LOCUS       NZ_JABWGO010000010     21062 bp    DNA     linear   CON 29-SEP-2024
DEFINITION  Nonomuraea rhodomycinica strain TBRC6557
            NODE_10_length_373004_cov_26.5151, whole genome shotgun sequence.
ACCESSION   NZ_JABWGO010000010
VERSION     NZ_JABWGO010000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nonomuraea rhodomycinica
  ORGANISM  Nonomuraea rhodomycinica
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 373004)
  AUTHORS   Chanama,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2020) Microbiology, Mahidol University, Faculty of
            Public Health, 420/1 Ratchawithi Road, Ratchathewi, Bangkok 10400,
            Thailand
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 26-MAY-2020
            Assembly Method                   :: SPAdes v. 3.10.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013363995.1-RS_2024_09_29
            Annotation Date                   :: 09/29/2024 04:09:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,940
            CDSs (total)                      :: 8,866
            Genes (coding)                    :: 8,758
            CDSs (with protein)               :: 8,758
            Genes (RNA)                       :: 74
            rRNAs                             :: 4, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 12 of 108
            Pseudo Genes (incomplete)         :: 99 of 108
            Pseudo Genes (internal stop)      :: 6 of 108
            Pseudo Genes (multiple problems)  :: 8 of 108
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:20:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 185189
            Orig. end                         :: 206251
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABWGO010000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21062
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21062
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21062
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11062](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11062
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    complement(11..24)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            complement(156..509)
                     /locus_tag="HT134_RS32870"
                     /old_locus_tag="HT134_32855"
     CDS             complement(156..509)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014616.5"
                     /locus_tag="HT134_RS32870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32855"
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="WP_175604364.1"
                     /transl_table=11
                     /translation="MEGSDGIKEFEEAQARLDALISAAARAEARVEEWSAAEFSGRADD
                     GGITAVTDALGTLVRLEISARSRRRLDAASLAHEILTAVTAAEDAAASSRDTLFADLLP
                     ASGGIAPGGPGSA"
     gene            complement(528..923)
                     /locus_tag="HT134_RS32875"
                     /old_locus_tag="HT134_32860"
     CDS             complement(528..923)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014616.5"
                     /locus_tag="HT134_RS32875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32860"
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="WP_175604365.1"
                     /transl_table=11
                     /translation="MRDVEASALNGPEDVVNLLRQADDWTRALNGALTGLAEERLAGTD
                     PSGVVRAEVSGSGRLRGLSIDPRGLRGLDHVQLAHAVQEAIAAAHRTMGDRLTEVMQEL
                     SGPGRSTTGADAADPLDGYIRNVLRGD"
     gene            complement(920..1813)
                     /locus_tag="HT134_RS32880"
                     /old_locus_tag="HT134_32865"
     CDS             complement(920..1813)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS32880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HT134_32865"
                     /product="hypothetical protein"
                     /protein_id="WP_175604366.1"
                     /transl_table=11
                     /translation="MTVPSSSSGEPPKLILPGQTAPTGDRQLHIANANGTVQRTITVSP
                     TPRTDPGFYRRLIQGLNPLRQNNRAAMAVSGLGAAALALDVVATLNMGNPFLFYARREL
                     WKDMAGALEGSRSDLWRSFFDDITPYWKGVAQQTLQQYVRFNINGLYGQLGKISGAMSS
                     TMHSQYKEVMEYDLSVFGLYATSAPILRAVATMSTHPVGRVALMTQVGLFMSAAGNLVK
                     QFADVYNKYESELNKLELKLNDLRGAFYRSGDPSRGARDLHLTDAIADPRLVDEYWVPM
                     NEPEPAKGKSPSKKAS"
     misc_feature    complement(1457..1459)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1827..2330)
                     /locus_tag="HT134_RS32885"
                     /old_locus_tag="HT134_32870"
     CDS             complement(1827..2330)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS32885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HT134_32870"
                     /product="hypothetical protein"
                     /protein_id="WP_175604367.1"
                     /transl_table=11
                     /translation="MSDDHALSFAAGSPSVVSPCPHTPACPPPACLPQSLRAQPARAVS
                     AGQAQPALAVSTRQAPPPDDTGSPNGYDVNEAFIRKFAGTMDSSATGVETVKHWTPRFE
                     GWQLIPMAGVPIAGLLFVNRFNTVSDTWADCAGILSGLLRTDGGKIVKAADNYHAADHH
                     STPA"
     gene            2519..3739
                     /locus_tag="HT134_RS32890"
                     /old_locus_tag="HT134_32875"
     CDS             2519..3739
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019611179.1"
                     /locus_tag="HT134_RS32890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32875"
                     /product="cytochrome P450"
                     /protein_id="WP_175604368.1"
                     /sec_met_domain="p450 (E-value: 1.8e-20, bitscore: 67.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTHLPSFPAVNENPLDTCLRLREIAPVVEVEFPGGVPAYLALTH
                     KAVREILAGDNKTFLRDPRHWPALYDGSIPEDWPLRAIVQGGHLSTMDGGDHRRLRGLV
                     GRAFTPARVQALEPRIQQIIDGLLDDVVAAGDGVDLVPAFTEALPMWVICELFGIPAED
                     RLRLRNWTATLLAHTTPPEVAFATQNELQAFLHELVERKQREPGDDLTSGLVQARDEGD
                     RLTTDELVGVLWLMLVAGHETTVHLLGYAVVALARNPGQLRLAMAEDRWADVVEETLRY
                     RHSVMMTSFRFTAEDVTVAGVRIPKGNAVGVVYQASGVDPAEYGDSADRFDITREQTGH
                     LGFGHGPRYCIGAPLARLESRLALASLYRRLPRLSLAIDPDDIAYSPSFFTIGPLSLPV
                     DLGLTAS"
     gene            3832..4116
                     /locus_tag="HT134_RS32895"
                     /old_locus_tag="HT134_32880"
     CDS             3832..4116
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS32895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HT134_32880"
