LOCUS       NZ_CP054919            21086 bp    DNA     linear   CON 31-JUL-2024
DEFINITION  Kitasatospora sp. NA04385 chromosome, complete genome.
ACCESSION   NZ_CP054919
VERSION     NZ_CP054919.1
KEYWORDS    RefSeq.
SOURCE      Kitasatospora sp. NA04385
  ORGANISM  Kitasatospora sp. NA04385
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Kitasatospora.
REFERENCE   1  (bases 1 to 8400742)
  AUTHORS   Zhang,B., Shi,J. and Ge,H.
  TITLE     Genome mining for natural products
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8400742)
  AUTHORS   Zhang,B., Shi,J. and Ge,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUN-2020) Institute of Functional Biomolecules, State
            Key Laboratory of Pharmaceutical Biotechnology, Nanjing University,
            No.163 Xianlin Avenue, Nanjing, Jiangsu 210046, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. v2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013364235.1-RS_2024_07_31
            Annotation Date                   :: 07/31/2024 08:11:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,532
            CDSs (total)                      :: 7,423
            Genes (coding)                    :: 7,206
            CDSs (with protein)               :: 7,206
            Genes (RNA)                       :: 109
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 218
            CDSs (without protein)            :: 217
            Pseudo Genes (ambiguous residues) :: 0 of 218
            Pseudo Genes (frameshifted)       :: 81 of 218
            Pseudo Genes (incomplete)         :: 153 of 218
            Pseudo Genes (internal stop)      :: 9 of 218
            Pseudo Genes (multiple problems)  :: 25 of 218
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:10:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3782733
            Orig. end                         :: 3803819
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054919.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="14"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11086](+)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11086
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     gene            436..1974
                     /locus_tag="HUT16_RS16850"
                     /old_locus_tag="HUT16_16845"
     CDS             436..1974
                     /GO_process="GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014136882.1"
                     /locus_tag="HUT16_RS16850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_16845"
                     /product="LCP family protein"
                     /protein_id="WP_176188983.1"
                     /transl_table=11
                     /translation="MSARRAKGGRGGARNRGHRARRIALWATAGTVSLAVLAGGLVYYR
                     LNGNLSTFDEDGVSKDRPAAGSADAQGRTPVNLLLIGSDSRDGANKDLGGGEDGGARSD
                     TAILLHVYADHKHAVGVSIPRDSLVEIPPCMLPNKTWTKDQPSAMFNSAFSVGDTEQGN
                     PACTQNTVEKLTGLRVDHTMVVNFQGFADMTKAVGGVDVCLPKAVYEGDLDPNLGHKGK
                     ELFKQGHQTISGQAALDYVRIRHGLGDGSDIGRTKRQQAFLSSLIKQVKSQGMDPTTLL
                     PLADAATKALTVDQGLGSAAKLIDFAMSLKDVDLHDIKFLTVPWRYQGERVALVHPDAD
                     QLWAALRSDRTLDGQDGSAPPAAGTDSASAEPGPAASGAASAGTPRTDGTGVRVAVYNG
                     TDTPGLTTRAAEALEGSGFTVTGRANAASRTHRSTLVEYGPGERAQAEKVAALFPGAVL
                     EAGGRAGIALTLGADYAADGGTTAAPPVPTGPLPTSVSQARSADDDACADLTYG"
     gene            2078..2587
                     /locus_tag="HUT16_RS16855"
                     /old_locus_tag="HUT16_16850"
     CDS             2078..2587
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUT16_RS16855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUT16_16850"
                     /product="hypothetical protein"
                     /protein_id="WP_176188984.1"
                     /transl_table=11
                     /translation="MDRHTGDGPARQDRDDFGPAPADGTAPADGTAPAARLRDAEPGPP
                     ARSTVPGERLTGWLGALALVVPVVSGSAAAAFFLLGAVLGLSRPHTGLTAPLRTAAWTT
                     VAVAVACALAGLLGLLLTAVWRRGDPPSGPDRTAVPEQRPDGRSGTECPSGTPGRRGVR
                     AARKGQ"
     misc_feature    2662..2677
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.76"
                     /tool="antismash"
     gene            2760..3416
                     /locus_tag="HUT16_RS16860"
     CDS             2760..3416
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUT16_RS16860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_176188985.1"
                     /transl_table=11
                     /translation="MSTPQPGPYPPPGQYPPPGPYPPAGGHPPPQGPYPAQGPYPAQGA
                     YPQQGAYPPGQYAPPPPGAYPPPGQYPPPPAPGGPVVYAPPGGYGARTVPRWRPRQVLT
                     VVGVGLGAIAMGAYWLFGPQDDAGIAQPGQCLYKSGGTATKPILAIVPCTDAKAAYKVL
                     AVKQSSDHSACDDVAGYTTQYAQWSRKKSFSLCLAPNLQHAPRTPAGGASGPATD"
     misc_feature    complement(3517..3530)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.42"
                     /tool="antismash"
     gene            3555..5267
                     /locus_tag="HUT16_RS16865"
                     /old_locus_tag="HUT16_16860"
     CDS             3555..5267
                     /EC_number="6.1.1.15"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /GO_function="GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /GO_process="GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014136885.1"
                     /locus_tag="HUT16_RS16865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_16860"
                     /product="proline--tRNA ligase"
                     /protein_id="WP_176188986.1"
                     /transl_table=11
                     /translation="MRWSQLYVPTLREDPADADAASHRLLVRAGYVRQLAAGHYSLLPL
                     AARVRARIVAVVREEMERIGAQEFLLPALHPAELWRRTGRWESMGEEMFRLTDRKGAEQ
