LOCUS       NZ_CP047883            20876 bp    DNA     circular CON 27-JUL-2024
DEFINITION  Streptococcus mitis strain S022-V3-A4 chromosome, complete genome.
ACCESSION   NZ_CP047883
VERSION     NZ_CP047883.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus mitis
  ORGANISM  Streptococcus mitis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2086958)
  AUTHORS   Pinzauti,D., Iannelli,F., Pozzi,G. and Santoro,F.
  TITLE     Complete genome sequence of the tetracycline resistane Streptococcus
            mitis isolate S022-V3-A4
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2086958)
  AUTHORS   Pinzauti,D., Iannelli,F. and Santoro,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JAN-2020) Department of Medical Biotechnologies,
            University of Siena, Viale Bracci, 16, V lotto, I piano, Siena, SI
            53100, Italy
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 28-NOV-2018
            Assembly Method                   :: Unicycler v. NOV-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400.0x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013305725.1-RS_2024_07_27
            Annotation Date                   :: 07/27/2024 01:18:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,027
            CDSs (total)                      :: 1,952
            Genes (coding)                    :: 1,893
            CDSs (with protein)               :: 1,893
            Genes (RNA)                       :: 75
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 24 of 59
            Pseudo Genes (incomplete)         :: 39 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 16 of 59
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:35:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 824467
            Orig. end                         :: 845343
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047883.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Francesco Santoro.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20876
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20876
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20876
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10876](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10876
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(91..108)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: medium, score: 27.8"
                     /tool="antismash"
     misc_feature    132..146
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.04"
                     /tool="antismash"
     gene            754..1551
                     /locus_tag="M594_RS04080"
                     /old_locus_tag="M594_04105"
     CDS             754..1551
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /locus_tag="M594_RS04080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04105"
                     /product="formate/nitrite transporter family protein"
                     /protein_id="WP_173876041.1"
                     /transl_table=11
                     /translation="MSSSEFISKIDYYCHKKESLFKQSKLKYAIRSMFAGAFLTFSTAA
                     GAIGADLLNSIVPSSGYFLFPFVFAWGLVYIVFLNAELVTSNMMYLTAGAFLKKIDWKK
                     AMIILLYCTLFNLIGALVAGWAFANSSAFSHLTHDSFLPKLVAKKLARPSDLVLLEGIL
                     ANVFVNIAILSSILVKDGAAKLWIILSAISMFVFLSNEHIAANFASFSIMKFSMIADQV
                     PHFDLPNILRHWGVTFIANFIGGGLLIGLPYAFLNKNEDTYVD"
     misc_feature    complement(1693..1706)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.54"
                     /tool="antismash"
     misc_feature    1806..1821
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.55"
                     /tool="antismash"
     gene            1845..2642
                     /locus_tag="M594_RS04085"
                     /old_locus_tag="M594_04110"
     CDS             1845..2642
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /locus_tag="M594_RS04085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04110"
                     /product="formate/nitrite transporter family protein"
                     /protein_id="WP_000254773.1"
                     /transl_table=11
                     /translation="MVSSEFISKIEFACKKKESLYSQSKFKYAIRSMFAGAFLTFSTAA
                     GAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISWRK
                     TAEILLYCTLFNLIGALIAGWGFAHSAAYAHLTHDSFISGVVEMKLGRSNELILLEAIL
                     ANIFVNIAILSFVLVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVAADSI
                     ANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            2790..4070
                     /locus_tag="M594_RS04090"
                     /old_locus_tag="M594_04115"
     CDS             2790..4070
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (58-224). E-value:
                     4.8e-12. Score: 37.6. Matches aSDomain:
                     nrpspksdomains_M594_RS04090_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /locus_tag="M594_RS04090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04115"