                     /product="hypothetical protein"
                     /protein_id="WP_175604369.1"
                     /transl_table=11
                     /translation="MYATVRRYEGVTDPAEAARLVNEGFVPLLRDVPGFVAYYWVDAGD
                     GVMLSTSVFEDEAGAEESTKRAAEFVRESLSSLLPNAPQVTAGEVVATG"
     gene            complement(4207..5043)
                     /locus_tag="HT134_RS32900"
                     /old_locus_tag="HT134_32885"
     CDS             complement(4207..5043)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF017206.5"
                     /locus_tag="HT134_RS32900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32885"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_175604370.1"
                     /transl_table=11
                     /translation="MTILVTGARGHVARSLVRQLLDAGEPVRAAGRDPGAARVPAGVEA
                     VLCDLADPATFGKALTGVGKVFLYAEPRGVDGFVAAAASAGVEHIVLLSGVLHDPASAD
                     AISRMHGDAEQAVTRSGVAWTFLRPGGFATNTLQWARSVRDEGVVRDPFPDSRSAPVHE
                     ADIAAVAVRALTEPGHEGAAYTLTGPELLTRRRQAELIGEAVGRPVRFDVQDLEEYRAE
                     LGAWTTPQVAEAVIRESAAAVDRPLPPTDTIAKVTGRPARTYGQWARDHAADFGAA"
     gene            5128..5985
                     /locus_tag="HT134_RS32905"
                     /old_locus_tag="HT134_32890"
     CDS             5128..5985
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017588967.1"
                     /locus_tag="HT134_RS32905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32890"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_175604371.1"
                     /transl_table=11
                     /translation="MNREELGSFLRSRRERVSPGEVGLAPGGRRQTPGLRREEVALLAG
                     ISVDYYIRLEQGRGPQPSAQVLAALSRTLRLSGDEHDYLLRMGDQAPAPAGSSPEVPAN
                     ALRLLERLDEVPAMIVNTRGDLLAWNEMLVALIGDPADIPRRERNTLRWLFGTEPNLPH
                     NRVELARQAVADLRASGRYPDDPGVRQLVDELTSTSRLFAELWAAREVEVQRTMTKRTT
                     HPVLGEMELDCEVLSLPGGDHRVILYTAAPGTPTHDALKRLRSSRGRPPRHAGCVIPTG
                     PADR"
     gene            complement(6017..6859)
                     /locus_tag="HT134_RS32910"
                     /old_locus_tag="HT134_32895"
     CDS             complement(6017..6859)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891881.1"
                     /locus_tag="HT134_RS32910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32895"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_175604372.1"
                     /sec_met_domain="APH (E-value: 9.1e-20, bitscore: 66.1,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDRVPDDLLAMADALVPGARLDSARFVRGGIHDVVLLPGVAAVR
                     VSRRPTGAEALPRRTEVLRLIAAAGLPFAVPEPLTPVTWFEERAAVAVSWIDGAGHPEG
                     VGDPAGTGALLSAIRELPVTPELRALLPAPREHEGRDNWAAILAEEVIPRFPDRWREEG
                     RRRLAEATALEPVPDTLVHGDLVGSNVHWGEDGRLIGVLDWDRAHLFDPAIDAAFMAWH
                     GWDHLRQAVDRETYRRARVWDRTFGVDHLVAVLELGGKPLRYVDSYVDHIVAWLERYA"
     misc_feature    6811..6825
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            7104..7334
                     /locus_tag="HT134_RS32920"
                     /old_locus_tag="HT134_32900"
     CDS             7104..7334
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS32920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HT134_32900"
                     /product="hypothetical protein"
                     /protein_id="WP_175604374.1"
                     /transl_table=11
                     /translation="MTVNTEIRAGVPALGLALTTAGTAAAGVAAWLAQARPSRLIGGGS
                     WSPDQATEVALGRSFDVVIHLHKVTAARLLP"
     gene            complement(7508..8455)
                     /locus_tag="HT134_RS32925"
                     /old_locus_tag="HT134_32905"
     CDS             complement(7508..8455)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009080205.1"
                     /locus_tag="HT134_RS32925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32905"
                     /product="DUF5829 family protein"
                     /protein_id="WP_175604375.1"
                     /transl_table=11
                     /translation="MLINRTLRTITVLTAAFTVALTGAVAGGASAATADEAQPKTDRQL
                     LFYNHAYSVVDKETADAVENSEYLKKFANFEVRTTTGGGMTWKGRYLKGRETYLELFSV
                     GDLPGQDAEFGSAGMAVSAERAGDLATVGERLKAQGITPVPYRQTRDFGDGVKVPWFDT
                     IRTFSDQYEAFDPWAMEYLPEYFADPRSKTEPESFPGDVGRERYLPDDYRDRLMRDITA
                     IRMGVPARDLATMVPLLRAGGFTVQSLANGGVVATGGGTRIHLDSVPREQAGLKRVDFV
                     LNKSLAYMTEERIGRSTLAVGPGAHAVWTFDAPQ"
     misc_feature    complement(8435..8437)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(8498..8515)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.45"
                     /tool="antismash"
     gene            complement(8509..9462)
                     /locus_tag="HT134_RS32930"
                     /old_locus_tag="HT134_32910"
     CDS             complement(8509..9462)
                     /EC_number="2.7.7.6"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009083648.1"
                     /locus_tag="HT134_RS32930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32910"
                     /product="RNA polymerase subunit sigma-70"
                     /protein_id="WP_217708649.1"
                     /transl_table=11
                     /translation="MAEIAFEEQVAAYRRELLLHCYRLLGSLTDAEDVLQETLLAAWRG
                     LDGFEGRSSLRSWLYRIATNRCLNALRDRGRRVPPEPKPPFEPPPPSRHGDVPWLQPYP
                     DTLLVPDAAPGPEARCTAREAVELAFVAALQRLPPRQAAVLVLRDVLGYPPGEVAPMLG
                     VTPTAVKGLLQRARTSLARQPERGGGRHPEAPAPGSARERELVRRFADAFTADDIDALV
                     TLLTDDAWLAMPPAPHEYHGVPAIASFLRASTAWSADLPVLLVPTRANGQPAFTCRLGG
                     EPAGVIVLTLAGDRVRGITRFLVLDDGFLRRFEPRC"
     gene            9521..9898
                     /locus_tag="HT134_RS32935"
                     /old_locus_tag="HT134_32915"
     CDS             9521..9898
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024092.5"
                     /locus_tag="HT134_RS32935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32915"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_175604377.1"
                     /transl_table=11
                     /translation="MSGSALQIALAHHRAWTGKDLDLAMSYLADDVVCDAPAGRLTGVE
                     AYREFLGPFAEHLLVRAELIAAFGDDETALIMYDAETVPARSAPAAECVTVRDGRIVHN
                     RFVFDRTPFEEFRRRQEQSRA"
     aSDomain        10001..10267
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HT134_RS32940_Pantocin_Microcin_RRE.1
                     "
