LOCUS       NZ_JABWGO010000014     22667 bp    DNA     linear   CON 29-SEP-2024
DEFINITION  Nonomuraea rhodomycinica strain TBRC6557
            NODE_14_length_223130_cov_28.6101, whole genome shotgun sequence.
ACCESSION   NZ_JABWGO010000014
VERSION     NZ_JABWGO010000014.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nonomuraea rhodomycinica
  ORGANISM  Nonomuraea rhodomycinica
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 223130)
  AUTHORS   Chanama,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2020) Microbiology, Mahidol University, Faculty of
            Public Health, 420/1 Ratchawithi Road, Ratchathewi, Bangkok 10400,
            Thailand
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 26-MAY-2020
            Assembly Method                   :: SPAdes v. 3.10.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013363995.1-RS_2024_09_29
            Annotation Date                   :: 09/29/2024 04:09:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,940
            CDSs (total)                      :: 8,866
            Genes (coding)                    :: 8,758
            CDSs (with protein)               :: 8,758
            Genes (RNA)                       :: 74
            rRNAs                             :: 4, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 12 of 108
            Pseudo Genes (incomplete)         :: 99 of 108
            Pseudo Genes (internal stop)      :: 6 of 108
            Pseudo Genes (multiple problems)  :: 8 of 108
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:20:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 62775
            Orig. end                         :: 85442
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABWGO010000014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22667
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22667
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22667
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12667](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12667
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            502..939
                     /locus_tag="HT134_RS48215"
                     /old_locus_tag="HT134_38895"
     CDS             502..939
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016430.5"
                     /locus_tag="HT134_RS48215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38895"
                     /product="sigma factor"
                     /protein_id="WP_217708874.1"
                     /transl_table=11
                     /translation="MNVEDGRIIERSLSEPEAFAEIFDRHFRTIHRYLARRLGTDAADD
                     LAGEVFTLAFARRTTYRIDQPVALPWLYGIAGNLIHAHQRARRRDATLIGSLPPESTPP
                     PSRTRWSPPSTRAAGCVGSGRRSATCPRRTRRRCSSTHGRT"
     gene            <825..>1079
                     /locus_tag="HT134_RS44990"
                     /pseudo=""
     CDS             825..>1079
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /locus_tag="HT134_RS44990"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="RNA polymerase sigma factor"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVESTVDARRRMRRIREAISDLSEADQTTLFLYAWEDLSYQEVAA
                     ALDVPVGTVRSRLYRIRRLLREPLRASQAIEELGRVIRTI"
     gene            complement(1488..1781)
                     /locus_tag="HT134_RS38925"
                     /old_locus_tag="HT134_38900"
     CDS             complement(1488..1781)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891307.1"
                     /locus_tag="HT134_RS38925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38900"
                     /product="DUF1330 domain-containing protein"
                     /protein_id="WP_175605507.1"
                     /transl_table=11
                     /translation="MAKGYWVSVYPAISDPESLTAYNKLARPAVQAGGGRVLSRGGRVV
                     AHEAGITQRVVLIEFDSFEQAVAAYESEEYQKALVALPDGFERDFRIVEGID"
     gene            1940..2842
                     /locus_tag="HT134_RS38930"
                     /old_locus_tag="HT134_38905"
     CDS             1940..2842
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890292.1"
                     /locus_tag="HT134_RS38930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38905"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_175605508.1"
                     /transl_table=11
                     /translation="MAPDTVSLRYFLVLAQELNFTRAAARIGIAQPALSARMRRLEAEL
                     GTALLVRNTRSVVLTTAGAALAESAPPALAALDRAWDTARSAAAGELGTLRIGYSLSTG
                     AETVPALVDRLIRANSGLQVGAVPMATPEISPAVADGRIDAGITRGEQPGSGVRRYLLR
                     RQRVGVQLAQHHPLAEHPEIEIADAAAYPLRLPDRAANPVIHDQLSALFRDIRPHPRFH
                     TPAVSFDMSQRDLRDGVTLAPAGEAAVTASPAGLTWRPLRGAPSLTIHLVLPREQSPLH
                     RRVRAVAKALAHELHWLPD"
     gene            3127..3561
                     /locus_tag="HT134_RS38935"
                     /old_locus_tag="HT134_38910"
     CDS             3127..3561
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024854.5"
                     /locus_tag="HT134_RS38935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38910"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_217708875.1"
                     /transl_table=11
                     /translation="MKSESVSLNRSALLALQRATHATLHLISTELVDLDLTASEINALA
                     NLADGHGRTVSQLGAAVGARPTTLTSVLDRLERRGHITRGTRAGDRRSVLIELTDSGRA
                     AAAVIAQTLTDIENRALEGLPAEAVAGFYAVLDALIKEGS"
     gene            3558..4178
                     /locus_tag="HT134_RS44995"
     CDS             3558..4178
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS44995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_217708876.1"
                     /transl_table=11
                     /translation="MTTHDHGPYSGQAAHVNRPLKTLTGSEERRRRHPHAGQGVNGTDE
                     ESSPFTELMGEVMATAERFGHRQHVQLTWLAVRRYGTTAAVDLISDGIQRTARYAGAPQ
                     KYNATVSRAWVELVGHHAGQSNTDDFDAFADHNPALLDKRLLARFYRSSTLASGPARTG
                     WVEPDLAPFDETGLKSRACLPPNRACMGISAVWFRRPSSVMEK"
     gene            complement(4229..4519)
                     /locus_tag="HT134_RS38945"
                     /old_locus_tag="HT134_38920"
     CDS             complement(4229..4519)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015925.5"
                     /locus_tag="HT134_RS38945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38920"
