LOCUS       NZ_JABWGO010000001     21068 bp    DNA     linear   CON 29-SEP-2024
DEFINITION  Nonomuraea rhodomycinica strain TBRC6557
            NODE_1_length_2417852_cov_21.4344, whole genome shotgun sequence.
ACCESSION   NZ_JABWGO010000001
VERSION     NZ_JABWGO010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nonomuraea rhodomycinica
  ORGANISM  Nonomuraea rhodomycinica
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 2417852)
  AUTHORS   Chanama,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2020) Microbiology, Mahidol University, Faculty of
            Public Health, 420/1 Ratchawithi Road, Ratchathewi, Bangkok 10400,
            Thailand
REFERENCE   2  (bases 1 to 2417852)
  AUTHORS   Chanama,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2020) Microbiology, Mahidol University, Faculty of
            Public Health, 420/1 Ratchawithi Road, Ratchathewi, Bangkok 10400,
            Thailand
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 26-MAY-2020
            Assembly Method                   :: SPAdes v. 3.10.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013363995.1-RS_2024_09_29
            Annotation Date                   :: 09/29/2024 04:09:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,940
            CDSs (total)                      :: 8,866
            Genes (coding)                    :: 8,758
            CDSs (with protein)               :: 8,758
            Genes (RNA)                       :: 74
            rRNAs                             :: 4, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 12 of 108
            Pseudo Genes (incomplete)         :: 99 of 108
            Pseudo Genes (internal stop)      :: 6 of 108
            Pseudo Genes (multiple problems)  :: 8 of 108
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:20:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1591126
            Orig. end                         :: 1612194
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABWGO010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Manee Chanama, Mahidol
            University.
FEATURES             Location/Qualifiers
     region          1..21068
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21068
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21068
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11068](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11068
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    296..311
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     misc_feature    complement(607..621)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 24.16"
                     /tool="antismash"
     misc_feature    608..622
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
     misc_feature    complement(1070..1085)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.87"
                     /tool="antismash"
     misc_feature    1071..1084
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.24"
                     /tool="antismash"
     misc_feature    1187..1205
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.21"
                     /tool="antismash"
     misc_feature    1193..1206
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.43"
                     /tool="antismash"
     misc_feature    complement(1199..1211)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.14"
                     /tool="antismash"
     gene            1228..1833
                     /locus_tag="HT134_RS07335"
                     /old_locus_tag="HT134_07325"
     CDS             1228..1833
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013130437.1"
                     /locus_tag="HT134_RS07335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07325"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_175599404.1"
                     /transl_table=11
                     /translation="MAGIRERKKQRTRRALIEAALRLFAEKGYEETTLAEIAAEADVST
                     RTFFSYFASKEDVLLHDIEIRMERTIAIVASHAPDEPLPDLLMRIVRDALAQVSEDEDY
                     DAEETRLRIRLVTTVPGLQARALRMVFANQLRLVQALEEAYRGRLGMVEAAAAVGALAG
                     AAKLAIVASVERGDSMQEALDAALRAAEISVRGLGSLT"
     gene            complement(1878..3737)
                     /locus_tag="HT134_RS07340"
                     /old_locus_tag="HT134_07330"
     CDS             complement(1878..3737)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HT134_RS07340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HT134_07330"
                     /product="hypothetical protein"
                     /protein_id="WP_175599405.1"
                     /transl_table=11
                     /translation="MLSTPVARTAHTSPPVRRTSRQTARGRSRWLGWALAGGWLAQVLL
                     RLWLYRYHTGPVANPDETGYLVAARWLAGGAGADLTGSTFYQGGYALLLVPAYWVTSDP
                     VTVYRLVAGIGSAAAATAFPLAYVVLRRLALGRREAVALAFVAGLSPALLLFSGLALAD
                     AVLPTLALGWLLATHDLARTGSPRAGAAAGALAGFATAVHLRGTVILAAYTLTVVALLV
                     VRRPARRAGRRLPLRAGAVALGVAGVVAAAGGALNRALASAVYPGGARDLSGMLAERLT
                     GLDGQAWALSGATGQLWYLIVSTWGLAGVGLAAAAVQLVRPGGPFARRVLAGTLLAVTL
                     GVAYASSAALPDEHRVGNYVYGRYLACVAVVWTLVGLATLSRAARAALTRRAAAPRPVP
                     AEDRAGALRRLHPAVRRMAAYAGAAAVLMAATGGVAAWYAGDRLRRYAFIAFDFPEVSF
                     LSGVRDSLDMVRATAAALVLLTCLTLAACLATFRPARRAARRPWTRALVPVVVVLAAVN
                     VAFTADLAPKAAPPAGPDWLPAPPPGRVALDDRVRWNVWVPLTYRVWWTRLERYDGARQ
                     APPAGACTAVVPPDAGPPPAGWTATGLGGERQGWTSWSGPGCR"
     misc_feature    3728..3742
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.95"
                     /tool="antismash"
     misc_feature    3824..3841
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.23"
                     /tool="antismash"
     gene            complement(3880..4815)
                     /locus_tag="HT134_RS07345"
                     /old_locus_tag="HT134_07335"
     CDS             complement(3880..4815)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890415.1"
                     /locus_tag="HT134_RS07345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07335"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_175599406.1"
