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 84.0x
            Sequencing Technology             :: Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013393905.1-RS_2024_08_31
            Annotation Date                   :: 08/31/2024 08:18:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,527
            CDSs (total)                      :: 8,409
            Genes (coding)                    :: 8,174
            CDSs (with protein)               :: 8,174
            Genes (RNA)                       :: 118
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 104
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 235
            CDSs (without protein)            :: 235
            Pseudo Genes (ambiguous residues) :: 0 of 235
            Pseudo Genes (frameshifted)       :: 84 of 235
            Pseudo Genes (incomplete)         :: 168 of 235
            Pseudo Genes (internal stop)      :: 38 of 235
            Pseudo Genes (multiple problems)  :: 50 of 235
            CRISPR Arrays                     :: 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:15:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3427538
            Orig. end                         :: 3448504
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040272.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Fay-Wei Li, Boyce Thompson
            Institute, 533 Tower Rd., Ithaca, NY 14853, USA.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20966
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="12"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20966
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20966
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10966](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10966)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(210..1154)
                     /gene="lipA"
                     /locus_tag="FD723_RS13795"
                     /old_locus_tag="FD723_13770"
     CDS             complement(210..1154)
                     /EC_number="2.8.1.8"
                     /GO_function="GO:0016992 - lipoate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lipA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015207287.1"
                     /locus_tag="FD723_RS13795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_13770"
                     /product="lipoyl synthase"
                     /protein_id="WP_179069143.1"
                     /transl_table=11
                     /translation="MIASQQAELKSEITAMPSWLRRSIGKASEISTVQRIIKQRQIHTI
                     CEEGRCPNRGECYAQKTATFLLMGPTCTRSCAFCQVDKGHAPMPLDLEEPEKVAQAVQL
                     LGLRYVVLTSVARDDLPDQGAGHFVKTIATIRQLNPETQIEVLTPDFWGGAGIGESGQR
                     QRIEMIVKAKPACFNHNIETVRRLTGPVRRGAKYDRSLLVLAMVKEIDSTIPTKSGLML
                     GHGETLDEVIEAMTDLRAVGCDRLTIGQYMRPSLEHLPVQKYWTPEEFDQLGRLAWEMG
                     FNHVRSGPLVRSSYHAGEEGAGEAGEQGAGGRG"
     gene            1389..2024
                     /locus_tag="FD723_RS13800"
                     /old_locus_tag="FD723_13775"
     CDS             1389..2024
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006197448.1"
                     /locus_tag="FD723_RS13800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_13775"
                     /product="response regulator"
                     /protein_id="WP_179065842.1"
                     /transl_table=11
                     /translation="MASNKILVIDDTTVVRVKVREMLPPGNFEVLEAKDGVEGLNFILQ
                     EKLSLIMLDFLLPKMSGWEVFQKVQADPELRKIPLVIMSGRKEEVTEKITEPFEYFEFL
                     GKPFDQKQLISAIKLAMTKAKQPRPELVAVGAAAAVKNGTVATLEVATATVAAPSIANV
                     AVVTPSSGGVSDVEINALNEKIAKMQAEIDGLKKQLTQVVTFIKQKIK"
     gene            2514..8189
                     /locus_tag="FD723_RS13805"
                     /old_locus_tag="FD723_13780"
     CDS             2514..8189
                     /EC_number="2.7.11.1"
                     /EC_number="2.7.13.3"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015137196.1"
                     /locus_tag="FD723_RS13805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_13780"
                     /product="ATP-binding sensor histidine kinase"
                     /protein_id="WP_179065843.1"
                     /sec_met_domain="Pkinase (E-value: 1.8e-37, bitscore:
                     127.6, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVLLDTLYSFPGYRITEQIYSGSKTLVYRGIREEDKKSVVLKLM
                     RNEYPTFAEIAQFRNQYIITKNLDIPGIVKTYSLENYRNSYVLVMEDFGGIPLQDWRLE
                     DKGKKENWLSLNEFFPIAIKIASTLERLHRDRIIHKDIKPANILINPTTDEIKLIDFSI
                     ATLLPREVQFLTNTNILEGTLAYISPEQTGRMNRGIDYRTDFYSLGVTFFQLLTGQLPF
                     TSKDPTELVYSHIAKQPLKASRVNSNIPPILSEIISKLMAKNAEDRYQSALGLKHDLEV
                     CQSQWQETGNIAPFELGVRDISDRFVIPEKLYGRQSEVETLLAAFKRVTTGATEMILVA
                     GFSGIGKTAVVNEVHKPIVRQRSYFIKGKFDQFQRDIPLSGLVQAFRDLIEQLLSESDT
                     QIQQWKAKILRELGTQTQVIIDVIPELEQIIGKQPPVRELSGSATQNRFNLLFQKFIQI
                     FTGKERPLVIFLDDLQWADTASLKLIQLLMCGSTLSSLSEETEQLDENQGGLLLIGSYR
                     DNEVSKAHPLYLTLQEIEQAAVNINTITLAPLNQGDLNHLIADTLHCPEVAAVPLTQMV
                     FAKTKGNPFFSVQFLKALQDDGLIFLNLDVSHWQYDILKVKELALTGDVVEFIALQIEK
                     LPIQTQKVLKFAACIGNQFDLKTLAIVNEKSVVDTASDLWQALLDGLVLPQTENYNIFS
                     KDDANEFITHGIESTQFSISNLQLPKYKFVHDRVQQAAYSLIPEEQKKPIHLKIGLLLL
