LOCUS       NZ_CP040272            29451 bp    DNA     circular CON 31-AUG-2024
DEFINITION  Nostoc sp. C052 chromosome, complete genome.
ACCESSION   NZ_CP040272
VERSION     NZ_CP040272.1
KEYWORDS    RefSeq.
SOURCE      Nostoc sp. C052
  ORGANISM  Nostoc sp. C052
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
            Nostoc.
REFERENCE   1  (bases 1 to 7828336)
  AUTHORS   Li,F.-W.
  TITLE     Complete genomes of symbiotic cyanobacteria from bryophytes provide
            new insights into the evolution of Vanadium-type nitrogenase
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7828336)
  AUTHORS   Li,F.-W.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2019) Boyce Thompson Institute, Boyce Thompson
            Institute, 533 Tower Rd, Ithaca, NY 14853, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.4.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 84.0x
            Sequencing Technology             :: Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013393905.1-RS_2024_08_31
            Annotation Date                   :: 08/31/2024 08:18:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,527
            CDSs (total)                      :: 8,409
            Genes (coding)                    :: 8,174
            CDSs (with protein)               :: 8,174
            Genes (RNA)                       :: 118
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 104
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 235
            CDSs (without protein)            :: 235
            Pseudo Genes (ambiguous residues) :: 0 of 235
            Pseudo Genes (frameshifted)       :: 84 of 235
            Pseudo Genes (incomplete)         :: 168 of 235
            Pseudo Genes (internal stop)      :: 38 of 235
            Pseudo Genes (multiple problems)  :: 50 of 235
            CRISPR Arrays                     :: 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:15:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1661946
            Orig. end                         :: 1691397
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040272.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Fay-Wei Li, Boyce Thompson
            Institute, 533 Tower Rd., Ithaca, NY 14853, USA.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..29451
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /candidate_cluster_numbers="4"
                     /contig_edge="False"
                     /product="proteusin"
                     /product="terpene"
                     /product="lanthipeptide-class-ii"
                     /region_number="7"
                     /rules="(PoyD or TIGR03793)"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..29451
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PoyD or TIGR03793)"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="neighbouring"
                     /product="proteusin"
                     /product="terpene"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /protoclusters="3"
                     /tool="antismash"
     cand_cluster    1..22357
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PoyD or TIGR03793)"
                     /kind="single"
                     /product="proteusin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22357
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12357](+)"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12357
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
     misc_feature    2..20
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 25.26"
                     /tool="antismash"
     misc_feature    622..634
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.63"
                     /tool="antismash"
     gene            complement(2043..3500)
                     /locus_tag="FD723_RS06695"
                     /old_locus_tag="FD723_06685"
     CDS             complement(2043..3500)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017746177.1"
                     /locus_tag="FD723_RS06695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_06685"
                     /product="NHLP bacteriocin system secretion protein"
                     /protein_id="WP_179064620.1"
                     /transl_table=11
                     /translation="MQETQKEDNPKKSLFRQEALDRISSPEQLDQLIQVVNPKAWIPLA
                     TIGTFLVVTLVWSIFGRLPITVTGQAILLRPRRVVQFQSPSSGQLQTLNIQAGMEVKRG
                     QAIGTIDQSQLQGQLRQQKEKLAALLSQTRERATLQKQQQGLQQRNLQQQRRILEKSLS
                     DAQALAPVLREQGLNSIQKNRAGLTLRLSQLQKQLPVSQERVTRRQSLLAAGAISQDTL
                     LQVQQEYFDRVTQITDLEAQLQQLRLKELETQQQYLQNQTSIKQNQAQLEDLTSQEIKQ
                     LQQQKEQVFTDKNQVDEVKRQIAQLELQLSSQGKIVSPYDGRVLEVTTTPGQIIQAGSL
                     IGSIQAENPAEPLVSLAFFPDRDGKQIQAGMAAQITPSTTKREQFGGIIGKVSDVTPYP
                     VGLENVRAMVGNTELAQQLAGSSAPVQVAIQLTPDSTTFSGYQWSSSRGPQQNLSSGTT
                     ASVQVRTGEIAPIAYVIPLFRSWTGIY"
     gene            complement(3500..4573)
                     /locus_tag="FD723_RS06700"
                     /old_locus_tag="FD723_06690"
     CDS             complement(3500..4573)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012257.5"
                     /locus_tag="FD723_RS06700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_06690"
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="WP_179064621.1"
                     /transl_table=11
                     /translation="MTEVLLEELLDSDINWIAQRGHKRHFSANQSIIQQGQPLDACYIL
                     LTGSLVAAVADSLATDPEMGQSLIQFSPGEIVGETAFFRSTPFPMTIRAMQDCEVLELP
                     YPAMQARLSQDPAFASRFYRAIAILLLQRFEQVLSKFSRRRGLQISTVQDAPVFLGELH
                     DSDVDWMIEQGTVEEAIAHQVLIQAGRAVEKLYVVLSGELAVAATEQKRSALNEIFSQL
                     RGDENEPSGRQILRVSRGEIAGETALLNSRLSNFIVKATVPSVLLSIPQPHLSLKLQQD
                     LAMGARFYRVLAILNADRLEAFIDRLGYTATAYRVGQPLSSTVQYEDELNLDTLDVVNV
                     GGARFDWMLQQLKVRGR"
     cand_cluster    3903..26074
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    3903..26074
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[13902:16074](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      13903..16074
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
     gene            complement(4586..5788)
                     /locus_tag="FD723_RS06705"
                     /old_locus_tag="FD723_06695"
     CDS             complement(4586..5788)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF047201.1"
                     /locus_tag="FD723_RS06705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_06695"
                     /product="hypothetical protein"
                     /protein_id="WP_179064622.1"
                     /transl_table=11
                     /translation="MSHPEIEAVSEELLNYNQNTFTQLPLDALQALSKSDLSQTSEPYL
                     EAWQQYAQEAQTQGVATVLKQYLVQLHFPIESGMSETAHYQAATRQGVRPSTNAVRSRN
                     DIDETSHLGIERSEGCCFQAPDQLSLKIHASIAGLIPVIIAGCRADFVMLIQALTRRNE
                     PTPIPLSMGACMVSGYNNWERVFRYRHQWTNQWIEQQGKSPSESDWNAEFKQLIPHKDL
                     YQDRFMILSTAPYSHVTAAELDLTEAEWSAYSLIIRLEHECTHYFTLRFLKSMKNHLLD
                     ELIADYRGIVAAIGYYRADWFLRFMGLEQYPNYRLGGRLENYRGSPSLSDRAFQGLQTL
                     VKRSAENLEQFDRAYRTAYLTPQQEIAIVLALTQSTLIDLASESGQTFIAHTVDQILCK
                     R"
     cand_cluster    6116..29451
                     /candidate_cluster_number="4"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="3"
                     /tool="antismash"
     protocluster    6116..29451
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[16115:19451](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="3"
                     /tool="antismash"
     proto_core      16116..19451
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="3"
     gene            6476..7231
                     /locus_tag="FD723_RS06710"
                     /old_locus_tag="FD723_06700"
     CDS             6476..7231