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /protein_id="WP_173876042.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.6e-10, bitscore:
                     37.6, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.7e-15,
                     bitscore: 54.0, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 1.1e-09, bitscore:
                     34.6, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRDFKFETLQLHAGQVVDPATKSRAVPIYQTTSFVFDDTQEGAD
                     LFALRKPGNIYTRITNPTTAAFEERIAALEGGVGSLATASGMAAVTYTILALAHAGDHV
                     VAASTIYGGTFNLLKETLPRYGITTTFVDVDNLDEVEAAINDNTKLVLIETLGNPLINI
                     PDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSATKFIGGHGTTIGGVIV
                     DSGRFDWAASGKFPQFVEEDPSYHNLSYTRDVGAAAFIIAVRVQLLRDTGAALSPFNAF
                     LLLQGLETLSLRVERHVQNAEKIVDFLVNHPKVEKVNYPKLADSPYHALAEKYLPKGVG
                     SIFTFHVKGGEAEARKVIDHLEIFSDLANVADAKSLVVHPATTTHGQLSEKDLEAAGVT
                     PNQIRLSIGLENVDDLIEDLRLALEKI"
     aSDomain        2964..3461
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M594_RS04090_Aminotran_1_2.1"
                     /evalue="4.80E-12"
                     /label="M594_RS04090_Aminotran_1_2.1"
                     /locus_tag="M594_RS04090"
                     /protein_end="224"
                     /protein_start="58"
                     /score="37.6"
                     /tool="antismash"
                     /translation="ITNPTTAAFEERIAALEGGVGSLATASGMAAVTYTILALAHAGDH
                     VVAASTIYGGTFNLLKETLPRYGITTTFVDVDNLDEVEAAINDNTKLVLIETLGNPLIN
                     IPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSATKFIGGHGTTIGGVI
                     VDS"
     gene            4166..5440
                     /locus_tag="M594_RS04095"
                     /old_locus_tag="M594_04120"
     CDS             4166..5440
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /locus_tag="M594_RS04095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04120"
                     /product="DUF2130 domain-containing protein"
                     /protein_id="WP_173876043.1"
                     /transl_table=11
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKEVHDRMKQELA
                     LAEQKAMNEQQSKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSNQALLAKDKEVQA
                     LENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASLKQNYEAQLKAA
                     SEQVEFYKNFKAQQSTKAIGESLEHYAESEFNKVRSFAFPNAYFEKDNKVSARGSKGDF
                     IFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLVTMLEA
                     DNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALIREQNIDIT
                     HFEEDLDAFKLAFAKNYNSASINFGKAIDEIDKAIKRMEEVKKFLTTSENQLRLANNKL
                     EDVSVKKLTRKNPTMKAKFEALKGE"
     gene            5630..5830
                     /locus_tag="M594_RS04100"
                     /old_locus_tag="M594_04125"
     CDS             5630..5830
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M594_RS04100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M594_04125"
                     /product="hypothetical protein"
                     /protein_id="WP_173876044.1"
                     /transl_table=11
                     /translation="MSKVYHGEQVLKAVVATVFVIGTLIDGVTVSASTFVFGVLIAILV
                     IASDFLYLSSTMEDNGERDIK"
     gene            5808..6644
                     /locus_tag="M594_RS04105"
                     /old_locus_tag="M594_04130"
     CDS             5808..6644
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237862.1"
                     /locus_tag="M594_RS04105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04130"
                     /product="hypothetical protein"
                     /protein_id="WP_173876045.1"
                     /transl_table=11
                     /translation="MVKEILNNYSLKISRIEISKLYNLTKIVYICLIPIVCLSFIGMVV
                     ELFKGGEMNFMKFITYTVVCFGFEALLSLNNKLVKLAVDNIFLTDINFEKHINYYRYVA
                     EHSVKSQQLFNNSNYLLAIAQSSYYQGKFEETLDNLGRINFEDKNFNKKFEIELSTTYF
                     KILSLIHADKTEEISHQIDMLATLKVRTNSQVVRKTNVINIIKAIEDLVLNKKSNDYFD
                     ITEPESKLARIMFSYYGALNAQLKGDEARARSLFESIAHENPELFYVQEARKYLEK"
     gene            6719..7597
                     /gene="truB"
                     /locus_tag="M594_RS04110"
                     /old_locus_tag="M594_04135"
     CDS             6719..7597
                     /EC_number="5.4.99.25"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /GO_process="GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="truB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /locus_tag="M594_RS04110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04135"
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="WP_173876046.1"
                     /transl_table=11