                     /transl_table=11
                     /translation="MDRSGSERPELALHQLHAFAVLAEELHFGRAAERLGIAQPPLSQQ
                     IRRLERKVGHALFDRGPGGVTLTPAGYELLPAARRALGELAGGLDAARRAGRGEAGRIR
                     IGFAASLALTVLPRILGAYHDRYPGVEMEVREMTTAPQVAALCDGSLDVGLLREPPETD
                     GLVAEPLLSEGFVAVLPAGHPLAARRAVPVAALAGEPFVLLPREAAPTVHDRIAGLCRA
                     AGFEPRAGQRAVEWQTVCALVGAGLGVSLAPASVRRIRSAGVAYRRISPGGARTTVAAC
                     FRGEDPNPLVARFLRTAREQTSAPDGRPRP"
     misc_feature    4874..4890
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.06"
                     /tool="antismash"
     gene            4889..5275
                     /locus_tag="HT134_RS07350"
                     /old_locus_tag="HT134_07340"
     CDS             4889..5275
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890414.1"
                     /locus_tag="HT134_RS07350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07340"
                     /product="RidA family protein"
                     /protein_id="WP_175599407.1"
                     /transl_table=11
                     /translation="MTERRAIMSGSVFEERIGYARAVVDGDRVHVSGTTGFDYATMTIS
                     GDVVEQARQCLRNIGAALAEAGCSFADVVRVRYLLPDRADFEPCWPVLRECFGEVRPAA
                     TMLMCGLADPRMKIEIEVDARLPR"
     gene            5344..6327
                     /locus_tag="HT134_RS07355"
                     /old_locus_tag="HT134_07345"
     CDS             5344..6327
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540056.1"
                     /locus_tag="HT134_RS07355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07345"
                     /product="aldo/keto reductase"
                     /protein_id="WP_175599408.1"
                     /transl_table=11
                     /translation="MNYERQPYRRCGRSGLLLPAVSLGLWHNFGGGKPLDGQRAIIRKA
                     LDLGITHFDIADRYGPPLGAAESAFGQIFRADLRGLRDEIVVTTKGSNPMWDGPYGKGN
                     SRKHLLATLDRSLERLGLGFVDIFYLHRDDPETPLEEQAATLDHMVRTGRALYAGVSNF
                     SPERTAGIAALMRSLGTPLLVHQPPYSLLNRGIERSLLGVLEEEGVGCVVYSPLAQGLL
                     TDRYLDGIPEDSRAAEGRFLTADKVTPEVLAFVRALGELAAARGQSVAQLALAWALRDP
                     RVTSVLVGASSPEQLEANVAAVDRLGFTGDELAAVDRAAKESGLDA"
     gene            complement(6431..7279)
                     /locus_tag="HT134_RS07360"
                     /old_locus_tag="HT134_07350"
     CDS             complement(6431..7279)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131599.1"
                     /locus_tag="HT134_RS07360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07350"
                     /product="L,D-transpeptidase family protein"
                     /protein_id="WP_312888012.1"
                     /transl_table=11
                     /translation="MRARRLPGMAALVTAGVVVLTGFGTGPAAAAPTGTPALQAATTTP
                     TKTPTTNPTTTNPTTTAAAVTAEAPRKTLRLGAKGEAVTWLQRRLAELGYQPGRADGRY
                     GGTTLAAVWAFQKVNGIAPTSTVAARTWRALESPRAPKVLVPNGRPTRAEVNLTKQVMV
                     LYVGGQPKLITHISSGSGVAYCEAAVWQGKKQRFCGSARTPTGDYKTTWRKSGWHTSYL
                     GRLYNPIFFNGGIAFHGALSVPLYPASHGCVRMPMNVAEVLPGMLGTGVPVHVRGAFHR
                     A"
     misc_feature    complement(7298..7307)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 12.85"
                     /tool="antismash"
     gene            7375..7923
                     /locus_tag="HT134_RS07365"
                     /old_locus_tag="HT134_07355"
     CDS             7375..7923
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017624154.1"
                     /locus_tag="HT134_RS07365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07355"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_175599409.1"
                     /transl_table=11
                     /translation="MSEKSPDAQHTEPSAPPTAAELAARSTGLPANAVIVQGALRELGA
                     AGEIVVLPEKAPTAATAAAQLGCEVGAIANSLVFDADGAPLLVMTSGAHRVDVELVART
                     AGVRSVRRATPEFVRQATGQPIGGVAPVGHPSPIRTLVDTWLSKYDVVWAAGGHPHTVF
                     PTTFDELVRITGGTPVDVE"
     gene            7934..8551
                     /locus_tag="HT134_RS07370"
                     /old_locus_tag="HT134_07360"
     CDS             7934..8551
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131597.1"
                     /locus_tag="HT134_RS07370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07360"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_312888013.1"
                     /transl_table=11
                     /translation="MIEFRGAGPAEFDERLDTVIDIYTAAMRPPADQITGRRSIMRNHG
                     MYPRFQCYFAELRGEPAVPVPVPWPGAGPGAGPVRRGAAKVVGFAYGFHGAPGQWWHDV
                     VYRALEERSGPRVADAWLGDAFELAEIHVHPDYQGKGIGRAMITTLCAGRAERSAVLST
                     HDRPTAARHLYRSMGFTDLLSRFVFPGGYEEYAIAGRPLPLN"
     gene            complement(8987..9910)
                     /gene="metF"
                     /locus_tag="HT134_RS07375"
                     /old_locus_tag="HT134_07365"
     CDS             complement(8987..9910)
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291497.1"
                     /locus_tag="HT134_RS07375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07365"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_175599410.1"
                     /transl_table=11
                     /translation="MALGRPSVLPDRVPTVRELLASGGRSFSFEFFPPKTDEGERQLWR
                     AIRELESLRPTFVSVTYGAGGSTRDRTVDIVERVAHDTTLTPVAHFTAVNHSTRELRHL
                     VGRFADAGVRNILAVRGDPPGDPTGEWVRHPEGVLYAEELVRLIRQAGDFCVGVAAFPY
                     KHPRSPSIDSDTEFFVRKCRAGADYAITQMFFEADDYLRLRDRVAARGCDTPIIPCIMP
                     VTQMSTIARSEQLSGAPFPPALAARFEAVADDPAAVRQLGIEHGAELCQRLLDEGAPGI
                     HFITFNRSSASREVFQLLSRPEPVAV"
     gene            10001..11068
                     /locus_tag="HT134_RS07380"
                     /old_locus_tag="HT134_07370"
     CDS             10001..11068
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889490.1"
                     /locus_tag="HT134_RS07380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07370"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_175599411.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.2e-47, bitscore:
                     156.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTEAASMDTLREQVDRCLREFVDRQLPLTGAPELEPLRLAAKEL
                     LAGGKRLRPAFCYWGWRGAGGADLPGVYQAAASLELLQASALVHDDVMDKSDLRRGMPS
                     AHRRFEAMHADAGWHGSAEQFGMGAAILLGNLLLIWSGEMWRGSGLPPESLAGAQPVHD
                     HMRTELMCGQYLDLLEQAHGENTFESALRVALYKSGKYSVEQPLRLGLALAAGGLTPWM
                     DELCTTYGTRVGIAFQMRDDILGVFGDPAATGKPAGDDLREGKRTMLVARTLAAATPEQ
                     AALVRSLLGDPGLDDRGVAALREVIEDTGALKECEELIGAYLTEALACLDQAPITAEAR
                     SALAELAVAATSRQA"
     gene            complement(11282..11923)
                     /gene="thiE"
                     /locus_tag="HT134_RS07385"
                     /old_locus_tag="HT134_07375"
     CDS             complement(11282..11923)
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541674.1"
                     /locus_tag="HT134_RS07385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07375"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_175599412.1"
                     /transl_table=11
                     /translation="MPRPSLSDARLYLCTDGRRARGDLAEFLDAVLAGGVDIVQLREKG
                     LEAREELALLEVFRDACDRHGKLLAVNDRADVAHAARPDVLHLGQDDLPVRVAREILGD
                     DVLIGRSTHSAAEASAAAVEEGVDYFCCGPTWPTPTKPGRPAPGPPLLRHAAGLGTDRP
                     WFAIGGIDLGNLDEVMAYGATRVVVVRAITEADDPGAAAAEFAKRLGATR"
     gene            complement(11901..12275)
                     /locus_tag="HT134_RS07390"
                     /old_locus_tag="HT134_07380"
     CDS             complement(11901..12275)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541673.1"
                     /locus_tag="HT134_RS07390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07380"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_175599413.1"
                     /transl_table=11
                     /translation="MTLSVAQIDRDTEQLVNEWLTLPEVAERMQLSLGRTKQLLKDHKL
                     LGVRRGSGGPHVPAVFLDGNDVMKGLPGTLTVLQDAGYDDVEALRWLFTPDDSLPGSPI
                     EAIRAGRHTEVKRRAQALAF"
     gene            complement(12306..13469)
                     /locus_tag="HT134_RS07395"
                     /old_locus_tag="HT134_07385"
     CDS             complement(12306..13469)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853358.1"
                     /locus_tag="HT134_RS07395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07385"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_312888014.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.6e-47, bitscore:
                     158.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRVVVAGAGLAGVRSVEALRARGFEGEIVLLGQERHRPYDRPPL
                     SKAVLLGTSDSSFVDSDLATLEVDFRPGVSATGLRAGVVETSEGDLPYDGLVIATGADP
                     ITLPGDGQQHVLRTLDDALELRARLVRGARVVVIGAGWIGAEVATAARRAGCEVTVVEA
                     GPAPLSHAVGAELGARTLPWYDGIDLRLGTMVASVDEGGVRLVDGEFLEAHVVVTGVGV
                     RPAVEWLAGADIDLHNGVVADEHLRASLPGVVAVGDCAAWWSRRYGTRLRVEHWDTALG
                     APEVAAATLLGEDAVYDPVPYFWSEQFGHMVQYAGHHPAGSRLLHRGGPEGKWSACWLT
                     EDDTLAAVLAVDRPRDLVQGRRIIDAGHRMDPERLVDPDVPLRDCVV"
     regulatory      13528..13644
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(13601..13614)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            13634..14932
                     /locus_tag="HT134_RS07400"
                     /old_locus_tag="HT134_07390"
     CDS             13634..14932
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017541360.1"
                     /locus_tag="HT134_RS07400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07390"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_175599415.1"
                     /sec_met_domain="DAO (E-value: 3.4e-68, bitscore: 227.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELIVGGGVVGLSIAWRLSRAGRPVTVVDPAPASGASHAAAGMLA
                     PVSEVSYTEEPLLRLGVASLRRWPSFAAELAADAGLPPGVLSPSNGGSGGPSNGGTGAP
                     SNGGSGAPSYGLDFRADGTLDVAFGADDLAALDELAAFMTKLGLPVERLTGRECRRLEP
                     MLAPSVRGGLLAPGDAWVDPRRVTSALLAALERRGVPVVRARVSRLLRASQGPQEGAVV
                     GVELDEAAGGGAVPAELRADGVVLAAGVWSAELAGVPVRPVKGQIMRLRSAEPLLSRCV
                     RGMVHGTPVYLVPRGDGELVVGATQEEMGFDTRVTAGGVYELLRDARELVPGVTELEVA
                     EVVAGLRPGTPDNLPLIGPSGTPGLTLATGHHRGGVLLAPLTAALLQGEEPELAALCSP
                     ARHRPDPASAGHRDPRGPAAPPYDETSGSKEMG"
     gene            14929..15129
                     /gene="thiS"
                     /locus_tag="HT134_RS07405"
                     /old_locus_tag="HT134_07395"
     CDS             14929..15129
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541670.1"
                     /locus_tag="HT134_RS07405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07395"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_175599416.1"
                     /transl_table=11
                     /translation="MKVTINGSPREVPDGTTVAQAVRILTTATTGVAVAVNDEVVTRGS
                     WDTTALGDSDRVEVLTAVQGG"
     gene            15122..15877
                     /locus_tag="HT134_RS07410"
                     /old_locus_tag="HT134_07400"
     CDS             15122..15877
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541669.1"
                     /locus_tag="HT134_RS07410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07400"
                     /product="thiazole synthase"
                     /protein_id="WP_175599417.1"
                     /transl_table=11
                     /translation="MDDLIIAGEKFSSRLIMGTGGAPSLEVLDQALAASGTELTTVAMR
                     RLDPSARGSVLDVLRRRGIKVLPNTAGCFTAGEAVLTARLAREALGTNWVKLEVIADER
                     TLLPDPIETFDAAERLVADGFVVLPYIGDDPALARRLEQAGCAAVMPLGAPIGSGLGIR
                     NPHNIELIVEAAGVPVILDAGIGTASDAALAMELGCDAVLLATAVTRAQRPDLMAAAMR
                     SAVQAGRLARQAGRIPRRRYAEASSPMTP"
     gene            16172..18352
                     /locus_tag="HT134_RS07415"
                     /old_locus_tag="HT134_07405"
     CDS             16172..18352
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541668.1"
