LOCUS       NZ_CP054919            21404 bp    DNA     linear   CON 31-JUL-2024
DEFINITION  Kitasatospora sp. NA04385 chromosome, complete genome.
ACCESSION   NZ_CP054919
VERSION     NZ_CP054919.1
KEYWORDS    RefSeq.
SOURCE      Kitasatospora sp. NA04385
  ORGANISM  Kitasatospora sp. NA04385
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Kitasatospora.
REFERENCE   1  (bases 1 to 8400742)
  AUTHORS   Zhang,B., Shi,J. and Ge,H.
  TITLE     Genome mining for natural products
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8400742)
  AUTHORS   Zhang,B., Shi,J. and Ge,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUN-2020) Institute of Functional Biomolecules, State
            Key Laboratory of Pharmaceutical Biotechnology, Nanjing University,
            No.163 Xianlin Avenue, Nanjing, Jiangsu 210046, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. v2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013364235.1-RS_2024_07_31
            Annotation Date                   :: 07/31/2024 08:11:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,532
            CDSs (total)                      :: 7,423
            Genes (coding)                    :: 7,206
            CDSs (with protein)               :: 7,206
            Genes (RNA)                       :: 109
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 218
            CDSs (without protein)            :: 217
            Pseudo Genes (ambiguous residues) :: 0 of 218
            Pseudo Genes (frameshifted)       :: 81 of 218
            Pseudo Genes (incomplete)         :: 153 of 218
            Pseudo Genes (internal stop)      :: 9 of 218
            Pseudo Genes (multiple problems)  :: 25 of 218
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:10:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7571017
            Orig. end                         :: 7592421
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054919.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21404
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="30"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21404
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21404
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11404](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11404
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(82..97)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.48"
                     /tool="antismash"
     gene            307..4119
                     /locus_tag="HUT16_RS39495"
                     /old_locus_tag="HUT16_33485"
     CDS             307..4119
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024487.4"
                     /locus_tag="HUT16_RS39495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_33485"
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_176191758.1"
                     /transl_table=11
                     /translation="MGSGHAQRARQQALLECWRAIELFSPPSIPQKPRRRAARSGRSEE
                     YLVDLAPAAGRPAPRLPWDADHPDTGAARAPRGRMWRHEVYGGVFALDLLRRTMAAALP
                     AGTDPDPGVPEEELRLPGESAVFALILDEDGRPVEDTSVVSACAWATGRLFDPGPGARD
                     WLTGFTDLDVAFGTAVADLTTTAVPYAPAAATAAAATTAAASAATAAAGGGGWRQLLAE
                     ILGGAAVGAVGALFGEVAGAAVQGATEPLLRRAADWAAERAPAGAAPAPDRPGPGPGPG
                     PETGPGTRPGTGSETETGTGPETATEAEAEAGDEPEGAAARPVCLADLVALTAQIAHLC
                     GVRELLRPDSIRVYSRLVPRPTGRTRNAVPAPFLNSLLPPDLERVRAALAAADGKGSGP
                     ALTAYLTEWDAVDPAARTDLRADRTAVLDGVAPELVPDGRWPTTPRHPLALSQQYAVNR
                     MLADRAGTDGGMFSVNGPPGTGKTTMLRDLVAALVVERAAVLAEFDQPWRAFTGRAWQG
                     LDREGRNRRYVARLDPRLTGFEIVVTSSNNGAVENVTAELPALEALDETWRDGPDHFSD
                     LASALLRGAPAWGLVAAVLGNRKNRREFGERFWWGRLPEDETAARDRAGQPPLRGMQAV
                     LRDWIPPKSTVQGRRSAEPAQPVPSWPDAVAAFRTARAEVERLRRERAATAAELAATDS
                     PQALHGLAVLAGAAHRAEAEAHRHTEQVERAHRDAAGARAVTTAAAELLRTVEVHDRRA
                     RDELAAADATADATRTVAAELAAARHRQEQAEARAADAAAALDRASAAVSSARRAHAEA
                     AAAAETRRARLRALADEGLPTLPLGWAALDEAAQELGAPWSGPDWSAARSELFLRALDL
                     HRAFVAGAAQRVLGNLQVLMELMAGTSGPVPDEQVEQAWQTLFLLVPVVSTTFSSVGSM
                     FARLGAGSLGWVLVDEAGQATPQAAVGALWRARRAVLVGDPLQLEPVVTMPLALQRRLL
                     RAYGVDERWLPSTTSAQVVADRTNRHGTYLPAPEPGGDPVWVGSPLRVHRRCEEPMFGV
                     SNAVAYDGLMVHGTAPGAFPDRQHDGRLPSRWLDTPDPDRPPGVPWGERDERAFEFVLD
                     RLAEHGVGVDRLRVITPFRAVVNACRRVCRTRGWTPEQLDERCATVHRAQGKEADVVIL
                     VLGTGLPGARAWAARTPHLLNVAASRAKRRLYVIGERGLWSPLPHFDVLGALLPVFDHH
                     RDRDTWGGTGRPADPSADPSGGPSADPPGGPPVDPPGGPPGGSVA"
     gene            4300..5553
                     /locus_tag="HUT16_RS33490"
                     /old_locus_tag="HUT16_33490"
     CDS             4300..5553
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387443.1"
                     /locus_tag="HUT16_RS33490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_33490"
                     /product="MFS transporter"
                     /protein_id="WP_176191759.1"
                     /transl_table=11
                     /translation="MVGRRRLGRPFGWLWASYAVSAYGSGLGFGALPLIAVLVLHAGPA
                     QVAVLSAVGPAVGALIALPLAPRTETRRKRPVMIGADLVRCAAMASVPAAYALGRLGFV