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGVL
                     PIAVGKATRMVEFMQDEGKVYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDEAI
                     ASLTGSITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYEGHIA
                     RFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAGKVEA
                     DQLNFLHPLEIGTGDLVKVFLTQEEAIEVRFGRFIELEQTEQELAAFEGDTLLAILEKR
                     DNLYKPRKVFS"
     gene            7708..8346
                     /gene="udk"
                     /locus_tag="M594_RS04115"
                     /old_locus_tag="M594_04140"
     CDS             7708..8346
                     /EC_number="2.7.1.48"
                     /GO_function="GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="udk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /locus_tag="M594_RS04115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04140"
                     /product="uridine kinase"
                     /protein_id="WP_001181376.1"
                     /transl_table=11
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKD
                     QSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQEP
                     QDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVIDQYLG
                     VVKPMYHQFIEPTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            8474..9814
                     /gene="xseA"
                     /locus_tag="M594_RS04120"
                     /old_locus_tag="M594_04145"
     CDS             8474..9814
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /locus_tag="M594_RS04120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04145"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_173876047.1"
                     /transl_table=11
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQYF
                     SLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDGIG
                     TLAIQFEQLKKKLTEEGLFQERFKQPLPQFSKRIGVVTSRSGAVIRDIITTVSRRFPGV
                     DILLYPTKVQGDGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVVRAIF
                     ESRLPIISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDLLAHLQNQEKRMATA
                     VRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDNKQTVQA
                     RTHRLVQLSPVTKIQRYQDRLGQLDKLLRSQMALVYDAKVAEVKRLSEALLMLDTSRIV
                     ARGYAIVKKEESVVDSVENLKKKDQVTLLMRDGRVELEVKDVKTKEI"
     misc_feature    complement(8514..8528)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.47"
                     /tool="antismash"
     gene            9792..10004
                     /locus_tag="M594_RS04125"
                     /old_locus_tag="M594_04150"
     CDS             9792..10004
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /locus_tag="M594_RS04125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04150"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_000043226.1"
                     /transl_table=11
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAIAAFQKGMVLSKEL
                     QATLDKAEKTLVKVMQEDGTESDFE"
     gene            10001..10876
                     /locus_tag="M594_RS04130"
                     /old_locus_tag="M594_04155"
     CDS             10001..10876
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /locus_tag="M594_RS04130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04155"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_173876048.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.7e-55, bitscore:
                     183.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQEKLAHVESALEDFYGDQQFSSSLRESVLYSIHAGGKRIRPF
                     LLLEVLEALHIAIKPAHAQVAAALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFGEA
                     MAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSMGMVAGQVLDMEGEHQHLS
                     LEELQTIHANKTGKLLAYPFQAAAIIAELAPEMQVKLKTVGELIGLAFQVRDDVLDVTA
                     SFEEIGKTPQKDLQAEKSTYPALLGLEEAIAFCNQTLDQANAKLEEIAQQVPFDIGSIV
                     SVVESLRING"
     gene            10869..11684
                     /locus_tag="M594_RS04135"
                     /old_locus_tag="M594_04160"
     CDS             10869..11684
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /locus_tag="M594_RS04135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04160"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_173876049.1"
                     /transl_table=11
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPGE
                     KIPDDTELKLKGEKLKYVSRGGLKLEKALQVFELSVEGATTIDIGASTGGFTDVMLQNG
                     AELVFAVDVGTNQLAWKLRQDPRVISMEQFNFRYAEKTDFEQEPSFASIDVSFISLSLI
                     LPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDSKVHQNVLESVTTMAVEEGFSV
                     LGLDFSPIQGGHGNIEFLAYLKKEESANNCVLAEIEEVVERAHSQFKNE"
     gene            11677..12108
                     /locus_tag="M594_RS04140"