                     ALGMTHEEVFAHLAGELRSYRQLPQVWYQFQTKFRDEARPRSGLLRVREFTMKDSYSFD
                     LDEAGLERSFEAHRRAYLRIFERLGLPAFGVRASSGSMGGSASVEFMSPSAAGEDLVVR
                     CPGCGYAANTEKALSALPAVVDPTDADRPGADRPEEFATPAARTIEELAERHGVAPERQ
                     LKTLVQVVDGVLTLVLLRGDHALVEQKLLDALGASATRAATAEEITAALGASPGSLGPL
                     GGHGLPVVADEALRGRTGLTCGANRDGFHLRGVSVGRDAGVGRWADLREVAAGEACTEC
                     GSALEVLRTIEVGHIFQLGRRYTEALDVAVSGPGGERVVPLMGSYGIGVERVLAALVEA
                     HHDERGIRWPAAVAPFDVVLTVLPDRDGTVAAAAERLYAELGAAGVRVLLDDRAERPGV
                     KFADAELIGVPRRLTVGARSLAAGVVELTARADGAVREVALDAVVAELAGSVG"
     misc_feature    complement(5650..5664)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     misc_feature    complement(5771..5784)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.21"
                     /tool="antismash"
     gene            5775..7034
                     /locus_tag="HUT16_RS16870"
                     /old_locus_tag="HUT16_16865"
     CDS             5775..7034
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971679.1"
                     /locus_tag="HUT16_RS16870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_16865"
                     /product="ATP-binding protein"
                     /protein_id="WP_176188987.1"
                     /transl_table=11
                     /translation="MTKYTANPLLWVLFLVLAAAVLVVVRQRKAAAALRQEIGGLREHY
                     TDLEHHYTQSVASAQEQADEATKTVLKSAMRTLQGLAAEQQLILSRLQDKYGESVILQD
                     LLEVDHTNSQFGRRAQSIAVLCGGWLGRHRDVASVYDVVRSAQGRIRHYRRVEILSQVD
                     FGVSSRAVEPVALALAELLDNATSYSSPDTVVEINIRTVPKGVVIVVDDAGVGMNDEER
                     ARAERLLTTERVNGVGGLGNPPQFGLAVIGVLSERFGFEVSVDSASPYGGVRSVLLLPH
                     ELLTGMPDRRSQPPAASAPMAAQAPAQAPAPVARPAAQPAALPAAAVPPPATESFGSTE
                     DGLPIRRRKRPMAIVPATETAPYGAPAAPAAAASRSGEQTAAILGAFQRGTRSGRATQR
                     DDANQTTSTRGASSEGHEFS"
     gene            7031..7432
                     /locus_tag="HUT16_RS16875"
                     /old_locus_tag="HUT16_16870"
     CDS             7031..7432
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014136887.1"
                     /locus_tag="HUT16_RS16875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_16870"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_030457517.1"
                     /transl_table=11
                     /translation="MNDDLSWMLDSALEIPGALHAVLISADGLLMARTRDIDKDNADRV
                     AAAMSGVQSLSRSLGFFCDNPTQRWQQTLVEFDGGWVFLISAGDGAYLGVSALPDVDMQ
                     DITFRMQQLVGQLGKFLAAPPREDLGVRR"
     gene            7429..7809
                     /locus_tag="HUT16_RS16880"
                     /old_locus_tag="HUT16_16875"
     CDS             7429..7809
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014136888.1"
                     /locus_tag="HUT16_RS16880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_16875"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_176188988.1"
                     /transl_table=11
                     /translation="MKAGGEDFEFEPVDLVRAYVITKGRELPDDQELSLITLVTAAPAE
                     GRRPVRLTPEEARLLDICSAGYLSVAEVAGHTRLPLGVVRIVLASLTEGGHLMTRPPVP
                     RARNADKDLLEEVLNGLHRKFG"
     misc_feature    7471..7473
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7784..8395
                     /locus_tag="HUT16_RS16885"
                     /old_locus_tag="HUT16_16880"
     CDS             7784..8395
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014136889.1"
                     /locus_tag="HUT16_RS16885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_16880"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_176188989.1"
                     /transl_table=11
                     /translation="MGFTASSDDRVGLTTDDYVAGGATQTAVKILVVGHFAVGKTTFIG
                     SISEIEPLSTEETMTRVSESVDDLKGVRGKTTTTVALDFGRLTLSERVVLYLFGTPGQT
                     RFVQMWEDMARGALGALILVDPERLADSFPVIDLIEQYGLDYAIAVNHFDGNPERAERA
                     LREALDLLDETPVVTCDARNEKSSAAALTTLVRYLLDRAS"
     gene            8411..9733
                     /locus_tag="HUT16_RS16890"
                     /old_locus_tag="HUT16_16885"
     CDS             8411..9733
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972616.1"
                     /locus_tag="HUT16_RS16890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_16885"
                     /product="cytochrome P450"
                     /protein_id="WP_176188990.1"
                     /transl_table=11
                     /translation="MDTHSPAPVPPPGCPAHGGRVPLYGPEFAANPQSYYDYLRHYGPT
                     APVELAPGVDATLVTEYSAALQLLQDPTSYRRDSRRWRAFNEGAVPMDSPVLQLLLHRP
                     NVLFADGVEHLRLRQAITDSMARIDQRKLARSTRQISDFLIAQFGYRGSSDLLSSYAKQ
                     LPLFVFNELFGCPADIGDRVMFGISGMFDGVNAEKSAQVLYGAVGELVALKRSRPGEDV
                     TSWMMQHHAKLTDEEMTHQLALLLGAGVEPLGNLLGNTLHRLLVHDAYAHQGGLIDEAI
                     DDTLWENPPITNMGPHYPVADGEFAGEKVEAGDLMLVSFAAANSSPILAAERRASSRAH
                     LAWGAGPHACPSKDPARQIAMTALENLFNQLPDIELAVPEETLSWRPGPFNRALVSLPV
                     RFTPNASDQRPQAAETAQTAKAAQPAAKGGRWSQFLNWLSR"
     misc_feature    9796..9811
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.58"
                     /tool="antismash"
     gene            10001..11086
                     /locus_tag="HUT16_RS16895"
                     /old_locus_tag="HUT16_16890"
     CDS             10001..11086
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0009820 - alkaloid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971675.1"
                     /locus_tag="HUT16_RS16895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_16890"
                     /product="tryptophan dimethylallyltransferase family