                     QLLVVSAVVAAAKIAFNAASGAYLKTLVPAQDLLVANSRFESTNWSSIAIGPPLGGAAI
                     GVLGPVVTVLADALSYLLSALGITAIRDREEAPRTSARSPLRADGLLEGWRHILGHPVL
                     RALYLNNLLVSGLIMATEPLLAVLLLRQLGFPAWQYALAFAAPCLGGLLGSRLAPRVVA
                     RYGRRAVFRTVGTLRAVWLPGLALVRPGVPGLVTVMAVELAIIVHMSLYTPVLATYRLE
                     HTPAHLVTRTLTAWSVGQQAAIATLTALGGLLAHFTGPRTALAAAGVLILATPLLLPRN
                     TRHQHAPHPEPEPSRSRA"
     gene            5724..6335
                     /locus_tag="HUT16_RS33495"
                     /old_locus_tag="HUT16_33495"
     CDS             5724..6335
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387442.1"
                     /locus_tag="HUT16_RS33495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_33495"
                     /product="cysteine hydrolase family protein"
                     /protein_id="WP_254898111.1"
                     /transl_table=11
                     /translation="MNPAPASDTAPDPIRTALLVLDYQPATLAFVPEGEDRDSLLGRVA
                     GAVADVRAHGGTIAHVRAAFTEADWDAVPDANKSFAPLARHRAMHHEDPATAPHEQLAP
                     RDGDITVRKTRFGAMSTTDLDRQLRARGITTLVVSGLSTGGAVLSTVLDAADLDYRLYV
                     LSDGVADPDPEVHDILLRKVLPTRAHVIDTAALHALLRMA"
     gene            6360..6548
                     /locus_tag="HUT16_RS33500"
                     /old_locus_tag="HUT16_33500"
     CDS             6360..6548
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUT16_RS33500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUT16_33500"
                     /product="hypothetical protein"
                     /protein_id="WP_176191761.1"
                     /transl_table=11
                     /translation="MELTEHRPVAPRMLLARRIERWFVLERPVFIPAGCRFWTERDALV
                     VEHPTGERRRYAGFVCR"
     misc_feature    complement(6586..6596)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    6593..6606
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.73"
                     /tool="antismash"
     misc_feature    6649..6662
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     misc_feature    6777..6794
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.86"
                     /tool="antismash"
     misc_feature    complement(6873..6887)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 30.11"
                     /tool="antismash"
     misc_feature    6874..6888
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.65"
                     /tool="antismash"
     gene            6993..9440
                     /locus_tag="HUT16_RS33505"
                     /old_locus_tag="HUT16_33505"
     CDS             6993..9440
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140069.1"
                     /locus_tag="HUT16_RS33505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_33505"
                     /product="glycoside hydrolase family 9 protein"
                     /protein_id="WP_254898112.1"
                     /transl_table=11
                     /translation="MPVRSVPASSGPGPSRSVRRTVLGLVAAGALAAGALLPLHVAAAD
                     TAVAAPAFNYGEALQKSLLFYEAQQSGHLPATNRVSWRGDSALDDGKDVGLDLTGGWYD
                     AGDHVKFGLPMAASTTMLAWGGIAEKQGYTASGQMPYLKNNLRFVDDYLIKAHPAPNVL
                     YGQVGSGSADHAWWGPAEVLPMARPAYKIDASCPGSDLAGETAAALASSSMVFADSDPT
                     YAATLLTHAKQLYTFADTYRGKYSDCIKDAQGYYNSWSGYNDELVWGAIWLYKATGDSS
                     YLAKAESYYANLSTEPQSTTKSYKWTIAWDDKSYGAYVLLAQLTGKQQYVDDANRWLDW
                     WTVGVNGSQVKYSPGGEAVLDSWGSLRYAANTSFVALVYSDTLTGDPTRKARYHDFAVR
                     QIDYALGDNPRKSSYLIGYGANSPKNPHHRTAHGSWTDQLTSPVNSRHTLIGALVGGPS
                     SADDSYTDDRSNYVNNEVATDYNAAFTGALARLYGEYGGSPLAVFPPKETPDGPEMSVQ
                     ASVNAAGTNFTEIKAYLINKSAWPARALKNASLRYYFTLEPGVSPSHITLTTNYNQCGA
                     VSGPTLYSGSTYYVTVDCSNTVIAPAGQSAYRKEVQFRIASSGAWDPTNDWSYQGISLV
                     PGSTPVDAPDIRLLDGGVPQWGAEPGSGTGSSPSPSPSPSASTSASPSPSPSPSASSSP
                     SPSPSPSASGSASPQPVSGCAVTYKVGSSWGTGFTADVTVRNTGSGTVSSWKLGWTYRG
                     NEVISNAWNAQVVQSGAAVTVTDAGWNGTLAPGGTASFGFQATGTPAALPAFTLNGTAC
                     TNA"
     gene            10001..11404
                     /locus_tag="HUT16_RS33510"
                     /old_locus_tag="HUT16_33510"
     CDS             10001..11404
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240846.1"
                     /locus_tag="HUT16_RS33510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_33510"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_176191762.1"
                     /sec_met_domain="T1TS (E-value: 6.2e-65, bitscore: 219.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDPGLSSPLQAPPAPAAAPSSPSGPPSDPFASALTAALAAATAA
                     AGSAAGSAGSTGSAAPAESAEASSAPVEIVEAAPVAVSGSGLQRILRGPSGLGTKGLFL
                     VTEPPQPAAVEQAVQGLVERLAEPVAEAAAPVVDVPVEGVPVPGLYFHPIPEPDPARVA
                     EVSRRIKEWAVDEVDLFPDEWEGQFDGFSVGRYMVACHPDAPTVDHVMLATRLMVAENA
                     VDDCYCEDHGGSPVGLGGRLLLAHTALDPLHTTAEYAPGWAESLGADAPRRAYRSAMRY
                     FTEAASASQADRFRHDMARLHLGYLAEAAWSETDHVPEVWEYLAMRQFNNFRPCPTITD
                     SVGGYELPADLHAMPETQRVIALAGNATTIVNDLYSYTKELASPGRHLNLPVVISEREG