                     /old_locus_tag="M594_04165"
     CDS             11677..12108
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /locus_tag="M594_RS04140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04165"
                     /product="arginine repressor"
                     /protein_id="WP_173876050.1"
                     /transl_table=11
                     /translation="MNKKERLEKIRRFVTDYQIGTQEEIVEHLKEAGITATQATVSRDI
                     KELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVKAQ
                     LTENFSDKIFSCLADDSSILVIARSESLAEKIFEQVKNW"
     gene            12115..13782
                     /gene="recN"
                     /locus_tag="M594_RS04145"
                     /old_locus_tag="M594_04170"
     CDS             12115..13782
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /locus_tag="M594_RS04145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04170"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_173876051.1"
                     /transl_table=11
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNMM
                     LGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLEMGDEIIIRREILQNGRSI
                     SRVNGQMVNLSVLRAIGQHLVDIHGQHDQEELMRPQLHIQMLDEFGDTAFWALKETYQT
                     SFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLSLNQEREKLLNH
                     KNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYYVLEDI
                     SKRLEAIIEDLDFDGNRLMQIENRLDLLHTITRKYGGTVDDVLLYFAKITEEYNLLTGN
                     NLSSEDMEAELKKLEVNLVDLAGQLASARHDLAQQLEAEIKQELQDLYMEKAQFQVRFS
                     KGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKEGKTSIVFD
                     EVDTGVSGRVAQALAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKISNEHSTVSTV
                     RLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            13784..14512
                     /locus_tag="M594_RS04150"
                     /old_locus_tag="M594_04175"
     CDS             13784..14512
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /locus_tag="M594_RS04150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04175"
                     /product="metallophosphoesterase family protein"
                     /protein_id="WP_173876052.1"
                     /transl_table=11
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSRR
                     VLEMVKDLVDNQGAICLSGNHEYMFLTWLDNPEESYDHYRRNGGDTTINSILGRPLDAP
                     VDGVEDAKRVTTEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKVWLR
                     KPFHEAENHTGKTIVFGHTPVYGLLNQDRGTAELWTTEDGKIGMDGGAVYGGVLHGIVF
                     TDQGMTEHHFIENDGFVAED"
     gene            14591..16414
                     /gene="lepA"
                     /locus_tag="M594_RS04155"
                     /old_locus_tag="M594_04180"
     CDS             14591..16414
                     /EC_number="3.6.5.n1"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="lepA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /locus_tag="M594_RS04155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04180"
                     /product="translation elongation factor 4"
                     /protein_id="WP_001047207.1"
                     /transl_table=11
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREM
                     QAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAAC
                     EGAILVVDAAQGIEAQTLANVYLALDNDLEIMPVINKIDLPAADPERVRTEIEDVIGLD
                     ASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQVRVM
                     DGVVKPGDKIQLMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVQDTRVGD
                     TVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETS
                     QALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMDVSNPSEF
                     PDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLA
                     EIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFIVHKDFAYER
                     GKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGGDVSRKRKLLE
                     KQKAGKKRMKAIGSVEVPQEAFLSVLSMDEE"
     gene            16553..17401
                     /gene="dprA"
                     /locus_tag="M594_RS04160"
                     /old_locus_tag="M594_04185"
     CDS             16553..17401
                     /GO_process="GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dprA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /locus_tag="M594_RS04160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04185"
                     /product="DNA-processing protein DprA"
                     /protein_id="WP_173876053.1"
                     /transl_table=11
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISG
                     CRNPAVFMERYFQIDDAHLEKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLDLL
                     KFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMVALQNGGKTIA
                     VIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEKPLKFHFPARNRIIAGLCRGVIVA
                     EAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLATSGQDVLAEFE
                     F"
     gene            17625..19712
                     /gene="topA"
                     /locus_tag="M594_RS04165"
                     /old_locus_tag="M594_04190"
     CDS             17625..19712
                     /EC_number="5.6.2.1"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="topA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /locus_tag="M594_RS04165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04190"
                     /product="type I DNA topoisomerase"
                     /protein_id="WP_173876054.1"
                     /transl_table=11
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGHI
                     RDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAISWH
                     LAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRVLDRLVGYSISP
                     ILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTIDGVFKKGTKQFQASFYGV
                     DGKKLKLTSNDEVKEVLSRLTNKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFR
                     TRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGSKYSKHG
                     SKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQMTAAVFDT
                     MAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNSKPEQHFTQ
                     PPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLVAKRFEPTELGEIVNKLIV
                     EYFPDIVNVTFTAEMEGKLDDVEVGKEQWQRVIDAFYKPFSKEVAKAEEEMEKIQIKDE
                     PAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPSCHQGQIIERKT
                     KRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQVVCSKGDYEEEKI
                     K"
     gene            19969..20328
                     /locus_tag="M594_RS04170"
                     /old_locus_tag="M594_04195"
     CDS             19969..20328
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /locus_tag="M594_RS04170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M594_04195"
                     /product="YbaN family protein"
                     /protein_id="WP_050083961.1"
                     /transl_table=11
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKRF
                     EDWLYHTKLYQTYVADFRETKSIARERKKKIIVSIYILMGISIYFAPLLPVKIGLGALT
                     IFITYYLFKVIPDKE"
     misc_feature    20774..20788
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.11"
                     /tool="antismash"
ORIGIN
        1 aggtatcaaa agaaaaattg gaagaaaatc aagatacaga aggaaatttt gactttgact
       61 ctgtaaaagc tatctcgtca gaagctgtct tatcctcaca atgggattcg caaaaattgc
      121 cagttatcgg tggaattgct gttcctgagg tagaaattaa cttgcctatt tttaaggggc
      181 ttgataatgt caatctcttc tatggagctg gtacaatgaa gcgtgaccaa gtgatgggga
      241 aaggaaacta ttcacttgcg agccatcaca tcttcacggc ggaaaatgcc agccaaatgc
      301 tcttttctcc attatcacgc gctaaaaatg ggatgaaaat ttacctaacc gataaggata
      361 aagtttatac ctatgaaatc cgtgaagtga agcatgtgac tccagatcgc gttgatgaga
      421 ttgatgaccg tactggagtt gatgaaatca cacttgtaac ctgtgttgac tatgatgcga
      481 cagaacgtat tatcgtaaaa ggtgacttga aagatacaaa ggattattca caaacacctg
      541 aagaaattct aacagctttc aatcaaccat ataaacagcg ctattaatag ttaaagaatc
      601 agtaaacatt ttattttact ggttcttttt atattgcttt ataagcatgc taagtaatga
      661 taaatcaata caaatactag catttttcaa aaacaattac ctattttaat attttgtgtt
      721 ataatactaa atataaaaaa ataggagacg tttatgagtt cgtcagagtt tatttcgaag
      781 attgattatt attgccacaa gaaagaaagt cttttcaagc aaagtaagtt aaagtatgca
      841 attcgttcta tgtttgcagg tgctttttta acctttagta cagctgccgg cgctattggt
      901 gcagatttac ttaatagtat tgttccaagt agtgggtatt tcctgttccc atttgttttt
      961 gcttgggggc tggtttatat tgtctttcta aatgcggaat tggtaacttc caatatgatg
     1021 tatttaacag caggcgcatt tttgaaaaag attgattgga aaaaggcaat gattatttta
     1081 ctctattgta ctttgtttaa tctcattggt gccttggtgg ctggatgggc ctttgccaac
     1141 tcgtcagcct tttcgcattt gacccatgat agtttccttc ctaagcttgt agccaagaaa
     1201 ttggcgcgtc caagtgattt agtcctgctt gagggaattc ttgccaatgt atttgtaaat
     1261 attgccattc tttcatctat attagtcaaa gacggtgctg ccaaactatg gatcatttta
     1321 tcagctattt ccatgtttgt cttcttgtcc aatgagcaca tcgctgccaa ttttgcttcc
     1381 tttagtatta tgaaattcag catgattgct gatcaagtac ctcactttga tcttccaaat
     1441 atccttcgac attggggtgt aacctttatt gctaacttta taggtggagg tcttctgatt
     1501 ggtttaccgt atgcctttct aaataagaat gaagatacat atgttgatta agaagagtta
     1561 gtgtatcagg gagagtcaga acgattctct cttttttctt ttacaaaata ggcttgcaga
     1621 gaaaatcgtt ttgtaaattg taacaacaaa atatattaaa tagaataaaa gttattccat
     1681 gcaatcttta tattctaata attaaaaatt ctaaaagctt gttattcaaa caatgtaaac
     1741 gattactgga tttataaatt tattaaaaat acaattagga aaggcttttc attatatcga
