LOCUS       NZ_CP054916            22000 bp    DNA     linear   CON 31-JUL-2024
DEFINITION  Streptomyces sp. NA02950 chromosome, complete genome.
ACCESSION   NZ_CP054916
VERSION     NZ_CP054916.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. NA02950
  ORGANISM  Streptomyces sp. NA02950
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9619720)
  AUTHORS   Zhang,B., Shi,J. and Ge,H.
  TITLE     Genome mining for natural products
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9619720)
  AUTHORS   Zhang,B., Shi,J. and Ge,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUN-2020) Institute of Functional Biomolecules, State
            Key Laboratory of Pharmaceutical Biotechnology, Nanjing University,
            No.163 Xianlin Avenue, Nanjing, Jiangsu 210046, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. v2.05
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013364155.1-RS_2024_07_31
            Annotation Date                   :: 07/31/2024 07:40:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,566
            CDSs (total)                      :: 8,476
            Genes (coding)                    :: 8,147
            CDSs (with protein)               :: 8,147
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 329
            CDSs (without protein)            :: 329
            Pseudo Genes (ambiguous residues) :: 0 of 329
            Pseudo Genes (frameshifted)       :: 152 of 329
            Pseudo Genes (incomplete)         :: 270 of 329
            Pseudo Genes (internal stop)      :: 20 of 329
            Pseudo Genes (multiple problems)  :: 101 of 329
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:05:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1539642
            Orig. end                         :: 1561642
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054916.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22000
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="10"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22000
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22000
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12000](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12000
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(1329..1931)
                     /gene="ureA"
                     /locus_tag="HUT19_RS06170"
                     /old_locus_tag="HUT19_06170"
     CDS             complement(1329..1931)
                     /EC_number="3.5.1.5"
                     /GO_function="GO:0009039 - urease activity [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0019627 - urea metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ureA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016824089.1"
                     /locus_tag="HUT19_RS06170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06170"
                     /product="urease subunit gamma"
                     /protein_id="WP_176179478.1"
                     /transl_table=11
                     /translation="MHLTPRELERVQLFTVAELARRRRARGRRLNAPEAIALICDEVLE
                     AAWDGASLDEVIEAGRSLLTVDDVLEGVPALVGTVQVEALFPSGTSLVAVENPIVGGAA
                     DHAPGAVRTAAEPVLINAGRPRLRLTIRNNGDRTVYLSSHYPLAEANSALELDREAAAG
                     MRLDVAAGTALAFEPGTEREVDLVAARHDGDEPEESA"
     misc_feature    complement(1896..1909)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     gene            2053..3255
                     /locus_tag="HUT19_RS06175"
                     /old_locus_tag="HUT19_06175"
     CDS             2053..3255
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037653.4"
                     /locus_tag="HUT19_RS06175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06175"
                     /product="CdaR family transcriptional regulator"
                     /protein_id="WP_176179479.1"
                     /transl_table=11
                     /translation="MHNAAVAFPPPDPRIAELARECLDDLDGLIELWIDVVGPVRRTYA
                     DRVPDADFRDSARDALEMLLRTVAELAVPEHIAEVSERVGTRRARQGVPLESLLDAARL
                     DFRVVWTALVRRAEDRNMTHLVASAYYVWEAVERHVTGIMTAYQRTVLEMGRRAEDERQ
                     MWFARLMDCDGRNPTVVGDTALALGFQVSGEYVCAAAAPQYGAALRRAAADLRTAGIPV
                     QQQALDSAVVLTAQLGPRTTADTILGHLGETPCGVSSAADRLADVPRAIRLAITTARSL
                     PMDARGPRWLRDSWLDVLVHHTSDLAHDLADDVLGGLGRPDITDAEKDRLLRTVHVHLT
                     GNGAIADTAAAVYCHRNTVQHRFNRFRELTGHDVRRPEDAALIALALRARERRARTEAT
                     G"
     gene            complement(3500..4678)
                     /locus_tag="HUT19_RS06180"
                     /old_locus_tag="HUT19_06180"
     CDS             complement(3500..4678)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069051.1"
                     /locus_tag="HUT19_RS06180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06180"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_176179480.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 9.1e-24, bitscore:
                     83.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 9e-21, bitscore:
                     72.8, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4.6e-30, bitscore:
                     103.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLEFTPAQRRLRAELRTYFTELVPDNAYARYGDPAGQKRFYRET
                     IRRLGADRWLGVGWPQEYGGRGLGPVEQFIFFDEAAQAGVPLPLMALNTVGPTLMRYGT
                     EEQKAYFLPKILSGEIDFAIGYSEPDAGTDLASLKTRAVRDGDHYVVNGQKTWTTNGDT
                     ADWVWLAVRTDPEAKPHKGISILLVPTDDPGYSCTPITTLASHDTTASYYENIRVPADR
                     RVGEENEGWRMITTQLNYERVTLAAHGTMAIRALRGVQRWAADTKLADGRRVIDLGWVR
                     ARLARTHARLDAMKLLNWQMVDALQRETLTPQDASAVKVYGSEARRDAYAWLMEIVGAA
                     GPLKEGAAGAVLHGELERGYRSSVVFTFGGGNNEVQREIISWIGLGMPRVRR"
     misc_feature    complement(4663..4677)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.73"
                     /tool="antismash"
     misc_feature    4903..4916
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            complement(4947..7226)
                     /locus_tag="HUT19_RS06185"
                     /old_locus_tag="HUT19_06185"
     CDS             complement(4947..7226)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058770.1"