                     RSDRDGYLKAVEVHNELMHAFETEAAALAASCPAPPLLRFLRGVAAWVDGNHHWHQTNT
                     YRYSLPDFW"
     gene            11490..12368
                     /locus_tag="HUT16_RS33515"
                     /old_locus_tag="HUT16_33515"
     CDS             11490..12368
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965304.1"
                     /locus_tag="HUT16_RS33515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_33515"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_176191763.1"
                     /transl_table=11
                     /translation="MTSTELSTSATAFVPAPATAYQGDIARYWNNEARPVNLRLGDVDG
                     LYHHHYGIGAIDTGALGTPEDSEYEKKLIAELHRLESAQAEVLLDHLGPIAPGDTLMDA
                     GCGRGGSMVMAHQRFGCKVEGVTLSSTQAEFGNRRVQELGIADHVRSRVCNMLDTPFAN
                     GQMSGSWNNESSMYVDLHDLFAEHSRVLKVGGRYVTITGCWNPRYGQPSKWVSQINAHF
                     ECNIHSRREYLRAMADNRLVPQAVIDLTPDTLPYWELRATSSLVTGIEEAFIESYKDGS
                     FQYVLIAADRV"
     gene            complement(12503..14797)
                     /locus_tag="HUT16_RS33520"
                     /old_locus_tag="HUT16_33520"
     CDS             complement(12503..14797)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025791.4"
                     /locus_tag="HUT16_RS33520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_33520"
                     /product="SUKH-4 family immunity protein"
                     /protein_id="WP_176191764.1"
                     /transl_table=11
                     /translation="MSERAQEPEQGVDGSPDGNGRAGASVPDTVRNAAQDAAQDAVRNA
                     VRDAVRDATDWLRETGPGLLYVCGAAGSGKTSVLAALAERFPEALLVDTAGRSGDAVAR
                     GLIEGAGVRSRGAQLDFGGLVRALRKERKPRVVLLANPQLAGSLASGGERELLRWMVRW
                     LSIGASEGRLRLVVEQDRVPVFADPEPTRYRRTVLTLPGGGAAAELRAFEAAVPAGARA
                     ALVALACAEHHRVPVEGWAALCRAAGVTDVADGQLASWAEELPWLVADGTGVGFASPAL
                     AGALREAAGDLTALHGRMTDALLGAAGTAALPEWAARALPGHAAAAGRFDALLADARAL
                     ARIPQDALLEGVRGGYPDGVAPGTDAAALHHLGGYGLAGVPHGHWVAHLALDAFTRGRP
                     ERARLLAESCPEPLLFHPVWADWRPPGDYDRLPATRHESDLENLTAVEVDGRPAVLLED
                     ERGVRFVRDAGTGEVLAGPLPGDAEPDTGPDAGLRTAPGAALVLRQKWHRSEVHDADGK
                     PLGVFHHPEAGYAVAVGGLVVLADSRGAYAVELDAGLLRAGPEQRLVPVIGGPGRVLPR
                     PFDPAAVADLAGLLARAFGPGQVHRLRADELPAGVVHGPTRRLLTEVGVPSVPDLVGLC
                     LEPTGPDAFAPHPWESVPENEQPAGSGPFLSLGRWMGARLLLDGATGRVLRMLPAGSPD
                     HAHPRAPLAGSSLGSFLTMVALQQHYLAVYRTGGPDRHGVLGELELRLAGVDPGAAGAD
                     CWQYVSEPFNW"
     gene            complement(14845..16329)
                     /locus_tag="HUT16_RS33525"
                     /old_locus_tag="HUT16_33525"
     CDS             complement(14845..16329)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025791.4"
                     /locus_tag="HUT16_RS33525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_33525"
                     /product="SUKH-4 family immunity protein"
                     /protein_id="WP_176191765.1"
                     /transl_table=11
                     /translation="MTTGPEPTPRPDRSFLPAELPALIEDPLFLAQVDRTRLLAGMAEC
                     WPDGVPAGTLAEDVHHLDRLGVRPPAERHGEWLSWLHLLLVSHGRADDAAVLADAGYRL
                     PWRTVWSRWVPPGARAARPTGGGRVVALRVVEHEDAPVVSVHEQYVLARLDRMEPDDED
                     GYYEYAVDLADGAVLAGPQLFRPFEADDLPDPYEPVLPEDLPELGEAVLNGPDGWDDET
                     AGLPAAPEQVEHAVRVDRLAVFGGGWGCYAVELHTGGDPDESEGGDEDRDEDTDGDGNE
                     GAATGPFVDGSAPAVTALAPAGLPPEAREPDREWLARYYGADALWTSDPADLPAGLRHE
                     PTRRFLTEVGFPAVRHPLLDFSSETLAEKGLSELRTADLHSPEDPDFAGLGEHAYLIAT
                     DNDGLTLITVDGESGRVSRYSTERWEGDYYGGVMASSVERFAALLRLYATYYRGADEAA
                     LADSGRQLRDWALELDPVVARSDFWTEVFQDREDFV"
     misc_feature    complement(17032..17045)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     misc_feature    17353..17373
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.27"
                     /tool="antismash"
     misc_feature    complement(17563..17577)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 21.84"
                     /tool="antismash"
     misc_feature    complement(18244..18258)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 20.8"
                     /tool="antismash"
     misc_feature    complement(18970..18984)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
ORIGIN
        1 gtaccgtgga gcctcacccg taggacgggt cggcggggcc gtgacaccct gccgacccac
       61 cgggtggccg cgcccttccg gtccaccagc tggtccaccg cctcccgccg ttcaccatcc
      121 gtcgcccgtc gcccgtcgcc cgttgctccg gtgccccccg gccgcttccc gcacggcccc
      181 gcaggctctc ccgggaggtc tccggaacgg ccggagggcc ggttccccgc accggcggtc
      241 gggtagattc cgagggcacc catcggtgtg cgaagtttcg gggcgaggcc cggtgagggg
      301 cggtcgatgg gcagcggaca cgcgcaacgg gcccggcagc aggcgctgtt ggagtgctgg
      361 cgggcgatcg aactgttcag cccgccgagc atcccgcaga aaccgcgccg ccgcgccgcc
      421 cggagcggcc gctccgagga gtacctggtc gacctcgcac cggcggccgg acggcccgcc
      481 ccgcgcctgc cctgggacgc cgaccacccc gacaccggcg ccgcccgggc cccgcgcggc
      541 cggatgtggc gccacgaggt ctacggcggg gtgttcgcgc tcgacctgct gcgccggacg
      601 atggcggccg ccctgcccgc cggcaccgac ccggacccgg gcgtaccgga ggaggaactg
