LOCUS       NZ_JABWGO010000009     22634 bp    DNA     linear   CON 29-SEP-2024
DEFINITION  Nonomuraea rhodomycinica strain TBRC6557
            NODE_9_length_408698_cov_25.3413, whole genome shotgun sequence.
ACCESSION   NZ_JABWGO010000009
VERSION     NZ_JABWGO010000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nonomuraea rhodomycinica
  ORGANISM  Nonomuraea rhodomycinica
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 408698)
  AUTHORS   Chanama,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2020) Microbiology, Mahidol University, Faculty of
            Public Health, 420/1 Ratchawithi Road, Ratchathewi, Bangkok 10400,
            Thailand
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 26-MAY-2020
            Assembly Method                   :: SPAdes v. 3.10.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013363995.1-RS_2024_09_29
            Annotation Date                   :: 09/29/2024 04:09:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,940
            CDSs (total)                      :: 8,866
            Genes (coding)                    :: 8,758
            CDSs (with protein)               :: 8,758
            Genes (RNA)                       :: 74
            rRNAs                             :: 4, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 12 of 108
            Pseudo Genes (incomplete)         :: 99 of 108
            Pseudo Genes (internal stop)      :: 6 of 108
            Pseudo Genes (multiple problems)  :: 8 of 108
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:20:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 120361
            Orig. end                         :: 142995
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABWGO010000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22634
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22634
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22634
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12634](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12634)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     misc_feature    complement(231..246)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            complement(271..669)
                     /locus_tag="HT134_RS30585"
                     /old_locus_tag="HT134_30570"
     CDS             complement(271..669)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889816.1"
                     /locus_tag="HT134_RS30585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30570"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_175603949.1"
                     /transl_table=11
                     /translation="MKHWTEGFDDDHADEPLVRPYTITGGRTAPERDDLTLITLVTVIS
                     EAPADNSAGMRRLQPEHRTILALCKQPLAVAEIASALHLPVSVTKILIGDLIEAGHVRS
                     RPPLAFAQAGGLPGMSILEAVRDGLRKL"
     misc_feature    complement(322..324)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(666..1100)
                     /locus_tag="HT134_RS30590"
                     /old_locus_tag="HT134_30575"
     CDS             complement(666..1100)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889817.1"
                     /locus_tag="HT134_RS30590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30575"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_376768125.1"
                     /transl_table=11
                     /translation="MMTQRTTATDTDLDWLLDGLVDQVAGTRHAIVLSDDGLVISRSRT
                     IERSDAERLAAIATGQQSLARGVGQLFSGGPVHQVIIEMAELWLFITAAGRGTHLAVVA
                     SQEVDAELMSVAMHTLIQQVGQKLGTDARTPPADEAGRRG"
     gene            complement(1097..3661)
                     /locus_tag="HT134_RS30595"
                     /old_locus_tag="HT134_30580"
     CDS             complement(1097..3661)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546388.1"
                     /locus_tag="HT134_RS30595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30580"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_312888566.1"
                     /transl_table=11
                     /translation="MAGLGRVGRRRTEPGRDGLPESAGAGPRRLPGRRRLRLRTVLIIV
                     VVVPTVTFAPLLGSGMFQLFSQWQAEVAQLELAAVTVGRPAANLFFNLDRERRITAEAQ
                     AEPGEDTGDKLAKQRAETDKAVAAFRPVANLDTSKGPEGTTDAIARTQRALGLLEQQRR
                     AVDAGWSSAQNAYDYYNSVIEADLGLLTALSRTDHGEVSTGAQTLVDLFWVVDMIGRED
                     AVLARGWGAGRLTRDEYALVTDAAGTRNHLMRDRVVPSLGGNESRYRTLTTSKAWKTMA
                     DLEERLVASGGGADDKQVKLRPVGSTWRSSVDAISPQLLDLLALRLENVAKIGYSHAKQ
                     LFVIFISITSVGVLALALVIITSWRLTAVLRRRILQLRQEALELQERLPDVVTRLERGE
                     DVDVEAEVHMVDPTPDELGELGQALNMASRSAVATAVRQAEQHRGFQRMLQRIARRTQI
                     LIGLQLKKLDELERRYEDPEVLEGLFDLDHLTARLRRYEENLVILGGGQPQRRWRKPVR
                     LLDVLRAAQGEVQDYRRITIDVEGEPWVAERAVGALVHVLAELMENATAFSRPPTPVEV
                     RAAMVSRGIAVEIEDRGLGMEPEQYAAANALMRTPPQLDVMAQADDVRLGLYVVARLSA
                     GLGLQVELRQSAFGGTRVIVLLPDSLVVERPRLVPGPAARPEEAPQDPTGPHPHPYPQE
                     GAAGPRRPQEGSQEGFQEGPQDRPGESPDEKPHDRPYDGPYEKPRDTTQLPTRSRGRAM
                     AYVTAPGAGSPDRGDAPAPPGSRPLPQRVRQASLVTELKVPADREERTEQDLWTVRDQP
                     TRSGATIGAFQRQSRRRRAGDDALQPGPDGSAEPPSPTTEDR"
     misc_feature    complement(3605..3607)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3791..4789
                     /locus_tag="HT134_RS30600"
                     /old_locus_tag="HT134_30585"
     CDS             3791..4789
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003772115.1"
                     /locus_tag="HT134_RS30600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30585"
                     /product="S66 peptidase family protein"
                     /protein_id="WP_217708570.1"
                     /transl_table=11
                     /translation="MTDVIFPPKLKAGDVVRVVAPARSRAMVMEHDHTGVIASRFAELG
                     LTLTYGGHVDERDAFDSSSVASRVADLHEAFADPSVAAILTVIGGYNSNELLPYLDWEL
                     IRANPKILCGYSDITALQNAVLARTGLVTYSGPHWSTFGMRDHFEQTLRWFTSVLFDTD
                     PVALTPAAHWSDDLWFLDQDKREQIPNDGWWPMRPGSGEGRIVGGNLCTLNLLQGTPYL
                     PSLDGALLIVEDDFESHPATFARDLTSLLQLPDAANIRGLAIGRFQKASRMSRPLLEQI
                     IANQPIPAGVPVLANIDVGHTHPLATFPVGGRGRLVVGGAGTDTGLTLLRH"
     gene            4916..5482
                     /locus_tag="HT134_RS30605"
                     /old_locus_tag="HT134_30590"
     CDS             4916..5482
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630587.1"
