LOCUS       NZ_CP054919            21107 bp    DNA     linear   CON 31-JUL-2024
DEFINITION  Kitasatospora sp. NA04385 chromosome, complete genome.
ACCESSION   NZ_CP054919
VERSION     NZ_CP054919.1
KEYWORDS    RefSeq.
SOURCE      Kitasatospora sp. NA04385
  ORGANISM  Kitasatospora sp. NA04385
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Kitasatospora.
REFERENCE   1  (bases 1 to 8400742)
  AUTHORS   Zhang,B., Shi,J. and Ge,H.
  TITLE     Genome mining for natural products
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8400742)
  AUTHORS   Zhang,B., Shi,J. and Ge,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUN-2020) Institute of Functional Biomolecules, State
            Key Laboratory of Pharmaceutical Biotechnology, Nanjing University,
            No.163 Xianlin Avenue, Nanjing, Jiangsu 210046, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. v2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013364235.1-RS_2024_07_31
            Annotation Date                   :: 07/31/2024 08:11:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,532
            CDSs (total)                      :: 7,423
            Genes (coding)                    :: 7,206
            CDSs (with protein)               :: 7,206
            Genes (RNA)                       :: 109
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 218
            CDSs (without protein)            :: 217
            Pseudo Genes (ambiguous residues) :: 0 of 218
            Pseudo Genes (frameshifted)       :: 81 of 218
            Pseudo Genes (incomplete)         :: 153 of 218
            Pseudo Genes (internal stop)      :: 9 of 218
            Pseudo Genes (multiple problems)  :: 25 of 218
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:10:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2108037
            Orig. end                         :: 2129144
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054919.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21107
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="11"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21107
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21107
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11107](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11107
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            841..3285
                     /locus_tag="HUT16_RS09140"
                     /old_locus_tag="HUT16_09140"
     CDS             841..3285
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012381296.1"
                     /locus_tag="HUT16_RS09140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09140"
                     /product="DUF3488 and transglutaminase-like
                     domain-containing protein"
                     /protein_id="WP_176187202.1"
                     /transl_table=11
                     /translation="MTTRAKLTLCAALATALAALCLSPLFQDAFALAPHGLLMVAVAAG
                     AGAGLRALPLPRALVPPLQLVVVLYVLMLTTVQSSMSAGLLPGPGALDALSSLLSRGGT
                     DIQAYAIPAPATDGLRLIVVGSVALVAVLVDALAVTYRRAAAAGLPLLALYSVAGGLAE
                     SPGGMWLWFLFAAAGYLALLYTEGQDRLTRWGRVFHGTGRSAVALSNGGRRIGVIALAV
                     AVLVPALAPAVGGGLFDSLGGHHGEGTGNGNGGNDERSLNLVVALTANLRSSDDTELLT
                     FSTDSPDADQLYLRIAELSEFNGQEWVAGEQNPQPLPSSMPAPEGLGLNLPTTSVRTNI
                     TVSDRLSTTWLPMPYPMSWVELPNGSNWRFDPVGRTVSGVNGQKSKGLSYTVGSVAVNA
                     TAAQLRGAGAPPADVSKRYLGLPPNLPSVVADTAKDVTKGKTTPYDQAVALQQYFTSGG
                     FTYNTKIDSRTGPDAIAKFLQDKEGFCVHFAATMAAMSRSLGIPARVAIGFTPGSGNGT
                     DRVVRSSNYHAWPELYFNGYGWMRFEPTPNRGSAPLYSVQQTAPSSAPSTAPSSAAPSA
                     QPSAQPSASSDCPPQQHRPGECGDEAALVEHRTTTTPWWESWPVLVAVLGGVLLLAALA
                     FPMLWRTRLRRRRLGAGRHLSGADGPRLTDEQVLAAWAELVDSAWDLGIPPDDARTPRN
                     AVRRLAEDARLDADSAAAAGRVALATERVMYARESDAPAQLGGDVRAAREALRVRATRT
                     RRLRALLLPASAVRLWWRAQDRAAARRERTAERMAAVRAALAGPFRRLGRLGRLGRKKK
                     DG"
     gene            complement(3485..3862)
                     /locus_tag="HUT16_RS09145"
                     /old_locus_tag="HUT16_09145"
     CDS             complement(3485..3862)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135277.1"
                     /locus_tag="HUT16_RS09145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09145"
                     /product="DUF3040 domain-containing protein"
                     /protein_id="WP_176187204.1"
                     /transl_table=11
                     /translation="MPLSEHEQRLLEQMERALYAEDPKFASALEGTGLHTYTRRRVYLA
                     VAGFVAGIALLMGGLVAQVIWVSVVGFLVMLGCAVLAVTAWRRGPAGHGPRQSAGPRRK
                     SGVVDRMEQRWQRRRDEQSGL"
     misc_feature    3966..3979
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.41"
                     /tool="antismash"
     misc_feature    3973..3986
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.11"
                     /tool="antismash"
     gene            complement(4093..4845)
                     /locus_tag="HUT16_RS09150"
                     /old_locus_tag="HUT16_09150"
     CDS             complement(4093..4845)
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090237.1"
                     /locus_tag="HUT16_RS09150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09150"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_176187206.1"
                     /transl_table=11
                     /translation="MYPTRPRSALRTAVVWEVVREALERRSAELGRPVLEVVDTGGGTG
                     NFAVPVARLGHRVTVVDPSPDALFALERRAAEAGVTELVRAVQGDTQTLPELVPAGSVD
                     AVLCHGVLEVVDDPAEALGNLVATLDKGGLVSLLAANRNGAVLARAVAGQFTEARTALD
                     APDGRWGAGDPMPRRFTGEQLDALATGAGLRVASVHGIRVFADLVPGVLVDTEPGALDA
                     LLKLELAAAEQPAFHAVATQLHLLAEAI"
     gene            complement(4953..5453)
                     /locus_tag="HUT16_RS09155"
                     /old_locus_tag="HUT16_09155"
     CDS             complement(4953..5453)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135279.1"
                     /locus_tag="HUT16_RS09155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09155"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_254897724.1"