     1801 ttttatgtta taattatcac aaataaaagt tttaggagtt tattatggtt tcttcagaat
     1861 ttatctcaaa gattgaattt gcttgcaaga agaaggaaag tctttatagt caaagcaaat
     1921 ttaagtatgc gattcgttct atgtttgcag gtgcattttt aaccttcagt actgctgctg
     1981 gtgcggttgg ggctgacttg attaataaaa ttgcaccagg tagtggacgc ttcctcttcc
     2041 catttgtctt tgcttggggc ttggcctata ttgttttctt gaatgccgag ttggtaacat
     2101 caaacatgat gttcttgact gctggtagtt tcttgaaaaa aatttcttgg agaaagacag
     2161 ctgagatttt actttactgt accttgttca accttatcgg ggctttgata gcaggttggg
     2221 gctttgctca ttcggcagcc tatgcacatc tgacacacga tagtttcatc tcaggggttg
     2281 ttgagatgaa gttaggccgt tcaaatgaat taatcttgct tgaggcgatt ttggcaaata
     2341 ttttcgtaaa tattgcgatt ctttcatttg ttttggtcaa agatggtggt gccaaacttt
     2401 ggctagtttt atcagcaatt tacatgtttg tattcttaac aaacgagcac attgcggcga
     2461 attttgcttc tttcgctatt gtgaaattca gtgttgctgc tgattcaatt gctaacttcg
     2521 gtgttggaaa tatgcttcgt cactggggtg taaccttcat tgggaacttc attggtggtg
     2581 gtctcttgat gggtcttcca tatgccttcc tcaataaaaa tgaagatact tatgtagatt
     2641 aagaaaatga gcacgattga gtcgtgcttt tttcattttt aaaataaggt aatagctatt
     2701 tcttatatca aaatatagaa aactgatatt tgtaaactat accttaaggt gctacaatat
     2761 ccttaatcaa actatttgga ggtcgcccta tgactcgtga ttttaaattt gaaactttgc
     2821 aactacatgc tggtcaagtt gtggatccag ctaccaagtc tcgtgcagtg ccgatttatc
     2881 aaacaacatc ttttgttttt gatgacacgc aggaaggtgc cgatctgttt gccttgagga
     2941 aaccagggaa catttatact cgtatcacca atcctacaac ggctgctttt gaagaaagaa
     3001 ttgcagctct cgaaggtggt gtcggatctc ttgcaacagc atcaggtatg gctgcagtga
     3061 cttatacgat tttggctctt gctcatgcag gtgaccatgt agtggcagca tcaactattt
     3121 acggtgggac tttcaatctc ttgaaagaaa cccttcctcg ttatggtatc acaacaacct
     3181 ttgtcgatgt ggataatttg gatgaagtag aagcagctat caatgacaat accaagcttg
     3241 tcttgattga aaccttgggc aaccccttga ttaacattcc agatttggaa aaattggcag
     3301 agattgctca taagcatcag attccacttg tttccgacaa tacctttgct acaccttact
     3361 tgattaatgt cttttctcac ggcgtagata ttgctattca ctcagcgact aagtttatcg
     3421 gtgggcatgg tacgactatt ggaggcgtga ttgtcgatag cggtcgtttt gactgggcgg
     3481 cttcaggaaa attccctcaa tttgttgagg aagacccaag ctaccacaat ttgagctata
     3541 ctcgtgatgt gggtgcagca gcctttatta tcgctgtccg tgtccaattg cttcgtgata
     3601 caggtgcagc cttgtcacca ttcaatgctt tcctcttgct tcaaggactt gaaacccttt
     3661 ctcttcgtgt cgaacgtcat gtgcaaaatg cagagaaaat tgttgatttc cttgtcaacc
     3721 atcctaaggt agaaaaagtc aactatccaa aacttgctga tagtccttac catgccttgg
     3781 ctgagaaata cttgccaaaa ggtgtgggct caatctttac cttccatgtc aaaggtgggg
     3841 aagcagaagc acgcaaggta attgatcatt tagaaatctt ctctgacctt gccaatgtgg
     3901 cagatgctaa atcgcttgtt gttcatccag ctacaaccac tcacggtcaa ttgtcagaaa
     3961 aagacctaga agcagcaggt gtcacaccaa accaaattcg tttgtcaatc ggtcttgaaa
     4021 atgtagatga tttgatcgaa gacttgcgct tggccttgga aaaaatttaa agtaaaagaa
     4081 gataaacagt gggttttgac tcactgtttt tgattttccc tcaggcatga tataatggat
     4141 aaagaagtct agaaagagga acgatatgaa cgaaatcaaa tgccccaact gtggggaagt
     4201 ctttacagta aatgaaagtc agtatgctga acttttatcc caagtgagaa cagcagagtt
     4261 tgataaggaa gtacatgatc ggatgaagca ggaactggcc ttggctgagc aaaaggccat
     4321 gaatgaacaa cagtctaaac tagctcaaaa agaccaagaa attgctcaat tacagagtca
     4381 aatccaaaat tttgatacag aaaaagaatt ggccaagaaa gaggttgaac agacaagcaa
     4441 tcaggcatta ttggctaagg ataaggaagt acaggccttg gaaaatcaat tggcgacctt
     4501 acgtttggag catgaaaatc aactgcaaaa gaccctttct gacctagaaa aagaacggga
     4561 tcaggtcaaa aatcagcttc ttttacaaga aaaagaaaat gagttgtctt tggcttctct
     4621 taaacaaaac tatgaagcac agctcaaggc agcgagtgaa caggtcgagt tctataagaa
     4681 tttcaaagcc cagcagtcta caaaagctat cggggaaagt ctggaacact atgcagagag
     4741 tgagtttaac aaggtccgca gttttgcttt tccaaatgcc tactttgaga aggataacaa
     4801 ggtctctgcg cgtgggtcta agggtgactt tatcttccgt gaatgtgatg aaaatggggt
     4861 cgaaatcatt tctatcatgt ttgagatgaa aaatgaagcg gacggaacag agaagaagca
     4921 caagaatgca gacttttata aggaattgga taaggaccgt cgggaaaaga actgtgagta
     4981 tgctgttttg gtgaccatgc ttgaggccga taatgattac tttaacacag ggattgttga
     5041 cgtcagtcat gagtatgaaa agatgtatgt ggttcgtccc cagttcttta tccagttgat
     5101 tggtctcttg cgaaatgctg cgcttaattc tttgaaatac aagcaagaat tggctttgat
     5161 tcgggagcaa aatattgaca tcactcattt tgaagaagat ttggacgcct ttaaactagc
     5221 ctttgccaag aactacaact cagcttcgat caactttggt aaagctatcg atgaaatcga
     5281 caaggcaatc aaacgcatgg aagaggttaa gaaattccta acaacatctg aaaaccaact
     5341 ccgccttgca aacaataaat tggaagatgt ttccgtcaaa aaattgaccc ggaaaaatcc
     5401 aactatgaaa gcaaagtttg aagcgctgaa gggggagtag ccttaaatat gaaataactt
     5461 taaaatagtc gtatgtctac attaaatatt tacaacttta tgtacaggaa acgaagagct
     5521 atttaggaag ataaaactga tatgagttct taccgtacgt cacctatgtg aaagagcata
     5581 atcaggttaa taagattatg caacagttaa aactactaac gagactggat tgtcaaaggt
     5641 atatcatgga gaacaggttt taaaagcggt agttgctaca gtttttgtta ttggtacttt