                     /locus_tag="HT134_RS07415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07405"
                     /product="PASTA domain-containing protein"
                     /protein_id="WP_312888015.1"
                     /sec_met_domain="Pkinase (E-value: 1.9e-50, bitscore:
                     168.7, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 6.2e-06, bitscore: 23.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTTTADPLVGRTLDGRYRIESRIARGGMATVYLALDVRLDRTVA
                     LKVMHRSLAEDPAFVRRFIGEAKSVASLSHPNVVHVFDQGTDGDVVYLSMEYVPGRTLR
                     DILNERGRLPAREALEILIPVLAALGAAHQAGMVHRDVKPENVLMTADGRVKVVDFGLA
                     RAIEATNQTRTGMMIGTIGYMSPEQVTTGRADVRTDVYAAGIMLFELLTGQPPYEGETP
                     MSVAYRHVHDTVPAPSSLNPEVPPVVDALVAHATAREPDARPADATAMLVEAVEVHRQL
                     PRLTAPGVPHTGARYSLPGTGPHAPSGPHAPSGSLPVPTAQLPSGVHTSPAGGHLPGPR
                     TGPHSGAQPTGPAHGGYGPQPASQPGNYGPQPASQPVGAGSPGMTVAMPQVPPGGAALP
                     NPTMIQPRAETPAEPPSGRRRGFRPSWIIVALAVVMVAAIGLTGWYVSRPQYVTVPADL
                     VGRPVSLVEAKLASGGLKVKVAQGRHDDKTDEGMVLSLDPVGGQEVEAGTTVTLVPSLG
                     PKLVVVPKVAGMSADDARAAIAKAGLTVGTVRRLANPDVARDTVIRTSPLVGEKLKEGT
                     KVSIYVSAGLTMPDVAKMPKDQAAAFLQEQGFQVQVNEVDDDAEPCTVIAQSPKAGAEV
                     DRGAAAMVTVARCQSDFWDWWKGDNEAREDQEHQLVPAVMGKNVNDARQELQQLGWKVR
                     VLKLGKGSGVVRFQRPLPNSERPPGSEVILWH"
     gene            complement(18365..19330)
                     /gene="alc"
                     /locus_tag="HT134_RS07420"
                     /old_locus_tag="HT134_07410"
     CDS             complement(18365..19330)
                     /EC_number="3.5.3.4"
                     /GO_function="GO:0004037 - allantoicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="alc"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018655441.1"
                     /locus_tag="HT134_RS07420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07410"
                     /product="allantoicase"
                     /protein_id="WP_175599418.1"
                     /transl_table=11
                     /translation="MAPERPSAGFTTLPDLALRTLGGSVVAASDESFAEKESLIRPGRP
                     AFRPQTFGDKGQVYDGWETRRRRGPGHDWAIVRLGLPGAVRGVVIDTAWFTGNHPTHAS
                     VEAAAVDGHPSPAELLDARWTEIVPKVALRGDAEHPVEVAGDVRYTHVRLNMYPDGGIA
                     RLRVHGEARPDLSVYDGLSLDLAALHNGGLVTACSNAYYSSPLNVIAPGLARHQAEGWE
                     TARRREEGNEWLVIRLAGRGVVRLAEIDTTNLIHNAPAAVTLTGLDGDREVELLPRTRL
                     QPDTPHRFRLAHVDPVTHVRVDIHPDGGLARVRLHGHLTG"
     gene            complement(19331..20635)
                     /gene="allB"
                     /locus_tag="HT134_RS07425"
                     /old_locus_tag="HT134_07415"
     CDS             complement(19331..20635)
                     /EC_number="3.5.2.5"
                     /GO_function="GO:0004038 - allantoinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0050897 - cobalt ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="allB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541666.1"
                     /locus_tag="HT134_RS07425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HT134_07415"
                     /product="allantoinase AllB"
                     /protein_id="WP_175599419.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 2.4e-23, bitscore:
                     79.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDLVVRSRRVVTPEGERPAAVAVRDGRIAALHPYEAPLETAEDV
                     DLRALPLLPGLVDTHVHVNEPGRAHWEGFASATRAAAAGGVTTIVDMPLNSVPPTVTPD
                     ALDAKLRAAEGRCHVDTAFWGGAVPGNVEHLRPLHERGVRGFKCFLSPSGVEEFPPLRP
                     DEARRAMTEIAGFGGLLVVHAEDPALLAEPAGPTYREFLESRPGAAERSAVELVIRLAE
                     ETGARVHVLHVSSAACLGPLEEARARGVPVTAETCPHYLTLAAEQVPEGDTSYKCCPPI
                     RDGANRDRLWEGLARGVLDCVVSDHSPSTADLKVPDFAAAWGGVASLQLGLPAVWTEAS
                     RRGYGLTDVARWMSARPAAIAGIPRKGAVEPGNDADLVAFDPDAANPVDARALHHRNPV
                     TPYHGRTLRGAVLTTWLRGRPADGEPHGVFLLGDK"
     misc_feature    complement(20989..21004)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.6"
                     /tool="antismash"
ORIGIN
        1 cagcccgggg aagcggcgca gcagcgccgg atagccgatg cgcatctcga tgcgcgccag
       61 ctgctggccg aggcactggt ggatgccgtg gccgaaggtc aggtgaccgc cggcgggccg
      121 ggtgaggtcg agggagtcgc cgccggggaa gcgggccggg tcgcggttga cgacgggcag
      181 gctgaaggcg accgcctgcc ccttgcggac cacgacgccc tccacctcga cgtcctccag
      241 cgcggagcgg atcgggccga tgtggatgat cgtcaggtag cgcagcagct cctccacgcc
      301 gttgtcgacc acggacgggt cgtcgcgcat ggcggcgagc tggtccgggt tgcgcagcag
      361 cgcgtacgtg ccgaggccga gcatgttcgc ggtcgtctcg tgccccgcca cgagcaggag
      421 gaacgcgacg ccggtcagct cgtcgtcggc cagctcgccg ccctggacca ggccgctgat
      481 caggtcgtcc cggggctcgg cccgcttgcg ctggatgagg tcgtacaggt agcccgtcat
      541 gctcctcatg gcgtcgatga cctcgtcggc gccgctctcc agcgcgagca gcagcctgga
      601 gtcgcgctgg aagcgctccc tgtcctcgta cggcacgccc agcagctcgc agatcaccag
      661 tgacgggatg ggcagcgcga actgctcgac caggtcggcg ggcttgccgg cggcctccat
      721 ggcgtcgagg cgggcgcgcg tgatctcctc gacgcggggt tcgagctgct tcatccggcg
      781 gaccgtgaac tggccggtga gcagcttgcg gtagcgggtg tgctcgggcg cgtccatgcg
      841 caggaagaac cccggcaccg cgaactcctt gccgcgcagc ttctcggcca cctcggcgcg
      901 ggcggggatg gtcggatggg tgtactccgg ccggttgctg aagcgggggt cggcgaggat
      961 ggcgcgggcg gccgtgtaac cggtgaccag ccagccctcg tgcccgtcgg cgaaggtcag
     1021 ccgatggagg ggcgcctccc cgcccagttc ggcgatccgc tccggcgggt cgaacgggcg
     1081 ttcgcggtcg gtggtcatga tgagctctga catccgtggc tcctagcggt cgccttgcac
     1141 agaacttccg ggtcaccccc agaaaacatc atcgaatgca aactttcaat ggatgtaaat
     1201 ccaaaatgcg tgcagtacag ttccgccatg gcgggcatca gggagcgcaa gaagcagcgc
     1261 acgcgccggg cgctgatcga ggcggcgctc cggctcttcg ccgagaaggg ctacgaggag
     1321 accacgctcg cggagatcgc ggcggaggct gacgtgtcga cgcgcacgtt cttcagctac
     1381 ttcgcgagca aggaggacgt gctcctccac gacatcgaga tccgcatgga acgcaccatc
     1441 gcgatcgtgg cgagccatgc ccccgacgag ccgcttcccg acctgctgat gcggatcgtg
     1501 cgcgacgcgc tggcccaggt gtccgaggac gaggactacg acgccgagga gacccggctg
     1561 cggatccggc tcgtgacgac cgtcccgggc ctgcaggcgc gggccctgcg catggtgttc