                     /transl_table=11
                     /translation="MTISRPEPVVRPAVDQPAVEQPTLPASRGSDVHPVLRRGSAAPAA
                     LELLRHAHRTLVHARGRQDPLERYATAHLAALRATAAVLAVRGRPVRHPRRRQAIRPAW
                     ELLPEVAPELAEWAAYFAAGARRRAAAEAGIAGAAGERDADDLIRNTALYLRIVERILA
                     LHP"
     misc_feature    complement(5587..5602)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.24"
                     /tool="antismash"
     gene            5936..6547
                     /locus_tag="HUT16_RS09160"
                     /old_locus_tag="HUT16_09160"
     CDS             5936..6547
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557093.1"
                     /locus_tag="HUT16_RS09160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09160"
                     /product="DUF4126 domain-containing protein"
                     /protein_id="WP_176187208.1"
                     /transl_table=11
                     /translation="MGAVPLIFTSGWASGINAYAVVLLLGLFGRFGGADSVPPVLGRTD
                     VLLAAGALFLCEAVLDKIPYVDSLWDAVHTVVRPVAGATVGALLAAHDPGSLGEVAAGA
                     VGGTTALLSHCVKAGLRMAANTSPEPASNVLLSLAEDLSVAGLVTLAIFHPWLAASAAA
                     VLLALGVLLVWFAVTRIRRFWLRRRERRARRRAGGAVAAG"
     misc_feature    5972..5985
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.74"
                     /tool="antismash"
     gene            6599..7987
                     /locus_tag="HUT16_RS09165"
                     /old_locus_tag="HUT16_09165"
     CDS             6599..7987
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003989638.1"
                     /locus_tag="HUT16_RS09165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09165"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_176187209.1"
                     /transl_table=11
                     /translation="MARIIVVGAGMGGLAAASRLATLGHRVTVLEAAGTHGGQVGHHRR
                     EGFGFDTGPGLLALPAVYRDLALKTGREPLEQLVALRPVDPESRHLFPDGTELLLPNAS
                     RDGVVRALDAAFGAGAGARWGELVNRGRTVWEATRRPLLEEPRPAVDPADPYPVPPRRG
                     LSRLLPRGRHTLADAARELGGGPGPAALLGEYALRYGLDPRTAPASATVLPYMEQSFGV
                     WYVDGGLRALADAVFERCGKRGAEFRFDTPVRALERDGGRVVGVRTDAGVLTADAVLCS
                     VPGLGGAGPAAPAPGRFTVLLALDGARPAGTAHRTVVHAADGAAEARAVFTDGVLPDRP
                     TVQVLRPDDPSLVPGPDAEAAVLTVTVPAGLTLGDAERDAYAGELLAHLAASGLDLRPR
                     LRWRETRLTASVPPPSLAGGHLAPANEPGPPGLYLIGAHAHPGGGLARVGMSASITAGL
                     LGPA"
     gene            complement(7995..8717)
                     /locus_tag="HUT16_RS09170"
                     /old_locus_tag="HUT16_09170"
     CDS             complement(7995..8717)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUT16_RS09170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUT16_09170"
                     /product="hypothetical protein"
                     /protein_id="WP_176187212.1"
                     /transl_table=11
                     /translation="MGIGYLLLYGALALVALWLTAELLLQNRAPLHWRALALLGFLGVV
                     AGMRASSVPVIVAGAAGFGLGQLMVTGAVRRGRPVGWSLRRSDGRLPGSLAKVPLLAAA
                     TGGTAAAAAAPEPVVPVGEVGPVEDEPYEAHDPYAGQFAGYEEFQQLDAGVYADDQSAY
                     QVPQQPQYGYVQQQDYGYQQQYVPQQPQPQPQLQLIGYDQYGQPVYQDPYTQQQYQQPY
                     VPQQQPQQDQNWYYQQQY"
     gene            complement(8881..9795)
                     /gene="metF"
                     /locus_tag="HUT16_RS09175"
                     /old_locus_tag="HUT16_09175"
     CDS             complement(8881..9795)
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135283.1"
                     /locus_tag="HUT16_RS09175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09175"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_176187214.1"
                     /transl_table=11
                     /translation="MALGIPTTRNDRAQTVRDLLAAGDRSFSFEFMPPRNEEAERKLWD
                     AIRRVECLEPNFVCMTYGAGGSSRGRTVDLVGRIATETTLTPVAHLTAVDHSVAELRNI
                     IGQYADQNVRNVLAVRGDPPGDPLGEWVRHPEGVTYAAELVELIKGIGDFCVGVAAFPQ
                     MHPRSENWDEDIRHFVAKCRAGADYAITQMFFEVEDYLRLRDRVAAAGCETPIIPEIMP
                     VTNSRQLVRFPQLSGSAFPDDFRRKLEAVVDDPAAVRAVGLEHATTMAERLLAEGAPGL
                     HFITLNHSTSTLEIYQNLGLHTR"
     misc_feature    9860..9874
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.07"
                     /tool="antismash"
     misc_feature    9974..9988
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            10001..11107
                     /locus_tag="HUT16_RS09180"
                     /old_locus_tag="HUT16_09180"
     CDS             10001..11107
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135284.1"
                     /locus_tag="HUT16_RS09180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09180"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_176187216.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.5e-44, bitscore:
                     150.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSSIRLPRNPVDAEDVRDRVNRTLGTFMVERAALLSGISDQLGP
                     VSDALRDFLLDGGKRLRPAFCYWGWRAAGGAADEPGIERAAAALELLQASALVHDDLMD
                     RSDTRRGLPAVHRRFENLHRAGGWRGDREQYGASAAVLLGDLLLIWCDELFQRSGLPTA
                     AVSAAKPAFDLMRTEVMLGQYLDVLEPVAGDSTDGGAIDRARTVLHYKSAKYTIERPLQ
                     VGALLAGAAPGLVEALGNFGLPLGEAFQLRDDLLGVFGDPAVTGKPAGDDLREGKRTLL
                     VAHAMRGLGPADAAHLDARLGAPGLDAGEIADLRDLITLSGAPDLVEARIDALLAEALD
                     ALDAAPIADGPTREVLRALADAATVRKY"
     gene            complement(11114..11779)
                     /locus_tag="HUT16_RS09185"
                     /old_locus_tag="HUT16_09185"
     CDS             complement(11114..11779)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018384160.1"
                     /locus_tag="HUT16_RS09185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09185"
                     /product="VanZ family protein"
                     /protein_id="WP_176187218.1"
                     /transl_table=11
                     /translation="MEPLAPPARRTRRAALLVPALLAAAAVAFLAQRPLGRGHRAGWNG
                     WVGTVNGIVFLAAAALPAAVLAAWLLARRRRAAGVEPGWARRSALAEVGAVYGTAPWVW