      661 cggctgccgg gggagagcgc cgtgttcgcc ctgatcctcg acgaggacgg ccgaccggtc
      721 gaggacacct cggtggtctc cgcctgcgcc tgggcgaccg gccgactgtt cgaccccggc
      781 ccgggcgccc gggactggct gaccggcttc accgacctgg acgtcgcgtt cggcacggcg
      841 gtcgcggacc tcaccaccac cgccgtgccc tacgccccgg ccgctgccac tgccgctgcc
      901 gctaccactg ccgctgcttc cgccgccact gcggcggccg ggggcggcgg ctggcgacag
      961 ttgctggccg agatcctcgg cggcgcggcg gtcggcgccg tcggcgcgct gttcggcgag
     1021 gtcgccggag ccgccgtcca gggcgcgacc gaacccctgc tgcgccgcgc cgccgactgg
     1081 gccgccgaac gggcccccgc cggtgcagcc cccgcaccgg accgacccgg gcccgggccc
     1141 gggcccgggc ccgaaaccgg acccgggacc aggcccggaa ccgggtccga aaccgagacc
     1201 gggaccggac ccgaaaccgc taccgaggcc gaggccgagg cgggggacga gcccgaaggc
     1261 gccgccgccc gcccggtctg cctcgccgac ctggtcgcgc tgaccgcgca gatcgcccac
     1321 ctgtgcgggg tgcgggagct gctgcgtccc gactcgatcc gggtgtacag caggctggtg
     1381 ccccggccga ccggccggac caggaacgcc gtccccgcgc cgttcctgaa cagcctgctg
     1441 ccgcccgacc tggaacgcgt ccgcgcagct ctagccgccg ccgacggcaa ggggagcggc
     1501 ccggccctga cggcgtacct gacggagtgg gacgcggtcg acccggccgc ccggaccgac
     1561 ctgcgggcgg accgcaccgc cgtcctggac ggcgtcgccc cggaactcgt cccggacggc
     1621 aggtggccga ccaccccgcg ccacccgctg gcgctgagcc agcagtacgc ggtgaaccgg
     1681 atgctggccg accgggcggg caccgacggc gggatgttct ccgtcaacgg cccgcccggc
     1741 accgggaaga ccaccatgct gcgcgacctg gtcgccgcgc tggtggtcga acgggccgcc
     1801 gtgctggccg agttcgacca gccgtggcgg gcgttcaccg gccgcgcctg gcagggcctg
     1861 gaccgggagg gccgcaaccg ccgctacgtc gccaggctcg acccccggct gaccgggttc
     1921 gagatcgtgg tgacctcctc caacaacggc gcggtggaga acgtcaccgc cgaactcccg
     1981 gccctggaag ccctggacga gacctggcgc gacggccccg accacttctc cgacctcgcc
     2041 tccgcactgc tccgcggcgc ccccgcctgg ggcctggtcg ccgcggtgct cggcaaccgg
     2101 aagaaccgcc gggagttcgg cgaacgcttc tggtggggcc ggctccccga ggacgagacc
     2161 gccgcccgcg accgcgccgg acagccgccg ctgcgcggca tgcaggcggt cctgcgggac
     2221 tggatcccgc ccaagtccac tgtccagggc aggcgttcgg ccgaaccggc gcaacccgta
     2281 ccgtcctggc cggacgccgt cgccgcgttc cgcaccgccc gcgccgaggt cgaacggcta
     2341 cgccgcgaac gggccgcgac ggccgccgaa ctcgcggcca ccgactcccc gcaggccctg
     2401 cacggcctgg ccgtcctcgc cggagccgcc caccgggccg aggccgaggc gcaccggcac
     2461 accgagcagg tcgaacgggc ccaccgggac gccgccggcg cccgggccgt caccaccgcc
     2521 gccgccgaac tgctgcgcac cgtggaggtc cacgaccggc gggcccgcga cgaactggcc
     2581 gccgccgacg ccaccgccga cgccacccgg accgtcgccg ccgaactggc cgccgcccgg
     2641 caccggcagg agcaggccga ggcccgcgcg gccgacgccg cggccgccct ggaccgcgcg
     2701 agcgccgccg tctcctccgc ccgccgggcg cacgccgagg ccgccgccgc ggcggagacc
     2761 cgccgcgccc ggctgcgcgc cctcgcggac gaggggctgc ccaccctgcc gctgggctgg
     2821 gccgcgctcg acgaggccgc ccaggaactc ggcgccccct ggtccgggcc cgactggtcg
     2881 gccgcccgca gcgaactctt cctgcgcgcc ctggacctgc accgcgcgtt cgtcgccgga
     2941 gccgcccaac gcgtcctcgg caacctgcag gtgctgatgg agctgatggc cggcaccagc
     3001 ggccccgtcc ccgacgagca ggtcgaacag gcctggcaga cgctcttcct cctcgtcccg
     3061 gtggtctcca ctaccttctc ctcggtgggc agcatgttcg cccggctcgg cgcgggcagc
     3121 ctcggctggg tcctggtcga cgaggccggc caggccaccc cgcaggccgc cgtcggcgcc
     3181 ctgtggcggg cccgccgcgc cgtcctggtc ggcgacccgc tccagctcga accggtcgtc
     3241 accatgccgc tcgccctgca acgccgactg ctgcgcgcct acggcgtgga cgagcgctgg
     3301 ctgccctcca ccacctccgc ccaggtcgtc gccgaccgca ccaaccgcca cggcacctac
     3361 ctgcccgcgc ccgaacccgg cggtgacccg gtctgggtgg gctccccgct gcgggtccac
     3421 cgccgttgtg aggaaccgat gttcggtgtc agcaacgcgg tcgcctacga cggcctgatg
     3481 gtccacggca cggcccccgg cgccttcccc gaccggcagc acgacgggcg gctgcccagc
     3541 cgctggctcg acacccccga cccggaccgg ccgcccggcg tcccctgggg cgaacgggac
     3601 gagcgcgcct tcgagttcgt cctcgaccgg ctggcggagc acggcgtcgg cgtcgaccgc
     3661 ctgcgcgtca tcaccccgtt ccgggcggtc gtcaacgcct gccgccgggt ctgccgcacc
     3721 cgcggctgga cgcccgaaca gctcgacgaa cgctgcgcca ccgtccaccg cgcccagggc
     3781 aaggaggccg acgtggtgat cctcgtcctc ggcaccggcc tgcccggagc ccgcgcctgg
     3841 gccgcccgca ccccgcacct gctcaacgtc gccgcgagcc gcgccaaacg ccgcctgtac
     3901 gtcatcggcg aacgcggcct gtggtccccg ctgccgcact tcgacgtcct cggcgccctg
     3961 ctgccggtct tcgaccacca ccgcgaccgc gacacctggg gcggcaccgg ccgccccgcc
     4021 gatccgtccg ccgatccgtc cggtggtccg tccgccgatc cgcccggtgg tccgcccgtc
     4081 gatccgcccg gtggtccgcc cggcggttcc gtggcgtgaa gcccgccgtc cgcgacggtt
     4141 cctcctgctg ctcgacaacc ccgaccggcc tcgacggaca accagtggtt gtggcgcacc
     4201 ggtaggtcga ttgtttgacc tgccggtatc cgggccggtt acctctcacc ggtcaacgtc
     4261 ggtttgtccg agcggcacct cgaggggagc acgtcgagca tggtgggcag gagacggctg
     4321 ggccgtccgt tcggctggct gtgggcctcg tacgcggtga gcgcgtacgg gtccgggctg
     4381 gggttcgggg cgctgccgct gatcgcggtc ctggtgctgc acgccgggcc cgcccaggtg
     4441 gcggtgctct cggcagtggg cccggcggtg ggggcgctga tcgcactgcc gctggcgccc
     4501 cggacggaga cgcgccgcaa acggccggtg atgatcggcg cggacctggt ccggtgcgcg
     4561 gcgatggcct ccgtcccggc cgcgtacgcc ctcggccggc tcggcttcgt ccagttgctc
     4621 gtggtctcgg ccgtggtcgc cgccgccaag atcgccttca acgcggccag cggcgcctac
     4681 ctcaaaacgc tcgtcccggc gcaggaccta ctggtggcca actcccgctt cgaatccacc
     4741 aactggagct ccatcgcgat cggcccgccg ctcggcgggg cggcgatcgg cgtcctcggg