                     NNIPVTEKEEKIFELVNQFNIAVEFISPQAKRDELAQMNLIAGRKALASTAYPAAVKYL
                     TTGIQLLADNSWEMKYELILALYETAAEAAYLDGDFEQTEQLAEIVLLQGKTLVDKVKA
                     YEVKIKASGAQNQALKGINTALAFLQLLGVEFPEHPSQSDVQLVMAEIASNLAGRDIED
                     LINLPEMTEAKTLAVMNILSSIHSLTYQAIPELFPLIIVKQINLSLQYGNAPLSAFAYV
                     NYGIILCALVGDIESGYKFGKLAVNLLSRLQIKEISAKVLGSFLSLLRPCKEHAKEILK
                     PLLQAYSIGIETGDLEYAAYSLHIYSYCSYFIGRELSELEQEMANYNNAIRQLKQKTVF
                     QWSNIYRQSVLNLLGCAENSYYLIGEVYNEDKMLPIHLETKDGLGLLYLYVKKLHLCYL
                     FQEFHQAVENATLAKKYLDTAIGHLVVPVFHFYDSLAGLAVYFEVSESEQKSILDRVQA
                     NQEKMDHWAHHAPMNYLHKYYLVEAERYRIGGQYLEAMEFYDRAIFLAKENEYVNEEAL
                     AQELTAKFYLEWGKHKIAQTYLTDAYYSYVRWGALAKVDDLAKRYPQLLAPIFQQEKLS
                     IHSSEESTSFYNTSISSLSTLSNQQTVIASKTSISDSLDLAAFIKASQALSSEIELERL
                     LSTLMEVVMENAGASKCALILSEGDNLALTVTTVCSSSNFDHTYTEFPSISLESSYDVP
                     ITLINYVKRSREILVIDDATTVSFLAGDSYILSEEPKSLLAIPLLNQGKLIGIIYLENN
                     LTTGAFTRDRVEVLKLLTTQAAISLENAILYKNLAQAKESLEEYNHTLEEKVQERTQEL
                     NDKNYSLQQTLQELQRTQIQLIQSEKMSSLGQMVAGVAHEINNPINFIHGNINHASEYV
                     KDLLDLVVLYQQEYPHPSPLVEEKSEEIDIDFLTEDLLKILDSMKIGSSRIRNIVLSLR
                     NFSRLDESEMKPVDIHEGIDSTLMILQHRIQEKHNLTEIQVIKEYGKLPEIMCYPGQLN
                     QVFMNILSNAIDALEESFVIGDPSLVNNKEQITKDIEASAVFDMVGQIHIFTERTDSNT
                     AIIRIADNGSGMTKAVQQKIFDPFFTTKSVGSGTGLGLSISYQIIVDKHRGSLTCDSTL
                     GKGTEFVIEIPMQQPDI"
     gene            complement(8464..9852)
                     /locus_tag="FD723_RS13810"
                     /old_locus_tag="FD723_13785"
     CDS             complement(8464..9852)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012410186.1"
                     /locus_tag="FD723_RS13810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_13785"
                     /product="cytochrome P450"
                     /protein_id="WP_179065844.1"
                     /sec_met_domain="p450 (E-value: 1.2e-75, bitscore: 253.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLPNPLKTPSLLQKLQWITDPVSYMENAAQQYPDIFTGRIIAFG
                     DTVVFVNHPQGIQEILTNDRKKFVAAGELNKITEPWLGKNSVLILDGSRHKQQRQLIMP
                     SFHGERMQSYGQQIRNITENAFSQLLLNQPFLARNITQEISLQVMLQIVLGLYGGERFQ
                     KLKHSLPLLLNLSHSPITSSFFLLPFLQQDLGAWSPWGKFLRDRETTDQLFYAEIAERR
                     QQPNSECVDILSLLILAQDETGQFMTDHELRDQLMTLIIGAYETTASVIASGLYWIHQK
                     PLVREKLLQEVDTLGDSPDPMSIYRLPYLTAVCNEILRVSPVLPFCFPRVVQEPVKLLG
                     HSLEPGTVLLPSIYLTHQREDLYPQPKEFRPERFLERQFSPYEFLPFGGGVRRCIGEAL
                     GLFQMKLVLATILSRYQLAVVNQQPERPQRRGFTLASASGVKMVITGRRREAQEPLVNK
                     LIGI"
     gene            complement(10001..10966)
                     /locus_tag="FD723_RS13815"
                     /old_locus_tag="FD723_13790"
     CDS             complement(10001..10966)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012410187.1"
                     /locus_tag="FD723_RS13815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_13790"
                     /product="terpene synthase family protein"
                     /protein_id="WP_179065845.1"
                     /sec_met_domain="T1TS (E-value: 2.8e-82, bitscore: 276.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQLAYPDLYCPFPSHINKHIDVLERHALEWVLRFNLLANKSSYQ
                     RFCKSKFFFLAASAYPNCQLEELKIANDWLSWAFIWDDQCDLSNLGRQPDILKDFHKRF
                     LEILNGAELTSKDIPLAYALSDLRQRILQRGSQEWFHYFVARYEGYFDGCVQEAVNRAQ
                     EITPDVDSYMLIRRLTLGGYVFLALMEFCNYLIIPDSLRNHEVMKELKAMTINILAWCN
                     DIFSVHREMSSGDVHNLALLIYYQQNISLEQAIFIVSEMHDQEVHRLKEFESSLPSFGE
                     ELDAELAKYISGLHSWISANLNWYSHSGRYQTIDSLELNQ"
     misc_feature    11277..11288
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.48"
                     /tool="antismash"
     gene            11625..12944
                     /locus_tag="FD723_RS13820"
                     /old_locus_tag="FD723_13795"
     CDS             11625..12944
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015121475.1"
                     /locus_tag="FD723_RS13820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_13795"
                     /product="response regulator"
                     /protein_id="WP_179065846.1"
                     /transl_table=11
                     /translation="MNEKPDMKILDEPEDNLILVVDDTTTNLEIVFNILTNFGFKVITE
                     HDGKRAIQIVEDTLPDLILLDVMMPRIDGFETCKMLKENSATCDIPVIFMTANSDTDSK
                     VKGLNIGAVDYITKPFHEEELLARIKTHLQLRNLTKTLEKRVVERTAALSRALKDLQES
                     QLQLVQTEKMSALGQLVAGVAHEINNPVGFIHGNLGHASVYFQDMVNLIDLYQKHYPNP
                     VLEIQEEITAIDLQYMLSDLPNLISSMKEGVQRIRNISTSLRTFSRADSDRKVSCNIHD
                     GIDSTIMILKHRLKASEDRPDIQVIKDYDKLPDLECFIGQLNQVFMNLLANAIDALEES
                     NIGRTYLDIEADPNQVFIQTLLTEDKNHILIRIKDNGVGMSADIQQKIFDHLFTTKPVG
                     QGTGLGLSIARQIVVEKHGGTLEVNSVLGKGSEFIIRLPI"
     gene            12987..14138
                     /locus_tag="FD723_RS13825"
                     /old_locus_tag="FD723_13800"
     CDS             12987..14138
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012410189.1"
                     /locus_tag="FD723_RS13825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_13800"