                     /evalue="4.30E-17"
                     /identifier="RREFam017.1"
                     /label="HT134_RS32940"
                     /locus_tag="HT134_RS32940"
                     /protein_end="89"
                     /protein_start="0"
                     /score="53.0"
                     /tool="antismash"
                     /translation="MRLPRVKPEHAPQRLGDGTVRLGGALYGIASEIADADGWAWTALS
                     LMDGTRPPARIAAELRARHPVLTCEEAEDIVATLVSSGHVEDAA"
     gene            10001..11062
                     /locus_tag="HT134_RS32940"
                     /old_locus_tag="HT134_32920"
     CDS             10001..11062
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013094.5"
                     /locus_tag="HT134_RS32940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32920"
                     /product="HesA/MoeB/ThiF family protein"
                     /protein_id="WP_175604378.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 5.7e-16,
                     bitscore: 53.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 5.5e-44, bitscore: 144.9,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLPRVKPEHAPQRLGDGTVRLGGALYGIASEIADADGWAWTALS
                     LMDGTRPPARIAAELRARHPVLTCEEAEDIVATLVSSGHVEDAAPEPCPELTEREKERH
                     SRTRDYFRWVDLTPRDHGWEPQVRIKNARVVVLGLGGTGSHVAWTLAAAGVGRLHLVDP
                     DVVELSNLNRQILYTEPDVGRLKAEVALDRLRQVNSEIGITAEAAAVDGPGRLARLIDG
                     FDVLALCADRPRGPYGIQSWANRVCAEAGIPWVSGGYNGPLVSVGVFGPGGPCYECVRA
                     GIPSRPGADYAWPGVTGASAGLSGHLVAHDVLALVTGVMSTPPGYFHGVMLLDPDGHVY
                     ARHPSRPDCDICS"
     misc_feature    11076..11089
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.9"
                     /tool="antismash"
     gene            11130..11252
                     /locus_tag="HT134_RS47240"
     CDS             11130..11252
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS47240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_281387796.1"
                     /transl_table=11
                     /translation="MSNTPAPEAQQERKPRKRIVVRRLDKVGPTAWAPSQGNSN"
     misc_feature    complement(11342..11360)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.48"
                     /tool="antismash"
     gene            11343..11927
                     /locus_tag="HT134_RS32945"
                     /old_locus_tag="HT134_32925"
     CDS             11343..11927
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF045158.2"
                     /locus_tag="HT134_RS32945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32925"
                     /product="DUF6879 family protein"
                     /protein_id="WP_175604379.1"
                     /transl_table=11
                     /translation="MSDVLNRLRTVPAQVMDAAEYGADFAGALAATSGVVWKLERAQHF
                     DEGDLPSYLAMVEGDWDRAMELAERMRPGFRDDNPARLDFRRIRVVEEPFTPYLRWELA
                     LLAMRAEEGENGRVVPVSAVRPYEDGGPVPELVLLRPTLLYEVLYDEAGRHVGARRITD
                     PRVVEPCVPVLAGLFERGEDLRAYWVRKRTA"
     gene            complement(11966..12538)
                     /locus_tag="HT134_RS32950"
                     /old_locus_tag="HT134_32930"
     CDS             complement(11966..12538)
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012855257.1"
                     /locus_tag="HT134_RS32950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32930"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_175604380.1"
                     /transl_table=11
                     /translation="MARILLLHSQYGLRPAVHQAAGRLRAAGHEVHVPDLYDGRVVGTP
                     EEAIAIKDELGRDELLKRAVAAAAPLSGQGVVYAGLSLGGALAQNLALADENARGLLLM
                     HGTSDLPEGAFLDDLPVQLHVADPDTYEPVDWQNTWYLLMRRAGADVEVFRYPGAGHLF
                     TDPDLPDHDPESAERAWATALGFLADL"
     gene            12591..13130
                     /gene="lepB"
                     /locus_tag="HT134_RS32955"
                     /old_locus_tag="HT134_32935"
     CDS             12591..13130
                     /EC_number="3.4.21.89"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="lepB"
                     /inference="COORDINATES: protein motif:HMM:NF021981.5"
                     /locus_tag="HT134_RS32955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32935"
                     /product="signal peptidase I"
                     /protein_id="WP_175604381.1"
                     /transl_table=11
                     /translation="MIRPRLSALSLVLLLTPVAGCASADLGIFDRTGYTMTSQAMEPTI
                     KHGAHMSVRRVGDAYVPRVGDVIVYREPEGWSVGTPDPERTYVSRVIGVPGSTVKCCDS
                     HGRLELDGKALDEPYIAKPPASDLDFDVQVPRDRIWIMSDNRHSALDSRSHQDAPGTGT
                     ISVSDVVGVVEDPRGS"
     misc_feature    12606..12608
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13127..13483)
                     /locus_tag="HT134_RS32960"
                     /old_locus_tag="HT134_32940"
     CDS             complement(13127..13483)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541168.1"
                     /locus_tag="HT134_RS32960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32940"
                     /product="VOC family protein"
                     /protein_id="WP_175604382.1"
                     /transl_table=11
                     /translation="MLHHVQLACPPGSEQALRDFYEGVLGLAEIPKPPVLAARGGCWFR
                     GHGIELHLGVEADFRPARKAHPGLLVSGLDAWAERLRAAGYPVTFDDDFPGMRRFYSED
                     PHGNRLEFLEPAGA"
     misc_feature    13503..13519
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.48"
                     /tool="antismash"
     misc_feature    complement(13503..13519)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.15"
                     /tool="antismash"
     misc_feature    complement(13506..13522)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.32"
                     /tool="antismash"
     gene            complement(13509..15419)
                     /locus_tag="HT134_RS32965"
                     /old_locus_tag="HT134_32945"
     CDS             complement(13509..15419)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017539.5"
                     /locus_tag="HT134_RS32965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32945"
                     /product="NACHT domain-containing NTPase"
                     /protein_id="WP_175604383.1"
                     /transl_table=11
                     /translation="MRQRSGLRVWYWALILALFLVPVGGVTLGWFFLSEGWENADQWAS
                     IVSAVVALIGGSVALLRWLRGRAATAAAADPDDQEVSAEVMAERLARLAARVRQVWESE
