LOCUS       NZ_CP054916            23499 bp    DNA     linear   CON 31-JUL-2024
DEFINITION  Streptomyces sp. NA02950 chromosome, complete genome.
ACCESSION   NZ_CP054916
VERSION     NZ_CP054916.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. NA02950
  ORGANISM  Streptomyces sp. NA02950
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9619720)
  AUTHORS   Zhang,B., Shi,J. and Ge,H.
  TITLE     Genome mining for natural products
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9619720)
  AUTHORS   Zhang,B., Shi,J. and Ge,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUN-2020) Institute of Functional Biomolecules, State
            Key Laboratory of Pharmaceutical Biotechnology, Nanjing University,
            No.163 Xianlin Avenue, Nanjing, Jiangsu 210046, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. v2.05
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013364155.1-RS_2024_07_31
            Annotation Date                   :: 07/31/2024 07:40:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,566
            CDSs (total)                      :: 8,476
            Genes (coding)                    :: 8,147
            CDSs (with protein)               :: 8,147
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 329
            CDSs (without protein)            :: 329
            Pseudo Genes (ambiguous residues) :: 0 of 329
            Pseudo Genes (frameshifted)       :: 152 of 329
            Pseudo Genes (incomplete)         :: 270 of 329
            Pseudo Genes (internal stop)      :: 20 of 329
            Pseudo Genes (multiple problems)  :: 101 of 329
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:05:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9276902
            Orig. end                         :: 9300401
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054916.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23499
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="blactam"
                     /region_number="40"
                     /rules="(BLS or CAS or tabtoxin)"
                     /tool="antismash"
     cand_cluster    1..23499
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(BLS or CAS or tabtoxin)"
                     /kind="single"
                     /product="blactam"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23499
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:13499](+)"
                     /cutoff="20000"
                     /detection_rule="(BLS or CAS or tabtoxin)"
                     /neighbourhood="10000"
                     /product="blactam"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13499
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(BLS or CAS or tabtoxin)"
                     /neighbourhood="10000"
                     /product="blactam"
                     /protocluster_number="1"
     misc_feature    complement(198..211)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.74"
                     /tool="antismash"
     misc_feature    complement(445..465)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.65"
                     /tool="antismash"
     misc_feature    complement(890..903)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    1003..1017
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.77"
                     /tool="antismash"
     gene            1035..4229
                     /locus_tag="HUT19_RS39890"
                     /old_locus_tag="HUT19_39890"
     CDS             1035..4229
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003961118.1"
                     /locus_tag="HUT19_RS39890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39890"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_176187897.1"
                     /transl_table=11
                     /translation="MKDDVRSPGLRFEILGPLSVSSDVTKVDLGAPRQRALLALLLIHV
                     GSVVSLPVIINAIWGSNPPSKVTGTLQAYVSRLRKLLHEHDRSIRLVHHLQGYLLEADA
                     QLVDAAVFEAKARDCRELLKSGDLEVARSTAWSALELWKGTPMGELYGYDFAVAEADRL
                     EHLRLRVLEVWAQACLELHAYGEVTLRLGEELCRNPGLERLGGQLMVAQYHSGQSADAL
                     LTYERMRNAVAEDLGADLSRELQALHGKILRQELEASPVSESAGRTAPAPGSAPVPAPP
                     ESKKPAPSVSPQPGDRLIGRQAEMQRLERLLAGARSGRGHLLLVCGEQGIGKTRLLQHS
                     ERCLAASGFRTVRSQCIGALSAPGYWTWDHVVRQLEVASDASMAVAADLVAHEDWLPEQ
                     HLTHQMRIVQAVLSAAERTPAVLLLEDLHLAPVPALEVLQLLVKQIIRARVMILATLRD
                     HELAKNPAVRRAVGRILQESSSSLLRLEGLAEEESHELIASASGAAPSPNEALRLQRAS
                     GGNPFLLLSMVSAQTTGKRLQRSSVPLELREMLHGRLSECSPGTLDVLTLCAVIGMSVH
                     RPLLADLLSTLELPHTLIDDAVQTGLLRHDRTADGRLSFVHGLTRDFLLDDTQPVTLAR
                     WHQHVATTLALRFQPGDDAAEIRRHCLAAARLLGARMGVRPLLTLADREQARFAHAAAL
                     HWLEGAASVVAALPGDQQTSALKLQLRKRMIRLHALIEGYGSDRVEKILWHAQQLERTF
                     DRTQPTGLLHIQAMSAITAGQYSQAAEIAVLLYELADHGGGRAARSAACYVEGVTLYVS
                     GRPDEALGALTQGVEIIDSLLDASCAPTRLSALLRDQRIDYRAYLALSHCLRGDEIQTQ
                     RYRSQLLHLTRSDRYIRPWDRAFARYVDALIAITEDDVQRAWLAGRAGRDLAVRCRLPF
                     WHRMLAVPLGWAEVHQGMHERGLARMRKALHDSARHRTLLRRTLHLGLLADALHRMGAH
                     DEARRTITSAAEEIEERDEYFCFLPQWPFARLLGESDTGSTAAHQVDHERRLIGMSRVG
                     DGRGGFCSVSSPRRFK"
     misc_feature    1158..1160
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    1536..1538
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    3063..3065
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4598..5164)
                     /locus_tag="HUT19_RS39895"
                     /old_locus_tag="HUT19_39895"
     CDS             complement(4598..5164)
                     /EC_number="1.5.1.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090796.1"
                     /locus_tag="HUT19_RS39895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39895"
                     /product="flavin reductase family protein"
                     /protein_id="WP_176186025.1"
                     /transl_table=11
                     /translation="MSRSVQGSSVQCGQESVAAGRLRWVAGHYPTGVVLVTGPRPAPEQ
                     PPPAMVVGTFTSVSLHPALVGFLPSQSSTTWPRIRAAGRFCVNVLGADQEQVCRSFATI
                     DPHRWEVPHQETATGSPVLLDALVWFDCEVAGEVAAGDHWFVTGAVHDLGVQRPGPPLV
                     FLRGDYGHFAEGSDAARSGQPARPV"
     misc_feature    5387..5402
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.69"
                     /tool="antismash"
     gene            complement(6319..6768)
                     /locus_tag="HUT19_RS39900"
                     /old_locus_tag="HUT19_39900"
     CDS             complement(6319..6768)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003961116.1"
                     /locus_tag="HUT19_RS39900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39900"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_254886072.1"
                     /transl_table=11
                     /translation="MAPAVMTDEQRKAVITAYLKAFDNGGIGRHGSSVLDFFAEDADFF
                     FPKWGLAHGTSEIARMFSGLGSTVTSVTHHFWSFNWITTGTDLLAVEGTTHGEHRDGPW
                     RVGVPEWGAGRWCGVFEVRDFLIQRAFIYLDPDYAGKDVARYPWL"
     gene            complement(6929..7924)
                     /locus_tag="HUT19_RS39905"
                     /old_locus_tag="HUT19_39905"
     CDS             complement(6929..7924)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090799.1"
                     /locus_tag="HUT19_RS39905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39905"
                     /product="aldo/keto reductase"
                     /protein_id="WP_176186029.1"
                     /transl_table=11
                     /translation="MPASMRPPVRALRDLHVSAQGLGCLPTTDFYGRAEPDRSLATIRA
                     ALDAGVTLLDTADVQGLGAGEKLLGQAVAGRRDEVVIATKFGMVRSADGGFQGLCGKPS
                     YVRGACERSLLRLGVDHIDLYYQHWIDPAVPVEETAGAVAELVREGKVRYFGLSEPSAG
                     TLRRADAVHPVTAVQSEWSLWSRDIEAEVAPASRALGIGIVAYAPLGRGFLTGGIHTID
                     DLAAEDFRRSQPRFSAVGLAHNQSLLDRLRPVADGLGLTLAQLALAWLHHRGPDVVPIP
                     GTSDPGHLTENLAAASVQLDQAARAAVAEAIAVPVHGERYAPAMLAMTGN"
     misc_feature    8280..8290
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            8284..9999
                     /locus_tag="HUT19_RS39910"
                     /old_locus_tag="HUT19_39910"
     CDS             8284..9999
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090800.1"
                     /locus_tag="HUT19_RS39910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39910"
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="WP_176186032.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2.5e-42, bitscore:
                     143.3, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-30, bitscore:
                     105.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRVSATPGNHPTTAHALLRRLRDHGVQTVFGVVGREAASILFDE
                     VEGIDFVLTRHEFTAGVVADVLARISGRPQACWATLGPGMTNLSTGVATSILDRSPVIA
                     LAAQSESYDIFPNDTHQCLDSVAVMRPMTKYAAELQRPDDITDLVDSAVAAATTEPVGP
                     SFLSLPVDLLVGEIDTTQDRPTVRAPRKPVGAVQDGWQTAAQQSADLLAAAEHPVLVVG
                     AAAIRSGAVPAIRALAERLNIPVITTYIAKGVLPAGHRLNYGAVTGYMDGILSFPALET
                     LFGPADLILTLGYDYAEDLRPSMWQRGGAKQAVRVSPTVNPIPRVYRPDVDVVTDVLAF
                     VEHLDAHTAEVVPKTPHDIAPLRKRIVEFLSDSERYTDGMRVHQVIDCMNTVMTETAEP
                     GEGTIVSDIGFFRHYGVLFAHADQPFGFLTSAGCSSFGYGIPAAMGAQLARPGQPTFLI
                     AGDGGFHSNSSDLETIARLNLPIVTVVVNNDTNGLIELYQNIGHHRSHDLAVKFTGVDF
                     TDLARANGVEAVRAATRQELLAALRKGAGLGRPFLIEVPVNYDFQAGGFAALSI"
     gene            10001..11524
                     /locus_tag="HUT19_RS39915"
                     /old_locus_tag="HUT19_39915"
     CDS             10001..11524