                     /product="FIST signal transduction protein"
                     /protein_id="WP_179065847.1"
                     /transl_table=11
                     /translation="MFKAVVGHSNDPDSLSAVEEVILQCASSLAGDIPKAGIIFAAIDF
                     EHALILQQIHQAFPGIELIGGTTDGEISSVLEFQQDSITLMLFCSDEVEIHAGIGRKVS
                     SDPITATQQAVEQAKAKSTAPPKLCLTHPESLTTSGISILNGLKLALGEYIPIFGGLAG
                     DQSRYQSTYQFFQTEVLSDSVPILLFSGTILFSHAVASGWHPIGQTSKATKVDKNIVYE
                     IDGKPALDFYHHYLGSLPPSMEYPLAVFDQNGDNFYIRAPIAYNQESGSITFFGDIPDQ
                     AVIQISEADHEDILAASKASFMNALDNYPGAKPSAVLFFSCVARRQILGTRAQEEYQNT
                     KLCLTDYLPACGFYSYGEIAPIDRTIQTQFHNETFVTLIVGTR"
     gene            14145..15188
                     /locus_tag="FD723_RS13830"
                     /old_locus_tag="FD723_13805"
     CDS             14145..15188
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015130895.1"
                     /locus_tag="FD723_RS13830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_13805"
                     /product="sensor histidine kinase"
                     /protein_id="WP_179065848.1"
                     /transl_table=11
                     /translation="MEILDYQQEIRELKKANRIIQKKLERSESDRIKLEDTNKKKEFLL
                     KKVIDELNEYQYKLEERGHELETMLLNLQIMQNKMSTLGSLVADVAHEINNPVGFIAGN
                     LTPAKEYIQNLLHLINLYQQTYPKASQEIEETIQLIDLEYVRDDLPKLISSMREGTDRI
                     SNISNSLRTFSRADTEQKVLFNIHEGINSTLMILKHRLKANKIRPAIELVQDYEELPLV
                     ECFPGQLNQVFMNLLANAIDALEESNYGLSFDEIKLNPNQITIHTALTEDNNHVSIRIQ
                     DNGVGISADVQQKIFDHLFTTKPVGKGTGLGLSIAYQIIVQKHKGTLEVNSVLGAGSEF
                     IITIPIF"
     misc_feature    complement(15628..15642)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.38"
                     /tool="antismash"
     gene            15718..16260
                     /locus_tag="FD723_RS13835"
                     /old_locus_tag="FD723_13810"
     CDS             15718..16260
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012410191.1"
                     /locus_tag="FD723_RS13835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_13810"
                     /product="methanogen output domain 1-containing protein"
                     /protein_id="WP_179065849.1"
                     /transl_table=11
                     /translation="MSNALDRSIATLNLSLERDIFLRTLIRELSGTLQDVVGLKEASGF
                     ISVVGERMGRQLDQDYKSALEVSSLSRKQVADVLIDLKKRIQGDFYVIEQNDEKIVFGN
                     RVCPFAEKVLNRPAMCMMTSNVFGTIAANNLGYAKVELQDTIAEGASGCRVIVYLKPTE
                     EAEDAEGREYFRGLESV"
     gene            16345..17736
                     /locus_tag="FD723_RS13840"
                     /old_locus_tag="FD723_13815"
     CDS             16345..17736
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012410192.1"
                     /locus_tag="FD723_RS13840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_13815"
                     /product="ATP-binding protein"
                     /protein_id="WP_179065850.1"
                     /transl_table=11
                     /translation="MTPEQFLELARVLPEPLLLVSGEGQLLATNQPVADMLGLRRQELR
                     GRMLFELVTESTNDVVKYLQACSSSREMVIGSLTLRKNDGQNLICRSQGAVIQPWSAES
                     SALILLRLENRVVASSNFVLLNEKIDELAKEVQRRKQAEEALKKANQELEVRVQERTTD
                     LQETLNELQLTQTQLIQAEKMSSLGQMVAGIAHEINNPVSFIYGNLHHAYKYTQDLLTL
                     VQIYQQICPNIPPEIEAKVEEIDLDFLIQDITKLFESMKVGTERIQEIVKSLRNFSRLD
                     EAEFKQVNIHEGIDSTLMILEHRLQARHEYPEIKVIKKYSQLPNVTCYPGQLNQVFMNI
                     LTNAIDSLELLANNGHWSAVNPQTTDNQQLADNNPKIQIKTELIDQKWIEVTIADNGLG
                     INEQVLSKLFDPFFTTKSVGKGTGLGLYISYQIIVEKHKGQLNCFSVPGKGAEFVIKIP
                     VSSVS"
     gene            complement(17907..19511)
                     /locus_tag="FD723_RS13845"
                     /old_locus_tag="FD723_13820"
     CDS             complement(17907..19511)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012410193.1"
                     /locus_tag="FD723_RS13845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_13820"
                     /product="NAD(P)H-quinone oxidoreductase subunit N"
                     /protein_id="WP_179065851.1"
                     /transl_table=11
                     /translation="MDFANIASQLNAGTILPEGIVILTLLGVLIVDLILGRTSARWIAY
                     LAIAGLFASIVALYFQWDSPNPIGFTGSFNSDDLSIVFRGIIALSAIATILMSIRYVEQ
                     SGTALAEFIAILLSATLGGMFLSGASELVMIFISLETLSISSYLLTGYTKRDPRSNEAA
                     LKYLLIGASSTAIFLYGVSLLYGLSGGQTELSAIANGIATAKVGQSLGLVIALVFAIAG
                     IGFKISAAPFHQWTPDVYEGAPTPVIAFLSVGSKAAGFALAIRLLTTAFPLVADEWRFV
                     FTALAVLSMILGNVVALAQTSMKRMLAYSSIAQAGFVMIGLIAGTQAGYASMVFYLLVY
                     LFMNLCGFTCIILFSLRTGTDQIAEYSGLYQKDPLLTLALSISLLSLGGIPPLAGFFGK
                     IYLFWAGWQAGLYWLVLLGLVTSVVSIYYYIRVVKMMVVKEPHEMSDAVKNYPQVRWDL
                     PGLRPLQVGLVVTLIATTVAGILSNPLFTLANNSISNTPFLQATINSNVKAQNLVLLPK
                     LDSVNQSQPSVDSTAKI"
     misc_feature    19462..19476
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.17"
                     /tool="antismash"
     misc_feature    complement(19594..19611)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.54"
                     /tool="antismash"
     gene            complement(19950..20222)
                     /locus_tag="FD723_RS13850"