                     /product="putative quinol monooxygenase"
                     /protein_id="WP_175605509.1"
                     /transl_table=11
                     /translation="MSLFVIAEFLAAPGQHDRLRTALEALIEPTLDEPGCLAYQAYVDP
                     NDPASMVIVERWENRQAFDEHFTTPHLRHAQQVLDRILARPLTLRTLVEAP"
     gene            complement(4533..5591)
                     /locus_tag="HT134_RS38950"
                     /old_locus_tag="HT134_38925"
     CDS             complement(4533..5591)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017597792.1"
                     /locus_tag="HT134_RS38950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38925"
                     /product="aldo/keto reductase"
                     /protein_id="WP_312888754.1"
                     /transl_table=11
                     /translation="MTSSQLPVHRLGRTDMEITRLGFGSWAVSGSGWTFSWGATDDTES
                     VAAIRHAVDSGVNWIDTAAVYGLGHSEELVGKAVADLPEADRPYLFTKVGLVWDPDDPS
                     AAPRRIMKPASVRREIEDSLRRLGADRIDLYQVHYPDTGESLEYAGGGFGAVSPNATPL
                     EEYWQVMADLKAEGKVRAIGLSNHTPDLLEVAERIAHVDVIQPPFSAINRSSAAEIAWA
                     RAHETGVIVYSPLQSGLLTGAFSAERVAGLPADDWRTAHHDFTAGLTANLRLAEALRPI
                     AECHGRTVAEVAIAWVLAWPGITGAIVGARTAAQVDGWIGAGSLELTPADLEEIATAIT
                     VSGAGSGPARHA"
     gene            5760..6626
                     /locus_tag="HT134_RS38955"
                     /old_locus_tag="HT134_38930"
     CDS             5760..6626
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152525.1"
                     /locus_tag="HT134_RS38955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38930"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_175605510.1"
                     /transl_table=11
                     /translation="MMWDRRAELGEFLRSRRARLRPEELGLTAYGQRRRVPGLRREELA
                     QLAGVSVDHYIRLEQGRTLHFSAEVLDAVARALRLDPAERAHLHRLARPAPPVPPGVPA
                     TADRPPLRAGIHRMLASIHDVPAYLVDRDTTVLAWNRPAAALITDFGALPPEQRNMARL
                     TFLDEGIRHLYADWPTRARDIVAFLRLDAGHELADASVAALVAELSAASDEFRRLWSEH
                     RVKDKRHGRYLYRHPLVGELELAYEVLRLPDHPGLALVVHTAEEGSASETALRLLTTWA
                     GQETPAP"
     gene            complement(6861..7355)
                     /locus_tag="HT134_RS38960"
                     /old_locus_tag="HT134_38935"
     CDS             complement(6861..7355)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012514.5"
                     /locus_tag="HT134_RS38960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38935"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_175605511.1"
                     /transl_table=11
                     /translation="MGELVERVDEQDRVLEVVERAEAVRRRWMHRIATTICRDPMGRIL
                     VLRRAEGHVRFPGHYDVMVGGAVGVGESYEAGAARELVEELGAGVPVRFLFKFLCRDGI
                     SPVWFGVHEALIAEPLAADPSEIAWHAWLTDLELRKVVDRGPFVPGGREALRRYLGRPA
                     H"
     gene            complement(7411..7626)
                     /locus_tag="HT134_RS38965"
                     /old_locus_tag="HT134_38940"
     CDS             complement(7411..7626)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS38965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HT134_38940"
                     /product="hypothetical protein"
                     /protein_id="WP_175605512.1"
                     /transl_table=11
                     /translation="MPVEALERFESPADDGSGGEQPATDIDRMDGETDITDQEGSDRPM
                     ASGRSVSFGGADPKRGSFRRRLESAG"
     gene            complement(7776..9338)
                     /locus_tag="HT134_RS38970"
                     /old_locus_tag="HT134_38945"
     CDS             complement(7776..9338)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013508.5"
                     /locus_tag="HT134_RS38970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38945"
                     /product="CARDB domain-containing protein"
                     /protein_id="WP_217708877.1"
                     /transl_table=11
                     /translation="MRHIRGMCYPVATLAAVALPLTLFGAVPADAAPAVTAPAVLRVAP
                     DPASCPDQVSLVNGGFEQPVVSRGGWALFPDASQPGAPNHVPGWLTSATDHMIELWASP
                     PNPTNTPPKEGRQLAELNANQVSTLYQDRATTPGTKLYWRLSHRGRLGVDTMAVDIGAP
                     AAPVQQQVMSDGTGSWGTYSGTYIVPAGQTTTRFAFRSVSAAGGNRAIGNLLDDISFAT
                     APCVVLSKTASPRGPVDVGDVITYRLTAVNKGGATAENVRLSDTVPAGTTFVPGSLRVV
                     DGPGSGDKTDQAGDDQGAFDAASGKVSFTLGNGATPAAGGSLPNATSLPGGTTVEFKVK
                     VGRDAAGGGKVTNRGTLSYENRLGPEPERLTSTSGDVVTEVNPAVDLSVVKSADATRVT
                     VGQTVIYRVTVRNAGPSDATGVTVKDVLPSNLAFVSATASDGTYAPASGIWRVGSLACG
                     ASATLTVYAKATAIGETTNTATADGKELDLDPANDSDSVKICVDPEPFCPYCVKGPGQA
                     PKN"
     gene            9736..9861
                     /locus_tag="HT134_RS47360"
     CDS             9736..9861
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS47360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_281387873.1"
                     /transl_table=11
                     /translation="MDELPQVAGPVASSVPAATTDAFALAEPFNGRNKKAQKCDR"
     misc_feature    9946..9960
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.08"
                     /tool="antismash"
     gene            10001..12667
                     /gene="lanL"
                     /locus_tag="HT134_RS38975"
                     /old_locus_tag="HT134_38950"
     CDS             10001..12667
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="HT134_RS38975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38950"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_246366364.1"
                     /sec_met_domain="Pkinase (E-value: 1.3e-17, bitscore: 57.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.3e-42, bitscore:
                     138.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSEDPAILRDIVAAEIGRAGARDWSVAEEDFWCKVTPDAYPMPD
                     QGWKLHVSATMLSAPLALARVSRVLTEARCAFKFPARLSDYWKLLEPHCSRAQAGKFIT
                     VYPLDDAESVRLAALLDDATRGLPGPVILSDRPYRKGGIVHYRYGAFSGHRVLGNDGFY
                     EIRLRSPQGLLVPDERRPSFSPPPFATCPFEVPAASPRPRAAAVMLNDRFIVREAVRHA
                     NRGGVYLAEDTTTGHDVVVKEGRPHACADLSGRDARDRIAAERSCLEDLATTGITPAVV
                     DFFEQGGHTFLVEEFVPGITLQRWSDENAGPLGEDGFGSAAAQVLPVVSRLTAVLKALH
                     GRGYVFGDLSPNNVMLSPGGELRLIDLEHAAVPGTTVMVGGTPGYLAPELAGHTGEFRP