     1621 gccaaccagc tccggctcgt gcaggcgctg gaggaggcct accggggacg gctcggcatg
     1681 gtggaggccg cggcggcggt gggcgcgctc gcgggcgcgg ccaagctggc gatcgtggcc
     1741 agcgtcgagc ggggcgactc catgcaggag gcgctggacg ccgccctgcg cgcggcggag
     1801 atctcggtgc gcggcctcgg ctcgctgacc tgaacgccgc gggccggcgg tcccgcgccc
     1861 ggtcgccgcg ggtccgttca gcggcagccg gggccggacc agctcgtcca tccctggcgc
     1921 tcgccgccca ggcccgtggc ggtccagccc gccgggggcg ggcccgcgtc cggggggacc
     1981 acggccgtgc aggctccggc tggcggggcc tggcgggcgc cgtcgtaccg ctccagccgg
     2041 gtccaccaga cccggtacgt gaggggaacc cagacgttcc accgcaccct gtcatccagg
     2101 gccacccttc cgggaggcgg ggcgggcagc cagtcgggcc cggcgggagg ggcggccttg
     2161 ggggcgaggt cggcggtgaa ggcgacgttg acggcggcca gcacgacgac gaccggcacc
     2221 agcgcgcgcg tccacggacg gcgcgcggca cggcgggccg gccggaacgt ggccaggcac
     2281 gccgccaggg tgaggcaggt cagcaggacg agggcggccg ccgtggcccg caccatgtcg
     2341 agggagtcgc gtacgccgct gaggaaggac acctcgggga agtcgaaggc gatgaacgcg
     2401 taccgcctga gccggtcgcc cgcgtaccag gccgccactc ccccggtggc cgccatgagc
     2461 acggccgccg cccccgcgta cgccgccatg cgccgcacgg ccggatggag gcggcggagg
     2521 gctcccgcgc ggtcctcggc gggcacgggg cgcggggcgg cggcgcggcg ggtcagggcg
     2581 gcgcgggccg ccctggacag ggtcgcgagg cccaccagcg tccacacgac cgccacgcac
     2641 gccaggtacc ggccgtagac gtagttgccc acccggtgct cgtccggcag cgccgccgac
     2701 gacgcgtacg ccactcccag ggtgacggcc agcagcgtgc ccgcgagcac gcggcgggcg
     2761 aacgggccgc ccggccggac gagctggacg gccgccgccg ccaggccgac gcccgcgagg
     2821 ccccaggtgc tgacgatcag gtaccagagc tggccggtgg cgcccgacag cgcccacgcc
     2881 tggccgtcga gcccagtgag gcgctcggcc agcatcccgg acaggtcacg ggcgccgccc
     2941 gggtacaccg ccgacgccag cgcgcggttc agcgccccgc cggccgccgc gaccaccccg
     3001 gcgacgccca gggcgacggc cccggcccgc agcggcaacc gccggcccgc gcgccgcgcc
     3061 ggacggcgga cgaccaggag ggccaccacc gtcagcgtgt acgccgcgag gatcaccgtc
     3121 ccccgcaggt ggacggccgt ggcgaagccc gccagggccc ccgccgccgc tccggcccgc
     3181 ggcgagccgg tgcgcgccag gtcgtgcgtg gccagcagcc agccgagcgc cagcgtgggc
     3241 agcaccgcgt ccgccagcgc cagccccgag aacagcagca gcgccggcga cagccccgcc
     3301 acgaacgcca gcgcgaccgc ctcccgccgc cccagcgcga gccgccgcag cacgacgtag
     3361 gccagcggga acgccgtggc ggccgccgcc gagccgatcc cggccaccag ccggtagacc
     3421 gtgacgggat cggacgtcac ccagtacgcg ggcacgagca gcaacgcgta gccgccctgg
     3481 tagaacgtcg aacccgtgag gtccgccccc gctcccccgg ccagccagcg ggccgcgacc
     3541 aggtagcccg tctcgtccgg gttggcgacg ggaccggtgt ggtaccggta cagccacagg
     3601 cgcaggagca cctgggccag ccagccgccc gccagggccc accccagcca cctgctgcgc
     3661 cccctggccg tctgcctgga cgtccgcctg accggtggcg aggtgtgcgc ggtgcgggcc
     3721 acgggcgtgg acagcatgtt cccccctgct cggcgcccgg gtgtctcccg agctcagagc
     3781 aggcagtcca gcaaaagccc gctaaccggg ccgtcaccac atgtggttat acgggcgtta
     3841 tgtcgggcga cccggcgcgg aagccgccgc gggccggcct caggggcgtg gacgaccgtc
     3901 cggagccgag gtctgttcgc gggccgtccg caggaagcgg gccaccagcg ggttcgggtc
     3961 ctcgccccgg aagcaggccg cgaccgtcgt gcgcgcgccg cccgggctga tcctccggta
     4021 cgcgacgccc gccgaccgga tgcgccggac gctcgccggg gcgagcgaca ccccgaggcc
     4081 cgctccgacg agcgcgcaga ctgtctgcca ctccaccgcc cgctgcccgg cgcgcggctc
     4141 gaagccggcc gcccggcaca gcccggcgat ccggtcgtgg accgtgggcg ccgcctcgcg
     4201 cggcagcagc acgaacggct cgcccgccag ggccgccacc ggcacggcgc gccgggcggc
     4261 cagcgggtgc ccggcgggga gcacggcgac gaagccctcc gacagcagcg gctcggccac
     4321 caggccgtcc gtctcgggcg gctcccgcag cagccccacg tccagcgagc cgtcgcacag
     4381 cgccgccacc tgcggcgccg tggtcatctc gcgcacctcc atctccaccc ccggataccg
     4441 gtcgtggtac gcgccgagga tccgcggcag cacggtcagc gccagcgagg ccgcgaagcc
     4501 gatccggatg cggcccgcct ctcccctgcc ggcgcggcgg gccgcgtcga ggccgccggc
     4561 gagctcgccg agggcgcgcc gcgcggcggg cagcagctcg tacccggcgg gcgtcagcgt
     4621 gaccccgccg gggccgcggt cgaacagcgc atgtccgacc ttgcgctcca gccgccggat
     4681 ctgctggctg agcggcggct gggcgatgcc gaggcgttcg gcggcccggc cgaagtgcaa
     4741 ctcctcggcg agcacggcga aggcgtggag ctggtgcagc gcgagctccg gccgttcact
     4801 gccagaccgg tccatacgcg cagggatatc acaccatggc tcagggcgtc ttggacgtat
     4861 catcgctggt cccctaccgt tctggggcat gacagagcga cgcgcgatca tgagtgggtc
     4921 cgtcttcgag gagcggatcg ggtacgccag ggccgtggtg gacggcgacc gggtgcacgt
     4981 gtccggcacc accgggttcg actacgcgac catgaccatc tccggcgacg tggtggagca
     5041 ggcccggcag tgcctgcgca acatcggggc ggccctggcc gaggcgggat gctcgttcgc
     5101 cgacgtggtg cgggtgcgct acctcctgcc ggaccgcgcg gacttcgagc cgtgctggcc
     5161 ggtgctgcgg gagtgcttcg gcgaggtgcg cccggccgcg accatgctca tgtgcgggct
     5221 ggccgacccc cggatgaaga tcgagatcga ggtggacgcc cgcctgccgc ggtgatgccg
     5281 gtctcgtccg ccggcggcgc gaccagtacc ttgagtcggt gatccatcgt ggaaaggtga
     5341 gtcttgaact acgaacgcca gccgtaccgg cgctgtggcc gaagtggcct gctgctgccc
     5401 gccgtctccc tcgggctgtg gcacaacttc ggcggcggca agcccctcga cggacagcgg
     5461 gcgatcatcc gtaaggccct cgacctcggc atcacccact tcgacatcgc cgaccggtac
     5521 ggcccgccgc tgggcgccgc cgagtcggcg ttcggccaga tcttccgcgc cgacctgcgg
     5581 gggctgcgcg acgagatcgt cgtgaccacc aagggcagca accccatgtg ggacggcccg
     5641 tacggcaagg gcaactcgcg caagcacctg ctggccacgc tcgaccggtc gctggagcgg
     5701 ctcggcctcg gcttcgtgga catcttctac ctgcaccgcg acgacccgga gacgccgctg
     5761 gaggagcagg cggccacgct cgaccacatg gtgcgcaccg gccgcgccct gtacgcgggc
     5821 gtgtccaact tctcccccga gcgcaccgcc gggatcgccg cgctgatgcg ttcgctcggc
     5881 acgccgctgc tggtgcacca gccgccgtac tcgctgctca accggggcat cgagcggtcg
     5941 ctccttggcg tgctggagga ggagggcgtc ggctgcgtgg tgtactcacc gctggcgcag
     6001 gggctgctga ccgaccgcta cctcgacggc atcccggagg actcccgggc ggccgagggg
     6061 cggttcctga cggccgacaa ggtcacgccc gaggtgctgg cgttcgtccg ggcgctcggc
     6121 gagctggccg ccgcgcgcgg gcagagcgtg gcgcagctcg cgctggcctg ggcgctgcgc
     6181 gacccgcgcg tcacctccgt gctggtcggc gcctccagcc ccgagcagct ggaggccaac
     6241 gttgcggccg tggaccggct cggcttcacc ggcgacgagc tggccgccgt cgaccgggcg
     6301 gccaaggagt cgggcctcga cgcgtagaga cggcgagccg gccgggacct cgcgggacgg
     6361 agccccgtcc ccgcgcctga gcggcacgga cgccgcccgg gcgcggggaa ggctcggtag
     6421 aaggagccgc tcaggcgcgg tggaaggcgc cccggacgtg caccggcaca cccgtgccga