                     /locus_tag="HUT19_RS06185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06185"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_176179481.1"
                     /transl_table=11
                     /translation="MENTAAPAAAAARPRPHSSEPPRYRRPAPWLGLVALAYAVVQLAV
                     VIPHTGHALGWDESVYVSQVDPRNPAAFFSAPRSRGISLLVAPIVAATSSIPVLRVLLT
                     VLSALALYTSFRVWTRLLPRTTVALAALLFSGLWITMISGPAVMPNLWVALGAVATVGW
                     FLRVPADRNARWWLAAVLAGVTLVRTPDGGWLGLPLLVAAIAVRTWRPALPAVVGGLLL
                     GAAQWIGEAYDRFGGITQRLDVSSDVEGGMGLHFAVGAALRSLNGPQLCRPCEVPLRHP
                     ELTVWWLALPLLTAVALVAALRDRHRRRTRVRVGLGRPEPRRAPGLPTTLLPVICAGAL
                     ALPYLLLIDYSAPRFLMPTYALLALPIAGLVFRAVRIAKSPRHMAVALGVVVALQVASQ
                     YAVLSHAAGQSDTVNGRYRTAADALARMGLRPPCLVIGDRALPIAYHAGCSSAQTSGNN
                     KSLSTSALLRRAGREPTALLVKRGHGRPPSYARDWIAYPLRGTEWNAHLPVEQAREMEA
                     RKSGQETSGKPGTMGGMTMNPTTSWSGFQAAEPGFATAAEDRFGRYRHHVLATLRQDGA
                     PRLTPFEVDFRDGELWLGMMSESRKALDLRRDPRFSVQANPGPEAGPVDGDVRVSGRAV
                     EVTDPEVIARYAEAVRPPEPFHLFRAEVSEVVHTSVEGSELVLRTWRPGEPVRILRRGG
                     DDGPPRVETPPGDGGPAPTEGLSSTDGTSSTDGPAPTNGPPREESPPRYETVPSDASVP
                     PGMERD"
     misc_feature    7253..7267
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.81"
                     /tool="antismash"
     misc_feature    7295..7305
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    7368..7383
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.98"
                     /tool="antismash"
     gene            7369..8361
                     /gene="dhaK"
                     /locus_tag="HUT19_RS06190"
                     /old_locus_tag="HUT19_06190"
     CDS             7369..8361
                     /EC_number="2.7.1.121"
                     /GO_function="GO:0004371 - glycerone kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dhaK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173709.1"
                     /locus_tag="HUT19_RS06190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06190"
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="WP_176179482.1"
                     /transl_table=11
                     /translation="MKMLINVAESVVADALRGMAASHPELTVDVENRVIVRRDAPVADK
                     VALVSGGGSGHEPLHGGFVGRGMLDAACPGEVFTSPVPDQMVRAATAVDSGKGVLFIVK
                     NYTGDVLNFDMAAELAEDEGVQVAKVLVNDDVAVTDSLYTAGRRGTGATLFVEKIAGAA
                     AEEGMPLERVEAVARRVNELSRSFGVALSACSTPGKGGPTFDLPPGELELGVGIHGEPG
                     RERRAMMTSREIADYAVNAVLDDLPPDNPVLVLVNGMGATPHLELYGFAAEVHRVLGER
                     RIAVARTLVGNYVTSLDMAGASVTLCQVDEELLRLWDAPVRTAGLRWGC"
     misc_feature    complement(7370..7384)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.24"
                     /tool="antismash"
     misc_feature    complement(7371..7386)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.07"
                     /tool="antismash"
     misc_feature    7374..7389
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.07"
                     /tool="antismash"
     gene            8422..9054
                     /gene="dhaL"
                     /locus_tag="HUT19_RS06195"
                     /old_locus_tag="HUT19_06195"
     CDS             8422..9054
                     /EC_number="2.7.1.121"
                     /GO_function="GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dhaL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058772.1"
                     /locus_tag="HUT19_RS06195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06195"
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="WP_254885460.1"
                     /transl_table=11
                     /translation="MSSSEPAVEHVLDTPFFHRWLSAAAASVTRDAARLTELDSAIGDA
                     DHGTNMQRGFAAVTEALDKERPGSPGATLILAGRQLISKVGGASGPLYGTLLRRAGKAL
                     GDAEEITPQQLTDALRAGADAVAQLGGAAPGDKTMLDALLPAVEALAAGGSFAAAAEAA
                     EKGALATTPMLARKGRASYLGERSIGHQDPGAASSALIVAALTEAAR"
     misc_feature    complement(8444..8459)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.78"
                     /tool="antismash"
     gene            9051..9467
                     /gene="dhaM"
                     /locus_tag="HUT19_RS06200"
                     /old_locus_tag="HUT19_06200"
     CDS             9051..9467
                     /EC_number="2.7.1.121"
                     /GO_function="GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="dhaM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173711.1"
                     /locus_tag="HUT19_RS06200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06200"
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="WP_176179483.1"
                     /transl_table=11
                     /translation="MSEETQEKLVGIVLVSHSAAVAESIAEMAAGLAGGVDAPVRAAGG
                     NPDGGLGTSPERIIEAARAVDQGAGVAVLVDLGSAVLAVKSLLAEGDELPDGAQLVDAP
                     LVEGAVAAVVTASTGADVDAVAQAASEAYDYRKV"
     misc_feature    9611..9631
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.5"
                     /tool="antismash"
     misc_feature    9786..9800
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.91"
                     /tool="antismash"
     gene            10001..11080
                     /locus_tag="HUT19_RS06205"
                     /old_locus_tag="HUT19_06205"
     CDS             10001..11080
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058774.1"
                     /locus_tag="HUT19_RS06205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06205"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_176179484.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3e-47, bitscore:
                     160.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPTLSPDFLDTDAIRGAVERVLDDFLTAKSRSPAPPPLPSLPR
                     LLGDFLAGGKRMRPLLCVTGWRAVGGAGDPGPVLRVAAGLEMFHAFALLHDDVMDDSPV
                     RRGRPAMHRTLAALGAAHLSQERIERSGVNGAVLLGDLALLWSDEILHTAGLTPVQLAA
                     VLSPLSTMRTEVMLGQFLDLRATGTLTDDVEATLTVNRYKTATYTVERPLHIGAAVAGA
                     GPGAMDALTRYALPLGEAFQLRDDLIGVYGTEESTGKSPLDDLRAGKNTTLTALALRAS
                     DRVQDAQLRELLGDPLLDEKQAAIVREIFDATGARETVERMIEDRGRQALRALDDAPFT