                     /old_locus_tag="FD723_13825"
     CDS             complement(19950..20222)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012410194.1"
                     /locus_tag="FD723_RS13850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_13825"
                     /product="hypothetical protein"
                     /protein_id="WP_179065852.1"
                     /transl_table=11
                     /translation="MNIVKLILLAFPAFLVSMLLIVNPANASSLKSTYATQMMTVVSTQ
                     QITDLATPNLIQTSNPIIDQLGCNCANCVQSKFQSLQGKLPSVGF"
ORIGIN
        1 tgtcggcaac tggggaaatc ttagttttag cagtcataat tcaattctcc taatgtcagg
       61 actttttaag aaataccaaa ctggcgtacc aaatactcaa attctttaag aatatttgtg
      121 tgaagttggg aattgggaag aggcagaggg gcagggagca gggagaagag gggaaagagg
      181 ggaaagaggt aattatttta ttctccccct taacccctgc cccctgcccc ctgctcccct
      241 gcttcccctg ctccctcttc tccagcatga taggaactgc gaaccagagg cccagaacga
      301 acatggttga atcccatttc ccatgctaat ctgccgagtt gatcgaattc ctctggagtc
      361 caatattttt ggactggcaa atgttctagg gaaggacgca tatactgacc aatagtcaag
      421 cgatcgcacc cgacagccct taaatcagtc attgcttcaa tgacttcatc aagtgtttct
      481 ccgtgtccca gcatcaaacc tgatttggtg ggaatggtcg aatcaatttc tttgaccata
      541 gccagcacta acagggagcg atcgtacttg gctccccggc gcactggccc tgttaaccgc
      601 cgcactgtct caatattgtg attgaaacaa gctggtttgg ctttcacaat catctctatc
      661 cgctgacgtt gacctgattc cccaatacca gcaccacccc aaaaatctgg ggtcagcact
      721 tcaatttgag tctctgggtt caattggcgg atagtcgcga tcgtcttcac aaaatgccct
      781 gcaccctgat cgggcaagtc atcacgggct acagaagtca gcaccacata acgcaatccc
      841 aaaagctgca ccgcctgggc gaccttttca ggttcctcta aatcaagagg cattggtgca
      901 tgacctttat ctacttgaca gaaagcacaa gagcgtgtgc aggtaggccc cattagcaag
      961 aaagttgcag ttttttgggc gtagcactct ccacggttag ggcagcgtcc ttcttcacaa
     1021 atcgtgtgaa tttggcgctg cttaataatg cgttgtacgg tagagatttc actggctttg
     1081 ccaatcgagc gacgtaacca gctaggcatt gccgtaattt cagactttag ttcggcttgt
     1141 tgtgacgcaa tcatagacat ctaagcaaga tgcggatata gatgtagtgg tctatcggtt
     1201 aaatatcacc atgacacaaa ttgaaaagag cgcgagcaaa agttttgcaa aacacccctc
     1261 acaatgtcat ttataccgaa atatactatc ccccaattgc tagaaatttt gtatatagtg
     1321 ggaggattct caagggcaat cggcaaagcc gctatttaca cttatagttt ctgttagagc
     1381 aaacagtcgt ggcaagcaac aagattttag ttatcgatga cactacagtt gtcagggtaa
     1441 aagtacgaga aatgttgcct ccgggcaatt ttgaggtact ggaagcaaaa gacggtgtgg
     1501 aaggattaaa tttcattctt caggaaaaac tcagcctaat tatgctggat ttcctgttgc
     1561 ctaaaatgag tggttgggag gtttttcaga aagttcaagc cgatccggag ttaaggaaaa
     1621 ttcctttggt gatcatgtct ggtcgcaagg aagaggtgac tgaaaaaatc acagaaccct
     1681 ttgaatactt tgaatttctg ggcaaacctt ttgatcaaaa gcaactaatt agcgcaatta
     1741 agttagctat gaccaaggcg aaacagccac gcccagaact agtagcagtg ggagcagctg
     1801 cggccgttaa aaatggcaca gttgcaacac tagaggttgc aactgctaca gtagcagccc
     1861 ctagcatcgc caatgttgca gtagtaaccc ctagttctgg aggagtctcc gacgtagaaa
     1921 ttaatgcgtt gaacgagaaa attgccaaaa tgcaggcaga aattgatggt ttgaaaaaac
     1981 agctaactca ggttgtgact tttattaaac aaaaaatcaa gtagtatttg cgctcgttat
     2041 tattatcgca gctaaaaata caccgtctct aataacaggt gtccgattca aagcgggtaa
     2101 aaatagttag ttcaaaaata cttatgttga tgttgataag tcataattat ctactgagat
     2161 ccagtttaac ctcaccccga taaagctatg ctttatctcc cctttgctca caaagaggga
     2221 ttggggtgag atttttatat gtatttaact caatacagtt cagaatgagc aacaaaacac
     2281 ttgtagagac ggcgatttat cgcgtctcga aagcccaaaa ttgttgccag tagcccttaa
     2341 cccaagcgta ttggtattta aatagataag gaaacgcttt taagatttaa atatttagta
     2401 aaaaattata tttcctaata caaattaaac aaaaaaatcc tatttcatga tgaggatagt
     2461 cttcgcacgg gaataataag ccatagaaac aataattatg tgcatagtcc gcaatgttag
     2521 tactattaga tacattatat tcctttcctg gctatcgaat taccgagcaa atctactcag
     2581 gcagtaaaac cttagtttat cggggcatca gagaagaaga taaaaaatca gtcgttctca
     2641 aattgatgcg gaatgaatat cctacctttg cggaaatcgc ccaattccga aatcaatata
     2701 tcatcaccaa aaaccttgat attcctggca tagtcaaaac ctatagttta gaaaactacc
     2761 gtaacagcta cgtcttagtg atggaagatt ttggcggcat tcccctccaa gactggcgac
     2821 tggaggacaa ggggaagaag gaaaactggc tttctctcaa cgagtttttc cccattgcga
     2881 ttaaaattgc ttctaccctt gaaagactac atcgcgatcg cattattcac aaagacatca
     2941 agcctgccaa catcctcata aaccctacca cagatgaaat aaaactcatc gactttagta
     3001 ttgccaccct cctaccaaga gaagttcaat ttctcaccaa taccaacatc ttagaaggca
     3061 ctctggctta tatttcccca gaacaaaccg gcagaatgaa cagaggtatc gactaccgta
     3121 ctgattttta ttcccttggt gtcaccttct ttcaactcct caccggacag ttacccttca
     3181 ccagcaaaga tccaacggag ttagtttact ctcacattgc caaacaaccc ctaaaagcca
     3241 gtcgggttaa ctctaatatt ccgccaattt tgtctgagat catcagcaag ctgatggcaa
     3301 aaaatgccga agaccgctat cagagtgctt tgggattaaa gcatgactta gaggtgtgcc
     3361 aaagccagtg gcaagaaaca ggaaatattg caccctttga actaggcgtg agagacatct
     3421 cagatcgttt cgtaatcccc gaaaaactct acggtcgcca aagtgaagtt gaaaccctac
     3481 ttgcggcttt taagcgcgta acaactgggg ctacagaaat gatattagtt gcgggtttct
     3541 ctggcattgg caaaactgct gtggtcaatg aagtccataa acctattgtg cggcagcgta
     3601 gttacttcat caaaggaaaa tttgaccagt ttcaacgcga tattccctta tcaggattgg
     3661 tacaagcttt tcgggactta atcgagcaac tcctctcaga aagtgatacc caaattcaac
     3721 aatggaaagc caaaattctg cgagaattgg gtacacaaac tcaggtgatt attgatgtaa
     3781 ttcctgaact tgaacagatt attggcaagc agcctccagt tagagaactc tctggcagtg