                     protein"
                     /protein_id="WP_254897838.1"
                     /sec_met_domain="indole_PTase (E-value: 9.6e-122, bitscore:
                     405.1, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSHTGRQLLSLCELVGLDAGDCAGYARALTDALGPVVRRSLDLP
                     PAAPTFLSDDHTPVEFSLSFSPGAAAPSLRVLFEPSSGFGTLAESSRLGLRALHGLAQR
                     WGISTEQLDLVQDLFLPDDPRGSFALWITLELTAGGTPRMKAYLNPAAAGPDRAGATVR
                     EALDRLGHHRAYDSLPPADRLLLFALDLGDWAAPRLKVYTAHHRLRASAVGALDRMAGG
                     PSPAETEAFLYTAAGLPAGHDGVFDRRPVLACHSFTDPAADRPSGFTLHVPVRDYAHHD
                     REVLDRAEKLLPRYGIAPDVLRDALGALTPRRLEDGVGLIAYLAMVHQQGHDPRLTAYL
                     SSEAYRVRPPNERPTGPRPVL"
     gene            complement(11249..12538)
                     /locus_tag="HUT16_RS16900"
                     /old_locus_tag="HUT16_16895"
     CDS             complement(11249..12538)
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FMO-like"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125675.1"
                     /locus_tag="HUT16_RS16900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_16895"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_176188991.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.4e-11, bitscore:
                     42.2, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FMO-like (E-value: 2.6e-77, bitscore:
                     259.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVCVIGAGLSGLAAAYALREAGLDFVCLEAAAEVGGVWRDRAPG
                     ERGPAYRALHLNTAKALTAFKAFPMDEDLPMYPSRRDMAEYLRAFAERAGLLPYVEFRT
                     EAVSVRQDGHGAWRVVSRDVHGMESVRVFDQVVVASGHHTVPLVPDPLPPGAESFTGRI
                     LHSMEYADGADFAGLRVVVVGLGASGVDIAVDLSRHAARTMVSVRRGQHVVPKQLFGIS
                     VEEIAVAPWFTAKSLPEQQEFIEEALRVARGPLSGYGLPEPENRIFATPVTISDEVLSR
                     IRHGAVLPKPGIESLAGSTVRFTDGSTAEVDAIVYCTGYGWSFPFLPADHPAGGHGPVP
                     LYRRMVDAERPGLFFLGLFRPVGSITRLVEAQAQWLVRLVTGASVLPAAEVMRKETDGH
                     LAGIERRYGLSAGSSLQVDVNGYLRELTGA"
     gene            12831..16349
                     /locus_tag="HUT16_RS38235"
     CDS             12831..16349
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514257.1"
                     /locus_tag="HUT16_RS38235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_254897839.1"
                     /transl_table=11
                     /translation="MTEHGPADPADPSGFGALLRELRTRAGINQQTTATRAGLSARALR
                     DLEHGRVRRPRARTVHRLADALALTTDQAAALRTAATRDDHAPGTGRTTLLLLGPLLLR
                     RGRDTVPIGSPTLHRLLGLLALTHPAAATRQEITDTLWPAGPPASQQSLVHTHVSRLRR
                     LLSPDDPDDPAAGVVRTPTGYRLGLPRHRTDLGRFDDLLARTTCLWHAPDPDAAHQDLT
                     RALRHWRGPVLADADPALRRHPAAVAANERRIRAALLHADTALLLRRPDHSVPLLRELA
                     HTEPLHEGLHARLILTLAASGRQADALDTYTRLRTRLDEELGVTPGPELHDAHLRVLRG
                     LPGPTATRPAPRATGEHWPLPHTPDAPDAPNALDAQPRVLPGPTAGWPPPRAAGEHQSL
                     PHTPNAPNAPGIPNTLGAFPKPAQLPPTTGPFVGRHRQLSALDALLPADPDHLDHPGEP
                     AARPPLLVVVGPPGIGKSALAAHWAHRHRDRFPDGQLFADLRGHSARPAPHPDEVLARF
                     LRALGTPPDRLPADPDEAAALYRTLLADRRLLVLLDDARDAEQVRPLLPGAPGCAVLVT
                     GRTRLTGLVAGDGARRLTLDPLDPAEGALLLGSVLGPCRVAAEPAAAHRLVRACGGLPL
                     ALRLAAADLTTRTTALADYAPAHPDAAHPDAALLARLDLADDPRTGLRAAFGHSYRVLP
                     APARRMFRLLGRAPAAGLTAATATALAATGPTETTALLDRLADAHLVREEPPGHYRLPG
                     LLHPYAAGLAAEGDEGCGGGCGDGGSGAVDVNPLIDAHQQFGGDQWIDVEQPPTISGLT
                     GRQHPNATATRVCDAEPAEAKHELTHRPLIPVAPVPPRDLASGGSDGRGGPHPDDITVL
                     GLICWKLGRLPEAAEHFTQAARVLATGPATNSGPGPAPATSSGPATATATGSGHSGGAS
                     DREAIARTNLAVVQRALGRPGEAIRGIGEALPVHRWHRNRFSEAVALSCLSRAHTDLGD
                     HATGRLLAHSALAAARAGRSRALEAGARLALADSYLRAHRPAEATAAYREALRSAEASG
                     DRHPQAAALAGLAAALIETDPRAALRTAERALALARAAEYRVLEGDALTVLARVHVRLC
                     EPHAALALGADALALHRATGHRPGETRTRLVLALAAAALGADADAVRHRREALLLVRAT
                     GGTPPR"
     gene            16505..17188
                     /locus_tag="HUT16_RS16910"
                     /old_locus_tag="HUT16_16910"
     CDS             16505..17188
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014136894.1"
                     /locus_tag="HUT16_RS16910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_16910"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_176188992.1"
                     /transl_table=11
                     /translation="MSRYDRLARTPSVRRVQQEMGSAAAAERRLRTSDDAPDDRPDDGP
                     EPLSAAAAAFVQGLDGFLFATVNEDGWPYIQHRGGPPGFVHVLDPYTLGYLDVRGNRQY
                     LTTGNLRGGDGRVALFFLDHARQARLKVFGRATAVPADRDPDLARRLATPRTDGRVEQL
                     VTISVEAHAWNCPNHITPRFTERELADVLDPIRDRLARLERENALLRAELAAATGAHPS
                     SRPKD"
     gene            17196..18482
                     /locus_tag="HUT16_RS16915"
                     /old_locus_tag="HUT16_16915"
     CDS             17196..18482
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967145.1"
                     /locus_tag="HUT16_RS16915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_16915"
                     /product="MFS transporter"
                     /protein_id="WP_176188993.1"
                     /transl_table=11
                     /translation="MPTGLTDHPAAAAATAPGPAIWSRNFRRYFTARSAGLLSWAMLPV
                     AVSAGLLSAGHGLDTAGYAMAFLVAPFAGLVLFGGVLADRFTARRMMIVADLTNLTAHV
                     LLAALFWHGVDRLWQLYALLAVAGTANALFQPGAASTVPLIARDVQGANGVLRTSEAIT
                     GLGGPALAGVLVGFGSTGWVMALSALAYATSAACLFALRLGAVPAPPAGHSFRHDLAVG
                     WHEFRSRSWLWGVILIWMVYAVLAWGPQLSLAAGVVVPAHGPTAFGLVNCALGAGTVAG
                     GLLAIRYKPRRPLAAGAVAMFAYPLYPLAILLHAPVWLLAAAQVLVGTGIGVWGVMWST