                     PDAVTALRRLVRMATVRTS"
     misc_feature    10235..10237
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11077..12000
                     /locus_tag="HUT19_RS06210"
                     /old_locus_tag="HUT19_06210"
     CDS             11077..12000
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058775.1"
                     /locus_tag="HUT19_RS06210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06210"
                     /product="hypothetical protein"
                     /protein_id="WP_176179485.1"
                     /sec_met_domain="T1TS (E-value: 4.8e-10, bitscore: 38.3,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTADLFEAGPTDLGTPSLRPYREECTRRFAELFARHIGHRPVPRT
                     LTPEELREVIAACNAAVAPLGTTVSDERWISYLEVVCWSQSARHIRDMEAFKAVCVLNC
                     VTFVWDDMDPALHDFELFLPRLRGICESYYAEEDAWFAYEAARAFVTSDHMFRDSPLKA
                     ALCRTSPEQYFRFRVTDVGVDFWMKMSYPVYRHREFTEHAKTGLAARMTTRGLAVVNDF
                     YSYDREVSLGQITNCFRLCDVSDEAVFKEFFQDRLDDITEDIRCITAFDEVSRDILLDL
                     VYGNFIWTTGSERYRAAVNHVNSRIR"
     gene            12027..13385
                     /locus_tag="HUT19_RS06215"
                     /old_locus_tag="HUT19_06215"
     CDS             12027..13385
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000062: Hydroxylation (75% identity)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058777.1"
                     /locus_tag="HUT19_RS06215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06215"
                     /product="cytochrome P450"
                     /protein_id="WP_176179486.1"
                     /sec_met_domain="p450 (E-value: 7.9e-77, bitscore: 257.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTAQHTVTHGWQVADAPGGLPLIGHALRLARRPLGFLASLPAHG
                     DLVELRLGPQRVHLPCHPELVQQVLLNGRVYDSGGPVKDKARQILGNGLITAGRADHRR
                     QRRLVQPAFHTARIEGYAEVMRHECEAVAGSWTTGRAIDVSREMQTLTTRITARALFTT
                     DMAPHAVAEVQHCLRTVVRGAYHRAIDPTGLVARLPLTANRTFETALSRLHRRIDRLIA
                     DYRATGGDRGDLLSALFAARDEGTGERLSEREVHDQVLTLLLAGIETTAAALTWTWFLL
                     GRNPAAQAALHAEVDAVVGERTPGYADVPRLAYTQRVFTEALRLFPPAWIITRTTTEPT
                     ELAGRRLPRGADVLISPYMLHRDARLFPRPESFDPDRWLPERAKDVARGSYLPFGAGSR
                     KCVGDVFGMTEATLALAAVARRWRLRPVPGTRLRPRPQMSLTAGPLAMVPEPR"
     misc_feature    13495..13508
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.95"
                     /tool="antismash"
     gene            13548..14231
                     /locus_tag="HUT19_RS06220"
                     /old_locus_tag="HUT19_06220"
     CDS             13548..14231
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058778.1"
                     /locus_tag="HUT19_RS06220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06220"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_176179487.1"
                     /transl_table=11
                     /translation="MGDRVNKATPLRRDAQRNREMLIAAAREIYADQGVDAPLDDIARR
                     AGVGSATLYRRFAGRAELIEAVFGESLKDILRASLEARQSIDAWGGLTTYLERIFTLLV
                     TDRGTNDLMTTAIQGVPSLDSLRTEHRKTIDVLLRRAQKEGAVRDDVTAEDFLFLTVML
                     GRTVPGAAVAAPYAWRRYLAMLLDGLRPEAAGPLPAPALTPDQFATAVAHLGRPRRPRQ
                     GRTEH"
     gene            14378..15799
                     /locus_tag="HUT19_RS06225"
                     /old_locus_tag="HUT19_06225"
     CDS             14378..15799
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1074: major
                     facilitator family transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136951.1"
                     /locus_tag="HUT19_RS06225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06225"
                     /product="MFS transporter"
                     /protein_id="WP_176186538.1"
                     /transl_table=11
                     /translation="MSMAAPAPPAPARLRRIVAASLIGTTIEWYDFFLYGSAAALVFNK
                     LFFPDSDPLVGTLLSFLTYAVGFAARPVGALVFGHYGDRLGRKKLLILSLLLMGGATCA
                     IGLLPTHATVGSAAPVLLTALRLVQGFALGGEWGGAVLLVSEHGDARRRGFWASWPQTG
                     APAGQLLATGVLSALTALLSDAAFESWGWRVPFLLSGVLVLVGLWIRLSVDESPVFQAA
                     LAQAEARKAEAGRQPDAAEKLPLVAVLRHHWRDVLIAMGARMAENISYYVITAFVLVYA
                     TSDHVDLGKQTALNAVLIASAVHFAVIPAWGALSDRIGRRPVYLLGAAGVGAWAFPFFH
                     LIDTRGFGALLLAVTVGLVFHGAMYAPQAAFFSEMFATRMRYSGASIGAQFSSVAAGAP
                     APLIATALLADYDSATPIALYVIAAALITLVAVGAAQETRDRDLTRIEPSAPGGERATG
                     TLDAAESTPRSASAS"
     gene            complement(15904..17874)
                     /locus_tag="HUT19_RS06230"
                     /old_locus_tag="HUT19_06230"
     CDS             complement(15904..17874)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017949273.1"
                     /locus_tag="HUT19_RS06230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06230"
                     /product="GAF domain-containing protein"
                     /protein_id="WP_176179488.1"
                     /transl_table=11
                     /translation="MADDPPETPYLELLARGAPAEAYERPGLRARADKAPADRLAALER
                     AKLLALRVRGELEGRRRREAELSALFETAHDLAGLRDLDAVLQAIVQRARSLLGTEVAY
                     LTLHDPSAGDTYMRVTDGSVSARFQQLRLGMGEGLGGLVAQTARPYVTDSYFDDARFQH
                     THTIDASVRDEGLVAILGVPLLLGSGVIGVLFAADRRARVFEREQIALLASFAAHAAVA
                     IDTANLLAETRSALAELEAANEIIRDRSAVIERASDVHDRLTALVLRGGGVHDVATAVA
                     EVLSGSVEFVEAGGAPAAAVDRSRADGHAVRHGEDWIAAVSAGGQLLGALVLHGHPGLD
                     PVDQRTLERAAVVTSLLQLARRSAGEAEQRVRGELLDDLLDAPDREPRLLRERAARLRA
                     DLDAPHVVLAAGLDAPATAGAAGARGASGASGADPGGGAPAEEAADRQRLWSAASHLAA
                     TGQGLAAARDGGTVLLLPLAEGDTADALARRTARQLGTALRAPVTVGASSPVPEPAVRP
                     GEVASGYAEARRCLAALRVLGRSGQGAAAEDFGFLGLLLGATRDGVPDGARVQDFVHRT
                     IGAVLDYDTRRGTDLVRTLDAYYASGMSPARTKDELHVHVNTVAQRLERVGRLLGPDWQ
                     SPSRALEIQLALRLHRLASAR"
     gene            complement(17991..18830)
                     /locus_tag="HUT19_RS06235"
                     /old_locus_tag="HUT19_06235"
     CDS             complement(17991..18830)
                     /EC_number="1.1.1.30"