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1157: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017308551.1"
                     /locus_tag="FD723_RS06710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_06700"
                     /product="MinD/ParA family protein"
                     /protein_id="WP_179064623.1"
                     /transl_table=11
                     /translation="MAKIIAVHSFRGGTGKSNTTANLAAAIALSGKRVAVIDTDIQSPG
                     IHVLFGLEPDRLKYTLNHYLWGNCEIASAAYDVTPTEIKQANGTMFLIPSSTEISSITR
                     ILQEGYDVRLLKNGFSDLMQTLKLDYLFIDTHPGLNEETLLCIAISNMLVVILRPDRQD
                     FQGTAVLVDLARRLKVPNLLMVVNRILQRTDLAALKQQVESTYEVAVAGLFPNSDEMMQ
                     LASSDLFYLRHPNHPLSQEMQKVAQQVMV"
     gene            complement(<7291..>7438)
                     /locus_tag="FD723_RS06715"
                     /old_locus_tag="FD723_06705"
                     /pseudo=""
     CDS             complement(<7291..7438)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015955833.1"
                     /locus_tag="FD723_RS06715"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="FD723_06705"
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKGRIHDFRLFKSSGVKFGELIKVIADKGYQGITKIHRLSETAIK
                     KPKG"
     gene            complement(7471..8949)
                     /locus_tag="FD723_RS06720"
                     /old_locus_tag="FD723_06710"
     CDS             complement(7471..8949)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025869.5"
                     /locus_tag="FD723_RS06720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_06710"
                     /product="AAA-like domain-containing protein"
                     /protein_id="WP_179064624.1"
                     /transl_table=11
                     /translation="MKIPQYSAHSSHRAIDLERLLHILDDAVNLQVGKHFNTLQTLILH
                     GVWMEQSYQDIAQTAHCSETHIKKVGAELWELLSTVLAEPVSKKTLRAILERRSSELLK
                     RVAQATLPTVRVPDVEDFLEFPDGPVKLDSPFYIKHPAIETKCHQVLQQPGGFVRLQAP
                     SQMGKTTLLNRILLQAKQQGYLCVSIDIQLVDQTTLQHLDRFLQWLCTHIASSLQLPTK
                     LNDYWDITYGSKISCQNYFKNVLLPQLQAPLILAIDKLDLLFAYPNVADDFFALLCSWY
                     EQSKYNELWQKLRLILVYSMKHYVPLNLYQSPFNIGVAVELPELSMGQVSILVDRHGLI
                     WTTHQLEQLMSLVSGHPHLIRLALYHIVQNSLSLDQLLYHEFTESNPFYHHLQQHFRIL
                     EQNPKLVPVLLSILMNEPINANSLEVRQLYQMGLIRVQRGEIELRCELYRYWLRDCQSL
                     QVLSNTFNGDENLQVLLKRWFLLVQVYRLHSIAV"
     gene            complement(9307..9477)
                     /locus_tag="FD723_RS06725"
     CDS             complement(9307..9477)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FD723_RS06725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_179064625.1"
                     /transl_table=11
                     /translation="MLQTGGYLSTDNWGWSFPPTSNKARSLIQQNHLNFSQESKSTADV
                     SWSLERLKYVN"
     misc_feature    9605..9620
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.3"
                     /tool="antismash"
     CDS             complement(9760..9882)
                     /gene="allorf_1671706_1671828"
                     /locus_tag="allorf_1671706_1671828"
                     /protein_id="allorf_1671706_1671828"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRLTSSREGIDSVSNTAKAIEDEGVPLNIWGKAPSRCGIL"
     CDS_motif       complement(9832..9882)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRLTSSREGIDSVSNTA"
                     /locus_tag="allorf_1671706_1671828_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9760..9831)
                     /prepeptide="core"
                     /locus_tag="allorf_1671706_1671828_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.90"
                     /molecular_weight="2448.8"
                     /monoisotopic_mass="2447.3"
                     /core_sequence="KAIEDEGVPLNIWGKAPSRCGIL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRLTSSREGIDSVSNTA"
                     /leader_location="[9831:9882](-)"
     gene            10001..10552
                     /locus_tag="FD723_RS06730"
                     /old_locus_tag="FD723_06715"
     CDS             10001..10552
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proteusin: TIGR03793"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03793.1"
                     /locus_tag="FD723_RS06730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_06715"
                     /product="NHLP leader peptide family RiPP precursor"
                     /protein_id="WP_256875099.1"
                     /sec_met_domain="TIGR03793 (E-value: 1.1e-23, bitscore:
                     81.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSSESGQTVEMIATGHIPNLEAQLITQAVQDPAFRQKLIADPRA
                     VLSEQGLEIPDGIQINVLQESPSQYYLVLPALHGSPTEGAAELSDEELEAVAGGNLDSQ
                     NSNWTGCASGRSGCVATNGCSIAAVIGSGIAATAIVAGGVAAASVTAGALTAASPLVAV
                     AATGTAAACGIGQAAASKYG"
     gene            11205..11753
                     /locus_tag="FD723_RS06735"
                     /old_locus_tag="FD723_06720"
     CDS             11205..11753
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proteusin: TIGR03793"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03793.1"
                     /locus_tag="FD723_RS06735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_06720"
                     /product="NHLP leader peptide family RiPP precursor"
                     /protein_id="WP_256875100.1"
                     /sec_met_domain="TIGR03793 (E-value: 2.1e-22, bitscore:
                     77.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTEPTPTPEMNSTGRMPNLEAQLITQAIQDPAFWQRLLNNPKA
                     VLAEQGLNVPDDVQINVLQESATQYYLVLPALELPTASGEVAELSDAELEAVAGGANLD
                     SQNANWTGCASGQSGCVATNGCNAAAQVGFGVASFVGATATGLALASATAALGTPAAMA
                     AGGAVAIACAGAATATKLA"
     gene            11833..12357
                     /locus_tag="FD723_RS06740"
                     /old_locus_tag="FD723_06725"
     CDS             11833..12357
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proteusin: TIGR03793"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03793.1"
                     /locus_tag="FD723_RS06740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_06725"
                     /product="NHLP leader peptide family RiPP precursor"
                     /protein_id="WP_256875101.1"
                     /sec_met_domain="TIGR03793 (E-value: 5.5e-25, bitscore:
                     85.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTEPTPTSEMTATGRMPNLEAQLITQAIQDPAFRQRLLNNPKA
                     VLAEQGLNVPDNVQINVMQESPTHYYLVLPALETPDAATTELSEAELEAVAGGGGTLDS
                     QNSNWTGCASGRSGCVATNGCSVAATATVMVASAVGAVGAGIVTGGVAAGLTAGLCIVG
                     SSATGVGTQAR"
     gene            12459..13898
                     /locus_tag="FD723_RS06745"
                     /old_locus_tag="FD723_06730"
     CDS             12459..13898
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017532.5"
                     /locus_tag="FD723_RS06745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_06730"
                     /product="phytanoyl-CoA dioxygenase family protein"
                     /protein_id="WP_218651803.1"
                     /sec_met_domain="PhyH (E-value: 1.1e-24, bitscore: 86.4,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSEGLLPLVKKEEAEPGMPGHLASKFPHSSLSTPILKRSSREPA
                     MPQENVARFFAAVLEGKVPIEPEQESCTSNPERFVHLSEKFGYPFSLTELQAEIARHIQ
                     KPHILQLFEAALHDEALKRMLKQASQPAQLQAALLPLGYSLTPDELNAVIYTCCHCVRG
                     LFCECRAGGIGKQVFERSRITSTDLLLPALAEDYAIAPDQIRSFHQDGHLRLRNVLTPE
                     EIAVYRPALAAAVDRHDLEQKAMEKSVSGQSQGWKFVENLWRLDPAARKFTLAKRFGKI
                     AADLLRVDAVRLFRDQSYFKKPGGGNTPWHQDSYFMPLDTHQVITMWVALSDVTTEMSP
                     MIFVSAAHRRGYQGASMPNDESMDEFERNLDAKGWQRMSYGAMVAGDASFHTGWTLHSS
                     RENTSQQTREAMVIVYYADGARVAIPPMPRNPTPPENFAAIIRQHNLSTCLPGLKSGDL