                     AVQTQVPGEVLNRVHAYEVAGSVGLYPIGSALAGPAAHAFGTSHVLAAGTLVALLTPAA
                     LLLARPVRTLPRIPDRPAAHPNDPSPHPG"
     misc_feature    18862..18876
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     misc_feature    18945..18958
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.35"
                     /tool="antismash"
     misc_feature    complement(18948..18961)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.06"
                     /tool="antismash"
     misc_feature    complement(19160..19174)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.92"
                     /tool="antismash"
     gene            19194..20078
                     /locus_tag="HUT16_RS16920"
                     /old_locus_tag="HUT16_16920"
     CDS             19194..20078
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUT16_RS16920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUT16_16920"
                     /product="hypothetical protein"
                     /protein_id="WP_176188994.1"
                     /transl_table=11
                     /translation="MSNVDWQTVLANIGDIPPERRLYRDTEDIYFGEPVVAGGRMHLGV
                     ARLRDRDIQQIDWVHGRIDHLQLEENRSIVDTTVVSFLPYGNIIGVLQGTMSAPRPSAV
                     QRWLNSMDSGLDRDIAVVPLIGRNAREKLKRAEAINFFEVRLRPGPDLLDSDVAGLGDL
                     SRRAHRHNPNALITLTMKIPKQGPFSRGTRRSRGESQLREDVLGFISQYASLVGEGGAV
                     DRAIAHVVLPNGDGDLIEEKINFVSDHITAQRQVMMRRSEGGAPWHEAAVRAITQVATE
                     CERELRDAVSAVP"
     gene            20165..20644
                     /locus_tag="HUT16_RS16925"
                     /old_locus_tag="HUT16_16925"
     CDS             20165..20644
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUT16_RS16925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUT16_16925"
                     /product="hypothetical protein"
                     /protein_id="WP_176188995.1"
                     /transl_table=11
                     /translation="MDWVLAVAITISHGFISGKHLLAENSADQRMSIYATVASVAAIIG
                     GFGTAAISQYASSSGRRMTFIRVRFGPSLRRNWVSILVSMSEVSIGCLAVMIYDSGENL
                     GRAGWLLEAVLVLGILRTIRLIWLFRLLIDVSDHDGASGGGPEEVRVVRRNNPGI"
ORIGIN
        1 cgcgccgagt cggccgaggc ccgcaggcac cgccgcgacg ccgacctgga cctcgcccag
       61 gtcaccgtgg tgcacctggg actgctccgc acccactgat cccccgcccg gccgcagccg
      121 acgggggatc cgccgttccg gggcgcccgc cccgcccgca tccgcccgcc gcacccctat
      181 ccgcccgccg caccgacttc cggcccgccg acttccggcc cgccgacttc cggcccgccg
      241 acttcagccc gtcgacttcc ggcccgcccg ccgacgcgtc gaccgccgca cccgggcccc
      301 gtcccctccg cccgcacccg cccgatcggg cccggtgcgg cacgggtgtg acttcacccg
      361 accgggtttg tatgcttcgc tcgacttcta cagccatgta gaagttcggc cgacggcaac
      421 gggtgagggg gcgtcatgtc cgcacgcagg gcgaagggcg gtcgcggcgg cgcacggaac
      481 cgcggccacc gggcgcggcg gatagccctg tgggccaccg cgggcaccgt ctcgctggcc
      541 gtcctggccg gcggcctggt ctactaccgg ctgaacggca acctgagcac cttcgacgag
      601 gacggcgtca gcaaggaccg gcccgccgcc gggagcgccg acgcccaggg ccgcaccccc
      661 gtcaacctgc tgctgatcgg gtccgactcg cgcgacggcg ccaacaagga cctcggcggc
      721 ggcgaggacg gcggcgcccg ctcggacacc gcgatcctgc tgcacgtcta cgccgaccac
      781 aagcacgccg tcggggtgtc catcccgcgc gactcgctgg tcgagatccc gccctgcatg
      841 ctgccgaaca agacttggac caaggaccag cccagcgcca tgttcaacag cgccttctcg
      901 gtcggcgaca ccgagcaggg caacccggcc tgcacccaga acaccgtgga gaagctcacc
      961 gggctgcggg tcgaccacac catggtggtc aacttccagg gcttcgccga catgaccaag
     1021 gcggtcggcg gcgtcgacgt ctgcctgccc aaggccgtct acgagggcga cctcgacccc
     1081 aacctcggcc acaagggcaa ggagttgttc aagcagggcc accagaccat ctccggccag
     1141 gccgcgctcg actacgtccg catccggcac ggtctcggcg acggctccga catcggccgc
     1201 accaagcgcc agcaggcctt cctgtcctcg ctgatcaagc aggtcaagtc gcagggcatg
     1261 gaccccacca cgctgctgcc gctggccgac gccgccacca aggcgctcac cgtggaccag
     1321 ggcctgggct cggccgcgaa gctgatcgac ttcgccatgt cgctcaagga cgtcgacctg
     1381 cacgacatca agttcctcac cgtgccctgg cgctaccagg gcgaacgcgt cgccctggtg
     1441 caccccgacg ccgaccagct gtgggccgcg ctccgcagcg accgcaccct ggacgggcag
     1501 gacggctccg cgccgcccgc cgccggcacc gactccgcct ccgccgagcc gggccccgcc
     1561 gcgtccggcg ccgcctccgc cgggacgccg aggaccgacg gcaccggtgt cagggtcgcc
     1621 gtctacaacg gcaccgacac ccccgggctg accacccggg ccgccgaggc gctggagggc
     1681 tccggcttca ccgtcaccgg ccgggccaac gccgcctccc gcacccaccg cagcaccctg
     1741 gtcgagtacg ggcccggcga gagggcccag gccgagaagg tcgccgcgct gttccccggc
     1801 gccgtcctgg aggccggcgg ccgggccggg atcgcgctca ccctgggcgc cgactacgcc
     1861 gccgacggcg gcaccaccgc cgccccgccg gtgcccaccg gcccgctgcc caccagcgtc
     1921 agccaggccc gctccgccga cgacgacgcc tgcgccgacc tgacctacgg ctgagactcg
     1981 cgaccgagac ccgcggccgg ggcccacggg cctccggccg aaccgcaccc gtacgcgccc
     2041 gcacgagcac accaccactc acggggggac aacggcgatg gaccggcaca ccggcgacgg
     2101 ccccgcccgg caggaccggg acgacttcgg gcccgccccg gccgacggca ccgccccggc
     2161 cgacggcacc gccccggccg cccggctgcg ggacgccgag cccggcccgc ccgcccggag
     2221 caccgtcccg ggcgagcggc tgaccggctg gctgggcgcg ctggccctgg tggtgccggt
     2281 cgtcagcggc agcgccgccg ccgcgttctt cctgctcggc gccgtcctcg gcctgtcccg
     2341 cccgcacacc gggctcaccg cgccgctgcg caccgccgcc tggaccaccg tcgccgtcgc
     2401 ggtggcctgc gcgctggccg ggctgctcgg cctgctgctg accgccgtct ggcggcgcgg
     2461 cgacccgccg tccggaccgg accggacggc ggtgcccgaa cagcggcctg acggccggtc
     2521 gggaacggag tgcccgtcag gaacgcccgg gcgccggggg gttcgggcgg cacgaaaagg
     2581 gcaataacca ccgggggcgt tccgaaatgg ccgggccatt cgtggccaaa tgccggattc
     2641 acgccgattt cccggcaaag aaaaggcaat gattccccgg cgttcgcccc attccttccc
     2701 ggccgcctgg ctacgcttcg tcggcctgtt acgcctttcc cgccgcgaag gaagaatccg
     2761 tgagcacacc ccagccgggc ccgtacccgc cgccgggcca gtaccccccg cccgggccgt