                     MILLPGADPGGPRRRVNLVPLHDIAEVVAAGPPATAVAQIGGNLLVFAALGFLAPVRFA
                     ALASVRRVLALGAACSVLVELAQYVLRLDRVSSVDDVLLNAGGAALAALAARRWWRRA"
     gene            complement(12022..12669)
                     /gene="thiE"
                     /locus_tag="HUT16_RS09190"
                     /old_locus_tag="HUT16_09190"
     CDS             complement(12022..12669)
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135286.1"
                     /locus_tag="HUT16_RS09190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09190"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_176187220.1"
                     /transl_table=11
                     /translation="MTAAPTARQRLADARLYLCTDARRAQGDLPEFLDAVLAGGVDVVQ
                     LRDKALEAKQELEHLEVFADAARRHGKLLAVNDRADVAYGARPDVLHLGQDDLPVAVAR
                     RILGEDVLIGRSCHAEDEVDTAFTEPGVDYFCTGPVWPTPTKPGRPAPGLDLVRHAAAR
                     RPERPWFAIGGIDQDNLQQVLDAGATRIVVVRALTAAEDPGAAAAALAARLR"
     gene            complement(12666..13031)
                     /locus_tag="HUT16_RS09195"
                     /old_locus_tag="HUT16_09195"
     CDS             complement(12666..13031)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606129.1"
                     /locus_tag="HUT16_RS09195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09195"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_033216844.1"
                     /transl_table=11
                     /translation="MSEIDPKIDALVPAWLYLPDISERWGVVITEVRDMVRNRTLLAVR
                     RGPNKSLQVPADFIEDDGPVKHLVGTLTVLRDCGFSDQEILEWMFTEDDSLPGSPIQAL
                     RENRGTEVKRRAQAMAL"
     misc_feature    complement(13008..13022)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.74"
                     /tool="antismash"
     gene            complement(13048..14253)
                     /locus_tag="HUT16_RS09200"
                     /old_locus_tag="HUT16_09200"
     CDS             complement(13048..14253)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135288.1"
                     /locus_tag="HUT16_RS09200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09200"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_176187222.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.2e-56, bitscore:
                     190.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGVAELRATDRVVVVGAGIAGAQAALNLRQGGWRGPLALVGEEP
                     HLPYDRPPLSKDVLLGKADATAFEIDWHGLDVELLTGRRATGLDDGVLRTDRGELRYDA
                     LVIATGAAPRTLPHLPGARTLRTVDDARALRAALTPGRRTVLVGAGWIGAETATVARGL
                     GCEVTVVEAAATPLAGALPAELGALMADWYAAAGVELRCSAAVAGAAAGGVLLTDGTHL
                     PADEVVVGIGARPATDWLADGPLALDPDGTIPVDDRLRTALPGVLAAGDCTSYPSARSG
                     TRLAVQHWDHALHSGAAVAASLLGTLDAPYDPVPYFWSEQFGRTVQYAGRHAGADHLLW
                     RGSPSDPDWTVLWLRDGVPVALLAVDRPRDLAQGRRLIERGTALDPARAADPAVQLKAA
                     AR"
     regulatory      14330..14443
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(14399..14412)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            14438..15592
                     /gene="thiO"
                     /locus_tag="HUT16_RS09205"
                     /old_locus_tag="HUT16_09205"
     CDS             14438..15592
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010471237.1"
                     /locus_tag="HUT16_RS09205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09205"
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_254897725.1"
                     /sec_met_domain="DAO (E-value: 8.6e-64, bitscore: 215.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHSRALDVLVVGGGIIGLGVAWRSAQRGLAVALVDPWPGGGAAR
                     VAAGMLAPVTELQYGEEPLLRLGMASNERYAAFAAELTELTGLDTGYRATGTLAVALDS
                     DDREELRELHAFHGRLGLASQWLTGRECRRLEPMLAPGVRGGLHVAGDHQVDGRRLAAA
                     LVVACERAGVVFHRAEAAELLVEDGRAAGVRLSTGERVAAGRTVLAAGSRSHLLPGLPA
                     GVLPAVRPVKGQVLRLRMPTAHGPFLSRNVRAVVRGQHLYLVPRADGELVVGATTEELG
                     HDTTVTAGGVYELLRDAHELVPGITELPLLEIGAGLRPGSPDNAPLLGPTALDGLAAAT
                     GHYRNGVLLTPVTADLLADYLATGELPPLAADFTPDRFTPKVPA"
     gene            15589..15798
                     /gene="thiS"
                     /locus_tag="HUT16_RS09210"
                     /old_locus_tag="HUT16_09210"
     CDS             15589..15798
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608023.1"
                     /locus_tag="HUT16_RS09210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09210"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_014135290.1"
                     /transl_table=11
                     /translation="MNTIALTVNGEPRTLPAATTLDVVVAEVSAANTGVAAAVNEAVVP
                     RSSWPATALGEGDRVEILTAVQGG"
     gene            15802..16593
                     /locus_tag="HUT16_RS09215"
                     /old_locus_tag="HUT16_09215"
     CDS             15802..16593
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135291.1"
                     /locus_tag="HUT16_RS09215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09215"
                     /product="thiazole synthase"
                     /protein_id="WP_176187226.1"
                     /transl_table=11
                     /translation="MADDALVIAGTTFSSRLIMGTGGAPSLEVLEQALKVSGTELTTVA
                     MRRVDTATQGSVLEVLSRNGIRVLPNTAGCYTAGEAVLTARLAREALETDWVKLEVIAD
                     ERTLLPDPIELLDAAETLVDDGFTVLPYTNDDPVLARKLEDVGCAAIMPLGSPIGSGLG
                     IRNPHNFQLIVEAANVPVVLDAGAGTASDVALAMELGCSAVMLASAVTRAQDPVLMAEA
                     MRKAVEAGRLAHRAGRIPRRYYAEASSPTAGLADTRERPAF"
     gene            16727..18463
                     /gene="pknB"
                     /locus_tag="HUT16_RS09220"
                     /old_locus_tag="HUT16_09220"
     CDS             16727..18463
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF033483.0"
                     /locus_tag="HUT16_RS09220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09220"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_254898274.1"
                     /sec_met_domain="Pkinase (E-value: 3.5e-50, bitscore:
                     169.5, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLDDPLHGVLLDGRYRIEQRIAVGGMATVYRGTDTRLDRTVALK