                     AETLMNPIVYQRQPSESLSGY"
     gene            13903..16074
                     /locus_tag="FD723_RS06750"
                     /old_locus_tag="FD723_06735"
     CDS             13903..16074
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.5"
                     /locus_tag="FD723_RS06750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_06735"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_179064626.1"
                     /sec_met_domain="T2TS (E-value: 8.1e-14, bitscore: 49.5,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLFSLENSLQAIAPHLSPLIAPDALERLQAIGRCFPDALTYSYG
                     FEARLHPAEPTVDFAIHITPTERDILAGLHPTIKLPDVFQQHPVWQRIRQFCLEWADPS
                     SELHYQVNDLWLEFDAHQSQNSPDVPVPGLFVSPVPPQGGIVPDYTWIWRKALPLLCDN
                     DMAEGVELNVIQCIHNLPTQVGIFQFGFMFGRKIEAVRFCLSGSPIQMIPHLNQLGWQG
                     SLQEIERLFALLYSYCDGAILDIDVGSLIYPRIGVEGIYISRYLSCVNGQWASLLNHLV
                     EQNLCEPFMRDALLKYAGYTVNKPLHQRIYIRGLSHVKLLYQPGKPLSSKVYFGVMHKP
                     ISASPTLSAGLQTRAGTSLANSAAVASPRATVTQSLQAAITFLLTSRDSQGWWTDFHLG
                     AGLSDEWVTGYVGTTLASDSAIAVDPQALDAAQTAWTLLQARRHRITGLWGFNRFPPGD
                     ADSTGWVLQLAHALGEPQSERVQQALQSLREHWRSNGGVSTYGSAEAIRSFIYAAPEQS
                     MEGWCGSHICVSAALAALPEVRDQLLDYLHSTQNSEGSWSAYWWHDLEYSTALAAEALA
                     VSDDSSEAIANAVQWALQRLSPTGFIATNDHPLGSPFATAWGLRLLLLGKPEQTEAAIA
                     AVIRWLLTQQQLDGSWESSARLRVPFPDDLDPNQFDRWVYHDKIEGSLNFDQHHVFTTA
                     TVLQALFKAKSHLPFNADAESDRPLTAVD"
     gene            16116..19451
                     /locus_tag="FD723_RS06755"
                     /old_locus_tag="FD723_06740"
     CDS             16116..19451
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="FD723_RS06755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_06740"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_179064627.1"
                     /sec_met_domain="DUF4135 (E-value: 9.7e-99, bitscore:
                     329.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.7e-58, bitscore:
                     195.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAISKIEPASSRLHAAALRRIVARSSTLYERLEVAHVLPTSEPL
                     AEALQQSRIDAWCDAIAKGDFDRFQRCLSWDGITLDQAKQAIQTVTLREDAPLPDWAEM
                     LHQVFLLMTAQASEQSPTYRFFDPQAPLPFQELFAPFVLIAQQELSRRTGAAARRLTEP
                     VHALLERSLLGQLIDLSAQSISLTFTSWRTGQQSSFGRFLSQMGSISGRNLYLRFVQEM
                     LQGQFVSFLEEYATLARLLITLTNLWIEAQQEFLQRLDADWLMIGERFGKDISNAQVVA
                     IQVELSDRHRGGRSVIAFRIGDDLPLVYKPKSLGIDRAYNDLLLWLNEQGCLLPFKAVE
                     VIDRGDYGWVEYVLSWHCADVHQVKRHYQRAGMLLCLTYVLEATDCHHENLLACGEYPV
                     LIDLETLLQPRPDLESAEYLQTAHRIAIYQLSNSVARTALLPVWEGEDDADSSFDYSGL
                     GSQVQQNRTYKGLQWTAVNTDQMALTLQDIAIEPSFSHMPMLDGKPANLINSIESVAEG
                     FQQLYYFLLEKRELLLAENSPLKAMANQTIRFLFRRTNIYAKILKQLAHPNYLKDGVDR
                     SIRLEVLKRSAAMEANQPKFWSMIDVERQSMEQLDIPMFTLQSDREILTLSSQQQVEQF
                     FEGSGFDLMWQRLQSLSLADMSMQVQYIRAMLGLRGIAPHEMSLREQDGSAEDSFSSEI
                     LDDTALLAEAIAITQRIQDRAIHAPDGSVTWLSPQFSLQHQRFELQPTNTSLYDGKVGI
                     ALFLAALAKVTGETSYKELCLQALQDFQRSKEAVLFSTKDPNFNLNLGLSAGLASSMYG
                     ITCISRLLSDCNLLEMALDMVSLVEPDVIAQDTYLDILGGTTGILLSLITLYEMTQDSA
                     ALEAAIACGQSLLARSVPTEGGRAWRTLSGRLLTGFSHGAAGIAYALLKLAHITGDRAY
                     QLAAEAGIAYEQSCFLPTVSNWCDLRDFSQFLLATGSTEAPPLMSSWCHGATGIGLGRL
                     GGLTLLDNAAIRQDIQSALQTTYATLEQKREMVDQLCCGSMGRVDFLITASDRLGQPEL
                     LANARAQASQVIHLARSKGGYTAEPGLHQSIYVPGFFRGEAGIGYTLLRLIAPQQLPSI
                     LLLE"
     gene            complement(19652..20080)
                     /locus_tag="FD723_RS06760"
                     /old_locus_tag="FD723_06745"
     CDS             complement(19652..20080)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FD723_RS06760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FD723_06745"
                     /product="hypothetical protein"
                     /protein_id="WP_179064628.1"
                     /transl_table=11
                     /translation="MHFLAMNQRWIALPLSMICAIFYAPIGEANPTSNSHTTPLIAQST
                     CSAKDLSRSTPPFPCVSPKAFSCLKKNNASNGGSLEYRGDTSGEIVVKSDVVGQVALLE
                     FNYDQSTQTLNLNVKQKNFPVQEQQIWDGFKNTLSKCR"
     gene            complement(20091..21359)
                     /locus_tag="FD723_RS06765"
                     /old_locus_tag="FD723_06750"
     CDS             complement(20091..21359)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017739726.1"
                     /locus_tag="FD723_RS06765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_06750"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_256875102.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 4e-22, bitscore:
                     77.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPFTPLPLFQLSLYPPHLMFLNDVDLILLTVLSVSILTLTAYLI
                     SLHQAIKQLPKITTHSEGTFSEVELPKISVIIPAFNEEENIADCVQSVVSSTRLSAKQL
                     DVWIVDDQSSDRTPEILQALNIQLADPRLNILTGKPRPTDQFWTGKNWACQQGAERANG
                     DFLLFIDADVRLKPDAISAVVATAIAQQLDFLTSIPTIVCDSLVEWLVQPLMFINLTIS
                     LNSKVVKNPKTKTTYALGPFLLFRASTYNAVGMHRAVAGYPAEDVAFARRLKQSGFKLQ
                     HYLGANLASLRMYRNWSALWEGWTKILYVGAQRSVMLMLLLIWVMLLIYTIPWIGFVIA
                     IAQVLKHPNLFHFAEMGLTGLAILLQYQVRRQGSRALGTSTKYWWLQSLGGLLIAVLAI
                     ASIIKVETGWGWTWRGRKLVSVK"
     misc_feature    complement(21383..21398)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.31"
                     /tool="antismash"
     gene            complement(21652..26958)
                     /locus_tag="FD723_RS06770"
                     /old_locus_tag="FD723_06755"
     CDS             complement(21652..26958)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.5"
                     /locus_tag="FD723_RS06770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_06755"
                     /product="AAA family ATPase"
                     /protein_id="WP_179064629.1"
                     /sec_met_domain="Pkinase (E-value: 1.2e-32, bitscore:
                     111.9, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTIAGYEVLSTLYEGSRSLVYRGRSNHQPQSVILKVMQAEYPSL
                     EELSRYRLEYDIINRLHGAGVAAAYDLIKYRHGLALVLEDFGGESLYQVLQQRRLDLEE
                     FLELAIALTEIIGQVHAANVIHKDITPANILLHPISKQVKLIDFGNATVLSRENPSMSS
                     PSVLEGTLLYLSPEQTGRMNRTLDYRTDFYSLGATFYELLTGTPVFAVTDAMELIHCHL
                     AKQPEPPHLIHPEIPVMVSQIVLKLLAKNAEDRYQSAYGIRADLQQCWQQIRQGNQIAS
                     FTLGQEDASGKFQIPQKLYGRELEVETLLTGFDRVVTGGNHKSELMLVAGYSGIGKSAL
                     VNEIHKPITRKKGYFISGKYDQFQRNIPYSGLIQAFQELLRQLLTESPAQIDRWRSQLL
                     NTLGNNGQVVIDVIPEVELIIGKQIAPPELGSREAQNRFNLVFQNFIKVFTQSEHPLVI
                     FLDDLQWVDSASLKLINRLMTSADSQFLFLVGAYRSNEVSPVHPLMVAIEEIRQAKVIV
                     SQIELSPLTLTNITQLILDTFNCTAEQATPLAELLLQVTDGNPFFTNRFLKSLYEDGLL
                     NFDEQLGRWQWDLVQLRAAPVPDNVVELMTGKMQKMPPQTQRALKLAACIGNQFDSQTL
                     SIISESSPATLARDLWQGVQEGLILPLGENYKFTSIEEQTSADLVVVFKFLHDRVQQVA
                     YSLIPDAEKQTIHRQIGQLLLDHTPPEKREERIFDIVNQLNIGINLITDSAQRNELATL
                     NLIAGKKAKDSAAYETAIRYLLTGIDLLGEQSWQRQYALTLALHEEAAESAYLNGDFAE
                     TERLVERILHDAKTILDCVKAYQVRVGAYTAQNNLQAALDTIVSAMARLGEPLPRNPNR
                     LRVGLELLRTRFWIVGRLSLAQLESLPPMTDPYKLAAVQLLGSAAMASVNVAPLLVAVL
                     ALRVVNLVVRYGSSSSSSVQGVAYGVMLRVGLGDIDGAYRFSQVSLRILARFNDRIYRT
                     MTIVAYESCIRHWKEPLRPSLAVLLNAYQEGLELGNQEYASIAASAYCIHQLFLGEPLS
                     TVANAFQEYTAQFRRFNQEAIVYQTQPWHQLVLNLQGDATEPTRLVGSAFNEDEMLPVF
                     INNRLGIPIFYTYIAKAMWLYYAGDYAGSLQAARLAKPWEESAPVTPGYANRYFYESLA
                     CLALCAIATKADRRRYLRQVKSNQRQAKQWAKYCPENYQHRYDLVEAERLRVLGNNLNA