                     /locus_tag="HT134_RS30605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30590"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_175603950.1"
                     /transl_table=11
                     /translation="MARPATAEASDADLIGRSFEEPEAFAAVFDRHAPALHRYAARRLG
                     PDAAEDVVSETFLAAFEHRHRYQSGQADARPWLYGIASNVIGKRRRREVARYRAYVRGG
                     VDPAEIVGGPVEDGVGTLAVNRPLVAALAGLRTGDRDVLLLVAWAELTYEEVAEALDVP
                     VGTVRSRLNRARRKVRQALEGANHG"
     gene            5475..6557
                     /locus_tag="HT134_RS30610"
                     /old_locus_tag="HT134_30595"
     CDS             5475..6557
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038083.1"
                     /locus_tag="HT134_RS30610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30595"
                     /product="CU044_5270 family protein"
                     /protein_id="WP_175603951.1"
                     /transl_table=11
                     /translation="MDEMAELARLWAEVPEATERDLAGSRAVLASRFDRPRRGWRGALA
                     SRSDRPRRGWREALPVRRVALAGAIAVTLTAGVLVAEVGLGGSGPHGPGSLIGAPPADA
                     KTLLSLAARAATDQPDMVPARGEYVHTRRLAQQSLYTEDEAGRTQYTKVLVNEERWEAA
                     DVGKPWLSREQAVSAIGPAPRTSWDHGTEDTVYEPATCPGRPAYARLGAWPTDPAQVRA
                     KLVAETGGEEPLRVWSALQGLVAESVVRPSLSAALYQVAAGLDGIVLVPDAVDAAGRPG
                     LAVAMDEGDGTRSELIFDRHTYRYLGERTVNTRDRKVRLPNREVTARKGAANGTAVLAV
                     DLVPALPEVSPDASRMEIPC"
     gene            6633..7475
                     /locus_tag="HT134_RS30615"
                     /old_locus_tag="HT134_30600"
     CDS             6633..7475
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS30615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HT134_30600"
                     /product="hypothetical protein"
                     /protein_id="WP_175603952.1"
                     /transl_table=11
                     /translation="MFIAAKAVAVTLLVGSFGASTSPETQAAYEKKAAVEQTRVACMKE
                     QGLTYLAQPVTKRKRQPGERERITGDYAALRAYRAKYGFGVWSPLVFPRDPVVNPVSGE
                     NPNNDTMMAMSAEELKKWRAADDRCFAKAAEQHLGKTVTSYDGYLTRLDAALDASLVPL
                     DEDGQLTRLGRQFAKCLGVGQAKPSVLAVLGRSQYTKQAGEVARKNWKGELPKAPEGRT
                     IILKPQLKPAEAKPYLDKEIRSALKDLECGKSFYAAYSPRAWAAKERVYQEFAVDFAL"
     gene            7555..8757
                     /locus_tag="HT134_RS30620"
                     /old_locus_tag="HT134_30605"
     CDS             7555..8757
                     /EC_number="3.1.1.-"
                     /GO_function="GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017580232.1"
                     /locus_tag="HT134_RS30620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30605"
                     /product="erythromycin esterase family protein"
                     /protein_id="WP_175603953.1"
                     /transl_table=11
                     /translation="MDISVKDATHAVDAAAVLRLFPARPRLLALGEPTHGEDALLRLRN
                     ELFRQLVEQEGYRTIGIESDCVLGLAVDDYVTSGTGTLDEVMERGFSHGWGASAANREL
                     VRWMRAYNDGRAPAERLRFAGCDGPLEITHAASPRRPLTALHGYLAAHVDADLLPCTAD
                     TLDGLLGADDRWTDPAATTDPSRSVGRSAEARELLLLADDLVALLDAETPRLIAASARD
                     GWDRARLYGRAATGLLRYHFWLADTSPGRMTRLLGLRSSMIAANLLAVAERGPALVHAH
                     NLHFQRHRSTMRLGELPVEWWSAGAIVRAHLGEEFAFLATALGTMRHQGVETPPPDTVE
                     GLLYALPQERCVVGTGRLAAALGGAALAARTSPWFGYFPLDPEQLTGSDGIVFVKDVPR
                     S"
     gene            complement(8735..9058)
                     /locus_tag="HT134_RS30625"
                     /old_locus_tag="HT134_30610"
     CDS             complement(8735..9058)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS30625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HT134_30610"
                     /product="hypothetical protein"
                     /protein_id="WP_175603954.1"
                     /transl_table=11
                     /translation="MPVAQAAHATSAAPASPARPARPAAVAPAPPSVHHRALLTWLAVY
                     SMIMVVQLLLGPAIAPLPMPLRTLILTGVVVPTVVYLLMPLLLRAHARMPRRGRRPSSA
                     GRP"
     gene            9186..9770
                     /locus_tag="HT134_RS30630"
                     /old_locus_tag="HT134_30615"
     CDS             9186..9770
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF037675.5"
                     /locus_tag="HT134_RS30630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30615"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_175603955.1"
                     /transl_table=11
                     /translation="MAWDTARTRQLLLDAAVEEFAEHGPQGARVDRVAAKAGVNKERIY
                     QYFGNKDQLFGAVLTQELERLAAAVPLDAAQAADLGGYAGRVFDYHSSHPHLVRLLHWE
                     GLHAGDAEVPAEAARTAHYAGKVAALAAAQEEGSLTGALPPADLVYAVIALAGWWFSTP
                     QLARMIRAGVPDDSPAARREALIRLVRALVA"
     gene            complement(10001..12634)
                     /gene="lanL"
                     /locus_tag="HT134_RS30635"
                     /old_locus_tag="HT134_30620"
     CDS             complement(10001..12634)
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="HT134_RS30635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30620"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_246365891.1"
                     /sec_met_domain="Pkinase (E-value: 7.6e-13, bitscore: 43.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.7e-23, bitscore:
                     76.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCEAGSQDWVEQVVRQCVGADHTVTGGSVWLVVRPDRAVLPDHGW
                     KLHVSSRASNFPALVEKLVPLLVAEGCVFKLARSRQVLHELNDGRTVPESVGKAFTVYP
                     DQHRVRDVGLLLARTLTGHQGPRVLSDRRVSADAPVYYRYGGFVTRRSTDVRGQSITQL
                     RGPAGEEFDEAAGLSYRQPSWVEDPFTGARPEPGRSGDDLLLSGRYRVVVGIREAAQGN
                     VYRAIDERTGGRVVVKQARAFVAEHGDGNDGRLRLRNERRVLEALDGVAGVPRFLDHFR
                     YGDDEFLVTTDRGPATLAEDVRRNGPYRTGPGAGARSLDRLAGELARILTAVHERGVMM
                     RDLSAANVVIGDGASLIDFGLASYDGLHLSGLTPGYAPARQVRGEPPRAADDLHALGMT
                     LVYAATGLHPVTLGDDPELPRTRALQTVSRYHGPTPSGTMSAVVDLLGDEERARAAVLR
                     LASGDDRRTVSPPTPVATAPVATAPVVTAPVVTAPVVTAPVVAGPVVAAPVVTADVAAE
                     VLDNLVGDLLDLVDGVLEAPAGTKAANDASVYSGSAGIGLELLHHRHRPAAERKLRELV
                     DFTVRVTAPLTPQPGLFTGVTGTDVFLQEAGDRGISPAGGRPGRSLPPPEWRPEAADLT
                     DGDAGAGLGHLYFHRLTGDPADLEAARRCARAVVAERPLPRASRPGEADVTAGRAHGLA