     6481 gcatcccggg cagcacctcg gccacgttca tcggcatccg cacgcacccg tgggaggccg
     6541 ggtacagcgg caccgacagc gcgccgtgga aggcgatgcc gccgttgaag aagatcgggt
     6601 tgtacagccg gcccaggtac gaggtgtgcc agcccgactt gcgccaggtg gtcttgtagt
     6661 cgcccgtggg cgtgcgggcc gagccgcaga agcgctgctt cttgccctgc cacaccgcgg
     6721 cctcgcagta ggccacgccg ctgcccgagg agatgtgcgt gatcagcttg ggctgcccgc
     6781 ccacgtacag gaccatgacc tgcttggtga ggttgacctc ggcgcgggtc ggccgcccgt
     6841 tggggacgag gaccttcggc gcccgggggc tctccagggc ccgccaggtg cgggcggcga
     6901 ccgtgctggt cggcgcgatg ccgttgacct tctggaaggc ccacacggcc gccagcgtcg
     6961 tcccgccgta ccggccgtcc gcccggcccg gctggtagcc gagctcggcc aggcggcgct
     7021 ggagccacgt gacggcctcg cccttcgcgc cgagccgcag ggtcttgcgc ggcgcctcgg
     7081 ccgtgaccgc cgcggcggtg gtcgtcgggt tggtggtcgt cgggttggtc gtgggggttt
     7141 tcgtgggggt ggtcgtcgcg gcctggagcg ccggcgtccc ggtgggagcg gcggccgcgg
     7201 gccccgtccc gaacccggtc aggacgacca cgccggccgt gacgagagcc gccattcccg
     7261 gcagacgtcg tgccctcacc cgaatcacct cttcagctca acaatcgaat caaaggacct
     7321 tacaccacca ccatgaccag gtaagggcga ggtcaatccc cgtagagtgg ccccatgtcc
     7381 gagaagtcgc ctgacgcaca gcacacggaa ccgtccgcgc cccccaccgc ggccgagctg
     7441 gcggcccgct ccaccgggct gcccgccaac gccgtcatcg tccagggcgc cctgcgcgag
     7501 ctcggcgccg ccggcgagat cgtcgtcctg ccggagaagg ccccgaccgc cgcgaccgcc
     7561 gccgcgcagc tcggctgcga ggtcggcgcg atcgccaaca gcctcgtctt cgacgccgac
     7621 ggcgcgcccc tgctcgtgat gacgagcggc gcccaccgcg tggacgtcga gctggtcgcc
     7681 cgcacggccg gcgtccggtc ggtgcggcgg gccacaccgg agttcgtccg gcaggcgacc
     7741 ggccagccga tcggcggcgt cgcgcccgtg ggccacccct ccccgatccg caccctggtc
     7801 gacacctggc tgagcaagta cgacgtggtg tgggcggcgg gcggccatcc gcacacggtg
     7861 ttcccgacga ccttcgacga gctggtgcgc atcaccgggg gcacaccggt cgacgtcgag
     7921 taatgtgcgc agcgtgatcg agtttcgcgg ggcggggccg gccgagttcg acgagcggct
     7981 ggacacggtg atcgacatct acaccgccgc catgcgcccg cccgcggacc agatcacggg
     8041 gcggcgcagc atcatgcgca accacggcat gtacccgcgg ttccagtgct acttcgccga
     8101 gctgcgcggc gaaccggccg tgcccgtccc cgtcccgtgg ccgggcgcgg ggccgggcgc
     8161 ggggccggtc cggcgggggg cggccaaggt cgtcgggttc gcgtacggtt tccacggcgc
     8221 gccgggccag tggtggcacg acgtggtcta ccgggcgctg gaggagcggt ccgggccccg
     8281 ggtggccgac gcctggctcg gtgacgcgtt cgagctggcc gagatccacg tccatcccga
     8341 ctaccagggc aagggcatcg gccgcgccat gatcaccacg ctgtgcgcgg ggcgcgcgga
     8401 gcgctcggcc gtgctgtcca cccacgaccg gcccacggcc gcccgccacc tctaccgcag
     8461 catgggcttc acggacctgc tctcccggtt cgtcttcccc ggcggctacg aagagtacgc
     8521 gatcgccggc cggccgctgc cgctgaactg aaccggccct gctggcaaag ccttgaccag
     8581 cgggtttggc ggacgtgacg gtcggggatg aatgactacg caaagtaatg gacgctctac
     8641 cccgcgtccg tcccacccct acccgccacc cgccgggtcc ccctgcgggc gggtggcggg
     8701 ccacaccggc cccggcgcgc acaccagtgc cccattgccc cacgggcatc ccgcgggcat
     8761 gaattcttcc ggcgcccggg aatgtccgcg ggcgccggcc ggttctatga cacgtggccg
     8821 gtgtgcccag tgtccccggg cctcacctat cgccttcgcg gaataccgtt cggctggagc
     8881 cgcgttgtgc cactcgccga gaggcgacac gcacaccggt acgcacacgt cgaagcgccc
     8941 gtccccgtca gggggcgggc gcttcgcatg agcgggggcg gcggcctcag accgcgaccg
     9001 gctccggacg cgacaggagc tggaagacct cgcgcgaggc gctcgaccgg ttgaacgtga
     9061 tgaagtggat gcccggcgcg ccctcgtcga gcagccgctg gcacagctcg gcgccgtgct
     9121 cgatgccgag ctgccgcacc gccgccgggt cgtcggcgac ggcctcgaaa cgggccgcca
     9181 gagccggcgg gaacggcgcc cccgacagct gctccgagcg ggcgatcgtg ctcatctggg
     9241 tgaccggcat gatgcacggg atgatcggcg tgtcgcagcc gcgggccgcg acccggtcgc
     9301 gcagccgcag gtagtcgtcg gcctcgaaga acatctgcgt gatcgcgtag tcggcgcccg
     9361 cccggcactt gcgcacgaag aactcggtgt cggagtcgat ggacggcgag cgcggatgct
     9421 tgtaggggaa ggcggccacg cccacgcaga agtcgccggc ctggcggatg agccgcacca
     9481 gctcctcggc gtacaggacg ccctcggggt ggcggaccca ctcgccggtc gggtcgccgg
     9541 gcgggtcgcc gcgcacggcc aggatgttgc gcaccccggc gtcggcgaag cggccgacga
     9601 ggtggcgcag ctcgcgggtc gagtggttga cggcggtgaa gtgggccacc ggcgtgagcg
     9661 tcgtgtcgtg ggcgacccgt tcgacgatgt cgaccgtgcg gtcgcgggtc gagccgcccg
     9721 ccccgtacgt caccgagacg aaggtcggcc gcagcgactc cagctcccgg atcgcgcgcc
     9781 agagctgccg ctcgccctcg tcggtcttcg gcgggaagaa ctcgaaggag aacgaccggc
     9841 cacctgaggc gaggagctcg cggacggtgg ggacgcgatc gggcaggacg gatggtcgac
     9901 caagggccat ggtccaaggt taccgtggcg cggcccgcac cagccgtcac tcgggtggcc
     9961 tggagatccg gcgtcgcccc gcggccacta gtctcaaggc atgaacactg aggccgcgag
    10021 catggacacc ctgcgcgaac aggtggaccg ttgcctgagg gagttcgtcg accggcagct
    10081 tcccctcacg ggcgcgccgg agctggagcc gctccgcctg gccgccaagg agctgctggc
    10141 gggcggcaag cggctgcgtc ccgcgttctg ctactggggg tggcgcggcg cgggcggggc
    10201 cgacctgccg ggcgtctacc aggcggcggc gtcgctggag ctgctccagg cgagcgcgct
    10261 ggtccacgac gacgtgatgg acaagagcga cctgcggcgc ggcatgccct cggcccaccg
    10321 ccggttcgag gcgatgcacg ccgacgccgg ctggcacggc tcggccgagc agttcgggat
    10381 gggcgcggcg atcctgctgg gcaacctgct gctcatctgg tcgggcgaga tgtggcgcgg
    10441 cagcggcctg ccgcccgagt cgctcgcggg ggcgcagccg gtccacgacc acatgcgcac
    10501 cgagctgatg tgcggccagt acctcgacct gctggagcag gcccacggcg agaacacgtt
    10561 cgagtcggcg ctgcgggtcg cgctctacaa gagcggcaag tactccgtgg agcagccgct
    10621 gcggctcggg ctggcgctgg cggcgggcgg gctcacgccg tggatggacg agctgtgcac
    10681 cacgtacggc acgcgggtgg ggatcgcgtt ccagatgcgc gacgacatcc tcggcgtgtt
    10741 cggcgacccg gcggccaccg gcaagccggc cggcgacgac ctgcgcgagg gcaagcggac
    10801 gatgctcgtg gcgcgcacgc tggccgccgc gacgcccgag caggcggcgc tggtgcgcag
    10861 cctgctgggc gacccggggc tcgacgaccg gggcgtggcg gccctgcggg aggtcatcga
    10921 ggacacgggg gcgctgaagg agtgcgagga gctgatcggg gcgtacctga ccgaggcgct
    10981 ggcctgcctc gaccaggcgc cgatcacggc ggaggcgcgc tcggcgctcg ccgagctggc
    11041 ggtcgcggcc acctcacgcc aggcgtgagc cgtcaggcgc cgcccgagga gccgtcaccg
    11101 cccgaggagc cgccgcagtc ggaggagccg gagccgggca tcgtcacacc gtgaaggggg
    11161 atgcccgggt tgccggctcc tctccgcaag gaggggcgtc cggcgatcag cgaccacacc
    11221 gtctagacga cgacaccggc gaacgcgatc accaaaccgg ccgccacgac cgtggacccc
    11281 gtcaccgcgt cgcccccaga cgcttggcga actcggccgc cgcggcgccc gggtcgtcgg