     2821 acccgccggc cgggggccac ccgccgccgc agggcccgta cccggcgcag ggcccgtacc
     2881 cggcgcaggg cgcttacccc cagcagggcg cgtacccgcc gggtcagtac gctccgccgc
     2941 cgccgggtgc ctacccgccg ccgggtcagt accccccgcc gcccgcgccc ggcgggccgg
     3001 tcgtgtacgc gccccccggc ggctacggcg cccgcaccgt gccgcgctgg cggccccggc
     3061 aggtcctgac cgtggtcggg gtcggcctcg gcgcgatcgc gatgggcgcc tactggctgt
     3121 tcggcccgca ggacgacgcg ggcatcgccc agcccggcca gtgcctgtac aagtccggcg
     3181 gcaccgccac caagccgatc ctcgccatcg tgccgtgcac cgacgccaag gccgcgtaca
     3241 aggtgctcgc ggtgaagcag agcagcgacc actcggcctg cgacgacgtg gcgggctaca
     3301 ccacccagta cgcgcagtgg agccggaaga agagcttcag cctctgcctg gccccgaacc
     3361 tccagcacgc cccgcgcact ccggccggcg gggcgagcgg cccggcgacc gactgaggcg
     3421 gcggcggtcc ggcccggccg ggggcggtgc gccgcccccg gcccgcggcg gcgcggaatt
     3481 attcggagcg cccgaatccg ggtaacggtt agaatccgaa ctcattttcc gcgggccgag
     3541 aggacggtgt cccgatgcgc tggtcgcagt tgtacgtacc caccctgcgg gaggacccgg
     3601 ccgacgccga cgccgccagc caccgcctgc tggtccgcgc cgggtacgtg cggcagttgg
     3661 cggcgggcca ctactcgctg ctgccgctgg cggcccgggt ccgggcccgg atcgtcgcgg
     3721 tggtgcgcga ggagatggag cggatcgggg cgcaggagtt cctgctgccc gcgctgcacc
     3781 cggccgagct gtggcggcgc accgggcgct gggagtcgat gggcgaggag atgttccgcc
     3841 tgaccgaccg caagggcgcc gagcaggccc tcgggatgac ccacgaggag gtgttcgcgc
     3901 acctcgccgg ggagttgcgc tcgtaccggc agctgcccca ggtctggtac cagttccaga
     3961 ccaagttccg ggacgaggct cggccccgct cgggcctgct gcgggtgcgc gagttcacca
     4021 tgaaggactc gtacagcttc gacctcgacg aggccggcct ggagcgctcc ttcgaggcgc
     4081 accggcgggc ctacctgcgg atcttcgagc ggctcgggct gcccgcgttc ggggtgcggg
     4141 cctccagcgg cagcatgggc ggcagcgcct cggtggagtt catgagcccc tcggcggcgg
     4201 gcgaggacct ggtggtgcgc tgcccgggct gcgggtacgc ggcgaacacc gagaaggcgc
     4261 tgtccgcgct gcccgccgtc gtcgacccga cggacgccga ccggcccggc gccgaccggc
     4321 ccgaggagtt cgcaacgccc gcggcgcgca ccatcgagga gctggcggag cggcacggcg
     4381 tcgcgcccga gcggcagctg aagacgctgg tgcaggtggt cgacggggtg ctgacgctgg
     4441 tgctgctgcg cggcgaccac gccctggtcg agcagaagct gctggacgca ctgggcgcct
     4501 cggcgacccg ggccgccacc gccgaggaga tcaccgcggc gctcggcgcc tcccccggca
     4561 gcctcggccc gctgggcggc cacggcctgc ccgtggtcgc ggacgaggcg ctgcgcggcc
     4621 gcaccggcct gacctgcggc gccaaccggg acggcttcca cctgcgcggg gtgtcggtcg
     4681 ggcgggacgc cggggtcggc cgctgggcgg acctgcggga ggtcgcggcg ggcgaggcct
     4741 gcacggagtg cgggtcggcc ctggaggtgc tgcgcaccat cgaggtcggg cacatcttcc
     4801 agctcggccg ccgctacacc gaggcgctgg acgtggcggt ctccgggccc ggcggcgagc
     4861 gggtggtgcc gctgatgggc agttacggca tcggcgtgga gcgggtgctg gccgccctgg
     4921 tggaggcgca ccacgacgag cgcggcatcc gctggcccgc cgcggtcgcc ccgttcgacg
     4981 tggtgctgac ggtgctgccc gaccgggacg ggacggtggc ggcggcggcc gagcggctgt
     5041 acgcggagct gggcgcggcg ggcgtgcggg tgctgctgga cgaccgggcg gagcggcccg
     5101 gggtgaagtt cgccgacgcc gaactgatcg gcgtgccccg gcggttgacc gtcggcgcgc
     5161 gttcgctggc ggccggggtg gtggagctga ccgcccgggc ggacggcgcc gtccgcgagg
     5221 tggcgctcga cgcggtggtg gcggagctgg ccgggtcggt cggctgagcg cgcgcgtcgg
     5281 cctccgggcg cccgggggcc gacgcgtacg cggcgcacac agggggcgga ttccgtgcag
     5341 acccggtgtg cgtgctgcgg gggccgggtg ggccggatgt ccccgcctta acggcgggtt
     5401 gcgccccgtg aagttccggg cgccgcgacc ggcatagcac cccgacgagc gactcctcgg
     5461 gatttcgccg gaaaaacccc gatccgacgc gtcgctaccg cactgtccgg cctccctgtg
     5521 gtagaagccc cgatgggagg cggtgcgcgg gccggagcgg cccggccgga ggctcgggcg
     5581 gctcggcaac agggcactga cctggggttc caactacccg cgtccacccg ggatgagacg
     5641 gatcttcaca tcgacgctga cgatcgttca cctattcgcc cgatgatacg atcatcccgc
     5701 ttgggggagc ggcgggttca ccctgcgatg acggggattc agcagtcggc cgccagtcgc
     5761 ctgaagagag tcttatgacg aaatacacag cgaacccatt gctctgggtt ctcttcctcg
     5821 tcctggccgc cgcggtcctt gtcgtggtcc gccagcgcaa ggcagccgcg gcactccgac
     5881 aggagattgg cgggctccgg gagcactaca ccgacctgga gcaccactat acgcagtcgg
     5941 tcgcctccgc tcaggaacaa gcggacgaag caaccaaaac ggtattgaag tccgccatgc
     6001 ggacgctcca gggcctggct gcggaacagc agttgatcct ctcccggctg caggacaagt
     6061 acggcgagtc ggtgatcctg caggacctgc tggaggtcga ccacaccaac tcgcagttcg
     6121 gccgccgcgc ccagtccatc gccgtgctgt gcggcggctg gctcggccgc caccgcgacg
     6181 tcgcctcggt gtacgacgtg gtgcgctcgg cccagggccg catccgccac taccgccggg
     6241 tggagatcct ctcccaggtg gacttcggcg tctccagccg cgcggtggag ccggtcgccc
     6301 tggcgctggc cgagctgctc gacaacgcga cctcgtactc cagccccgac accgtcgtcg
     6361 agatcaacat ccgcaccgtg cccaagggcg tggtgatcgt ggtggacgac gccggcgtcg
     6421 gcatgaacga cgaggaacgg gcccgcgccg aacggctcct gacgaccgaa cgggtcaacg
     6481 gcgtcggcgg cctcggcaac ccgccgcagt tcggcctcgc cgtgatcggc gtgctctccg
     6541 agcgcttcgg cttcgaggtc tcggtggact ccgcctcccc gtacggcggc gtccgctccg
     6601 tcctgctgct accgcacgaa ctgctgaccg gcatgccgga ccggcgctcc cagccgcctg
     6661 ccgcgtccgc cccgatggcc gcccaggccc cggcccaggc gcccgccccc gtggcgcgac
     6721 cggcagcgca gccggccgcg ctccccgccg ccgcggtccc tcccccggca accgagtcgt
     6781 tcggctccac cgaggacggc ctgccgatcc gccgccgcaa gcggccgatg gcgatcgtcc
     6841 cggccaccga aaccgccccc tacggcgcgc ccgcagcgcc cgccgccgcc gcgtcccgct
     6901 ccggggagca gaccgcggcg atcctggggg ccttccagcg cggcaccagg tccggtcgcg
     6961 ccacccagcg ggacgacgcg aaccagacga ccagcacccg cggtgcaagc agtgaagggc
     7021 atgagttctc gtgaacgacg atctgtcttg gatgctcgac agcgcgctgg agatcccggg
     7081 ggccctgcac gcggtcctga tctccgccga cggcctgctg atggcccgta ccagggacat
     7141 cgacaaggac aacgcggacc gggtggccgc cgcgatgagc ggcgtgcagt cgctctcccg
     7201 ctcgctcggc ttcttctgcg acaacccgac ccagcgctgg cagcagaccc tggtcgagtt
     7261 cgacggcggc tgggtgttcc tgatctccgc cggtgacggc gcctacctgg gggtgtccgc
     7321 gctgccggac gtcgacatgc aggacatcac cttccggatg cagcagctcg tgggccagct