     3841 ctactcaaaa tcgattcaat ttattgtttc aaaaattcat ccaaatcttc acagggaaag
     3901 aacgccctct agttatcttt ctcgatgact tgcaatgggc agatacagct tctctaaaat
     3961 taatccagtt attaatgtgt ggaagtacgt tgtcttctct atcggaagag acagaacaat
     4021 tggatgaaaa tcagggtggt ttattgttaa ttggttccta tcgagacaat gaagtttcca
     4081 aggcacatcc gctttattta acattacagg agattgaaca agcagcagta aatattaata
     4141 caattaccct agcaccttta aatcagggtg atttaaatca tctcattgct gatacccttc
     4201 attgtcctga agtcgctgcg gttcctctca cccagatggt gtttgccaaa actaaaggta
     4261 accccttctt ttctgttcaa tttctcaaag ctttacagga tgatgggcta attttcttaa
     4321 atcttgatgt tagtcattgg cagtatgata ttttaaaagt caaagaatta gctctcacag
     4381 gtgatgtcgt agaatttatc gctctgcaaa tagaaaaatt gccaatacag acccaaaaag
     4441 ttctaaaatt tgctgcctgt attggtaatc aatttgactt aaaaactcta gcgatcgtca
     4501 atgaaaaatc tgtagtagat acagcatcag acttgtggca agcattactt gatggattag
     4561 ttttaccaca gactgaaaat tacaacatat tttcaaaaga tgatgctaat gaatttatta
     4621 ctcatggaat agaatctaca caattttcaa tttctaattt acagctacct aaatataaat
     4681 tcgtacatga ccgggtgcag caagctgctt attctttaat tcctgaagaa caaaaaaagc
     4741 caattcactt aaaaattgga ctactgttat tgaacaatat tccagttacc gaaaaggaag
     4801 aaaagatttt tgagcttgtc aatcagttta atattgcagt ggaatttatc tcccctcaag
     4861 ctaaacgaga tgaactagcc cagatgaatc tgattgctgg acgtaaagcc ttagcatcaa
     4921 cagcttatcc cgctgctgtt aagtatttaa ctactggtat tcaattgcta gcagataata
     4981 gttgggagat gaaatatgag ctaatcctag ctttgtatga gacagcggca gaggccgcgt
     5041 acttggacgg cgactttgag caaaccgagc aattagcaga gatagtgttg ctacaaggga
     5101 aaactcttgt agataaagtt aaagcttacg aggtaaaaat taaagcatct ggggcacaga
     5161 accaagcact caaaggaatt aatactgcac tagccttttt gcagcttttg ggagtagagt
     5221 ttcctgaaca tccaagccaa tctgatgttc aactagtaat ggcagaaata gcatcaaatc
     5281 tggctggtag ggatattgaa gatttaatta acctgccaga aatgacagaa gctaaaacac
     5341 tagcagttat gaatatttta tcgagtattc atagtttgac ctatcaagct attcctgaat
     5401 tattcccact gattattgtt aaacaaatca acttatctct acaatatggt aacgcaccat
     5461 tgtctgcctt tgcctatgtt aattatggaa taatactgtg tgcgctagtg ggagatattg
     5521 agtccggtta taaatttggt aaactagctg taaatctttt atctaggtta caaattaaag
     5581 aaattagcgc gaaagttctt ggatcttttc tttcacttct tagaccttgt aaggaacacg
     5641 ccaaggaaat attaaaacct ttgttgcaag cttattctat cggtattgaa acaggagatt
     5701 tagagtatgc agcttattct ctacacattt attcttactg ctcatatttt atcggtagag
     5761 aactttcaga gttagaacaa gaaatggcaa attataataa tgccatcaga caactcaagc
     5821 aaaaaacagt attccaatgg agtaatattt atcggcagag cgtattgaat ctactagggt
     5881 gtgcagaaaa ttcctattat ttaattggtg aggtttataa cgaagataaa atgctgccga
     5941 tccatttgga aactaaagat ggacttggac tcctatatct ctatgtcaaa aaacttcatc
     6001 tctgttatct atttcaagaa tttcatcagg cagttgaaaa tgccacacta gcgaaaaagt
     6061 atttagatac tgcaatagga catctagttg ttccagtttt ccatttttat gattctttag
     6121 caggtttagc tgtgtatttt gaggtatccg aatctgagca aaaatctatt ctcgatcggg
     6181 ttcaagccaa tcaagaaaaa atggatcatt gggcacatca tgccccaatg aattatttac
     6241 acaaatatta tcttgtagag gctgaacgct atcggattgg tggtcaatat cttgaagcaa
     6301 tggaatttta cgatcgcgcc atcttccttg ccaaagaaaa tgagtatgtt aatgaagaag
     6361 ccctcgctca agaacttacc gccaagtttt atttagaatg gggtaaacat aagattgccc
     6421 aaacctatct aacagatgct tactatagct atgttcgctg gggagcgtta gccaaagttg
     6481 acgatttggc aaaacgctat ccccaattac tggctcctat atttcagcaa gaaaaactga
     6541 gtatccattc cagcgaggaa agcacttctt tctacaacac atccatatca tctttatcta
     6601 ccctgagtaa tcaacaaact gttattgcct cgaagacaag tatttctgat tctctggatt
     6661 tagccgcatt cattaaagca tctcaagcac tctctagcga aatcgagctt gagcgactac
     6721 tttcgacttt gatggaagtt gtgatggaga atgcaggagc ttctaaatgc gctttaattt
     6781 taagtgaagg tgataactta gcattaactg ttacaacggt ttgttcaagt tcaaattttg
     6841 accataccta cacagagttt ccatcaattt ctttggagtc aagttatgat gttcccatta
     6901 ctttgattaa ctacgttaaa cgctccagag aaattttggt gattgatgat gcaacgactg
     6961 tttccttttt agcaggtgat agctatattc tgagtgaaga acctaagagt ttgttggcta
     7021 tacctcttct aaatcaaggt aaattgattg ggattattta tctagaaaat aatttgacga
     7081 caggagcatt tacacgcgat cgcgtagaag tactcaaact cctcaccact caagcagcaa
     7141 tatccctaga gaatgctatc ctctacaaaa atttggcaca agctaaagaa agtttggaag
     7201 aatacaacca tactctagaa gagaaagtcc aggagagaac gcaggaactc aacgataaaa
     7261 attactctct acaacaaact ctacaagaat tacaacgtac ccaaatccaa ttgattcaaa
     7321 gtgaaaaaat gtcttctttg ggacaaatgg tagcaggagt tgcccatgaa atcaataacc
     7381 ctattaactt tattcatggc aatattaatc atgctagtga gtatgtcaaa gacttgctgg
     7441 atttggtagt tctttatcag caagaatatc ctcatccttc gcctttagtt gaggaaaaat
     7501 ctgaggaaat tgatatagat ttcctcacag aagacttact aaagattcta gattcaatga
     7561 aaattgggag ttcgcgtatc cgcaatattg ttttgagctt acgcaatttt tctcgtctag
     7621 atgaatctga gatgaagcct gtagatattc atgagggaat agacagtacc ttaatgattt
     7681 tacaacaccg aattcaagaa aaacacaatc ttactgaaat tcaagtcatc aaagaatacg
     7741 gaaaattacc ggagattatg tgttaccctg gtcaactaaa tcaggttttc atgaatatcc
     7801 tgagtaatgc gattgatgct ttagaagagt catttgtcat tggtgatcca tcactggtaa
     7861 ataataaaga acaaatcaca aaggacatag aagcatcagc agtttttgat atggtaggac
     7921 aaattcacat ctttactgaa cgaacagatt ctaatacagc gataattcgg attgccgata
     7981 atggttctgg tatgacaaaa gcggtgcagc aaaaaatatt tgacccattt tttactacca
     8041 agtcggtagg aagtggtacg gggttagggt tgtcaatcag ctatcagatt attgtggaca