    11341 cctcggtgat cgcccgcacc acgacgacgc gggtcgcccc gtacgccatg acctcgtcga
    11401 ggttgccgag gtcgatgccg ccgatcgcga accacggccg gtcggtgccg agcccggccg
    11461 cgtgccgcag caggggcggc cccggcgccg ggcgccccgg cttggtaggg gtcggccagg
    11521 tcggcccgca gcagaagtag tcgacgccct cctccaccgc cgcggcggac gcctcggcgg
    11581 cggagtgggt ggacctgccg atgaggacgt cgtcgccgag gatctcccgt gcgaccctca
    11641 ccggaaggtc gtcctgcccc aggtggagca cgtccggccg ggcggcgtgg gccacgtccg
    11701 ctcggtcgtt gaccgcgagc agcttgccgt gccggtcgca ggcgtcgcgg aagacctcca
    11761 gcagcgcgag ctcctcgcgc gcctccaggc ccttctcgcg gagctggacg atgtcgacgc
    11821 cgccggccag gaccgcgtcg aggaactcgg ccagatcgcc gcgagcgcgg cggccgtcgg
    11881 tgcagaggta gagccgggcg tcagaaagcg agggcctggg cacgccgctt gacctcagtg
    11941 tggcggcccg cgcggatcgc ctcgatgggc gagcccggca gcgagtcgtc cggggtgaag
    12001 agccagcgca gcgcctcgac gtcgtcgtag ccggcgtcct gcagcacggt gagcgtgccg
    12061 ggcaggccct tcatcacgtc gttgccgtcg aggaacacgg cgggcacgtg cggcccgcca
    12121 ctgccccgcc ggactcccag cagcttgtgg tccttgagga gttgcttggt gcgcccgagc
    12181 gacagctgca tgcgctcggc cacctccgga agagtgagcc actcgttgac gagctgctcg
    12241 gtgtcccggt cgatctgtgc aacagaaagc gtcacgaaac cacaactacc acatggcgcg
    12301 cttgctcaaa caacacaatc ccgtagaggg acatcgggat ctaccaggcg ttccgggtcc
    12361 atccggtggc cggcgtcgat gatgcggcgc ccctggacga ggtcgcgcgg gcggtccacg
    12421 gcgaggaccg cggcgagggt gtcgtcctcg gtcagccagc aggccgacca cttgccctcc
    12481 ggcccgcccc ggtggagcag gcgggagccg gccgggtggt ggcccgcgta ctggaccatg
    12541 tggccgaact gctccgacca gaagtacggc accgggtcgt acaccgcgtc ctcgccgagc
    12601 agcgtggccg cggcgacctc gggcgcgccc agcgcggtgt cccagtgctc gacccgcagg
    12661 cgggtgccgt agcggcgcga ccaccaggcg gcgcagtcgc ccaccgcgac cacgcccggc
    12721 agggaggcgc gcaggtgctc gtcggcgacg acgccgttgt gcaggtcgat gtcggcgccg
    12781 gccagccact cgacggccgg gcggacgccg acgccggtga cgaccacgtg cgcctcgagg
    12841 aactcgccgt ccaccagccg cacgccgccc tcgtccaccg aggcgaccat ggtgccgagc
    12901 cgcaggtcga tcccgtcgta ccaggggagg gtgcgggcgc ccagctcggc gccgacggcg
    12961 tgggacagcg gcgcggggcc ggcctcgacc acggtcacct cgcagccggc gcggcgcgcg
    13021 gccgtggcca cctcggcgcc gatccagccc gctccgatca cgacgacgcg ggcgccgcgg
    13081 acgagcctgg cgcgcagctc cagcgcgtcg tcgagggtgc gcagcacgtg ctgctgcccg
    13141 tcgccgggca gcgtgatcgg gtcggcgccg gtcgcgatga ccaggccgtc gtagggcagg
    13201 tcgccctcgc tcgtctcgac cacgcccgcg cgcaggccgg tggcgctgac gccggggcgg
    13261 aagtccacct ccagcgtcgc gaggtcggag tcgacgaaac tggagtcgct ggtgcccagg
    13321 agcaccgcct tcgacaaggg cgggcggtcg tacgggcggt gccgttcctg tcccagcagg
    13381 acgatctcgc cctcgaaccc gcgggcccgc agggcctcga cactgcgcac tccggccagg
    13441 ccggctccgg ccaccacgac acggttcacg ttcaagacca taacggggcc gccgccgggg
    13501 tttcgcaccg aggccgtagg ctgggggcgt acgacgcgcg ggagtccggc cgtgaccggg
    13561 ctgagaggaa ggcttgaccg ggccttcgac cgcaatccac ctgatccgga tcatgccggc
    13621 gaagggagcg cgcatggagc tgatcgtggg cggcggggtc gtcgggctgt cgatcgcctg
    13681 gcggctgtcg cgggcggggc gtcccgtcac cgtggtcgac ccggccccgg cctccggggc
    13741 ctcgcacgcg gccgcgggca tgctggcgcc cgtgagcgag gtctcctaca ccgaggagcc
    13801 gctgctgcgg ctgggggtgg cgtcgctgcg ccgctggccg tcgttcgccg ccgagctggc
    13861 cgccgacgcg ggactgccgc ccggcgtgct ctcgccctcg aacggcggat ccggcggacc
    13921 ttcgaacggc gggaccggcg cgccctcgaa cggcgggtcc ggggcgcctt cgtacgggct
    13981 ggacttccgc gccgacggca ccctggacgt ggcgttcggc gcggacgacc tcgccgcgct
    14041 ggacgagctg gccgccttca tgaccaagtt gggcctgccg gtggaacggc tgacgggccg
    14101 cgagtgccgg cgcctggagc cgatgctggc cccctcggtg cggggcgggc tgctggcgcc
    14161 gggcgacgcg tgggtggacc cgcgccgcgt cacctccgcc ctgctcgccg ccctggagcg
    14221 gcggggggtc cccgtggtgc gggcccgggt gtcgaggctc ctgcgggcct cacagggccc
    14281 ccaggagggc gcggtcgtgg gcgtggagct ggacgaggcg gccggcggcg gggcggtccc
    14341 cgcggagctc cgggccgacg gggtcgtcct ggcggccggg gtgtggagcg cggagctggc
    14401 cggcgtcccc gtccggccgg tcaaggggca gatcatgcgg ctgcgctcgg ccgagccgct
    14461 gctgagcagg tgcgtgcgcg gcatggtcca cggcaccccc gtctacctgg tgccgcgcgg
    14521 cgacggcgag ctcgtggtgg gcgccacgca ggaggagatg ggcttcgaca cgcgggtgac
    14581 ggccggcggc gtgtacgagc tgctgcgcga cgcccgggag ctggtgcccg gggtgacgga
    14641 gctggaggtg gccgaggtgg tcgccggcct gcgtcccggc accccggaca accttccgct
    14701 catcggcccg agcggcacgc caggcctcac gctggcgacc gggcaccacc gcggcggggt
    14761 gctgctggcg ccgctcacgg cggccctcct ccagggggag gagcccgagc tggcggccct
    14821 gtgctcaccg gcccgccacc gcccggaccc cgcgagtgcc ggccaccgtg atccccgcgg
    14881 cccggccgct cccccgtacg acgagacctc cggttccaag gagatgggat gaaagtgacg
    14941 atcaacggca gcccgcgcga ggtgcccgac ggcaccaccg tggcgcaggc cgtacggatc
    15001 ctgaccaccg ccaccaccgg tgtggcggtg gccgtgaacg acgaggtcgt gacgcgcggc
    15061 tcgtgggaca ccacggcgct cggcgacagc gaccgcgtcg aggtgctgac ggcggtgcag
    15121 ggtggatgat ctgatcatcg ccggggagaa gttctcgtcc cggctcatca tgggaaccgg
    15181 cggggcgccc tcgctggagg tgctggacca ggcgctcgcc gcctccggca ccgagctgac
    15241 cacggtggcg atgcggcggc tcgacccgtc ggcgcgcggc tccgtcctgg acgtgctgcg
    15301 ccggcgcggc atcaaggtgc tgcccaacac cgcgggctgc ttcacggccg gcgaggccgt
    15361 gctgacggcc cggctggccc gcgaggcgct cggcacgaac tgggtcaagc tcgaagtgat
    15421 cgccgacgag cggaccctgc tgcccgaccc gatcgagacg ttcgacgcgg ccgagcggct
    15481 ggtggccgac ggcttcgtgg tgctgccgta catcggcgac gaccccgcgc tggcgcgccg
    15541 cctggagcag gcggggtgcg cggcggtcat gccgctcggc gcgcccatcg gctcggggct
    15601 cggcatccgc aacccgcaca acatcgagct catcgtggag gcggccggcg tgccagtgat
    15661 cctcgacgcg ggcatcggca cggccagcga cgccgcgctg gcgatggagc tgggctgcga
    15721 cgcggtgctg ctggcgacgg ccgtcacccg ggcgcagcgg cccgacctga tggcggcggc
    15781 catgcggagc gccgtccagg ccggacgcct cgcccgccag gccggccgca tcccgcgccg
    15841 ccgctacgcc gaggcgtcct ccccgatgac gccgtaggcg tggctcgggc gcgcgcccga
    15901 gccttgccta gcggggcgta tcggatgtcc gcaaaggggc ggccgtcaag ccccaagggc
    15961 cggcacggcg ggcggcgggc tcccgggcga gggctccgag gcgggcggtc ccggccccgc
    16021 ccgccggggc ggcgagggcg ccggagatcg gacggcgccc tggtcccgcc gggatcgggg
    16081 cggccggagg gggccggacg agggccacgg gtccgcatcg tttcggatgg tcgcgccctg
    16141 cgggccgcga aacgcccgta aactcggcga cgtggacacg acgactgcgg accccctggt