                     APHPSADLYSLGAIVYFLAVGAHLDPPGPDQAARVAAVAAANPTLALLRPLVEGLLATE
                     PERRWSLDRCLRFLTETELAPERATPRHGTRPPRRIGRLIDDGIAHLVETMDTSEDAPS
                     PWPNAADGIEADPCSVNGGAAGVLGVLARAEPHAPATAELARWLRRRLAAEDVWPPGLH
                     FGRSGAVWALYDAATAMGDAELARFAVRAARRLPTGHPSSDVTHGLAGCGMTLLHIALA
                     SGDLALRDRAAETFRNLHQARSYGAGRPQWPTPQTFDSGLAGANHFGFAHGIAGIGTAL
                     LHAGRALHQPDWTATVHEIARALYEHAEVDSDTAWWPTQRGDLSTVRPRRPYWCSGSSG
                     IGSFLVRYWRATGDPPALDLARKAAAAVHRTRWQSGPVPCHGLPGDGEFLLDMADLTGD
                     DRYQRWARDLAGCLEIRAADRRGRLLVPGPHGDFPPTFLAGTAGIVAFLLRLRDRSARL
                     WMPEEAPRLAVPAAGRR"
     gene            12980..14761
                     /locus_tag="HT134_RS38980"
                     /old_locus_tag="HT134_38955"
     CDS             12980..14761
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="HT134_RS38980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38955"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_175605514.1"
                     /transl_table=11
                     /translation="MHDRPLVASEKAPATGTWRRVVRLFMPHRLAICFVVLLVVAYSAL
                     NAAVPLLTQLVFDRALFGAGGPDLPLLALIAGLAAATACAVGVVDLGQTWVSARVAQQV
                     VHALRVELFGRLQRMPLAFFAATRGGEIQSRLANDTAQIEHAVKDTLPGTLSGVIGFVA
                     AAGAMVALSPRLAGAALVLAPIVVWVASRSGRALKNVSEVSQRSRAHLSSIVAERLCLG
                     AVTLARVHGRSADEAGRFAAESRRLIRLGVRSGLVAQGVLSAGHVFFVLTPYLVFVAAG
                     LSDGITPGTLVAFTVLQARLYQPLWQLLHVSTEFRSAQGAFERVFDYLDMEPAPELEPG
                     PDPRPAPSPGPGALTVREATFRYAAEDRDRPALDGVSLTLAAGSTTLVVGPSGSGKTTL
                     GHLLAGLHAPTEGSVRVDGAEIGRPSPGRVCIATQEPFLFQGSIADNLRYAAPDATADD
                     LVRACRLAHVHERIMALSDGYDSLVGERGALLSGGERQRIALARALLADASVLVLDEAT
                     SALDPMTELEVVKAILAERAGRTTVMITHRFGVLDSFDTVVALDEGRVAEHGARLDLLG
                     DRHGWYARTVRAQTGAA"
     gene            complement(14847..15431)
                     /locus_tag="HT134_RS38985"
                     /old_locus_tag="HT134_38960"
     CDS             complement(14847..15431)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS38985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HT134_38960"
                     /product="hypothetical protein"
                     /protein_id="WP_175605515.1"
                     /transl_table=11
                     /translation="MPKPSRLLSTGVAAAALLATMAMSVTSPASAAQPANGRETVVTEL
                     DYNSTGWRYRQVPPATDVPLFYERGFDDSEWQTGQAGFGTASGCSFNTPENVKTSWARN
                     TDILVRHWLHLPRNAQQVRIQGTIDNDAQVYLNGHLVQSVRSGYCRTGAIDVVVPAEYL
                     ECCNLLAIRGHDYGGSTYLNVRVTYVKPPQV"
     gene            complement(15651..17255)
                     /locus_tag="HT134_RS38990"
                     /old_locus_tag="HT134_38965"
     CDS             complement(15651..17255)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011292304.1"
                     /locus_tag="HT134_RS38990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38965"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_175605516.1"
                     /transl_table=11
                     /translation="MITVRDVALRAGARLLLSDISFTVSPGDRIGLIGRNGVGKTTLMT
                     ALAGLAKPAAGTISRTGAVEFLAQDSRAADPAVTVTDRILSARGLDRALRRLRAAEAAM
                     AAATGPAALERAMNAYARAEAAFQTGGGYAAEAEAARVAAGLGLPDRVLSRPVGNLSGG
                     QRRRVELARILFAGHGGTLLLDEPTNHLDADSIAWLRTFLRGHQGGLVLISHDTGLVAE
                     VVNRVFHLDATRAAIDIHNTGWDAYLTQREADRRRRERQRANAERKAATLHAQADRMKA
                     RSATAVMARSMARRADRMLAELEPARRTEKVARIRLPEPAPCGRIPLGAVSLAKSYDGR
                     QVLDGVDLAVDRGSRLVVLGLNGAGKTTLLRILAGEELPDAGRVVRGHGLRLGYFAQEH
                     DTLRPDRTVRQNLTDAAPHLTDGEARQVLGAFLFSGDDVDKPAGVLSGGEKTRLALAGL
                     VHSGANVLLLDEPTNNLDPVSRDEVLAAVGSYPGAIVMVTHDQGAIDALRPDRVLLLPD
                     ADEDLWSEDYRDLVALA"
     misc_feature    complement(17238..17252)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.14"
                     /tool="antismash"
     gene            complement(17348..17485)
                     /locus_tag="HT134_RS38995"
                     /old_locus_tag="HT134_38970"
     CDS             complement(17348..17485)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS38995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HT134_38970"
                     /product="hypothetical protein"
                     /protein_id="WP_175605517.1"
                     /transl_table=11
                     /translation="MLDESPDAPTRENPRLDVGSLPVPVDLATAARPRTGIRSGAHRVG
                     "
     gene            complement(17515..18453)
                     /locus_tag="HT134_RS39000"
                     /old_locus_tag="HT134_38975"
     CDS             complement(17515..18453)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) SubclassB1"
                     /gene_kind="resistance"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009082472.1"
                     /locus_tag="HT134_RS39000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38975"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_175605518.1"
                     /transl_table=11
                     /translation="MCPADLTPNPSPDLSDLPDVRTSPPPIVRGGPVELADGVYVIPDN
                     RVELVPNVGIVVGEHAALVIDTGMGPRNGAHVLEQARRLAGDRHLYLTLTHFHPEHGFG
                     AQAFKGAATIVYNASQRAELHRKGAAYVEMFKGLSAAAAAELEGVELVDPDLVYEGRAE
                     LDLGGRKAELRAVGPAHTGSDQVIVIDDRVLFGGDLIETRIFPIAPYFPPYDVDVDGAA
                     WIGVLDELAAREPEIVVPGHGEVAGVSLIRDVRDYLGYVYGEASRLRAAGVSADETAAR
                     IDEQARARWSTWERPEWIGFAARAFYAGAHR"
     gene            18529..19200
                     /locus_tag="HT134_RS39005"
                     /old_locus_tag="HT134_38980"
     CDS             18529..19200
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024701.5"
                     /locus_tag="HT134_RS39005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38980"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_175605519.1"
                     /transl_table=11
                     /translation="MAKGRYHHGDLRSALLDAAEALVRERGTDGWSLREASARVGVSPS
                     AAYHHFASRDTLVRALSERTLAWLGERLRQDCEHASGQGDDPQRRLIALGRSYVSWSLD
                     DPAVARLVLRGGATAPDSAISPHPHDVLTAELDRLADAGALPEPAREGAEFVLWAALHG
                     LAVLLADGLVRFDDPRAVELQTERVVRTTLNGLAQEASHAAGRPAGRSAHTERLARRSR