     8101 aacacagggg tagtttaacc tgtgattcca cattaggaaa ggggactgag ttcgtgattg
     8161 agataccgat gcaacaacca gatatctaga ctatggcaca atacagttca gataagacca
     8221 aaacacttgt agagacggct atttatcgcg tcttaaaaac ccacaatttt gtacaattag
     8281 cccttagctg aaccgtattg gactatggca accttatttg tccgccctga ttatgtaagg
     8341 gacttccaaa aaaaaatatc caattacttc ttgtggggtg cgtgtttcgc ccgccctatg
     8401 gactgggcgc tcatgttgcc caccccacaa tattggataa tttatttctt ggagttccct
     8461 aacttaaatg ccgatgagtt tattcactaa aggctcttga gcctcacgtc gtcgtcctgt
     8521 aattaccatc ttgactccac ttgcagatgc cagggtaaaa cctcgacgct gaggccgctc
     8581 aggttgctga ttaactactg ctaactgata gcgtgataag atggttgcca gtactaattt
     8641 catttgaaac aaacccaaag cctcaccaat acaacgacgg acaccaccac caaaaggcag
     8701 aaattcataa ggagaaaatt gacgttctag aaaacgttct ggtcgaaact ccttaggttg
     8761 gggatataag tcttcacgtt gatgagtaag ataaatacta ggaagcaata ctgttccagg
     8821 ctctaaagaa tgtcccaaga gtttaacggg ttcttgtact acccttggga aacagaacgg
     8881 taaaacaggg ctaactcgca agatttcatt acagacagcc gtaagatatg gtagtcgata
     8941 aatgctcata gggtctgggg aatcaccgag agtgtccact tcttggagca gtttttcacg
     9001 gactagaggc ttttggtgaa tccaatacaa tcccgaagct attacagatg ccgtagtttc
     9061 ataagcgcca attattaggg tcattagctg atcgcgcaat tcatgatctg tcataaattg
     9121 accagtttca tcttgagcta agatcagcaa ggaaaggata tcgacacatt ctgaattagg
     9181 ttgttgtcgg cgttcagcaa tttcggcgta gaacaattga tcggttgtct cgcgatcgcg
     9241 cagaaatttt ccccaaggac tccaagctcc taaatcctgt tgcaagaatg ggagcaagaa
     9301 aaaactagaa gtgataggtg aatgagagag atttaacagc aatggtagtg aatgcttaag
     9361 tttttgaaat ctttctcccc catacaaccc taagacaatc tgtaacataa cttgtagaga
     9421 tatttcttgt gttatattac gagccaaaaa gggctgattt agtagtaact gactaaaggc
     9481 attttcggta atattacgga tttgttggcc atagctttgc attcgctctc catgaaaaga
     9541 aggcattatc aattgtcgtt gttgtttatg acgactgcca tcaagtatga gaactgaatt
     9601 ttttcctagc cagggttcag taattttatt gagttcaccg gcagcgacaa atttctttct
     9661 atcattcgtt aaaatttctt ggattccctg aggatgattt acaaatacta cagtatcgcc
     9721 aaaggcaatt atcctaccag taaaaatgtc gggatattgt tgagctgcgt tttccatgta
     9781 gctcacaggg tcagtaatcc actgaagctt ttgtagcaaa gaaggggttt tgagaggatt
     9841 aggtagttgc atatgaattt tcagttcaaa ccaaaatcga aaaattgtat tagcgaggat
     9901 aaacccttaa caaaataata tgggttcatc tataatgagc tttcagcaaa ataggatacc
     9961 taacaggtat cctattccct tataaagata gagtgagaat ttattgattt aactccaagc
    10021 tgtctatagt ttgatagcga ccagagtgag aataccaatt cagattggca gatatccagc
    10081 tatgtagtcc tgatatatat ttggcaagtt ctgcatctaa ttcctctcca aaagatggaa
    10141 gagatgattc aaactctttc aagcgatgta cttcttgatc gtgcatttcg ctaactatga
    10201 aaattgcttg ttctaaagaa atattttgtt gataataaat taacaatgct aaattatgaa
    10261 catcgccact tgacatttct ctatgtacgg agaaaatatc attacaccaa gcaagaatat
    10321 taattgtcat cgcttttaat tctttcatca cctcatgatt tcggagagaa tcaggaatta
    10381 ttaaataatt gcaaaattcc atcaatgcaa ggaaaacata tccacctaaa gttaacctac
    10441 gtataagcat ataactgtca acatcgggtg taatttcctg tgcgcggtta actgcttctt
    10501 gaacacagcc atcgaaatag ccttcatagc gagcaacaaa gtaatgaaac cattcttgac
    10561 tacctctttg aagtatccgt tgtcgtaaat cacttaatgc ataagcaagt ggtatatcct
    10621 tactcgtgag ttctgcaccg ttcaatattt ccaaaaatct cttatgaaaa tctttgagaa
    10681 tatcaggttg tcttcctaaa tttgataaat cacactggtc atcccaaata aacgcccaac
    10741 tcaaccaatc atttgcaatt ttcaattctt caagctggca gttgggatag gcacttgccg
    10801 ctaggaagaa aaattttgat ttgcaaaaac gctgataaga tgatttattg gccagtagat
    10861 tgaagcgaag tacccattca agagcgtgcc tttctagaac atcaatatgt ttattgatgt
    10921 gggatggaaa tgggcagtat aaatcagggt aagctaattg attcataaaa aatgaattag
    10981 tttaaagtac caaaaaaatc atcacagtag aacaaagata attgctcaat atactgttag
    11041 aagtctttga gaaaactttt gcaaaaattc acatcgatcc catatttcta aagtgtgtaa
    11101 gttatattta cgccaccatt agtactatgt aagtctatat gaacttttaa aacctatctc
    11161 aacattgtta aatatttctt attaaaaaat aaccgtaatt atctggaatt atatttcttt
    11221 aataaaaata gctatctctg tgtatattcg ttcatgataa atgctgttga ctaactgaaa
    11281 aagttaactt atgagagcaa aaatattatt tcaagtagcg ctctttttgt aaaaagacaa
    11341 gggtaataat gactaatttc agagcgttct ctttcatgaa agagaatctt aaactccggc
    11401 gaaagtaaag attggtgctg aatgtccata ctgtagcgat caccccagct ataagctatg
    11461 ggcaatttag tgtgagaatg ttgctgttgt cagaattttt gggaactata agattgtcag
    11521 actagaaaat tgttagttag tccgacaata aaatagaggt gacttagctg cgatcgccag
    11581 acgaatagtg aataactaac aaggagttaa atcaatttaa atacatgaat gaaaagccag
    11641 atatgaaaat acttgatgaa ccagaagata atttaatttt agtagttgat gatactacta
    11701 caaatttaga aattgtcttt aatatattaa ctaattttgg ctttaaagta attacagaac
    11761 atgatggtaa gagggcaatt caaattgttg aagatacact acctgaccta attttgttag
    11821 atgtaatgat gccacgaata gatggatttg aaacatgtaa aatgctgaaa gaaaattcag
    11881 ctacttgtga tatacctgta atttttatga cggctaattc tgatactgat agtaaggtca
    11941 agggtctaaa tatcggggca gttgactaca ttactaaacc ttttcatgaa gaagaattat
    12001 tagctagaat taaaacccat cttcaattac gaaatctcac aaaaacttta gaaaaacgag
    12061 ttgtagaaag aacagcagcc ttatccaggg cattaaaaga cctacaagag tctcaactcc
    12121 agcttgtaca gacagaaaaa atgtctgctc ttggtcaatt agtagcagga gttgcacatg
    12181 aaattaataa tccagttggt ttcattcatg gcaatctcgg acacgcttca gtatattttc
    12241 aagacatggt taacctgatt gatctctatc aaaagcacta tcctaatccg gttctagaaa
    12301 ttcaagagga aattacagca atagatttgc agtatatgct ttccgatcta ccgaatttaa
    12361 tttcttcaat gaaagagggt gttcagcgca ttcgcaacat tagtactagt ctgagaacct