    16201 cgggcggacc ctggacgggc gctaccgcat cgagtcccgg atcgcgcggg gcggcatggc
    16261 gaccgtctac ctcgcgctgg acgtccggct cgaccgcacg gtcgcgctga aggtcatgca
    16321 ccgctcgctc gccgaggacc cggcgttcgt gcggcgcttc atcggcgagg ccaagtccgt
    16381 ggccagcctc tcccacccca acgtggtcca cgtcttcgac cagggcaccg acggcgacgt
    16441 cgtctacctg tccatggagt acgtccccgg caggacgctg cgcgacatcc tcaacgagcg
    16501 cggcaggctg ccggcccgcg aggcgctgga gatcctcatc ccggtgctcg cggcgctggg
    16561 cgcggcccac caggccggca tggtgcaccg cgacgtcaag ccggagaacg tgctgatgac
    16621 ggccgacggc cgggtcaagg tcgtggactt cggcctggcg cgggccatcg aggcgaccaa
    16681 ccagacccgc accggcatga tgatcggcac gatcggctac atgtcgcccg agcaggtgac
    16741 caccggccgg gccgacgtgc gcaccgacgt ctacgcggcc gggatcatgc tgttcgagct
    16801 gctgacgggc cagccgccgt acgagggcga gacgcccatg tccgtggcct accgtcacgt
    16861 ccacgacacc gtgccggcgc cgtcgtcgct gaaccccgag gtgccgcccg tggtcgacgc
    16921 gctggtggcg cacgccacgg cgcgcgagcc ggacgcgcgg cccgccgacg cgaccgcgat
    16981 gctggtcgag gcggtcgagg tgcaccgcca gctcccccgg ctcaccgctc cgggcgtccc
    17041 gcacacgggc gcccggtact cgctgcccgg caccggcccg cacgcccctt cggggccgca
    17101 cgccccctcg ggctcgcttc cggtgcccac ggcgcagctt ccctccggcg tccacacctc
    17161 gcccgccggg ggccacctgc cgggcccccg gacgggcccc cattcggggg cgcagcccac
    17221 cggaccggct cacggcggtt acggcccgca gcccgcctcc cagccgggca attacggccc
    17281 gcagcccgct tcccagccgg ttggtgcggg ctcgccgggg atgacggtgg ccatgccgca
    17341 ggtcccgccc ggcggcgcgg cgctccccaa cccgacgatg atccagccgc gcgccgagac
    17401 gccggcggag ccgccctccg ggcggcggcg cgggttccgg ccgagctgga tcatcgtggc
    17461 gctcgccgtc gtgatggtgg ccgcgatcgg cctgaccggc tggtacgtct cccgccccca
    17521 gtacgtgacc gtgcccgccg acctggtcgg caggccggtg tccctggtcg aggcgaagct
    17581 cgcctccggg ggcctgaagg tgaaggtcgc gcagggccgc cacgacgaca agaccgacga
    17641 ggggatggtc ctcagcctcg acccggtggg cggtcaggag gtggaggcgg gcacgaccgt
    17701 gacgctcgtg ccctcgctcg gccccaagct cgtggtggtg cccaaggtgg cgggcatgtc
    17761 ggccgacgac gcccgcgccg ccatcgccaa ggccggcctg accgtgggca ccgtccggcg
    17821 gctggccaac cccgacgtgg cccgcgacac ggtgatccgc acctcgccgc tcgtgggcga
    17881 gaagctcaag gagggcacca aggtctccat ctacgtgagc gccgggctca ccatgcccga
    17941 cgtcgcgaag atgcccaagg accaggccgc cgccttcctg caggagcagg gcttccaggt
    18001 gcaggtcaac gaggtggacg acgacgccga gccgtgcacg gtcatcgccc agtcgcccaa
    18061 ggccggcgcg gaggtcgacc ggggcgccgc ggcgatggtc acggtggcgc gctgccagag
    18121 cgacttctgg gactggtgga agggcgacaa cgaggcccgc gaagaccagg agcaccagct
    18181 cgtgcccgcg gtcatgggca agaacgtcaa cgacgcccgc caggagctcc agcagctcgg
    18241 ctggaaggtg cgagtcctca agctgggcaa gggcagcggg gtcgtccgct tccagcggcc
    18301 cctgcccaac agcgagcgcc cgccgggctc ggaggtcatc ctctggcact gacccccgcg
    18361 cgggtcagcc cgtgaggtgg ccgtgcagcc gcacgcgggc cagccctccg tcggggtgga
    18421 tgtcgacccg tacgtgcgtg acggggtcga cgtgggcgag gcggaagcgg tgcggggtgt
    18481 cgggctgcag ccgcgtccgg ggcagcagct cgacctcgcg gtcgccgtcg aggccggtga
    18541 gggtcacggc ggcgggggcg ttgtggatga ggttcgtggt gtcgatctcg gcgagccgga
    18601 cgacgccccg cccggccagc cggatgacca gccactcgtt gccctcctcg cggcggcggg
    18661 cggtctccca tccctccgcc tggtggcggg ccagtccggg ggcgatgacg ttgaggggcg
    18721 aggagtagta ggcgttggag caggcggtga ccaggccgcc gttgtgcagc gcggccaggt
    18781 cgaggctcag cccgtcgtac accgacaggt cggggcgcgc ctcgccgtgg acccgcagcc
    18841 gggcgatgcc gccgtcgggg tacatgttca gccgtacgtg cgtgtaacgg acgtcgccgg
    18901 cgacctccac ggggtgctcg gcgtcgccgc gcagggcgac cttgggcacg atctcggtcc
    18961 agcgggcgtc gagcagctcg gcgggcgacg ggtggccgtc gacggccgcc gcctcgaccg
    19021 acgcgtgggt ggggtggttg ccggtgaacc aggccgtgtc gatgaccacg ccgcgcacgg
    19081 cgccgggcag gccgagccgg acgatcgccc agtcgtgccc cggcccgcgc cgccgccgcg
    19141 tctcccagcc gtcgtacacc tggcccttgt cgccgaacgt ctggggccgg aacgcgggcc
    19201 ggccgggcct gatgaggctc tccttctcgg cgaaggactc gtcgctggcg gcgacgaccg
    19261 agccgcccag tgtgcgcagc gccaggtcgg gcagcgtggt gaagccggcg gacggccgtt
    19321 cgggcgccat ctacttgtct cccagcagga agaccccgtg cggctcgccg tcggcgggcc
    19381 ggccgcggag ccaggtggtg agcaccgcgc ccctcagggt gcggccgtgg tacggggtga
    19441 cggggttgcg gtggtggagg gcgcgggcgt ccaccgggtt ggcggcgtcc gggtcgaagg
    19501 ccaccaggtc ggcgtcgttc ccgggctcga cggcgccctt gcgcgggatg ccggcgatcg
    19561 cggcggggcg ggcggacatc cagcgggcca cgtccgtcag cccgtacccc ctgcgtgacg
    19621 cctccgtcca cacggcgggc agcccgagct ggagcgaggc gacgccgccc caggcggcgg
    19681 cgaagtcggg caccttgagg tcggcggtgg acggcgagtg gtcggagacg acgcagtcga
    19741 ggacgccgcg cgccaggccc tcccagaggc ggtcgcggtt ggccccgtcg cggatcggcg
    19801 ggcagcactt gtagctcgtg tcgccctccg gcacctgctc ggccgccagc gtgaggtagt
    19861 gggggcacgt ctcggcggtg accggcacgc ccctggcgcg ggcctcctcc agcggtccga
    19921 ggcaggcggc gctggagacg tgcaggacgt gcaccctggc gccggtctcc tcggccagcc
    19981 ggatcaccag ctcgacggcg ctgcgctcgg ccgcgccggg ccgcgactcc aggaactccc
    20041 ggtacgtggg cccggccggt tcggccagca gcgccgggtc ctcggcgtgc accaccagga
    20101 gcccgccgaa cccggcgatc tccgtcatcg cccggcgcgc ctcgtccggg cgcagcggcg
    20161 ggaactcctc caccccggag ggcgacagga agcacttgaa gccgcgcacg ccgcgctcgt
    20221 gcagcggccg caggtgctcc acgttgccgg gcacggcgcc gccccagaac gcggtgtcca
    20281 cgtggcagcg gccctcggcg gcgcgcagct tggcgtccag ggcgtcgggg gtgacggtgg
    20341 gcgggacgga gttgagcggc atgtccacga tcgtggtgac gcccccggcc gccgccgcgc
    20401 gggtcgccga cgcgaacccc tcccagtggg cgcggccggg ctcgttgacg tggacgtggg
    20461 tgtcgaccag gcccggcagg aggggcaggg cgcgcaggtc gacgtcctcg gcggtctcca
    20521 ggggcgcctc gtaggggtgc agggccgcga tccgcccgtc gcgcacggcc acggcggcgg
    20581 gccgctcgcc ctcgggcgtc accacccgcc gcgaccgcac caccaggtcg aacatggccg
    20641 ctcccttcct cagcacgggc cggcgcccgt ccttacgtcg tgtctcagag gcggtcggcg
    20701 gccaggcggg ccgccagtcg ctccaggagg gcgccggcgt cggccatgca gcgctccggg
    20761 tcgggctcca ggtcggtcag cgcgtacgcg gcctcgatgc ccgccgcccg cagctcgtcg
    20821 tcggagagcg cgcgccgccc gcacaccgcg accacgggga cacccgcctt ggccgccgcc
    20881 tgggcgaccc cgatcggggc cttgccccgc agtgactggc cgtccagcga cccctccccc
    20941 gtgatcacca gccgcgcgcc gcgcacctgc tcgccgaagc cgagcaggtc gagcaggtag
    21001 tcgatccccg ggcggatctc cgcgcccagg aaggcgaggg cggcgaagcc cacgccgccc
    21061 gccgcgcc
//