                     G"
     gene            19465..19878
                     /locus_tag="HT134_RS39010"
                     /old_locus_tag="HT134_38985"
     CDS             19465..19878
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR02246.1"
                     /locus_tag="HT134_RS39010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38985"
                     /product="SgcJ/EcaC family oxidoreductase"
                     /protein_id="WP_175605520.1"
                     /transl_table=11
                     /translation="MSNSRAADEAAIQAVLVDSYKAWEAGDADGMVANYTADATAIMTG
                     SLRDSREVIRQSMALAFEGPLKGSSTYNKQLGIRFVGRDGAIVISESAILFPGETEVAD
                     EARKVNCTWVFEKRDGQWLIAAYHNSPVLAPAL"
     misc_feature    complement(19468..19483)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            20013..21116
                     /locus_tag="HT134_RS39015"
                     /old_locus_tag="HT134_38990"
     CDS             20013..21116
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018656194.1"
                     /locus_tag="HT134_RS39015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_38990"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_246366337.1"
                     /transl_table=11
                     /translation="MPWQAVDDRAGRAIRPLRMLTAVAGYGDCGCSGDGGRRVMTGQEG
                     FDRRIEPFRTELLAYCYRMLGSAHDAEDLVQDTYLRAWRAREQYDDTRSSLRTWLYRIA
                     TNACLTALEVHGRRPLPSGLVAASDPLGPLVQGEHVPWLQPLPDSLLDAGDPAGAVMDR
                     SSLRLAFAAALQHLSARQRGALILRDVLSFSAAETAEILGTTVVSVNSSLQRARTRVKE
                     VGVRQERVSEPPAAEQRAWVERYMRAFELADVEGLKRLLTEDVIMEMPPMLNWFAGRDN
                     YGLFMEWVFGAAGKDWLLKEVAANGGQPGFAAYQRVGDGYSLHTLQIFTVTDEGISRNS
                     VFQDPDIYATFGLAAKLDDQGLAIAEA"
     gene            complement(21393..21626)
                     /locus_tag="HT134_RS39020"
                     /old_locus_tag="HT134_38995"
     CDS             complement(21393..21626)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS39020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HT134_38995"
                     /product="hypothetical protein"
                     /protein_id="WP_175605521.1"
                     /transl_table=11
                     /translation="MSTGWGTAYNRHRRWSLDGTWARILDGLRAGCDEAEGEDWTVSAD
                     STVVRAHQHAARARRAPALDIPSKGPMKITNG"
     gene            complement(21696..22298)
                     /locus_tag="HT134_RS39025"
                     /old_locus_tag="HT134_39000"
     CDS             complement(21696..22298)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.5"
                     /locus_tag="HT134_RS39025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_39000"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_175605522.1"
                     /transl_table=11
                     /translation="MLAETVATAIEIALRFSRRRAVHRLDREGDTVVVNKIILRAAVPG
                     EADALTALTRRSKAYWGYPQAMLDRMAEMLSISSAAIRDGRVVVAERDCALAGYYQISG
                     EPPHGELADLFLEPEVIGTGLGRTLWEHAVESARSAGFHTLTIESDPHAEAFYLRMGAE
                     RVGEREVAPGRSLPILRATVDSKRPFPRRPVDQGDSC"
     misc_feature    22592..22606
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
ORIGIN
        1 catttgttca ggccagcggc ttgatctcat tcgactctca gtgtgttgcg tcatcctctc
       61 gacgtcaata gattcctaat atcgacccat cctttcagca tgaatcataa atatgaggct
      121 ctcggcgggt ccgcgccacg agcaggccgc gccgtgtgcg cctcaccgat caggccggcg
      181 gacaggtcat ctctctcgcg gggaggtcct gggagacgac cggcccgcgc cgcagaaggc
      241 aatgaccgac accttcaccg cccgtgctcg ccccgcgaag tcgccggccc cgccgaactc
      301 gccttcaccg tgcagatccg gtgtgaccgg tctcggcgtc acgggcgaac tcgcggacca
      361 ggcgcatctc cccgggtcgt gagctgcccc gcgtgatgtg ctgagccgtg cgacggatcc
      421 gaccggtcgc cacgcagtcg tgaaccgcga tgcccgggaa cgacaaagac gaggcgtgac
      481 cttgttgcac ctggaacagc catgaacgtc gaagatggcc gcatcatcga gcggtcactg
      541 agcgagccgg aggcgttcgc cgagatcttc gaccgtcatt tccgcaccat ccatcgctac
      601 ctcgcgcgac gcctgggaac cgacgccgcg gacgacctcg ccggtgaggt gttcaccctg
      661 gctttcgcgc gccgcaccac gtatcgcatc gatcagccgg tcgcgttgcc gtggctgtac
      721 gggatagcgg gcaacctgat tcacgcgcat cagcgcgcgc gacgacgcga cgcgacgctg
      781 atcgggagcc tcccgccgga gtccaccccc ccgccttcga ggacgcggtg gagtccaccg
      841 tcgacgcgcg ccgccggatg cgtcggatcc gggaggcgat cagcgacctg tccgaggcgg
      901 accagacgac gctgttcctc tacgcatggg aggacctgag ctatcaggag gtggcagcgg
      961 ccctggacgt ccctgtcggc acagtccgct cccggttgta ccggatacga cgcctcttgc
     1021 gtgaaccgct gcgcgcgagc caggccatcg aagaactcgg gcgcgtcatc aggaccatct
     1081 tcatctgcgg ctacctcgcc gacgaggcac tccggcagga gatggcagga gatccacgag
     1141 ggactgaacg tggtcgagaa ccggaactcg gcgaacaagg acctcttcta cggcaaggcc
     1201 ggcgacctga ccggcgacga ccccaagctg cgcgcccgcc tcacccccga ggacctgcgc
     1261 ggcctttccg ctctcttctg gagccgcctc cacctgtacg gccgcgtggt cacggcgccg
     1321 ggaggggggc cggtgccgct ggtgtggctg ccccgaagct gccaggtcgt ggccaagctc
     1381 ccgacgcgca acggcaacac gagcacccac gaaccccgcc acaccagcag ccgcaccagc
     1441 gaaaaccaag acggtggatc tacagtgaag atccgactgc acctcggtca gtcgatgcct
     1501 tcgacgatgc ggaagtcgcg ctcgaagccg tcggggaggg cgaccagcgc cttctggtat
     1561 tcctcgctct cgtacgccgc gacggcctgt tcaaagctgt cgaactcgat cagaacgacg
     1621 cgttgcgtga ttccggcctc gtgggcgacg actcgaccgc cacgggacag gacgcgcccg
     1681 cccccagcct ggacagccgg acgggccagc ttgttgtagg cagtcaggct ctcagggtcg
     1741 gaaatggcgg ggtagacact gacccagtag cccttagcca tggaaacctc ctgtgttcgg
     1801 ccggacacgt ccgacttcga cgggtaccgc ggtccggtga atcgtcatat gcgcaggtta
     1861 gggcttgatg tgcggtcgag ggaaagaccg gtacgggata gcctcagaac ggatcgttat
     1921 caatcggcag ggagggcaca tggcgccgga tacggtgagc ctgcggtact tcctggtgct
     1981 ggcgcaggag ttgaacttca cccgcgcagc cgcacggatc ggtatcgcac agcccgcact
     2041 cagcgcccgg atgcgccgat tggaggcgga actcggtacg gccctgctgg tccgcaacac
     2101 gcgtagcgtc gtcttgacca cggccggtgc ggctttggcg gagtcagcgc cgcccgcgct
     2161 ggcggcgctg gaccgggcat gggacaccgc ccggagcgcg gcggccggtg aactgggcac
     2221 gctgcgcatc ggatacagcc tcagcaccgg agccgagacg gtaccagccc tggtggacag
     2281 gctgattcgc gccaacagcg gactccaggt cggcgcggtc ccgatggcga caccggagat
     2341 ctcccccgcg gtcgccgacg gccgcatcga tgccgggatc acccgcggtg aacagccggg
     2401 cagtggcgtg cgccggtacc tgctgcggcg tcagcgcgtc ggggtccagc tggcgcagca