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     blactam: BLS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152696.1"
                     /locus_tag="HUT19_RS39915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39915"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_176186034.1"
                     /sec_met_domain="GATase_7 (E-value: 4.6e-13, bitscore:
                     48.1, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="BLS (E-value: 5.6e-156, bitscore: 518.4,
                     seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 4.6e-25, bitscore:
                     87.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARTLPSATGFLAAVQQDGGQVPQPAFASLGSRTEEREERHGHTL
                     HTRLLHAGAPEAARACGPGAAVVFAGELYNQAELRSLLPRGTDPAGDAQLVLALFDTYD
                     LHAFRLLNGRFAALVHGEGRIVLATDHVGSVPLYLTAALGRVLAATEAKALRTAPMGLP
                     LPAARPIRRLPGVHQVPAGTVLEVVLGTGTCTAHRTWAPPHSRRITAEDEAVAAVRRAL
                     EHAVRVRLGPEAPLVVLSGGIDSASVAALADRAAGPIDTISMGTDDADEFSQARIVTEH
                     LGTTHRELIIPTADLLRRLPHTVWAAESLDPDIIEYLLPLTALYLRLDGTGRRILTGYG
                     ADIPLGGMHREDRLPALDTALAHDMETFDGLNEMSPVLSGIGGHWSTHPYWDRDVLDLL
                     VSLEAGMKHRYGQDKWVLRAAMGDVLPQETVLRPKLGVHEGSGTTSSFSRLLTDAGVPD
                     GRVHHAKRLVVQELFDQVVVAGRHPDEVATDDAVQLVVDRLERHAQPIP"
     gene            11566..12510
                     /gene="speB"
                     /locus_tag="HUT19_RS39920"
                     /old_locus_tag="HUT19_39920"
     CDS             11566..12510
                     /EC_number="3.5.3.11"
                     /GO_function="GO:0008783 - agmatinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="speB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090802.1"
                     /locus_tag="HUT19_RS39920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39920"
                     /product="agmatinase"
                     /protein_id="WP_176186037.1"
                     /transl_table=11
                     /translation="MERIDITVSPRYAQIPTFMRLPHDPAPRGRDVVVIGAPYDGGTSY
                     RPGARFGPRAIRNESGLIHGVGIDRGPGTFALISCVDAGDIDLTPFNMHIAMDTAQRRL
                     GELLVDNAAFLMLGGDHSLTLAALRAVSAKHGRLAVLHLDAHSDTNPAFYGGEYHHGTP
                     FRHAIEEKLIDPQRMVQIGIRGHNPEPDALDYARGHGVRIITADDFADLGKDATTRLVR
                     DIVGDTPLYVSVDIDVVDPAFAPGTGTPAPGGPASREVLALLRGVGDLQPVGFDVMEVS
                     PLYDHGGITSVLATEIGAELLYQYARAHNQEHT"
     gene            12525..13499
                     /gene="cs1"
                     /locus_tag="HUT19_RS39925"
                     /old_locus_tag="HUT19_39925"
     CDS             12525..13499
                     /EC_number="1.14.11.21"
                     /GO_function="GO:0033758 - clavaminate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0033050 - clavulanic acid biosynthetic
                     process [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (110-299). E-value: 2.6e-19. Score:
                     62.0. Matches aSDomain:
                     nrpspksdomains_HUT19_RS39925_TauD.1"
                     /codon_start=1
                     /gene="cs1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     blactam: CAS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046: Dioxygenase TauD/TfdA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003961114.1"
                     /locus_tag="HUT19_RS39925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39925"
                     /product="clavaminate synthase Cs1"
                     /protein_id="WP_176186039.1"
                     /sec_met_domain="CAS (E-value: 5.8e-185, bitscore: 613.0,
                     seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="TauD (E-value: 3.5e-17, bitscore: 62.0,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVVDCTARAGELRALTARLPQPPRADLYAFLDSAQNAAAALPDA
                     LATAVDTFNAEGCRDGYLLLRGLPVEDDSALPPTPTSTPAPVDRPLLTMEAMLGIVGRR
                     LGLHTGYQELRSATVYHDVYPSPNAHHLSSETSETLLEFHTEMAYHLRQPNYVMLACSR
                     ADHENKAATLVASVRKALPLLSTEVRERLHERKMPCCVDVAFRGGVADPGAIAQVKPLY
                     GDPKDPYLGYDRELLSPCDPKDVAAVAMLSKALDEVTEAVYLTPGDVLIVDNFRTTHAR
                     TPFTPRWDGRDRWLHRVYIRTDRNGQLSGGERAGDVVAFTPRG"
     aSDomain        12855..13421
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUT19_RS39925_TauD.1"
                     /evalue="2.60E-19"
                     /label="HUT19_RS39925_TauD.1"
                     /locus_tag="HUT19_RS39925"
                     /protein_end="299"
                     /protein_start="110"
                     /score="62.0"
                     /tool="antismash"
                     /translation="YQELRSATVYHDVYPSPNAHHLSSETSETLLEFHTEMAYHLRQPN
                     YVMLACSRADHENKAATLVASVRKALPLLSTEVRERLHERKMPCCVDVAFRGGVADPGA
                     IAQVKPLYGDPKDPYLGYDRELLSPCDPKDVAAVAMLSKALDEVTEAVYLTPGDVLIVD
                     NFRTTHARTPFTPRWDGRDRWLHRVY"
     gene            13653..14834
                     /gene="argJ"
                     /locus_tag="HUT19_RS39930"
                     /old_locus_tag="HUT19_39930"
     CDS             13653..14834
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /GO_function="GO:0004358 - glutamate N-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argJ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1220: bifunctional ornithine"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003952513.1"
                     /locus_tag="HUT19_RS39930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39930"
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="WP_176186041.1"
                     /transl_table=11
                     /translation="MTDSETYEPRGFSVHTAPVGLRDDGRDDFTVLLSTAPATVSAVFT
                     RSRFAGPSVRLSRAAAADHRARGVVVLARNANVATGAEGERNAREVRALVARASGLSDE
                     ELLIASTGVIGHQYPMPALRDHLKTLAVPFPEGGFDRAARAIMTTDTRPKHAFRRIGNA
                     TLVGIAKGVGMMEPDMATLLTFFATDARLDPAEQDRVFRRVMDRTFNAVSIDTDTSTSD
                     SAALFANGLAGEVDPVAFEEALYEVALTLVKGIARDGEGAGKLIEVRVHGARDDAQAKR
                     VGKAVVNSPLVKTAVHGGDPNWGRVAMAIGKCSGDTDIEQEKVVIRFGEVAVYPPARQG
                     ARSEEGVRAAVATELAGSEVVIGIDLGIADGAFTVYGCDLTEGYVRLNADYST"
     gene            complement(14822..15829)
                     /locus_tag="HUT19_RS39935"
                     /old_locus_tag="HUT19_39935"
     CDS             complement(14822..15829)
                     /NRPS_PKS="Domain: Abhydrolase_1 (39-157). E-value:
                     1.3e-11. Score: 36.6. Matches aSDomain:
                     nrpspksdomains_HUT19_RS39935_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090805.1"
                     /locus_tag="HUT19_RS39935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39935"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_176186044.1"
                     /sec_met_domain="PF00561 (E-value: 9.7e-11, bitscore: 40.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHRVFDLDALPLLSGELLTDARIGYAVHGTLDADGANAVLCPSF
                     FGGDHTGYDWLIGKGRPLDTSRYCVITVGLFGNGVSSSPSNHPSGADFPLITPQDNVAA
                     QHRLLTEQLGVRELALVTGWSMGAAHTYQWAVSHPRIVRRIAPICGSPVTSEHNQVFLA
                     GLAAALASDGGAERGRRAAGRVFAGWGASHPFWAQRAYQELGFATREEYLTNFWEEFFV
                     AGPATADLLAMVRTWESADVGATPGFGGSADAALASVTAEAVLLPGALDQCFAVADEER
                     VAGVLPRAALKVVPGVWGHLAGAGADAADREFVGGELRRLLARWPATVRADQVE"
     aSDomain        complement(15359..15712)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUT19_RS39935_Abhydrolase_1.1"
                     /evalue="1.30E-11"
                     /label="HUT19_RS39935_Abhydrolase_1.1"
                     /locus_tag="HUT19_RS39935"
                     /protein_end="157"
                     /protein_start="39"
                     /score="36.6"
                     /tool="antismash"
                     /translation="VLCPSFFGGDHTGYDWLIGKGRPLDTSRYCVITVGLFGNGVSSSP
                     SNHPSGADFPLITPQDNVAAQHRLLTEQLGVRELALVTGWSMGAAHTYQWAVSHPRIVR
                     RIAPICGSPVTSEH"
     gene            complement(15962..17146)
                     /locus_tag="HUT19_RS39940"
                     /old_locus_tag="HUT19_39940"
     CDS             complement(15962..17146)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003961112.1"
                     /locus_tag="HUT19_RS39940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39940"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_176186046.1"
                     /transl_table=11
                     /translation="MKSILFYLPTVGSHAQILRGMSGVNPQNYQNMLRQLTRQAQAADE
                     LGYWGLSFTEHHFHVEGFEVSNNPIMLGLYLAMQTQHIRVGQMANVLPFHNPLRLAEDL
                     AMLDHMTRGRAFVGIARGFQKRWAEVMGQTYGVGGTLSDAGENDRRNRALFEEHWEIVK
                     KAWTTETFSHSGARWTIPVKDLEFPYEAVRRYGRGLDDNGTVQEVGIAPKPYQRPHPPV
                     FQPFSFSEDTFRFCAREGVVPIVMNTDDRVVRRLMDLYQEEAEAAGHGTLRRGERVGVM
                     KDVLVSRDADEAHHWAARGGGFIFENWFGPMGFTEALRNVGESGPIGSDYGTLVDRGLE
                     WVGTPDDINRKIEKLVEQHDPEYLLQCQYSGLIPHDVQMRSLELWSTEIAPNWL"
     gene            17136..18088
                     /locus_tag="HUT19_RS39945"
                     /old_locus_tag="HUT19_39945"
                     /pseudo=""
     CDS             17136..18088
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009079782.1"
                     /locus_tag="HUT19_RS39945"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39945"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDFTVVLPFEIWAGVDIGKERHHCVVIKADGERLARIRRDIGLLR
                     RGDEIAVDLRPRRPDVAFDRTVRSTVCVLSCWGSSPRWSGRWIWSTRVR"
     gene            18326..19690
                     /locus_tag="HUT19_RS39950"
                     /old_locus_tag="HUT19_39950"
     CDS             18326..19690
                     /NRPS_PKS="Domain: Aminotran_3 (40-385). E-value: 2.6e-88.