                     GTTALLLGLAEETGESWVLEAAADRVRLLSERARVLVREAEDPAAEPMTMSWCRGLAGV
                     GPTLLHASKVLGDPALADLARRGADVCVARMSRLSALGQCCGVAGVGNYLLTLAELEQS
                     ERHRAAAYDLATHLLLRSAGSPLHPTFFAPGDPPARSLSWAQGLTGVVTFFRRLAYGGP
                     DCLPVG"
     misc_feature    complement(12494..12496)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12515..12517)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12695..12820)
                     /locus_tag="HT134_RS47215"
     CDS             complement(12695..12820)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS47215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_281387743.1"
                     /transl_table=11
                     /translation="MEPRVAGTDVMEPVVEFEQRWESQVDQDRCPVTRPGVSKIC"
     misc_feature    complement(12857..12877)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.35"
                     /tool="antismash"
     misc_feature    12960..12974
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.9"
                     /tool="antismash"
     misc_feature    complement(13007..13018)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.28"
                     /tool="antismash"
     gene            complement(13056..13940)
                     /locus_tag="HT134_RS30640"
                     /old_locus_tag="HT134_30625"
     CDS             complement(13056..13940)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.5"
                     /locus_tag="HT134_RS30640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30625"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_175603957.1"
                     /transl_table=11
                     /translation="MRSLPSVEDLRLVEALVRHGSLGAAGRELLISQPAASNRLAALER
                     RIGERLFDRDTTGARPTPAGRALAAEAAHVLEHLEAIFDRTRAAARAGSLRAGTFGSLA
                     PWVFPALEDLLGEVTVHQVADHGDRLVEWVGEGSMDVAFVAIADQMRLPATVTALPVAR
                     DRLVVLVPAGARLGSGRKPFAGLDVVAYTYDASTAALHRRLSELGGRPRRAATAETAVR
                     MGRLLGCPIVLPSGPAVSYAGPGEEIAAMTIPGRLTLFMVTRRPMPPELSAAAAGLAAR
                     LGLEPASDSSPPG"
     gene            14013..15296
                     /locus_tag="HT134_RS30645"
                     /old_locus_tag="HT134_30630"
     CDS             14013..15296
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS30645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HT134_30630"
                     /product="MFS transporter"
                     /protein_id="WP_175603958.1"
                     /transl_table=11
                     /translation="MTSRRDIAAMLLTTFLTWMGQRTTAVALPLVALAETGSPWTTGLV
                     GGAVGLPMLTSAWWARGLRQRLTTGRALAGVLAVQVAGLLVVPVGAALGTVGSIHLAAT
                     GLITGCATAVGAPAQRALLADLCDRLGAGVAARMLAWQDFAHRSTMILAPPLAGWAITA
                     TGPFHLLWAEAAGVGLGAAVLLTVRGAATATTGGDDASASPGGDDASATPGGDDASASP
                     GGDAPALRHVLARHPEIRRAVTMSGVGGLVWFAFTLGLAILGAETGRPGLLISAGMTGY
                     GAGSLVGALLAPAVVPRLPALGTMATGWVILGASFIALPAVTSSLPLIACLAAAGGFAM
                     PLGIGSMNRLITVRTDGAERRAAFAAESLVHDGAVSLGLLAGGAVIGLAGAGPTLVVAG
                     AAQVAVALVAGPWLIPVPAREPVRSTLQ"
     gene            15302..16051
                     /locus_tag="HT134_RS30650"
                     /old_locus_tag="HT134_30635"
     CDS             15302..16051
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039735.4"
                     /locus_tag="HT134_RS30650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30635"
                     /product="DUF6348 family protein"
                     /protein_id="WP_217708572.1"
                     /transl_table=11
                     /translation="MNDGRTGAMDERLPDEVVLGMIARRLSEAMDQPWHVTGDLAKGPG
                     SLAVVLGEDHTGHPGHVDIDFVLNVDRPGNTTISDCATGYGTTPEETVERAIEIWLGTT
                     GSALLELLAQDGSFAGHYAADDPDGFPGWHMIHGGITGWGIGDDFQAVQRWAADNPLAP
                     HLAPALRSSFDRDHLIGVKAFFGSGGDSETAEIRVDGIHHEAASEVLAGLPWPRPAGGM
                     SYARTFLLLVHNEGGDEGRERGRDETA"
     gene            complement(16058..17056)
                     /locus_tag="HT134_RS30655"
                     /old_locus_tag="HT134_30640"
     CDS             complement(16058..17056)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF014684.5"
                     /locus_tag="HT134_RS30655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30640"
                     /product="ABC transporter permease"
                     /protein_id="WP_175603960.1"
                     /transl_table=11
                     /translation="MIKRLVLGEAGIGVALVVLAGFFVIAAPNFATEQNLRNIMTQITL
                     NTVLAVGMTFVILVGGIDLSVGSAMALCAVVSGTMMAGSHSAVTLLGAILVSVLVGGAV
                     GWINGFVSEQWRVPSFIVTLAMLNVARGAAERYTDAATIYNLPAALNDFGTITLLGVPA
                     VFWVALLLAGIGWFVLSRTVFGRLIYATGNNEEAVRLSGHKTSRIKIAAFMIAGLTVGI
                     AAVLYMARLNIASPILGQGYELNAIAAVVIGGASLMGGRGSMAGTFLGACLLGVLTNGL
                     LLMGVSDFERQIITGLVILVAVVLDAYRLRLARKLAVTQPAKEPVPAAVAS"
     gene            complement(17053..18540)
                     /locus_tag="HT134_RS30660"
                     /old_locus_tag="HT134_30645"
     CDS             complement(17053..18540)
                     /EC_number="7.5.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014909663.1"
                     /locus_tag="HT134_RS30660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30645"
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="WP_175603961.1"
                     /transl_table=11
                     /translation="MMTVTGLVKRFPGVVALDGVDLDIRAGEIHALVGENGAGKSTLVK
                     ALAGIHAPDAGTMTFDGVPYTPAGAADGLAAGISVVHQELALLPYLTVAENLFLRGLPR
                     TAGVVDRKRLRADAARLLEQVGLDVAPDTPVERLGIAQMQLVEIAKAISTDSKLLIMDE
                     PTATLTSREAGRLFGILRGLRERGVAIVYISHHLQEVLELADRVTVLRNGRSIETREMA
                     GVTAPDLVRLMVGRDLAQEYPVKPPTAPGEVAIEVRELKVAGFEGPLSFSVRRGEVVGL
                     AGLVGSGRTEAMRAIFGADPAVSGNIKLYGEKVHIRHPKDAVRHGISLLTEDRKSQGLV
                     LDLPISANVTLAKLRGLLLRFGQERSLSEDLGRRLHLRSAGVGQHVRTLSGGNQQKVVL
                     AKWLNAGSDILIVDEPTRGIDVGAKYEIHELLLGLAAEGKALIVVSSDLPELMGVCDRI
                     LVFSRGKIAGEVARPDFDAEHILTLAYSGYLKNGETQ"
     gene            complement(18537..19505)
                     /locus_tag="HT134_RS30665"
                     /old_locus_tag="HT134_30650"
     CDS             complement(18537..19505)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF024799.5"
                     /locus_tag="HT134_RS30665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30650"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_175603962.1"