     2461 ccatccgctg gccgaacacc ctgagatcga gatcgccgac gcggccgcgt atccgctgcg
     2521 actcccggac cgtgcggcca accccgtgat ccacgatcag ctgtccgcgc tgttccgaga
     2581 catccgacca cacccccgat tccacacgcc cgcggtctcg ttcgacatgt ctcagcgcga
     2641 cctgcgcgac ggggtcaccc tcgccccggc cggagaagcc gcggtcacgg catcaccggc
     2701 cggtctcacc tggcgaccgc tgcggggcgc gcccagcttg acgatccact tggtcctccc
     2761 acgcgagcag tcgccgctac accgccgcgt ccgtgccgtc gccaaagccc tggcgcacga
     2821 gctgcactgg ctgccggact gacgtccaag aggtcaagcg agacggacgc ctgcggtggc
     2881 gcggccgagt cggcgcagtt gagcgctctg ctggaggcat cggcgggcaa gtgctggtcg
     2941 catctggagc ggctacgaca cccgccgacg cggaccatgg gcgtcgggat ggctcggacg
     3001 tgggagcgcg tggaggagag ccccgcgttt gagttcgggc gggtgaagtt gggtgcacct
     3061 gccacacgaa ccgtctgtcg ccgctggctc gcccagacgt acaccgatat cgtactatcc
     3121 gaaatcgtga agtccgagtc cgtatcactg aaccggtccg cgctgctggc cttgcagcgc
     3181 gccacccacg ccaccttgca cctgatctcc actgaactcg tcgacctcga cctgaccgcc
     3241 tccgagatca acgcactggc caacctcgcc gacggtcatg gccgcaccgt ctcccagctg
     3301 ggggccgcgg tcggggcccg ccccacgacg ctgaccagcg tgctggaccg gctggaacgc
     3361 cgcggtcaca tcacccgcgg cacgcgcgcc ggcgaccgcc gctcggtgct catcgaactg
     3421 accgactccg ggcgcgcggc ggccgccgtc atcgcccaga ccctgaccga catcgagaac
     3481 cgcgcgctgg agggcctgcc cgccgaagcg gtcgccggct tctacgccgt tctggacgcg
     3541 ctgatcaagg aagggtcatg accacacacg accacggccc gtactccggc caagcggcac
     3601 acgtcaaccg gccgctcaag acgctgaccg gctcagagga gcgccgacga cggcatccgc
     3661 acgccggcca aggagtgaac ggcacagacg aggagtcctc gccgttcacc gagttgatgg
     3721 gggaggtgat ggcgactgcc gagcggttcg ggcaccgcca gcacgtccaa ctgacgtggc
     3781 tggccgtccg ccgctacggc accacagcgg cggtcgacct gatcagcgac ggcatccagc
     3841 gcaccgcccg ctacgcgggc gcaccacaga agtacaacgc caccgtcagc cgggcctggg
     3901 tcgaactggt gggccaccac gccggacagt cgaacaccga cgacttcgac gcgttcgccg
     3961 accataaccc cgcgttgctc gacaagaggc tgctcgcccg cttctatagg tcctcgacgc
     4021 tggcaagcgg cccggccagg accggctggg tcgagccgga cctcgctccg ttcgatgaga
     4081 cggggctcaa gtctcgtgcc tgtctgccgc cgaaccgcgc ctgcatgggg atttcggcag
     4141 tgtggttccg gcgaccgagt tcggtgatgg agaagtgagc cgaggacagc cggccgttcc
     4201 cgtgccgggg gaacggccgg cctggtccct agggcgcctc gaccaaggtg cgcagggtca
     4261 gtggtcgggc aagtatccgg tcaaggacct gctgggcgtg acgcaggtgc ggggtggtga
     4321 agtgttcgtc gaaggcctgc cggttctccc agcgttccac gatcaccatg gaggcagggt
     4381 cgttggggtc gacgtaggcc tggtaggcga ggcaaccggg ttcgtccagc gtcggctcga
     4441 tcagggcttc cagtgccgta cggagccggt catgctggcc gggcgcggcc aggaactcgg
     4501 cgatcacgaa aagggacatg atggggcctc cttcacgcgt gccgggccgg accgctgccc
     4561 gcgccggaca cggtgatcgc ggtggcgatc tcctcgaggt cggcgggagt cagttccagc
     4621 gagccggcac cgatccagcc atcgacctgg gcggccgtgc gtgcgcccac gatcgcgccg
     4681 gtgatgccgg gccaggccag cacccaggcg atggcgacct cggccacggt gcggccgtga
     4741 cactcggcga tcggccgcag cgcctcggcg agccggaggt tggcggtcag gccggcggtg
     4801 aagtcgtggt gggcggtgcg ccagtcgtcg gcgggcaggc cggccacccg ctcggcggag
     4861 aacgcaccgg tgagcagccc ggactgcagc ggcgagtaga cgatgacacc ggtctcgtgg
     4921 gcgcgggccc aggcgatctc ggcggcggac gaccggttga tcgccgagaa gggcggctgg
     4981 atgacatcga catgcgcgat ccgctcggcg acctccagca ggtctggcgt gtggttggac
     5041 agcccgatcg cccggacctt gccctcggcc ttcagatcgg ccatgacctg ccagtactcc
     5101 tccagcgggg tggcgttcgg cgacaccgct ccgaacccgc cgccggcgta ctccaacgac
     5161 tcgccggtgt cgggatagtg cacctggtac aggtcgatgc gatcggcacc cagccgccgc
     5221 agcgagtcct cgatctcccg gcggacgctg gccggcttca tgatccgccg gggcgcggcc
     5281 gacggatcgt ccgggtccca gaccaggccg accttggtga aaaggtacgg ccggtcggcc
     5341 tcgggcaggt cggcaacggc cttgccgacc agttcctccg aatggcccag accgtagacg
     5401 gcggcggtgt cgatccagtt gacgccggag tcgacggcgt ggcggatcgc ggcgaccgac
     5461 tcggtgtcgt cggtggcgcc ccagctgaag gtccagcccg agcccgacac ggcccacgag
     5521 ccgaagccca gcctggtgat ctccatatcg gtacgcccga gccggtgaac gggcaactgc
     5581 gaagacgtca cgtgcgtgaa cctccaaggt cttgccgcca cggtgtgccc gaggtggcgc
     5641 cggagtcgtt ccggcgccac ctactgtggg cgggcggccg cggctcagcc aggggcggcg
     5701 cgtgcctggg cacgccatga ccaggcacgc tcaggcgcgg gtccgcgata ctggtgcgca
     5761 tgatgtggga tcggcgtgcc gagctgggcg agttccttcg gtcacggcgg gcgcggctgc
     5821 gtccggaaga gctcggcctg accgcgtacg ggcaacggcg ccgtgtcccc gggctgcggc
     5881 gcgaggagct ggcgcagctg gcaggggtca gcgtcgacca ctacatccgg ctggaacagg
     5941 gacgcacctt gcacttctcc gccgaagtgc tggacgcggt ggcccgggcg ctgcggctgg
     6001 accccgccga acgcgcgcac ctgcatcgcc tggcccggcc cgctcccccc gttccgcccg
     6061 gcgtgcccgc cactgccgac cggccgccgc tgcgcgccgg catccaccgg atgctggcat
     6121 cgatccacga cgtgccggcc tacctggtcg accgcgacac caccgtcctg gcctggaacc
     6181 ggcccgccgc cgcgctgatc accgacttcg gggcgctgcc gcccgagcag cgcaacatgg
     6241 cccggctgac cttcctggac gagggcatcc gccacctgta cgccgactgg ccgacacgag
     6301 cccgcgacat cgtcgccttc ctccgcctgg acgccgggca tgagctcgcc gatgcgtccg
     6361 tcgccgccct ggtcgcggag ttgtcggccg ccagcgacga gttccgccgg ttgtggagcg
     6421 agcaccgggt gaaggacaaa cgccatggac gctacctgta ccggcatccg ctggtcgggg
     6481 agctcgagct ggcctatgag gtcttgcggc tgccggatca cccggggctg gcactcgtcg
     6541 tccacaccgc cgaggaaggc tctgcctccg agaccgcgct ccggctcctg accacctggg
     6601 ccggtcagga gacacctgcc ccctgaccgc cactccccgg cgcggcggac gcgttccggc
     6661 caccggcgag gcacatcaac gctccgcccc tcacaagaag gggaccaagc cccgccgcac
     6721 gccccacctg atctgccgct caccctccgc tcgccaagtc ccatgtgccg cggggtgagg
     6781 cagcggcccg tggcggagct ggtcacgaat gcgttgaagc cgctgctcgt cccgtgactg
     6841 aggaagggag cggctgttcg tcaatgagct gggcggccaa gatatcggcg cagcgcttct
     6901 cgcccacctg gaacgaaggg ccctcgatcg accaccttcc gcagttcgag gtccgtgagc
     6961 caggcatgcc aagcgatctc ggacggatct gcagccaaag gctcggcgat caaggcctcg
     7021 tgcaccccga accagacagg gctgatcccg tcccggcaca ggaacttgaa caagaagcgg
     7081 accgggacgc cggcgcccag ttcctcgacc agttcgcggg ccgccccggc ctcatacgat
     7141 tcgcctacgc ccacggcgcc gccgaccatc acgtcatagt ggccgggaaa gcgcacatgc
     7201 ccctcggctc ggcgcaacac gaggatccgc cccatcggat cgcggcagat cgtcgtcgcg
     7261 atccgatgca tccaccgccg acgcaccgcc tctgcccgct ccacgacttc cagcacgcgg
     7321 tcctgttcat ccacccgctc gaccagctca cccatgcagc acacggtcgc agccgccacc
     7381 gacaacctgg ctgaggatca ccccactgcg ctatccggcg gactcgagac gccttctgaa
     7441 ggagccccgt ttcgggtcgg cgccaccaaa ggacacgctc cggccggatg ccatggggcg