     4801 ccggtggtca ccgtgctcgc cgacgcgctc agctacctgc tctccgcgct cggcatcacc
     4861 gcgatccgcg accgggagga ggcaccgcgg acgtccgccc gcagcccgct ccgggcggac
     4921 gggctgctgg agggctggcg gcacatcctg ggccaccccg tgctgcgtgc gctctacctc
     4981 aacaacctgc tggtctccgg cctgatcatg gccaccgaac cgctgctggc cgtcctgctg
     5041 ctgcgccaac tcggcttccc cgcctggcag tacgccctcg ccttcgccgc gccctgcctc
     5101 ggcgggctgc tcggctcccg gctggcgccc cgagtggtgg cccggtacgg ccgacgcgcc
     5161 gtcttccgca ccgtcggcac cctgcgcgcc gtctggctgc ccggcctggc cctcgtccgg
     5221 cccggcgttc ccggcctggt caccgtgatg gccgtcgagc tggcgatcat cgtccacatg
     5281 agcctgtaca ccccggtgct cgccacctac cggctcgaac acacccccgc ccacctggtc
     5341 acccgcaccc tgaccgcctg gtcggtcggc cagcaggccg ccatcgccac cctcaccgcc
     5401 ctcggcggcc tgctcgccca cttcaccggc ccgcgcaccg ccctcgcggc cgcgggcgta
     5461 ctgatcctgg ccaccccgct cctgctgccc cgcaacaccc ggcaccagca cgcaccgcac
     5521 cccgagccgg aaccgtcccg cagccgggct tgaggcgccg ggacttgcca cccggcatcc
     5581 ggcactcgcc atccggcact cgccatccgg catccgccgt ccgccgccat tcacctgcca
     5641 cccgtcaccc gtcacccgtc acccgtatgc cggtgcgcgt ccgcgccgac caggcaccca
     5701 caccgttcga ggaggacccc cgcgtgaacc ccgcccctgc ttccgacact gcccccgacc
     5761 ccatccgcac cgcgcttctc gtcctggact accagcccgc gaccctcgcc ttcgtgcccg
     5821 agggggagga ccgcgactcc ctgctcggcc gggtggcggg ggccgtcgcc gacgtccgcg
     5881 cccacggcgg caccatcgcc cacgtgcgcg ccgccttcac cgaggccgac tgggacgcgg
     5941 tcccggacgc caacaagtcc ttcgccccgc tggcccgcca ccgcgccatg caccacgagg
     6001 acccggccac cgccccccac gagcaactgg ccccccggga cggcgacatc accgtccgga
     6061 agacccgctt cggcgccatg tccaccaccg acctcgaccg gcagctgcgc gcccgcggca
     6121 tcaccaccct ggtcgtctcc ggcctcagca ccggcggagc cgtcctgtcc accgtcctcg
     6181 acgcggccga cctcgactac cgcctctacg tcctgtccga cggcgtcgcc gacccggacc
     6241 ccgaagtcca cgacatcctg ctccgcaagg tcctccccac ccgggcccac gtcatcgaca
     6301 ccgccgccct ccacgccctg ctccggatgg cctgatccgc tgctggcagg atcagccccg
     6361 tggaactcac cgagcaccgc cccgtcgccc cgcgcatgct gctcgcgcgg cggatcgagc
     6421 ggtggttcgt gctggaacgc ccggtgttca tcccggccgg ctgccggttc tggacggaac
     6481 gggacgccct ggtggtcgag catccgacgg gggagcggcg caggtacgcg gggttcgtct
     6541 gccgttaggc cgtctcctcc ggggcctgtc ccggctacgg tgctcgtgtc atggcatccg
     6601 tgttgcgaca ccggtgtcac gtcacctgtg tcgcagcatc aatgtcatgg cacccgtgtt
     6661 gcgacatccg tgccgtagca ctcatgtcat ggcatccgtg tcgcggcatt catgtcgggt
     6721 cacctgtgtc acggcattca tgtcgggaca ttcagtgtcg tgaagtcaac tcccgcttgt
     6781 aacttccaag ttgcgcattg acacggatgt ggcggcgcgg acaccatgga cgccgcccac
     6841 cgcctgtcga caccgttccc ggacgatcgc atatgggagc gctcccacag cgcccgagca
     6901 ggtcacgggc catccgatcg gcacccccac ccccacagcc gccccggaag gacgccatgt
     6961 cccgttcccc cgcgcccccg cccatccggt ccgtgcccgt ccggtccgtg cccgcctcgt
     7021 ccgggcccgg gccgtcgagg tccgttcgcc gtaccgtcct cggactggtc gcggcggggg
     7081 cgctcgccgc cggggcgctg ctgccgttgc acgtggcggc ggccgacacc gcggtggccg
     7141 cgcccgcgtt caactacggt gaggcgttgc agaagtcgct gctgttctac gaggcgcagc
     7201 agtccggcca cctgcccgcg accaaccggg tgagctggcg cggcgattcg gcgttggacg
     7261 acggcaagga cgtcggactg gacctcaccg ggggctggta cgacgccggg gaccacgtca
     7321 agttcggcct cccaatggcc gcgtcgacca ccatgctggc ctggggcggg atcgccgaga
     7381 agcagggcta caccgcctcc gggcagatgc cgtacctgaa gaacaacctg cgcttcgtcg
     7441 acgactacct gatcaaggcg caccccgcgc ccaacgtgct ctacgggcag gtcggcagcg
     7501 gttcggcgga ccacgcctgg tgggggccgg cggaggtgct gccgatggcg cgtcccgcgt
     7561 acaagatcga cgcctcctgc ccgggttcgg acctcgcggg ggagacggcc gccgcgctcg
     7621 cctcctcctc gatggtcttc gccgacagcg acccgacgta cgcggcgacc ctgctcaccc
     7681 acgccaagca gctgtacacc ttcgccgaca cctaccgggg caagtacagc gactgcatca
     7741 aggacgccca gggctactac aactcctgga gcggctacaa cgacgagctg gtctggggcg
     7801 ccatctggct ctacaaggcc accggcgaca gcagctacct ggccaaggcg gagagctact
     7861 acgccaacct ctccaccgag ccgcagtcca ccacgaagtc ctacaagtgg acgatcgcct
     7921 gggacgacaa gtcctacggc gcctacgtgc tgctggccca gctcaccggc aagcagcagt
     7981 acgtcgacga cgccaaccgc tggctcgact ggtggaccgt cggcgtcaac ggcagccagg
     8041 tcaagtactc gccgggcggc gaggcggtgc tcgactcctg gggttcgctg cgctacgccg
     8101 ccaacacctc cttcgtggcg ctggtctact ccgacacgct caccggcgac cccacccgca
     8161 aggccaggta ccacgacttc gcggtccggc agatcgacta cgcgctcggc gacaacccgc
     8221 gcaagtccag ctacctgatc ggctacggcg ccaactcccc gaagaacccg caccaccgca
     8281 ccgcccacgg ctcctggacc gaccagctca ccagccccgt caacagccgg cacaccctga
     8341 tcggcgccct ggtcggcggc cccagctcgg ccgacgactc ctacaccgac gaccgctcca
     8401 actacgtcaa caacgaggtc gccaccgact acaacgccgc cttcaccggc gcgctggccc
     8461 ggctctacgg cgagtacggc ggcagcccgc tcgccgtctt cccgccgaag gagaccccgg
     8521 acggccccga gatgtccgtc caggcctcgg tgaacgccgc cggtaccaac ttcaccgaga
     8581 tcaaggcgta cctgatcaac aagtcggcct ggccggcccg tgcgctcaag aacgcctcgc
     8641 tgcgctacta cttcaccctg gagcccgggg tcagcccgag ccatatcacc ctgaccacca
     8701 actacaacca gtgcggcgcc gtcagcgggc ccacgctgta ctccggctcc acctactacg
     8761 tcacggtcga ctgctccaac accgtgatcg ccccggccgg gcagtccgcc taccgcaagg
     8821 aggtgcagtt ccggatcgcc tcctcgggcg cctgggaccc caccaacgac tggtcgtacc
     8881 agggcatctc gctggtcccg ggctcgacgc cggtggacgc gcccgacatc cggctgctgg