                     ELRQRLLDPRPLPVSWRTLGPPVSDHWRVIHGGDEPIDLDGSLDELYDIVRTRLRAPRL
                     VILGEPGAGKSSLIMRFALAWLARRDDDSPVPVILRLSTREPADGKRLTTWIYARLRAD
                     YGFHESVSLDRLLPILDGLDEMPEPLRTRTLREINATFGATSPVILTSRSHEYAATIDH
                     PDADVLTAAAVVELNPLDAEAIREYLTITTKPARLPRWERVFGELTRAPDSETARGLST
                     PLALSLARMTYAEGAEDPDLLLTFRTRHAVEAHLLAHLVPTVYAGRDDLPGPSWGHRDV
                     HSWLSHLARRFPKHGISRESLTDEVPSPAENLIFSSLAGLAAAVAFAVAASPVVGLVLG
                     TTIALVVLVYVFAGDHSLSPVFLSPMTLLTAGGPAAVLFAAVHWYLSAMQGSTAGQAAG
                     LALVTSLWLFVVLSRGVITFIAAVIDFALTLLVTTGPSSPWSLGLAAVLTLVLVTLLEN
                     SWVRFLIARVFFTLRGVLPWRVLAFLEDAHRRGVLRKVGGMYYFRHDLLREQLATSADV
                     T"
     misc_feature    complement(14826..14828)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15456..16499)
                     /locus_tag="HT134_RS32970"
                     /old_locus_tag="HT134_32950"
     CDS             complement(15456..16499)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014325.5"
                     /locus_tag="HT134_RS32970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32950"
                     /product="ion channel"
                     /protein_id="WP_175604384.1"
                     /transl_table=11
                     /translation="MPLFLARMLARLVLLGTWWTPVLVFTLVFLTSWPLMALAEPAGSE
                     IVAPGNYWWYFVVTASTVGYGDLYPETAAGHAVGAYVIAGGIATLTTVFTRFASSLERA
                     KGRRMRGAVTVDMSGHIVLLGYTPGRTEQMVDELAADGSCRIVLCAWDEVQTHPMPERE
                     VTFVRGDLTDDKVLLRAGVHRAHSVLVDARDDNEALAVAITADHVAHGAHLVVALRDVS
                     RVRQLRYVRDTLRCVQWHSPYMITEELRDPGIAEVYTQLMTHGDAETYSVRLPESVGPV
                     LVDRCQVSLGRRCGATLLAARTGDELLVNPDWRTELPAGSVLYYVASRRLTPDELAAAL
                     GAEGRAG"
     gene            complement(16585..17187)
                     /locus_tag="HT134_RS32975"
                     /old_locus_tag="HT134_32955"
     CDS             complement(16585..17187)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024248.5"
                     /locus_tag="HT134_RS32975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32955"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_175604385.1"
                     /transl_table=11
                     /translation="MTDEAASPESFLLDDPARLKALAHPMRRLMLRHLGVHGPATSTTL
                     GELLGAKTGTTSYHLRQLEKYGFIEEIPERSTGRERWWRKAPAPRDMRLPAPDRLAPED
                     RPILAEFHRLGLEEDLRLLEGLPRLYERDPARVKASRGLGWMTDEEFEAFFEGYMELLL
                     RHSHSREEAPPGARPLYLRLWAFPATASEDPEGTPDA"
     misc_feature    complement(17240..17254)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.74"
                     /tool="antismash"
     gene            17268..18731
                     /locus_tag="HT134_RS32980"
                     /old_locus_tag="HT134_32960"
     CDS             17268..18731
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012546.5"
                     /locus_tag="HT134_RS32980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32960"
                     /product="S9 family peptidase"
                     /protein_id="WP_175604386.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 7.6e-09, bitscore:
                     29.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRVLLAGLAAVLWCLLAAPGARAAAATGAPAVPGDLTAAEVTFR
                     GDGGLVMHGTVLSPAHGGGGKRPGIVLIHGAGTGTPRTKLMGEAVEFARRGLSVLVYDK
                     RSVGYSLFERSYAQLAGDALGAVAALRRQPGVDPAKVGVWGLSEGGWVAPMAAARSRDV
                     AFVVLVGANSQQPLLQQAWAVHAGLRAAGVRGRLVDGTEPDLYRVLADGELFPEPYYDP
                     APTIAAVRCPVLAVWGVHDLLTPARESGAGFAEALRRGGNEHLTVRYFADADHAAHLTP
                     DRGVTRLPELAPGYADLVGSWVTDVTSGRPPASGASGPEPVQATPTVPVPPVEWWEAAD
                     VQAGALVVMLAGFAAYPLGALVRRVRARSAPAGAGVSRRPVSAAARLLSAGGLTVVLGS
                     FGYVMYAVMTGAKLGSPGPLVAGRPVVWLALQALAVACVVATAVTGLAWWRRRAGVAAG
                     ERVRLAALMAGGLVLVPWGLYWGLLLPGL"
     gene            18782..19138
                     /locus_tag="HT134_RS32985"
                     /old_locus_tag="HT134_32965"
     CDS             18782..19138
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017593009.1"
                     /locus_tag="HT134_RS32985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32965"
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="WP_175604387.1"
                     /transl_table=11
                     /translation="MGVSVEEFLDLVDKLPEVRRDRMATWVSFKVRGKGFGYLWEETET
                     VGVKATVEEQIALVAERPEVFEPQFTAGRFGWVVIRLDRIDYDELFELVAEAWCLTAPK
                     TLVTAFESAHHIGG"
     gene            19149..19640
                     /locus_tag="HT134_RS32990"
                     /old_locus_tag="HT134_32970"
     CDS             19149..19640
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012887392.1"
                     /locus_tag="HT134_RS32990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_32970"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_175604388.1"
                     /transl_table=11
                     /translation="MLTTNIRLREWREDDAPAVLAAFQDPDLSRQAPWPVVTPQDALGW
                     IASWDGVGHAFAVTLAGRVVGNVAVARIDAHANGWVSYWTVREARGRGVAPAAVEELAR
                     WAFRERGLFRLELGHRVDNPASCRVAVKAGFRAEGIERGKLAHDGVRHDVERHARLATD
                     "
     gene            19753..20130
                     /locus_tag="HT134_RS32995"
                     /old_locus_tag="HT134_32975"
     CDS             19753..20130
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS32995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HT134_32975"
                     /product="hypothetical protein"
                     /protein_id="WP_175604389.1"
                     /transl_table=11
                     /translation="MDSESLAAAGLLAAMSRAAASLAELRHPFVRSEPFCYFFPPAGVR
                     AGTAFTLPDGREVSFTVSIAASGGAFHVDGAASAEGEALLDLPARTASGIGDGIAVLDD
                     YAAELVSSAARLIDQLLDELV"
     misc_feature    19825..19827
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    20163..20177
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.65"
                     /tool="antismash"
ORIGIN
        1 gggcgggacg gtgatctccg tcgaggtgcg cggcgccgtg ggcgacgtgc tccggggaca
       61 ggtggagctc gcctgcgacc tggccgccac gtacgacatg aggcccaggt agggaagccc
      121 gtcccggaac ctgggccctg ccgccgcccg agccgctacg cggagccggg accgcccgga
      181 gcgatcccgc ccgaggccgg gaggaggtcg gcgaagagcg tgtccctgga ggacgccgcg
      241 gcgtcctcgg ccgccgtgac cgccgtcaga atctcgtggg ccaggctcgc cgcgtcgagc
      301 cgtctccggc tgcgcgccga gatctccagc cgcacgaggg tgccgagcgc gtcggtgacg