     7501 gtctgacccc tcctggtcgg tgatgtcggt ctcgccgtcc atccggtcga tgtcggtggc
     7561 cggttgctcc ccacccgacc cgtcgtcggc cggcgactcg aagcgttcga gcgcctcgac
     7621 cggcaccttt ggctctctgc gccagtcgtg ggccagtggc tggacgggtc gccggcccac
     7681 gacggcgcgg ggcgccctgg gatcaacgat cgtcccagga cgcgatcggt gacagggccg
     7741 cgttccggtc ggatgcgtcg accggcgtcc cggcgctagt tcttcggggc ctgcccgggt
     7801 cccttgacgc agtacgggca gaagggttcg gggtcgacgc agatcttgac gctgtcggag
     7861 tcgttggcgg ggtcgaggtc cagctccttg ccgtcggccg tggccgtgtt ggtcgtctct
     7921 ccgatcgctg tggccttggc atagacggtc aacgtggccg aggcgccaca ggccagggaa
     7981 ccgaccctcc atatcccgct cgccggcgcg taggtcccgt cggaggccgt ggcggacacg
     8041 aaggcgaggt tggacggcag cacgtccttg accgtgaccc ccgtcgcgtc gctcgggccg
     8101 gcgttgcgta cggtgacgcg gtagatgacg gtctggccca cggtcaccct ggtcgcatcg
     8161 gcggacttga ccacgctgag gtccaccgcc gggttgacct cggtgacgac gtcaccgctg
     8221 gtggaggtca gtcgctccgg ctccgggccg agccggttct cgtagctgag tgtcccccgg
     8281 ttggtcacct tccccccgcc cgctgcgtcc cgaccgacct tgaccttgaa ctccacggtg
     8341 gtgccgccgg gcaggctcgt ggcgttgggc agcgagcccc cggccgcggg ggtggcgccg
     8401 ttccccaagg tgaaggagac cttgccggac gcggcgtcga acgcgccctg gtcgtcgccc
     8461 gcctgatcgg tcttgtcccc gctgcccggg ccgtcgacca cccggagcga gccgggcacg
     8521 aaggtggtcc ccgcagggac ggtgtcggag aggcgcacgt tctccgccgt ggcgccgccc
     8581 ttgttgaccg cggtgaggcg gtaggtgatc acgtcgccga cgtcgaccgg ccctcgcggg
     8641 ctcgcggtct tgctgaggac gacgcatggc gcggtcgcga aggagatgtc atcgagcagg
     8701 ttgccgatgg cgcggttccc tccggccgcc gagacggaac ggaaggcgaa cctggtggtc
     8761 gtctggcccg cgggcacgat gtaggtgccg gagtaggtgc cccagctccc ggtgccgtcc
     8821 gacatgacct gctgttgcac cggggccgcc ggggcgccga tgtccacggc catcgtgtcg
     8881 acccccagcc ggccgcggtg ggacagccgc cagtacagct tcgtccccgg ggtggtcgcg
     8941 cggtcctggt acagggtcga gacctggttg gcgttcagct cggcgagttg cctgccctcc
     9001 ttgggcgggg tgttggtcgg gttcggcggg ctggcccaca gctcgatcat gtggtcggtg
     9061 gcgctggtga gccagccggg cacgtggttc ggcgcgccgg gctgcgaggc gtcggggaac
     9121 aaggcccacc ccccgcggct gacgaccggc tgctcgaaac cgccgttgac cagcgacacc
     9181 tggtcggggc aggaggcggg atccggcgcg acccgcagaa ccgccggggc ggtgacggca
     9241 ggtgcggcgt cggccgggac cgcgccgaac agcgtcagcg gaagggccac cgccgcgagg
     9301 gtggcgaccg ggtaacacat ccctcggatg tgcctcatcg tgatgttcct ctcgtcgcag
     9361 agaactgcct tcatgcaccg ggccggatga acggcgccgg cgccggacgg cagcctcgcc
     9421 cgacgagggc acgcggcggc acgcgacacg tgcggtcgca ccaacagttg gcttgatctt
     9481 gttcagcgcg tacccgaccc ctcggcatcg ccgacggtct gtccgccccg ctgccggcat
     9541 ccacacgccg atcgaaaacc ggcgcgagcc gatcctcagc cccaggccca tcggggacgt
     9601 cgccggtgca gcgctcgctc gtcctcaccc atttcgagca caaccaccta ccggcaattc
     9661 accgagatca cgtcaccggc tctttccacc acagtcgccg cgcatcgacg aagcagcgca
     9721 cgacgttccg gcaacatgga cgagcttccc caggtcgccg gaccggtggc ctcctccgtt
     9781 cccgccgcca ccaccgatgc gttcgcgctc gccgaaccat tcaacggacg aaacaaaaaa
     9841 gcacagaaat gcgaccgata aaggggacga caccctcccc cggtcgggaa accagcttcc
     9901 acctcgcatt caattcgttt cccattcatc tgcaagagcg cttcgcgact ctcatttcca
     9961 caggggaaac ggcgccgagt ggaagcgggt tcacgtgggc atgcgttcgg aggacccggc
    10021 cattctgcgc gacatcgtgg ccgccgaaat cgggcgcgcg ggtgcgcggg actggtcggt
    10081 cgccgaggaa gacttctggt gcaaggtcac ccccgacgcc tacccgatgc ccgaccaggg
    10141 atggaagctg cacgtctccg ccacgatgct ctccgccccg ctggcgctcg cccgcgtctc
    10201 gcgcgtcctc accgaggccc gttgcgcttt caagttcccc gcccggctga gcgactactg
    10261 gaaactcctc gaaccgcact gcagccgggc gcaggccggg aagttcatca ccgtctatcc
    10321 cctcgacgac gccgagtcgg tgcgcctggc cgccctgctc gacgacgcca cccggggact
    10381 tcccggcccg gtgatcctct ccgaccgtcc gtaccggaag ggcggcatcg tccattaccg
    10441 ctacggcgcc ttcagcgggc accgcgtgct cggcaacgac gggttctacg agattcggct
    10501 gcgttcgccg cagggcctgc tcgttcccga cgaacggcgg ccgagcttct ccccgccgcc
    10561 gttcgcgacg tgcccgttcg aggttccggc ggcgagcccg cgcccgcggg cggccgcggt
    10621 gatgctcaat gaccggttca tcgtccgcga agccgtacgg catgcgaacc gcggcggcgt
    10681 ctacctcgcc gaggacacca ccaccggcca cgacgtcgtc gtcaaggagg ggcgtccgca
    10741 cgcttgcgcc gatctgagcg gccgcgacgc gcgagatcgg atcgcggccg aacgttcctg
    10801 cctggaagac ctcgccacga ccgggatcac gccggccgtg gtggacttct tcgagcaggg
    10861 cggccacacc ttcctcgtcg aggagttcgt gccagggatc accctgcagc gctggtcgga
    10921 cgagaacgcc ggaccgctgg gcgaggacgg gttcggcagc gcggcggcgc aggtcctgcc
    10981 cgtcgtcagc cgcctgaccg cggtgctcaa ggcgctgcac ggccgaggct acgtgttcgg
    11041 tgacctgtcg ccgaacaatg tgatgctctc ccccggcggc gaactacggc tcatcgacct
    11101 cgaacacgcg gccgtgccgg gcaccaccgt catggtgggc gggactccgg gctacctcgc
    11161 cccggagctg gcgggccaca cgggagagtt ccggcccgcc ccccacccga gcgccgacct
    11221 ctacagcctc ggcgcgatcg tgtacttcct ggcggtcggc gcccacctgg acccgccggg
    11281 ccccgaccag gcggccaggg tggcggcggt cgcggcggcc aaccccacgc tcgccctgct
    11341 gcgaccgctg gtggagggcc tgctggcgac agagccggag cggcgctggt cgctggaccg
    11401 ctgccttcgc ttcctcaccg agaccgagct cgccccggag cgggccaccc cccgccacgg
    11461 gacccggcca ccgcggcgga tcggccgcct gatcgacgac gggatcgcgc acctggtgga
    11521 gacgatggac acgagcgagg acgccccgtc gccgtggccc aacgccgccg acggcatcga
    11581 agccgatccg tgctcggtca acggcggcgc ggcgggagtc ctcggcgtcc tggcgcgggc
    11641 cgaaccgcac gcgccggcga ctgcggaact cgcccgctgg ttgaggcggc ggctggcggc
    11701 cgaggacgtc tggccgcccg gccttcactt cgggcgttcc ggcgcggtgt gggcgctgta
    11761 cgacgcggcg acggccatgg gcgacgccga gctggcacgg ttcgcggtgc gggcagcgcg
    11821 gcggctgcct accggccacc ccagctccga cgtgacgcac ggcctggccg gatgcggcat
    11881 gacgctcttg cacatcgcac tggcctcggg agatctcgcg ctgcgagacc gggccgccga
    11941 gaccttccgg aacctgcatc aggcgcggtc gtacggcgcc ggccgcccgc agtggccgac
    12001 gccgcagacg ttcgactcgg gcctggccgg ggccaaccac ttcggtttcg cgcacggcat
    12061 cgccggcatc gggaccgcgt tgctccacgc gggccgggcc ctccatcagc cggactggac
    12121 ggcgaccgtc cacgagatcg ctcgcgccct ctacgaacat gccgaagtgg acagcgacac
    12181 cgcgtggtgg ccgacgcagc gcggcgacct gtcgacggtg cgcccgcgcc ggccgtactg
    12241 gtgcagcggc tcttccggga tcggctcctt cctcgtgcgg tactggcgcg ccaccggcga
    12301 cccgcccgcg ctggacctgg cgcgcaaggc cgcggcggcc gtgcaccgca cccgatggca
    12361 gtcaggaccg gtgccgtgcc acggactgcc cggcgacggt gaattcctgc tggacatggc
    12421 cgatctcacc ggtgacgacc gctaccagcg gtgggcgcgc gacctggccg gatgcctgga
    12481 gatccgcgcg gccgatcgtc gcggccgcct gctcgtcccc ggaccccacg gagacttccc
    12541 gccgaccttt ctcgccggta cggcggggat cgtcgccttc ctcctgcggc ttcgcgaccg