     5701 aattgatggt gttacagtta gtgcatctac atttgtattt ggagttttga tagcgattct
     5761 agtaattgcg agcgacttct tatatttaag ttctacaatg gaggataatg gtgaaagaga
     5821 tattaaataa ctattcgttg aaaatatcta gaattgaaat ttcaaaatta tataatttga
     5881 caaaaatagt atacatttgc ttaattccta tagtttgcct atcatttata ggcatggttg
     5941 ttgaattatt taaaggtggg gaaatgaatt ttatgaaatt cattacttat actgtagtat
     6001 gttttgggtt tgaggcattg ctttcattaa acaataaact ggttaaatta gctgtagata
     6061 atatcttttt gacagatatt aatttcgaaa agcacataaa ttattatcgt tatgtagctg
     6121 aacactccgt taagtctcaa cagctgttca ataattcaaa ttatttacta gctattgccc
     6181 aatcgtcata ctaccaagga aagtttgaag aaacacttga taatttggga cgaataaatt
     6241 ttgaggataa aaattttaat aagaaatttg aaatcgaatt atccacaact tactttaaga
     6301 ttctttctct aatccatgct gataagacag aggaaatttc gcaccaaatc gatatgttag
     6361 ctacattaaa agttcgaaca aattctcagg ttgttaggaa gacgaatgta ataaacataa
     6421 taaaagctat agaggatctt gttttaaata aaaaatcaaa cgactacttc gacattactg
     6481 agccagaaag taagctagct cgaatcatgt tttcttatta cggagctctc aatgcccagc
     6541 taaaaggaga tgaagctcgt gcccgaagtt tgtttgaaag cattgcccat gaaaatccag
     6601 aactctttta tgttcaggaa gctaggaagt atttagaaaa atgagctgat atagttttaa
     6661 aatctgtcta agatagaata tgttgatgta aagtgaaaag ggaattagaa agtaacaaat
     6721 gaacggtatt atcaacttaa aaaaagaagc gggaatgacc tcgcatgatg cggtttttaa
     6781 actgcgtaag attttgggaa ccaagaaaat tggtcatggt gggaccttgg atccggatgt
     6841 agtgggtgtt ttgcccattg cagttggcaa ggcgacccgc atggtcgagt ttatgcagga
     6901 tgagggtaag gtctacgagg gagagattac tctgggctat tccacgacga ctgaggatgc
     6961 tagtggggaa gtggtcgctg agacacccgt tttgtcgccc ttggatgaaa agcttgtcga
     7021 tgaagcgatt gctagtttga ctgggtctat tacccagata ccacctatgt attcagctgt
     7081 taaggttaat ggtcgcaagc tctatgagta tgcgcgtgct ggtcaggaag tggagcgccc
     7141 agaacgtcag gtgactattt atcaatttga gcgaacaagt ccgatttctt atgagggtca
     7201 tattgcacgc tttacttttc gtgtgaaatg tagcaaggga acctatattc gtaccttatc
     7261 ggttgacttg ggagaaaaac ttggctatgc tgcccatatg tcacatttaa cacggactag
     7321 tgcagcgggt ttacagctag aagatgctct taccttggaa gaaattgctg gaaaagtgga
     7381 ggctgaccaa ttgaactttc tccatccttt agagattggg acaggtgacc ttgtcaaagt
     7441 tttcctaact caagaagagg ctatagaagt gcgctttggt cgttttatcg aactcgaaca
     7501 aacagaacaa gaattagctg cctttgaagg cgatacattg ctagccattc tagaaaaacg
     7561 ggacaatctc tacaaaccaa ggaaggtttt tagctaatct atctggagtg tggggatgga
     7621 attcttcccc tagactatcc aaatcagact ataaattttg caaaaaatgt gatagaatag
     7681 acgacggata aaaaaacgga ggatagcatg caaaatagac caatcattat cggagtgaca
     7741 ggtggttctg gtggaggtaa gaccagtgtt tcaagagcca ttttatcgca ttttcctgat
     7801 gaaaaaattt ccatgattga gcatgattca tattacaagg atcagtctca tttgaccttt
     7861 gaagagcgtg tcaaaaccaa ctacgaccat ccatttgcct ttgatacaga cttgatgatt
     7921 gagcagatta aggaattgtt ggcagggcgt ccggtggaca tcccgaccta cgactataca
     7981 gagcatacac gaagcagtaa gacctatcgt caagagcctc aagatgtctt tatcgttgag
     8041 gggattttgg tcttggagga caagcgtctg cgcgatttga tggatatcaa gatttttgtg
     8101 gatacggatg atgatgtgcg cattattcgt cgtatcaagc gtgatatgga agagcgtggc
     8161 cgtagccttg atagcgtcat tgaccagtac ttaggtgtgg ttaaacctat gtaccaccag
     8221 tttatcgaac caaccaagcg ttatgctgat atcgtcattc ctgagggagt cagcaataca
     8281 gtggctatcg acctgttgac gaccaagatt gctaagattt tggaagaagc tcgaaacagc
     8341 aaataatcag atgtggaggc cttgcctcct ttttctattt ttccctcata atggtacata
     8401 aatggagatt tttaggcata tttttggtat aataataccc atgaaagagc aagaaaatga
     8461 atagtaggtg gagatggaaa agtatttatc ggtaacaact ttgaccaagt atctgaaaat
     8521 gaaattcgat aaagaccctt acttggaacg ggtctattta actggtcaag tttccaactt
     8581 tcgtaaacga cctactcacc aatatttctc cctaaaagat gaccatgcag ttattcaagc
     8641 gactatttgg tctgggattt atcagaaatt aggtttcgac ctagaagaag gaatgaaaat
     8701 caatgtgatt gggcgtgtgc aggtctatga accaagtggt agctactcca tcatcattga
     8761 aaaggcagag cctgatggga ttggtacact tgctattcag tttgaacaac tcaagaaaaa
     8821 attgacagaa gagggcctgt ttcaagagag gttcaagcaa cctctgcctc aattttctaa
     8881 gagaattggt gtagtaacca gtcgcagtgg agccgtgatt cgagatatta tcacgactgt
     8941 cagcaggcga tttccaggtg ttgacatact tctttatccg accaaggttc aaggagatgg
     9001 agcagcagag gaaatagcac ggaatattgc gcgtgctaat caacgtgacg atttggattt
     9061 gctgattatt ggtcgtggag ggggttctat cgaggatctc tgggccttta acgaagagat
     9121 tgtggtacgg gctatttttg aatctcgctt gccaatcatt tctagtgttg ggcatgagac
     9181 ggatgtgacc ttggcagatt ttgtggcaga tagacgcgct gcgacgccaa cagctgcagc
     9241 tgaactagca acacctgtga ccaagttgga tctattagct catttgcaaa atcaggaaaa
     9301 acggatggca acagcagtcc gaaatgtcct atctaagaaa caagaagctt tgaaaaaatg
     9361 cagtcagtct gttatcttta gacagccaga gcgtttgtat gatggctatt tgcaacggct
     9421 agaccaatta caactgcgtt taaaacaaag tttgcgaaca cggatttctg ataacaaaca
     9481 gacagtacaa gcaaggacgc atcgactggt acaattatca cccgttacca aaatccaacg
     9541 ctatcaagac cgtctaggtc agttggacaa gcttctccgt agccaaatgg cgctggttta