      361 gccgtgatcc cgccgtcgtc ggcccggccg gagaactcgg cggcactcca ttcctccacc
      421 ctcgcctccg cccgcgcggc ggcggagatg agcgcgtcca gccgcgcctg cgcctcctcg
      481 aactccttga tcccgtcaga gccttccacc gcagagcctt ccaccgctca gtctcctcgc
      541 agcacgttgc ggatgtatcc gtcgagcggg tcggcggcgt cggcgcccgt ggtgctccgg
      601 cccgggcccg agagctcctg catgacctcc gtcagccgat cgcccatcgt ccggtgagcc
      661 gcggcgatcg cctcctggac ggcgtgcgcg agctggacgt ggtcgaggcc gcgcaggccg
      721 cgcggatcga tcgacagccc gcgcaggcgc ccgctgccgc tcacctcggc gcgcaccacc
      781 cctgacgggt cggtgcccgc cagccgctcc tccgccagcc cggtcaacgc cccgttcagg
      841 gcgcgggtcc agtcgtcggc ctggcgcagc aggttgacga cgtcctccgg cccgttcagg
      901 gcggacgcct cgacgtccct catgaggcct tcttggaggg tgacttgccc ttggccggtt
      961 cgggctcgtt catggggacc cagtactcgt ccaccaggcg ggggtcggcg atcgcgtcgg
     1021 tgaggtgcag gtcgcgcgcg ccccgcgacg ggtcgccgga ccggtagaag gcgcctctca
     1081 ggtcgttgag cttcagctcc agcttgttga gctcgctctc gtacttgttg tagacgtcgg
     1141 cgaactgctt gacgaggttg ccggccgcgc tcatgaacag gccgacctgg gtcatcaggg
     1201 cgaccctgcc gaccgggtgc gtgctcatcg tggccaccgc gcgcaggatg ggcgccgagg
     1261 tggcgtacaa cccgaacacc gacaggtcgt actccatcac ctccttgtac tggctgtgca
     1321 tggtgctgct catcgcgccg gagatcttgc cgagctggcc gtacaggccg ttgatgttga
     1381 accggacgta ctgctggagg gtctgctgcg ccacgccctt ccagtagggg gtgatgtcgt
     1441 cgaagaacga gcgccataag tcggaccggc tgccctccag cgccccggcc atgtccttcc
     1501 acagctcgcg tcgcgcgtag aacaggaacg ggttgcccat gttgagggtg gccaccacgt
     1561 cgagcgcgag cgccgccgcg ccgagccccg agaccgccat ggcggcccgg ttgttctggc
     1621 gcagcgggtt cagcccctgg atcagccgcc gatagaagcc ggggtcggta cgcggcgtgg
     1681 ggctgaccgt gatggtccgc tgcacggtgc cgttggcgtt ggcgatgtgc agttgccggt
     1741 cgcccgtggg cgcggtctga ccgggcagga tcagcttcgg cggttcgccc gacgaactcg
     1801 acggaaccgt catcgcggat tcctcctcat gcgggggtgc tgtggtggtc ggcggcgtgg
     1861 tagttgtcgg cggccttgac gatcttgccg ccgtcggtgc gcaacaaccc ggacaggatg
     1921 ccggcgcagt cggcccaggt gtcggagacg gtgttgaacc ggttgacgaa cagcaacccg
     1981 gctatgggca cgccggccat ggggatgagc tgccagccct cgaagcgggg cgtccagtgc
     2041 ttgacggtct ccacgccggt ggccgagctg tccatggtgc cggcgaactt ccgtatgaac
     2101 gcctcgttga cgtcgtagcc gttggggctg cccgtgtcgt ccggcggcgg cgcctgccgg
     2161 gtggacacgg ccagtgccgg ctgcgcctgg ccggcggaca cggcccgtgc cggctgcgcc
     2221 cgcaggctct gcgggaggca ggcaggcggc gggcaggcgg gggtgtgcgg gcacgggctc
     2281 accactgagg gcgaaccagc cgcgaacgac aaggcatgat catctgacac gggctctttg
     2341 tatcatcacc gttccgggcg gctggagccg ccgtggccga tccggcgcgg gtgaacggaa
     2401 gataactctc gcgttactga cacagcctcg cgcggtgcgt aaattgcggc tggtgtgatc
     2461 actgatcact gatcgcccgt cacttcctgt ttccaggatc tcctctccaa agggtcacat
     2521 gacgacgcac ctcccctcct tccccgccgt gaacgagaac ccgctcgaca cctgcctccg
     2581 gctgcgcgag atcgcccccg tggtcgaggt ggagttcccg ggcggcgtgc ccgcctacct
     2641 tgcgctgacc cacaaggccg tgcgggagat cctcgccggg gacaacaaga ccttcctgcg
     2701 ggacccccgc cactggcccg cgctgtacga cggatcgatt cccgaggact ggccgctgcg
     2761 cgccatcgtc cagggcggtc acctgtccac catggacggc ggcgaccaca ggcggctgcg
     2821 cggcctggtc ggcagggcgt tcacgccggc ccgggtgcag gccctggagc cgcggatcca
     2881 gcagatcatc gacggcctgc tggacgacgt cgtggccgcc ggcgacggcg tcgacctggt
     2941 gcccgccttc accgaggcgc tgccgatgtg ggtgatctgc gagctgttcg gcatccccgc
     3001 cgaggaccgg ctgcgcctgc gcaactggac cgccacgctg ctggcgcaca ccaccccgcc
     3061 ggaggtggcg ttcgcgacgc agaacgaact gcaggccttc ctgcacgagc tggtggagcg
     3121 caagcagcgc gaaccgggcg acgacctcac ctcgggcctg gtgcaggccc gcgacgaggg
     3181 cgaccggctg accaccgacg aactcgtcgg cgtgctgtgg ctcatgctcg tcgccggcca
     3241 cgagacgacc gtgcacctgc tcgggtacgc cgtcgtggcc ctggcccgca accccggcca
     3301 gctccggctg gccatggccg aggaccgctg ggccgacgtg gtcgaggaga ccctgcgcta
     3361 ccgccattcg gtgatgatga ccagcttccg tttcacggcg gaggacgtga ccgttgcggg
     3421 ggtgcgcatc cccaagggca acgcggtggg cgtggtctac caggcgagcg gcgtcgatcc
     3481 ggcggagtac ggcgacagcg ccgaccggtt cgacatcacc cgtgagcaga ccgggcacct
     3541 cggcttcggc cacggcccgc gctactgcat cggggcgccg ctggcccggc tggagagcag
     3601 gctggctctc gcctcgctgt accggcggct gccgcggctg agcctcgcga tcgaccccga
     3661 cgacatcgcg tactccccgt cgttcttcac gatcggcccg ctgtcgctgc cggtggacct
     3721 cggtctcacc gcgtcctgac gttttgccgg tcgttggcat cggagcgccg gcgacagggg
     3781 tacgtcctcc cccatggggc gatcttcgca gccccggagg ggaggacggt catgtacgcg
     3841 acggtacggc ggtacgaggg agtcaccgat cccgccgagg cggcacgcct ggtcaacgag
     3901 gggttcgtgc cgctcctgcg cgacgtcccc gggttcgtgg cctactactg ggtcgacgcg
     3961 ggggacggcg tgatgctgtc caccagtgtc ttcgaggatg aggccggggc cgaggagtcc
     4021 accaagcggg ccgccgagtt cgtgcgggag agcctctcgt ccctgctgcc gaacgctcct
     4081 caggtcacgg ccggcgaggt cgtggcgacc gggtgacggc cggctgccgc tcaggcgact
     4141 gatcaggcgg ctggtcaggg cggctggtca gggcggctgg tcagggtggc tggtcagggt
     4201 ggctggtcag gcggcgccga agtccgcggc gtggtcgcgg gcccactgcc cgtacgtccg
     4261 ggcgggccgg ccggtgacct tcgcgatcgt gtccgtgggc ggcaggggcc ggtccacggc
     4321 ggcggccgac tcgcggatca ccgcctcggc gacctgcggc gtcgtccagg cgccgagctc
     4381 ggcccggtac tcctccaggt cctggacgtc gaagcggacc gggcggccga cggcctcgcc
     4441 gatcagctcg gcctgacgcc tccgggtgag cagttccggc ccggtcagcg tgtacgccgc
     4501 gccctcgtgc cccggctcgg tcaaggcgcg tacggcgacc gccgcgatgt cggcctcgtg
     4561 cacgggcgcc gagcgggagt ccgggaacgg gtcccgtacc actccctcgt cccggaccga
     4621 gcgggcccac tgcagggtgt tggtggcgaa cccgcccggc cgcaggaacg tccaggcgac
     4681 gccggagcgg gtcacggcct gctccgcgtc gccgtgcatg cggctgatcg cgtcggccga
     4741 ggcgggatcg tggagcaccc cggacagcag gacgatgtgc tccaccccgg cggacgccgc
     4801 ggcggcgacg aagccgtcca caccgcgcgg ctcggcgtac aggaagacct tgccgacgcc
     4861 cgtgagcgcc ttgccgaacg tggcggggtc ggcgaggtcg cagagcaccg cctccacccc
     4921 ggcgggcacg cgggccgcgc ccgggtcgcg gccggccgcg cggaccggct ctcccgcgtc
     4981 gagaagctgt cgtacgaggc tgcgcgcgac gtgcccgcgc gctccggtga ccagaatcgt
     5041 catgtgacca gcctggccgc ggccaggaga ggccgggtag gcacccgtgg gcctgggact
     5101 cgcagtacca ggccatgatg gaggacgatg aacagggagg aactgggcag cttcctgcgc
     5161 agcaggcgcg agcgggtcag ccccggcgag gtcgggctcg ctcccggcgg ccggcgccag
     5221 acgccggggc tgcggcgcga ggaggtcgcg ctgctggccg ggatctcggt cgactactac
     5281 atccggctgg agcaagggcg cgggccgcag ccgtccgcgc aggtgctcgc cgcgctcagc
     5341 cgtacgctgc ggctgagcgg cgacgagcac gactacctgc tccgcatggg cgaccaggcg
     5401 ccggctccgg cgggctcctc gccggaggtg cccgcgaacg cgctgcgcct cctggaacgc
     5461 ctggacgagg tccccgcgat gatcgtcaac acccgcggcg acctgctggc ctggaacgag