                     /transl_table=11
                     /translation="MNKKIVAVAGLALALTACGKEGGTAAEPAAAPKPGEKPGVCLVMK
                     SLANEFFQQMQKGAEEHAAKRGDLTLSVVGIQNETDIDNQVAAVEKCVTQQAKAIVIAP
                     ADSRALVAPLKRAVDAGVKVVNIDVQLEEGAMKAAGIGDKVPFVGPDNREGAKQSGMEL
                     AKAVGKDAEVVILEGNPGAANAAQRKAGFEDAVKEGGLKLVDSKTAHWETNEAHTVFSN
                     MLTAHPNIKGVLAGNDNMALGALKAIDEQGKKGQIKVASFDNIPAIAQYVKDGTVVSTL
                     DQYGAQQAANGIDYAMKMIGGENFSGWQKTEIKLITKDNLG"
     gene            complement(19518..19898)
                     /gene="rbsD"
                     /locus_tag="HT134_RS30670"
                     /old_locus_tag="HT134_30655"
     CDS             complement(19518..19898)
                     /EC_number="5.4.99.62"
                     /GO_function="GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="rbsD"
                     /inference="COORDINATES: protein motif:HMM:NF008761.0"
                     /locus_tag="HT134_RS30670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30655"
                     /product="D-ribose pyranase"
                     /protein_id="WP_312888569.1"
                     /transl_table=11
                     /translation="MRHDGLWHPRLLQILSAAGHTDLIVVADPGLPVPPGVETVDLVWR
                     RGEPAFLPVLEAVLGELVVEAAYVAEESPPGFLDELLKNTTRTQRIPHTRLKELTGRAR
                     AVVRTGEATPYANVVLQAGVPF"
     gene            complement(19888..20907)
                     /locus_tag="HT134_RS30675"
                     /old_locus_tag="HT134_30660"
     CDS             complement(19888..20907)
                     /EC_number="2.7.1.15"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547222.1"
                     /locus_tag="HT134_RS30675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30660"
                     /product="ribokinase"
                     /protein_id="WP_175603964.1"
                     /transl_table=11
                     /translation="MPETTPRNAAETAPGTTAGTARELELVVVGSLNMDLTVPVTRLPG
                     RGETVAGAAVVRAAGGKGANQAVAAARLGARVRLVGQVGDDALGRELLAAVAGEGVDVS
                     GVRRVPAATGMAMIVVEDGGENMITVAPGANSLFHLTDPGSAATGPGSVTTGLDLAGPG
                     SPATGLDLARADALLLQLEIPVAACLAAARQARAHGVPVILNAAPYTDGLDDLLPLVDL
                     LIVNESEADALCRGADPAGLLALGPRAAVVTLGGRGARGRDASGACEAPSFRVPVVDAV
                     GAGDTFCAQLALAHAAGLPLADAVRRACAAGALATTAHGAQTAMPTGGQVERLLARAS"
     gene            complement(20900..21925)
                     /locus_tag="HT134_RS30680"
                     /old_locus_tag="HT134_30665"
     CDS             complement(20900..21925)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012742.5"
                     /locus_tag="HT134_RS30680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_30665"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_175603965.1"
                     /transl_table=11
                     /translation="MVTRRDVARLAGTSEAVVSYVLNNGPRNVAPHTRERVLRAIDELG
                     YRPNAVARSLRTSRTHTIGLVVPDNANPFFAELAREIEDVAFENGLTVLLGNAMDDDDR
                     EAAYVRTLIDRQVDGLILIPAHGPRAWRSQLAASGVPCIVLDRELDDTPASHLLLDNEG
                     GAYEATTHLLEHGQRRIGCVAGPKDIHPTVDRVAGWSRALTEAGIDPASMPLAHGPYGR
                     RQGYLSGRRLLSREDRPTALFVTSDEQAIGVMRAAAELGLSVPADIALCSIDGIAASSY
                     TVPALTTMRQPIEELGRRAVELLAAQIGDSPGGERVVLSATLIRRGSCGCPDPAGGLDD
                     A"
     misc_feature    21938..21953
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.15"
                     /tool="antismash"
     misc_feature    22000..22017
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    complement(22186..22202)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.82"
                     /tool="antismash"
ORIGIN
        1 atgaaccaga agcgttcctg cccgggggtg ccgaacaggt agaggacgag gtcgccgttg
       61 atggtgatgc gcccgaagtc cagcgccacc gtggtggtgg actttccgcc caccccttcg
      121 aggtcgtcca caccgatgct ggcgtgggtc aggtactcct cggtgcggag cggggcgacc
      181 tcgctgaccg cgccgaccag ggtggtcttc ccgacgccga aaccacccgc gataaggatc
      241 ttcactgcca ggggggcgcg agccccgtgg tcagagcttg cgaagcccat ccctcaccgc
      301 ctcaaggatt gacatgccag gtaagccgcc cgcctgcgcg aaggccaggg gcggccggga
      361 ccgcacgtga ccggcctcga tcagatcacc gatcaggatc ttggtcaccg acaccgggag
      421 gtgcagcgcg gaggcgatct cggcgaccgc cagcggctgc ttgcacagag cgaggatggt
      481 gcggtgctcc ggttgcagcc ggcgcatgcc ggctgagttg tccgcggggg cctcggagat
      541 caccgtcacc agggtgatca gcgtgaggtc gtcccgctcc ggagcggttc gcccgccggt
      601 gatcgtatag ggacggacaa ggggctcgtc ggcgtggtcg tcgtcgaagc cctccgtcca
      661 gtgcttcatc cgcgtctccc cgcctcgtcg gccggcgggg tacgcgcgtc ggtgcccagc
      721 ttctggccga cctgctggat cagggtgtgc atcgcgacgc tcatcagctc ggcgtcgacc
      781 tcctgggagg cgaccacggc caggtgggtg ccgcggcccg cggccgtgat gaacagccac
      841 agctcggcca tctcgatgat gacctggtgg accggcccgc cgctgaacag ctgccccacg
      901 ccgcgggcca ggctctgctg gccggtggcg atcgcggcga ggcgttcggc gtccgagcgt
      961 tcgatggtcc gggagcggct gatcaccagg ccgtcgtcgg acagcacgat ggcgtgcctg
     1021 gtgcccgcga cctgatcgac caggccgtcc aggagccagt ccaggtctgt gtcggtggcg
     1081 gtggttcgct gcgtcatcat cgatcttccg tcgtagggga agggggctcg gcggatccgt
     1141 ccggccccgg ctggagggcg tcgtcaccgg cccggcgcct gcgggactgc ctctggaagg
     1201 cgccgatcgt ggcgccggac cgggtgggct ggtcgcgtac ggtccagagg tcctgctcgg
     1261 tccgctcctc ccggtccgcg gggaccttga gctcggtgac caggctggcc tggcgcaccc
     1321 gctggggcag cggccggctg ccgggcggcg cgggcgcgtc gccgcggtcc ggtgatccgg
     1381 cgccgggcgc cgtgacgtag gccatcgcgc gtccccggga acgagtcggc agctgcgtgg
     1441 tgtcgcgcgg cttctcgtag ggcccgtcgt agggcctgtc gtgaggcttc tcgtcggggc
     1501 tttcgccggg cctgtcctga ggcccttcct ggaacccttc ctgggaccct tcctgcggcc
     1561 ggcgcggacc ggccgcgcct tcctgcgggt acgggtgcgg gtgcgggccc gtggggtcct
     1621 ggggggcctc ctcggggcgc gcggccgggc ccggcaccag gcggggtcgc tccaccacca
     1681 gcgagtccgg cagcagcacg atgacccggg tgccgccgaa ggccgactgc cgcagctcca
     1741 cctgcaggcc caggcccgcg gagagccggg cgaccacgta caggccgagc cgcacgtcgt
     1801 cggcctgcgc catcacgtcg agctgcggcg gcgtccgcat gagggcgttg gcggcggcgt
     1861 actgctcggg ctccatgccc aggccgcggt cctcgatctc cacggcgatg ccccggctga
     1921 ccatggcggc ccgcacctcg acgggggtcg gcggcctgga gaaggcggtg gcgttctcca
     1981 tgagctccgc caggacgtgg accagcgctc ccacggcgcg ctcggccacc cagggctcgc
     2041 cctcgacgtc gatcgtgatc cgccggtagt cctggacctc gccctgcgcg gcgcgcagca