                     /GO_function="GO:0003858 - 3-hydroxybutyrate dehydrogenase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136953.1"
                     /locus_tag="HUT19_RS06235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06235"
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="WP_254885461.1"
                     /transl_table=11
                     /translation="MSAATPSAPATPSAPAPVSGPAPGAAALDLTGRTALVTGAAGGIG
                     RACTLRLAAAGATVRAVDLDAEGLARLVAKAPAGPGTVEARALDLTDLDAAEQAAAGTD
                     ILVNNAGLQLVRPIEDFPPEVFSRVLTVMLEAPFRLVRGALPHMYGQGWGRIVNISSVH
                     GLRASPYKVAYVAAKHGLEGLSKVAALEGAAHGVTSNCVNPGYVRTPLVERQIADQAEA
                     HGISPERVVTEVLLADAAVKRLVEPEEVAEAVAYLCGPHTSFVTGASLTMDGGWTAH"
     gene            complement(18907..19386)
                     /locus_tag="HUT19_RS06240"
                     /old_locus_tag="HUT19_06240"
     CDS             complement(18907..19386)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017949275.1"
                     /locus_tag="HUT19_RS06240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06240"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_176179489.1"
                     /transl_table=11
                     /translation="MAIPDFIRDLRATAGPQLLYLPGVSAVVFDDEGRVLLGRRADNGR
                     WVIICGIPEPGEQPAEAAVREVEEETAVRCVPERIVLVRTLDPVTYPNGDRCQFVDVCF
                     RCRAVGGEARVNDDESLEVGWFALDALPEMEDFSLTRIKQALVDGATWFEPVAAG"
     gene            19588..20610
                     /locus_tag="HUT19_RS06245"
                     /old_locus_tag="HUT19_06245"
     CDS             19588..20610
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018520996.1"
                     /locus_tag="HUT19_RS06245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06245"
                     /product="O-antigen ligase"
                     /protein_id="WP_176179490.1"
                     /sec_met_domain="Wzy_C (E-value: 2.8e-06, bitscore: 26.3,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASSVVGPVVQGQERPARGSTLDIAGAVVLGGCAVWALIASVGRT
                     ARPEGVLLAVLAVAAGYACGRIAGSLLPVAATTAAALAGFGLACTALEDLPGQEGVDAA
                     QWTLATGAACCAAWAARPLLLRSALWLLALAIAVTAAVGGGTAGGAASAAVLLCSFTAA
                     RLRRRLLGLAGLALLTAVAVGGCWAVAANAVPGGLPPALRAQLTEHRVRLWQDATRIAG
                     DNPVRGAGPDRFTELSPTAMEAPDPRTTPHSAPLQQAAGEGVPGVALLGAAFGWMLYAL
                     WRSPRSTPVVLTAAVALTALAIEASLGNALSFPQVTAGAGLLAGLATASRPDHAPAPLP
                     "
     gene            complement(20627..21187)
                     /locus_tag="HUT19_RS06250"
                     /old_locus_tag="HUT19_06250"
     CDS             complement(20627..21187)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014181875.1"
                     /locus_tag="HUT19_RS06250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUT19_06250"
                     /product="hypothetical protein"
                     /protein_id="WP_176179491.1"
                     /transl_table=11
                     /translation="MRHHHQQGKQTPAGEPPAVWTGRAHNRVQWVLAAAGAACLALGID
                     LAVASPWGSGIAPLLMSVIGCVAAGLLMLFGTIAFVHVAVRIDAETLEIRCGHLGLPRR
                     RIPLSDVVDVDVASRVTPCQWGGWGYRWRPEKGTAVVVRRGEGLVVRLGDGRVFTVTVD
                     DAEAAVWVIRQRLRLIAKPASQV"
     misc_feature    21498..21512
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.68"
                     /tool="antismash"
ORIGIN
        1 gccgcccttg atgacgagtt cgggcttggt tccgaaccag gccgggtgcc acagcacgag
       61 atcggcgagg cgtccgggct gggcggtgcc cacttcgtgg gcgaggccat gggcgatcgc
      121 cggattgagg gtgatcttgg cgaggtagcg cagcacccgc tcgttcgcgg ggcgctccac
      181 tccgccctcc cccgcgcgca gcgcctggac gtgggcgagc tgccaggtac gccgcacggt
      241 ctcggcaatg cggcccatgc ccatcgagtc cgagttgacg atgctgatgg cgccgaggtc
      301 gtgcagggcg ttctcggcgg cgatggcgtg gccgcggatg cggccgcggg agatctcgac
      361 atcgctgtgg acgtgatggt tctgccggtg cacggtcatc gtcatcggga acagctcgcc
      421 gacggtgttc gccgtatacg ggacggtggg ggtggtcgag gacggcagga tgttcggctc
      481 ggagaggacc tccagcagat cggggtgtcc gccgccgcct tccacgtggt acgcgtgcac
      541 ggtgcggccg cgggtggcgc cgatggtgtc gcgcagatat cccgattcgt tcatcgagtc
      601 ggtgtgcagt gcgacgggca gatcggcgtg ttcggcggtg gccaggcagg tgtcgatgat
      661 gcgcggggtg gccccgaagt cctcatggat cttgaagccg ccggccccgg cgagcaccga
      721 ctcgtccagc agggcgcggg agctggagga gccacggccg aggaaggcca cattgagcgg
      781 ggtgccgcgc caggaactca tcagagtgtg cagattgtgg gccgggttgc agccgatgtc
      841 ccagaccccg cccagcccca tgcccaccac cgtggtcaca ccggaggcga gcgcggcggg
      901 cgcgacctcg ggcgaggaca gatgcacatg gctgtcgacg atgccggggg tggcgatcag
      961 cccctccccc gtgaccaccg cggtgtgcga gtcgatggcg aagtccaccg gcatcaggtc
     1021 cgggttgccc actccgccga ccgcgacgat ccggccgtcc ttgacaccga tgtcggtctt
     1081 gcggacgccc agcaccgggt ccatcagcag cacactggaa accaccaaat ccagggccga
     1141 ggcccggtcg gaacgcgggg aggccagcag cccgtcgcgg acggtcttgc cgcagccgcc
     1201 cagcagttcg tcgccagggg tgccgtcgtc ggcctccacc tccacccaca gacaggtgtc
     1261 gcccaggcgg acacggtcac cggtggtggg gccgtagagg gcgttgtacg tgcatcggtc
     1321 gatccgcgtc atgccgactc ctccggttca tctccgtcgt ggcgggcggc caccaggtcc
     1381 acctcacgtt cggtccccgg ctcgaaggcc agggcagttc ccgccgcgac gtccagccgc
     1441 atcccggcgg cggcctcccg gtccagttcg agggcggaat tggcctccgc gagcgggtag
     1501 tgcgaggaga ggtagacggt gcggtcgccg ttgttgcgga tcgtcagccg cagccggggc
     1561 cgcccggcgt tgatcagcac cggctccgcg gccgtacgga ccgccccggg ggcgtggtcc
     1621 gccgcgccac ccacgatcgg gttctccacc gcgaccaggg acgttccgct cgggaacagc
     1681 gcttcgacct ggaccgtgcc gacgagggcg ggcactccct ccagcacatc gtccacggtc
     1741 agcagcgacc gcccggcctc gatcacctcg tccaggctcg ccccgtccca ggccgcctcc
     1801 agcacctcgt cgcagatgag ggcgatggcc tccggggcgt tcagccgccg gccgcgcgca
     1861 cggcggcggc gggccagttc ggcgacggtg aagagctgga cccgttccag ctcgcgaggg
     1921 gtcagatgca ctgcgtgacc tcctgggcgg tagaccccgg tgcgtgtcgc ccgggagttc
     1981 catcagaatc ccggggcgat ggaatccagc caaggttgaa atgcatccca tacgctgacc
     2041 agaatcgtgc acatgcacaa tgcggccgtt gccttccctc cgcccgaccc acgcatcgcc
     2101 gagctcgccc gggagtgcct ggacgacctc gacgggctga tcgagctgtg gatcgacgtg
     2161 gtgggccccg tccgccggac ctacgccgac cgcgtgccgg acgcggactt ccgggactcc