     7381 cggcaagttc ctcgccgcgc cgccccgcga ggacctcggg gtccgccggt gaaggcgggc
     7441 ggcgaggact tcgagttcga gccggtggac ttagtccgcg cctacgtcat caccaagggc
     7501 cgggagctgc ccgacgacca ggagctctcc ctgatcaccc tggtcaccgc cgcccccgcc
     7561 gagggccgcc gccccgtccg gctcacgccg gaggaggcgc ggctgctcga catctgttcg
     7621 gccggctacc tgtcggtcgc cgaggtggcg ggccacaccc ggctcccgct gggcgtggtc
     7681 cgcatcgtgc tggcctcgct caccgagggc ggccacctga tgacccgtcc gccggtcccg
     7741 agggcccgga acgcggacaa ggaccttctg gaggaggtgc tcaatgggct tcaccgcaag
     7801 ttcggatgac cgggtcgggc tgaccaccga cgactacgtc gccggcggcg ccacccagac
     7861 cgccgtgaag atcctcgtcg tcgggcactt cgccgtcggc aagaccacct tcatcggttc
     7921 gatctccgag atcgaaccgc tgtccaccga ggagaccatg acccgggtct ccgagagcgt
     7981 cgacgacctc aagggcgtcc ggggcaagac caccaccacg gtcgcgctgg acttcggccg
     8041 gctcaccctc agcgaacgcg tggtgctgta cctgttcggc acgcccggcc agacccgctt
     8101 cgtccagatg tgggaggaca tggcccgcgg cgccctcggc gcgctgatcc tggtcgaccc
     8161 cgaacggctc gccgactcct tccccgtgat cgacctgatc gagcagtacg ggctggacta
     8221 cgccatcgcc gtcaaccact tcgacggcaa cccggaacgc gccgagcggg cgctgcggga
     8281 ggccctcgac ctgctcgacg aaaccccggt cgtcacctgc gacgcgcgca acgagaagtc
     8341 gtcggccgcc gcactcacca ctctcgtccg ctatttgctg gaccgcgcca gctaggagca
     8401 acacgcagcc atggacactc actcccccgc cccggtgccc ccgcccgggt gcccggccca
     8461 cggcggccga gtgccgctgt acgggccgga gttcgcggcc aacccgcagt cctactacga
     8521 ctacctgcgg cactacggcc ccaccgctcc ggtcgaactc gcccccgggg tcgacgccac
     8581 cctggtgacc gagtactcgg ccgccctgca gctgctgcag gaccccacct cctaccgccg
     8641 ggactcccgc cgctggcggg ccttcaacga gggcgccgtc ccgatggaca gcccggtgct
     8701 gcaactgctg ctgcaccgcc cgaacgtgct gttcgcggac ggcgtcgagc acctgcggct
     8761 gcgccaggcc atcaccgaca gcatggcccg gatcgaccag cgcaagctcg cccgcagcac
     8821 ccggcagatc tccgacttcc tgatcgccca gttcggctac cgcggttcga gcgacctgct
     8881 gagctcctac gccaagcagc tgccgctgtt cgtcttcaac gagctcttcg gctgcccggc
     8941 cgacatcggc gaccgggtga tgttcggcat ctccggcatg ttcgacggcg tgaacgccga
     9001 gaagtccgcc caggtgctgt acggcgcggt cggcgagctg gtcgcgctca agcgcagccg
     9061 ccccggcgag gacgtcacct cctggatgat gcagcaccac gccaagctca ccgacgagga
     9121 gatgacgcac cagctggccc tgctgctggg cgcgggcgtc gagccgctcg gcaacctgct
     9181 cggcaacacc ctgcaccggc tgctcgtgca cgacgcctac gcgcaccagg gcggcctgat
     9241 cgacgaggcg atcgacgaca ccctctggga gaacccgccg atcaccaaca tgggcccgca
     9301 ctacccggtt gccgacgggg agttcgccgg cgagaaggtc gaggccggcg acctgatgct
     9361 ggtgagcttc gcggccgcca acagcagccc gatcctggcc gccgagcggc gcgccagcag
     9421 ccgcgcccac ctggcctggg gcgccggacc gcacgcctgc ccgtccaagg acccggcccg
     9481 gcagatcgcc atgaccgcgc tggagaacct gttcaaccag ctgccggaca tcgaactggc
     9541 cgttcccgag gagacgttga gctggcggcc cggcccgttc aaccgcgccc tggtctcgct
     9601 gcccgtccgg ttcaccccga acgcctccga ccagcgcccg caggccgccg agaccgccca
     9661 gacggccaag gccgcgcagc ccgccgcgaa gggtgggcgt tggagccagt tcctcaactg
     9721 gctcagcagg tgattctcgc aacacttatg tggccgtgat tacggcatga atcctgaaaa
     9781 acccgggtaa tcagcgcgaa tgcctgcgcc atatgccatg gcgccgatga ccggagaaca
     9841 ggagggtgtc atggaccaca tatccagaga cgccgccgag acccgcagcc cgctcctccc
     9901 ggggccagcc gcccccggcg gtcgtcccct tcgcaccgat gtcccccggc cgcacggccg
     9961 ggggacatct ctgttgccac ccgcaccctc cgggcggacc gtgggcagcc acacgggccg
    10021 tcaactgctc tccctgtgcg agctggtggg cctggacgcg ggcgactgcg ccggctacgc
    10081 ccgcgccctg accgacgcgc tcggaccggt ggtgcgccgc tcgctcgacc tgccgcccgc
    10141 cgccccgacc ttcctctccg acgaccacac cccggtcgag ttctcgctct ccttctcccc
    10201 cggcgccgcc gccccctcgc tgcgcgtcct gttcgaaccc tccagcggct tcggcaccct
    10261 ggccgagagc agccggctcg gcctgcgcgc gctgcacgga ctcgcccagc gctggggcat
    10321 ctccaccgaa cagctcgacc tggtccagga cctcttcctc cccgacgacc cacgggggag
    10381 cttcgcgctc tggatcaccc tggaactgac cgccggcggc accccccgga tgaaggccta
    10441 cctcaacccc gccgcggccg ggcccgaccg ggccggggcc accgtccgcg aggcgctgga
    10501 ccggctcggc caccaccggg cgtacgacag cctgccgccc gccgaccggc tgctgctgtt
    10561 cgccctcgac ctcggcgact gggcggcccc ccggctgaag gtgtacaccg cccaccaccg
    10621 gctgcgggcc tccgccgtcg gcgcgctcga ccggatggcc ggcggcccct cgcccgccga
    10681 gaccgaagcc ttcctgtaca ccgccgccgg gctgcccgcc gggcacgacg gcgtcttcga
    10741 ccgccgcccc gtgctcgcct gccactcctt caccgacccg gcggcggacc gccccagcgg
    10801 cttcaccctg cacgtcccgg tccgcgacta cgcccaccac gaccgcgagg tgctcgaccg
    10861 cgccgagaag ctgctgcccc ggtacgggat cgcccccgac gtgctccgcg acgcgctcgg
    10921 cgccctcacc ccgcgacggc tggaggacgg cgtcggcctg atcgcctacc tggccatggt
    10981 gcaccagcag ggccacgacc cccggctgac cgcgtacctg tcctccgagg cgtaccgggt
    11041 ccgcccgccc aacgaacggc ccaccggacc gcgcccggtg ctctgaccac cgtgctctga
    11101 ccgccgcgct gcacccccgc gcccggcacg ttccaccggg acccaccgcg ccccaccgcg
    11161 gccctcgacg gccgacgacg gccgcagctg tcggagaaga cccgtgaccc cctgtatcac
    11221 gagcctcccc cgaaccctcc gctgcggcct aagcccccgt caactcccgc aggtagccgt
    11281 tcacgtcgac ctggagcgag gacccggccg acaggccgta gcgacgctcg atcccggcca
    11341 ggtgcccgtc cgtctccttg cgcatcacct ccgcggcggg cagcaccgac gcgccggtga
    11401 ccagccgcac caaccactgc gcctgcgcct ccaccagccg ggtgatcgac cccaccgggc
    11461 ggaacaggcc caggaagaac aggcccggcc gctccgcgtc caccatccgc cggtacagcg
    11521 gcaccgggcc gtgcccgccc gccgggtggt cggccggcag gaacgggaac gaccagccgt
    11581 accccgtgca gtagacgatc gcgtccacct ccgccgtgct cccgtccgtg aagcggaccg
    11641 tcgaacccgc cagcgactcg atgcccggct tcggcagcac cgcgccgtgc cggatccggc
    11701 tcaggacctc gtccgagatc gtcaccggcg tcgcgaagat ccggttctcc ggctcgggca
    11761 ggccgtaccc ggacagcggg ccgcgcgcca cccgcagcgc ctcctcgatg aactcctgct
    11821 gctccggcag ggacttggcg gtgaaccacg gggcgaccgc gatctcctcc accgatatgc
    11881 cgaacagctg cttgggcacc acgtgctggc cgcggcgcac cgagaccatc gtccgcgccg