     8941 acgggggcgt gccgcagtgg ggcgccgaac cgggtagcgg caccggctcg tcgccgtcgc
     9001 cgtcgccttc cccctcggcc tcgacctccg cgtcgccgtc cccgtccccg tctccgtccg
     9061 cctcctcctc gccgtcgccg tccccctcgc cgtccgcttc gggttcggcc tcgccgcagc
     9121 cggtctcggg gtgcgcggtg acctacaagg tgggcagcag ttggggcacc gggttcaccg
     9181 ccgacgtgac ggtgcgcaac accggtagcg gtaccgtctc cagctggaag ctgggctgga
     9241 cgtaccgggg caacgaggtg atcagcaacg cctggaacgc ccaggtggtc cagagcggtg
     9301 cggccgtgac cgtcaccgac gccggatgga acgggacgct ggccccgggc ggtaccgcgt
     9361 ccttcggctt ccaggccacc ggcacccccg ccgcgctgcc cgccttcacg ctgaacggca
     9421 ccgcctgcac gaacgcctga cccgcccgac gggctctcgc cccgccgctg tcctcggtct
     9481 ccgtcccgcc cccgtccccg ccgtcgtgcg ggggcggggg cgttcgcgtg ggccggtgga
     9541 cgcgcggctg gagggggagg aaggggatgc ggcggagcgg aacgggtggc cggaaacggc
     9601 cgggtaagtc ggggcggcgg gtgcgcggtg gtgccgcggg ccggtggttc gggggcgact
     9661 cggggcggct gactcaaatg tcgctggcgg cccgggtaaa catcacgatc cgcaagatca
     9721 ccgtatcgag gtaaataccc ccggccgcac gggcgcagcg cgcctacgga gcgttagcgt
     9781 tcctcaagat ccggccgagt cgctcacgag tcctgacgat tcgtcatctt ttcgttcccc
     9841 gaggagcgtt cgccctcgct cgcacgccaa cccaccgata cgccaccaca ccaacacgcc
     9901 agcgcaccag tacgtcggtc gaccacgccc gcacgcccgg gccgaccggc ggcgtccgtc
     9961 cgccctgacc agaccgcccc ctcccagtaa ggagtcacgg atgcccgacc cagggctttc
    10021 ctctccgctc caggccccgc ccgcaccggc cgccgctccg tcgtcaccct ccggcccgcc
    10081 ctccgacccc ttcgcgtcgg ccctcaccgc cgcgctcgcc gcagccaccg cggccgccgg
    10141 gagtgctgcc gggagcgccg gaagcaccgg gagtgccgca ccggccgaga gcgccgaggc
    10201 gagttccgcg ccggtcgaga tcgtcgaggc cgcacccgtg gcggtgtccg gttccgggtt
    10261 gcagcggatc ctgcgcggcc ccagcgggct cgggacgaag ggcctgttcc tggtcaccga
    10321 accgccgcag cccgccgccg tcgagcaggc cgttcagggg ctcgtcgagc ggctcgccga
    10381 gccggtcgcc gaggccgccg ccccggtggt ggacgtgccg gtggagggcg tgccggtgcc
    10441 ggggctgtac ttccacccga tcccggagcc ggacccggcc cgggtcgcgg aggtcagccg
    10501 ccggatcaag gagtgggcgg tcgacgaggt cgacctgttc cccgacgagt gggagggcca
    10561 gttcgacggc ttctcggtcg ggcgctacat ggtcgcctgc cacccggacg ccccgaccgt
    10621 cgaccacgtg atgctggcga cccgcctgat ggtggccgag aacgcggtgg acgactgcta
    10681 ctgcgaggac cacggcggct ccccggtcgg cctcggcggc cggctgctgc tcgcgcacac
    10741 cgcgctcgac ccgctgcaca ccacggcgga gtacgccccg ggctgggcgg agtcgctcgg
    10801 cgccgacgcc ccgcgccgcg cctaccgttc cgcgatgcgg tacttcaccg aggcagccag
    10861 cgcgtcccag gccgaccggt tccggcacga catggcgcgg ctgcacctgg gttacctggc
    10921 cgaggcggcc tggtccgaga ccgaccacgt gcccgaggtc tgggagtacc tggcgatgcg
    10981 ccagttcaac aacttccgcc cctgcccgac catcaccgac agcgtcggcg gctacgaact
    11041 cccggccgac ctgcacgcga tgcccgagac tcagcgggtc atcgcgctcg ccggcaacgc
    11101 gaccaccatc gtcaacgacc tgtactccta caccaaggag ctcgccagcc ccggccggca
    11161 cctcaacctg cccgtggtga tctccgagcg cgagggccgc tccgaccggg acggctacct
    11221 gaaggccgtc gaggtccaca acgagctgat gcacgccttc gagaccgagg ccgccgccct
    11281 cgccgcctcc tgcccggcgc cgccgctgct gcgcttcctg cgcggcgtgg ccgcctgggt
    11341 cgacggcaac caccactggc accagaccaa cacctaccgc tacagcctgc ccgacttctg
    11401 gtgacggtcg gcaggccggc agcgaccgcc aagaccccgc accgatcagt gacagccagc
    11461 agtacccagt gagaaacgga cacctgcaga tgaccagcac cgaactcagc acctccgcca
    11521 ccgcgttcgt tccggcgccc gcgaccgcct accagggcga catcgcccgc tactggaaca
    11581 acgaggcccg cccggtcaac ctgcgcctgg gcgacgtcga cgggctctac caccaccact
    11641 acggcatcgg cgccatcgac accggggccc tcggcacccc cgaggacagc gagtacgaga
    11701 agaagctgat cgccgagctg caccggctgg agtccgccca ggccgaggtg ctcctcgacc
    11761 acctcggtcc gatcgcgccc ggcgacaccc tgatggacgc gggctgcggc cgcggcggct
    11821 cgatggtgat ggcgcaccag cgcttcggct gcaaggtcga gggcgtcacc ctgtccagca
    11881 cccaggccga gttcggcaac cgccgcgtcc aggagctcgg catcgccgac cacgtccgct
    11941 cccgggtctg caacatgctc gacaccccgt tcgccaacgg ccagatgtcc ggctcgtgga
    12001 acaacgagtc cagcatgtac gtcgacctgc acgacctgtt cgccgagcac tcccgggtgc
    12061 tcaaggtcgg cggccgctac gtcaccatca ccggctgctg gaacccgcgc tacggccagc
    12121 cctccaagtg ggtctcgcag atcaacgcgc acttcgagtg caacatccac tcccgccgcg
    12181 agtacctgcg cgcgatggcc gacaaccggc tcgtcccgca ggccgtgatc gacctgaccc
    12241 ccgacacgct gccctactgg gagctgcgcg ccacctcctc gctggtcacc ggcatcgagg
    12301 aggccttcat cgagtcctac aaggacggct cgttccagta cgtgctgatc gcggccgacc
    12361 gggtatgacc cgggtctgac cgggtctggc ccgggcctga ctgggtctga ccggggccga
    12421 tcgccgggcc cggtccccgg cgcgtccacc cgaggagggc tcgcagcgct ccccggtggg
    12481 accttcaccg gtcctgcggc cgtcaccagt tgaagggctc cgacacgtac tgccagcagt
    12541 cggcgccggc ggccccgggg tcgacaccgg ccagccggag ttccagttcg ccgaggacgc
    12601 cgtggcgatc gggcccgccg gtgcggtaca ccgcgaggta gtgctgctgg agggcgacca
    12661 tggtcaggaa ggaccccagg ctgctgcccg ccagcggggc acgcgggtgg gcgtggtccg
    12721 gcgaaccggc cggcagcatc cgcagcaccc ggccggtggc gccgtccagc agcagccggg
    12781 cgcccatcca ccggccgagg gacaggaacg gaccgctccc ggcgggctgc tcgttctccg
    12841 ggacggactc ccaggggtgc ggtgcgaagg cgtccgggcc ggtcggctcc aggcacaggc
    12901 cgaccaggtc cggtacggac ggcacgccca cctcggtgag cagccgccgg gtcgggccgt
    12961 ggacgacccc cgccggcagc tcgtccgccc gcagccggtg cacctgcccg gggccgaacg
    13021 cccgggccag cagcccggcc aggtcggcga ccgccgccgg gtcgaacggc cgggggagca
    13081 cccggcccgg gccgccgatc accggcacca gccgctgttc gggccccgcg cggagcagcc