     2221 gcgcgcgacg ccctggagat gctgctgcgc accgtggccg agctagccgt gcccgagcac
     2281 atcgccgagg tgtccgaacg ggtcggcacc cggcgtgccc ggcagggggt accgctggag
     2341 tccctgctgg acgcggcccg gctggacttc cgggtggtgt ggacggccct ggtgcggcgg
     2401 gccgaggacc ggaacatgac acatctggtg gcctccgcgt actacgtctg ggaggcggtc
     2461 gagcgccatg tcaccggcat catgaccgct taccagcgca ccgtgctgga gatggggcgg
     2521 cgggccgagg acgagcgcca gatgtggttc gcccggctga tggactgcga cggccgcaat
     2581 ccgaccgtgg tgggtgacac cgcgctggcg ctcggcttcc aggtcagcgg ggagtacgtg
     2641 tgcgccgctg ccgccccgca gtacggcgcc gcactgcgcc gggccgcggc ggacctgcgc
     2701 accgcgggga tcccggtcca gcagcaggct ctcgattcgg cggtggtcct caccgcccag
     2761 ctcgggccgc gcaccaccgc cgacaccatc ctgggacatc tgggggagac gccctgcggg
     2821 gtgtcatccg ccgccgaccg cctggccgac gtaccgcgcg caatccggct ggccatcacc
     2881 acggcgcgca gccttcccat ggacgcccgc gggccgaggt ggctgcggga cagctggctg
     2941 gacgtcctgg tccaccacac ctcggatctc gcacacgacc tcgccgacga cgtgctcggc
     3001 ggactcggcc gaccggacat caccgacgcc gagaaggacc ggctgctgcg caccgttcac
     3061 gtccatctca ccgggaacgg tgcgatagcc gacacagccg cggccgtcta ctgccaccgc
     3121 aacaccgtgc agcaccgctt caaccgcttc cgcgagctca ccggtcacga cgtacgccgc
     3181 cccgaggacg cggccctcat cgccctggcc ctgcgggcca gggagcggcg cgcccggaca
     3241 gaggcgaccg gctgagccga gcggccctgc ctcatacacc gtccggaacg agcggcggtg
     3301 tgctctcggg acggcggcgg tgccgcatgg cctgccccag ggcgcagccc aggaggaaca
     3361 gcgacgcttc gtcccagggg cggtgtcaca cctaccaggc gtcctccctc accaggctgc
     3421 cgccccagcg cgaaccaacg atgatctcga tgcccaccat ccttcttgtg tgccaaccaa
     3481 acatcctcgt cacacggggt cagcggcgta cgcgcggcat gccgagaccg atccaggaga
     3541 tgatctcccg ctgcacctcg ttgttgccgc cgccgaaggt gaagaccacg ctgctgcggt
     3601 agccgcgttc cagttcgccg tggagcacgg cgcccgccgc accctccttg agcgggcccg
     3661 ccgcgccgac gatctccatc agccaggcgt aggcgtcgcg gcgcgcctcg gagccgtaca
     3721 ccttgacggc ggaggcgtcc tgcggggtca gggtctcgcg ctggagggcg tccaccatct
     3781 gccagttgag cagcttcatg gcgtccagcc gggcatgggt acgcgccagc cgggcgcgga
     3841 cccagccgag gtcgatcacc cggcggccgt cggcgagttt ggtgtcggcg gcccaccgct
     3901 ggacgccgcg cagggcgcgg atggccatgg tgccgtgagc ggcgagggtg acgcgttcgt
     3961 agttgagctg ggttgtgatc atccgccagc cctcgttctc ctcgccgacc cggcggtcgg
     4021 ccggcacccg gatgttctcg tagtagctgg cggtggtgtc gtgggaggcg agggtggtga
     4081 tgggggtgca ggagtagccg gggtcgtcgg tcggcaccag caggatgctg atgcccttgt
     4141 ggggtttggc ctcggggtcg gtgcggaccg cgagccagac ccagtcggcg gtgtcgccgt
     4201 tggtggtcca ggtcttctgg ccgttgacga cgtagtggtc gccgtcgcgc accgcgcggg
     4261 tcttcagcga ggcgaggtcg gttccggcgt cgggctcgct gtagccgatc gcgaagtcga
     4321 tctcaccgga gaggatcttc ggaaggaagt acgccttctg ttcctcggtg ccgtagcgca
     4381 tcagcgtggg cccgacggtg ttgagcgcca tgagcggcag cggtaccccg gcctgggccg
     4441 cctcgtcgaa gaagatgaac tgttcgaccg ggccgaggcc gcggccgccg tactcctggg
     4501 gccagccgac gcccagccag cggtcggcgc ccagccgccg gatggtctcg cggtagaacc
     4561 gcttctgccc ggcggggtcg ccgtagcggg cgtaggcgtt gtcggggacc agttcggtga
     4621 agtaggtccg cagttcggcg cgcaaccgcc gctgggcagg ggtgaattcg aggtccacgg
     4681 cccctcctgg agtctcacgt gcgccgcgcc ggcggcctgg gagcgtcctg ggatcgaggg
     4741 gcacggtaga acgtgttcca ccaatacgga aggggccgag tcacggagat cctacagtcc
     4801 gtcagttcgc cgttctcggc cgggcgttcg gccgccggcc gaccgtcggc cagggccggg
     4861 caccttgtcg tgttatggct tggcccagtt cacatctgac gctggatcca atctcacctc
     4921 attcgtgaag ttcccggtgg tcaaggtcag tcccgctcca tgccgggcgg cacactcgca
     4981 tcgctcggca cggtctcgta ccgcggcgga ctctcctcgc gcggcgggcc gttcgtgggc
     5041 gccgggccat ccgtggacga cgtgccatcc gtggacgaca gcccctccgt gggcgccggg
     5101 ccgccgtcgc ccggcggggt ctcgacccgc ggcgggccgt cgtcgccgcc ccgccgcaga
     5161 atccgcaccg gctcccccgg acgccaggtg cgcagcacca gttcggagcc ctccacggag
     5221 gtgtgcacca cctcggacac ctcggcgcgg aagagatgga agggctccgg cggccggacc
     5281 gcctccgcgt aacgggcgat cacctcgggg tcggtcacct cgaccgcccg cccgctgacg
     5341 cgtacatcgc cgtcgaccgg cccggcctcc ggaccggggt tggcctggac cgagaaccgc
     5401 ggatcgcggc gcagatccag cgccttgcgc gactccgaca tcatgccgag ccacaactcg
     5461 ccgtcacgga agtccacttc gaacggggtc agccgcgggg cgccgtcctg gcgcagggtg
     5521 gccagcacat ggtggcggta ccgcccgaag cggtcctccg cggcggtggc gaatccgggc
     5581 tcggccgcct ggaatccgga ccagctggtg gtggggttca tcgtcattcc gcccatggtt
     5641 ccgggcttac ccgacgtctc ctgtccggat ttccgggcct ccatctcccg cgcctgctcg
     5701 accggcagat gggcgttcca ctcggtgccg cgcagcggat aggcgatcca gtcgcgggcg
     5761 taggacggcg ggcggccgtg tccgcgcttg acgagcagcg cggtgggttc acgtccggcc
     5821 cggcgcagca gcgcggaggt actgagggac ttgttgttgc cactggtctg ggcggaggag
     5881 cagcccgcgt ggtaggcgat gggcagcgca cggtcgccga tcaccaggca gggcggccgc
     5941 agtcccatgc gggccagggc gtcggccgcc gtgcggtagc gcccgttgac ggtgtcggac
     6001 tggcccgcgg catggctgag gacggcgtac tggctggcga cttggagagc gacaacaacg
     6061 ccgagcgcga cggccatgtg ccggggcgac ttcgcgatgc gcaccgcgcg gaacaccagc
     6121 ccggcgatgg gcagcgcgag cagggcgtag gtgggcatca ggaagcgcgg ggcggagtag
     6181 tcgatgagca gcagataggg cagggcgagc gcgcccgcgc agatgacggg cagcagggtc
     6241 gtcggcagtc ccggggcgcg gcggggctcg ggccgcccca ggccgacgcg gacgcgggtg
     6301 cgccgccggt ggcggtcgcg cagcgcggcg accagggcga cggcggtgag cagcggcagc
     6361 gcgagccacc acacggtcag ctccgggtgg cgcagcggca cttcgcaggg tcggcacagc
     6421 tggggtccgt tcaggctgcg cagggcggcg ccgacggcga agtggaggcc catcccgccc
     6481 tcgacatcgc tggagacgtc aagccgctgg gtgatgccgc cgaagcggtc gtacgcctca
     6541 ccgatccact gcgcggcgcc gagcagcaga ccgccgacca cggccggcag ggcgggccgc
     6601 caggtgcgga cggcgatggc cgcgacgagc agcggcagtc cgagccagcc gccgtccggg
     6661 gtgcggacga gggtgacgcc cgcgaggacg gccgccagcc accagcgggc gttgcggtcg
     6721 gcggggacac gcaggaacca cccgacggtg gccacggcgc ccagcgccac ccacaggttc
     6781 ggcatcaccg cgggcccgct gatcatcgtg atccacagtc cggagaagag cagcgcggcc
     6841 agcgcgaccg tggtccgggg cagcagccgg gtccagaccc ggaaggaggt gtacagcgcg
     6901 agggcggaaa gcaccgtcag gagtacccgg agcaccggaa tggaggaggt cgcggcgacg
     6961 atgggggcga cgagcaggct gatgccgcgc gagcgggggg cactgaagaa cgcggccgga
     7021 ttgcgcgggt ccacctggga gacgtacacg gactcgtccc agcccagcgc gtgcccggtg
     7081 tgcgggatga ccacggcgag ctggaccacg gcgtaggcca gtgccaccag accgagccag
     7141 ggcgcggggc gccggtaccg cggcggctca gacgagtgcg ggcgtgggcg cgcggctgcg