                     LMHPSLIGDADFTARFIREAKAVARLAHPNVVNVLDQGADPRAVFMAMEYVPGRNLRDV
                     LRDRGALSVRAALDVLEPVLAALGAAHRAGLVHRDVKPENVLITDNGMVKVADFGLVRV
                     LEGGDATGASATETGQLLGTVSYLAPEQIRQEPTDQRVDVYAAGILLYEMLTGAKPHTG
                     EHAAQVMYRHLHEDVPAPSLTAPAVGPELDAIVAAATSRDPQARPWDAVELLAAVQRAR
                     RSLPVEQLDAEPPASTRPTPRYSPGEATAVLEQLPPLERTSVLEVPPELLPPVRPVVND
                     DPPRGRPRRSPRSAFGRHPAAWSAVLVALLLVVGGVTYALSSAVYATVPSVLGQNREQA
                     AATLDRQGLHGSFSEQFSESVPNGSVISTDPGVGAKVRKSDGVKVLLSRGPERVAVPDV
                     TGRPQADAAKALGDARLTAGTSREEYSDTVPKGSVISTDPAAGSSQSPGSPVALTVSKG
                     MHVVPDVKGMGKEDASKALQDAGFVPEIAGLIPLGKVTGQSPAANTPAKQGSTVTITIS
                     LF"
     gene            complement(18481..19119)
                     /locus_tag="HUT16_RS09225"
                     /old_locus_tag="HUT16_09225"
     CDS             complement(18481..19119)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016435820.1"
                     /locus_tag="HUT16_RS09225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09225"
                     /product="sulfite oxidase-like oxidoreductase"
                     /protein_id="WP_176187230.1"
                     /transl_table=11
                     /translation="MGTMGQREPEQQPTTDPRLPPGQRPQRGWPVLHYGPVPRFKPQSW
                     DFQVFGATADAEKARWDFAGFHALPKTTVRGDLHCVTKFSMLGNEWTGVAAKTVLDLVP
                     PDPSVTHVMVWAEYGYSANLRLADFADPSTVLATHHDGRTLTLEHGFPVRLVVPHLYAW
                     KGPKWVRAVEYMRADRRGFWEERGYHNLADPWREQRYSYQEQPGDGPLR"
     gene            19410..19889
                     /gene="bfr"
                     /locus_tag="HUT16_RS09230"
                     /old_locus_tag="HUT16_09230"
     CDS             19410..19889
                     /EC_number="1.16.3.1"
                     /GO_function="GO:0004322 - ferroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /GO_process="GO:0006879 - intracellular iron ion
                     homeostasis [Evidence IEA]"
                     /GO_process="GO:0006880 - intracellular sequestering of
                     iron ion [Evidence IEA]"
                     /codon_start=1
                     /gene="bfr"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005478270.1"
                     /locus_tag="HUT16_RS09230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09230"
                     /product="bacterioferritin"
                     /protein_id="WP_176187232.1"
                     /transl_table=11
                     /translation="MQGDPEVIEFLNEQLTAELTAINQYFLHAKMQENFGWTKLAKYTR
                     HESFDEMKHAEILTDRILFLDGLPNYQRLFHVRIGQTVKEMFEADRQVEVEAIDRLRRG
                     IVVMRAKNDVTSANIFEAILEDEEHHIDYLDTQLELLDKLGEALYIAQLIEQPES"
     gene            complement(19930..20178)
                     /locus_tag="HUT16_RS09235"
                     /old_locus_tag="HUT16_09235"
     CDS             complement(19930..20178)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_BFD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135296.1"
                     /locus_tag="HUT16_RS09235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT16_09235"
                     /product="bacterioferritin-associated ferredoxin"
                     /protein_id="WP_176187234.1"
                     /sec_met_domain="Fer2_BFD (E-value: 4e-13, bitscore: 48.3,
                     seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYVCMCHAVTEAQVKQKIDEGANTPRQIAQGCKAGTDCGSCVRRI
                     QALLGEHGARPCPTARLAERLGLADPATAPAVAPKAA"
     misc_feature    complement(20206..20224)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 20.83"
                     /tool="antismash"
     misc_feature    20308..20323
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.79"
                     /tool="antismash"
     misc_feature    complement(20348..20362)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.35"
                     /tool="antismash"
     misc_feature    20795..20808
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.7"
                     /tool="antismash"
     misc_feature    20872..20886
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.26"
                     /tool="antismash"
ORIGIN
        1 ccgcgcgttc agcgccgcgg acgtgctgac cgtcgtcccg caggtccagg acctgccggg
       61 ggtccggctg cccggcgagt ccggcgggca gggcgactcc aacagccact ccctggcgct
      121 ggccggcgac gacgacgtca tcccgcgcga gtaccggcac ggcgacgacc tgcgccgggt
      181 gcactggaag tccaccgccc ggtacggcga gctgatggtg cgccgcgagg agcagccgct
      241 gcaggcccgc gccaccgtgc tgctggacac ccgggagacc gcgcaccgcg gttccggccc
      301 ggcgtcctcg ttcgagtggg cggtgtcctg cgccgcctcg gtcgcggtcg acctggtgca
      361 gcgcggctac cgcacccggc tgctcaccga caccggctcc tcggtgcccg acaccggccc
      421 cggtggcggc ggcaccagcg cggccgagtc ggtcggcatg ctgctggacg cgctggccgt
      481 ggtcgagcac tccgacggcg gcaccctggc ccgggccgag gaggtgctcc ggctcggcgg
      541 cgagggcctg ctggtggcgg tcgtcggcga gctggacgag gagcaggtgg agcggctggc
      601 ccggctgcgc cggcgcaccg gcggcgccgt cgtgctgctg ctggacaccg gcacctggtc
      661 gggcctgcgc cacctgctgc cggacagcgc ggacgagcag gtcgagagcc gcgtggcccg
      721 gctgcgcgag tccggctgga ccgtgctgcc ggtgcgggcc ggcgactcgc tgcccgccct
      781 gtggcgggcc gcggaccgca cccagaacaa caccgttccc taccgagacg aggtcggcgc
      841 ttgaccaccc gggccaagtt gacgctctgc gcggccctgg ccaccgccct ggccgcgctg
      901 tgcctgtccc cgctgttcca ggacgccttc gcactggccc cgcacgggct gctgatggtc
      961 gccgtcgcgg ccggcgccgg cgccggcctg cgcgccctgc cgctgccccg ggccctggtg
     1021 ccgccgctgc agctcgtcgt ggtgctgtac gtactgatgc tcaccaccgt gcagtcctcg
     1081 atgagcgccg gcctgctgcc cggcccgggc gcactggacg cgctctcctc gctgctcagc
     1141 cggggcggca ccgacatcca ggcgtacgcg atcccggccc cggccaccga cggcctgcgg
     1201 ctgatcgtgg tcggctcggt cgccctggtg gccgtgctgg tcgacgccct ggcggtcacc
     1261 taccgccggg ccgcggccgc gggcctgccg ctgctcgccc tgtactcggt ggccggcggc
     1321 ctggccgagt cgccgggcgg catgtggctg tggttcctgt tcgcggccgc cgggtacctg
     1381 gcgctgctct acaccgaggg ccaggaccgg ctcacccgct ggggccgggt cttccacggc
     1441 accggccgct ccgccgtcgc gctgtccaac ggcggccgcc ggatcggcgt gatcgcgctg