    11941 cgtgccgcga caggtccacc gcgatgtcca cccccgacgc gccgaggccc accacgacca
    12001 cccgcaggcc cgcgaagtcc gcaccgtccg cgtactccat cgagtgcagg atccggccgg
    12061 tgaaggactc cgcccccggc ggcagcgggt ccggcaccag cggcaccgtg tggtggcccg
    12121 acgccaccac cacctggtcg aagacccgca cgctctccat cccgtggacg tcccggctca
    12181 ccacccgcca cgccccgtgc ccgtcctgcc gcaccgacac cgcctcggtg cggaactcca
    12241 cgtacggcag cagccccgcc cgctccgcga acgcccgcag gtactccgcc atgtcccggc
    12301 ggctcgggta catcggcagg tcctcgtcca tcgggaaggc cttgaacgcc gtcagggcct
    12361 tcgccgtgtt caggtgcagc gcccggtagg ccggaccccg ctcccccggc gcccggtccc
    12421 gccacacccc gcccacctcg gcggccgcct ccaggcagac gaagtccagc cccgcctcgc
    12481 gcagcgcgta cgccgccgcg agaccggaca gacccgcacc gatcacacag acactcaccg
    12541 cggcctccat gcagtgttgc actcgaactg accgctctgg cagcgatctt gatgcctcag
    12601 agcatatgca gccttcacat gccttcccag aggacttccg ggcacgttcc ggggccgggc
    12661 cccgggtctg cggtcgtctt cagccgtctg cggccgtctt cagccgtctt cagccgcctg
    12721 gagtcgcctg gagtcgcctg gagtcggctg cggtcgtcct ccccacccga tcgccttgcc
    12781 cggggcggcg gacggagccc acactgatcg tccggaaccg agggggcgtc atgaccgagc
    12841 acggaccggc cgatccggcc gacccgtccg gtttcggggc gctgctgcgc gaactgcgca
    12901 cccgcgccgg gatcaaccag cagaccaccg ccacccgggc cggactcagc gcccgggccc
    12961 tgcgcgacct cgaacacggc cgggtccggc ggccccgcgc acgcaccgtc caccggctcg
    13021 ccgacgcact cgccctgacc accgaccagg ccgccgcgct gcgcaccgcc gccacccggg
    13081 acgaccacgc ccccgggacc ggccgcacca ccctgctgct gctcggcccg ctgctgctgc
    13141 gccgcggccg cgacaccgtc ccgatcggca gccccaccct gcaccgcctg ctcggcctgc
    13201 tcgcactcac ccaccccgcc gccgccaccc ggcaggagat caccgacacc ctgtggccgg
    13261 ccggcccgcc cgcatcgcag cagagcctgg tgcacaccca cgtcagccga ctgcgccgcc
    13321 tgctcagccc cgacgacccg gacgaccccg cggccggcgt ggtccgcacc cccaccggct
    13381 accggctcgg cctgccccgg caccggaccg acctcggccg cttcgacgac ctgctggccc
    13441 gcaccacctg cctgtggcac gcccccgacc cggacgccgc ccaccaggac ctcacccgcg
    13501 ccctgcggca ctggcgcggc cccgtcctcg ccgacgccga ccccgccctg cgccggcacc
    13561 ccgccgcggt cgccgccaac gaacgccgca tccgcgccgc cctgctgcac gccgacaccg
    13621 ccctgctgct gcgccgcccc gaccactccg tcccgctgct gcgggaactc gcccacaccg
    13681 aaccgctgca cgaggggctg cacgcccggc tgatcctcac cctcgccgcg agcggccgcc
    13741 aggccgacgc cctcgacacc tacacccggc tgcgcactcg cctcgacgag gaactcggcg
    13801 tcacccccgg ccccgaactc cacgacgccc acctacgcgt cctacgcggc ctaccggggc
    13861 ccaccgccac gcggcccgca ccgcgcgcca ccggggagca ctggccgctg ccgcataccc
    13921 cggacgcccc ggacgccccg aacgctctcg acgcccaacc gcgcgtccta ccggggccca
    13981 ccgccgggtg gcctccacca cgtgctgccg gggagcacca gtcgctgccg cacaccccga
    14041 acgccccgaa cgccccgggt atcccgaaca ccctcggcgc cttcccgaag cctgcccaac
    14101 tcccgcccac caccggaccg ttcgtcgggc ggcaccggca gctgagcgcg ctcgacgcgc
    14161 tgctcccggc cgaccccgac cacctcgacc accccggtga gccggccgcc cgcccgccgc
    14221 tcctcgtggt ggtcggcccg cccggcatcg gcaagagcgc cctcgccgcg cactgggcac
    14281 accggcaccg cgaccgcttc ccggacggcc agctcttcgc cgacctgcgc ggccactccg
    14341 ctcggcccgc accgcacccg gacgaggtgc tggcccgctt cctgcgcgcc ctcggcaccc
    14401 cgcccgaccg gctgcccgcc gacccggacg aggccgccgc gctctaccgc accctgctcg
    14461 ccgaccgccg cctactggtc ctcctcgacg acgcccgcga cgccgaacag gtccgcccgc
    14521 tgctccccgg cgcccccggc tgcgccgtcc tggtcaccgg ccgcacccgg ctcaccggcc
    14581 tggtcgccgg tgacggcgcc cgccgcctca ccctcgaccc gctcgacccc gccgagggcg
    14641 ccctgctgct cggcagcgtc ctcggcccct gccgggtcgc cgccgaaccg gccgccgccc
    14701 accgcctggt ccgggcctgc ggcggcctcc ccctcgccct gcgcctggcc gccgccgacc
    14761 tgaccacccg caccaccgcc ctcgccgact acgcccccgc ccaccccgac gccgcccatc
    14821 ccgacgccgc cctgctcgcc cggctcgacc tcgccgacga cccgcgcacc ggcctgcgcg
    14881 ccgccttcgg ccactcctac cgcgtcctcc ccgcccccgc ccgccggatg ttccgcctgc
    14941 tcggccgggc ccccgccgcc gggctcaccg ccgccaccgc caccgcgctc gccgccaccg
    15001 gccccaccga gaccaccgcc ctactggacc gtctcgccga cgcccacctc gtccgggagg
    15061 aaccccccgg ccactaccgg ctgcccggcc tgctccaccc gtacgcggcg gggctggcgg
    15121 cggagggcga tgaggggtgc ggcggggggt gcggtgatgg cggctcgggg gcggttgacg
    15181 tcaatccatt gattgacgct catcagcagt ttggcggcga tcaatggatt gacgtcgagc
    15241 agccgcccac catcagcgga ttgaccggtc gtcagcatcc gaacgcgacc gccacccgag
    15301 tctgcgacgc ggaacccgcc gaagccaagc acgagttgac gcaccgcccg ctcatacccg
    15361 ttgcgcccgt cccgccccgc gacctggcgt ccggtgggtc cgacgggcgc ggcggcccgc
    15421 accccgacga catcaccgtg ctgggcctga tctgctggaa gctcggccgt ctgcccgagg
    15481 ccgccgagca cttcacgcag gccgcccgcg tcctcgccac cggccccgcc accaactccg
    15541 gccccggccc tgcccccgcc accagctccg gccccgccac cgccaccgcc accggctccg
    15601 gtcacagcgg cggggcgagc gaccgggagg ccatcgcccg gaccaacctg gccgtcgtgc
    15661 agcgggcgct cggacggccc ggggaggcga tccgggggat cggcgaggcg ctgccggtgc
    15721 accggtggca ccgcaaccgg ttcagcgagg ccgtcgcgct gagctgcctc tcccgtgccc
    15781 acaccgacct cggcgaccac gccaccgggc ggctgctggc ccacagcgcg ctcgccgccg
    15841 cccgggccgg gcgcagccgg gcgctggagg ccggggcccg gctcgccctc gccgactcgt
    15901 acctccgcgc ccaccgcccg gccgaggcga cggccgcgta ccgggaggcg ctgcggtcgg
    15961 ccgaggcctc gggcgaccgg cacccgcagg ccgccgccct ggcggggctg gccgccgccc
    16021 tgatcgaaac cgatccgcgg gccgcactgc gcaccgccga acgcgccctg gcgctggccc
    16081 gcgcagccga gtaccgggtg ctcgaaggcg acgcgctcac cgtcctggcc cgcgtccacg
    16141 tccggctgtg cgagccgcac gccgccctgg ccctcggcgc cgacgcgctc gccctgcacc
    16201 gggcgaccgg ccaccgcccg ggcgagaccc ggacccggct cgtcctggcc ctggccgccg
    16261 ccgcgctcgg tgccgacgcc gacgccgtcc ggcaccgccg ggaggccctg ctgctcgtcc
    16321 gggcgacggg cggaaccccg ccgcgctgac ccggaagttc cgcggaactt ccgccccgcc
    16381 gcatcaccgc agctcagcgc acccgcagcg cccgttcctc cttccggttc cgctccggcc
    16441 gatcgcacag cccggctcct tacggtggtc gcacctcacc cgcaccggac ccagaggtga