     7201 gccgccggtg cggcagtatt ctccatgcgc gcaccatatg atgcctatgt acctttttcg
     7261 gcctattagg ccgttcggct caacgtccaa ggggtgccat gtcagcgccg gatccgtagg
     7321 ctgtttgagc ggtgaacagc ccccacccgg cggaggacgg acacagccat gaaaatgctc
     7381 atcaacgtcg ccgaatccgt ggtcgcggac gccctgcgcg gaatggccgc ctcccatccc
     7441 gagctgacgg tggacgtcga gaaccgcgtg atcgtccggc gggacgcacc ggtcgcggac
     7501 aaggtggccc tggtctcggg tggcggatcg ggacacgagc cgctgcacgg cggtttcgtg
     7561 gggcgcggca tgctcgacgc ggcgtgtccc ggggaggtct tcacctcgcc cgtgcccgac
     7621 cagatggtgc gcgccgccac cgcggtggac agcggcaagg gcgtgctgtt catcgtgaag
     7681 aactacaccg gtgacgtcct caacttcgac atggccgccg agctcgccga ggacgagggc
     7741 gtccaggtgg ccaaggtcct ggtcaacgat gacgtggcgg tgaccgacag cctctacacg
     7801 gcgggccgcc gcggcaccgg cgccaccctg ttcgtggaga agatcgcggg tgccgccgcc
     7861 gaggagggca tgccgctgga gcgggtggag gccgtcgccc gccgggtcaa cgagctctcc
     7921 cgcagcttcg gggtggcact gagcgcctgc tccacccccg gcaagggcgg ccccaccttc
     7981 gacctcccgc ccggggagct ggagttgggc gtgggcatcc acggcgagcc ggggcgcgag
     8041 cgcagggcca tgatgacctc ccgcgagatc gccgactacg cggtgaacgc ggtactcgac
     8101 gacctgcccc cggacaatcc ggtgctggtg ctggtcaacg gaatgggggc gaccccgcat
     8161 ctggagctgt acggcttcgc cgccgaggtg caccgggtgc tcggcgagcg ccggatcgcg
     8221 gtggcacgta cgctcgtcgg caactacgtc acctcactcg acatggcggg cgcctcggtc
     8281 acgctctgcc aggtcgatga ggaactgctg cggctgtggg acgcacccgt acggaccgcc
     8341 gggctgcggt ggggctgctg acaggccggc cgacgcccgt acgtacgctg tcgccgttcg
     8401 ctatcgaccg aggaggcgtc tgtgtccagc agtgaacccg ccgtcgaaca cgtgctcgac
     8461 acccctttct tccaccgctg gctctccgcc gcggccgcgt ccgtgacccg tgacgcggcc
     8521 cggctcaccg agctggactc cgcgatcggc gacgccgacc acggcaccaa tatgcagcgc
     8581 ggcttcgccg cggtgaccga ggcgctggac aaggagcggc cgggctcccc cggggccacc
     8641 ctcatcctgg ccggacgcca gctgatctcc aaggtcggcg gcgcctccgg gccgctctac
     8701 ggcacactgc tgcgccgggc gggcaaggcg ctcggcgacg ccgaggagat caccccgcag
     8761 cagctgacgg acgccctgcg ggccggggcg gacgcggtgg cacagctcgg cggtgccgcg
     8821 cccggtgaca agaccatgct ggacgcgctc cttcccgcgg tcgaggcgct ggccgcgggc
     8881 ggctcgttcg cggcggcggc cgaggccgcc gagaagggcg cgctggccac cacaccgatg
     8941 ctggcccgca agggccgggc cagctatctg ggtgagcgca gcatcggcca ccaggatccg
     9001 ggtgccgcct cgtcggcgct gatcgtcgcg gccctcacgg aggccgcccg atgagcgagg
     9061 aaacccagga gaagctggtc ggcatagtgc tggtctcgca cagcgccgcg gtcgccgagt
     9121 ccatagcgga gatggcggcc ggactggcgg gcggcgtcga cgcgccggtg cgcgccgccg
     9181 ggggcaaccc ggacggcggg ctgggcacca gcccggagcg gatcatcgag gcggcccgtg
     9241 cggtggacca gggcgcgggg gtggcggtcc tggtcgacct gggcagtgcg gtactggccg
     9301 tgaagtcact gctggcggag ggcgacgaac tgcccgacgg cgcacagctg gtggacgcgc
     9361 cgctggtgga gggcgcggtc gcggcggtgg tcaccgcctc caccggagcg gatgtggacg
     9421 cggtcgcgca ggcggcctcg gaggcgtacg actaccgcaa ggtctgaacc cggggcaccc
     9481 ccgggtgggt acgcgacacc acccgggggc gccgcccggc gcacagccga aactcggtcc
     9541 gcccttcaac aaaaacagcg cgcttttgtg cgctggtctc ttttctccac tcccccacat
     9601 acccggggac ttatccccgc tttgacttca acgtgccatc acccgacaga acagtcttcc
     9661 gattctgtcg aagatgtgac tagaatgcgc acgtccgagt gggcagattg gcgcaactca
     9721 aggggaattc atgggcgcat atcagtggtc cccctcatcg cgcgtggaat tgtcccgacc
     9781 acggtggacc atctgtttcg tcatgcgcct gacctgcggc cacgagcagc acacgatatc
     9841 ccggtcgatg atcgtccgcc ctgcgcggcg catcccgtaa cagggcccgg catcgaccgt
     9901 ccggcgatcc gccattcgca cgattccgtg gcttctgcat gtctgttttt ccctgtctca
     9961 ctcaaccgat ttcgcattca gacgtggagg agccggtctc atgaccacac ccacgctcag
    10021 cccggacttc ttggataccg acgccatccg cggcgcggtg gagcgcgttc tcgacgactt
    10081 tctgaccgcc aagtcccgca gccccgcacc tcccccactc ccctcgctcc ccagactgct
    10141 cggggatttc ctggcgggcg gaaaacgcat gcggccgctg ctgtgcgtca ccggctggcg
    10201 agccgtcggc ggcgccggcg acccgggtcc cgtgttacgc gtggcggccg gtctggagat
    10261 gttccacgcc ttcgcgctcc tccacgacga cgtcatggac gacagcccgg tccgccgcgg
    10321 ccgtccggcg atgcaccgca ccctggccgc gctgggcgcc gcccatctga gccaggagcg
    10381 gatcgagcgg tccggggtca acggcgcggt gctgctcggc gatctcgccc tgctgtggtc
    10441 ggacgagatc ctgcacaccg cgggcctcac cccggtgcag ctggccgccg tcctgtcacc
    10501 gctctccacc atgcgcaccg aggtgatgct cggtcagttc ctcgatctgc gggccaccgg
    10561 cacactcacc gacgacgtcg aggccaccct caccgtcaac cgctacaaga ccgccaccta
    10621 caccgtggag cgcccgctgc acatcggggc cgccgtcgcg ggcgccgggc ccggggccat
    10681 ggacgccctc acccgctacg cgctgccgct cggcgaggcg ttccagctcc gggacgacct
    10741 catcggggtg tacggcacag aagagtcgac cggcaaatcc ccgctggacg atctgcgcgc
    10801 gggcaagaac accaccctga ccgccctggc gctgcgcgcc tccgaccgcg tccaggacgc
    10861 ccaactgcgc gaactgctcg gcgatccgct gctggacgag aaacaggccg ccatcgtccg
    10921 ggagatcttc gacgccaccg gcgcccggga gaccgtggag cggatgatcg aggaccgcgg
    10981 gcgacaggcc ctgcgcgccc tggacgacgc tccgttcacc cccgacgcgg tcacggcgct
    11041 gcgccggctg gtccggatgg ccacggtgag gacatcatga ccgccgacct cttcgaggcc
    11101 ggccccacgg acctcggtac acccagcctg cgcccgtacc gggaggagtg cacccgccgg
    11161 ttcgccgagc tgttcgcccg ccacatcggg caccggccgg tcccccggac cctgaccccc
    11221 gaggagctgc gcgaggtcat cgccgcgtgc aacgcggccg tggcgcccct cggcaccacg
    11281 gtctccgacg agcgctggat ctcctatctg gaggtggtgt gctggtccca gagcgcccgt
    11341 cacatacggg acatggaggc gttcaaggcc gtctgcgtcc tcaactgcgt gacgttcgtc
    11401 tgggacgaca tggatcccgc cctgcacgac ttcgaactct tcctgccccg gctgcgcggg
    11461 atctgcgaga gctactacgc cgaggaggac gcctggttcg cgtacgaggc cgcccgtgcc
    11521 ttcgtcacca gcgaccacat gttccgtgac tccccgctca aggcggcgct gtgccgcacc
    11581 tcgccggagc agtacttccg cttccgggtc acggacgtcg gcgtcgactt ctggatgaag
    11641 atgtcctatc ccgtctaccg gcaccgggag ttcaccgaac acgccaaaac gggtctggcc
    11701 gcccggatga ccacccgtgg cctcgccgtc gtcaacgact tctactccta cgaccgcgaa
    11761 gtctccctgg ggcagatcac caactgcttc cggctgtgcg atgtctccga cgaggcggtc
    11821 ttcaaggagt tcttccagga ccggctggac gacatcaccg aggacatccg ctgcatcacg
    11881 gcgttcgacg aggtcagccg ggacatcctg ctggacctgg tctacggcaa cttcatctgg
    11941 accaccggca gcgagcgtta ccgcgcggcc gtgaaccacg tcaactcgcg catccggtag
    12001 agccccgcag aggaaggacg ctccgcatga ggaccgcgca gcacacggtc acccacggct
    12061 ggcaggttgc cgacgccccc ggcgggctcc cgctgatcgg ccacgccctg cgtctggccc