                     Score: 288.2. Matches aSDomain:
                     nrpspksdomains_HUT19_RS39950_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003961111.1"
                     /locus_tag="HUT19_RS39950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39950"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_176186048.1"
                     /sec_met_domain="Aminotran_3 (E-value: 5.6e-84, bitscore:
                     281.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSAPSTPPGAPGTELAAADRATLIHPTLAAHRTDRTVLVSGSGS
                     RVRDARGREYLDASAALSVIQVGHGRQELAQAAAEQMTRLGYFHTWGTVSNDRAVELAA
                     RLVRLSPEPLCRVYFTSGGAEGNEIALRMARLYHHRRGEPQRTWILSRQTAYHGIGYGS
                     GGVSGFPVYHEGFGPSLPDVHFLTPPHPYRRELFAGADVTDFCLAELRETIERIGPERI
                     AAMIGEPAMAVAGAVVPPADYWPRVADLLRSYGVLLISDEVITAYGRTGHWFAAEHFGV
                     VPDIMVTAKGITSGYVPHGAVLTTEEVAAEVTGDHGFPIGYTYTGHPTACAVALANLDI
                     IDREGLVANATAIGDYLGSRLAELAGLPVVGEVRQLGLMLAVELVTDQQSRRLLTGGTV
                     ALADALQEQAGILLRTTPYALLINPPLVFTREDADELVDGLRSVLSRTGPDGQVH"
     aSDomain        18446..19480
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUT19_RS39950_Aminotran_3.1"
                     /evalue="2.60E-88"
                     /label="HUT19_RS39950_Aminotran_3.1"
                     /locus_tag="HUT19_RS39950"
                     /protein_end="385"
                     /protein_start="40"
                     /score="288.2"
                     /tool="antismash"
                     /translation="SGSGSRVRDARGREYLDASAALSVIQVGHGRQELAQAAAEQMTRL
                     GYFHTWGTVSNDRAVELAARLVRLSPEPLCRVYFTSGGAEGNEIALRMARLYHHRRGEP
                     QRTWILSRQTAYHGIGYGSGGVSGFPVYHEGFGPSLPDVHFLTPPHPYRRELFAGADVT
                     DFCLAELRETIERIGPERIAAMIGEPAMAVAGAVVPPADYWPRVADLLRSYGVLLISDE
                     VITAYGRTGHWFAAEHFGVVPDIMVTAKGITSGYVPHGAVLTTEEVAAEVTGDHGFPIG
                     YTYTGHPTACAVALANLDIIDREGLVANATAIGDYLGSRLAELAGLPVVGEVRQLGLML
                     AVELV"
     gene            complement(20933..21532)
                     /locus_tag="HUT19_RS39955"
                     /old_locus_tag="HUT19_39955"
     CDS             complement(20933..21532)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998962.1"
                     /locus_tag="HUT19_RS39955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39955"
                     /product="hypothetical protein"
                     /protein_id="WP_176186050.1"
                     /transl_table=11
                     /translation="MHEGKPANGKRRRTRVPLWRWRNNPIRRRDDILEAWLLLAVWGLI
                     AVGGTAAGVVTAHAADRVFAQQRADRTPVRAVLLDDVPRPAMSGLDRDLSSARVRWTNS
                     DGSTRNGMTVVATGKEAGSTVRIWIDAQGKLSTQPPTPAKAAAEAGLLGASAALALSGL
                     VIGIGSAGRWWLDRRRIHQWDTEWTVVGPQWSHKTT"
     gene            21773..21943
                     /locus_tag="HUT19_RS39960"
                     /old_locus_tag="HUT19_39960"
     CDS             21773..21943
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUT19_RS39960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUT19_39960"
                     /product="hypothetical protein"
                     /protein_id="WP_176186053.1"
                     /transl_table=11
                     /translation="MRDFTAQRHSQWLPAQPFDSYPVLAPLTTEHDRPSDRLRAGQALE
                     HLLLVATAHGL"
     gene            complement(22205..22594)
                     /locus_tag="HUT19_RS39965"
                     /old_locus_tag="HUT19_39965"
     CDS             complement(22205..22594)
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072605.1"
                     /locus_tag="HUT19_RS39965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39965"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_176186055.1"
                     /transl_table=11
                     /translation="MVKTLITSAPRRTDRAVGRTTVVELRGEIDILTAPPLEARLDELT
                     AAVLSDLVVDLRAVSFIDCTGLRVLCRARNRLMERHGRLRLVTDSSQFLRILSGAGLDG
                     VFEICERLPEAVSAVPAGAFTAAAG"
     misc_feature    complement(22630..22644)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.9"
                     /tool="antismash"
     misc_feature    22631..22645
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.68"
                     /tool="antismash"
     gene            22771..23211
                     /locus_tag="HUT19_RS39970"
                     /old_locus_tag="HUT19_39970"
     CDS             22771..23211
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670099.1"
                     /locus_tag="HUT19_RS39970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_39970"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_176186057.1"
                     /transl_table=11
                     /translation="MYPNDGMRELGCHECLRLLATAPIGRIVHTRQALPAVVPVNFGLD
                     NDGAVLLRTSAGSELARAVDGAVVDFEADAVDADTHSGWSVVVTDRAEIVTDPAEAARL
                     ERIGPRSWAPLPEEVFVRIEPELVTGRELVGGRTMYGLDLSA"
ORIGIN
        1 cggcatgtga tggacctggg cggcggatgt ggcaccctgt tggccgcact cctggacagc
       61 gctcctttcc tgcggggcac cttgctggaa ctgcccgaga cggcggtcgg cgcgttcggt
      121 gaactttcgg ccaccagcgc ggcgaaccgg atctccgtgg tcggcggcag cttcttcgat
      181 ccccttccga cgggcgccga actcatgctc ttcggcggct aggaaggttg tctgacggag
      241 tacgaccaac tggccgcagc agcggggctg gccatcacct ccgtctcacc tgcgtcgtcc
      301 ggtgtctttc atcatggagt gtcgagaggc ggccgggaac cgccacacca attgaccggc
      361 gacggacgaa gccactgtgg gctcgctcgt atcacgtacg gaggtctgtg tctcccgtcg
      421 ccagttcacc tcgaaatgcg tgaccagaag tcaccccgac aagatcgctg accagatcct
      481 tctccgcggt gctgcggtgg atcgacaccg atccagagcc gttcgacctc agcacctacc
      541 tcgacctgct gctcgagctc gtcctgcgag tctggcctct ccctgcaagg gccgatgacc