     2101 cgtcgagcag gcgtacgggc ttgcgccagc ggcgctgcgg ctggccgccg ccgaggatca
     2161 ccaggttctc ctcgtagcgg cgcaggcggg cggtgaggtg gtccaggtcg aacagtccct
     2221 ccagcacctc ggggtcctcg tacctgcgtt ccagctcgtc cagcttcttc agctggagac
     2281 cgatgaggat ctgggtgcgg cgggcgatgc gctgcagcat gcgctggaat ccgcggtgct
     2341 gctcggcctg gcgcacggcg gtggcgacgg cgctgcggct ggccatgttg agggcctgcc
     2401 cgagctcgcc cagctcgtcg ggcgtggggt cgaccatgtg tacttccgcc tccacgtcga
     2461 cgtcctcgcc gcgctccagc cgggtgacca cgtcgggcag ccgttcctgg agttccaggg
     2521 cctcctgccg gagctggagg atgcgccgcc ggagaacggc ggtgagacgc cagctcgtga
     2581 tgatcaccag ggccagggcg agcactccca cgctggtgat gctgatgaag atcacgaaga
     2641 gctgtttggc gtgactgtag ccgatcttcg ccacgttttc gagccggagg gcgagcaggt
     2701 ccagcagctg ggggctgatc gcgtccaccg aggaacgcca cgtggagccg accgggcgca
     2761 gcttcacctg cttgtcgtcg gccccgcccc cggaggcgac cagccgctcc tccaggtcgg
     2821 ccatggtctt ccacgccttg ctggtcgtca gcgtccggta gcggctctcg ttgccgccga
     2881 gactgggcac cacccggtcc cgcatgaggt ggttcctggt gccggcggcg tcggtgacga
     2941 gggcgtactc gtcccgtgtc aggcgccccg ccccccagcc gcgggccagg acggcgtcct
     3001 cacggccgat catgtcgacg acccagaaga ggtcgaccag cgtctgcgcg cctgtgctga
     3061 cctcgccgtg gtcggtacgg ctgagggcgg tcagcaggcc gaggtccgcc tcgatgacgc
     3121 tgttgtagta gtcgtaggcg ttctgggcgc tggaccagcc ggcgtccacc gcccggcgct
     3181 gctgctccag cagcccgagc gcgcgctggg tccgcgcgat ggcgtccgtg gtgccctccg
     3241 ggcccttgga cgtgtccagg ttcgccaccg ggcggaaggc ggccacggcc ttgtcggtct
     3301 ccgcgcgctg cttggcgagc ttgtcgccgg tgtcctcacc gggctcggcc tgggcctccg
     3361 cggtgatccg ccgctcccgg tcgaggttga agaacaggtt ggccgcgggc cggcccacgg
     3421 tgacggcggc cagctccagc tgggccacct ccgcctgcca ctggctgaac agctggaaca
     3481 tgccagagcc cagcagcggg gcgaaggtca cggtcggcac gaccacgacg atgatcagca
     3541 cggtgcgcag gcgcagccgg cggcgaccgg gcagccgccg cggcccggct ccggcggact
     3601 ccggtaagcc gtcgcggccg ggttccgttc gtcgtcgccc gaccctgccc aagccagcca
     3661 cgtgcgggac actctcctcg gtgcgttcat cgcgaatatc gccaaagtag gcgattggtg
     3721 cccgatagta gccacaccac acatgacccg gaagccccag gttccccggt agtaccgtta
     3781 cgcttcgacg atgacggacg tgatcttccc tcccaagctg aaggcgggcg acgtcgtccg
     3841 cgtcgtggcg ccggccaggt cccgcgcgat ggtcatggag cacgatcaca cgggcgtcat
     3901 cgcgtcacgg ttcgccgagc tcggcctcac gctcacctac ggcggccatg tcgacgagcg
     3961 ggacgcgttc gactcctcca gcgtcgcctc gcgggtcgcc gacctgcacg aggcgttcgc
     4021 cgacccgtcg gtggcggcga tcctgaccgt catcggcggc tacaactcca acgagctcct
     4081 gccgtacctg gactgggagc tgatccgcgc caacccgaag atcctgtgcg ggtactccga
     4141 catcaccgcc ctgcagaacg ccgtcctcgc gcggaccggg ctggtcacct actccggccc
     4201 gcactggtcc acgttcggga tgcgggacca cttcgagcag accctgcgct ggttcacgtc
     4261 ggtcctgttc gacaccgatc cggtcgcgct gaccccggcc gcgcactgga gcgacgacct
     4321 gtggttcctc gaccaggaca agcgcgagca gatccccaac gacgggtggt ggccgatgcg
     4381 gcccggcagc ggcgagggcc gcatcgtcgg cggcaacctc tgcacgctga acctgctgca
     4441 gggcaccccg tacctgccgt cgctcgacgg cgcgctgctg atcgtcgagg acgacttcga
     4501 gtcgcacccg gcgacgttcg cccgcgacct gacctcactg ctgcagctcc ccgacgcggc
     4561 gaacatccgg gggctggcga tcggccggtt ccagaaggcc agccgcatgt cccgcccgct
     4621 gctggaacag atcatcgcca accagccgat cccggccggc gtccccgtcc tggccaacat
     4681 cgacgtcggc cacacccacc ccttggccac gttccccgtc ggcggccggg gcaggctcgt
     4741 cgtcggcggc gccgggaccg acaccggtct gaccctgctg cgccactgac ctcgacggct
     4801 tgcgtccttc gagcggtatc ggcccggcgt gaactcttcg gcggtgcagc ggtaagtaca
     4861 ggcgaatctg cccgcctgcc gcacctcggc accgcgtgaa ggagctgacc agtccatggc
     4921 cagaccggcg acagccgagg cctccgacgc cgatctgatc ggccggtcgt tcgaggagcc
     4981 ggaggcgttc gccgccgtgt tcgaccggca cgcgccggcc ctgcaccgct acgcggcccg
     5041 caggctcggg cccgacgcgg ccgaggacgt ggtgtccgag acgttccttg cggcgttcga
     5101 gcaccggcac cgctaccagt ccggccaggc cgacgcccgg ccctggttgt acggcatcgc
     5161 ctcgaacgtg atcggcaaac ggcggcggcg cgaggtggcc cgctaccgcg cgtacgtgcg
     5221 cggcggtgtg gaccccgcgg agatcgtcgg cgggccggtg gaggacggcg tgggcacgct
     5281 cgcggtcaac aggccgctgg tggccgctct ggccgggttg cgcaccggtg accgggacgt
     5341 gctgctgctg gtggcgtggg cggagctgac gtacgaggag gtggccgagg cgctggacgt
     5401 cccggtcggg accgtgcggt cccggctcaa ccgggcgcgc aggaaggtcc gccaggcgct
     5461 ggaaggagcg aaccatggat gagatggcgg agctcgcccg gctgtgggcg gaggtccccg
     5521 aggcgaccga gcgcgacctg gccggctccc gtgccgtcct ggcgtcccgg ttcgaccgtc
     5581 cccgccgcgg gtggcgtggg gcgctcgcgt cccggtcgga ccgtccccgc cgcgggtggc
     5641 gtgaggcgct gccggtgcgg cgggtcgcgc tcgccggggc gatcgcggtg acgctcaccg
     5701 ccggcgtcct cgtcgccgag gtgggtctgg gcggctccgg cccgcacggc cccggatccc
     5761 tgatcggcgc gccgccggcc gacgccaaga cgctgctctc gctggccgcg cgggccgcca
     5821 ccgaccagcc cgacatggtg ccggcccgcg gcgagtacgt ccacaccagg cggctggccc
     5881 agcagagcct gtacaccgag gacgaggcgg gcaggacgca gtacaccaag gtgctggtca
     5941 acgaggagcg ctgggaggcc gcggacgtgg gcaagccctg gctgagccgc gagcaggccg
     6001 tctcggccat cggtccggcg ccccggacct cctgggacca cggcaccgag gacaccgtgt
     6061 acgagccggc gacctgcccc ggccggcccg cgtacgcccg gctgggcgcc tggccgacgg
     6121 accccgcgca ggtgcgcgcc aagctcgtgg ccgagacggg cggcgaggaa ccgctgcgcg
     6181 tctggtccgc gctccagggt ctggtcgccg agtcggtggt acgtcccagc ctgagcgccg
     6241 cgctgtacca ggtggccgcc gggctcgacg gcatcgtgct cgtccccgac gccgtggacg
     6301 ccgccggccg ccccggcctc gccgtcgcca tggacgaggg cgacggcacc cggtcggagc
     6361 tcatcttcga ccggcacacc tatcgctacc tgggcgagcg cacggtcaac accagggaca
     6421 ggaaggtgag gctgcccaac cgcgaggtca ccgcgcgcaa gggcgcggcg aacggcacgg
     6481 ccgtgctcgc cgtcgatctc gtcccggcgc tgccggaggt gtcgccggac gcgtcccgca
     6541 tggagattcc ctgctgagtc ttccccccga tccggccttt tcggccggag gttctgtttc
     6601 gcatgcccat tttcgagaga aggagcacac ccatgttcat cgcagcgaag gccgtcgcgg
     6661 tcaccctgct cgtcggctcg ttcggcgctt ccacctcgcc ggagacgcag gccgcgtacg
     6721 agaagaaggc cgccgtcgag cagacgcggg tcgcctgcat gaaggagcag ggcttgacct
     6781 acctggccca gccggtgacg aagcgcaagc ggcagcccgg ggagcgcgaa cggatcacgg
     6841 gtgattacgc ggcgttgcgt gcgtaccggg ccaagtacgg cttcggcgtc tggtccccgc
     6901 tcgtctttcc gcgcgacccg gtggtcaacc ccgtgtccgg ggagaacccg aacaacgaca
     6961 ccatgatggc gatgtccgcg gaggagctga agaagtggcg cgcggccgac gaccgctgct
     7021 tcgccaaggc cgccgagcag cacctgggca agaccgtcac ctcctacgac ggctacctca
     7081 cccggctcga cgcggcgctg gacgcgtcgc tcgtcccgct ggacgaggac gggcagctca
     7141 cgcggctcgg ccggcagttc gccaagtgcc tgggcgtcgg ccaggccaag ccctcggtcc
     7201 tggccgtact cggccggtcg cagtacacga agcaggccgg cgaggtcgcc aggaagaact