     1501 gccgtcgcgg tgctggtgcc ggcgctcgcc cccgcggtcg gcggcggcct gttcgacagc
     1561 ctgggcggcc accacggcga gggcaccggc aacgggaacg gcggcaacga cgagcgctcg
     1621 ctcaacctgg tcgtcgcgct caccgccaac ctgcgctcca gcgacgacac cgagctgctg
     1681 accttctcca ccgactcgcc cgacgcggac cagctctacc tgcggatcgc cgagctcagc
     1741 gagttcaacg gccaggagtg ggtggccggg gaacagaacc cgcagccgct gccgagcagc
     1801 atgcccgcgc ccgaggggct gggcctgaac ctgcccacca cctcggtccg caccaacatc
     1861 acggtctccg accggttgag caccacctgg ctgccgatgc cctacccgat gtcctgggtg
     1921 gaactgccga acggctcgaa ctggcgcttc gacccggtgg ggcgcaccgt cagcggcgtc
     1981 aacggtcaga agagcaaggg gctgagctac acggtgggct cggtggccgt caacgccacc
     2041 gcggcccagc tgcgcggcgc cggggcgccc ccggccgacg tcagcaagcg ctacctgggc
     2101 ctgccgccca acctgccgtc ggtggtggcc gacaccgcca aggacgtcac caagggcaag
     2161 accaccccgt acgaccaggc cgtcgcgctc cagcagtact tcaccagcgg cggcttcacc
     2221 tacaacacca agatcgactc gcggaccggg ccggacgcca tcgccaagtt cctccaggac
     2281 aaggagggct tctgcgtcca cttcgccgcc accatggccg cgatgtcccg ctccctgggc
     2341 atccccgccc gggtcgcgat cggcttcacc ccgggctccg gcaacggcac cgaccgggtg
     2401 gtgcgcagct ccaactacca cgcctggccg gagctgtact tcaacggcta cggctggatg
     2461 cgcttcgagc ccaccccgaa ccggggctcc gccccgctgt actcggtcca gcagaccgcg
     2521 cccagcagcg cgcccagcac cgcgcccagc agtgccgcgc cgagcgcgca gccctccgcc
     2581 cagccgtccg cctccagcga ctgccccccg cagcagcacc ggccgggcga gtgcggcgac
     2641 gaggccgcgc tggtcgagca ccggacgacg acgacgccct ggtgggagtc ctggccggtc
     2701 ctggtggccg tgctcggtgg cgtgctgctg ctggcggcgc tggccttccc gatgctctgg
     2761 cgcaccaggc tgcgccgccg ccgcctcggc gccggccgcc acctgtccgg ggcggacggg
     2821 ccgcggctca ccgacgagca ggtgctcgcc gcctgggccg aactggtcga ctccgcctgg
     2881 gacctgggca tcccgccgga cgacgcccgc accccgcgca acgcggtgcg ccggctcgcc
     2941 gaggacgccc ggctggacgc cgactccgcg gccgccgcgg gccgggtcgc cctcgccacc
     3001 gagcgcgtca tgtacgcccg cgagtccgac gcgcccgcgc agctgggcgg cgacgtccgg
     3061 gccgcccggg aggcgctgcg ggtgcgcgcc acccgcaccc ggcggctgcg cgcgctgctg
     3121 ctgcccgcct ccgcggtgcg gctgtggtgg cgcgcccagg accgcgccgc ggcccgccgg
     3181 gagcgcacgg ccgaacggat ggcggcggtc cgggccgccc tggccgggcc gttccggcgg
     3241 ctcggacggc tggggcggct cgggcggaag aagaaggacg ggtagccccg cggcccgccg
     3301 gaccgccgcg ccccggtggt ccggcgggct ggtcgtccgg cgggctggtc gtccggcggg
     3361 ctggtcgtcc ggcgggccgg cggatcgtcg gcccggcggc ccggcggccc ggacgggcgc
     3421 acgcgaaagg tccgcccggc gggggaactc ccccgccggg cggaccacgt tgtggtgggt
     3481 gctgctagag gccgctctgt tcgtcgcggc ggcgctgcca gcgctgttcc attcgatcga
     3541 cgacgccgga cttccggcgt ggtcccgcgc tctgtcgcgg gccgtgcccg gccgggccgc
     3601 ggcgccacgc ggtgaccgcg aggaccgcac aaccgagcat caccaggaac ccgaccacgc
     3661 tgacccagat gacctgggcg accaggccgc ccatgagcag cgcgatgcct gccacgaatc
     3721 ccgccacggc caggtagacc cgccgacggg tgtaggtgtg caggccggtt ccctcgagcg
     3781 ctgacgcgaa cttgggatct tcggcgtaca gcgctcgctc catctgctcg agcagtcgct
     3841 gctcgtgctc cgagagcggc acggagtcct cctactcgtc ggtcgcgggg cgaccggtcc
     3901 gccacccctg gctcgggcct gtgtggtcca tatgccccac cggtctggcc gtcatgctta
     3961 ccggctttac ccagatcata cggtccacgg ccgcggttcg gcgtggtcaa tcaggcgtgg
     4021 ctcgggccac cgctccggcg gcccgcaccc ctgcaacgag cggagggccc gcttggtgcc
     4081 ccccgcggcg gatcagatcg cctcggcgag caggtggagc tgggtggcga cggcgtggaa
     4141 ggcgggctgc tcggcggcgg ccagctccag cttgagcagg gcgtcgagcg cgccgggctc
     4201 ggtgtcgacc aggacgccgg ggacgaggtc ggcgaagacc cggatgccgt gcaccgaggc
     4261 gacccgcagc ccggcgccgg tggccagcgc gtccagctgc tcgccggtga agcggcgggg
     4321 catcgggtcc ccggcgcccc agcggccgtc gggggcgtcc agcgcggtgc gggcctcggt
     4381 gaactggccg gccaccgcgc gggccagcac cgcgccgttg cggttggcgg cgagcaggct
     4441 gaccaggccg cccttgtcga gggtggcgac caggttgccg agcgcctcgg ccgggtcgtc
     4501 gacgacctcc aggacgccgt ggcagagcac cgcgtcgacc gatccggccg ggacgagttc
     4561 gggcagcgtc tgggtgtccc cctggacggc ccggaccagc tcggtgacgc cggcctcggc
     4621 ggcccggcgc tccagggcga acaacgcgtc ggggctgggg tcgaccacgg tgacccggtg
     4681 gcccagcctg gccaccggca cggcgaagtt gccggtgccg ccgccggtgt cgacgacctc
     4741 caggaccggc cgtccgagct cggcggagcg ccgctccagc gcttcccgca ccacctccca
     4801 caccacggcg gtacgcagcg cactgcgggg acgagtcgga tacaaggcgg cacccctctt
     4861 ggcaggtctt ccacggcggg aacgcctcca ccttatccgc cgggatcgac cggccggggc
     4921 gcggcgcagc gccggacggc aggtaccgga cgtcaggggt gcagggccag gatccgctcc
     4981 acgatgcgca ggtacagggc ggtgttgcgg atcaggtcgt ccgcgtcccg ttcgccggcg
     5041 gcaccggcga tgccggcctc ggcggcggcc cggcggcgcg ccccggccgc gaagtaggcg
     5101 gcccactcgg cgagctcggg ggcgacctcg ggcagcagct cccaggccgg gcggatcgcc
     5161 tggcggcggc gcgggtggcg caccgggcgg ccgcggacgg cgagcacggc ggcggtggcg
     5221 cgcagcgcgg cgaggtgggc ggtggcgtag cgctccagcg ggtcctgtcg gccgcgggcg
     5281 tgcaccaggg tgcggtgcgc gtgccggagc agttcgagtg cggccggcgc ggcggagccg
     5341 cggcgcagca ccgggtggac gtcgctgccg cgggaggcgg gcagggtggg ctgctcgacg
     5401 gcgggttgat cgacggcagg acggacgaca ggctcaggac ggctgatggt catgggtctc
     5461 ccccgttcac tccggacctt gcccggaccg gtcggtccgc gcatgcatcc atcgtgaacg
     5521 gggggtctga caactcgggg tcccccgacc ccgttccagt cgtcccccac ggccggtctc
     5581 cccggattcc ccccaggggg aggggccggg ctccgccgcc ccgtgtcggc ggtgcccggc
     5641 ccccgttccg gccgttggtc gcgctccggg ccgtggtgtc gaccgtcgtt ccccctgaac
     5701 ccgacggtcg ggccccgagc gctccgggtg gctccgcccg gcggcggcct tcccggtgcc
     5761 caccactctg ccgtccgccg gggccgccgg gtatccgtgc gggtactcaa ccggtgatct
     5821 gagtacggat actcagccgc ccgccgttcg accgccctcc cccgccccgg gcccggcccg
     5881 gtacggtggc cgcgtcccgc ccgagggccg ggcggacgcg tcgaaggggg ccgccgtggg
     5941 ggccgttccg ctgatcttca ccagcggctg ggcgagcggg atcaacgcgt acgccgtggt
     6001 gctgctgctc ggcctgttcg gccgcttcgg cggggcggac tcggtgccgc cggtgctggg
     6061 gcgcacggac gtgctgctgg ccgccggggc gctgttcctg tgcgaggcgg tgctggacaa
     6121 gatcccgtac gtggacagcc tctgggacgc ggtgcacacg gtggtccgcc cggtcgcggg
     6181 cgcgacggtg ggcgcgctgc tggccgcgca cgacccgggg tcgctgggcg aggtcgcggc
     6241 gggggcggtc ggcgggacga cggcgctgct cagccactgc gtcaaggcgg gcctgcggat
     6301 ggcggccaac acctcgcccg agccggcctc gaacgtcctg ctgagcctgg ccgaggacct
     6361 ctcggtggcc ggcctggtga cgctggcgat cttccacccc tggctggccg cctcggcggc