    13141 cggcgtccag ttcgacggcg tacgcgcccc gcgagtcggc cagcaccacc aggccgccga
    13201 ccgcgacggc gtaccccgcc tcggggtggt ggaacacgcc cagcggcttc ccgtcggcgt
    13261 cgtgcacctc gctgcggtgc cacttctgac gcagcaccag ggcggctccc ggggcagtcc
    13321 gcagcccggc gtccgggccg gtgtccggct cggcgtcccc cggtagcgga ccggccagca
    13381 cctcgcccgt cccggcgtcc cggacgaagc ggaccccccg ctcgtcctcc agcagcacgg
    13441 ccggtcggcc gtccacctcg acggccgtga ggttctccag gtcggactcg tgccgggtgg
    13501 ccggcaggcg gtcgtagtcg cccgggggac gccagtcggc ccacaccggg tggaacagca
    13561 gcggctccgg gcaggactcg gcgagcagcc gggcccgctc cgggcgcccc cgggtgaacg
    13621 cgtccagcgc caggtgcgcc acccagtggc cgtgcggcac gcccgccagg ccgtagccgc
    13681 ccaggtggtg cagcgcggcc gcgtccgtcc ccggcgcgac gccgtccggg tagccgcccc
    13741 ggacgccctc cagcagggcg tcctgcggga ttcgggccag cgcccgggcg tcggccagca
    13801 gcgcgtcgaa ccgtccggcc gccgccgcgt gccccggcag cgcccgcgcc gcccactccg
    13861 gcagcgcggc ggtaccggcg gcgcccagca gcgcgtcggt catccgcccg tgcagcgccg
    13921 tcaggtcgcc cgccgcctcc cgcagcgccc ccgcgagggc gggcgaggcg aaacccaccc
    13981 cggtaccgtc cgcgaccagc cagggcaact cctcggccca ggaagccagt tgaccatccg
    14041 cgacgtccgt cactccggca gcccggcaga gcgccgccca gccctcgacc ggcacccggt
    14101 ggtgttcggc gcacgccagc gcgaccagcg ccgcccgggc cccggccggc actgccgcct
    14161 cgaacgcccg cagctccgcc gccgcgcccc cgccgggcag cgtgagcacc gtcctgcggt
    14221 agcgcgtcgg ctccgggtcg gcgaacaccg gcacccggtc ctgctcgacc accagccgca
    14281 gccggccctc ggaggcgccg atcgacagcc accggaccat ccaccgcagc agctcccgct
    14341 ccccgcccga ggccagcgaa ccggccagct gggggttggc gagcagcacg acgcgcggct
    14401 tgcgctcctt gcgcagcgcc cggaccaggc cgccgaagtc caactgcgcg ccccggctgc
    14461 gcaccccggc gccctcgatc agcccccggg ccaccgcgtc gccgctccgc ccggccgtgt
    14521 ccaccagcaa cgcctccggg aaccgctccg ccagcgccgc cagcacggac gtcttgccgc
    14581 tgcccgccgc gccgcacacg tacagcagac cggggccggt ctcccgcagc cagtcggtcg
    14641 cgtcccggac ggcgtcccgg acggcgtttc gcaccgcgtc ctgtgccgcg tcctgcgcgg
    14701 cgttccgtac ggtgtccggc accgaggccc cggcgcgccc gttcccgtcc gggctcccgt
    14761 ccacgccctg ctccggctcc tgtgcccgct cgctcactgc tggtgcccgc ccgccgtgct
    14821 cggtccggcc gccgttcccg gtggtcagac gaagtcctcc cggtcctgga agacctcggt
    14881 ccagaagtcg gagcgggcca ccaccgggtc cagttccagg gcccagtccc gcagttgccg
    14941 accggagtcg gcgagcgcgg cttcgtcggc gccgcggtag tacgtcgcgt agaggcgcag
    15001 cagcgcggcg aaccgctcga ccgaggaggc catgacgccg ccgtagtagt cgccctccca
    15061 gcgctcggtg gagtagcggg agacccggcc gctctcgccg tccacggtga tcagggtgag
    15121 tccgtcgttg tcggtggcga tcaggtaggc gtgctcgccg agcccggcga agtcggggtc
    15181 ctcgggggag tgcaggtcgg ccgtgcggag ttcggacagg cccttctccg ccagcgtctc
    15241 ggagctgaag tcgagcagcg ggtggcgcac ggcggggaag ccgacctcgg tcaggaaccg
    15301 ccgggtgggc tcgtgccgca ggcccgccgg gaggtcggcc gggtcggacg tccacagcgc
    15361 gtcggcgccg tagtaccggg ccagccactc ccggtcgggc tcgcgggcct ccggcgggag
    15421 cccggcgggc gcgagcgcgg tgaccgccgg ggcggacccg tccacgaagg gcccggtcgc
    15481 cgcgccctcg ttcccgtccc cgtccgtgtc ctcgtcccgg tcctcgtctc cgccctcgct
    15541 ctcgtccggg tcgccgcccg tgtgcagctc gaccgcgtag cagccccagc cgccgccgaa
    15601 cacggccagc cggtccaccc ggacggcgtg ctcgacctgt tcgggcgcgg cgggcagccc
    15661 ggccgtctcg tcgtcccagc cgtccggacc gttcagcacc gcctccccca gttcggggag
    15721 gtcctcgggc agcacgggct cgtacgggtc ggggaggtcg tcggcctcga acgggcggaa
    15781 cagctgcggc cccgccagga cggcgccgtc cgccaggtcg accgcgtact cgtagtagcc
    15841 gtcctcgtcg tccggctcca tccggtccaa ccgggccagt acgtactgct cgtggacgga
    15901 caccaccggg gcgtcctcgt gctccaccac ccggagcgcc acgacccgcc cgccgccggt
    15961 cgggcgggcc gcccgcgcgc ccggcggcac ccagcgggac cacacggtgc gccacggcag
    16021 ccggtacccc gcgtcggcga ggaccgccgc gtcgtccgcc cggccgtggc tgaccagcag
    16081 caggtgcagc caggacagcc actcaccgtg ccgctcggcc ggggggcgca cccccaggcg
    16141 gtccaggtgg tggacgtcct cggccagcgt gccggccggc accccgtccg gccagcactc
    16201 cgccatgccg gcgagcagcc gggtgcggtc gacctgggcg aggaagagcg ggtcctcgat
    16261 cagcgcgggc agctcggcgg gcaggaacga gcggtccggc ctgggggtcg gctcgggtcc
    16321 ggtggtcatg ggcgttctcc gtggtgctgg tcgggcgtgg cgtcgggcgt catcggtgtc
    16381 gcgtcatcgg tgcggcatca ccgatgagac atcaccggtg tggtgccatc gatgagacgt
    16441 caccagtgtg gtgtcaccgg tgtggcgtca tcgatgcctg atcaccgatg cttgatcatc
    16501 gatgtcgcgt ccctgatgtc gcgtcaccga tgactggcca tcggtgacgc gacatttgat
    16561 gtcgggtcac cgatggccag tcatcgatat cgggtcattg atgtggtgtc accggtcggg
    16621 cctccacccc cgggtcagtc caggtccatc gccggctggt actggttgcg cggacggttc
    16681 gggctcagct cgccggtgcg ggccagctcg taccagaggt cgccgacccg gttgaggtgg
    16741 tcctgcatgt cctgcttcag acccgtcgcc gcggcctccc gctcggcctc cgtctggtgg
    16801 ccgggcgcca tctcgccctt ccggtacccg acaccgtaac ccacgtccac gcccggcatg
    16861 ttggaggtca ggtacgccga gcagtggccg tgtccctggc cgccgccgca gggctcccgt
    16921 tcggtccaca ggtgggagat ggtgtagtcg ccggtgttct ggcgctcgtt cagccggtcg
    16981 atccagttgc cgaggtgcgg ctcggagtgc gccgagggcc aggagaagcc gttggtcggg
    17041 atcgaggtgt cgatcacgta ccggacgttg ccgttgccgt cgctggtctc gatcacggcg
    17101 aagttcttcc ccgagaagtc gggccggtgg tcgcccttga ccgccttcac ggtctccttg
    17161 cggacggtcc tggcggcctc gttctcggtc gacccgtgct cttccgtgtg ctgctcgatc
    17221 aggtgctcgc gcaccaggta gccggggtct ggctcccgga gcttggtgcc ctcgggcagg