     7261 ggaagggcga gctgccgaag gcccccgagg gccgcaccat catcctgaag ccgcagctga
     7321 agcccgcgga ggccaagccg tacctggaca aggagatcag gtcggccctg aaggacctgg
     7381 agtgcgggaa gtccttctac gccgcctact cgcccagggc gtgggcggcc aaggagcgcg
     7441 tgtaccagga gttcgccgtg gacttcgctc tctgagcttt taaggttgtc ccttcctgtc
     7501 gcggccggat cgcggaaaag cttccacaga cggttcagag ataccgttga aggcatggac
     7561 atcagcgtca aggacgccac tcatgccgtc gacgccgccg ccgtcctgag gctgttcccg
     7621 gcccggccgc gactgctcgc cctcggcgag cccacccacg gcgaggacgc cctgctgcgc
     7681 ctgcgcaacg agctgttccg gcagctcgtc gagcaggagg gctaccggac gatcgggatc
     7741 gagagcgact gcgtgctggg cctggccgtg gacgactacg tcacctcggg cacgggcacc
     7801 ctcgacgagg tcatggagcg cggcttcagc cacgggtggg gagcgtcggc ggccaaccgg
     7861 gagctcgtgc gctggatgcg cgcgtacaac gacggccggg ccccggccga gcggctgcgc
     7921 ttcgccggtt gcgacggccc gctggagatc acccacgccg cgagcccccg gcggcccctc
     7981 accgcgctcc acggctacct cgcggcccat gtggacgccg acctgctgcc ctgcaccgcc
     8041 gacaccctcg acggcctgct cggggccgac gaccggtgga ccgatcccgc cgcgacgacg
     8101 gacccgtccc ggtccgtggg ccggtcggcc gaggccaggg agctgctgct gctcgccgac
     8161 gatctcgtgg cgctgctcga cgcggagacg ccgcgcctga tcgccgcgtc cgcacgagac
     8221 ggctgggacc gggcccgcct gtacggccgc gccgccaccg gcctcctgcg ctaccacttc
     8281 tggctggccg acacgtcacc gggacgcatg acaaggctgc tgggcctgcg cagctcgatg
     8341 atcgccgcca acctcctcgc cgtcgccgag cggggtccgg cgctggtcca cgcccacaac
     8401 ctccacttcc agcggcacag gagcacgatg cggctgggcg agctgccggt ggagtggtgg
     8461 agcgccggcg cgatcgtccg cgcccatctg ggcgaggagt tcgcgttcct ggccacggcc
     8521 ctcggcacga tgcggcacca gggagtggag accccgcccc cggacaccgt cgaggggctc
     8581 ctgtacgcgc tcccgcagga gcgctgcgtc gtcggcaccg gccggctggc cgccgccctc
     8641 ggcggcgccg cgctcgcggc ccgcacgtcg ccctggttcg gctacttccc gctggatccg
     8701 gagcagctga cggggagcga cgggatcgtg ttcgtcaagg acgtcccgcg gagctaggcc
     8761 gcctcccgcg cctcggcatc ctggcgtggg cccgcagcag cagcggcatc agcaggtaca
     8821 ccaccgtcgg cacgacgacg ccggtcagga tcagcgtgcg caggggcatc ggcagaggcg
     8881 cgatggccgg cccgagcagc agctggacca ccatgatcat cgaatagacc gccagccagg
     8941 tgagcagcgc ccgatggtgc accgacggcg gggcgggcgc gacggcggcg ggcctcgccg
     9001 gcctcgcggg gctggcgggg gcggcggagg tggcatgggc ggcttgggcg accggcatgg
     9061 cgatcccctc tctgggacgg gtgagggctc tgggcgagcc ccgaatccaa ctcgatggtt
     9121 ggagtttgcc acacccgcgc cgaaaactcc aaccgcccag ttggagaatg tcgtatgctg
     9181 aggtcatggc atgggacacc gcccgaacca ggcaactcct cctcgacgcc gccgtcgagg
     9241 agttcgccga gcacggcccg cagggcgccc gcgtcgaccg ggtcgcggcc aaggccgggg
     9301 tgaacaagga gcgcatctac cagtacttcg gcaacaagga ccagctcttc ggcgccgtgc
     9361 tcacccagga gctcgaacgg ctggccgccg ccgtccccct ggacgccgcg caggccgccg
     9421 acctcggcgg gtacgccggg cgggtcttcg actaccacag ctcccacccg cacctggtgc
     9481 ggctgctgca ctgggagggc ctgcacgccg gcgacgccga ggtccccgcc gaggcggcca
     9541 ggaccgccca ctacgccggc aaggtcgccg cgctggccgc cgcccaggag gagggctccc
     9601 tcaccggcgc gctgccgccg gccgacctcg tgtacgcggt gatcgccctg gccggctggt
     9661 ggttctccac cccgcaactc gcccgcatga tccgggccgg cgtcccggac gacagccccg
     9721 ccgcccggcg cgaagcgctg atccgcctcg tccgcgccct cgtcgcctga ctcctcggtc
     9781 ccgcgcctgc ccgggcccgc gcgagcaggg acgtggcgca gggcaggagg atcacccacc
     9841 cgttgccacc gccaccgccc ttcctccgtg gcggctcggc aggaacccct tccgctccgg
     9901 gagggttcct gagccgcgcg gccacgtcga cgaacggcgg acggagcctc cgaggagctg
     9961 ggaaatcgct ctccggcgca ggaaagtctc accgggaggc tcagccgacc gggaggcagt
    10021 cggggccccc gtacgccagc cggcggaaga acgtcacgac gccggtcagt ccctgcgccc
    10081 acgagagcga gcgggcggga gggtcgccgg gcgcgaagaa ggtggggtgg aggggcgagc
    10141 cggcgctccg gagcaggaga tgagtggcca ggtcgtacgc cgccgcccga tgacgctccg
    10201 actgttccag ctcggccagg gtcagcaggt agttgccgac gccggccacg ccgcagcact
    10261 ggccgagcgc gctcaggcgc gacatgcggg cgacgcacac gtcggctccc cgacgggcga
    10321 ggtcggccag ggccgggtcg cccagcacct tgctcgcgtg cagcagcgtc ggcccgaccc
    10381 cggcgaggcc gcggcaccag gacatggtca tcggttcggc ggccgggtcc tccgcctcgc
    10441 gtaccaggac ccgggcgcgt tcggacagga ggcgcacgcg gtccgcggcg gcttcgagca
    10501 cccacgactc gccggtctcc tcggccaggc cgagcagcaa cgcggtggtg ccggccaggc
    10561 cgtgcgcgcg tccggccgtc acgtcggcct cgcccggcct ggaggcgcgg ggcagcggtc
    10621 gttccgccac gacggcccgc gcgcagcgcc gcgccgcctc caggtcggcc gggtcgccgg
    10681 tgaggcggtg gaagtacagg tgcccgaggc cggcgcccgc gtccccgtcg gtcaggtcgg
    10741 cggcctccgg gcgccactcc ggcggcggca ggctcctgcc cggccggccc cccgccgggc
    10801 tgatgccgcg gtcacccgcc tcctggagga agacgtccgt cccggtcacg ccggtgaaca
    10861 ggccgggctg cggcgtcaac ggcgccgtga cgcgtacggt gaagtccacc agctcgcgca
    10921 gcttccgctc cgcggccggc cggtgccggt ggtgcagcag ctccaggccg atgcccgcgc
    10981 tgccgctgta gacgctcgcg tcgttggcgg ccttcgtgcc ggccggagcc tccaggacgc
    11041 cgtccaccag atcgagcaga tcgcccacga ggttgtccag cacctcggcg gccacgtcag
    11101 cggtgaccac gggcgcggcg accaccggcc cggcgaccac gggcgcggtg accacaggcg
    11161 cggtgaccac aggcgcggtg accacaggcg cggtggcgac aggcgcggtg gcgacaggcg
    11221 tcggcgggga gaccgtccgg cggtcgtccc ctgacgcgag ccgcagcacc gcggcgcgcg
    11281 cacgttcctc gtcgccgagc aggtccacca cggcggacat cgtccccgac ggcgtcgggc
    11341 cgtggtaccg cgagaccgtc tgcagcgccc gcgtcctcgg cagctcgggg tcgtcgccca
    11401 gggtcaccgg gtggagccct gtcgccgcgt acaccagggt catgccgagc gcgtggaggt
    11461 cgtcggcggc tcgcggcggc tcgccgcgca cctgccgcgc gggggcgtag cccggtgtca
    11521 gcccggacag atgcagcccg tcgtaggagg cgagtccgaa gtcgatgagg ctggcgccgt
    11581 caccgatcac gacgttggcg gcggacaggt cccgcatcat gacgccgcgt tcgtgcaccg
    11641 cggtgagaat ccgggccagc tcgcccgcca gccggtcgag gctccgcgcg cccgcgccgg
    11701 gtcctgtccg gtacggaccg ttccgccgca cgtcctcggc cagggtcgcc gggccgcggt
    11761 cggtggtgac caggaactcg tcgtcgccgt accggaagtg gtcgaggaag cgcggcacac
    11821 cggcgactcc gtcgagggcc tccaggacgc ggcgctcgtt gcgcagccgc agccggccgt
    11881 cgttgccgtc gccgtgttcg gcgacgaagg cgcgcgcctg cttgacgacc acccgcccgc
    11941 cggtccgctc gtcgatcgcg cggtagacgt tgccctgggc ggcctcccgg atcccgacga
    12001 cgacgcggta gcgaccgctc agcagcaggt cgtcgccgga gcggccgggt tcgggccgag
    12061 cgccggtgaa cgggtcctcg acccacgacg gttgccggta gctgagcccg gcggcctcgt
    12121 cgaactcctc gccggcgggc ccgcgcagct gtgtgatgga ctgtccgcgc acgtcggtgc
    12181 tccgccgggt gacgaaccct ccgtaccggt agtacaccgg agcgtccgcg gacactctcc
    12241 ggtcgctgag cacgcgcggc ccttggtggc cggtcaatgt ccgggcgagc agcagcccga
    12301 cgtcacggac gcgatgctgg tcgggataga cggtgaacgc cttgccgacg ctctccggga