     6421 ggcggtgctg ctggccctcg gcgtgctgct ggtgtggttc gcggtgaccc gcatccggcg
     6481 cttctggctg cgccgccggg agcgccgggc gcgtcggcgg gccggcgggg cggtggcggc
     6541 cggctagccc cggcgggcgg ggccgactag ggcccggggg cgcataggat cttctgccat
     6601 ggctcggatc atcgtcgtcg gcgcaggcat gggcggtctg gccgccgctt cccggttggc
     6661 caccctcggg caccgggtga cggtgctgga ggccgccggg acgcacggcg ggcaggtggg
     6721 gcaccaccgc cgggagggct tcgggttcga caccgggccg gggctgctcg cgctgcccgc
     6781 cgtctaccgc gacctggcgc tgaagaccgg gcgggagccg ctggagcagc tggtcgccct
     6841 gcggccggtg gatccggaga gccggcacct gttcccggac ggcaccgaac tgctgctgcc
     6901 caacgcctcc cgggacggcg tggtccgggc gctggacgcg gcgttcggcg cgggggccgg
     6961 cgcccgctgg ggcgaactgg tcaaccgggg ccgcacggtg tgggaggcga cccgccgccc
     7021 gctgctggag gagccgcgcc cggccgtcga cccggccgac ccgtacccgg tgccgccgcg
     7081 ccgcggcctg tcccggctgc tgccgcgcgg acggcacacc ctggcggacg cggcccgcga
     7141 gctgggcggc gggccgggcc cggcggcgct gctcggcgag tacgcgctgc gctacggcct
     7201 ggacccgcgc accgcgcccg cctcggcgac cgtgctgccg tacatggagc agtccttcgg
     7261 cgtctggtac gtcgacggcg ggctgcgggc gctggccgac gcggtgttcg agcggtgcgg
     7321 gaagcgcggc gcggagttcc gcttcgacac ccccgtgcgg gccctggagc gggacggcgg
     7381 gcgggtggtg ggcgtgcgca cggacgcggg ggtgctgacg gccgacgcgg tgctctgctc
     7441 cgtgcccggc ctgggcggcg ccgggcccgc cgcgcctgcg ccgggccggt tcaccgtgct
     7501 gctggcgctg gacggcgccc gcccggcggg caccgcgcac cgcaccgtgg tgcacgcggc
     7561 ggacggggcg gccgaggccc gcgcggtctt caccgacggc gtgctgccgg accgccccac
     7621 cgtgcaggtg ctgcggcccg acgacccgtc gctggtgccc ggcccggacg cggaggccgc
     7681 cgtgctgacc gtcaccgtgc ccgccgggct caccctcggc gacgccgaac gggacgccta
     7741 cgccggggag ttgctcgccc acctggccgc gtccggcctc gacctgcgcc cccggctgcg
     7801 ctggcgggag acccggctga ccgcctccgt cccgccgccc tcgctggccg gcggacacct
     7861 cgcgccggcc aacgagcccg gcccgcccgg cctgtacctg atcggcgcgc acgcccaccc
     7921 gggcggcggg ctggcccggg tcgggatgtc cgcctcgatc accgccggac tgctcggccc
     7981 agcctgacgg ggcgtcagta ctgctgctgg tagtaccagt tctggtcctg ctgcggctgc
     8041 tgctgcggga cgtacggctg ctggtactgc tgctgggtgt acgggtcctg gtagaccggc
     8101 tgcccgtact ggtcgtagcc gatcagctgc aactgcggct gcggttgcgg ctgttgcggg
     8161 acgtactgct gctggtagcc gtagtcctgc tgctggacgt agccgtactg gggctgctgc
     8221 gggacctggt aggcgctctg gtcgtcggcg tagacgcccg cgtcgagctg ctggaactcc
     8281 tcgtacccgg cgaactgccc ggcgtacggg tcgtgggcct cgtacggctc gtcctcgacc
     8341 gggccgacct cgccgaccgg gacgaccggc tccggggcgg cggccgcggc ggccgtcccg
     8401 ccggtggccg cggccagcag cgggaccttc gccagcgaac cgggcagtcg gccgtccgag
     8461 cggcgcagcg accagcccac cgggcggccg cgcctgaccg cgcccgtcac catcagctgg
     8521 ccgagcccga agccggccgc gcccgccact atcaccggca ccgaggaggc ccgcatcccg
     8581 gcgaccacgc cgaggaagcc cagcagcgcg agcgcccgcc agtgcagcgg ggcccggttc
     8641 tgcagcagga gttcggcggt cagccagagc gcgaccaggg ccagcgcgcc atagaggagc
     8701 aggtatccga tgcccatccc cgcaacctcc agacgccacc atcaccgcgc ggttgcgggc
     8761 gactgtacag cctccggacg gacaccacct catcccgggc acggccttct cgacgggcct
     8821 ggaccagcgc gtgcgcaggc ctccgccccg cgcggcggac tccccgccgc cggagccgga
     8881 tcagcgggtg tgcaggccca ggttctggta gatctccagc gtcgaggtgg agtggttcag
     8941 cgtgatgaag tgcaggcccg gggcgccctc cgcgaggagc cgctcggcca tcgtggtggc
     9001 gtgctccagc cccaccgcgc ggacggccgc cgggtcgtcg acgacggcct ccagcttgcg
     9061 gcggaagtcg tccgggaagg cggagccgga cagctgcggg aagcgcacca gctggcggct
     9121 gttggtgacc ggcatgatct ccgggatgat cggcgtctcg cagccggccg cggcgacccg
     9181 gtcgcgcagc cgcaggtagt cctcgacctc gaagaacatc tgggtgatcg cgtagtcggc
     9241 gccggcccgg cacttggcga cgaagtgccg gatgtcctcg tcccagttct ccgagcgcgg
     9301 gtgcatctgc gggaaggccg cgacgccgac gcagaagtcg ccgatgccct tgatcagctc
     9361 gaccagctcg gcggcgtagg tgacgccctc ggggtggcgg acccactcgc ccagcgggtc
     9421 gccgggcggg tcgccgcgca ccgcgagcac gttgcgcacg ttctggtcgg cgtactggcc
     9481 gatgatgttg cgcagctcgg ccaccgagtg gtcgacggcg gtgaggtggg cgacgggggt
     9541 gagcgtggtc tcggtggcga tccgcccgac caggtcgacg gtgcggccgc gcgaggagcc
     9601 gcccgcgccg tacgtcatgc agacgaagtt cggttccagg cactcgaccc ggcggatcgc
     9661 gtcccagagc ttgcgctcgg cctcctcgtt gcgcggcggc atgaattcga aggagaagga
     9721 gcggtcgccg gccgccagca ggtcgcgcac ggtctgcgcg cggtcgtttc tggtggtggg
     9781 aatcccgagt gccatgctgg caggttatcc gtcggcggcg cggcccggac aaacaacgtc
     9841 catctcctga gacgtcactt gagattttcg gccagccggt cgcgggcccg gtcgaaggcc
     9901 cccggcgggc ccggtcgcgg gccgccggag agcgggtgga acggcccacc ctgcgcggag
     9961 cgttaatctg actgtcagcc ccatcgatcc ggagtctcag gtgccctcct ccatccgcct
    10021 tccccgcaac cccgtcgacg cggaggacgt gcgcgaccgc gtgaaccgca ccctcggcac
    10081 gttcatggtc gagcgggcgg ccctgctctc cgggatctcc gaccagctcg ggccggtctc
    10141 cgacgcgctg cgcgacttcc tgctggacgg cgggaagcgg ctgcgcccgg cgttctgcta
    10201 ctgggggtgg cgggcggccg gcggcgccgc ggacgagccc gggatcgagc gggcggcggc
    10261 cgcgctggag ctgctgcagg ccagcgccct ggtgcacgac gacctgatgg accgcagcga
    10321 cacccgccgc ggcctgcccg ccgtccaccg ccgcttcgag aacctgcacc gggcgggcgg
    10381 ctggcgcggc gaccgcgagc agtacggggc gtccgcggcg gtgctgctcg gtgacctgct
    10441 gctgatctgg tgcgacgagc tgttccagcg ctcggggctg ccgacggccg ccgtgtcggc
    10501 cgccaagccc gcgttcgacc tgatgcgcac cgaggtcatg ctcggccagt acctggacgt
    10561 gctggagccg gtcgcgggcg actccaccga cggcggggcg atcgaccggg cccggaccgt
    10621 cctgcactac aagtccgcga agtacaccat cgagcggccg ctccaggtcg gcgcgctgct
    10681 ggccggcgcc gcccccggcc tggtcgaggc gctcgggaac ttcggcctgc cgctgggcga
    10741 ggcgttccag ctccgcgacg acctgctggg cgtcttcggc gacccggcgg tcaccggcaa
    10801 gccggccggc gacgacctgc gcgagggcaa gcgcaccctg ctggtcgcgc acgccatgcg
    10861 cggcctgggc ccggccgacg ccgcccacct ggacgcccgg ctcggcgcgc ccggcctgga
    10921 cgccggggag atcgccgacc tgcgcgacct gatcaccctc agcggcgccc ccgacctggt
    10981 cgaggcccgg atcgacgcgc tgctcgccga ggcgctggac gccctggacg cggccccgat
    11041 cgccgacggc ccgacccgcg aggtgctccg ggcgctggcc gacgccgcga cggtccgcaa
    11101 gtactgacgg gggtcaggcc cgccgccacc agcggcgcgc ggccagcgcc gccagcgcgg
    11161 ccccgcccgc gttcagcagc acgtcgtcga ccgaggagac ccggtccagc cgcagcacgt
    11221 actgggcgag ctccaccagc accgagcagg ccgcgccgag cgccagcacc cgccgcaccg
    11281 aggcgagcgc ggcgaaccgc accggggcga ggaagccgag cgcggcgaac accagcaggt