    16501 caccttgagc cgttacgacc gactcgcccg cacgccctcc gtgcgccgcg tccagcagga
    16561 aatgggcagc gccgccgcgg ccgagcgccg gctgcgcacg tccgacgacg cgcccgacga
    16621 cagacccgac gacgggcccg aaccgctcag cgccgccgcg gcggccttcg tccaggggct
    16681 cgacggcttc ctgttcgcga cggtcaacga ggacggctgg ccgtacatcc agcaccgcgg
    16741 cggcccgccc ggcttcgtcc acgtgctgga cccgtacacc ctcggctacc tcgacgtgcg
    16801 cggcaaccgg cagtacctca ccaccggcaa cctgcgcggc ggggacggcc gggtcgccct
    16861 gttcttcctc gaccacgccc ggcaggcccg gctgaaggtc ttcggccggg ccaccgccgt
    16921 ccccgccgac cgggacccgg acctcgcccg gcggctcgcc accccgcgca ccgacggccg
    16981 ggtcgagcag ctcgtcacca tcagcgtcga ggcgcacgcc tggaactgcc ccaaccacat
    17041 caccccgcgc ttcaccgagc gcgaactcgc cgacgtcctg gacccgatcc gcgaccggct
    17101 ggcccggctg gagcgggaga acgccctgct gcgcgccgag ctcgccgccg ccaccggcgc
    17161 gcacccctcc tcccgaccga aggactgatc ccgccgtgcc caccggcctg accgaccacc
    17221 ccgcggccgc ggccgcgacc gcccccggac cggccatctg gtcccgcaac ttccgccgct
    17281 acttcaccgc ccgcagcgcc ggtctgctca gctgggcgat gctcccggtc gccgtctcgg
    17341 ccgggctgct ctcggccggc cacggcctgg acaccgcggg ctacgcgatg gccttcctgg
    17401 tggccccgtt cgccgggctg gtgctgttcg gcggcgtcct cgccgaccgg ttcaccgccc
    17461 gccggatgat gatcgtcgcc gacctgacca acctcaccgc gcacgtcctg ctggccgccc
    17521 tgttctggca cggcgtcgac cggctctggc agctgtacgc cctgctcgcg gtggcgggca
    17581 ccgccaacgc cctgttccag cccggcgcgg cctcgaccgt cccgctgatc gcccgcgacg
    17641 tccagggcgc caacggcgtg ctgcgcacct cggaggcgat caccggcctc ggcggcccgg
    17701 cgctggccgg cgtgctggtc ggtttcgggt cgaccggctg ggtgatggcg ctgtccgcgc
    17761 tcgcctacgc caccagcgcg gcctgcctgt tcgcgctgcg cctcggcgcc gttcccgccc
    17821 cgcccgccgg gcactcgttc cggcacgacc tggccgtcgg ctggcacgag ttccgctccc
    17881 ggagctggct gtggggggtc atcctgatct ggatggtcta cgccgtcctc gcctgggggc
    17941 cgcagctctc gctcgccgcg ggcgtcgtcg tccccgccca cgggcccacc gcgttcggcc
    18001 tggtcaactg cgccctgggc gcgggcacgg tggccggcgg gctgctcgcc atccgctaca
    18061 agccccgccg ccccctcgcg gccggcgcgg tcgccatgtt cgcctatccg ctctaccccc
    18121 tcgccatcct gctgcacgcc ccggtctggc tgctcgccgc cgcccaggtg ctggtcggca
    18181 ccggcatcgg cgtctggggc gtgatgtggt cgaccgccgt ccagacccag gtgcccggcg
    18241 aggtcctcaa ccgcgtccat gcctacgagg tcgccggctc ggtgggcctc tacccgatcg
    18301 gctccgccct ggccgggccc gccgcgcacg ccttcggcac ctcccacgtc ctcgccgccg
    18361 gcaccctggt cgccctgctc acccccgccg ccctcctcct cgcccgcccc gtccgcaccc
    18421 tcccccgcat cccggaccgc cccgccgccc accccaacga cccatcaccg caccccggtt
    18481 gacccctccc cgcacccccg cccggacaac gaagaagccc caggtcgttg acctggggct
    18541 ctctgctgga gcgggtgacg agaatcgaac tcgcgctcta agcttgggaa tctcgacagc
    18601 cagtcagctt gcctggaccc tgaactgcac agatgccgcc agaaggctct ttacgacgcc
    18661 tatcgaaagg ctaactgttg accgctactg accgcctgtc ttcgcctcgt aagacacgga
    18721 tggggcacgc aaggagcgct acccgtcatc ccgcttccaa gatcaagctg agcgaactgc
    18781 ttcccggccc atcgctgtca cgacccgaac tgcaggtaag gacagacccc gcaggacgcc
    18841 ccgagagatc accccatggc catcacaggt gccgatcact ggactgccag actccatgac
    18901 agacgcgtgc tctgttttag ctggccaacg cggtcctaga caccatcttt cgatcaaaca
    18961 tcggcagaca aggcggctgg cagaccgcga gatggcgtct ccatctggac agagagtgac
    19021 tgagttaggc gcaatcggta gcgagaagcc tcaaacccga ccatacttct gaccaagcgc
    19081 cgcagggcgg cgtcgcgcac gttgccaggg ggtggcttgt gactggatct gaccgaaaga
    19141 agaccgtcgc cttttatgag attgtccgac caaaggactc gggcgaggca cgcatgtcta
    19201 atgttgactg gcaaacggtg ctggccaata ttggagacat tccccccgag cgccgcctat
    19261 atcgagacac cgaagatatt tatttcggcg agcccgtggt agcgggtgga cgcatgcatc
    19321 taggggtggc tcgacttcga gaccgcgaca ttcagcagat cgattgggtc catggaagaa
    19381 tcgatcatct gcagctagaa gagaatagaa gcatcgttga cacaaccgtc gtcagctttc
    19441 tgccttatgg aaatatcatc ggcgttctac aaggaacaat gtcagccccg cggccaagcg
    19501 cggttcagcg ttggctgaac agcatggact ctgggcttga ccgtgatatc gcagtagtcc
    19561 ctctcatcgg aagaaatgct cgcgagaagc taaagagggc cgaagcgatt aacttcttcg
    19621 aggtgagact ccgcccaggg ccggatcttc tggattcgga cgtagccggt ctcggagatt
    19681 tgtctcgccg ggctcatagg cataacccaa atgccctaat tacactaaca atgaagattc
    19741 ccaagcaggg acccttcagc cgaggaactc gacgctcgcg cggggaaagc caactgagag
    19801 aagatgttct aggttttatt tcccaatacg cgagcctggt gggcgagggc ggtgccgtag
    19861 accgggctat tgctcatgtc gtcctcccca acggcgacgg tgacctgatc gaagagaaga
    19921 tcaactttgt atctgatcac attactgccc agcggcaagt gatgatgcgg cggagcgagg
    19981 gtggagcccc ctggcatgag gcggcagtaa gagcgatcac gcaggtagct actgagtgtg
    20041 agcgcgagct gcgtgacgct gtcagtgccg tgccatagtc tccctgaagt cgattggggg
    20101 agtgatggct cgttgggcgc ggttcacgac atccatatac aacgcatggg gcgaacgccc
    20161 cacggtggac tgggtgcttg cggtggcgat tacgatctcc cacggtttca tttccggcaa
    20221 gcacttgcta gccgaaaact cggcagatca gcgcatgagc atctatgcga cggtcgcttc
    20281 cgtggcggcg attattggcg gatttggcac ggctgcaatt agtcaatatg cctccagctc
    20341 tggacggcga atgacgttta ttagagtcag gtttggccca agcctgcgcc gtaactgggt
    20401 tagcattctg gtttcgatgt cagaagtttc aattggatgc ctcgctgtca tgatttatga
    20461 ctctggggaa aatctgggcc gggcaggatg gctactggaa gccgttctgg tcctcggtat
    20521 tctgcgcaca attcgactga tttggctatt caggcttctg attgatgtat cggaccatga
    20581 tggagcgtct ggtggcggcc cggaagaagt ccgagttgtc aggagaaata atccgggaat
    20641 ctaagtcccg aagacttccg gaggagcgag tgcattaggg cggcggagcg gttttggccg
    20701 gtgtcctgcc tggtctgggg tcgagcatga tcggggggcc gtaagctgtt gcgactcggt
    20761 cagggctttt tgggcctgac cgcaatgtgg ccgagtggcc ccccgttctt gctcgacgcg
    20821 gggcccggtc ctggcaggtg ggtaaaatcg tggagccgtc ggccccagcc ccggcggagt
    20881 ttggggcccc tgctctctct gccgcccgtc cgccgacgcg gccggggcgc cgctggcgtg
    20941 gggcgaaggc aggagcgtcg gcgatcggcc aaggccgcgc tggcgcgctg tgcgcgcctt
    21001 gatgaagtag tggaactcgt aacagctcta ctgcctctgc cttttgatct actccccgcc
    21061 gggtacgagc tggccgtagg cggctg
//