    12361 ccgtccggcc gtcgttcaac tcgtggagca cctgccgcga acgggccagc ttgaacacac
    12421 atccctcggc caccagcaag gggacgagtt tctccacgag cgcgggaaag ttcgaggcgc
    12481 gagaagatac gtgtaacttc catccgtggt ccggtaaaac ggccctatct ggcctgacaa
    12541 ccagccagac agagccgcct gtcaccgtgt ggtcagcgcc gacgcattgc ctgacgactt
    12601 gttccaccca gtcctgggaa cccgcctcgc acatcttccg ccagcccccg tctgggtgaa
    12661 ttccggtacg tccgggccac gccgaccccg gtgatcagca gattttcgag acgccaggtc
    12721 gcgtcaccgg gcagcggtcc tggtcgacct ggctctccca ccgctgctcg aactcgacga
    12781 ccggctccat cacgtcggtc ccggccactc ggggttccat cctcagaagt gccgacattg
    12841 cgtgtccctt ctgcccatta cagcctgtcc gatatcagcg caatgctaac agtcggggat
    12901 tccgtgtcaa gatctcttgc aatgcgttcg gcctgacacc gaccgatgac caagcgtgcg
    12961 gacggaacgt tccagacgcc ctggaaatgg cgtttctcat atgcacgaat tcgatttccg
    13021 caacggcgtg aaattctgtt cacctgtttc ggctgctagc cgggcgggct cgaatccgac
    13081 gccggttcca ggccgaggcg ggcggccagg cccgcggcgg cggccgacag ctcgggcggc
    13141 atggggcggc gggtcaccat gaacagggtg agcctgcccg ggatcgtcat cgccgcgatc
    13201 tcctcccccg gcccggcgta ggagacggcc ggcccgctcg gcaggacgat cgggcagccg
    13261 agcaggcggc ccatccgcac ggccgtctcc gccgtggccg cccgccgcgg ccgtccgccc
    13321 agctcggaga gccgccggtg cagcgcggcg gtggaggcgt cgtaggtgta cgcgaccacg
    13381 tcgagccccg cgaacggctt gcgcccggag ccgaggcgcg cccccgccgg gacgaggacg
    13441 accagccggt cgcgggccac gggcagcgcc gtcaccgtgg ccggcaaccg catctgatcg
    13501 gcgatcgcga cgaaggccac gtccatcgag ccctcgccga cccattcgac cagccgatcg
    13561 ccgtggtcgg cgacctggtg caccgtcacc tcgcccagca ggtcctccaa cgccgggaac
    13621 acccacgggg cgaggctgcc gaacgtgccc gccctgaggc tgcccgcgcg ggccgccgcc
    13681 cgggtgcgat cgaagatcgc ctccaggtgc tccagcacgt gtgccgcctc agcggcgagc
    13741 gcccggccgg ccggcgtcgg ccgcgctccg gtcgtgtccc ggtcgaagag ccgctcgccg
    13801 atccgccgct ccagcgcggc cagccgattg ctcgcggcgg gctggctgat gagcagttcc
    13861 cgcccggccg cgccgagcga gccgtgccgg acgagcgctt cgactagccg cagatcctcc
    13921 accgacggca atgacctcat aagccaacgt tatgagctca cggcacgatc cacgacctac
    13981 cccgaaattt cgccagattt caggattgct ccgtgacttc tcgccgcgac atcgccgcca
    14041 tgctcctgac cacgttcctc acctggatgg gacagcgcac caccgccgtg gcgctccccc
    14101 tcgtcgcgct cgccgagacc gggtccccct ggaccaccgg gctcgtcggc ggcgccgtcg
    14161 ggctgcccat gctgacctcg gcgtggtggg cgcgcggact gcggcaacgg ctgacgaccg
    14221 gccgcgccct cgccggcgtg ctcgccgtcc aggtggccgg actgctcgtc gtcccggtcg
    14281 gcgccgccct cggcaccgtc ggctcgatcc acctggccgc caccggcctg atcaccggct
    14341 gcgcgaccgc cgtgggggcg cccgcccagc gggcgctgct cgccgacctc tgcgaccggc
    14401 tgggcgcggg cgtcgccgcc cggatgctcg cctggcagga cttcgcccac cggagcacga
    14461 tgatcctggc cccgcccctg gccggctggg cgatcaccgc caccggcccc ttccacctgc
    14521 tctgggcgga ggcggcgggc gtcggcctgg gcgcggccgt gctgctgacg gtgcgcggcg
    14581 ccgcgacggc caccaccggc ggcgacgacg cgtccgcctc ccccggcggt gacgacgcgt
    14641 ccgccacccc cggcggtgac gacgcgtcgg cttcccccgg cggcgacgcg ccggcgctca
    14701 ggcacgtcct ggcccgtcac cccgagatac gccgcgccgt gacgatgtcg ggcgtcggcg
    14761 ggctcgtctg gttcgccttc accctcgggc tggcgatcct cggcgccgag accggccgtc
    14821 ccgggctgct catctcggcc ggcatgaccg gttacggcgc gggctccctc gtcggcgcgc
    14881 tcctggcgcc ggcggtcgtg ccccggctgc cggcgctggg caccatggcc accggatggg
    14941 tcatcctcgg ggcgtccttc atcgccctgc ccgcggtcac ctcgtcgctg ccgctgatcg
    15001 cctgcctggc cgcggccggc ggcttcgcca tgccgctcgg catcggctcg atgaaccggc
    15061 tgatcaccgt gcgcaccgac ggcgcggaac ggcgggccgc cttcgccgcc gagagcctgg
    15121 tgcacgacgg ggcggtgtca ctcggcctgc tcgccggagg ggcggtcatc ggcctggccg
    15181 gggcagggcc gacgctggtc gtcgcgggcg ccgcgcaggt cgccgtcgcg ctggtcgccg
    15241 gcccctggct gatccccgtc cccgctcgtg agccggtacg gtctaccctg caatgatcat
    15301 gatgaacgac gggagaacgg gcgcgatgga cgagcggcta ccggacgagg tcgtcctggg
    15361 catgatcgcc cggcggttgt ccgaggccat ggaccagccc tggcacgtca cgggagacct
    15421 ggccaagggc cccggcagcc tcgccgtggt gctcggcgag gaccacaccg gccaccccgg
    15481 tcatgtggac atcgacttcg tgctcaatgt cgaccggccc gggaacacca cgatcagcga
    15541 ctgcgccacg ggatacggca cgactcccga ggagaccgtg gagcgcgcga tcgagatctg
    15601 gctgggcacc accggcagcg ccctgctcga actcctcgcc caggacggct ccttcgccgg
    15661 gcactacgcc gccgacgacc ccgacgggtt ccccggctgg cacatgatcc acggcggcat
    15721 caccggctgg ggcatcggcg acgacttcca ggccgtccag cgctgggccg cggacaaccc
    15781 gctcgcgccc catctggccc cggcgctgcg gagctcgttc gaccgtgacc acctgatcgg
    15841 cgtcaaggcg ttcttcggca gcggcgggga ctccgagacc gccgagatcc gggtcgacgg
    15901 catccaccac gaggcggcct cggaggtgct ggccggcctg ccctggcccc ggccggccgg
    15961 cggcatgtcc tacgccagga cgttcctgct cctcgtgcac aacgagggag gcgacgaggg
    16021 acgcgagagg ggacgcgacg agacggcgtg acggcggtca ggaggcgacc gccgccggca
    16081 cgggctcctt cgcgggctgg gtgacggcca gcttgcgggc caggcgcagc cggtacgcgt
    16141 ccagcaccac cgccaccagg atcaccaggc cggtgatgat ctgccgctcg aagtcggaga
    16201 cgcccatgag cagcagcccg ttggtgagca cgccgagcag gcacgccccg aggaacgtgc
    16261 cggccatcga gccgcgcccg cccatcaggc tggccccgcc gatgaccacg gcggcgatcg
    16321 cgttcagctc gtagccctga cccaggatcg ggctggcgat gttgagccgg gccatgtaca
    16381 ggacggccgc gatgcccacc gtcagtccgg cgatcatgaa tgccgcgatc ttgatgcggg
    16441 acgtcttgtg gccggacagg cggaccgctt cctcgttgtt gccggtggcg tagatcagcc
    16501 gcccgaagac cgtgcgcgac agcacgaacc agccgatgcc cgccagcagc agcgcgaccc
    16561 agaacaccgc ggggacgccg agcagcgtga tggtgccgaa gtcgttgagc gcggcgggca
    16621 ggttgtagat ggtggccgcg tcggtgtacc gctcggcggc gccgcgggcg acgttgagca
    16681 tggccagggt gacgatgaac gacggcaccc gccactgttc cgacacgaac ccgttgatcc
    16741 agccgaccgc gccgccgacc agcacgctga ccaggatcgc gccgagcagt gtcacggcgg
    16801 agtgcgatcc ggccatcatc gtgccggaca cgaccgcgca cagcgccatc gccgagccga
    16861 ccgacaggtc gatgccgccg accaggatca cgaacgtcat gcccacggcg agcacggtgt
    16921 tcagggtgat ctgggtcatg atgttgcgca ggttctgctc ggtcgcgaag ttcggtgccg
    16981 cgatgacgaa gaagcccgcg agcactacca gggcgacgcc gatgccggcc tcgccgagca
    17041 cgagcctttt gatcattgtg tttcaccgtt cttgaggtag cccgagtagg cgagcgtgag
    17101 gatgtgctcg gcgtcgaagt ccggcctggc gacctcgccg gcgatcttgc cgcgggagaa
    17161 gaccaggatg cggtcgcaga cgcccatcag ctccggcagg tccgaggaga cgacgatcag
    17221 ggccttgcct tcggcggcca ggccgagcag cagctcgtgg atctcgtact tggcgcccac
    17281 gtcgatgccg cgggtgggct cgtccacgat caggatgtcg gagccggcgt tgagccactt
    17341 ggccagcacg accttctgct ggttgccgcc cgacagggtg cgcacgtgct ggccgacgcc
    17401 cgcggagcgc aggtgcaggc gccgcccgag gtcctcggac agggagcgtt cctggccgaa
    17461 gcgcagcagg agcccgcgca gcttggcgag cgtgacgttg gcgctgatcg gcaggtcgag