                     MRSYERAIQAARTQEYTHEEALANELAAKFYFNLGQERVAQGYLLDARHNYLRWGATFK
                     VEQIDAQYQQLRDRSTLDLMTGISISSKTSSRSLGQDLDLETVIQAAQAISGEIVLDRL
                     LEKLLQLAIENAGAQKGYLLLNHSSELRIEAAGHIIDRDIEIIVETRPLTDTQLPISIV
                     NYVQRTRENLVLRDAVQEGLFTVDPYIFQTQPRSILCAPILNQGNLSGILYLENALATD
                     TFTSARLTVLNVLSAQAAIALENASFYRTLEQKVEDRTADLAQANQEIILLNQRLQSEN
                     LRMSTELDVTRQLQRMILPKESELSQIPGLEIAGFMEPADEVGGDYYDVLQDRGLVKIG
                     IGDVTGHGLESGVLMLMVQTAVRTLLINQETDAVRFLSTLNRVIYENVQRMNSDRNLTL
                     TLMDYHAGRLRLSGQHEEVLIVRADGAIELVKTNDLGFPIGLVEDISQFVSYLDVELQS
                     GDGMILYTDGITEAANLLDELYGLERLCQVVSQHWQKSAQEIRYTVIEDVRHHIGEQKI
                     FDDITLLVIKQK"
     gene            complement(26973..28754)
                     /locus_tag="FD723_RS06775"
                     /old_locus_tag="FD723_06760"
     CDS             complement(26973..28754)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0046930 - pore complex [Evidence IEA]"
                     /GO_function="GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0033212 - iron import into cell [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033921.0"
                     /locus_tag="FD723_RS06775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FD723_06760"
                     /product="iron uptake porin"
                     /protein_id="WP_179064630.1"
                     /transl_table=11
                     /translation="MGRAWLKSAVLAVILLSTSKGLAAPPRVEDGASPTRLDEPLNPSE
                     DALTQVTSVSQLTDVKPTDWAFQALQSLVERYGCIAGYPNNTYRGNRSLTRYEFAAGIN
                     ACLDRVNELIATATTALVTKEDLATLQKLQAEFATELGTLRGRVDSLETRTATLKAQQF
                     SATTRLNVLSSFNVSQAFASGDVKAEGVPIPNSLPAARLALRSPNPATGKLEPIVTTTS
                     RTASTTFSQSTYLILSSSFSGRDTLTTILAAGNGSPPSSTYSSAGFASTFGVPYADSNP
                     VNPLAPNSIGLFELKYQFPISNSVNAVVGPRILTFRHFDVNPYTNVVNGASGLNSYQST
                     LANSGLSGAGAILNWQISSKLAFQAGYLNRNDASLQYFGGDGAANPERGLFNGSYSLLA
                     ELAYSPSPQTTLRFLYTRSHSQAPPASPPSQPNFPFFLTNSLRGVVDDGFGGSLNDIDS
                     DNFVFNFDWKIAPTFALFGRYSYTQAGINPVNPLIQSGSANVQAFQLGAALPDLGRKGA
                     LGTLSLVVPFNILSGRQFFVAGNGNGGTEFDLEATYAYPISSNLTIVPTFFATFNANNF
                     SDNPTVFGNVLRLQFLF"
     misc_feature    28760..28776
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.36"
                     /tool="antismash"
     misc_feature    complement(28762..28774)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.31"
                     /tool="antismash"
ORIGIN
        1 aattgcgatc gatgatcaat tcagtctcag cgtctagggc actggttgcc tcatctagca
       61 ctaaaattga gggattccac accaaagcac gcgcaatttc aagccgctgt cgttgtccac
      121 cgctcaagtt cattccccct tcaatcaagg aggactcata tccgcctggc attgagataa
      181 tcaagtcatg aatggcagca tcctgacaag ctcgtactat atcttccaag ggaaccgtgg
      241 catcccacag ggtcaaattt tcacgcaccg ttccagcaaa cagaaagatt tcctgttcga
      301 ccattgccag cgaattggct aaaaccgtcc gaggaatgcg agtgtactca atcccatcca
      361 atcgaatttc accctgccag ggttggtaca atcctgtgac taacttggca acagtagact
      421 ttccagaacc gctacccccg accaaagcga ctcgctgacc tgggtgaaca gtcagactaa
      481 aatcgtcaat caaaggagct gccattcggc tatagccaaa ggtgagatga ctcaattcaa
      541 ctgtgccttt taagcgaata ttttgagcag tagcttgcgg agtggatgcg aacgactgct
      601 cacgagtcac cataggatca actggatttt gcaaaacatc atctagacga ttcaaatccg
      661 cttccaggtc ttgaagcgta gtgccaaagt tcagcagaga gtttacaggg cccagaaagc
      721 tctgcgtcag tgattgataa gccatcagca tcccaatact cagactgcca cccataatcc
      781 gaaatccacc gacaactaga attgtggtcg tcgccatcgc tccgagcaaa gtcggtaaag
      841 tggagagcat ctggttcggc acaaccgcct ctttctgtgc attgatcgtc ttggcgtagg
      901 aacctgcgaa tttagcgaac acatcggatt ctagccctga cgcttttacg ctttcgatcg
      961 agagcaaaga ccccacaacc atccccaaag ccttaccgcc ttcctgagcc agtttgctgt
     1021 ttgcatcctt acgactggta gctagaaatc taagcagcac caaattgaga atggcaaatg
     1081 taatagcaac tagcgttagc acccaatcgt aggcaaacat aatgaccgca taaaacacaa
     1141 tcatcaccaa atcgatcgcg gtggttccta actgcccagt aattacccca gaaactttat
     1201 cgttcaaagc actgcggttg ctaatttctc cagcataacg ctgggcatag aagctaacag
     1261 gtaagcgcaa aatatgccag agaaaattgc ctgccattgt cgttgagagt ttaatcgaca
     1321 ggcgaagcag atagtttaat cgcatctgcg ctaatagtcc ctgaaatagt gctgtcacga
     1381 tcatggcaat taataacgga cgtatccatt cttgacgacc ttgaacaagc acttcgtcaa
     1441 caaaaacttg gctaaaaaca ggaattgcta ggcggggtaa cgtcaggagt aatcctgcaa
     1501 tcaggcaaaa cgcgatcgcc tgctgagaat gtttcaatcg accgatcaag gctgataaaa
     1561 ttcccggttt ctttcctcct ggcttaaact cagatcccgg ctctaggact aacacgatcc
     1621 cggtataact ctggctgaat tcttcctgcg aaacctttct gcgtcctgat gctggatcgt
     1681 tcaggtaaac ccaattctgc gtaaaacgct cgacgactaa aaaatggtta aaattccaga
     1741 atacgataca ggggaagcgc acatctacaa gcttctcgat cggcagctta aacccctttg
     1801 cttccaatcc ataaagccgg gctgccttca ccatatttga tgctttactc ccatctcttg
     1861 aaactccgca ttcgcgccgt agctctgata gtggcacgat ccgctgatag taagctaaaa
     1921 taatccccaa tgccgctgct ccacactcag cattctccat ctgaatcagc gttggcgttc
     1981 gactggtatc gaatccaaat cgattccacc tggatctaat tctggataaa aactgggtca
     2041 tattagtaga ttcctgtcca tgaccgaaac aacggaatca catacgcaat cggagcaatc
     2101 tcacccgtgc gaacctgaac gctggcagtg gttcctgacg atagattttg ttgcggccca
     2161 cgggatgaac tccattggta accgctaaag gttgtactat cgggcgtaag ctgaatggca
     2221 acctgtactg gagcgctact ccctgctaac tgttgagcta gctcggtgtt cccgaccatt
     2281 gctcggacat tctctaaccc caccggataa ggagtcacat cactcacctt gccaatgatg
     2341 ccaccaaact gctctcgctt tgttgtactc ggcgtgatct gtgccgccat tcctgcctga
     2401 atttgctttc catcgcgatc aggaaaaaaa gctaaactta ccagtggctc tgctggattt
     2461 tctgcttgaa tcgaaccaat taaactccct gcctgaatga tctgtccagg agttgtcgtg
     2521 acttccagca ctcgaccatc ataaggactc acaattttac cctgactcga aagctgcaac
     2581 tctaactgag cgatttgccg tttcacttca tctacttgat ttttgtccgt aaaaacttgt
     2641 tccttttgtt gttgtaattg tttaatctct tgcgatgtca aatcttctaa ttgtgcttga
     2701 ttttgtttaa tagaagtttg attctgtaga tattgctgtt gagtttcgag ttcttttaat
     2761 cgaagctgtt gcagttgcgc ttctagatcg gttatctgag tgactcggtc gaagtattcc
     2821 tgttgaactt gaagcaaggt atcttgacta atcgctcctg ctgcaagtaa tgactgtcgt
     2881 cgtgtcactc gctcttgtga cacaggtaat tgtttctgaa gttgcgataa tcgtaaggtt
     2941 agtccagccc gattcttttg aatcgaattc aatccctgtt ctcgcaggac aggagcgagt
     3001 gcttgagcat cacttaaact cttttctaga attcgccgct gctgttggag atttcgttgt
     3061 tgtaaccctt gctgctgctt ttgcaaagtt gctcgttcgc gggtttgaga gagtagtgct
     3121 gctaactttt ctttttgttg ccgcaactgt ccctgaagtt gggattgatc gatcgtcccg
     3181 atcgcctgcc ctcgtttcac ctccatccca gcctgaatat ttaaagtctg aagctgtcca
     3241 ctgctaggag actggaactg aacgactcga cggggacgca acagaattgc ttgcccagtc
     3301 accgtaatgg gcagccgccc gaagatgctc catactaaag tgacaaccaa aaatgtcccg
     3361 atcgttgcta aaggtatcca ggctttgggg ttgacaacct ggatcagttg atcgagctgc
     3421 tctggggatg aaattcgatc gagcgcttct tgtcgaaaca agcttttttt aggattgtcc
     3481 tctttttgag tctcctgcat tatctacctc gtactttcaa ttgttgtagc atccaatcaa
     3541 atcgcgctcc cccaacgtta acgacatcga gtgtatcgag attgagttca tcctcatact
     3601 gcactgtact agataacggc tgtccaaccc gataagcagt cgcagtataa ccgaggcgat
     3661 cgataaatgc ttccagtcga tctgcattca aaatcgctag cacccgatag aaacgtgccc
     3721 ccattgctag gtcttgttga agtttgagtg acaagtgggg ttggggaatt gacaataata
     3781 ctgaaggcac ggttgcctta acgataaaat tagatagacg cgagttcaga agcgcagttt
     3841 ctcccgcgat ctcacctcga ctcacccgga gaatttggcg accgctcggt tcattttcgt
     3901 cgcctcgtaa ctggctaaaa atctcattga gggcgctacg tttctgttca gttgcggcaa
     3961 cagcaagttc cccactcagg actacataga gcttttcgac tgcacgacct gcctggatca
     4021 acacctgatg agcaatcgct tcttccacag ttccctgttc aatcatccag tccacatcac
     4081 tatcgtgcag ttctcccaaa aatacaggag catcttgcac tgtcgagatt tgaagtcctc
     4141 gacgacgaga aaacttacta aggacttgct caaaccgctg gagtagaagg atcgcgatcg
     4201 ctcgataaaa tcggctggca aaggctggat cttgactcag tcgagcttgc attgctgggt