    12421 tttctcgagc agatagcgat cgcaaagttt cttgcaacat tcatgatggc atagatagca
    12481 ctatcatgat tctcaaacac cgcttaaaag catccgagga tcgtcctgat attcaagtaa
    12541 ttaaagacta cgataaattg ccagacttag aatgctttat cggacaacta aatcaggtat
    12601 ttatgaattt gttagctaat gctattgatg ctttagagga atctaatata ggacgtactt
    12661 atcttgacat tgaagcagat cctaatcaag ttttcattca gactctactc actgaagata
    12721 aaaatcatat cttgattcgg attaaagata atggcgtggg aatgtcggct gatattcagc
    12781 aaaaaatctt tgaccattta tttactacca agcctgtggg tcaaggtaca ggattaggac
    12841 tgtcaattgc ccgtcaaatt gttgtcgaaa aacatggcgg aactctagag gtaaattcag
    12901 tactaggaaa aggttcagaa tttatcatca ggcttcccat ttaaaaatca gagcaaatcg
    12961 cgtttatcaa cataataagt aaatttatgt tcaaggcagt agtaggtcac agtaacgatc
    13021 cagattctct atcagcagtt gaagaagtta ttctgcaatg tgctagttct cttgcaggag
    13081 atataccaaa agctggaatt atttttgctg caattgactt tgaacatgct ctgattttgc
    13141 agcaaattca tcaagctttt cctggtattg agttgattgg tggaacaaca gatggagaaa
    13201 tttcttcagt cttagagttt cagcaggact caatcacctt gatgttgttt tgctcagatg
    13261 aagttgaaat acatgcagga attggacgaa aagtttcaag cgatccaatt actgcaactc
    13321 aacaagctgt ggagcaagct aaagcaaaaa gtaccgcacc cccaaagcta tgtttaactc
    13381 atccagagag cctcacaact agtggtatct ctatattaaa tggcttaaaa ctagctcttg
    13441 gtgaatatat accgatattt ggtggtttgg ctggcgatca gtcaagatac caaagtacat
    13501 atcaattttt tcaaacagaa gtattaagtg attctgtacc aattttactt ttttccggca
    13561 caatattgtt ttcccatgct gttgcaagtg gttggcatcc tattggtcaa acaagtaaag
    13621 ctactaaggt agataagaac atagtctatg aaatagatgg caaaccagct ttagattttt
    13681 atcatcatta tctaggttcg cttcctcctt caatggaata tccattagca gtgttcgatc
    13741 aaaatggaga caatttttat ataagagcgc ctattgctta taatcaagaa tctggtagca
    13801 tcaccttttt tggagatatt cccgatcaag cagttattca aatttcagaa gcagatcatg
    13861 aggatatttt ggcagcatcg aaggcgtcat tcatgaatgc tttagataat tatccaggtg
    13921 caaaaccaag tgctgttttg tttttttcat gtgtagctcg tcggcaaata cttggtacga
    13981 gggcacaaga agagtatcaa aacacaaaac tttgtctgac tgactattta cctgcctgtg
    14041 gattttattc ttatggagag attgctccta tagatcgaac tattcagacg caatttcata
    14101 atgaaacttt tgtaacttta attgttggaa ctaggtaaaa actgatggaa atattggatt
    14161 atcaacaaga aattagggaa ctaaaaaaag ccaatagaat tatccaaaaa aaattggagc
    14221 gttctgaatc agaccggata aaactcgaag atacaaataa aaaaaaagaa ttcttgctca
    14281 aaaaagtaat tgatgaatta aatgaatatc aatacaagct agaagaaaga ggccatgaac
    14341 tagaaacaat gcttcttaat cttcaaataa tgcaaaataa gatgtctact ttgggaagtc
    14401 ttgtcgcaga tgtagctcat gagattaata acccagttgg gtttatagca ggtaatctga
    14461 ctccagctaa agagtatatt cagaatttat tacatctcat taacctctat cagcaaacct
    14521 atcctaaagc atctcaggaa attgaagaaa caattcaatt aattgatctg gagtatgtgc
    14581 gcgacgatct acctaaactc atttcctcaa tgagagaagg cacggatcgt atttccaaca
    14641 ttagcaatag tctccgaact ttctctagag cagatacaga acaaaaagtt ctgtttaata
    14701 ttcatgaagg tattaatagc actctgatga ttctcaagca ccgtttgaaa gctaataaaa
    14761 ttcgtcctgc tattgaatta gttcaagatt acgaagaatt acccctagtt gaatgctttc
    14821 caggacaact aaatcaggta tttatgaatc tattggcaaa tgctattgat gctttagaag
    14881 agtctaatta tggactgagt tttgatgaga ttaagctaaa tcctaatcaa attactattc
    14941 atactgccct aactgaagat aacaatcatg tctcgattcg gattcaagat aatggggtgg
    15001 gaatatcagc tgatgttcaa caaaaaatat ttgaccattt attcacaact aaacctgtag
    15061 gaaaaggaac aggattagga ttatcaattg cttatcaaat aattgtccaa aaacataaag
    15121 gaactctaga agtgaattct gtgttaggag caggttctga atttataatc actattccaa
    15181 ttttttaaaa tagtaactat attaattatt aaaattaatt ttatgagaaa taaaaggctc
    15241 taatttacaa gcgtttcaag taaaaaagtc aggtgaccaa aaaatctgat tgggcaagaa
    15301 aatcgcgatg cctccagcaa ggcttcgcca acgcactgaa atttactcgt tgaggtggta
    15361 gcttttcgat gaccaaatta agcaagtttc tgactcatac tcttgacaaa atatctaaga
    15421 gatcgaatga aatagccctg cctcttggta agggggagaa ccggataatc cccccttatc
    15481 aaggagggat tatagtgggt aaatccaggc tttgggcttc attagcaaga tgtgtgtaca
    15541 ccgtagaggc taacgccaag agagaaggat gcaaagaaag agaagtttaa ctgaactgta
    15601 ttgtcttatg aacaaaagca agcatcaaat tctctgaata aagagattaa gcagttagtt
    15661 tagatgtatt tttgggaact ctataactgt agttccagga ttatttcctc aaaacttatg
    15721 agtaatgcac ttgaccgctc gatagctacc cttaatcttt ctttagaacg cgatatattt
    15781 ttacgtacat taattagaga attatctggc actttacagg atgtagttgg cttaaaagaa
    15841 gcttctggat ttattagcgt ggttggtgaa agaatgggta ggcaacttga ccaagattat
    15901 aaatctgccc tggaagtttc cagcctttct cgtaagcaag tggctgatgt cttgattgat
    15961 ttaaaaaaac gaatccaggg cgatttttat gtcattgagc agaatgatga aaaaattgtc
    16021 tttggcaacc gcgtctgccc atttgccgaa aaagtgctta atcgccctgc tatgtgtatg
    16081 atgacttcaa acgtctttgg gacgatcgca gctaataacc tgggatatgc gaaagtagaa
    16141 ttgcaagaca ccatagccga gggtgcttct ggatgtagag ttattgttta cttaaaacct
    16201 acagaagaag cagaagatgc agaaggtcga gaatactttc ggggactgga atctgtttaa
    16261 atccttaaat actaaaccaa ccccaggata taaacttgag tgcagatatc taaagtagag
    16321 ttcaaccctg aaattggaag ccccatgact cctgaacaat ttcttgaact tgccagagtt
    16381 ttaccagaac ctttactcct ggtaagtgga gagggtcagt tgttagctac caatcaacca
    16441 gtcgcagata tgttggggtt acgtcgtcaa gaactgcggg gaagaatgct ctttgagctt
    16501 gtaactgagt ctaccaacga tgttgtaaag tacctgcaag cctgttcaag tagcagggaa
    16561 atggtgattg gctctttgac tttacgaaaa aatgatggac aaaacttaat atgtcgtagt
    16621 caaggagcag tgattcaacc ttggtctgcg gaatcttcag ctttaattct cttacgcttg