    17281 ttctcgatgt gcgtgttgcc gcggttgctc cgccagaagt cgtgccgctc gtgcaggtcg
    17341 acgccgcgcg acttctcgtc gaggtggcgg gtgtcgttct tgctcgggtc ggcgtggtcg
    17401 tacgggtggg tgacgtgctc cgggctggcg cccaccgcgt agtcccggtg cacggcgatg
    17461 ctgatccggc cgagctcggc caggacggcg ccgcgctggt cgcggtccag gtgctccagc
    17521 ccgggcagct tctggaacag ctccttctgg tcgaagccga gctggaacgg ctcgtccggc
    17581 ttgcgcttgg cgttggcgtt gacccggtcc gcggtctcct ggaggaagtc gccgagcgac
    17641 ctgtcctcgg cccggtccag caggaactgg tgcgcgacgt cgaggtcgca ctgccggacc
    17701 tcggcgttct cccgctggcg cagcgcctgc tgctgcgcgt ccgggagcat gttgcggtgg
    17761 gtgtggtcct tcgactggtc ctggccgtag ggcgtggagc cctccgggcc gtccgggtca
    17821 gaggtgtggt gcggcgggtg gttcccggtg gagccgtccc cggtcgggtc gtcgtcggtc
    17881 ttctgcttct tggtggccgg gccctcgtgc tcggcctcgt tcttctgctt gccggcgggg
    17941 tcggcgggac ggcggtcggt gtcgcggtcg gaggaggtgc cgtcgggccg ggtgctcccg
    18001 tcgggcccgg tggttccgtc ggacgggatc gggcggcggt cccggtcgag cgggaccgcg
    18061 aacacgccgt ggtcgccgtt gtgcagcggc tggtcgccgc gctgaccggt ctggttgtcc
    18121 aggtaggtga tccggccgtt gtggttgacc acgttccagg cgtgcgcccg gccgtgggcg
    18181 tcctgggtga cgatcaccgc ctgcgaaccg tgccccgact gccggagctg gtcctccagc
    18241 cggtggaacg cctggtcccc gttgccgagg tcgcggaagg gcgcgcccaa ccggtcctcc
    18301 gcccgggccc gcccgccgtg ctcgccgtca ccggtgccgt cgtcgctgcg cggggcggcc
    18361 gcggtcgggc gcccgctgta cgtgtccgcg ctggagagcg ccacgtccag gcagttgttg
    18421 tcccgcccgg gcgcccggtg gccgtcgccg ttgaccgcgc ccggccagtc cccgtacggg
    18481 tccgggtgcc gctgcggggt gccgtccggg ttccgcggga cccggctctc caggtcctgc
    18541 tggtgccgcg ggtcgaccgg ggccagaccg ccgggcacgt cgtgcggccg gctctccgag
    18601 agcggacgct cgtgcggcgg cacggaggag tcgtggtcgc ccttggccgg cgcgtccccc
    18661 ttctccgggg tgtcggagtc cgtcggggtg tcgtggtgcg acgcgtcttc gtggtgtgac
    18721 gggttctcgt gctgcgacgg gttctcgttg cgcgccggat cgtcgtggcg tgccggatcg
    18781 tcgtggcgcg acggcgtgtc gttcttgccg tgctcgggcc cggcgtcggg cgtctgacgg
    18841 tccgcgtgcg gcacgggggc cggtccggcg gcgggccggt ccgtgccggg ccggtccgtg
    18901 ccgggacggt cggcggtggg acgggtggtg gcgtcgggcg tccgggtggg gcggtcgccg
    18961 gacggctgct ggccgagccg gaccggggcg tccggacggt tgttgccggt cgactggggc
    19021 ggcacgccgt tcgggcggtt gcccgacggc ccgtcagccg ggcggccggc gttcggcgtc
    19081 gtgcccccgg tgtgggggcc ggtgccggtg ctgccggtgc ccggggtgtg ggccccgccg
    19141 gtcgggacgc caccgaaacc gggggtggag accgggccgg tcgaggcggg gccggcggtc
    19201 ggggtggccg ggccgctgtc gggcccggac ggccgggacg tcgtgctcgg cggcgcgtcg
    19261 gcgacggcca ccgaggcggt ctcgacggac gccggacggg ccggcccccg gtcgtcctgg
    19321 tcgtggtgcg acgcggcggc cggagcgggc ccgtgcggag gcgtaccggc ggacgcgtga
    19381 cgcggctccg ccccgccacc gccgtgcggc accccgccac cgtgcggcac cgcaccgccg
    19441 ccgcccaccg gaccccgctg gtccggcgca ctctcggcgc ccgactcgtg ccgctgcgga
    19501 ggcaccggcc caccctgcga agagtcgtcg ccccggtgcg gagcctgccc gtcgccgtgg
    19561 tgcgacggcg tggacccgga accgtccccg tgccggtcgg gaccgtggcc cgaaccggag
    19621 tcgtgacccg aaccggggcc gtgcgtcggg gcgggcgcgg agtcgggagc cgtccgcgga
    19681 ccctcgtgcg gcgctcggtg gtcggcggcg ccatcgtgcc ggggcccgtc gtgggacggg
    19741 cgggtgtccg cgccgtcgtg ggtcgggggc cggtggtcgg cggcgtcgtg ggtcgggcgg
    19801 gtggtgccgt tgtcggtggc cgtgctgtgg tcggtgcggg tctcggcgcc gtcgtggcgc
    19861 ggcccgtcgt ggggcggccg ggcgttgttg ttgtcgccgg tggggtggtt gctgccgtcg
    19921 gtacgggtgt cggcgccgtc gtgggtcggg ggccggtggt cggcggtgtc gtgggtcggg
    19981 cgggtggtgc cgttgtcggt ggtcgtgctg tggtcggtgc gggtgtccgc gccgtcgtgc
    20041 gacggacggg gggcgctgtc gccagtcgtg tgctgcgggg tgtcctgcga cggcgggcgg
    20101 tggtcggcac cgttgttggc gctgctgttg ttgcccgtgc tggtgtccgg acggggggcg
    20161 ctgtcggtgg acgtgtgggg cggggtgttc gaactcggct ggccggcacc gctgttgtcg
    20221 cccgtgtggg cggggggctg gtcggtggtg agccgggtgc cgaaggggtc cagcgaggtg
    20281 ttggagcggc cgttgtcgct cgccgcacgg gtcggaccgt tgccgccgct ggtgccggag
    20341 tccgggtgcg agccggacgc ggtgccgtcg gagccgttgc cgccggtgct gccgttcgag
    20401 gcgaggtggc cggacgggcc gccgtccccg gtggacgagg ggtgcgagtt gcccgaagaa
    20461 ccggacgtac cggacgagtt gggggagtgc gtcgacccgg tggattcggt ggacccggtc
    20521 gatcccgtgg agccggtcga ccccgtcccg ctggacccgt tggacctgcc gctcgtgctg
    20581 ctcccgtcgg aactgccact gccgctgcgg ctaccgttcc cggtcccgtt ctcgccgccg
    20641 ttgctgccgc tgccgctgcc gctgtcgtta ccgctgccgg agccggagcc ggagccggac
    20701 ccgctgtcgg agccgttgcc gccgtgcccg gccgcgtggt cgaggccgct gcggacgtgg
    20761 ccgcccgcgc gggagccgac gccgtcgcgg agggactcgg tgaaggtctg gccggcgttc
    20821 ttgaccgagt ccttgaagtc gtcggtgccg cgcttggcgg tgcggcccag gtcgtagccg
    20881 tcctgcgcgc cgaagctctg gttgacggtc tgcgagatca ggtcgctgat catgccctgg
    20941 acggccgaaa cgaccgggtc cttcagcgtt tcgaggatcg cctcgacgag tgcctcgcgc
    21001 agctccttca gcaggcggcg cacgatcatc ttggtggcct gggtggcgcc gagcgcgccg
    21061 acctcggaga ggccgaaggt gaagggggcg gcggcctggg ccgcgatgac ttccgcggcc
    21121 aggatcacca actgcgcgat caccgcgatc ttgcaggcca ccacgatcat cgcggcggcg
    21181 tcgaaggcca tggcgatgag ccgggcggcg ctggccgcgt cggcgaggta gccgtcgccg
    21241 ccggtggaga acttgtcgaa ggccttgccg aaggcgtcga cgtcgtcgcc cgcgttggcg
    21301 gagcggacgc tgttcgcggc ggcgagcgcc tggtagttga cttcgtcgac ctggtccgcg
    21361 aagtcccgcc agacctgcgc gcattcgcgc atccggtcct cgtc
//