    11341 tgccgccgat ctgggccacc gcggtggcgg gcgggccggc cgcgacgacc tccgcgatgt
    11401 cgtgcagcgg caccaggttg acccggcggc gcggaccgcc cgggtcggcg ccgggcagca
    11461 ggatcatcca cacccacggc gccgtcccgt agaccgcgcc gacctcggcc agcgccgagc
    11521 gccgagccca ccccggctcg accccggccg cccggcggcg gcgggccagc agccaggccg
    11581 ccagcaccgc cgccggcagg gcggccgcgg ccaggaagac gatgccgttg acggtgccga
    11641 cccagccgtt ccacccggcg cggtggccgc ggcccaacgg ccgctgggcg aggaaggcga
    11701 cggccgccgc cgcgagcagc gcgggaacga gcagggcggc ccggcgggtg cggcgggcgg
    11761 gtggcgcgag gggctccatg cctgcacgga gggcgaaccg ggccgcccgg ttcccgcccg
    11821 ggggcctggc gcccccgcgt tccgccggag cggggacggc cgtgccgccc ggccgcggcg
    11881 acgggacggc cgcgcggggt tccggtcgcc ggcgggacct gccccgcaac cggatctctc
    11941 ccgtgctccg cttccgcccc gtgcggggtc cggcggggcg gggcgctcga ccggcggagg
    12001 agcgccccgc ccggagggcg cctagcgcag gcgggcggcc agcgcggccg cggccgcgcc
    12061 ggggtcctcg gcggcggtga gggcgcggac cacgacgatc cgggtggcac cggcgtccag
    12121 gacctgctgg aggttgtcct ggtcgatgcc gccgatggcg aaccaggggc gctcggggcg
    12181 gcgcgcggcg gcgtggcgga ccaggtcgag gccgggggcg ggccggccgg gcttggtggg
    12241 cgtgggccag accgggccgg tgcagaagta gtcgacgccg ggctcggtga acgcggtgtc
    12301 gacctcgtcc tcggcgtggc aggagcggcc gatcagcacg tcctcgccga ggatgcgccg
    12361 ggcgacggcg accggcaggt cgtcctggcc gaggtgcagc acgtcgggcc gggcgccgta
    12421 cgcgacgtcg gcgcggtcgt tgacggccag cagcttgccg tggcggcggg ccgcgtcggc
    12481 gaagacctcc aggtgctcca gctcctgctt ggcctccagg gccttgtcgc ggagctggac
    12541 gacgtcgacg ccgcccgcga gcaccgcgtc caggaactcg ggcaggtcgc cctgggcccg
    12601 gcgggcgtcg gtgcagaggt agagccgggc gtcggccagc cgctgccggg cggtgggcgc
    12661 ggccgtcaca gggccatggc ctgggcgcgg cgcttcacct cggtgccgcg gttctcgcgc
    12721 agggcctgga tcgggctgcc gggcagggag tcgtcctcgg tgaacatcca ctcgaggatc
    12781 tcctggtcgg agaagccgca gtcgcgcagc acggtgaggg tgccgaccag gtgcttgacc
    12841 gggccgtcgt cctcgatgaa gtcggcgggg acctggaggg acttgttggg gccgcggcgg
    12901 acggccagca gggtgcggtt gcgcaccatg tcgcggacct cggtgatcac cacgccccac
    12961 cgctccgaga tgtcgggcag gtacagccag gcggggacca gggcgtcaat cttcggatca
    13021 atctcgctca ctcccccagc ctaggcgcta tcgggcggcg gccttcaact ggacggcggg
    13081 gtcggcggcg cgcgccgggt ccagcgcggt gccgcgttcg atcaggcggc ggccctgggc
    13141 caggtcgcgc gggcggtcga cggcgagcag cgcgaccggg acgccgtcgc gcagccacag
    13201 caccgtccag tcggggtcgg acggggagcc gcgccacagc aggtggtcgg ccccggcgtg
    13261 ccggccggcg tactggaccg tccggccgaa ctgctcggac cagaagtacg ggacggggtc
    13321 gtacggggcg tcgagggtgc cgagcaggga ggcggcgacg gcggcgccgg agtgcagggc
    13381 gtggtcccag tgctggacgg cgagccgggt gccggagcgg gcggaggggt aggaggtgca
    13441 gtccccggcg gcgaggacgc cgggcagggc ggtgcgcagc cggtcgtcga ccgggatcgt
    13501 gccgtcgggg tcgagggcga gcgggccgtc ggccagccag tcggtggcgg ggcgggcgcc
    13561 gatgccgacc acgacctcgt cggcgggcag gtgggtgccg tcggtgagca gcaccccgcc
    13621 ggcggcggcg ccggccaccg cggcggagca gcgcagctcg acgccggcgg cggcgtacca
    13681 gtcggccatc agggcgccga gttcggcggg cagcgcgccg gccagcgggg tggcggcggc
    13741 ctccaccacc gtgacctcgc agccgagccc gcgggcgacg gtggcggtct cggcgccgat
    13801 ccagcccgcg ccgaccagca cggtccggcg gccgggggtg agggcggcgc gcagcgcgcg
    13861 ggcgtcgtcg acggtgcgca gggtgcgggc gccgggcagg tggggcaggg tgcgcggggc
    13921 ggcgccggtg gcgatcacca gggcgtcgta gcgcagttcg ccgcggtcgg tgcgcaggac
    13981 gccgtcgtcg aggccggtgg cgcggcggcc ggtgagcagc tcgacgtcga ggccgtgcca
    14041 gtcgatctcg aaggcggtgg cgtcggcctt gccgagcagg acgtccttgg agagcggcgg
    14101 gcggtcgtag gggaggtgcg gttcctcgcc gaccagggcg agcgggcccc gccagccccc
    14161 ctgccgcagg ttcagggcgg cctgggcgcc cgctatgccc gctccgacca cgacgacccg
    14221 gtccgttgcc ctcagctcag ccacgccgtc caccctaccc accgccgggt gtccgccccg
    14281 ggcccgcgcc ttcgggtgcg cggcggcccg gcgttaaggt gggggtgact tcacttcaca
    14341 cgggagcccg gtgcaccggg ctgagaggcg ggctgtggcg gcccgcgacc gtccgaacct
    14401 gatccgggtc atgccggcga agggagatcg agccgctgtg gcacattccc gcgcgttgga
    14461 cgtgctggtg gtcggcgggg gcatcatcgg gctgggcgtc gcctggcgct cggcgcagcg
    14521 cggcctggcg gtcgcgctgg tcgatccgtg gccgggcggg ggcgcggcgc gggtcgccgc
    14581 gggcatgctc gccccggtga ccgaactgca gtacggcgag gagccgttgc tgcgcctggg
    14641 gatggcgtcg aacgagcggt acgccgcgtt cgccgccgag ctgaccgagc tgaccgggct
    14701 ggacaccggc taccgggcca ccggcacgct ggcggtggcg ctggactccg acgaccgcga
    14761 ggagctgcgc gaactgcacg ccttccacgg ccggctgggc ctggcgtccc agtggctgac
    14821 cggccgcgag tgccgccggc tggagccgat gctggccccg ggggtgcgcg gcggcctgca
    14881 cgtcgccggg gaccaccagg tggacggccg ccggctggcc gccgcgctgg tcgtcgcctg
    14941 cgagcgcgcg ggcgtggtgt tccaccgggc ggaggccgcc gagctgctgg tcgaggacgg
    15001 ccgggcggcg ggcgtgcggc tgtcgaccgg cgagcgggtg gcggccgggc gcacggtgct
    15061 ggccgccggg tcgcgcagcc acctgctgcc gggcctgccg gcgggggtgc tgccggcggt
    15121 gcgcccggtc aagggccagg tgctgcggct gcggatgccc accgcgcacg gcccgttcct
    15181 gtcccgcaac gtgcgggcgg tggtgcgcgg gcagcacctg tacctggtgc cgcgggccga
    15241 cggcgagctg gtggtcggcg cgaccaccga ggagctgggc cacgacacca ccgtcaccgc
    15301 gggcggcgtc tacgagctgc tccgggacgc gcacgaactg gtgcccggca tcaccgagtt
    15361 gccgctgctg gagatcggcg cggggctgcg tccgggctcc ccggacaacg cgccgctgct
    15421 cgggccgacc gcgctggacg gcctggccgc cgccaccggg cactaccgca acggggtgct
    15481 gctcaccccg gtcaccgcgg acctgctcgc cgactacctg gccaccggtg aactcccgcc
    15541 gctggccgcc gacttcaccc ctgaccgctt cacccccaag gtccccgcat gaacaccatc
    15601 gccctgaccg tcaacggcga gccgcgcacc ctgcccgccg ccaccacgct ggacgtggtg
    15661 gtcgccgagg tgtcggccgc caacaccggc gtcgccgccg ccgtcaacga ggccgtggtg
    15721 ccccgcagtt cgtggcccgc cacggcgctc ggcgagggcg accgggtcga gatcctcacc
    15781 gccgtccagg gaggctgaac catggctgac gacgcgctgg tcatcgccgg caccaccttc
    15841 tcctcccgcc tgatcatggg caccggcggc gctcccagcc tggaggtgct ggagcaggcg
    15901 ctgaaggtct ccggaaccga gctgaccacg gtggcgatgc gccgggtcga caccgccacc
    15961 cagggctcgg ttctggaggt gctctcccgc aacggcatcc gggtgctgcc caacaccgcg
    16021 ggctgctaca ccgcgggcga ggcggtgctg accgcccggc tggcccggga ggcgctcgaa
    16081 accgactggg tgaagctgga ggtgatcgcc gacgagcgga ccctgctgcc cgacccgatc
    16141 gaactgctgg acgccgccga gacgctggtc gacgacggct tcaccgtgct gccgtacacc