     5521 atgctggtcg cgctcatcgg cgacccggca gacataccgc gccgggagcg gaacacgctg
     5581 cgatggctgt tcggcaccga gccgaacctg ccgcacaacc gggtcgagct cgcccgccag
     5641 gccgtcgccg acctgcgggc cagcggccgc tacccggacg acccgggtgt gcggcagctc
     5701 gtggacgagc tgacctcgac gagccggctg ttcgccgaac tgtgggcggc gcgggaggtg
     5761 gaggtgcagc ggaccatgac gaagaggacc acgcatcccg tgctgggcga gatggagctc
     5821 gactgcgagg tcctgtccct gcccggcggc gaccatcgcg tcatcctcta caccgccgcc
     5881 ccgggcacgc ccacccatga cgcgctcaag cggctgcgat catcacgcgg ccggccgccc
     5941 aggcacgcgg gatgcgtcat ccccaccgga cctgccgaca ggtgaccggc ggcctctcgc
     6001 cggcgggtga gcgctgtcag gcgtatcgct ccagccaggc cacgatgtgg tcgacgtagc
     6061 tgtcgacgta cctcagcggc ttgccgccga gttcgaggac cgcgacgagg tggtccacgc
     6121 cgaaggtgcg atcccagacg cgggcccgcc ggtaggtctc gcggtcgacg gcctggcgga
     6181 ggtggtccca gccgtgccag gccatgaagg cggcgtcgat cgcgggatcg aacaggtggg
     6241 cccggtccca gtcgaggacg ccgatcagcc ggccgtcctc gccccagtgg acgttgctcc
     6301 ccacgaggtc gccgtggacg agcgtgtcgg ggaccggctc cagggccgtc gcctccgcca
     6361 ggcgccgccg gccctcctcg cgccacctgt cggggaagcg cgggatgacc tcctcggcca
     6421 ggatcgccgc ccagttgtcg cggccctcgt gctcgcgcgg cgcgggcagc agggcgcgca
     6481 gctccggcgt gacggggagc tcccggatgg cgctcagcag ggcgccggtt cccgcggggt
     6541 cgcccacgcc ctcggggtgc ccggcgccgt cgatccacga cacggcgacg gccgcccgct
     6601 cctcgaacca cgtcaccggg gtcagcggct cggggacggc gaaggggagc ccggcggcgg
     6661 cgatcagacg cagcacctcg gtacggcgtg gcagggcctc ggcgccggtg gggcgccggc
     6721 tgacgcgcac ggcggcgaca ccgggcagca ggacgacgtc gtggatgccg ccccggacga
     6781 accgcgccga gtcgaggcgg gcccccggca cgagcgcgtc ggccatcgcc agcaggtcgt
     6841 cgggtacccg gtcggtcatc tcgttcggct gctctcggtc gtgcggtcgg tgcgggcggt
     6901 cagagggtgt ggccgccgag gtcgcggacg accccggcga aggcgcggac gaagtgcagc
     6961 tccgccgcga gggtcaggac gacctcgatg tcggcgacgc gctgacaccc ggcgaacccc
     7021 ttctcagcgg acgtcgagtg cgctgacagc gtggttcaga gaactctgat ccgtcaacag
     7081 agatcctcct cacgcatcgg gacatgactg tgaacaccga gatccgggcc ggtgtgccgg
     7141 ccctcggcct tgccctgacc accgccggca ccgccgccgc gggcgtggcg gcgtggctgg
     7201 cgcaggcccg gccgtcccgc ctgatcggcg gtggttcctg gtcgccggac caggcgaccg
     7261 aggtggcgct cggccggtcg ttcgacgtgg tgatccacct gcacaaggtc acggccgccc
     7321 ggctcctgcc gtgacccgcg acggcccgtg acccgcgagg gtccgtgacg ggtggcagcc
     7381 ggacgacggc ggccgggagg ccggcgtcgt ccggtccctg gagtcgggga gggcggcctc
     7441 accgagccgg agagagaagg ctcatcgagc cggcgagaga agcctcatcg agcgggagag
     7501 agcaggctca ctgaggggcg tcgaaggtcc acacggcgtg cgcgccgggg cccacggcga
     7561 gggtcgagcg gccgatccgc tcctcggtca tgtacgccag cgacttgttg agcacgaagt
     7621 cgacccgctt caggccggcc tgctcgcgcg gaacggagtc gaggtggatc cgggtgccgc
     7681 cgcccgtcgc gacgacgccg ccgttggcga gggactggac ggtgaacccg ccggcgcgca
     7741 gcagcggcac catggtggcg aggtcgcggg ccgggacccc catgcggatg gcggtgatgt
     7801 cgcgcatcag gcggtcgcgg tagtcgtcgg gcaggtagcg ctcgcggccg acgtcgccgg
     7861 ggaagctctc cggctcggtc ttgctgcgcg ggtcggcgaa gtactccggc aggtactcca
     7921 tcgcccaggg gtcgaaggcc tcgtactggt cgctgaaggt gcggatggtg tcgaaccacg
     7981 gcaccttgac gccgtcgccg aagtcgcgcg tctggcggta cgggaccggg gtgatcccct
     8041 gcgccttcag ccgctcgccc acggtggcga ggtcgccggc gcgctcggcc gagacggcca
     8101 tgccggcgga gccgaactcg gcgtcctggc cgggcaggtc gccgaccgag aacagttcga
     8161 ggtaggtctc ccggcccttc aggtagcggc ccttccaggt catcccgccg ccggtcgtgg
     8221 tgcggacctc gaagttggcg aacttcttca ggtactcgga gttctcgacc gcgtcggcgg
     8281 tctccttgtc cacaacgctg taggcgtggt tgtagaacag cagctgacgg tcggtcttcg
     8341 gctgggcctc gtcggccgtg gccgcgctcg cgcctcccgc gaccgcaccg gtcagcgcga
     8401 cggtgaacgc cgcggtgagc acggtgatcg tccgtaaggt tcggttaatc agcatgttcg
     8461 tgatcttagg caggcagtga tcaacaccac tggggatttg acaatcccct aacatcgcgg
     8521 ttcgaaacgg cgcaggaacc cgtcgtcgag gacgaggaag cgggtgatgc cccgcacccg
     8581 gtcgccggcg agggtgagca cgatcactcc cgcgggctcc ccgccgaggc ggcaggtgaa
     8641 ggccggctgc ccgttcgccc gcgtgggcac cagcagcacg ggcaggtccg cgctccaggc
     8701 ggtgctcgcc cgtaggaacg aggcgatcgc cggcacgccg tggtactcgt gcggcgccgg
     8761 aggcatggcc agccacgcgt cgtcggtgag cagggtgacc agcgcgtcga tgtcgtcggc
     8821 ggtgaaggcg tcggcgaagc ggcggaccag ctcgcgctcc cgcgccgatc ccggcgcggg
     8881 cgcctcgggg tggcgcccgc cgccccgctc cggttgtcgg gcgagcgagg tgcgggcccg
     8941 ttgcagcagt cccttgaccg cggtcggcgt gacgccgagc atcggcgcga cctcgccggg
     9001 cgggtagccg agcacgtccc ggagcacgag gacggcggcc tgccggggcg ggagtcgctg
     9061 gagcgcggcg acgaacgcca gctcgaccgc ctcgcgcgcc gtgcagcgcg cctcgggacc
     9121 gggcgccgcg tcgggcacca gcagcgtgtc cgggtacggc tgcagccacg gcacgtctcc
     9181 gtgacggctc ggcggcggcg gctcgaacgg cggcttcggc tccggcggga cgcgccgccc
     9241 gcggtcgcgc agcgcgttca ggcagcggtt ggtggcgatg cggtacagcc acgaccgcaa
     9301 cgacgagcgg ccctcgaagc cgtccaggcc gcgccaggcg gcgaggagcg tctcctgcag
     9361 gacgtcctcg gcgtccgtca gcgatcccag caggcggtag cagtgcagca gcagctcgcg
     9421 ccggtacgcc gcgacctgct cctcgaacgc gatttccgcc acgaccgttc cgttccgcgg
     9481 gcttccggtg tcgtaacggg cgacaacgga aggagacacc atgtccggct cagcattgca
     9541 gatcgcgctg gcccaccacc gcgcgtggac cggcaaggac ctcgacctgg cgatgagcta
     9601 cctcgccgac gacgtcgtgt gcgacgcccc ggcggggcgg ctcacgggcg tcgaggcgta
     9661 ccgggagttc ctggggccgt tcgccgagca cctgctcgtc agggcggagc tgatcgccgc
     9721 gttcggggac gacgagacgg ctttgatcat gtacgacgcc gagaccgtcc cggccaggag
     9781 cgcgccggcg gccgaatgcg tcacggtgcg ggacgggagg atcgtccaca accggttcgt
     9841 gttcgaccgg accccgttcg aggagttccg ccgtcgccag gagcagtccc gggcgtgagc
     9901 cgcccgccgc ccgggctcgg gccgttccac ggctccggct ccgggcggcg ggagtcaatt
     9961 gatcttgacc ggggtactgg ccggtaacga cgatcggggg atgcgcctgc ctcgtgtgaa
    10021 acccgagcac gctccccagc ggctcggcga cggcaccgtc cggctcggcg gggccctgta
    10081 cggcatcgcc tccgagatcg cggacgccga cggctgggcc tggacggcgc tgagcctcat
    10141 ggacggcacg cgtccccccg cgcggatcgc cgccgagctg cgcgcccgcc accccgtgct
    10201 gacgtgcgag gaggccgagg acatcgtcgc cacccttgtg tcgtccggcc acgtggagga
    10261 cgccgcgccc gagccctgcc cggagctgac cgagcgggag aaggagcgcc acagccgcac
    10321 cagggactac ttccgctggg tcgacctcac cccgcgcgac cacggctggg agccgcaggt
    10381 gcggatcaag aacgcccggg tggtggtgct cggcctgggc gggaccggca gccacgtggc
    10441 ctggacgctg gccgccgccg gcgtcggtcg gctgcacctg gtggatcccg acgtcgtgga
    10501 gctgtccaac ctgaaccggc agatcctcta caccgagccg gacgtcggcc ggctcaaggc
    10561 ggaggtggcg ctcgaccggc tgcgccaggt caactccgag atcggcatca ccgccgaggc
    10621 ggccgcggtg gacggccccg ggcggctggc ccgcctgatc gacgggttcg acgtcctcgc