    12601 gtccgcccgg ttgtggatgc cggaggaggc ccccaggctc gccgttcccg cagcgggacg
    12661 gcgatgacag acggccgcac cacgggcggc cccggcattc acaaggaggt gaacgaccat
    12721 gtccttcgac gttgaggacc tgcaggcgct ccaggagctc gagcccggcg ccaacgaggc
    12781 gctccggctg accaactgca tcaagcactt cggctgcacc gacaactgac agccgaaccc
    12841 gcccgcccgg acacgggcgg gcgggggtct gttcgaccac caggcgttcg atacgccagt
    12901 cggttcgata cgccagtcgg ttctacacgc cagtcgttcg aagtcgttcg atccaccaga
    12961 caaggacagg cccgggcccg tgcacgatcg tcccctcgtc gcttcggaga aggctcccgc
    13021 caccggcacc tggcgcaggg tcgtgcggct gttcatgccg caccggctcg ccatctgctt
    13081 cgtcgtcctg ctcgtcgtgg cctactccgc gctgaacgcc gccgtcccgt tgctgaccca
    13141 gctggtcttc gaccgggcgc tgttcggcgc gggcggcccc gatctgccgc tgctcgcgct
    13201 gatcgccggc ctggcggcgg ccaccgcctg cgcggtgggc gtggtggatc tcggccagac
    13261 gtgggtgtcg gcccgcgtcg cgcagcaagt ggtgcacgcg ctgcgcgtgg agctgttcgg
    13321 ccgtctccag cgcatgccgc tggccttctt cgcagcgaca cgaggcggcg agatccagtc
    13381 gcggctggcc aacgacaccg ctcagatcga gcacgccgtc aaggacaccc tgcccggcac
    13441 gctgtccggc gtcatcggat tcgtggccgc ggctggcgcg atggtggcac tctcaccccg
    13501 gctcgcgggc gccgccctgg ttctcgcacc gatcgtcgtc tgggtggcct cccgctccgg
    13561 gcgagcgctc aagaacgtgt cggaggtgag ccagcgctct cgcgcgcacc tgtcgtccat
    13621 cgtggctgag cggctgtgcc tgggcgccgt caccctggcc agggtccacg gcagaagcgc
    13681 ggacgaggcc ggcaggttcg ccgcggagag ccggcggctg atccggctcg gggtacgctc
    13741 cgggctggtg gcccaagggg tgctgagcgc gggacacgtc ttcttcgtgc tgacccccta
    13801 tctggtgttc gtggcggcgg ggctgtccga tgggatcacc cccggcacgc tggtcgcctt
    13861 caccgtgctg caggccaggc tgtaccagcc tctgtggcaa ctcctgcacg tctccaccga
    13921 gttccgttcc gcccagggag ccttcgagcg ggtcttcgac tacctcgaca tggagcccgc
    13981 gcccgagctg gagcccgggc ctgatccacg gccggccccc tcccccgggc ccggcgcgct
    14041 caccgtccgt gaggccactt tccggtacgc cgcggaggat cgggaccgtc ccgcgttgga
    14101 cggcgtgagc ctcaccctcg cggccggatc caccacgctg gtcgtcggtc cgagcggctc
    14161 gggcaagacg acactcggcc acctgctcgc cggcctgcac gcgcccaccg aggggtcggt
    14221 ccgcgtcgac ggggcggaga tcggccggcc gtcgcccggg cgggtctgca tcgccacgca
    14281 ggagcccttc ctcttccagg gctcgatcgc cgacaacctc cggtacgccg cccccgacgc
    14341 caccgcggac gatctcgtgc gcgcctgccg gctcgcccac gtccacgagc ggatcatggc
    14401 actttcggac ggatacgact cgctggtcgg agagcgggga gcgctgctgt ccggcggcga
    14461 acgacagcgc atcgccctgg ctcgcgcgct cctggccgac gcgtcagtgc tggtgctcga
    14521 cgaggccacc tccgcgctcg acccgatgac cgagctggag gtcgtcaagg cgatcctggc
    14581 cgagcgggcc ggacggacca cggtgatgat cacccacagg ttcggcgtgc tcgactcctt
    14641 cgacaccgtc gtggccctgg acgagggccg ggtggcggaa cacggagctc gcctcgacct
    14701 gctcggcgac cggcacgggt ggtacgcgcg gacggtccgc gctcagaccg gcgccgcatg
    14761 agccgaacgg cccctttcgg gcgagcgagg gccggacgag gcccggcccg gcccggtcac
    14821 cgcaccgcgc ggcggtgacg tgagcgtcac acctgagggg gcttcacgta cgtcacccgg
    14881 acgttcaggt aggtggagcc tccatagtcg tgcccacgga tggcgagcag gttgcagcac
    14941 tccaggtact ccgccgggac gacgacgtcg atggcgccgg tcctgcagta accgctcctg
    15001 accgattgca cgagatggcc gttcagatag acctgggcgt cgttgtctat cgttccttgg
    15061 atgcggacct gctgcgcgtt gcgcgggaga tggagccagt ggcgcaccag gatgtcggtg
    15121 ttgcgcgccc atgacgtctt gacgttctcg ggagtgttga acgagcagcc gctggcggtg
    15181 ccgaagccgg cctgacccgt ctgccactca ctgtcgtcga agccccgctc gtagaacagg
    15241 ggaacgtcgg tcgcgggcgg cacctggcgg tacctccagc ccgtgctgtt gtagtcgagt
    15301 tccgtcacga cggtctcgcg cccgttcgcg ggctgggctg cggacgccgg tgaggtgacg
    15361 gacatggcca tggtggccag cagcgcagcc gccgccactc ctgtggacag caagcgcgat
    15421 ggtttcggca tgaacggtct ccttgtcaat ggctcgagat ggtccgtacg ggagcgcacc
    15481 aaaattcagg tatggccatc gaaggggcca aaacttttgg tgcgctcgcc gattcgggga
    15541 cacagaacca cagccgccgc cgcgtagatg gcggtgacca cggcattcgt tattccttgc
    15601 cgaaaggttt ccgcttctgt tccggtgctg aaccgagcgc gaacggctcg tcaggcgagg
    15661 gcgaccaggt cgcggtagtc ctcgctccac aggtcctcgt ccgcgtcggg caacagcagc
    15721 acacggtcag gacgcagggc gtcgatggcg ccctggtcgt gggtcaccat cacgatcgct
    15781 ccagggtagg agccgaccgc agccaggacc tcgtcgcggg agacggggtc gaggttgttg
    15841 gtcggctcgt ccagcagcag cacgttcgct ccggagtgca ccagcccggc cagggccagc
    15901 cgggtcttct ccccgccgga aagcaccccg gcgggcttgt ccacgtcgtc gccgctgaac
    15961 aggaacgcgc ccaggacctg ccgggcttcg ccgtccgtca ggtgcggggc ggcgtcggtc
    16021 aggttctgcc gaaccgtacg atcggggcgc aaggtgtcgt gttcctgggc gaaatagccc
    16081 aggcgcagcc cgtgcccgcg caccactcgc cccgcatccg gcagctcctc accggccagg
    16141 atgcgcagca gggtggtctt gcccgcgccg ttgagaccga gcacgaccag gcggctgccc
    16201 ctgtccacgg ccaggtcgac cccgtcgagg acctggcggc cgtcgtagga cttggccagg
    16261 ctgaccgcgc ccagcggtat ccgcccgcac ggggccggtt cgggcagccg gattctggcc
    16321 accttctcgg tccggcgagc cggttccagt tccgccagca tgcggtccgc gcgccgggcc
    16381 atgctgcggg ccatgacggc ggtggccgag cgggccttca tcctgtccgc ctgcgcgtgc
    16441 agcgtggcgg ctttgcgctc ggcgttcgcc cgctgccgct cccgccgccg ccggtccgcc
    16501 tcgcgctggg tcaggtaggc gtcccagccg gtgttgtgga tgtcgatcgc cgcgcgggtg
    16561 gcgtccaggt ggaagacccg gttgacgacc tcggcgacca gcccggtgtc gtggctgatc
    16621 aacaccagac cgccctgatg gcctcggagg aaggtacgga gccaggcgat cgagtcggcg
    16681 tccaggtggt tggtcggctc gtccagcagc agcgtgccgc cgtggccggc gaacaggatc
    16741 cgggccagct ccacccggcg tcgttgcccg ccggacaggt tgccgaccgg ccggctcagc
    16801 acccggtcgg gcagcccgag cccggcggcg acccgagcgg cctcggcctc cgccgcgtac
    16861 ccgccgccgg tctggaatgc cgcctccgcg cgggcgtagg cgttcatcgc ccgctccagg
    16921 gcggcaggcc cggtggccgc ggccatcgcg gcctcggccg cgcgcagccg gcgcagagcc
    16981 cggtccaggc cacgggccga caggatccgg tcggtgacgg tcacggcggg gtcggccgcg
    17041 cgcgaatcct gggcgaggaa ctccaccgcc ccggtacggc tgatcgtccc ggcggccggc
    17101 ttggccagcc cggccagggc ggtcatcagg gtggtcttgc ccacgccgtt gcggccgatc
    17161 aggccgatgc ggtcgccggg ggacaccgtg aaggagatgt cagagagcag caggcgggca
    17221 cccgcgcgca gcgcgacatc gcgaacagta atcatgtcga aacgctccga gaaagctgga
    17281 ggacacactt ctggcgtgga agcgggtcct cagctaggag actcggggcg tcgacatgcc
    17341 ccccatgcta gcccacacgg tgggcgccgg accggatccc tgtgcggggc cgggccgcgg
    17401 tggccaggtc caccggcacg gggagagagc cgacgtcgag gcgcgggttc tcgcgggtgg
    17461 gcgcgtccgg cgactcatcg agcacgacca gatcctcggc ggtacgggtg ccggtcaccg
    17521 gtgtgcgccg gcgtagaagg cacgggcggc gaagccgatc cactcggggc gttcccaggt
    17581 gctccagcgg gcgcgggcct gttcgtcgat cctcgcggcc gtctcgtcgg cggagactcc