     4261 agggcaactc cagtacttca caatcctgca tcgcccgaat ggtcatcgga aagggagtag
     4321 atcgaaagaa agcggtttct cctacaatct ctccaggtga gaattgaatc aatgactgtc
     4381 ccatttctgg atcagtcgct aaactatcgg caacggcagc gactaatgat cccgttagca
     4441 aaatgtagca ggcatccaaa ggttgcccct gctgaataat cgattgattc gcagagaaat
     4501 gacgtttatg ccctctctga gcgatccagt tgatgtcact gtccagcagt tcttctaaca
     4561 acacttcggt catagctgcc gtttctcacc tcttgcataa aatctgatcg actgtgtgag
     4621 caatgaatgt ttgtcctgac tctgaagcaa ggtcaattaa ggtggattga gtgagtgcga
     4681 gaacaatagc aatctcttgt tggggggtta gatacgctgt gcgataggca cgatcgaatt
     4741 gctctagatt ttcagccgat cgtttaacga gagtttgcaa tccttgaaag gctcgatctg
     4801 agagactggg actgcctcga taattttcta atcgtcctcc caatcgatag ttggggtact
     4861 gctctaatcc cataaagcgc agaaaccagt ctgcccggta atatccaatc gcagcaacaa
     4921 ttccacggta atctgcaatg agttcatcaa gtaaatgatt tttcatcgac ttcaaaaatc
     4981 gcagggtgaa gtagtgtgta cattcgtgtt ccaaacgaat gatgagagag taagcactcc
     5041 attcggcttc tgtcagatct agttcagccg cagtcacatg actgtagggt gctgtactca
     5101 agatcatgaa tcgatcctga tacaaatcct tatgtggaat cagttgctta aattctgcat
     5161 tccaatcgga ctcactcgga cttttaccct gttgttcaat ccactggttt gtccactggt
     5221 ggcgataccg aaaaactcgc tcccaattat tatagccact taccatacag gctcccatag
     5281 acagcggaat tggagtgggt tcattgcgtc gtgtcagtgc ttgtatgagc atcacaaagt
     5341 ctgctcgaca ccctgcaata atcacaggga ttaaccctgc gatgctggca tggattttta
     5401 aactgagttg atcgggggct tgaaagcaac acccctcaga gcgttctata cctaaatgac
     5461 ttgtctcatc aatatcattt ctcgacctga cagcatttgt gctagggcga accccctgtc
     5521 gagtagcagc ctgatagtgt gctgtttcac tcataccgct ttcaatcggg aaatgaagct
     5581 gaactaaata ttgttttagg acggttgcca ctccttgcgt ttgcgcttcc tgtgcatatt
     5641 gctgccaagc ttcgaggtac ggttctgaag tctgtgagag atcggattta gagagtgcct
     5701 gaagcgcatc tagaggaagc tgagtaaaag tgttttggtt atagttaagc aattcttcag
     5761 acaccgcttc aatttcagga tgactcattc tctccagcaa ttccaaattc ggaatgtatt
     5821 gcgagataca gatgaattca caacaatcgg cattatgatc cttgcaattt aaactgagat
     5881 tttgacgaat cattttccgg acatacacat aattcctgtt ttgtctatat cgaaaaaaca
     5941 aggactatta ctgcaattaa ttctggcaaa agaggctgaa atgcccttct gtccttgaat
     6001 ttggaattgc tgcattctct gaaactgaag aacttaagtg caaactgggc gtatatttga
     6061 aggcatcagt ctttcttatg caaaagtagt atgaacggag atagccccat ccaattggta
     6121 ctgttgaaac cagagtttaa ttgaacgatg aaacctgcac aaagttgagc tttgagaatg
     6181 acatctttca gcagtatcta tcgctctcag aatatcacta atctcaaaaa ccctggtaca
     6241 ttgcctaact atttttactt aactttacgg ttccattgat agttgttttc cgatagttat
     6301 cgcaatggag tgaaggatca gcggtagaat gaagaagcat ttgagttcat tcaatgaagt
     6361 aagattcacg gcgctatacg atttgggact ggacgttgcg tgactgatga aaagcaagca
     6421 atacctctcg tttactagca cctcagttca gtagatccaa tggggataac aatatatggc
     6481 taagattatt gcggttcact catttcgtgg aggcacaggc aagtcaaata caacagcaaa
     6541 tttagcagcg gcgatcgctc tatcgggtaa gcgtgtggct gtgattgata ctgatatcca
     6601 gtctcctggc attcacgttc tatttggatt agagccagat cggctcaagt atacgctgaa
     6661 tcactatttg tggggaaact gcgagattgc ctctgctgcc tatgatgtca cccctactga
     6721 aattaagcag gcgaacggca cgatgtttct cattccctcc agtactgaaa tcagcagtat
     6781 tactcgaatt ttgcaagagg ggtatgatgt gcgactgctc aaaaatggat tcagcgatct
     6841 gatgcagacg ctaaaactgg attacctctt cattgatacc catcctggac taaatgagga
     6901 gacgttactt tgtattgcga tttctaatat gctggtggtg attttgcgcc ccgatcgtca
     6961 agacttccag ggtactgctg ttttggtcga tttagctcgt agactgaaag tgccaaatct
     7021 cctaatggtg gtgaatcgaa ttttgcaacg caccgatctg gctgcattga aacagcaggt
     7081 ggaatctacc tatgaagtgg ctgttgctgg attgtttccc aatagtgatg agatgatgca
     7141 gttggcgagt agcgatttgt tctatttacg ccatccaaat catcccttga gtcaggaaat
     7201 gcaaaaggtt gcacaacagg tgatggtctg attgcaggtt gtgtcgtaaa tattttttag
     7261 tcacaaacga agtatctctt tcgtattccg ttccttttgg ttttttaatc gctgtttcac
     7321 tcaatcgatg aattttagta attccttgat agcctttatc cgctatgact ttgattaatt
     7381 ctccaaattt tactccactg cttttaaata gtctaaaatc atgaattctc cccttgccat
     7441 aagcttgaat ctcaagctct ttcatcccaa ttagacagct atggagtgga gccgatagac
     7501 ctgtacgagt aaaaaccatc ttttcagcag aacttgcaga ttttcgtcgc cattgaatgt
     7561 attcgataaa acttgtaaag attgacaatc tctcaaccag tatcgataca attcacaccg
     7621 caactcgatc tcaccccgct gcactcgaat taaccccatc tggtagagtt gacgtacctc
     7681 tagagagttt gcgttgatgg gttcgttcat caagattgag agcagcacag gaaccaactt
     7741 tgggttttgc tccaaaatcc tgaagtgttg ctgtaagtga tgatagaagg gattggactc
     7801 tgtaaactca tgatagagaa gctgatcgag agatagagag ttttgaacaa tatgataaag
     7861 cgcgagtctg atcagatgcg gatgaccact gactagggac atgagttgtt ctaattgatg
     7921 agttgtccaa atgagtccgt gacgatcgac tagaatactg acctgaccca tacttaattc
     7981 gggtagctcg actgctactc cgatattgaa tggagattga tatagattga gcggcacata
     8041 atgtttcatg gaatagacta gaatcagccg caacttctgc cacaattcgt tgtattttga
     8101 ttgttcgtac caggaacata agagcgcaaa aaaatcatca gcaacatttg ggtaggcaaa
     8161 cagtaaatct aatttgtcga tcgcaaggat cagtggcgct tgaagttgag gcagtagaac
     8221 atttttgaaa taattttgac aactgatttt gctgccgtag gtgatatccc agtagtcatt
     8281 caattttgtc ggcaactgga gactactcgc aatatgagtg cagagccact gcaaaaaacg
     8341 atcgagatgt tgtagtgtag tctgatcgac gagttgtatg tcaattgaaa cacagagata
     8401 cccctgctgt tttgcctgaa gcaaaatccg attcagcaga gtggtctttc ccatctgtga
     8461 gggtgcttgg agccgaacaa atccgccagg ttgttggagt acctgatggc acttggtttc
     8521 gattgcagga tgtttgatat agaatggaga gtcaagttta acaggaccat caggaaactc
     8581 taggaagtct tcaacatcag gcactctaac tgtcggtaaa gtcgcctgag caaccctttt
     8641 tagaagttca ctactacgtc gctccaagat cgctcttaat gtttttttac tcacaggttc
     8701 tgctaatacg gtagaaagga gttcccaaag ttcagcgcca acttttttaa tgtgggtttc
     8761 cgagcagtga gcagtttgag caatgtcctg atagctttgc tccatccaaa ctccgtgaag
     8821 aatcagggtt tgtagtgtat tgaagtgctt accaacttgt aaattaactg catcgtcaag
     8881 aatgtggagt aagcgttcca gatcgattgc gcgatgggag gaatgagcag aatattgagg
     8941 aatcttcata gcatgttatg gcagtataaa tagagcaaat gttaacttaa gcaaatagac
     9001 aagcttcacc gatcgttcct ctgtcaccct gatggtatga gagcggaaag tatggatgaa
     9061 gtctttaaat cgtcgtggcg taccgattcg caaatccgaa gacctgcgag aacttggact
     9121 tgatagcagg caaatctaac aatccattag ggattgcttt aggtcgcgat cgcataccac
     9181 cgtgaacaga ggcaatgact gaaccccgat gagaaaaaat atagcaagat taggatactt
     9241 tttaatactt tacaccttat gtgaattaaa aacgcccaag ctatagcttg ggtttcaggc
     9301 tgtggtttag ttgacgtatt taagcctttc cagactccaa ctcacatcag ctgtactttt
     9361 tgattcctgg ctgaagttca agtgattctg ctgaatgagc gatcgcgctt tattggaagt
     9421 cggcgggaaa ctccatcccc agttgtctgt agagagatag ccacccgtct ggagcattgg
     9481 tgaatctttg ctatactcta tctccttgga gatggagtat tttattgttc gtgttctacg
     9541 tctttacata tgtttttaat tttccggtgc ttttcgccaa agtggatacc tgttgatacc
     9601 agatttcact tttgttttac tggagtctct ggtaaaaaca atacagggtt ggcgtagagg
     9661 atgttttgtc caaggtcttc aatcgttcac cctaaaatct ggaattcata atgttgatga
     9721 ctctgagcgc ccttggagtc gctatctgat ttgtgaaggt taaagtattc cacaccttga
     9781 gggggctttc ccccaaatat taagtggaac tccttcatct tctatagctt ttgctgtatt
     9841 agagacagaa tctatccctt cccttgaaga tgtcaatctc ataatgcgct aagtctatcg
     9901 attacgacga atcatgcgat cgtagttgct ttgatatgag caattgcaaa ttgtggcacg
     9961 gcttaattca gtcaattact tgattttaag gagattaagg atgtctagta gtgagtccgg
    10021 acaaacggtt gagatgattg caactgggca tatacctaat ttggaagcgc agttgatcac
    10081 tcaagcagtt caagatccag catttcggca aaagctaatc gctgatccta gagccgtgtt
    10141 gtccgagcaa ggactggaaa ttccggatgg catacaaatt aatgtgttgc aggaaagtcc
    10201 tagtcaatac tatctcgtac tgcctgcgct gcacggttct ccaactgaag gtgccgctga
    10261 gctatcggat gaggaactag aagcggtcgc aggtggaaat ctagattcac aaaattcaaa
    10321 ctggacgggc tgtgcctctg gacggtctgg ttgcgttgcc acgaatggtt gcagtattgc
    10381 agcggtaatt gggtcaggca ttgcggctac tgcaattgtc gcaggtgggg ttgctgcggc
    10441 atcagtaaca gcaggtgcac ttactgcggc atctcccctt gttgcagttg cggcaacagg
    10501 tacggctgcc gcttgtggta ttggacaagc ggcggcgagc aagtacggtt gatcgctgtc