    16201 aacgacgacc cggtgctggc ccgcaagctg gaggacgtcg gctgcgcggc gatcatgccg
    16261 ctgggctcgc cgatcggctc cggcctgggc atccgcaacc cgcacaactt ccagctgatc
    16321 gtggaggccg cgaacgtccc ggtggtgctg gacgcgggcg cgggcaccgc gagcgacgtc
    16381 gcgctggcga tggagctggg ctgctcggcg gtcatgctgg cctccgcggt gacccgcgcg
    16441 caggacccgg tgctgatggc ggaggcgatg cgcaaggcgg tcgaggcggg acggctggcg
    16501 caccgggccg ggcggatccc gcgccgctac tacgccgagg cgtcctcccc caccgcgggc
    16561 ctggccgaca cccgcgagcg tccggcgttc tgagccgcgc ccgccggggc gaaccgacca
    16621 ccgccccggg ggcgtccctg cgggcacggg ccggtcgccg gtccgccccg acatccggcc
    16681 gctcccggtg ggcgaccggt ccgaccccta cactcctctg gtggacatga ccctcgacga
    16741 ccccctgcac ggcgtgctgc tcgacggccg ctaccggatt gagcagcgga tcgcggtcgg
    16801 cggcatggcg accgtctacc ggggcaccga cacccggctg gaccggacgg tggcgctgaa
    16861 gctgatgcac ccctcgctga tcggggacgc cgacttcacg gcccgcttca tccgggaggc
    16921 gaaggcggtg gcccggcttg cccacccgaa cgtggtgaac gtgctggacc agggcgccga
    16981 cccgcgggcc gtgttcatgg cgatggagta cgtgcccggc cgcaacctgc gcgacgtgct
    17041 gcgcgaccgc ggggcgctgt cggtgcgggc cgcgctggac gtgctggagc cggtgctggc
    17101 ggcgctcggc gcggcgcacc gggccggcct ggtgcaccgg gacgtcaagc cggagaacgt
    17161 gctgatcacc gacaacggca tggtgaaggt cgccgacttc ggcctggtcc gggtgctgga
    17221 gggcggcgac gcgacgggcg cctcggccac cgagaccggc cagctgctgg gcaccgtctc
    17281 ctacctggcg ccggagcaga tccgccagga gcccaccgac cagcgggtgg acgtctacgc
    17341 ggcgggcatc ctgctgtacg agatgctgac cggcgccaag ccgcacaccg gggagcacgc
    17401 cgcccaggtg atgtaccggc acctgcacga ggacgtcccg gcgccgtcgc tgaccgcgcc
    17461 cgcggtgggc ccggagctgg acgcgatagt ggcggcggcg acctcccggg acccgcaggc
    17521 ccggccgtgg gacgcggtgg agctgctggc cgcggtgcag cgggcccgcc gctcgctgcc
    17581 cgtcgagcag ttggacgcgg agccgcccgc ctcgacccgg cccaccccgc gctacagccc
    17641 gggcgaggcc accgcggtgc tcgagcagct cccgccgctg gagcgcacca gcgtgctgga
    17701 ggtcccgccg gagctgctgc cgccggtgcg cccggtggtg aacgacgacc cgccgcgcgg
    17761 ccggccgcgc cgctcccccc gctcggcctt cggccgccac ccggcggcct ggtcggcggt
    17821 gctggtcgcg ctgctgctgg tggtgggcgg cgtgacgtac gcgctgtcca gcgcggtgta
    17881 cgcgacggtg cccagcgtgc tggggcagaa ccgggagcag gcggcggcga cgctggaccg
    17941 gcagggcctg cacggctcgt tcagcgagca gttcagcgag tcggtgccga acggctcggt
    18001 gatctccacc gacccggggg tgggcgccaa ggtccgcaag agcgacgggg tgaaggtgct
    18061 gctctcgcgc ggcccggagc gggtggcggt gccggacgtg accggccgtc cgcaggcgga
    18121 cgccgccaag gcgctgggcg acgcccggct gacggcgggc accagccgcg aggagtacag
    18181 cgacaccgtg ccgaagggct cggtgatctc caccgacccg gcggccggca gcagccagtc
    18241 gcccggctcg ccggtggcgc tgaccgtctc caagggcatg cacgtggtgc cggacgtcaa
    18301 ggggatgggc aaggaggacg cctcgaaggc cctgcaggac gccgggttcg tgccggagat
    18361 cgccggtctg atcccgctcg gcaaggtcac cggccagtcc cccgcggcga acaccccggc
    18421 gaagcagggc agcaccgtga cgatcaccat cagcctgttc tgacgcccgg ccccgggggt
    18481 tcagcgcagc gggccgtccc cgggctgctc ctggtaggag tagcgctgct cgcgccaggg
    18541 gtcggcgagg ttgtggtagc cgcgctcctc ccagaagccg cgccggtcgg cccgcatgta
    18601 ctcgacggcg cgcacccact tggggccctt ccaggcgtac aggtggggca ccaccaggcg
    18661 gaccgggaag ccgtgctcca gggtgagggt gcggccgtcg tggtgggtgg cgaggacggt
    18721 ggacgggtcg gcgaagtcgg ccagccgcag gttggcgctg tagccgtact cggcccagac
    18781 catcacgtgg gtgaccgacg ggtcgggcgg gacgaggtcg aggacggtct tggcggcgac
    18841 gccggtccac tcgttgccga gcatcgagaa cttggtgacg cagtgcagat cgccgcggac
    18901 ggtggtcttg ggcagggcgt ggaagccggc gaagtcccac ctggccttct ccgcgtcggc
    18961 ggtggccccg aacacctgga agtcccagct ctgcggcttg aaccggggca ccggcccgta
    19021 gtgcaggacc ggccagccgc gctgcggccg ctgccccggg gggagcctcg ggtcagtcgt
    19081 cggctgctgt tccggttcgc gctgacccat ggtccccatg gtgacagacg gcgggcgccg
    19141 caccacgggc gcccccgttg cgcgcccccg gggaaatccg ccgcggcgga gggggggaac
    19201 acggggcgaa tccgcgcggg cgttcgggcg agataccccc gaacggccca atgctttcga
    19261 cgtcaccgca gctcagagcg gttccgacgg gccggaaagg gcgatctccg gggcggctgt
    19321 aagcgtgaac ttactggaag cgcacccgtt caactgccac gattcggggc atccggacac
    19381 cgaccggaat gcggacagga aggcaggcca tgcagggcga ccccgaggtc atcgagttcc
    19441 tcaacgagca gttgaccgcc gaactcaccg ccatcaacca gtacttcctg cacgcgaaga
    19501 tgcaggagaa cttcggctgg accaagctcg ccaagtacac ccggcacgag tccttcgacg
    19561 agatgaagca cgccgagatc ctgaccgacc ggatcctctt cctggacggc ctgccgaact
    19621 accagcggct gttccacgtc cggatcgggc agaccgtcaa ggagatgttc gaggccgacc
    19681 ggcaggtcga ggtcgaggcg atcgaccggc tgcggcgcgg gatcgtggtg atgcgcgcca
    19741 agaacgacgt cacctcggcg aacatcttcg aggccatcct ggaggacgag gagcaccaca
    19801 tcgactacct ggacacccag ctggaactgc tggacaagct cggcgaggcg ctctacatcg
    19861 cgcagctgat cgagcagccg gagagctgag ccggagaacc gggccggagg gctgggccga
    19921 acgggggggt caggcggcct tcggggcgac ggcgggagcg gtggccgggt cggccaggcc
    19981 gagccgttcg gccagccggg cggtcgggca ggggcgggcg ccgtgctcgc cgagcagcgc
    20041 ctggatgcgc cgcacgcagg aaccgcagtc ggtgccggcc ttgcagccct gggctatctg
    20101 gcgcggggtg ttggccccct cgtcgatctt ctgcttgacc tgggcctcgg tgaccgcgtg
    20161 gcacatgcac acgtacatgt gcggcccctt ccacgattgg tgcggtttac tgagccttac
    20221 cttacctggc gctccgggta cgaaaaaggc ccctccgccc ggaatcaccc ggaagcggag
    20281 gggccttcgt cacatcggga ccctcgggtc accggccgct cactggccgc ggtacatctc
    20341 ggcgaccagg aacgccaggt ccagcgactg gctgcggttg agccgcgggt cgcaggccgt
    20401 ctcgtagcgc tggtgcaggt cgtcgaccag cacctcgtcg ccgccgccga cgcactcggt
    20461 gacgtcgtcg ccggtcagct ccacgtggat gccgcccggg tgggtgccca gcgcgcggtg
    20521 cacctcgaag aagccccgga cctcgtccag cacgtcgtcg aacttgcggg tcttgtggcc
    20581 gctggaggcc tcgaaggtgt tgccgtgcat cgggtcggtg atccacacca cctgggcgcc
    20641 ggacgcggtg accttctcca ccagggtcgg caggtggtcg cggatcttgc ccgcgcccat
    20701 ccgggtgatg aaggtgagcc ggccgggctc gcgctccggg tcgaggcggt cgatcagggt
    20761 cagcgcgtcg tccaccgtgg tggtggggcc gagcttgacg ccgatcgggt tgcggatctt
    20821 cgacgcgaac tcgatgtgcg cgtggtccag ctgccgggtg cgctcgccga tccacaccat
    20881 gtggccggag acgtcgtaca gctcgccggt gcgcgagtcg gtgcgggtca gcgccgtctc
    20941 gtagtccagg atcagcgcct cgtgcgagga gaagaactcg accgtcttga actcctccgg
    21001 ggccaccccg caggcgttca tgaaggccag cgcctggtcg atctcccggg ccagctgctc
    21061 gtagcgctgg ccggccgggg agttgcgcac gaagtcctgg ttccagg
//