    16681 gaaaatagag ttgtagctag cagtaatttt gttctgttga acgaaaaaat tgatgagtta
    16741 gcaaaggaag tacaaagacg taaacaggcg gaggaagcac ttaagaaagc taatcaagag
    16801 ctagaagttc gggttcagga acgcacaact gatttacaag aaacactaaa cgaactacaa
    16861 cttacccaaa ctcagctgat ccaagccgag aaaatgtcta gtttaggtca gatggtcgct
    16921 ggtattgccc atgaaattaa taaccccgtg agttttattt atgggaacct tcaccacgcc
    16981 tataaataca ctcaggattt actaacattg gtacaaattt atcaacaaat ttgtccaaat
    17041 attcctccag aaatcgaagc aaaagtagaa gaaatagact tagattttct gattcaagat
    17101 ataactaaac tcttcgagtc aatgaaggtg ggaacagaac gcattcaaga aattgttaaa
    17161 tcgctacgta acttttccag acttgatgaa gcagaattta agcaagttaa tattcacgaa
    17221 ggaattgata gtactttaat gattttagag catcgtctgc aagctaggca tgagtaccca
    17281 gaaatcaaag ttatcaaaaa atacagtcaa ttacccaatg taacttgcta ccctggtcaa
    17341 ctcaaccaag tgtttatgaa tattcttact aatgcaatcg attccctaga gttattggct
    17401 aataatggtc attggtcagc cgtaaatcca caaactactg acaatcaaca actcgcagat
    17461 aataatccta aaattcaaat aaaaactgag ttaatcgatc aaaagtggat agaggttact
    17521 attgctgata atggtttagg gataaatgaa caagttctct caaagctatt tgatcctttt
    17581 ttcaccacta aatctgtggg taaaggtact ggactagggc tatatataag ctatcagatt
    17641 atagttgaaa aacataaagg acaacttaac tgtttttctg ttccaggaaa aggtgcagaa
    17701 tttgtaatta agatacctgt tagctctgta tcataaaaat ataagaattc agcacccaaa
    17761 agtcagaaat tatcagtaat ttagaataat ttgtatattt attcatcaat tctgaattct
    17821 aactatttta aattgatatg aaaaacacct gtctgctaat tagcaaacag gtgtgtcttt
    17881 gagtacgaag cttggttgag actcggttaa atcttagcag tagaatcaac tgagggttga
    17941 gactgattaa ccgaatctaa ctttggcaaa agcactagat tttgtgcttt tacattactg
    18001 ttgattgttg cttgcaaaaa tggggtattt gagatggaat tgttagccaa tgtaaacagg
    18061 ggatttgaca aaatacctgc tacagtagtg gcaattagtg ttaccaccaa accgacctgc
    18121 aaaggtctta acccaggtaa atcccaacgc acttgcggat aattcttcac tgcatcggac
    18181 atttcatggg gttctttgac taccatcatt ttaactacgc gaatgtagta gtagatggag
    18241 acgacgctgg taactaagcc caacaagact aaccaataaa gtcctgcttg ccaacctgcc
    18301 cagaataagt aaatcttgcc gaaaaaccca gctaatggtg ggataccacc caaggaaagc
    18361 agggagatac tcaaggcgag tgttaagagt ggatcttttt gatacaagcc agagtattcg
    18421 gcaatctggt cggttcccgt gcgtagtgag aacagaatga tgcaggtaaa accgcacagg
    18481 ttcatgaata ggtagaccag taggtaaaat accatactgg cataacccgc ttgtgtgcca
    18541 gcaatcaagc caatcatcac aaacccggct tgggcaatgg atgaataagc tagcatccgt
    18601 ttcatgctgg tttgggctaa ggcgactacg ttacccaaga tcatgctgag aacggctaga
    18661 gcggtgaaga caaacctcca ctcgtcagca acgagaggga aggctgttgt tagcaagcgg
    18721 atggctaggg caaacccagc tgctttggaa ccgacagata aaaaagcgat gactggggtg
    18781 ggtgcgcctt cgtaaacgtc tggtgtccac tggtggaagg gtgcagcgga gattttgaag
    18841 ccaatacctg cgatcgcaaa aactagggca atcactaaac ctaaagattg tcccactttc
    18901 gctgtggcaa tgccattagc gatcgcacta agttcggttt gtcctccaga tagtccatac
    18961 agcagggata caccgtacaa aaatattgct gtactggaag ctccaattaa caagtatttc
    19021 agcgccgctt cgttggagcg ggggtcacgc ttggtataac ctgtcaataa gtaagaggag
    19081 atactcaggg tttctaggga gatgaaaatc atcaccaact cactagcccc agataaaaac
    19141 atccctccca aagtagcact gagcaaaata gcgatgaatt cggctaaagc agtgccactc
    19201 tgctcaacgt agcgaattga catcagtata gtggcgatcg cagacaaggc aataataccg
    19261 cgaaagacaa tactcaggtc atcactgtta aagctgccgg taaaaccgat gggattagga
    19321 gagtcccatt gaaaatatag ggcgacaatc gaagcaaata aacctgcgat cgctagatat
    19381 gcaatccagc gcgcggatgt acgccccaaa atcaaatcaa ctatcaaaac ccccaagagg
    19441 gtgagaataa caatcccctc tggcaaaatc gttccagcgt ttagctggga tgcaatatta
    19501 gcaaaatcca tgagatgtat aggttttggc gattagacat taaggctaac tctgttcact
    19561 ctagcaagtt ttctaatccc cggactagct cttttaacaa gagcttaaca gcttgggtac
    19621 agatggcgat tgcagtaact tcactgactt atcagtattt aggtgaatcc ctaagtactt
    19681 tcatacttgt tttttacagc catttttagg taattagacc atgcggtagg ggcaatttat
    19741 gtagacgcaa agcggcttcc cgcagggtat tgtccctact taatattgat tacataaata
    19801 ataatgccgc aggtgcgatc gctatgtaca aaaagctcat taataattaa taagggcaca
    19861 gtaaaacggg cggttataaa ccgcccaggc ttaagttgac accaatgagc aatgctgtgc
    19921 ccctacaata ttcataactc ctaactttat caaaaaccga ctgatggcag cttgccttgt
    19981 agcgactgaa atttagactg aacacagttg gcacaattgc aaccaagttg atcaataatc
    20041 ggattagatg tttgaatcaa atttggtgtt gccagatcgg taatttgttg tgtagatact
    20101 accgtcatca tttgggtagc gtatgtagat tttaggctag atgcgtttgc tggattgact
    20161 atcagcagca tggataccag aaatgcggga aaggcaagta aaatcagttt gactatgttc
    20221 ataatttaca caaagatagc tttgctgata cagcatagct aataaattgc ccagcttcaa
    20281 ttttaattac cggctattgc ttaactacgc ccgaatcctt gaccccgcaa aacctttgac
    20341 caaataacta attcgccctg ttcaccacct gcggccaata acttaccttg gggatgccaa
    20401 gcgaggctag aaaatcctgc tgagacacct gtgataattt ggcatacttc cttggctttg
    20461 ttccacaaac acaaccagcc gtcagccgcc gcagatgcga gaaggaagct tttaggtgca
    20521 aaggcgatcg cattgatcac acccacatga ttagttaata ctcgcgcttc ccagcctaaa
    20581 gtatcatcct ctagcttttc ccacaccaca ataccttcaa cgctagaaga tgccaatatt
    20641 ggcgcaccta ctttagtcat agcttctgac catgccaatt gacgaatttt tccagggaaa
    20701 ccacgcatca cccaagggtc ggggttgttc cattctaaaa cggtgatact gcgatccata
    20761 ttgccagaag ccaggaattt gccatcgggc gaccaagcca tagctaaact gacggtagtc
    20821 atatctaagt tgtatggttc ttcatcccag tttttactat gccaaatctt gactccctta
    20881 taaccactaa tggctaagta ttctccatca atgcgccaat ctatacccag tactgaagag
    20941 ttgtcgaaat tcagcgtcac gataac
//