      601 gtcgaccggg gccacgctcc aggccacggc gggggagacc ggcccggatg gcagccaacc
      661 tcaaaccccg aaaccgagag aggttgccga ccggagcgct gtccggcggc acttcggtag
      721 gccgcagcgt gcgaggcgga ccgccggggc atccggatcc cctctcgtcc gccatgcctc
      781 cgtcgtgcga ttccctaatc ttctggcgac tgccgggctg gctgacactg cttgggaggc
      841 tcctctgccg cgcacaaggc cgagatcctc gccctgcgcc acggatgtgg tgatcgggag
      901 caagtgggtt acacctcttg gcgcattctc ctcttgctcc tgctcggagt cccggtctcg
      961 gaaatcactg agggttttcc gacagcagcc tctgtatcta ccgatcttca tacaatctcc
     1021 agttgggata cgcgatgaaa gatgatgtac gttcccctgg gcttcgattc gaaatccttg
     1081 gccccttgag tgtgagttcc gatgtaacga aggtggacct cggtgcgccg aggcagcgcg
     1141 ctctgctcgc cctgctgtta atccacgtgg gcagcgtggt atctctgccc gtgatcatca
     1201 acgcgatctg gggatccaac ccaccgagca aggtcacggg gacgctgcag gcttacgttt
     1261 cccggctgag gaagctgctc cacgagcatg atcgctccat ccgactcgtc caccatctcc
     1321 agggatatct gctcgaagcc gatgcgcagc tggtcgacgc cgcggtcttc gaggccaagg
     1381 ccagggactg ccgggaattg cttaagtccg gagatctcga agtcgctcgc tcgacagctt
     1441 ggtccgcgct ggagctgtgg aagggcactc ccatgggcga gttgtacggt tatgacttcg
     1501 cggtggcgga agcggaccgc ctggaacatc tccgattacg ggtactggaa gtgtgggccc
     1561 aggcgtgtct cgaactgcac gcctatgggg aagtgactct ccggctcggc gaggagcttt
     1621 gccgcaaccc cggattggag cggttgggtg gccagttgat ggtggctcag taccactccg
     1681 gtcagtcggc ggacgctctc ttgacgtatg aacggatgcg caatgcagtg gcggaggacc
     1741 tgggggccga tctcagccgg gaattgcaag ctctgcacgg gaagattttg cgtcaggaac
     1801 tagaggcatc accggtctcg gagtcggcag gccggaccgc gcccgcgccg ggatccgccc
     1861 cggtacctgc gccgccggaa tcgaagaaac cggcgccgtc cgtgtcccca cagccgggtg
     1921 accggctcat cggccgtcaa gcggagatgc agcggctgga gagactgttg gcgggcgccc
     1981 gaagcggtcg tggccatcta ctgctggtct gcggcgagca gggaatcgga aagacgcggc
     2041 tgttgcagca ctcggagcgt tgtcttgccg ccagcgggtt ccggacggtg cgctcacagt
     2101 gcatcggggc cctgtcggct ccgggctact ggacctggga ccacgtcgtg agacagctgg
     2161 aggtggcgag cgacgcgagc atggctgtcg ccgcggacct cgtcgcccat gaggactggc
     2221 tgcccgagca gcacctcacc caccagatgc ggatcgtcca ggccgtgctc tccgccgcgg
     2281 agcggacacc ggcagtgctt ctgctagagg acctacatct cgcccccgtg cccgcactgg
     2341 aagtgctcca actgctggtc aagcagatca tccgtgcccg ggtcatgata ttggccaccc
     2401 tgcgcgacca cgaactggcg aagaacccag cggtacgacg cgccgtgggc cgtatccttc
     2461 aggaaagcag tagcagcctc ctccgactgg aggggctcgc cgaagaagag agtcacgagt
     2521 tgatcgcctc ggcctcggga gcggcgccct cgcccaacga agccctgcgg ctccagcgcg
     2581 cctccggcgg caacccattc ctccttctca gcatggtctc cgcgcagaca accggaaagc
     2641 ggctgcagag gtcatctgtc cccctcgaac tacgcgagat gctgcatggg cgactgagcg
     2701 aatgctcccc gggcacgctc gacgtgctca ccctctgcgc cgtgataggc atgagcgtgc
     2761 accgtcccct gctcgcggac ctcctgtcca ctcttgaact gccgcacaca ctgatcgacg
     2821 acgcggtaca gaccggcctg ctgcgccacg accggaccgc cgacggccgg ctctccttcg
     2881 tgcatgggct gacgcgtgac ttcctgctcg acgatacgca gccggtcacc ctcgcccggt
     2941 ggcaccagca cgttgccacc accctggccc tgcggttcca gccgggtgac gatgccgctg
     3001 agatccgccg ccactgcctg gcagccgccc ggctcctggg tgcccgcatg ggcgtgcgtc
     3061 ctttactgac tctggccgac cgggagcagg cccgcttcgc ccatgcggcc gcactgcact
     3121 ggctggaagg cgcggcgtcg gtcgttgcgg cgctgcccgg ggaccagcag acctctgccc
     3181 tgaaactgca gctgcgcaag cggatgatac ggctgcatgc cctgatcgag ggctacggct
     3241 cggaccgggt cgagaagatc ctctggcacg ctcaacagct ggagcgcacc tttgatcgca
     3301 cacagcccac cggactgctg cacatccagg cgatgagcgc gatcactgcg ggtcagtact
     3361 cgcaggcagc ggaaatcgcc gtcctgctct acgagttggc cgaccacggc ggcggccggg
     3421 cggcccgatc ggcggcctgt tacgtggagg gggtcaccct gtatgtgagc ggccgtccgg
     3481 acgaggcgct cggcgcgctg acacagggtg tcgaaatcat cgactccctc ttggacgcgt
     3541 cctgcgcgcc aacgcggctg agcgcgctgc tgagggacca gcgcattgac taccgggcct
     3601 acctggcgct cagccactgt ctccgcggcg atgagatcca gacccagcgc taccggtcgc
     3661 aactccttca cctcacccgg tccgaccgct atatccggcc ctgggaccgg gctttcgccc
     3721 ggtatgtgga tgccctcatc gccatcaccg aggacgacgt acagcgtgcc tggctggcag
     3781 gcagggcggg ccgggacctc gccgtccgct gccggctccc tttctggcac cgcatgctcg
     3841 ccgtcccgct cgggtgggcc gaggtgcatc aggggatgca cgagaggggg ctggcccgga
     3901 tgcggaaggc gctgcacgac tcggcccggc accggaccct gctgcgccgc acccttcacc
     3961 tcgggttgct cgccgacgct ctgcaccgta tgggtgccca cgacgaggca cggcgtacga
     4021 tcacctccgc cgctgaggaa atcgaggagc gggacgaata cttctgtttc cttccccagt
     4081 ggccgttcgc ccgactgctc ggtgagtccg acaccggcag cacggcagcg caccaagtcg
     4141 atcacgaacg tcgtttgata ggtatgagta gggtcgggga cgggcgcggt ggcttctgct
     4201 ccgtttccag cccccgccgc ttcaagtgaa gtgggccgcc gacgaggtgc cggtggcgcg
     4261 ggagccaggg gccgcgggcc tgcaggcggg ggtgcatccg gtcccgggcg aggacgtcgg
     4321 cccagccgta gcggatggtg tcgcaggtag tggcggcgtc gggcgtatgc cccgtttcag
     4381 gcttggcgaa ggtgaggaca ccgccatgct tgcggggctg cccgccgcgc ggggtggagc
     4441 ggcgccgtcc ggcgtcgcgg agcatgaccc cggtccgagc gcaagccggc cgaccagccc
     4501 aacgggcagg ccgatgccgc tccgctgtcc ggcaggcccg cggaccgctg gtggaagcaa
     4561 ggtgtgcatc ggcaaaccac tggaccggcg gcagaggtca gaccggccgg gcgggttgtc
     4621 cggaccgggc agcgtcgctc ccctcagcga agtgcccgta gtcaccgcgc agaaacacca
     4681 ggggtggacc gggccgctgg accccgaggt cgtggaccgc gccggtgacg aaccagtggt
     4741 cgcccgccgc cacctcgccc gccacttcgc agtcgaacca gacgagcgcg tcgagcagga
     4801 cgggggagcc agtggcggtc tcctgatggg gcacctccca gcggtgggga tctatggtgg
     4861 cgaagctgcg gcagacctgc tcctggtccg ctcccagcac attgacgcag aaacggccgg
     4921 ccgcccggat tcgcggccag gtggtcgagg actgcgaggg aaggaagccc accagcgcag
     4981 ggtgcagcga caccgaggtg aaggtgccca ccaccatcgc gggtgggggc tgctccggtg
     5041 ccggacgcgg cccggtgacg aggaccaccc cggtggggta atggccggcc acccagcgca
     5101 accgcccggc agccacggac tcctggccgc actgcacgga actgccctgc acggaacggg
     5161 acatacggtc tcctttgctc cggtaaggag aggtgccgta ggacttggcc gcggcacctt