    10561 aactggcgga taggaagggg agatcaatag acctcttgca aaagtgcctt ttgcactctt
    10621 gtcgggaaag ggagaaaggt taaaggggaa tggcactaag aaaaggcgaa aggcttgtgt
    10681 catctcattc ccagtctgaa gactgggaat gtattccaag aggctctgcc tctggtcagc
    10741 ccactggagg cggagcctcc gagaatgggt tcccagcctc caggctggga accagttagg
    10801 gcaaagctta tagcttttct tagtgccatt cggttaaagg ggaatgttaa ttctatccct
    10861 tttcccttta acccttaccc tttacccgac ttatgcaaga agtctaatat ctcctccatc
    10921 cctcccaact caaagcgaga tcgccctcaa aatttctact ctgatcgctc tacaaatacc
    10981 tgagttcgat ataagaaatt agcttgaaaa gcttgtacga tgagctttta gaccaaatga
    11041 gctaggcgct ttttctttga tttattgaga atatagtgtt tattctcatt gtgggggatt
    11101 tgttgagaac aaagtccgaa tacgtttttc agtaaaaagc tttatttatt aatgttttcg
    11161 ggcatttttt acgtcgaact cagtgacaaa taatcggagt cacaatgtct acaaccgaac
    11221 caacacccac cccagagatg aactccactg gacggatgcc aaatctggaa gcgcagttga
    11281 ttactcaagc gattcaagat cccgcatttt ggcaacgctt actgaataat cccaaagctg
    11341 tattggcaga gcagggattg aacgttcctg atgatgtgca aattaacgtc ttgcaggaaa
    11401 gtgctacgca atactacctg gtactgcctg cgctggagct tcccacggca tcgggcgaag
    11461 ttgccgagtt gtcggatgca gaactggaag cggtcgcagg gggagctaac ctggattcgc
    11521 aaaatgcaaa ctggacaggg tgtgcatcag gtcaatcggg gtgtgtggcg actaatggct
    11581 gtaacgctgc cgctcaagtg ggtttcggtg tggcatcttt tgtcggagcg acagcaacag
    11641 gtcttgcgct agcaagtgct actgctgcct tagggactcc cgcagctatg gcggcgggag
    11701 gggcagttgc aattgcttgt gctggagccg ctactgctac caagctagcg tgaatttaaa
    11761 gggacgtttg aggagtccag ttcattgcac tcgcttcagg agcgagaata acatcatcaa
    11821 caggtcagca aaatgtctac aaccgaacct acccccactt cagaaatgac cgctacaggt
    11881 cggatgccga atctagaagc gcaattgatt acccaggcga ttcaagatcc cgcatttcgg
    11941 caacgcctac tgaataatcc caaagctgta ttggcagagc agggattgaa tgttccagat
    12001 aacgtgcaaa tcaacgtgat gcaggaaagc cctacccact actacctggt tcttcccgcg
    12061 ttggaaactc ctgatgcagc gaccaccgaa ttatcggagg ctgaactgga agcggtggca
    12121 ggcggaggag gcacccttga ttcccagaat tcaaactgga cgggttgtgc gtcgggtcga
    12181 tcgggttgtg ttgccaccaa tggctgctcg gtagctgcta cggctacagt gatggttgcc
    12241 tctgcggtcg gagcggttgg agcggggata gtcaccggtg gcgtggcagc aggtctgaca
    12301 gccggactct gtattgtcgg gtcatccgct accggagtcg gaacccaagc cagataaatc
    12361 gagccaatat tttgggtaga aactaaggtt cctgactgaa tggcactaag aaaagctcga
    12421 aagcatgtgt agcctcgttc ccagcctgga ggctggaaat gtattccgag gggctgctgc
    12481 ctctggtcaa gaaagaggag gcggagccag gtatgccagg tcatctagcc tcaaaatttc
    12541 cacacagttc actttcaacc cccatcctca agaggtcaag tagagaaccc gccatgcctc
    12601 aagaaaacgt cgctcgattt tttgccgctg tgctggaagg caaagtgccg atagagccag
    12661 agcaggagtc ctgtacctct aacccagagc ggtttgtaca tctatccgaa aaatttggct
    12721 atcccttcag cctgaccgaa ttgcaagccg agattgctcg ccatattcaa aaaccccaca
    12781 tcttgcaatt attcgaggcg gcgttacacg atgaggcttt gaaacgaatg ctgaaacagg
    12841 cgagccagcc tgctcaactg caagccgcac tattaccgct gggctactca ctcaccccag
    12901 atgaactcaa tgccgtaatc tacacctgct gtcactgtgt taggggattg ttctgtgaat
    12961 gtcgagcggg cggcattggc aagcaggtat ttgagcgatc gcgcatcact tcaaccgact
    13021 tattattgcc agcgttagcg gaggactatg cgatcgcccc cgaccaaatc cgcagctttc
    13081 atcaagatgg gcatctccgg ctccgcaatg tccttacgcc tgaagaaatc gctgtctatc
    13141 gacctgcact agcggcggct gtcgatcgcc atgaccttga acaaaaagcg atggaaaaat
    13201 cggtcagtgg tcaaagtcag ggttggaagt ttgtcgaaaa tctatggaga cttgacccag
    13261 cggctcgaaa gtttacctta gcaaagcgat ttggcaaaat tgctgccgat ttacttagag
    13321 tcgatgcggt acgacttttt cgggatcagt cctacttcaa gaaacccggc ggcggcaata
    13381 ccccttggca tcaggatagc tacttcatgc ccctcgatac ccatcaagtt atcacgatgt
    13441 gggttgcgct ctctgatgtc actaccgaaa tgtcgcccat gatttttgtc tctgctgctc
    13501 accgacgggg gtatcagggg gcatcaatgc cgaacgatga atcgatggat gagtttgaac
    13561 ggaatctcga tgctaaaggc tggcaacgca tgagctacgg agcaatggtt gcaggagatg
    13621 cgagtttcca tacaggctgg actcttcata gttcacgtga aaacacgagc cagcaaactc
    13681 gtgaagctat ggtgattgtt tactatgcag atggtgcgcg agttgcaata ccgccgatgc
    13741 ctcgcaaccc caccccccca gaaaactttg cagcaatcat tcgtcaacac aatctgtcca
    13801 cctgcttacc gggcttgaaa tcaggtgatt tagcagaaac gttgatgaac ccgatcgtct
    13861 atcaacggca gccttctgaa tcactgtctg gatattaagc acatgtggct attttcttta
    13921 gaaaactcac ttcaagcgat cgcgccccac ctctcgcccc tgatcgcgcc agatgccttg
    13981 gagcgacttc aagcgatcgg tcgttgcttc cccgatgcac tgacctacag ctacggcttt
    14041 gaagcgcgtc tgcatccagc agagccaacg gtcgattttg ccattcatat cactcccaca
    14101 gagcgagata ttttagcagg cttacatccg accattaaac tacccgatgt ctttcaacaa
    14161 catccagtat ggcagcggat tcgccagttc tgtctggagt gggcagatcc gtcttctgaa
    14221 ttgcactatc aggtcaacga tctatggctg gaatttgacg cacatcagag ccaaaattca
    14281 ccagatgttc ccgttcctgg gctgtttgtc agtcccgtcc cgcctcaggg aggaatagtt
    14341 cccgactata cctggatttg gagaaaagca ctacccttac tgtgtgataa tgatatggca
    14401 gagggggtag aactcaatgt catccaatgt attcataacc ttcctacaca ggtcggaatt
    14461 tttcagtttg gattcatgtt tggcagaaag atagaagcag ttcgattctg tctgtcaggt
    14521 tcaccgattc aaatgatccc ccatctcaat cagttaggat ggcagggatc gctccaggaa
    14581 attgagcggc tctttgcctt gctctattcc tactgcgatg gcgcaatttt agacattgat
    14641 gttggctccc tgatctatcc ccgcattggt gttgaaggaa tttatatcag ccgctacctg
    14701 tcttgtgtga atggacaatg ggcatctctt ctcaatcacc tcgttgagca aaatttgtgt
    14761 gaacctttta tgcgggatgc tttgctcaag tatgccggct acacggtgaa taagcccctg
    14821 catcaacgca tctacatcag aggattgagt cacgttaaat tgctttacca acccggaaag
    14881 cccttaagca gcaaggttta ctttggcgtg atgcacaaac ccattagtgc gagtcctaca
    14941 ctttcagcag ggttacaaac cagagcagga actagcttgg cgaattctgc tgccgttgct
    15001 tctccccgcg cgactgtcac tcagagtctt caggctgcaa tcaccttcct tttaacctcc
    15061 cgcgattctc aaggctggtg gacagacttt catcttggag caggtttaag cgatgaatgg
    15121 gtgactggtt atgttgggac aaccttagcg agtgattccg cgatcgcagt cgatccccaa
    15181 gccttggacg cagctcaaac tgcctggacg ctgcttcaag ctcgccgtca ccgcatcact
    15241 ggactttggg gctttaaccg atttccaccg ggggatgcgg atagcacagg ttgggttctc
    15301 caacttgccc atgctctcgg tgagccacag tcagagcgag ttcagcaagc tcttcaatcc
    15361 ctgagagaac actggcgctc caatggcggg gtttctactt acggatcggc ggaagcgatt
    15421 cgatcgttta tctacgcggc tccagaacag agtatggagg gttggtgtgg ttctcatatc
    15481 tgtgtgagtg cggctctagc ggctcttcca gaagtacgcg accaactgct cgattatttg
    15541 cactcgactc agaacagtga gggtagctgg tctgcttatt ggtggcacga tctcgaatat
    15601 tctactgctt tagctgctga agctttagct gtaagtgatg attcctctga agcgattgcg
    15661 aacgccgttc aatgggcttt gcagcgcctt agtccaacgg gtttcattgc gactaacgat
    15721 catccattgg gatcgccttt tgcgactgct tggggtttac gattgttatt gttaggcaaa
    15781 ccagagcaaa cggaagcagc gatcgctgct gtcattcgat ggttgcttac tcagcaacag
    15841 ctagatggct catgggaatc ttccgcccgc ctgcgggttc cgttccctga tgatttagat
    15901 ccaaaccagt tcgatcgatg ggtctatcat gacaagattg aaggaagcct gaattttgat
    15961 caacatcatg tctttacaac ggcgacggtg ctacaagccc tctttaaggc gaaatctcat
    16021 ctaccattca acgccgatgc agaaagcgat cgtccattaa ctgctgtcga ttaaaccaag
    16081 tcattcaaat tcgtctttca ggaacatccc ttcaaatgat agcgatttca aagattgaac
    16141 ctgcttcctc gcgattacac gccgctgcgt tgcgtcgcat tgttgcccgt tccagtacgc
    16201 tgtatgaacg acttgaggtg gctcatgttt tacccacctc tgagccgctt gctgaagctt
    16261 tgcaacaatc ccgcatagat gcttggtgtg atgcgatcgc gaagggagat ttcgatcgat
    16321 ttcagcgctg tttgagttgg gatggaatta ccttagacca ggcaaaacaa gcaattcaga
    16381 ccgtcaccct cagagaagat gcgcctttac ctgattgggc agaaatgctg catcaggtgt
    16441 ttctgctcat gactgcacaa gcttctgagc aatctcccac ctatcgcttt ttcgatcctc
    16501 aagctccact gccgtttcaa gaactctttg ctccgtttgt attgattgct caacaagaac
    16561 tgagtagacg tacaggagcg gctgctcgca gacttacaga accagttcac gcgctgttag
    16621 agcgatcgtt gctaggtcag ttaattgatt tatcggcaca atccatcagt cttacgttta
    16681 ccagctggcg cactggtcaa caatcttcct ttggacgctt cctaagccaa atgggaagca
    16741 tatcgggtcg caatctctat cttcgctttg tccaggaaat gttgcaagga cagtttgttt
    16801 cattcttaga ggagtatgcg acgcttgccc gtctactaat aactctgaca aatctgtgga