    10681 gctctgcgcc gaccgccccc gggggccgta cgggatccag agctgggcca accgggtgtg
    10741 cgccgaggcg gggatcccgt gggtgagcgg cgggtacaac gggccgctcg tcagcgtggg
    10801 cgtcttcggc ccgggcggtc cctgctacga gtgcgtgcgc gccggcatcc cgtcgcggcc
    10861 cggcgcggac tacgcctggc ccggcgtgac cggggcctcg gccgggctgt ccggccacct
    10921 ggtggcgcac gacgtcctgg ccctggtgac cggggtcatg tccacgccgc cgggctactt
    10981 ccacggggtg atgctgctgg acccggacgg ccacgtgtac gcccgccacc cctcgcgtcc
    11041 cgattgcgac atctgttctt gatcaaggag cgggaagacc gtacgttcgc ggttaccgtt
    11101 ccccactcac ctcggtaagg aggagtgtca tgagcaacac ccccgccccg gaagcgcagc
    11161 aggagcggaa gccgcgcaag aggatcgtcg tccgccggct cgacaaggtc gggccgaccg
    11221 cgtgggcgcc cagccagggc aactcgaact gacccgcgtg cgggcggggg gtggcccgcc
    11281 cgcacgccgg gaggcctgat gagtcacgtc gagaggcccg ccgggcctgt tcgggaggcc
    11341 tgatgagtga cgttctgaac cgtctgcgca cggtccccgc ccaggtgatg gacgccgccg
    11401 agtacggggc cgacttcgcc ggggcgctcg cggccacgag cggcgtcgtg tggaagctcg
    11461 aacgggcgca gcatttcgac gagggagacc tgcccagcta cctggcgatg gtcgagggcg
    11521 actgggaccg cgcgatggag ctggccgagc ggatgcgccc cggcttccgc gacgacaatc
    11581 ccgcccggct cgacttccgg cggatcaggg tggtggagga gccgttcacc ccgtatctcc
    11641 gctgggagct cgcgctgctc gccatgcggg ccgaggaggg ggagaacggc cgggtggtgc
    11701 cggtctcggc ggtgcgcccg tacgaggacg gcggccccgt gccggagctg gtgctgctcc
    11761 gtccgaccct gctctacgag gtcctgtacg acgaggcggg caggcacgtc ggggcccgcc
    11821 ggatcaccga cccgcgggtc gtcgagccgt gcgtgccggt cctggccggc ctgttcgagc
    11881 gcggcgagga cctgcgcgcg tactgggtca gaaagcgtac ggcctagggc cggcgatcgg
    11941 ctcagagatc ggctcagaga tcggctcaga ggtcggcgag gaagccgagc gccgtcgccc
    12001 aggcgcgctc ggcggactcg gggtcgtggt cgggcaggtc cgggtcggtg aacaggtggc
    12061 ccgcgcccgg gtaccggaac acctccacgt cggccccggc ccggcgcatc agcaggtacc
    12121 acgtgttctg ccagtcgacc ggctcgtacg tgtcggggtc ggcgacgtgg agctgcacgg
    12181 gcaggtcgtc caggaacgct ccctcgggca ggtcggacgt gccgtgcatc agcagcaggc
    12241 cccgggcgtt ctcgtcggcc agggcgaggt tctgcgcgag cgcgccgccg agggagagcc
    12301 ccgcgtacac gacgccctgc ccggacaggg gagcggcggc ggccacggcc cgcttcagca
    12361 gctcgtcgcg gccgagctcg tccttgatcg cgatggcctc ctcgggcgtg ccgacgacgc
    12421 gcccgtcgta caggtcgggg acgtgcacct cgtggccggc cgcgcgcagc cgcccggcgg
    12481 cctggtggac ggcgggccgc aggccgtact gggagtgcag gagcaggatc cgtgccatgg
    12541 ggccaagtct aggagggccc ctcgtcgctc ccgtgccgca caatgtccgg atgatccgtc
    12601 cacgcttatc cgccctgtcc ctggtcctgc tcctgacgcc ggtcgccggt tgcgcgtccg
    12661 ccgacctggg gatcttcgat cggaccggtt acacgatgac cagccaggcc atggagccca
    12721 cgatcaagca cggcgcccac atgtcggtgc ggcgggtcgg cgacgcgtac gtcccgcgcg
    12781 tcggcgacgt catcgtctac cgcgagccgg agggctggtc ggtgggcacc cccgaccccg
    12841 agaggaccta tgtctcgcgg gtcatcggcg tgccgggcag cacggtgaag tgctgcgact
    12901 cccacgggcg gctggagctg gacggcaagg cgctggacga gccgtacatc gccaaacccc
    12961 cggcctccga cctggacttc gacgtgcagg tgccgcgcga ccggatatgg atcatgagcg
    13021 acaaccggca ttccgccctg gactcccgct cccatcagga cgccccgggc accgggacga
    13081 tcagcgtctc cgacgtcgtc ggggtggtcg aggatccgcg ggggtcctag gcgccggccg
    13141 gctccaggaa ctccaggcgg ttgccgtgcg ggtcctcgct gtagaagcgg cgcatgcccg
    13201 ggaagtcgtc gtcgaacgtg accgggtacc cggcggcgcg cagccgctcg gcccacgcgt
    13261 cgaggccgga gacgagcagc ccggggtggg ccttgcgggc cgggcggaag tcggcctcga
    13321 cgcccaggtg cagctcgatg ccgtggccgc ggaaccagca gccgccccgc gccgccagca
    13381 ccgggggctt ggggatctcg gccaggccga ggacgccctc gtagaagtcg cgaagggcct
    13441 gctcgctccc gggcgggcag gccagctgga cgtggtgcag catcggggct cctctcggta
    13501 tcttgatgtc aagttacatc agcggaggtc gccagctgct cgcgcagcag atcgtgccgg
    13561 aagtagtaca tgccaccgac cttgcggaga accccgcgcc ggtgcgcgtc ctccaggaac
    13621 gccaggacgc gccagggcag gacgccccgg agcgtgaaga acacgcgggc gatgaggaac
    13681 cggacccagg agttctccag cagggtcacg aggacgaggg tgaggaccgc cgcgaggccg
    13741 agcgaccacg gcgaggaggg cccggtcgtg acgaggagcg tgagagcgaa gtcgatgacc
    13801 gccgcgatga aggtgatcac gcctctgctc aggacgacga acagccagag cgaggtcacg
    13861 agggccagcc cggccgcctg tccggccgtg gacccctgca tggcgctgag gtaccagtgg
    13921 acggcggcga agaggaccgc ggccggacct cccgcggtga gcagggtcat ggggctcagg
    13981 aacacggggg agagcgagtg gtcccccgcg aagacgtaga ccaggacgac gagggcgatc
    14041 gtcgtgccga gcacgagccc cacgacgggc gacgcggcga cggcgaacgc cacggcggcg
    14101 gccaggccgg ccagcgagct gaagatcagg ttctcggccg gggacgggac ctcgtcggtc
    14161 agcgactccc gggagatccc gtgcttgggg aagcggcggg cgagatggga cagccacgag
    14221 tggacgtcgc gatggcccca ggagggtccg ggcaggtcgt cgcggccggc gtagacggtg
    14281 ggcaccaggt gcgcgagcag atgggcctcg acggcgtgcc gggtcctgaa cgtgagcagc
    14341 aggtcggggt cctcggcgcc ttccgcgtac gtcatgcgcg ccagcgacag ggcgagcggc
    14401 gtggacaggc cgcgcgccgt ctcgctgtcg ggcgcgcggg tcagctcccc gaacaccctc
    14461 tcccaccgcg gaagccgcgc gggtttcgtg gtgatggtca ggtactcgcg gatcgcctcc
    14521 gcgtccagcg ggttgagctc cacgacggcg gcggccgtga gcacgtccgc gtcgggatgg
    14581 tcgatggtgg ccgcgtactc gtggctgcgg ctggtcagga tgacgggcga cgtggcgccg
    14641 aaggtggcgt tgatctctct cagcgtccgg gtgcggagcg gctcgggcat ctcgtcgagg
    14701 ccgtcgagga tcggcagcag ccgatccagg ctcacggact cgtggaagcc gtagtccgcg
    14761 cgcaggcgcg cgtagatcca cgtcgtgagc cgtttgccgt cggccggctc ccgggtggac
    14821 agccgtaaga tcaccggtac gggagagtcg tcgtcccggc gggccagcca ggcgagggcg
    14881 aaacgcatga tcagcgatga cttgcccgcg ccgggctcgc cgagtatcac gaggcgtggg
    14941 gctcggagcc tggtccggac gatgtcgtag agctcgtcga gggagccgtc gaggtcgatc
    15001 ggctcgtcgc cgccgtggat gacgcgccag tggtcgctca ccggtgggcc gagggtccgc
    15061 caggagaccg ggagcggcct cgggtcgagc agccgctggc gcagctcctc cgactcccag
    15121 acctggcgga ctctggcggc cagccgtgcg aggcgctccg ccatgacctc ggcgctcacc
    15181 tcctgatcgt cgggatcggc ggcggcggct gtggcggctc ggccccgcag ccagcgcagc
    15241 agcgcgaccg agcctccgat gagcgcgacg acggcgctga cgatgctcgc ccactggtcg
    15301 gcgttctccc agccttcgga caggaagaac caccccagcg tgacaccgcc gaccgggacg
    15361 aggaagagag cgaggatgag tgcccagtac cagacgcgaa ggcccgagcg ttggcgcatc
    15421 aggccagcat gccgcccggg cgcccgccgg caaaatcagc cggctcggcc ctccgcgccg
    15481 agggcggcgg cgagttcgtc gggggtgagg cggcgggagg cgacgtagta gagcacggag
    15541 ccggccggca gctcggtccg ccagtcgggg ttcacgagca gctcgtcgcc ggtgcgggcg
    15601 gccagcagcg tggccccgca gcggcggccg agcgagacct ggcagcggtc caccagcacc
    15661 ggccccaccg actcgggcag ccgcaccgag taggtctcgg cgtcgccgtg ggtcatgagc
    15721 tgcgtgtaca cctcggcgat gcccgggtcg cgcagctcct cagtgatcat gtacgggctg
    15781 tgccactgga cgcagcgcag cgtgtcccgg acgtagcgga gctggcggac ccgcgagacg
    15841 tcgcgcagcg ccacgacgag gtgcgccccg tgggccacgt ggtcggcggt gatcgcgacg