     5221 cccgacccgc tgagccgacg gccaacgggc gggctgctcg gcgtaagcca cgcccgagga
     5281 aggcccggac cagctcggcg acgtccgtgg cgaccttgcc ggagccgcgt cgcgccgcag
     5341 tggtcgggcc agcaactcgg ccacctgcgc catgtcgttc tccttcatgc ccagctggtc
     5401 agtccctggg tgccgaggct gcaggcccgg ccacgtcgaa accgcgcccg gccggttcgc
     5461 cggccaggcg gcgggcgtgg cgatgacctg gtgcgcgtaa tcaacctggt gcggcagcaa
     5521 ctcctccagc gtgatcgcca ggctgccgac cgtcgcggag tgggagctcg acgccgggaa
     5581 gggaatccgt gccgccatct tctccgcgcg ggaattcctc ttggtgacca ggagtccgtt
     5641 ctgcgtgccg ggcagcgtct tatgcgtact gtcggagacg ccgtcgagga ccagggtctg
     5701 ggggctgcgg ggcttgcgga cagcagaccg agcaggtgcg aggcgtccag acagatgagc
     5761 gcgtcgggca cggcggcccg tagcgcccgg gagtcgggga agcgcagcgc cgtggaggcg
     5821 tccaggtaaa ccacgtcgac cgagtgctcc gcgatccgcg ccgcgagtgc cgtacgccgg
     5881 atctccaagc gttgccgagt ggaaggggcg gaagtccacc tgtagccgaa gccctggcag
     5941 gtggtgacgg cagcgtagtg gccgccgtcg gcgggggctg gcaccatcac ccggccgccg
     6001 ggtgggcccg ccgcagtgag cacggtgtgc atggagtgca gcccggacag gaaccgcacg
     6061 aaggcgtgcc gggccccgta gaactccttg atgaggtcca cgcagtggcc gtagacgtcc
     6121 ttgagccacg tgacgtcgcc gtagaccgcc accggcgtct ccgagtacgg atagtggttg
     6181 accgcgtcgg tggcgaggtc cgtggcgaga gtcggttctc aaccggaaga ggttgaggct
     6241 gggcctgcgc tgcgaggcgg tcggcacgtt catcagtgct ccttggctgg ggaaaacgga
     6301 ggggaaccgg ggagcgcgtc acaaccacgg gtagcgggca acgtccttgc ccgcgtagtc
     6361 ggggtccagg tagatgaacg cccgctggat gaggaagtcc cgtacctcga agacgccgca
     6421 ccagcgcccg gcgccccact cgggcacacc cacccgccag ggaccgtcgc ggtgctcgcc
     6481 gtgcgtggtt ccctcgacgg cgagcagatc ggtcccggtg gtgatccagt tgaaggacca
     6541 gaagtggtgc gtgaccgatg tgactgtgct cccgagaccg ctgaacatcc gggcgatctc
     6601 ggacgtgccg tgggccagtc cccatttcgg gaagaagaag tcggcgtcct cggcgaagaa
     6661 gtcgagcacg gaactcccat gcctgccgat cccaccgttg tcgaaagcct tgagatatgc
     6721 ggtgatgacg gccttgcgct gctcgtccgt catgacagcg ggtgccatgg gcatgaacga
     6781 cctccggatg tgccgggaat ctgcgggagg gggcgccgca ctcacgggac ggcgtcgtcg
     6841 ttgcggccgc ccggcggaca tgctccaccg tcgcagggcg gtcttgccgc gggcttgacg
     6901 tcccgctgcg gcccggcctt gcaagcagtc agttgccggt catggcgagc atcgcgggcg
     6961 cataacgctc cccgtggacc gggacggcga tcgcctccgc caccgccgcc cgggcggcct
     7021 ggtccagctg caccgaggcc gcggcaaggt tctcggtcag gtggcccggg tcgctggtgc
     7081 ccgggatggg gacgacgtcc gggccgcggt ggtggagcca agccagggcg agctgggcca
     7141 gcgtcaggcc gaggccgtcg gcgaccgggc gcagccggtc cagcagcgac tgattgtgtg
     7201 ccaggccgac ggcgctgaac ctcggctgac tgcggcggaa gtcctcggca gccaggtcgt
     7261 cgatggtgtg gatgcctccg gtcaggaagc cgcggcccag cggggcgtac gccacgatgc
     7321 cgatgcccag cgcgcggctg gcaggcgcca cctcggcctc gatgtcccgc gaccacaggc
     7381 tccactcgct ctgcaccgcg gtgaccgggt gcaccgcgtc agcccggcgc agcgtgcccg
     7441 cggagggctc ggacagcccg aagtaccgga ccttgccctc gcgcaccagc tccgccaccg
     7501 cgcccgcagt ctcctccacc gggaccgccg ggtcgatcca gtgttggtag tacaggtcga
     7561 tgtggtccac gccaaggcgg agcagtgagc gttcacaggc cccgcgcaca taggacggct
     7621 tgccgcacag cccctggaac ccgccgtcgg cggagcgcac catgccgaac ttggtggcga
     7681 tcacgacctc gtcgcggcgt cccgctacgg cctggccgag cagtttctcg cccgcgccca
     7741 ggccctggac atcggcggtg tccagcaagg tgaccccggc gtccagtgcg gcgcggatcg
     7801 tggcgagcga ccggtccggc tccgcacggc cgtagaagtc cgtggtcggc aggcagccca
     7861 gcccttgggc actgacgtgc agatcgcgca gtgcgcggac cgggggacgc atggacgcgg
     7921 gcatggcgga acctccactg cagatgccgc tggggcaagg ggaaaggaag ggccgaccgc
     7981 agaaacggcc gcgtcgaaag ggcggaaagg gctgcggaat ccggcggcag cacggtagcc
     8041 gccggcaccc cgtggccaca atgccgtccc ttttcaagcg tttgatgaag cgccggcgtg
     8101 ccgcggcggc gccggagccg gccgcggcgg attcccgcaa gggaaacgtc cacaaccgtg
     8161 caagcccctg tccgcacagt gagcacggcg cctttaccgg cccgttccgt cgggcgccgg
     8221 cccgtggcgg cacatccgcc ccgagccgat acggccccct atccgtacgc atgaggagac
     8281 gccatgtcac gtgtgtccgc cacccccggc aaccacccga cgaccgcgca cgccctgctt
     8341 cggcggctgc gggaccacgg ggtgcagacc gtgttcgggg tggtcggccg ggaggccgcg
     8401 tccatcctct tcgacgaggt ggaggggatc gacttcgtgc tgacccgcca cgagttcacc
     8461 gccggggtcg tcgccgacgt gctggccagg atcagcggcc ggccgcaggc gtgctgggcc
     8521 acgctgggcc ccggcatgac gaacctgtcc accggtgtcg ccacctcgat cctggaccgc
     8581 tcgccggtca tcgcgctcgc cgcccagtcc gagtcgtacg acatcttccc caacgacacc
     8641 caccagtgcc tggactcggt cgccgtgatg cgtccgatga ccaagtacgc ggcggagttg
     8701 cagcgccccg acgacatcac cgacctcgtg gactccgcgg tcgcggccgc aacgaccgag
     8761 ccggtcggcc ccagcttcct ctcgctcccg gtcgatctgc tcgtcggaga gatcgacacc
     8821 acccaggacc gcccgaccgt gcgcgccccc agaaagccgg tcggcgcggt ccaggacggc
     8881 tggcagaccg cggcgcagca gtccgccgat ctgctcgcgg cggccgagca cccggtgctg
     8941 gtggtcggcg ccgcggccat ccggtccggt gcggtaccgg ccatccgcgc gctggccgag
     9001 cgcctgaaca tcccggtgat caccacctat atcgccaagg gggtgctgcc ggccggccac
     9061 cggctcaact acggtgcggt caccggctac atggacggca tcctctcctt ccccgcgctg
     9121 gagaccctct tcggccccgc ggacctgatt ctcaccctcg gctacgacta tgccgaggat
     9181 ctgcgaccgt cgatgtggca gcgcggcggt gcgaagcagg ccgtccgggt ctcgccgacg
     9241 gtcaacccca ttccgcgggt ctaccggccc gacgtggacg tggtcaccga cgtgctcgcc
     9301 tttgtggagc acctggacgc ccacacggcc gaggtggtgc cgaagacccc gcacgacatc
     9361 gcaccgctgc gcaagcggat cgtcgagttc ctttccgact ccgagcgcta caccgacggg
     9421 atgcgggtcc accaggtgat cgactgcatg aacacggtga tgaccgagac cgccgagccg
     9481 ggcgagggca ccatcgtctc cgacatcggc ttcttccggc actacggggt gctcttcgcc
     9541 cacgccgacc agccgttcgg cttcctcacc tcggccggct gctccagctt cggctacggc
     9601 atccccgccg cgatgggcgc ccagctggcc cgccccgggc agcccacctt cctcatcgca
     9661 ggcgacggcg gcttccactc gaacagctcg gacctggaga ccatcgcccg gctcaacctg
     9721 cccatcgtta cggtggtggt caacaacgac accaacgggc tgatcgagct gtaccagaac