    12121 ggcggccgct gggcttcctg gcctccctgc ccgcccacgg cgatctggtg gaactccggc
    12181 tgggcccgca gcgcgtccat ctgccctgcc atccggaact ggtccagcag gtgctgctca
    12241 acgggcgcgt ctacgacagc ggcggtccgg tgaaggacaa ggcccggcag atcctcggca
    12301 acggcctgat caccgccggg cgggcggacc accgacggca gcggcggctg gtgcagcccg
    12361 ccttccacac cgcccggatc gagggctacg ccgaggtgat gcggcacgag tgcgaggcgg
    12421 tggccggatc gtggaccacc ggccgggcca tcgacgtcag ccgggagatg cagacgctca
    12481 ccacccggat caccgcccgc gcgctgttca ccaccgatat ggctccgcac gccgtggccg
    12541 aggtccagca ctgtctgcgg accgtcgtcc ggggcgcgta ccaccgggcg atcgacccca
    12601 ccggtctggt cgcccggctg ccgctcacgg ccaaccgcac cttcgagacg gcactgtccc
    12661 ggctccaccg gcggatcgac cggctgatcg ccgactaccg ggccaccggg ggcgaccgcg
    12721 gagatctgct ctccgcgctg ttcgccgccc gggacgaggg gactggggag cggctgtcgg
    12781 agcgggaggt ccacgaccag gtgctgaccc tgctgctggc cgggatcgag accaccgccg
    12841 ccgccctgac ctggacctgg ttcctgctgg gccggaaccc ggcggcccag gccgcgctgc
    12901 acgccgaggt cgacgcggtg gtgggcgaac ggaccccggg ctacgccgat gtgccccggc
    12961 tcgcctacac ccagcgggtg ttcaccgagg cgctccggct gttcccgccc gcgtggatca
    13021 tcacccggac caccaccgag cccacggagc tggccgggcg gcggctgccc cggggggccg
    13081 atgtgctgat cagcccgtac atgctgcacc gcgacgccag gctgttcccc cggccggagt
    13141 ccttcgaccc cgaccgctgg ctgccggagc gggccaagga cgtggcccgc ggctcctatc
    13201 tgccgttcgg ggccgggagc cggaagtgcg tcggggatgt cttcggcatg acggaggcga
    13261 ccctcgcgct ggccgccgtc gcccgccgct ggcggctgcg gcccgtgccc ggcacccgac
    13321 tccgcccccg gccgcagatg agcctcaccg ccggaccgct ggcgatggtt ccggagccgc
    13381 gctgaggacc ggctgacgac tcctcacggg ccgcggcggc accccgccgt ggcccggttc
    13441 ccgcggtctc cttctccgac cgcgggaacc gggggcagtt ccccattccc gcgaatttca
    13501 aacatgaacc ggagagaatt ccccgtttag tgttagggtc ttcgctcatg ggcgaccgtg
    13561 tgaacaaggc gactccgctg cgccgggatg cgcagcgcaa tcgcgaaatg ctgatcgcag
    13621 cggcccggga gatctacgcc gaccagggcg tggacgcacc gctcgatgac atagcccggc
    13681 gtgccggagt cggcagcgcc accctctacc gccggttcgc cggccgggcc gagctcatcg
    13741 aagccgtctt cggtgagtcc ctcaaggaca ttctgcgggc ctcgctggag gcccgccaga
    13801 gcatcgacgc ctggggcggg ctcaccacct acctcgagcg catcttcacc ctgctcgtca
    13861 ccgaccgggg caccaacgac ctgatgacca ccgccatcca gggcgtcccc tcgctcgaca
    13921 gcctccggac ggaacaccgc aagaccatcg acgtcctgct gcggcgggct cagaaggagg
    13981 gggcggtccg ggacgacgtc accgccgagg acttcctctt cctcaccgtc atgctgggcc
    14041 ggacggtgcc gggtgcggcg gtcgcggccc cctacgcctg gcgtcgctat ctggccatgc
    14101 tcctcgacgg gctgcgcccc gaggcggccg ggccgctccc ggcccccgcg ctcaccccgg
    14161 accagttcgc caccgccgtc gcccacctgg gcagaccccg ccgcccccgc cagggccgca
    14221 ccgagcacta gtccggcgga tcgtagcggg cccgtgtcat ggacgccggg cgcataccgg
    14281 ggcggcgaac tgtggtgtcc caccacatac gccactgacc tgcgccttcc tacggtatgg
    14341 cgacacatca acgtccccgc cgaccgttac ggaagtggtg tccatggccg cgcccgctcc
    14401 gccagccccc gcccgtctgc ggcgtatcgt cgccgccagt ctcatcggca ccaccatcga
    14461 gtggtacgac ttcttcctct acgggtcggc cgccgcgctc gtcttcaaca agctcttctt
    14521 cccggactcc gatccgctcg tcggcaccct gctgtcgttc ctgacgtacg cggtcggctt
    14581 cgccgcgcgg ccggtgggcg cgctggtctt cggacactac ggggaccggc tcgggcggaa
    14641 gaagctgctg atcctgagtc tgctgctgat gggcggggcc acctgcgcca tcgggctgct
    14701 gccgacgcac gccacggtcg gctcggccgc gccggtgctg ctgaccgcgc tgcggctggt
    14761 ccaggggttc gcgctcggcg gtgagtgggg cggggcggtg ctgctggtgt cggagcacgg
    14821 ggacgcgcgg cggcgcgggt tctgggcgtc ctggccgcag accggcgcgc ccgccgggca
    14881 gttgctggcc accggagtgc tctccgcgct gaccgcgctg ctgtcggacg ccgcgttcga
    14941 gtcctggggc tggcgggtgc cgttcctgct gtcgggtgtg ctggtgctgg tcggcttgtg
    15001 gattcgtctc tctgtcgatg aatcgccggt cttccaggcg gcactggccc aggccgaggc
    15061 ccgcaaggcg gaggccggac ggcagccgga cgcggccgag aagctgccgc tggtcgccgt
    15121 cctgcgccac cactggcggg atgtgctgat cgccatgggc gcccggatgg ccgagaacat
    15181 cagctactac gtgatcaccg cgttcgtcct cgtctacgcc acctccgacc atgtggacct
    15241 gggcaaacag accgcgctca acgccgtact gatcgcctcc gccgtgcact tcgcggtgat
    15301 cccggcgtgg ggcgcgctgt cggaccggat cgggcggcgc ccggtgtatc tgctgggggc
    15361 ggcgggcgtg ggcgcctggg ccttcccgtt cttccacctc atcgacaccc ggggcttcgg
    15421 ggcgctgctg ctcgcggtga ccgtcggact ggtcttccac ggggcgatgt acgcgccgca
    15481 ggcggcgttc ttctccgaga tgttcgcgac ccggatgcgc tactcggggg cgtcgatcgg
    15541 ggcacagttc tcgtcggtcg cggccggtgc gcccgccccg ctcatcgcca ccgcgctgct
    15601 ggccgactac gacagcgcca cccccatcgc gctgtacgtc atcgcggcgg cgctgatcac
    15661 cctggtggcg gtgggcgcgg cgcaggagac ccgggaccgc gatctgaccc ggatcgagcc
    15721 gagcgcgccc ggcggggagc gggccacggg gacgctggac gcggcggaga gtacaccccg
    15781 ttcggcctcg gcgtcgtagg gcaggcgcaa ggcagccgtc aggcaggtgt acggaggcgg
    15841 gtcccggacg cgtccggggc ccgcgtccgt acgccggtgg tgtgccgcgg ccgacggcgg
    15901 cggtcagcgg gccgaggcca gccggtgcag ccgcagcgcg agctggatct ccagggcgcg
    15961 ggacggcgac tgccagtcgg ggccgagcag ccgcccgacc cgctccagcc gctgggcgac
    16021 ggtgttgacg tggacgtgga gttcgtcctt ggtacgggcc gggctcatcc cgctcgcgta
    16081 gtacgcgtcc agggtgcgca ccaggtcggt gccgcggcgt gtgtcgtagt cgaggaccgc
    16141 gccgatggtg cggtggacga agtcctggac ccgggcgccg tccgggacgc cgtcgcgggt
    16201 ggcacccagc agcagcccca gaaagccgaa gtcctcggcg gccgcgccct gtccggaccg
    16261 gccgagcacc cgcagcgcgg ccagacagcg ccgcgcctcg gcgtagccgg aggcgacctc
    16321 gccgggccgg acggcgggct cggggaccgg cgaggaggcg ccgacggtga ccggtgcgcg
    16381 cagcgcggtg cccagctggc gggcggtccg ccgggccagg gcgtcggcgg tgtcgccctc
    16441 ggccagcggc agcagcagca cggtgccgcc gtcacgggcg gcggccagac cctgcccggt
    16501 ggcggccaga tgggaggcgg cggaccacag gcgctgccgg tcggcggcct cctcggcggg
    16561 cgcgccaccg cccggatccg caccagaggc accggacgca ccgcgtgcac cggccgcacc
    16621 agccgtggcg ggcgcgtcga gccccgcggc gagcaccaca tggggcgcgt ccaggtccgc
    16681 ccgcagccgg gcggcgcgct cgcgcagcag ccgtggttcg cggtcggggg cgtcgaggag
    16741 gtcgtccagc agttcgccgc gcacccgctg ttcggcctcg cccgccgagc gccgggcgag
    16801 ctggagcagc gaggtgacca ccgcggcccg ttccagggtg cgctggtcca ccgggtcaag
    16861 gccggggtgg ccgtgcagca ccagcgcgcc gagcagttga ccccccgcgg agacggcggc
    16921 gatccagtcc tccccgtgcc ggaccgcgtg gccgtcggcc cgcgagcggt ccacggcggc
    16981 cgccggcgcc ccgccggcct cgacgaactc caccgaaccg ctgagcactt cggccaccgc