    15901 gccagcgcct cgttgtcgtc gcgggcgtcg acgaggacgc tgtgcgcccg gtggacgccg
    15961 gcccggagca gcaccttgtc gtcggtcagg tcgccgcgca cgaacgtcac ctcgcgctcc
    16021 ggcatggggt gggtctgcac ctcgtcccac gcgcagagca cgatgcggca cgacccgtcc
    16081 gcggccagct cgtccaccat ctgctcggta cggccgggcg tgtagccgag cagcacgatg
    16141 tgaccggaca tgtccacggt gacggcacct cgcatccttc gtcccttggc gcgttccagg
    16201 ctcgacgcga acctcgtgaa gacggtcgtc agcgtcgcga tgccgccggc gatgacgtac
    16261 gcgcccacgg cgtgcccggc ggcggtctcc gggtacaggt cgccgtagcc cacggtggag
    16321 gcggtgacga cgaagtacca ccagtagttg cccggggcca cgatctcgct gccggccggt
    16381 tccgcgagcg ccatcagcgg ccagctcgtc aggaacacca gcgtgaagac gaggaccggg
    16441 gtccaccagg tcccgaggag gacgagccgg gccagcatgc gggcgaggaa gaggggcacg
    16501 cttgtcctcc tgcctgacgc cgctgttctg cggtcaccat aactggacaa accccacaaa
    16561 gcagcccctc ggatcgcagc agcctcaggc gtcaggggtc ccttcggggt cttccgaggc
    16621 cgtggcgggg aaggcccaga ggcgtaggta cagcgggcgg gcgcccggcg gggcctcctc
    16681 gcgtgagtgg ctgtgcctga gcaggagctc catgtagccc tcgaagaacg cctcgaactc
    16741 ctcgtccgtc atccagccga gcccccgtga cgccttcacc cgcgcggggt cgcgttcgta
    16801 cagccggggc agcccctcca ggagccgcag gtcctcctcc aggcccaggc ggtggaactc
    16861 ggccaggatc gggcggtcct ccggcgccag ccggtcgggt gcgggaaggc gcatgtcgcg
    16921 tggcgccggg gccttgcgcc accagcgctc cctgccggtc gatcgctccg gtatctcctc
    16981 gatgaagccg tacttctcca gctggcgcag gtggtagctg gtcgtgccgg tcttcgcgcc
    17041 gagcagctcg ccgagcgtgg tggaggtggc cgggccgtgg acgcccaggt ggcgcagcat
    17101 gaggcggcgc atcgggtggg ccagcgcctt gagccgggcc gggtcgtcga gcaggaagga
    17161 ctcgggggag gcggcctcat ccgtcatgag gaggagtcta gtcccgcaga gggatttctg
    17221 ccgagatctg tttgccgaga cttgtctgca aagtactctc ggcagacatg agacgtgttc
    17281 tgctggccgg actggccgcc gttctgtggt gtctgctcgc cgcgcccgga gcccgggccg
    17341 ccgcggcgac cggggctccg gccgtacccg gtgatctgac ggcggccgag gtcaccttcc
    17401 gcggcgacgg agggctcgtc atgcacggga ccgtcctgtc gcccgcccac ggcggcggcg
    17461 ggaagcggcc cgggatcgtg ctgatccacg gagccggcac ggggacgccc cggaccaagc
    17521 tcatgggcga ggccgtcgag ttcgcccgca gggggttgtc ggtgctcgtg tacgacaagc
    17581 ggtccgtcgg ctactccctc ttcgagcgct cgtacgcgca gctcgccggc gacgcgctgg
    17641 gggccgtggc ggcgctgcgc cggcagccgg gcgtggaccc ggcgaaggtg ggcgtctggg
    17701 ggctcagcga gggcggctgg gtggcgccga tggccgccgc ccggtcccgc gacgtcgcct
    17761 tcgtcgtgct cgtcggcgcc aacagccagc agccgctgct ccagcaggcg tgggccgtgc
    17821 acgccggcct gcgcgccgcc ggtgtcaggg gacggctggt ggacggcacg gagcccgacc
    17881 tgtaccgggt gctggccgac ggcgagctct tccccgagcc gtactacgac cccgccccca
    17941 ccatcgccgc cgtgcgctgc ccggtgctcg ccgtctgggg cgttcacgac ctgctgaccc
    18001 ccgcccggga gagcggcgcg ggcttcgccg aggcgctgcg ccgcggcggc aacgagcacc
    18061 tcaccgtccg ctacttcgcg gacgccgacc acgccgccca cctgaccccc gaccgcggcg
    18121 tcacccggct gcccgagctg gcccccggct acgccgacct ggtcggctcc tgggtgacgg
    18181 acgtgacctc cggccgtccg cccgcgagcg gcgcgtccgg gccggagccg gtgcaggcga
    18241 ccccgaccgt gccggtgccg ccggtggagt ggtgggaggc cgccgacgtg caggccggag
    18301 cgctggtggt gatgctcgcc gggttcgccg cgtacccgct gggcgccctg gtccggcggg
    18361 tgcgcgcgcg ctccgcccct gccggcgccg gcgtctcgcg gcggccggtg agcgcggcgg
    18421 cgcggctgct cagcgcgggc gggctgaccg tggtgctcgg gtcgttcggc tacgtgatgt
    18481 acgcggtgat gaccggcgcc aagctgggca gcccgggacc gctggtggcg ggccggccgg
    18541 tggtgtggct ggcgctccag gcgctggcgg tggcctgcgt ggtcgccacg gccgtcaccg
    18601 ggctggcgtg gtggcggcgg cgcgcgggcg tcgcggcggg cgagcgggtg cggctggccg
    18661 cgctgatggc cggggggctg gtgctcgtgc cgtgggggct gtactggggg ttgctgctcc
    18721 cggggctgtg agctgacggc ccggacgagg ttgtgtcggt cgcggctgct acacaggggc
    18781 catgggtgtg agcgtcgagg agttcctcga tctggtggac aagctgcccg aggtccgcag
    18841 ggaccgcatg gcgacctggg tcagcttcaa ggtgcgcggc aaggggttcg gctacctgtg
    18901 ggaggagacc gagaccgtcg gcgtcaaggc gaccgtcgag gagcagatcg cgctggtggc
    18961 cgagcggccc gaggtgttcg agccgcagtt caccgccggg cggttcgggt gggtggtgat
    19021 ccggctcgac cgcatcgact atgacgagct gttcgagctg gtggccgagg cgtggtgcct
    19081 gaccgccccc aagaccctgg tgacggcctt cgaatccgcc caccacatcg ggggataacc
    19141 tggcattaat gctgacaacg aacatccggc tgcgcgagtg gcgcgaggat gacgcccccg
    19201 ccgtgctggc cgccttccag gaccccgacc tgtcccgcca ggccccctgg ccggtcgtca
    19261 cgccgcagga cgcgctcggg tggatcgcct cgtgggacgg ggtggggcac gcgttcgcgg
    19321 tcacgctcgc ggggcgcgtc gtcggcaacg tggcggtggc ccgcatcgac gcccacgcca
    19381 acggctgggt ctcctactgg acggtccgcg aggcgcgcgg ccgcggcgtc gccccggcgg
    19441 cggtggagga gctggcccgg tgggcgttcc gggaacgcgg cctgttccgg ctggagctgg
    19501 ggcaccgcgt cgacaacccg gcctcgtgcc gggtcgccgt caaggcgggc ttccgcgccg
    19561 aggggatcga acgcgggaag ctcgcccacg acggggtccg ccacgacgtc gaacgccacg
    19621 cccgcctggc caccgactga cccggcgacc gtcttctccc cgcctcccgc gcacggaccg
    19681 gccgtgaggg ggcggcggcc tggggagagg gtggctggcg ggtggtcgcc ggggtgatct
    19741 accctcggtt gggtggacag cgagagcctg gcggccgccg gtctgctggc ggccatgagc
    19801 cgggcggcgg cgagcctcgc cgagttacgt caccccttcg tccgcagcga gcccttctgc
    19861 tacttcttcc ccccggccgg cgtccgcgcc ggcaccgcgt tcacgctgcc cgacggccgc
    19921 gaggtgagct tcaccgtctc catcgccgcc tccggcgggg cgttccacgt ggacggagcc
    19981 gcctcggccg agggggaggc gctgctcgac ctgccggccc gcacggcgtc cggcatcggc
    20041 gacggcatcg cggttctcga cgactacgcg gccgagctgg tctcctccgc cgcccgcctc
    20101 atcgatcagc tcctggacga gctcgtgtga ccgcgggctg atcgaactgg actctattgt
    20161 ctgattgtca gacaatgaag ccatgaagaa aggacctctg gccgtcgtgg gcgcctccgt
    20221 gctgtggggc acggccggca ccgcgggcct gctcgtctcc gccgactcgg tcgccctggc
    20281 cgccgcccgc ctggtcatcg gtggtgccgc cctcgcgctc ttcgcgggca agggggcgcg
    20341 ccgggcggtg agcccggcca cgctgctcgc cgccgtcgcg gtggccgcgt accagctctg
    20401 cttcttcgcg gcggtcggcc ggacgggcgt ggcggtcggc acggtggtcg cgatcggcag
    20461 cgggccggtg ttcaccgggc tgctgtcgtg gatcctgcac cgcgagcggc cgagcgggcg
    20521 ctgggcgctg gccaccgccg ccgccgtcgc cggctgcgcc gcgctcatcg cgggcggcgg
    20581 cgaggaggcc gccggcccgg gcgggcagat ggtgtccggg gtgctgttcg cgctgctggg
    20641 cggcctcgtc tacgccttct acgcggtctg cgccgcccgc gccatcgcca agggggcgcc
    20701 gtccgacggg gtgatgggcg tgctgttcgg cggcgcggcc gtgatcatgc tgccggtgct
    20761 gctctggagc ggcgcggggt ggctgggcga gccgaaggcg ctgctcgccg tcctctacct
    20821 cgggctggcc tcgacggcgc tgtcctacgt cctgtacggc aggggcctgc gcaccacgcc
    20881 ggtggccacg gcgtccacgc tggcgctggc cgagcccgcg gtcgccgccc tgctcgggct
    20941 ggtggtgctg ggcgagcggc tggccccggt gtcgtgggcg gggctcgcgc tgctggcggt
    21001 cagcctggtc gtcgtggccc tgcccgaccg gcggccccgg ccgggcgtgc ccgaggtcgt
    21061 gt
//