     9781 atcggccacc accgctccca tgacctggcg gtgaagttca ccggcgtcga cttcaccgac
     9841 ctcgcccgag ccaacggggt ggaggcggtg cgggcggcca cccgccaaga actgctcgcc
     9901 gcgctgcgca agggtgccgg tctcgggcga ccgttcctca tcgaggtccc ggtgaactac
     9961 gacttccagg ccggcggctt cgcggccctg agcatctgac atggcccgga cgctgccttc
    10021 cgccaccggc ttcctggccg cagtccagca ggacggtggc caggtcccgc agccggcctt
    10081 cgcttcgctc ggctcccgca ccgaggaacg cgaggaacgg cacggccaca cgctgcacac
    10141 caggttgctg catgccgggg cgccggaagc cgcccgggca tgcggaccgg gggcagcggt
    10201 ggtgttcgcc ggagagcttt acaaccaggc cgaactgcgg tcgctgctgc cgcgcggcac
    10261 cgaccccgcc ggtgacgccc agctcgtcct cgcgctcttc gacacctatg acctgcacgc
    10321 gttccggctg ctcaacgggc gcttcgcagc gctggtgcac ggcgaggggc ggatcgtact
    10381 cgccaccgac cacgtgggct cggtgccgct gtacctgacg gccgcgctgg gccgggtgct
    10441 ggccgccacc gaggccaagg ccctgcgcac cgcccccatg gggctgccgc tgcctgccgc
    10501 ccgaccgatc cgccggcttc ccggggtcca ccaggttccg gccggaacgg tgctggaagt
    10561 agtactcggc acgggaacgt gcaccgccca ccggacctgg gcgccgccgc actcccgccg
    10621 gatcacggcg gaggacgagg cggtggcggc cgtccgccgg gccctggagc atgcggtgcg
    10681 ggtgcgtctg ggcccagagg cacctctggt ggtgctctcc ggcggcatcg actccgccag
    10741 cgtcgcggcg ctggcggacc gggcggccgg cccgatcgac accatctcga tgggcacgga
    10801 cgacgccgat gagttctccc aggcgcggat cgtcaccgaa cacctcggca ccacgcaccg
    10861 ggaactcatc atccccaccg ccgacctgct gcgccgcctc ccgcacacgg tctgggcggc
    10921 ggagtccctg gaccccgaca tcatcgagta cctgctcccg ctgacggccc tgtacctgcg
    10981 cctggacggc actgggcggc gcatcctcac cggctacggc gccgacatcc ccctgggcgg
    11041 tatgcaccgc gaggaccggc tgcccgccct ggacaccgcc ctcgcccacg acatggagac
    11101 cttcgacggc ctcaacgaga tgtctccggt gctctccggc attggcggcc actggtccac
    11161 ccacccttac tgggaccgcg atgtgctgga cctgctggtc tccctggagg cagggatgaa
    11221 gcaccgctac gggcaggaca agtgggtgct gcgggccgcc atgggcgatg tgctgccgca
    11281 ggagaccgtg ctccgcccca agctcggggt gcacgagggc tccggcacca cctcgtcgtt
    11341 cagccggctg ctcaccgacg ccggggtccc cgacgggcgg gtgcaccacg ccaagcgcct
    11401 ggtcgtccag gagttgttcg accaggtggt ggtggccggg cggcaccccg acgaagtggc
    11461 caccgatgat gcggtgcagc tggtcgtcga ccggttggag cgccatgcac agcccatccc
    11521 gtgacggacc cgtcactcag cggacacacg aggagcaacc agggcgtgga acgtatcgac
    11581 atcaccgtct ccccccgcta cgcgcagatc cccaccttca tgcggctgcc gcacgatccc
    11641 gccccgcgcg ggcgggacgt cgtggtcatc ggcgccccgt acgacggcgg caccagctac
    11701 cggccggggg cgcgcttcgg accccgcgcc atccgcaacg agtccgggct gatccacggc
    11761 gtgggcatcg accgcggacc gggcaccttc gccctgatca gctgcgtcga cgccggcgac
    11821 atcgacctga ccccgttcaa catgcacatc gcgatggaca ccgctcagcg acggctgggc
    11881 gaactgctgg tcgacaacgc ggcgttcctt atgctcggtg gcgaccactc gctgaccctc
    11941 gccgcgttgc gagccgtctc cgcgaagcac gggcgtctgg ccgtactcca tctcgatgcg
    12001 cacagtgaca ccaaccccgc cttctacggc ggtgaatacc accatggcac gcctttccgt
    12061 cacgccatcg aggagaagct gatcgatccg cagcggatgg tgcagatcgg catccggggg
    12121 cataacccgg agcccgatgc gctcgactac gcccgcgggc atggcgtgcg catcatcacc
    12181 gccgacgact tcgccgacct cggcaaagac gccaccaccc gactggtccg ggacatcgtc
    12241 ggcgacaccc cgctttacgt gtcggtggac atcgacgtcg tggacccggc ctttgccccc
    12301 ggcaccggga ccccggcccc cggcggcccc gcctcccggg aggtcctggc cctgctgcgc
    12361 ggcgtcgggg acctccagcc ggtcggattc gacgtcatgg aagtgtcgcc gctctacgac
    12421 cacggcggca tcacctcggt cctggccacc gagatcggcg cggaactcct ttaccagtac
    12481 gcccgcgccc acaaccaaga gcacacctag gaaaggaaga taccgtgaca gttgtggact
    12541 gcaccgcacg cgccggtgag ctgcgcgcac tcaccgcgcg gctgccgcag cccccccgcg
    12601 cggacctgta cgccttcctg gactccgcgc agaacgcggc cgccgcgctc cccgacgccc
    12661 tggcaaccgc agtggacacc ttcaacgccg agggctgccg ggacggctac ctgctgctgc
    12721 gcggtctccc ggtggaggac gactcggccc tgccgcccac gccgaccagc accccggctc
    12781 ccgtggaccg tcctctgctg accatggagg ccatgctcgg catagtcggc cgccgcctgg
    12841 gcctgcacac cggctaccag gagctgcgct cggccaccgt ctaccacgac gtgtacccct
    12901 ccccgaacgc ccaccacctg tcctccgaga cctcggagac gctgctggag ttccacacgg
    12961 agatggccta ccaccttcgc cagcccaact acgtgatgct ggcctgttcc cgggctgatc
    13021 acgagaacaa ggcagccacc ctggtcgcct cggtccgcaa ggccctgccg ctgctctcca
    13081 ccgaggtacg cgagcgactc cacgaacgga agatgccgtg ttgcgtggac gtggccttcc
    13141 gcggaggcgt agcggacccg ggggctatcg cccaagtcaa gccgctgtac ggagacccca
    13201 aggatccgta cctcgggtac gaccgcgagc tgctcagccc ctgcgacccc aaggacgtgg
    13261 cggcggtcgc catgctgtcg aaggcgctcg acgaggtcac cgaggcggtg tacctgacgc
    13321 ccggtgacgt gctgatcgtc gacaacttcc gcaccacgca cgcccgcacc ccgttcaccc
    13381 cccgctggga cggccgggac cgatggctgc accgcgtcta catccgcacc gaccgcaacg
    13441 ggcagctctc cggaggggag cgcgcgggcg acgtggtggc cttcaccccg cgcggctgac
    13501 ccgcagcaac gcgccggacc cgcgcgcgaa ggactggaaa tcccccgccg cgaggctccg
    13561 ttgcgcaacg ccggcgccgg agtgcacgag catggtatgg atcaatggaa cggcgcttcg
    13621 ccgcaccctc gccacccagg agacgaacag gcatgacgga cagcgaaacc tacgaaccgc
    13681 gggggttctc ggtgcacacc gcgccggtgg gcctccggga cgacggacgg gacgacttca
    13741 ccgtcctgct ctccaccgca ccggccacgg tgagcgcggt cttcacccgc tcccgtttcg
    13801 cggggcccag cgtgcggctc agccgtgccg ccgccgccga ccaccgtgcc cgaggtgtgg
    13861 tggtgctcgc ccgcaacgcc aacgtcgcca ccggtgccga gggcgagcgc aacgcccgcg
    13921 aggtgcgcgc cttggtggcc cgggcgtccg ggctatcgga cgaggagctg ctgatcgcct
    13981 ccaccggcgt catcggccac cagtacccga tgccggccct ccgcgaccac ctgaagacgc
    14041 tggccgtacc gtttcccgag ggtggtttcg accgggcagc ccgggccatc atgaccactg
    14101 acacccggcc caagcatgct ttccggcgga tcggcaacgc caccttggtc gggatcgcca
    14161 agggggtcgg gatgatggag cccgacatgg ccacgctgct caccttcttc gctaccgacg
    14221 cccggctgga cccggcggaa caggaccgcg tattccgccg ggtgatggac cgtacgttca
    14281 acgccgtcag catcgacacc gacacgtcca ccagcgacag cgcggcgctg ttcgccaacg