    17041 ggtggcgacg tcgtgcaccc cgccgccgcg cagcaccagg gcggtcagcc ggtcgtggac
    17101 gtcggaggcg cgctcgatga ccgcgctgcg gtcccggatg atctcgttgg cggcctccag
    17161 ttcggccagc gcggaacgcg tctcggcgag caggttggcc gtgtcgatcg ccacggccgc
    17221 gtgggcggcg aacgaggcga gcagcgcgat ctgctcccgt tcgaagaccc gggcccggcg
    17281 gtcggcggcg aacagcaccc cgatgacccc gctgccgagc agcagcggca ccccgaggat
    17341 ggccaccaga ccctcgtccc ggacgctcgc gtcgatggtg tgggtgtgct ggaagcgggc
    17401 gtcgtcgaag tagctgtcgg tcacataggg gcgtgcggtc tgggccacca gcccgccgag
    17461 cccctccccc atgccgagcc gcagctgctg gaagcgggcc gagaccgaac cgtcggtgac
    17521 ccgcatatag gtgtcaccgg cgctcgggtc gtggagcgtc agataggcca cctcggtgcc
    17581 cagcagtgac cgggcgcgct ggacgatggc ctggagcacc gcgtccaggt cgcgcagccc
    17641 ggcgaggtcg tgcgcggtct cgaagagcgc ggacagctcg gcctcgcgcc gccgccgtcc
    17701 ctccagctca ccccggacgc ggagggcgag cagcttggcg cgctccaggg ccgccagccg
    17761 gtcggccggg gccttgtcgg cgcgggcgcg cagacccggg cgctcgtacg cctcggcggg
    17821 cgcgccgcgc gccagcagtt ccaggtacgg ggtctccggc ggatcgtcgg ccatggtcac
    17881 agggatactc ccgccgggtg cggcggcgcc acccgtcgga cgtgcgggag cgcgctccgg
    17941 cggcccgacg gggagcctgc cggacgcggg ccctccgggc ggatgtccgc tcagtgggcg
    18001 gtccatccgc cgtccatggt gagcgaggcg ccggtgacga aggaggtgtg cggaccgcac
    18061 agataggcga cggcctcggc gacctcctcc ggttcgacga gccgcttgac cgccgcgtcg
    18121 gcgagcagca cctcggtgac gacccgctcc ggggagatcc cgtgggcctc ggcctggtcg
    18181 gcgatctgcc gctcgacgag tggggtgcgc acatagccgg ggttgacgca gttggaagtc
    18241 accccgtggg ccgcgccctc cagggcggcc accttggaca gcccctcgag cccgtgtttg
    18301 gcggccacat aagccacctt gtacggggag gcgcgcaggc cgtgcaccga ggagatgttg
    18361 acgatccggc cccagccctg cccgtacata tgcggcagcg cgccccgcac cagccggaac
    18421 ggggcctcca gcatcaccgt gagcacccgg gagaagacct cgggcgggaa gtcctcgatg
    18481 gggcggacga gctggagtcc ggcgttgttg accaggatgt cggtgcccgc ggcggcctgc
    18541 tcggcggcgt cgaggtcggt caggtccagg gcccgcgcct cgacggtgcc cggcccggcg
    18601 ggggccttgg ccaccagccg ggccagcccc tcggcgtcga ggtcgacggc gcgtaccgtg
    18661 gcgcccgcgg cggccagccg gagggtgcac gcccggccga tgcccccggc ggcgccggtg
    18721 accagggcgg tgcggccggt cagatcgagg gcggcggcac ccggggccgg gccggagacg
    18781 ggggcgggag ctgagggggt cgcgggagct gagggggtgg cggcgctcat gagcggcaga
    18841 ttaggcggcg ggtgtgcccg caccgatgtg gccgggacac acacttcggc gcccggtggt
    18901 gggcggtcac cccgcggcga cgggctcgaa ccaagtcgct ccgtcgacca gcgcctgctt
    18961 gatccgggtc agcgagaagt cctccatctc gggcagcgcg tcgagcgcga accagccgac
    19021 ctccagcgac tcgtcgtcgt tcacccgcgc ctcgccgccc accgcccggc agcggaagca
    19081 gacgtcgacg aactggcacc ggtcgccgtt gggataggtc accgggtcca gggtgcggac
    19141 gaggacgatc cgctcgggca cacagcgcac cgcggtctcc tcctccacct cgcgcaccgc
    19201 ggcctcggcg ggctgttcgc cgggctcggg gataccgcag atgatcaccc agcggccgtt
    19261 gtcggcgcgg cggcccagca gcacccggcc ctcgtcgtcg aagacgaccg cgctcacacc
    19321 cggcaggtac agcaactggg ggcccgcggt ggcccggagg tcacggatga agtcggggat
    19381 cgccatgcgg tgagggtacc gggcggatca cggcggcctc cccggcggtc acgccctggc
    19441 acaccgtgtc cgtttcacca cggacacatg gtttctgcgc accatgtaca catacctcag
    19501 cacaagcgct accgttcccg gtggcatggc ccgcacccgg tctccggccg tggtcgcggt
    19561 gccgtcacga cgggggggtc gacggaaatg gcgtcatcag tggtgggacc ggtcgtgcag
    19621 gggcaggaga gacccgcccg cgggagcaca ctcgacatcg cgggcgcggt ggtcctgggc
    19681 ggctgcgcgg tctgggccct catcgcgtcg gtgggacgca cggcccgccc cgagggggtg
    19741 ctgctcgccg tgctggcggt ggccgccggg tacgcctgcg gccggatcgc cggatcgctg
    19801 ctgccggtcg ccgcgacgac ggccgccgcg ctcgcggggt tcggtctggc ctgcaccgcg
    19861 ctggaggacc tgcccggcca ggagggcgtg gacgccgcgc agtggaccct ggccaccggc
    19921 gcggcctgct gtgcggcctg ggcggcgcgg ccgcttctcc tccggtccgc cctgtggctg
    19981 ctggccctgg cgatcgcggt cacggccgcg gtgggcggcg gcacggcggg cggggcggcg
    20041 agcgccgccg tactgctgtg ctcgttcacc gccgcccggc tgcggcggcg gctgctgggc
    20101 ctggcgggtc tggcgctgct caccgcggtc gccgtcgggg gctgctgggc ggtggcggcg
    20161 aacgccgtcc cgggcggact gccgcccgcg ctgcgcgcgc agctgaccga gcaccgggtc
    20221 cggctgtggc aggacgccac ccggatcgcc ggggacaatc cggtgcgcgg ggcgggcccg
    20281 gaccgcttca ccgagctgag ccccaccgcc atggaggcac cggatccgcg gaccacaccg
    20341 cactcggccc cgttgcagca ggccgcgggc gagggagtgc cgggggtggc gctgctgggc
    20401 gcggccttcg gctggatgct ctacgcactg tggcgctcgc cccggtccac cccggtcgtc
    20461 ctgacggccg cggtggcgct gacggctctg gccatcgagg cgtccttggg caacgcgctg
    20521 agctttccgc aggtgacggc gggtgcgggg ctgctcgcgg gcctggccac ggccagccgt
    20581 ccggaccacg ccccggcgcc gcttccctga gcggccggag cgccggtcag acctgtgagg
    20641 cgggcttcgc gatcagccgc agccgctggc ggatcaccca caccgccgcc tccgcgtcgt
    20701 ccaccgtgac ggtgaagacg cgcccgtcac cgaggcggac caccaggccc tcaccgcgcc
    20761 gcaccaccac cgccgtaccc ttctcgggcc gccaccggta gccccagccg ccccactggc
    20821 agggggtgac ccgggaggcg acgtcgacgt cgaccacatc gctcagcgga atgcggcggc
    20881 gcggcagccc caggtggcca cagcggatct ccagggtctc cgcgtcgatc cggaccgcca
    20941 cgtggacgaa ggcgatggtg ccgaagagca tcagcagtcc ggcggcgaca cagccgatga
    21001 ccgacatcag cagcggggcg ataccggagc cccaggggga cgcgacagcc aggtcgatac
    21061 cgagcgccag acacgcggcg cccgcggccg ccagcaccca ctgcacacga ttgtgcgccc
    21121 gcccggtcca gaccgcgggc ggctccccgg ccggggtctg cttcccctgc tggtggtggt
    21181 gcctcatagt tggcagggta ctcacgttcc gctaccgcgg caccagatca caccgtttcc
    21241 gccggtggag gtgggtttcg gtcagccgcg gacggtgctg acgggcgcca gcagagtgcc
    21301 ctcggcgtac gccagcgcgg ccggcggcag ctcctcctcg cgaccgctga ggaggaccgt
    21361 gagcccgccg cgcgccggga cggtccggtc ggtcggcagc ggatcgacgc cgatccggcg
    21421 cagcgcctgg gcggcgacgg ccccggcgga tccgaggagg acgagggagg gggcgcccgg
    21481 ctgctgcacg gcggtccgga tacggtcggc gaccaactcg tagtgggtgc agccgaggac
    21541 gacggtcgtc acatcgcgcg gggtgcgctc ggcggcgacg gccaccgccg cgtcgatggc
    21601 ggcgaagtcg gcgtactgga cggcgtccgc gagccccggg caggccaccg gcgtcacctc
    21661 gaccccggcc gcgaactcgc ggatcaggtt cccctggtac gggctgccgg tggtggcggg
    21721 ggtggcccag atggcgaccg gaccgccccc ggcggcagcg ggcttgatcg cgggcaccgt
    21781 gccgatgacc ggcagcgcgg gctccagttc ggcccgcagc gccggaatcg cgtggacggt
    21841 ggcggtgttg caggcgacga tcagcacatc ggggcggtgc gccgcggccg cgcgggcgca
    21901 ggccagcgca tgctcggtga cgtcctcggg agtacgcggc ccccacggca tgccgtcggg
    21961 gtcggaggag agcacaagat ccgcgtcggg ccgcagacgg
//