    16861 ttgaagcgca gcaagaattt ttgcagcgtt tggatgcaga ctggttaatg attggagagc
    16921 gctttggtaa agatatttct aatgcacagg ttgtggcaat tcaagtagaa ctctccgatc
    16981 gacatcgcgg aggacgatca gtgattgctt ttcggattgg agatgatttg cctttagtct
    17041 acaagcctaa gtctctggga atcgatcgag cctacaacga tctgctgctc tggcttaacg
    17101 aacaaggttg tctgctgcca ttcaaagcag tagaggtcat cgatcgcggt gactatggct
    17161 gggtagaata tgtgttgtcc tggcactgtg ccgatgttca tcaggttaag cgtcattacc
    17221 agcgggcagg aatgttgtta tgtttaacct atgtgctgga agcaacggac tgtcaccacg
    17281 aaaatttgct tgcctgtgga gaatatccag ttctgatcga tctagaaaca ctgttgcaac
    17341 cccgtcccga tcttgagtca gccgaatatc tgcaaactgc tcatcgcatc gcgatctatc
    17401 aactgtctaa ctctgttgca cgcaccgctc tcttacctgt ttgggaaggt gaagatgatg
    17461 ccgattcttc gtttgactat agtggtctag gcagccaagt tcagcagaac cgaacctata
    17521 aaggactgca atggacagcg gtgaatacag atcaaatggc gctcacgcta caggatattg
    17581 cgatcgaacc ctcgttcagt catatgccaa tgctggatgg caaacctgcg aatctcatca
    17641 actcaattga atcagtagca gaaggcttcc agcagcttta ctatttcctg ttagaaaagc
    17701 gagagctttt actagcagaa aatagtccgc tcaaggcaat ggcaaaccaa accattcgct
    17761 tcttgttccg tcgcaccaat atctacgcta agattctcaa acagcttgcc catcccaatt
    17821 atctcaaaga tggagtcgat cgcagtattc gcctagaagt tttgaagcga tcggcagcga
    17881 tggaagccaa tcaacctaaa ttttggtcaa tgatcgatgt cgaacggcag tcgatggagc
    17941 aactcgacat tccaatgttt acgcttcagt ccgatcgaga gattctgacg ctttcttcgc
    18001 agcagcaagt tgagcaattc tttgaagggt ctgggtttga cttgatgtgg cagcgcttac
    18061 aaagcttgag tttggcagat atgtcgatgc aggtacagta catcagagct atgctgggac
    18121 tgcgcggaat tgcacctcac gaaatgagcc tgcgcgagca agatggatcg gcagaagata
    18181 gcttttctag cgaaattctt gacgatacag ccctattagc agaagcgatc gcgattactc
    18241 aacgcatcca agacagagcg attcatgctc ctgatggcag tgtaacttgg ctctctcctc
    18301 agttctctct ccaacatcaa cggttcgagc ttcaacccac taacacgagt ttgtatgatg
    18361 gtaaagttgg aattgcacta ttcctagcgg ctctagcaaa agtcactggt gaaacgtcct
    18421 acaaagagct ttgtttgcaa gcattacagg attttcagcg atcaaaggaa gcagtcttat
    18481 tttcaacgaa agaccccaat ttcaatttga atttagggct gtctgctggg ttagcaagtt
    18541 ctatgtatgg aataacctgt atcagtcggt tgctgtctga ttgcaacctt ctagagatgg
    18601 cattggacat ggtgtctcta gtagaaccgg atgtgattgc tcaggacacg tatctagata
    18661 ttttgggtgg aacaacggga attctcttga gtttaatcac gctatacgaa atgactcaag
    18721 actcggctgc actggaagct gcgatcgctt gtggtcaatc tttattagcg cggagtgtcc
    18781 ccactgaagg cggtagagct tggagaacat taagcggtcg tctgttgact gggttttctc
    18841 acggcgcagc aggaattgcc tatgccttgt tgaaacttgc acacatcaca ggcgatcgag
    18901 cctatcagct tgccgcagaa gcgggaattg cctacgagca aagctgcttc ttacccactg
    18961 tgagcaactg gtgcgatcta cgagacttct cccaattctt gctggcaacg ggcagcacgg
    19021 aagcaccgcc tctgatgtca agctggtgtc atggagcaac tggaatcggt cttggtcgat
    19081 tgggtggact gaccttgctc gataatgctg caattcgcca ggatatccag tctgctctcc
    19141 agacgaccta cgccacactg gagcaaaaac gcgaaatggt cgatcaactt tgttgtggca
    19201 gcatgggacg agttgatttc ctgattactg caagcgatcg tctaggtcaa ccagaactgc
    19261 tagcaaatgc cagagcgcaa gcatctcaag tcatccatct cgcgagaagc aagggaggat
    19321 acaccgcaga acccggactg caccaaagca tttatgttcc tgggttcttc cggggtgagg
    19381 caggcattgg ttatacgcta ttgcgtttga ttgcacctca acaactccca tcgattcttc
    19441 tcctcgaata atagcagatt cacctctcac attaaatccc tctcctgctt tggaagagag
    19501 atttaatgtg tcaattaatt atcattattg ttaatggaat agtttatttt ctggaagtcc
    19561 ctaagaggat aactttattg ctgatggggc gacaaattac cctgaaaagc ttgtgagtaa
    19621 accacattcc gcacttcaat atctgagtaa attatcgaca ctttgaaagt gtattcttaa
    19681 atccgtccca aatctgttgt tcctgaacag gaaagttctt ctgtttcaca ttcaaattaa
    19741 gcgtttgagt ggattgatcg tagttgaatt ccaagagtgc aacttgtccg acaacatcac
    19801 tcttgacgac aatttcacca ctggtatcgc ctcgatattc tagggaaccg ccattactgg
    19861 cattattttt ctttaaacaa ctaaaagctt ttggactgac gcagggaaaa ggtggagttg
    19921 agcgagataa atctttagca gaacaagtgg attgagcaat cagcggcgtt gtatgggagt
    19981 tggatgtggg attagcctca ccaatcgggg cataaaaaat cgcacaaatc atggacaaag
    20041 gaagagcaat ccatcgctga ttcatagcta aaaaatgcat agaaatctcc ttatttgact
    20101 gaaactagtt tgcgtccacg ccatgtccac ccccagcctg tttcgacttt gataatagac
    20161 gcgatcgcta atactgctat taacaatccg cccagacttt gcaaccacca gtatttggtt
    20221 gaagttccca gagcgcgcga tccttgtcgc ctgacctgat attgcaacag aattgctaac
    20281 ccggttaagc ccatctctgc aaagtgaaag aggtttgggt gcttaaggac ttgagcgatc
    20341 gctatgacaa aaccaatcca aggaatagta taaatcagta acatcaccca gatcaaaagc
    20401 agcatcaaca taacactgcg ttgtgcgcca acatatagaa tctttgtcca gccttcccac
    20461 agagcagacc agttacgata cattcgcaat gaggccagat ttgctcctag atagtgctgg
    20521 agcttaaaac cactctgttt gagcctacgg gcaaaagcaa catcttctgc tgggtaacca
    20581 gcaacggctc tgtgcattcc cacagcattg taggtagagg ctcgaaataa gagaaatggc
    20641 ccgagagcat aggtcgtttt tgtctttgga tttttgacca ctttcgagtt caagctgatc
    20701 gtcaaattga taaacatcag cggttgcact aaccactcaa ccaatgagtc acagacaatc
    20761 gtgggaatag atgtgagaaa atcaagctgt tgagcgatcg cggttgcaac aacagccgaa
    20821 atagcatcgg gttttaagcg aacatcagca tcaataaata acaaaaagtc tccattagcg
    20881 cgttctgcgc cttgctgaca cgcccagttc ttacctgtcc agaattggtc agttggtctg
    20941 ggtttcccgg tgagaatgtt caatctggga tcagctaatt gtatatttag agcttggaga
    21001 atttctgggg tgcgatcgct ggattgatcg tctacaatcc acacgtccaa ttgctttgcg
    21061 gataagcgag tgctagacac aactgattgc acacaatctg caatattttc ttcctcatta
    21121 aaagctggga taatcactga aattttaggc aattccacct cagagaaagt tccttctgag
    21181 tgggttgtga ttttaggtag ctgttttatt gcctgatgca gagaaattag ataagcagtc
    21241 aatgtcaaga tagaaactga taaaacggtg agtaaaatca aatcaacatc attgagaaac
    21301 attagatgcg gtgggtaaag tgatagttga aaaagaggca agggagtaaa gggtttcatt
    21361 ggctatgagt aagtaggtcg gcgtaaataa ttatcgttag gataaggcag ggagcaggga
    21421 gagaaagagt ttgagccttg tttatttttc ttcacatagt ttagtttttt cacacccact
    21481 tacttaataa gtaatgggta tttacttatt acttatttaa agaatgcgaa aaataacttt
    21541 tcccactgca aattttactc agaaaggatt gtgcatgaat ttttaacccc tgaaaatgta
    21601 caaaatcaac accttagctt ctgtcccctg tcctgtgcct cttccagtca gttatttctg
    21661 cttaatcacc agcaatgtaa tgtcatcaaa tattttctgc tcaccaatgt gatgacgcac
    21721 atcttcaatt actgtatatc taatttcctg agcagatttc tgccaatgct gactcacgac
    21781 ttggcataat cgctctaatc catagagttc atcgagcagg ttggctgctt ctgtaatccc
    21841 atcagtataa agaatcatcc cgtcacccga ctgtaactcc acatctagat aagaaacaaa
    21901 ttgactgatg tcttcgacta gcccgatggg gaatcctaaa tcattggttt tcactagttc
    21961 gatcgcacca tcggctcgca caatcagcac ttcctcatgc tgtccgctca atctcaatcg
    22021 accagcatga taatccatta atgtcaatgt cagattgcga tcggagttca tgcgttgcac
    22081 attttcataa atcacgcgat tgagtgtact caaaaatcgg acggcatcgg tttcctggtt
    22141 gattaacagc gttcgcacgg cagtttgcac catgagcatc aagacaccgc tttctagtcc
    22201 atgcccagtc acgtccccga tgccgatttt caccaagccc cgatcctgta gcacatcata
    22261 gtagtcgcct cccacctcat cggcaggttc catgaatcca gcaatctcta aacctggaat
    22321 ttggctgagt tctgactctt tcggcaaaat catccgctga agttggcgcg ttacatctag
    22381 ctcggtactc attcgcagat tttccgattg tagccgctga ttgagcagga taatttcctg
    22441 gtttgcctga gctaagtcag ctgtgcgatc ttcgactttt tgctccaagg tgcggtagaa
    22501 cgaagcattc tctagggcga tcgcagcttg agccgataat acattcagca ctgttaacct
    22561 tgcagaggtg aaggtatcgg ttgcgagagc gttttctaaa tagagaatac cgctaagatt
    22621 gccctggttc agaatggggg cacaaaggat cgatcgcggc tgggtctgga aaatataagg
    22681 atcaaccgta aacaacccct cctgaacggc atccctcaag actaaatttt ctcgggttcg
    22741 ttgcacatag ttaacgatcg aaatggggag ttgtgtgtct gtcagggggc gagtttctac
    22801 tataatttct atatctcgat caatgatgtg tcctgccgct tcaatccgta gttcactgct
    22861 gtggttcagg agtaagtagc ctttttgagc gcctgcattt tcgatcgcca gttgcagcag
    22921 tttttccagc aagcgatcga ggacaatctc gccagaaatt gcctgtgctg cctgaataac
    22981 ggtttccaag tccaggtctt gacctagtga gcgactgctg gttttgctag atatggagat
    23041 gccagtcatc agatccaggg tagagcgatc gcgcaactgc tgatattggg catcaatttg
    23101 ctcgacttta aatgtagctc cccaacgcag atagttatga cgagcatcta gcagatatcc