    14341 gcctggcggg cgaggtggac ccggttgcct tcgaggaggc cctgtacgag gtggcgctga
    14401 cgctggtgaa gggcatcgcc cgggacggcg agggcgcggg caagctgatc gaggtccggg
    14461 tccacggggc gcgggacgac gcgcaggcca aacgggtcgg caaggccgta gtcaactccc
    14521 cgctggtgaa gaccgcggtg cacggcggcg accccaactg gggccgggtc gccatggcga
    14581 tcggcaagtg ctccggcgac accgacatcg agcaggagaa ggtggtcatc cgcttcggcg
    14641 aggtagccgt ctacccacct gcccggcagg gtgcgcggag cgaggagggg gtgcgggccg
    14701 ccgtcgccac cgaactggcc ggcagcgagg tggtcatcgg catcgacctc ggcatcgcgg
    14761 acggtgcgtt caccgtgtac ggctgcgacc tgaccgaggg ctacgtgcgg ctcaacgcgg
    14821 actactcgac ctgatcggcc cgcaccgtcg caggccagcg ggccaggagc cgacgcagtt
    14881 cgccaccgac gaactcccgg tcggcggcgt ccgcgccggc tcccgcgagg tgcccccaca
    14941 cgcccgggac caccttcagc gcagcgcggg ggagcacacc cgcgacccgc tcctcgtccg
    15001 cgacggcgaa gcactggtcc aaggcgccgg gcagcagcac cgcctcggcc gtgaccgagg
    15061 ccagtgcggc gtccgcgctg ccgccgaacc cgggggtcgc gcccacatcg gcgctctccc
    15121 aggtgcgcac catggccagc aggtccgcgg tggccgggcc ggccacgaag aactcctccc
    15181 agaagttggt gaggtactcc tccctggtgg cgaaccccag ctcctggtac gcccgttggg
    15241 cccagaaggg gtgcgaggcc ccccatccgg cgaagacccg cccggcggcc cgtcgtcccc
    15301 gctccgcgcc gccgtcggag gccagcgcgg cggccagacc ggccaggaag acctggttgt
    15361 gctcgctggt caccggggag ccgcagatcg gcgcgatccg gcggactatc cgcgggtggg
    15421 acaccgccca ctggtaggtg tgtgctgcgc ccatcgacca gccggtgacc agggccagct
    15481 cccggacgcc caactgctcg gtcagcagcc ggtgctgcgc ggcgacgttg tcctgcgggg
    15541 tgatcagcgg gaagtccgcc cccgaaggat ggttgctggg cgagctggag accccgttgc
    15601 cgaacagccc cacggtgatg acgcagtacc ggctggtgtc cagcggtcgg cccttgccga
    15661 tcagccagtc gtagccggtg tggtcaccgc cgaagaacga cgggcacagc acggcgttgg
    15721 cgccgtccgc gtccagcgtc ccgtgcacgg cgtagccgat cctggcgtcg gtgaggagct
    15781 cgccgctgag cagcggcagc gcgtcgaggt cgaaaacgcg gtggtccacc gcggccctcc
    15841 ttgatggtgt ggctgtccgg tgtggccggc tgccgtggag gagccgcccg tcctcgtacc
    15901 agcggcccct cggtaccggc tccgtacaca tgcctccgtg agcggatgaa ccgagcttcc
    15961 ctcagagcca gttgggggcg atctcggtgg accacagctc caggctgcgc atctgcacgt
    16021 cgtgcgggat cagcccggag tactggcact gcagcaggta ctccgggtcg tgctgctcca
    16081 ccagcttctc gatcttgcgg ttgatgtcgt ccggggtgcc gacccactcc aggccccggt
    16141 cgaccagcgt cccgtagtcc gaaccgatcg gcccggattc cccgacgttc cgcagcgcct
    16201 cggtgaagcc catggggccg aaccagttct cgaagatgaa accgccgccg cgggccgccc
    16261 agtggtgggc ctcatcggcg tcccgggaca ccaagacatc cttcatcaca cccacccgct
    16321 cgccgcgccg cagcgtgccg tgcccggccg cctcggcctc ctcctggtag aggtccatca
    16381 ggcggcggac gactcggtcg tcggtgttca tcacgatcgg caccacgccc tcccgggcac
    16441 aaaaccggaa ggtgtcctcg ctgaagctga acggctgaaa caccggaggg tgcggccgct
    16501 ggtacggctt gggggcgatg cccacctcct ggaccgtgcc gttgtcgtcc agcccgcggc
    16561 cgtaccggcg caccgcctca taggggaact ccaggtcctt caccgggatc gtccaccggg
    16621 cgccggagtg cgagaaggtc tcggtcgtcc acgccttctt gacgatctcc cagtgctcct
    16681 cgaagagcgc gcgattgcgt cggtcgttct caccggcgtc ggagagcgtg ccgcccacgc
    16741 cgtacgtctg gcccatgacc tcggcccagc gcttctggaa accccgcgcg atgccgacga
    16801 aggcgcggcc gcgggtcatg tggtcgagca tcgccaggtc ctcggcgagc cgcagcggat
    16861 tgtggaaggg caggacgttg gccatctgac cgactcggat gtgctgggtc tgcatggcca
    16921 gatacagacc cagcatgatc ggattgttgg agacctcgaa gccctcgacg tggaagtggt
    16981 gctcggtgaa ggacagaccc cagtagccta gttcgtcggc cgcctgcgcc tgacgggtga
    17041 gctgccggag catgttctgg tagttctgcg ggttgacgcc cgacatgccg cgcaggatct
    17101 gggcatggct gccgaccgtg ggcagataga agaggatgga cttcactgtg gtcctgcctt
    17161 tcgagatctg ggccggagtt gacatcggca aggaacgcca ccactgcgtg gtgatcaagg
    17221 cggacggtga acggctggcc cgcatccgac gtgatatcgg cctgctgcgt cgcggcgatg
    17281 agatcgccgt cgacctgcgc ccccggcgcc cggacgtggc cttcgaccgc accgtcagat
    17341 caaccgtctg cgtgctcagc tgctgggggt cttctccgcg ttggagcggt cgctggatct
    17401 ggtcaacaag ggtccggtga tgctgctgac cggctaccag atcccggccg cgatccgacg
    17461 cgcaggcgtg aagcggatcg agacctggtt gaagaaccgc aaggtccgcg gcgccgccgc
    17521 gctctcgaag cgggcagtgg aggccgtcca ggcccagcac accgcgcttc ctggcgagaa
    17581 gccggccgcc gccatggtgg ctcgcctcgc gaagggggtg atggccctcg atgaggagat
    17641 cgctgaactc gacgccacga tagaggccat gtttcacgag catccgcacg ccgagatgat
    17701 ccgcagtctg cccggcatgg gccccaggct cggcgctggg ttccttgccg cgaccggcgg
    17761 cgacgtggac gccttcggaa gcgccgaccg cctggccggc ttcgccggcc tggcccacag
    17821 accccgcgac tccggccgcg tcagcggcaa cctgcgcaga cccaagcgat accaccgagg
    17881 actgctgcgg agcatgtacc tttcggcgtt gatcagcatc actgcatgcc ccgactccga
    17941 ggcgtgctac cagcgcaagc ggagcgaggg caagggacac aagcaggccc tgctcgccct
    18001 tgcccggcgc cggctcaatg tcctgtgggc gatgatccgt gacggacagt gctaccaagg
    18061 ttcacctccc gtcacagtgg cggcttgaca tcacgattgg gaagtccttt cggttcgcag
    18121 cgccgacgcg taactgtgcg ccgaaggcgt ctcgaccgtc tcaccgcact cttgacatcc
    18181 atttgatggg gcgtctgtcg ggcggccccg tccaaccggt acctgccggg ccggagtcgg
    18241 cccgggtgca gcggaacatc cagcgggcaa caagccttcg cagagatcct cggaacgcac
    18301 catcaccgtt cctaaggagc ccgccttgac ctcagcaccc tccaccccgc cgggtgcgcc
    18361 cggcaccgag ctcgccgccg cggaccgtgc cacgctcatc catcccacgc tggccgcgca
    18421 ccgcacggac cggaccgtgc tggtttccgg ttccggcagc cgggtccggg acgcccgcgg
    18481 tcgggagtac ctggacgcgt cagcggcgct gagcgtgatc caagtgggcc acgggcgcca
    18541 ggagctcgcg caggcagcag cggagcagat gacccgtctc ggctacttcc acacctgggg
    18601 caccgtcagt aacgaccgcg cggtggagct ggccgcccgg ctggtccgac tgagcccgga
    18661 gccgctgtgc cgggtgtact tcaccagtgg cggcgccgag ggcaacgaga tcgcgctgcg
    18721 gatggcccgt ctctaccacc accggcgcgg cgagccgcag cggacctgga tcctctcccg
    18781 tcagacggct taccacggca tcggctacgg cagcggcgga gtctccggat tcccggtcta
    18841 ccacgagggg ttcgggccct cgctgccgga cgtccacttc ctgaccccac cgcacccgta