    17641 ggccgcgcgc agccgtgagg cctccccgta cacgtagccg aggtagtcgc ggacgtcgcg
    17701 gatcaaggag acgccggcca cctccccgtg gccgggcacg acgatctcgg gctcgcgggc
    17761 ggcgagttcg tcgagcacgc cgatccaggc cgcgccgtcc acgtcgacgt cgtacggcgg
    17821 gaagtacggg gcgatcggga agatgcgggt ctcgatcagg tcgccgccga acagcacccg
    17881 gtcgtcgatg acgatgacct ggtcggagcc cgtgtgcgcc gggccgaccg cccgcagctc
    17941 cgccttgcgc ccgcctaggt cgagctcggc ccggccctcg tagacaaggt cgggatcgac
    18001 gagttcgacg ccttcgagct cggccgccgc ggcggcgctc agccccttga acatctcgac
    18061 gtaggcggcg cccttgcggt gcagctccgc gcgctgggag gcgttgtaga cgatcgtcgc
    18121 ggcgcccttg aacgcctgcg ccccgaaccc gtgctcgggg tggaaatgcg tgagggtcag
    18181 gtacaggtgc cggtcgccgg ccaggcgccg ggcctgctcc aggacgtggg cgccgttgcg
    18241 ggggcccatg cccgtgtcga tgaccagtgc ggcgtgctcc cccacgacga tgccgacgtt
    18301 cgggacgagc tcgacgcggt tgtcagggat gacgtacacg ccgtcggcca gctcgacggg
    18361 cccgccgcgc acgatcggcg gcgggctcgt ccgtacgtcg ggaaggtcgc tcaggtcggg
    18421 ggacgggttc ggcgtcaggt cggcggggca catgatccgg ctccaatctg aacagtgttg
    18481 agatgcctgg gagcgtagca gagaactgag cagtgttaag atcgggcgat ggcaaaaggg
    18541 cgataccacc acggcgacct gcgcagcgca ctgctcgacg ccgccgaggc cctcgtacgc
    18601 gagcgcggca ccgacggctg gtccctgcgc gaggcctcgg cgcgcgtcgg cgtcagcccc
    18661 agcgccgcct accaccactt cgcctcccgc gacacgctgg tgcgcgccct gtccgagcgg
    18721 acgctcgcct ggctcgggga gcgcctgcgc caggactgcg agcacgcgtc cggccagggg
    18781 gacgaccctc agcggcggct gatcgccctg gggcgcagct atgtgagctg gtcgctcgac
    18841 gacccggccg tcgcccggct cgtgctgcgt ggcggcgcca ccgctccgga ctccgccatc
    18901 tccccccacc cgcacgacgt gctcaccgcg gaactcgacc ggctcgccga tgccggcgcc
    18961 ctgccggaac ccgctcgaga gggagccgag ttcgtgctgt gggcggcgct gcacgggctg
    19021 gccgtgctgc tggccgacgg cctggtccgc ttcgacgacc cgcgcgcggt cgagctccag
    19081 accgagcgcg tggtccgtac cacgctcaac ggcctggccc aggaggcgtc gcacgcggcg
    19141 ggccgccccg cgggccgctc ggctcacacc gagcgcctgg cccgccgttc gcgtggatga
    19201 caccctttcg agggggtacg tctttcgacc ggcggcgcgc cggtgacggt cacgcccgga
    19261 tcccggcctg ctgtgtgtgc tggggggcta cgcaacatca tgcggccctc gaccacgccc
    19321 cgccgggacc ggcccgaaga gctcgccctc caagacgtag agacggattc tcctccgccg
    19381 cgatgagttc cgaccccgcc gccggtatgt actcacgagc tcgtcggagt acctcgggcg
    19441 aaccgatcac aagggagaat cgaaatgtcg aacagtcgtg cggcagacga ggccgccatc
    19501 caggccgtgc tggtcgactc ctacaaggcg tgggaggcag gcgacgccga cggcatggtc
    19561 gccaactaca ccgcggacgc gaccgccatc atgaccggct cgctccgcga cagccgggag
    19621 gtgatccgtc agagcatggc cttggccttc gaggggccgc tcaagggcag ctcgacctac
    19681 aacaagcagc tcggcatccg cttcgtcggc agggacgggg cgatcgtcat cagtgagtcc
    19741 gcgatcctgt tccccggcga gaccgaggtc gcggacgagg cgcgtaaggt gaactgcacc
    19801 tgggtcttcg agaagcggga cggccagtgg ctgatcgccg cctatcacaa cagcccggtg
    19861 ctggcgcctg cgctgtgaac tcttccctgt aaccagcagt gatcgcgtgc agggccatga
    19921 ccaacatcgg acggaagccc tgcatcgcgg tgagcccggt tccttggtgt gacgtttcat
    19981 accggcgccc ctacctacga gatttgagat gtatgccatg gcaggccgtt gatgaccgcg
    20041 cggggagggc tatccgccca ctgcggatgc tcactgcagt cgccggatat ggtgactgcg
    20101 gctgcagcgg agacgggggg cgccgcgtga tgacggggca ggaaggcttc gatcgtcgga
    20161 tcgaaccgtt ccggacggag ttgctggcgt actgctaccg gatgctcgga tcggctcacg
    20221 acgcagagga cttggtccag gacacgtacc tgagggcgtg gcgggcacgg gagcagtacg
    20281 acgacacccg cagctcactg cgcacctggc tctaccggat cgcgacgaac gcctgcctga
    20341 ccgccctgga ggtccacggt cgccggccgc tgccgtcggg gctggtggcc gcgtcggatc
    20401 cgctcgggcc gctcgtccag ggagagcacg tcccctggct ccagcccttg ccggactcgc
    20461 tgctggacgc gggcgatccg gctggggccg tgatggaccg cagcagcctg cgtctggcgt
    20521 tcgccgccgc cctgcagcac ctgtcggcgc gtcagcgcgg tgcgctgatc ctgcgtgacg
    20581 tgctcagctt ctccgcggcc gaaacagcgg aaatcctcgg caccaccgtc gtgtcggtga
    20641 acagttccct gcagcgcgcg cgtactcgcg tcaaggaggt cggagtccgg caggaacggg
    20701 tcagcgagcc gcctgcggcc gagcagcggg cctgggtcga acgctacatg agggcattcg
    20761 agctggccga cgtcgagggc ctcaagcggc tgctcaccga ggacgtgatc atggagatgc
    20821 cgccgatgct caactggttc gccggacgcg acaactacgg cctgttcatg gaatgggtct
    20881 tcggggcggc cgggaaggac tggctcctca aggaggtcgc ggccaacggc ggccagcccg
    20941 gattcgccgc ctatcaacgc gtcggcgacg ggtactccct gcacacgctc cagatcttca
    21001 ccgtcaccga cgagggcatc agccggaact ccgtcttcca ggaccccgac atctacgcga
    21061 ctttcggcct cgcggccaaa ctcgacgacc agggacttgc catcgccgag gcctaggccg
    21121 tctcccgtga tcatgtgacg gggtctcgga gccagatccg gatcgaggcg acatcgaggg
    21181 ttccttggta gatgcgctcg cgctcgtcga agtgggtggc catcggcccg atgctggcgg
    21241 agcttgttga cgcggcgctc gacggtgttg cgctccttgt accgcatacg ccttgtcacc
    21301 catcgcgcgg gcgggccgct tgcgcggcct gaccggcccg cgccgccgga tgaggccacc
    21361 tcgggagcgg cccagcgcct cccggctcga cgtcacccgt tcgtgatctt catcggcccc
    21421 tttgacggga tgtcgagggc cggggcgcgc cgtgccctgg ccgcgtgctg gtgggcgcgc
    21481 accaccgtgg agtcggcgct gaccgtccag tcctcgccct cggcctcatc gcaccccgcc
    21541 cggagcccat cgaggatccg cgcccaggtc ccatccagcg accagcggcg atgccggttg
    21601 taggccgtac cccagcccgt gctcaccggc agcagcggct ccagccgccc ctcacgttaa
    21661 cgatctacac ccgaccagcg cgaaagatca gttgatcaac acgagtcgcc ttgatcgacg
    21721 gggcggcgcg ggaacggccg tttcgagtcg acggtggctc tcaggatggg aagcgatcgg
    21781 cccggagcga cctctcgctc cccgacacgc tcggccccca tccgcaggta gaacgcttcg
    21841 gcgtgcgggt cggactcgat ggtcaaggta tggaagccgg cgctgcgcgc cgattcgacg
    21901 gcgtgttccc agagcgtacg ccccagaccg gtaccgataa cctcgggttc gaggaagagg
    21961 tccgcaagtt cgccgtgcgg gggttcgcca gagatctggt agtaccccgc cagcgcgcag
    22021 tcccgctccg cgacgacgac acgaccgtca cgaatggcgg cggaactgat cgacaacatc
    22081 tccgccatcc ggtccagcat cgcctgcgga taaccccagt acgccttcga acgccgagta
    22141 agcgcggtga gcgcatccgc ttcaccgggc acggcggctc tcaatatgat cttgttcacc
    22201 accacagtat cgccctccct gtccaaccgg tgcacggcgc gtcgtctgct gaaacgcaag
    22261 gcgatctcga tcgccgtcgc gaccgtctcc gccagcatcg ggccgtggcc acccgaatcg
    22321 gccagtgcgg gtcgatcaca ggggtcagcc cgatgtcgca cgcctcgctg agcagcaggg
    22381 cgaccatggt ggtggccagg tcctccatgc ttcgaggacc cgcacgccgg caacacccgg
    22441 gtgcagtggt tcgtcaccgt gtacacccac gtgctcgggg ctgggcgcgc gcgccgagcg
    22501 ccgagcgccc accatcatcg ccaggcctac ttcgcgaagt tcgtggcgag cttgtcgaac
    22561 tcgcggtccg gcagcgtcct gttgagctcc aggagcttgt cggccagcca gccgaccgcg
    22621 taccgcgtct cgggccgggc ggcctcgacg gcctcccgga tggtggt
//