    17521 gacgaggccc tgcgacttgc ggtcctcggt gagcaggctg atgccgtgcc gcaccgcgtc
    17581 cttggggtgc cggatgtgca ccttctcgcc gtaaagcttg atatttccgg acacggccgg
    17641 gtcggcgccg aagatcgcgc gcatcgcctc cgtacggccc gagccgacca gccccgccag
    17701 ccccacgacc tcgccccgcc gtaccgagaa ggagagcggc ccctcgaagc ccgcgacctt
    17761 gagctcgcgc acctcgatcg ccacctcgcc cggcgcggtc ggcggcttga cgggatactc
    17821 ctgcgccagg tcccgcccca ccatcagccg gaccaggtcc ggcgcggtca ccccggccat
    17881 ctcacgggtc tcgatgctgc gcccgttgcg cagcacggtg acccggtcgg ccagctccag
    17941 cacctcctga aggtggtgcg agatgtacac gatggcgacg ccgcgctcgc gcagcccgcg
    18001 caggatgccg aacaggcgtc ccgcctcgcg cgaggtgagc gtggcggtcg gctcgtccat
    18061 gatgagcagc ttggagtcgg tggagatcgc cttggcgatc tccacgagct gcatctgcgc
    18121 gatgccgagc cgctcgaccg gcgtgtccgg cgcgacgtcc agaccgacct gctccagcag
    18181 ccgcgcggcg tccgcgcgca gccgcttccg gtcgacgacg cccgccgtgc gcggcagccc
    18241 gcgcaggaac aggttctccg ccacggtgag gtacggcagc agcgccagct cctggtggac
    18301 caccgagatc ccggcggcca gaccgtcggc cgcgccggcc ggggtgtacg gcacgccgtc
    18361 gaaggtcatc gtgccggcgt ccggcgcgtg gatcccggcc agagccttga ccagcgtgga
    18421 cttgcccgcg ccgttctccc ccaccagggc gtggatctcg cccgcgcgga tgtcgagatc
    18481 gaccccgtcg agcgccacca caccggggaa gcgcttgacg aggccggtga ccgtcatcat
    18541 ccgaggttgt ccttggtgat gagcttgatc tcggtcttct gccagccgct gaagttctcg
    18601 ccgccgatca tcttcatggc gtagtcgatg ccgttggcgg cctgctgcgc gccgtactgg
    18661 tcgagggtgg acacgacggt gccgtccttg acgtactgcg cgatggccgg gatgttgtcg
    18721 aacgaggcga ccttgatctg gcccttcttg ccctgctcgt cgatcgcctt cagcgcgccg
    18781 agcgccatgt tgtcgttgcc ggcgagcacg cccttgatgt tcgggtgggc ggtgagcatg
    18841 ttgctgaaga cggtgtgcgc ctcgttggtc tcccagtgcg ccgtcttgga gtcgacgagc
    18901 ttgagcccgc cctccttgac cgcgtcctcg aagccggcct tgcgctgagc ggcgttggcg
    18961 gcgcccgggt tgccctccag gatgaccacc tcggcgtcct tgccgacggc cttggccagc
    19021 tccatgccgg actgcttggc gccctcgcgg ttgtcggggc cgacgaaggg caccttgtcg
    19081 ccgatgccgg cggccttcat cgcgccctct tcgagctgga cgtcgatgtt gacgaccttc
    19141 acgcccgcgt cgacggcccg cttgagcggc gccaccagcg cccgcgagtc ggcgggggcg
    19201 atcacgatcg ccttggcctg ctgcgtcacg cacttctcga ccgcggcgac ctggttgtcg
    19261 atgtcggtct cgttctggat gccgacgacg ctgagcgtga ggtcgccgcg cttggccgcg
    19321 tgctcctccg cgcccttctg catctgctgg aagaactcgt tggccagcga cttcatcacc
    19381 aggcagacgc ctggcttctc acccggcttg ggggcggcgg ccggctcggc ggcggtgccg
    19441 ccctccttgc cgcaggcggt cagcgcgagg gccagaccgg ccacggcgac gatcttcttg
    19501 ttcatctggt gtctccttca gaagggaacg cccgcttgga ggacgacgtt cgcgtacggc
    19561 gtcgcctcac cggttcgcac gaccgcgcgg gcccggccgg tgagctcctt gagccgggtg
    19621 tgagggatgc gttgtgttct cgtggtgttc ttcagcagct cgtcgaggaa gccgggcggc
    19681 gactcctcgg cgacgtaggc ggcctcgacg acgagctcgc cgagcaccgc ttcgagtacg
    19741 gggaggaagg cgggttcgcc ccggcgccag acgaggtcca ccgtctcgac gccgggaggg
    19801 acgggcaggc cggggtcggc caccacgatg aggtcggtgt gtccggccgc ggacaggatc
    19861 tgcagcaggc gcggatgcca gaggccgtca tgacgcacgg gcgagcagcc tttccacctg
    19921 gccgccggtc ggcatggcgg tctgggcgcc gtgggcggtg gtcgccagcg cgccggccgc
    19981 gcaggcccgc cgtaccgcat ccgcgagagg caggccggcc gcgtgggcga gcgcgagctg
    20041 cgcgcagaac gtgtcgcccg cgccgaccgc gtccaccacg ggcacccgga acgacggcgc
    20101 ctcgcaggcg ccggaggcgt cccggccccg cgcgccgcgc ccgccgagcg tcaccaccgc
    20161 ggcgcgcggc ccgagcgcga gcagcccggc ggggtcggcg ccgcggcaca gggcgtccgc
    20221 ctcgctctcg ttgacgatca gcaggtccac cagggggagc aggtcgtcca ggccgtcggt
    20281 gtacggcgcg gcgttgagga tcaccggcac gccgtgggct cgggcctgcc gcgcggcggc
    20341 caggcaggcg gcgaccggga tctccagctg gagcaggagc gcgtcggcgc gggcgaggtc
    20401 gaggcccgtg gcgggggagc cggggccggc gaggtcgagg ccggtggtga cggagccggg
    20461 gccggtggcg gcggagcccg gatcggtgag gtggaacagg ctgttggcgc cgggggcgac
    20521 agtgatcatg ttctcgccgc cgtcctcgac gacgatcatc gccatgccgg tggcggcggg
    20581 cacccgccgt actcccgaga cgtccacacc ctcacccgcc acggcggcga gcagctcgcg
    20641 gcccagcgcg tcgtcgccga cctggcccac gaggcgcacc cgcgcgccca gccgggcggc
    20701 ggccacggcc tggttggcgc ccttgccccc ggcggcccgc accacggcgg cgcccgccac
    20761 cgtctcaccc ctgcccggca ggcgcgtcac ggggaccgtg agatccatgt tgaggctgcc
    20821 gacgacgacc agctccagct cccgcgccgt cccagccgtc gtcccgggcg ccgtttcagc
    20881 agcgttccga ggcgtcgtct caggcatcgt ccagcccacc cgcggggtcg gggcagccgc
    20941 aggagccgcg cctgatcagc gtggccgaca ggaccacgcg ctcgccgccc ggcgagtcac
    21001 cgatctgcgc cgccagcagc tccaccgcgc gcctgcccag ctcctcgatc ggctgacgca
    21061 tggtggtgag cgcgggcacg gtgtaggagg aggcggcgat gccgtcgatc gagcacagcg
    21121 cgatgtccgc tggcacgctc agccccagct cggccgcggc gcgcatgacg ccgatcgcct
    21181 gctcgtcgct ggtcacgaag agcgcggtgg gccggtcctc ccgcgacagg agccgccggc
    21241 cgctgaggta accctgccgc cgcccgtacg ggccgtgggc cagtggcatc gacgccgggt
    21301 cgataccggc ctcggtcagc gcccgcgacc agccggcgac gcggtcgacg gtcgggtgga
    21361 tgtccttcgg ccccgccacg caaccgatgc gccgctgccc gtgctccagc aggtgggtgg
    21421 tcgcctcgta cgcgccgccc tcgttgtcga gcagcaggtg gctggccggg gtgtcgtcga
    21481 gctcgcggtc gagcacgatg cacggcaccc cggacgcggc cagctgggac cgccaggcgc
    21541 gcgggccgtg ggcgggaatc aggatcagcc cgtccacctg gcggtcgatc agggtccgca
    21601 cgtaggcggc ctcgcggtcg tcgtcgtcca tcgcgttgcc gagcagcacc gtcaggccgt
    21661 tctcgaacgc gacgtcctcg atctcgcggg ccagctcggc gaagaagggg ttggcgttgt
    21721 ccgggacgac gagcccgatc gtgtgcgtgc ggctggtgcg cagcgagcgc gccacggcgt
    21781 tcggccggta gccgagctcg tcgatcgcgc gcagcacccg ttcgcgggtg tgcggggcga
    21841 cgttcctcgg cccgttgttg agcacgtagc tgacgacggc ctctgaggtg ccggccagcc
    21901 gcgccacatc gcggcgtgtg accactacgc aagtcccatc tactcgtgtt gacgcagtat
    21961 tcggtccggc ttccgcgaga agcaacacgt gtagatgcga cgttatgaag gcgttacgca
    22021 acgtttcgac gtgatcacgg atggcgggct ccggctgtgc gccggcctgc cgcggatcat
    22081 cgcgcggcac cgaggcaggc cccctacaac tgcgaattgg acgcctatat gcggacaaga
    22141 cgcataaatt cctggcgttt cacagaaatg caataggcga tatcctgccc ccttttgatg
    22201 ctcaattctt tgccctcccc ttatgaattt cgcgatgcca ttcctgtcgc gtcgggcacg
    22261 tagagaacga tcaccgcatt cacgtacgcg acggcatccc atggccgcgc gccgacgcgc
    22321 ggcaatcgaa cctctccgtc gatatctccg agccggccgg atccgctccg ccgcaggaga
    22381 aaccgtgagt gcgattcggc tgctcgtcgc cgtcatcgaa tcgcgcgtga tcgagcctct
    22441 ttcgtttctc acgcacgatc gacagggaag tcatgcggta tcaccgacac agcgtcatgc
    22501 tggccaccgc gatctgcgcg acggcagcca ccatgggcat cccggccgcg cacgccgaca
    22561 gcgccgctcc gttcgacatc cggccggtcc ggtcgcgggc cctcctgccc acgcaggccc
    22621 ccggcaagaa ggag
//