    18901 ccgccgggag ctgttcgccg gcgccgacgt gaccgacttc tgtctggccg aactgcgcga
    18961 gaccatcgaa cggatcggac cggagcggat cgccgcgatg atcggcgaac cggccatggc
    19021 tgttgccggc gcggtcgttc cgcccgccga ctactggccg cgggtagccg acctgctgcg
    19081 ctcctacggc gtcctgctga tctccgacga ggtgatcacg gcctacgggc gcaccgggca
    19141 ctggttcgcc gcggagcact tcggcgtggt tcccgacatc atggtcaccg ccaagggcat
    19201 cacctccggt tacgtgccgc acggcgccgt cctcacgact gaggaggtcg cggccgaggt
    19261 gaccggcgac cacggctttc ccatcggcta cacctacacc gggcatccga cggcctgtgc
    19321 tgtggcgctg gccaatctcg acatcatcga tcgcgagggg ctggtggcca acgccaccgc
    19381 gatcggcgac tacctggggt cgcggctggc ggagctggcc gggctgccgg tcgtcgggga
    19441 ggtccggcag ctcggcctga tgctggccgt ggagctggtg accgaccagc agagccggcg
    19501 actgctgacg ggcggcaccg tcgcgctggc ggacgcgttg caggagcagg ccgggatcct
    19561 gctgcgcacc accccgtacg cactcctgat caatccgccg ctggtcttca cccgcgagga
    19621 cgcggacgaa ctcgtggacg ggctccgttc cgtgctcagc cgcaccggcc cggacgggca
    19681 ggtgcactga ccgcaccggc acggacgcac ggtgtgcggc cggacgtcaa acggttctgc
    19741 aagcgtgcgc caaggccggc ggggcggcct cgcggagctg ttccggggtg cgaggcgaac
    19801 gctggccgcc gctctggagg cagaaggcaa cgcccatatg gccgagttgg ccgatcagcg
    19861 cgaccggacc ggccgccgtt cggtggttcg cgacggctgt cgccgggcgt gagaggtgac
    19921 cacggccgcc ggcccggtcg aggcgaggcc ccgcgggtca atgaccgccg cgtcgacgag
    19981 tccaccggcg agcgcaagcg gttctcttcg gtggtctccc tcagccttcg gtcagcacga
    20041 aacccgctgg cggccgatct tgcctccacg gggacctatc ggctaccacc acgtcaccac
    20101 gacccggctc gcgtcgcccc cgaggccgga ggaacctgga gccgatacgc ccccggtaac
    20161 cacagacggt cgccgaccgg ctgggccccg cggagaacgg gagacagttg atctgccggc
    20221 tcatcaggga ccgacaccgt gagatccgga ccggaactcc cttcggggca ccgacggaac
    20281 tcggtgacca ggacgatgca tccttgcatg ctgatcgtat ccacgctgtc ggatcatttc
    20341 ccgccgcacg cggcggttca cgctgtcgag ctgcgccgcc tcgcggcgag ctcgctggca
    20401 ccgagccgga gtttcgtcag tgtccccctt cgcgatccag gatctcggct ccaccaacgg
    20461 catcgtgctg gacaagcagc atgccacccg cagtacgctc cccgaacgcg cagaaggagc
    20521 ccttgcgtcc ccaactggtg tcccaggcca cgatgttggg agggctgccc gcgcggtgtt
    20581 ccaggcacgc ctgcagacga agggaacgcc gtatggagga gagtaacccg agccgctggt
    20641 ggaggcacct gacccgtcag aacaggtcgc gcacggagaa aacggatcac ctgcggaaat
    20701 gggctggcca gcaaggacgg agtgtcccgg gggagttcct acggggcgcg gcatacaagg
    20761 tcggcagtgg cgcagtgacc ctgctcgtcc tgtggtggga gacccgccac tgacactcga
    20821 gggcggaccc accacttggc gggcccgctt catgttgcac gtcagtacag acgctgacgc
    20881 ccccggcaac cacacacggt caccgaggtc gctcgcgcat ggactctgag ggtcaagtgg
    20941 tcttgtggct ccattggggc ccgaccacgg tccactccgt gtcccactgg tggatgcgcc
    21001 gacggtcgag ccaccaccgc ccagcgctcc cgatcccgat caccaagccg ctcagggcga
    21061 gggcggcgga ggcaccaagg agtcccgcct cggcggccgc cttggcgggc gtcggcggct
    21121 gtgtactcag cttcccctgg gcgtcgatcc agattctgac cgtggagccg gcctctttcc
    21181 cggttgccac caccgtcatg ccgttgcgcg tggagccgtc ggagttagtc cagcggaccc
    21241 ttgccgagga aaggtctctg tccagccccg acatcgcggg acgcgggacg tcatcgagca
    21301 gaacggcgcg gacgggggtc cggtcggccc gctgctgggc gaagacccgg tcggcggcgt
    21361 gggccgtcac cacaccggcc gccgtgccac ccaccgcgat gagcccccat acggccagca
    21421 ggagccatgc ctcgaggatg tcgtcacgtc gccggatcgg gttgttccgc catcgccaca
    21481 gcggcaccct cgttcgcctg cgcttcccgt tggcgggctt gccctcgtgc atctctccgc
    21541 acctcctcgt cgtcacacac ccgaagatga cagccacagc cttgccgtgg catgggccga
    21601 tcaggcggaa gtggagggcc gatcgggacc atggaagccg cgtaccccaa ccgagccgac
    21661 ccgaccgggt agtggagagc cgccgatggg tgcacccggg cccggacgac ttcagcgaca
    21721 tcggcatacc gcaagcggcg ctgtgccgca ggacgcacac gagaaactgc cgatgcgaga
    21781 cttcaccgca caacggcact cccagtggct ccccgcccag cctttcgact cctatcccgt
    21841 gttggccccg ctgaccaccg agcacgaccg gcccagcgac aggctgcgcg ccggacaggc
    21901 gttggagcac cttctgttgg tggccacggc gcacggcctg tgagcctccc tgctgcgcca
    21961 gccgagggag tggcccgacc ggcgccgcga cgtgagcccg tgccgcatct caccgggcat
    22021 gtgcagatgc tgattcgcct cgggtacggc ccgcagggcc ccggccactg cgcgacatac
    22081 gccggatccg gtgtggtgac gctcgacgac caagccttcg gggtagccat gggcctggag
    22141 ccacggccac ccgaaggctt ggcggccggc cctccacccc atgcgggtcg cgcctgcggc
    22201 cttgtcagcc cgctgcggcg gtgaaggccc cggcgggcac agcggacacg gcttcgggca
    22261 ggcgctcaca gatctcgaac acgccatcca gtcccgcacc gctcagaatt cgaaggaatt
    22321 ggctgctgtc agtgacgagg cgcagccgac cgtgccgttc catgagcctg ttccgtgccc
    22381 ggcacaacac ccgcagcccg gtgcagtcga tgaaggacac ggcgcgaagg tccaccacga
    22441 ggtcggagag gacggcggcc gtcaactcgt ccaggcgtgc ctcaaggggc ggtgccgtga
    22501 ggatgtcgat ctcaccgcgc agctccacga cggtcgtcct gccgacggca cggtcggtgc
    22561 ggcggggtgc ggacgtgatg agcgttttga ccatggccag aggaaacccg ggccgatggg
    22621 cgcgccggaa gggccgttcg gccccgcttc gccgcaacga ttcctcgggc cgctctccgc
    22681 ccggggcggg acccgtggcc ctcacccgcg gccgccgacg ggctcagcat ggagtgtgat
    22741 tccccgaccg ggtgaaagac gggctgactc atgtacccga acgatggtat gcgcgaactt
    22801 ggttgtcacg agtgcctgcg cctgctggcg acggcgccca tcggccggat cgtccacacg
    22861 cgccaggcac tgcccgcggt cgtgccggtc aacttcggtc tggacaacga tggagcggtg
    22921 ctgctgcgca cctctgcggg ctccgagctg gcccgcgcgg tcgacggcgc ggtcgtcgac
    22981 ttcgaggcgg acgcagtcga cgcggacacg cactccggct ggagcgtcgt cgtcacggac
    23041 cgggccgaga tcgtgacgga tccggctgag gcggcgcgcc tggagcggat cggcccgcgc
    23101 tcctgggctc cgttgcccga ggaggtcttc gtccgcatcg agccagaact ggtcaccggg
    23161 cgtgaactcg tcggggggcg gaccatgtac ggcctggacc tctccgcctg accgctgcgc
    23221 atcacctgct cgcgccctgg tccgaacggc ccaatggcgg gggccggacg gcgtggcgag
    23281 gggttcccgc aggaccctgc cccgggccgg ggcacgcgag gagcatcgtc agcggagtcg
    23341 gcccacggaa ccgtccgggg gcggtgtcgc gcatgatgcg gaggcagtga tgaccgtggc
    23401 aacccatccc gacgtggacg ctcccgccga tgcctggcgt ggtttcgcag gccggcgctg
    23461 gcgcgaccgg atcgacgtac gcgacttcat ccaggccaa
//