    23161 ctgcgctacc cgctcttgac ccaaattgaa atagaacttt gctgctaact cattggcgag
    23221 ggcttcttca tgggtatatt cctgagttct ggcggcttga atggcccgct cataggaacg
    23281 catggcgttg agattgtttc ctagcacccg cagccgctct gcttccacca ggtcatagcg
    23341 atgttggtaa ttttctggac agtattttgc ccattgtttt gcctggcgtt ggttgctctt
    23401 tacctggcgc aaatatcggc gacgatctgc tttggtagcg atcgcacaca atgccaaaca
    23461 cgctagggat tcatagaagt agcgattggc gtatcccggt gtcaccgggg cagattcttc
    23521 ccagggtttc gctagtctag cagcctgtag cgacccggca tagtccccag cgtagtaaag
    23581 ccacatcgct ttcgcaatgt aagtgtagaa tatgggaatt cccagccgat tgttgataaa
    23641 aactgggagc atctcatctt cattaaacgc tgaccccacc aatcgagtcg gctctgtggc
    23701 atcgccttgc aagttcaaga ccagttggtg ccagggctgc gtttgataga cgatcgcctc
    23761 ctggttaaat cgtcggaatt gggcggtgta ttcctgaaaa gcattggcta cggttgagag
    23821 gggttcaccc aaaaaaagct ggtgaatgca gtaagctgaa gccgcgatcg aggcatactc
    23881 ttgatttccc agttctagcc cttcctggta ggcattgagc aaaactgcca gggatgggcg
    23941 tagtggctct ttccagtgac gaatgcagga ttcataggca acgatagtca ttgtccggta
    24001 gatgcgatcg ttgaatcgag ccagtattcg taagctgacc tggctaaatc ggtaagcccc
    24061 gtcaatatct cccagaccta cccgtagcat caccccgtag gcaacacctt gcaccgaaga
    24121 cgagctagaa ctgccataac gaacgaccaa attcaccact cgcagcgcca gaactgccac
    24181 taacagaggt gcaacattca ccgaagccat cgctgccgat cctaatagtt gcacggctgc
    24241 tagtttgtaa ggatcggtca tgggagggag tgattctagt tgcgctagcg aaagcctgcc
    24301 cacaatccag aagcgggtgc ggagcaattc taatcccact cgcagccgat taggattccg
    24361 gggcagcggt tcgcctaagc gcgccatcgc actcacaatg gtgtccaagg ctgcctgtaa
    24421 attattttga gccgtgtagg ctcccactct gacctgatag gctttgacgc aatcaagaat
    24481 ggttttggca tcgtgcaaaa tccgttctac cagacgctct gtctctgcaa aatctccgtt
    24541 taaataagcc gattctgcgg cttcttcatg gagtgcaaga gtcaatgcat actgccgttg
    24601 ccagctttgc tctcctagta aatcaatgcc agtcagcaag tagcggatgg cagtttcgta
    24661 ggcggcggag tctttggctt tcttaccagc gatcagattc agtgtcgcca attcattccg
    24721 ttgtgccgag tcggtaatca ggttgatgcc aatattgagt tgattgacga tatcaaaaat
    24781 tcgctcttct cgcttttctg ggggggtgtg gtcgagtagc agttgtccga tctgacggtg
    24841 aatggtctgc ttttcggcat ctggaattag ggaataagca acctgttgga cgcgatcgtg
    24901 gaggaacttg aacaccacaa ctaaatctgc ggaagtttgc tcctctatac tggtaaactt
    24961 gtaattctct cccagtggta ggatcaatcc ttcttgcacc ccttgccaaa ggtcgcgtgc
    25021 taatgtagct ggagaagatt cagagatgat tgacagggtt tgagaatcaa actgattccc
    25081 aatacacgca gctagtttca gtgctcgttg ggtttgggga ggcatttttt gcatcttgcc
    25141 cgtcatcaac tctacaacgt tgtcgggtac tggagccgct cgcagttgca ctaaatccca
    25201 ttgccagcgc cccaattgct catcgaagtt gagcaatcca tcttcgtaca gggacttgag
    25261 aaacctattg gtaaagaatg gattgccatc ggtgacttgc aggagcaatt ctgctagggg
    25321 agttgcctgt tcggcagtac agttaaatgt gtcaaggatg agttgggtaa tgtttgtcag
    25381 tgtcaggggc gaaagttcaa tctggctgac gatgaccttg gcttggcgaa tttcctcgat
    25441 cgccaccatc aagggatgaa ctggactcac ttcattgctg cgatatgccc ccaccagaaa
    25501 caagaactga ctatcagcag atgtcatcaa ccgattaatc aacttgagag atgcagaatc
    25561 tacccactgt aagtcatcca gaaaaattac taggggatgt tctgactgag taaatacctt
    25621 aatgaaattt tggaatacta agttgaaacg gttttgcgcc tctctcgatc cgagttccgg
    25681 cggtgcaatc tgtttgccaa taatcagttc cacctctgga atcacatcaa tcaccacctg
    25741 accattgttt cccaaggtgt tgagtagttg cgatcgccag cgatcaattt gtgctgggct
    25801 ttctgtcagc agttggcgca gtagttcttg aaatgcctga attaaaccag agtagggaat
    25861 gttgcgctga aactgatcgt atttccccga aatgaaatat ccttttttgc gtgtaatcgg
    25921 tttatgaatt tcattcacta gagccgactt gccaatgcca gaatatccag caactaacat
    25981 gagttcgctt ttgtgattcc cgccagtgac aacgcgatcg aatcctgtta gcagtgtttc
    26041 cacttctagc tcgcggccat agagcttttg gggaatctga aacttccctg atgcatcttc
    26101 ttgccccaat gtaaaggatg caatttgatt tccctgccga atttgctgcc aacactgttg
    26161 caaatcggct ctaatcccat aggcgctttg atagcgatcc tcggcattct tggccagcag
    26221 ttttaaaaca atttgagaca ccatcacggg aatctcaggg tgaattagat ggggcggctc
    26281 cggttgtttt gccagatgac agtggatcaa ttccattgcg tcggtgacgg cgaacaccgg
    26341 agttcccgtc agcaattcat agaaggttgc ccctaaggag taaaaatcgg tgcgatagtc
    26401 tagggtacgg ttcatccgac ctgtttgctc tggggataag tagagcaatg ttccttctaa
    26461 aacactgggg ctgctcatag agggattttc ccgcgatagc actgtcgcat tgccaaaatc
    26521 aatcagcttt acttgtttgg aaattggatg caacagaata ttggcggggg taatatcttt
    26581 gtgaatcaca ttggcagcat gaacctgacc gataatttcc gttaaggcga tcgctagttc
    26641 taaaaattcc tccagatcaa ggcggcgctg ttgtaagact tgatacaacg attcgccgcc
    26701 aaaatcttct aataccagag ccaacccatg ccgatatttg atcaaatcat aagcagccgc
    26761 cacgcctgcg ccatgcagcc gattgatgat gtcatactcc aggcgatacc tgctcaattc
    26821 ttccaggctg ggatattctg cctgcatcac cttcaaaatc acagattgcg gttgatgatt
    26881 gctgcgcccc cgataaacta gcgaacgact cccctcatag agggttgaaa gcacttcata
    26941 acctgcgatc gtgaccatag agcatagcta cattaaaaca agaattgcag tcggagaaca
    27001 ttaccaaaga cagtaggatt gtcgctaaag ttattggcgt taaaggtggc gaaaaaagtc
    27061 ggtacaattg tcagattact actaattggg taagcatagg tcgcttccag atcaaattcc
    27121 gtgccaccgt tgccattgcc tgccacaaag aattgacgac ctgacaaaat attaaacggc
    27181 acgaccagcg atagggttcc tagcgctcct ttccgtccca agtctggtag agctgcacct
    27241 aattgaaacg cttgtacatt ggcagagcca ctctgaatta gggggttgac tggattgata
    27301 cctgcttggg tataggaata gcgcccaaat agggcgaacg ttggggcgat tttccagtcg
    27361 aaattaaaga cgaagttgtc tgaatcaata tcatttaagc tgcccccaaa tccatcatct
    27421 accacacctc tgagggagtt agtcaggaaa aaagggaagt tgggctgaga gggtggtgag
    27481 gcgggaggag cctgactgtg gctgcgcgtg tacaggaagc ggagcgttgt ttgcggggag
    27541 ggggagtaag caagttccgc cagcaacgaa taagagccgt taaacagtcc gcgctctggg
    27601 ttagcagcac catctccacc aaagtactgt agtgaggcat cattgcggtt caggtatcct
    27661 gcttgaaacg ccagctttga gctgatctgc cagttgagaa ttgctcctgc accagacaag
    27721 ccactgtttg ccaaggtact ttgataggaa ttgagaccac tagctccatt gacaacgttt
    27781 gtgtaggggt ttacatcaaa gtgacgaaat gtcaagatgc gcggcccgac tacagcattg
    27841 actgaattgc tgataggaaa ttgatatttc aactcaaata ggccgatact attgggtgcg
    27901 aggggattga ccggattaga atcagcgtag ggtacaccaa aggtactggc aaagccagct
    27961 gaactgtagg tactgctggg cggactgcca ttcccggcgg ccaaaattgt cgtgagagta
    28021 tctcgaccgc taaatgaaga cgacaaaatc agataggtcg attgactgaa ggttgttgag
    28081 gcagtgcggc tagttgtggt gactattggc tctaatttac cagtggcagg attgggagat
    28141 cgcagcgcta gtctagcagc gggaagtgag ttagggattg gaacaccttc tgctttcaca
    28201 tctccactgg caaatgcctg actgacattg aaagaagaca gaacattaag gcgggttgtt
    28261 gcagaaaact gttgtgcctt gagcgtagca gtacgagtct ctaagctgtc tactcgacct
    28321 cgcagcgtcc ccagttctgt ggcgaactct gcttgcagtt tttgcaacgt tgctaagtct
    28381 tcttttgtca ccagagcggt tgttgcagtg gcaatcaatt cgttcacgcg atcgaggcag
    28441 gcattgatcc ctgccgcaaa ttcatagcgg gtcagcgatc gattgccacg ataagtgttg
    28501 tttgggtatc ctgcaataca gccgtagcgc tcaaccaggg attgtagtgc ctgaaatgcc
    28561 cagtctgtgg gcttgacatc ggtcaattgg gaaactgaag tcacttgagt cagggcatcc
    28621 tctgagggat tcaacggttc atccaatctg gtgggtgatg caccatcttc gactcttggg
    28681 ggtgctgcta accccttgga ggtggatagg aggatgactg ccaacaccgc agatttcagc
    28741 catgctcgac ccattctgtt tgttacaatc tcacttatca acaatttaca ctcctcaaaa
    28801 cttaaatttt ggaaattagc ggtaatccct gatcaaaaga ggcaggcgag aaagattctg
    28861 taatttccct gccataaggg ttcagagcaa ccaaatttat gatatttttg tttgatttct
    28921 gatgggttca accccaacca ttaaaacttt acaatttata gttcaacagg ttaaaaatat
    28981 tctcagcaat tgacaattaa atttttgcga cagtgccttc aggtacaggc aatattttta
    29041 gctgtctttg ttctcgtatc ccttgctccc aatacggttc ggttaaggtt ttttgatgaa
    29101 aattttagat cgcaaagacg cgatgaatcg ccgtcaagac aaaagactga ttattgtaga
    29161 gactgtgatt tatcgcgtct cttgctttca tcaaaccgta ttgctctcac tcgcctcagc
    29221 tagacatgat atgagaagct taactcttcc ctcgatttca gatataactc ttccctcgat
    29281 ttcagatata aactaacggg ggagggatcg ataagaacta ggggtatttt tgtgcgcctg
    29341 ctgacaacag tggcagcttt acgctgctat ttaactaaac gctgcttaga aaacaaacag
    29401 atagcggtta ctgaggatct gaaactagat gatattactg gctggtatca g
//