     9601 tgatgccaag gttgctgaag tcaagagatt atcagaagcc ctactgatgt tggataccag
     9661 tcgtatcgtg gcgcgtggct atgctattgt caagaaagaa gagtccgtag ttgattcggt
     9721 tgaaaatttg aagaaaaaag accaagtgac gcttttgatg cgtgatggtc gagtagaatt
     9781 agaggttaaa gatgtcaaaa caaaagaaat ttgaggaaaa tctagcagaa ctggagacca
     9841 ttgtccaaag tttggaaaat ggtgaaattg ctctggaaga tgcgattgct gcctttcaaa
     9901 agggcatggt cttgtcaaaa gagctccaag cgacgctgga caaggctgaa aagaccttgg
     9961 tcaaggttat gcaagaagac ggaacagaaa gtgattttga atgaaaaagc aagaaaaatt
    10021 agctcatgtt gagtcggctt tggaagactt ttatggcgac cagcagtttt cctctagttt
    10081 gcgagagtct gttctctatt cgattcatgc tggtggcaag cgtattcgac cttttctctt
    10141 gttagaagtt ctggaagcct tgcatattgc catcaaacct gctcatgcgc aggtagctgc
    10201 ggccttggaa atgattcata cagggagctt gatccatgat gatcttccag ctatggatga
    10261 tgatgattac cgtcggggac gcttgacaaa tcataaaaaa ttcggtgaag caatggcaat
    10321 tttggctgga gatgctttgt tcctcgatcc ctatgccttg atagcgcagg cagatttgcc
    10381 aagtcagatc aaggtggact tgattgctaa cttatcccta gcgtcaggaa gtatgggcat
    10441 ggtagcaggc caggttttgg atatggaggg cgaacatcag catttgtctt tggaagaact
    10501 tcagaccatt catgccaata agactggaaa actactagct tatccctttc aagcagctgc
    10561 tattatagcc gaattggcac ctgagatgca ggtgaagctg aaaactgttg gtgaattgat
    10621 tggcctggct tttcaagttc gagatgacgt actggatgtg acagctagtt ttgaggaaat
    10681 cggcaagaca ccccaaaagg atttacaggc tgaaaaatca acctatccag ccttgttggg
    10741 cttggaagag gctattgcct tttgtaacca gactttggat caagctaatg caaaactaga
    10801 ggaaattgct cagcaggtcc cttttgatat aggatcgatt gtaagtgtag tagaaagttt
    10861 gagaatcaat ggctaaggaa agagtggatg tactagctta taaacagggc ttgtttgaaa
    10921 cgcgagaaca agccaagcgc ggtgtcatgg ctggcctagt cgtagcagtc ctgaatggag
    10981 agcggtttga caagccagga gagaaaatcc cagatgacac cgaactaaaa ctcaaggggg
    11041 agaaactcaa gtatgtcagc cgtggtggct tgaaactgga aaaggcattg caggtctttg
    11101 aattgtcagt ggaaggggca acaacgattg atatcggggc ctctactgga ggatttaccg
    11161 atgtcatgtt gcaaaatggt gccgagttgg tctttgcagt cgatgttggt accaatcagt
    11221 tggcttggaa attacgccaa gacccacggg ttatcagcat ggagcagttc aatttccgct
    11281 atgctgaaaa gactgatttc gagcaggaac cgagctttgc cagtattgat gtgagtttca
    11341 tttccctcag tctgattctt ccagccttgc accgagtgct agctgatcaa ggtcaggtgg
    11401 tagcacttgt caaacctcag tttgaggcag gtcgtgagca gattgggaaa aatggaatca
    11461 ttcgagactc caaggttcac cagaatgttc ttgaatctgt cacaactatg gcagtagagg
    11521 aaggtttttc agtccttggt ttggactttt ctcccatcca aggtggacat gggaatattg
    11581 aatttttagc atatttgaaa aaagaagagt cagcaaacaa ttgtgttctt gctgaaattg
    11641 aagaagtagt agagagggcg catagtcaat ttaaaaatga ataaaaaaga gagacttgaa
    11701 aaaattagaa gatttgtgac agattatcaa atcggtacgc aagaagaaat tgtagaacat
    11761 ttgaaagagg caggaatcac tgccactcaa gcaacggtat cacgagatat caaagagcta
    11821 ggtattgtca aaattccttt gagagacaat acctatgtct atgaattgcc aaaatcaatc
    11881 gtgaaaagtt tgcaactggc tgaagacaat atcgaatcgg cagaattgat ggataagatg
    11941 atcaatctcc aagtcatccc aggaaataca gcttttgtaa aagctcagtt aaccgagaat
    12001 ttttctgaca agatttttag ctgtttagct gatgatagct cgattttagt cattgccaga
    12061 agtgaaagtc tagctgagaa aatctttgaa caagtaaaaa attggtaggt ctatatgtta
    12121 cttgaaattt cgataaaaaa ctttgccatt attgaggcta tttccctcaa ttttgaaaag
    12181 gggatgactg tcctgactgg tgaaacgggt gcagggaagt cgattatcat tgatgccatg
    12241 aatatgatgt tgggagctcg tgctacgaca gatgttattc gtcacggtgc gccaaaggca
    12301 gagattgagg gtcttttctc agttgagaat agtcgccttt tacaggaaat ttttgatgag
    12361 caaggtttgg aaatgggaga tgaaatcatc atccgtcgag aaattctgca aaatggtcgt
    12421 agtattagtc gtgtcaatgg ccaaatggtc aatctgtctg ttttgcgtgc tattgggcaa
    12481 catcttgtag atatacatgg tcagcatgac caagaagagt taatgcgccc tcaacttcat
    12541 attcaaatgt tggatgaatt tggtgataca gccttttggg ccttgaaaga aacctatcaa
    12601 acgagttttg atgcctatcg taaaatgcgt aagcaggttc tggaagtcaa gaaaaaccaa
    12661 caggaacaca aggctcgtat tgaaatgttg gaatttcaaa tggcagagat tgaggcagca
    12721 aacttgcaag ctggtgaaga cttatctctc aatcaagagc gagagaaact tctcaaccat
    12781 aaaaacattg cggatacact gaccaatgcc tacagtatgt tggacaatga agatttttca
    12841 agtctggcta atgttcgttc agccatgaat gacatggaaa gtgttgaaga gtacgaccct
    12901 gaataccgtg aaatttcaag ctctttgtct gagacatact atgtcttaga agacattagc
    12961 aaacgtttgg aagcaatcat tgaggacctt gattttgatg gtaatcgtct catgcagatc
    13021 gagaatcgtt tggatctcct tcatactatt acccgtaagt acggtgggac tgttgatgat
    13081 gtcttgcttt attttgccaa gattacggaa gaatacaatc tcttgacagg aaataacctt
    13141 tcgtctgagg acatggaagc agagctcaag aaattggaag ttaatcttgt cgacttggca
    13201 ggtcagcttg catctgctcg tcatgatttg gctcagcagc ttgaagctga gattaaacaa
    13261 gaactgcaag acctttatat ggaaaaagcc cagtttcagg ttcgttttag caagggaaaa
    13321 ttcagtcgtg agggaaatga aatggttgag ttttacattt caaccaaccc tggcgaagac
    13381 tttaaacctt tggtcaaggt tgcttctggt ggggaattat cccgtctcat gctagctatt
    13441 aaatctgcct tttcacgtaa agaaggcaag actagcattg tctttgatga ggtggatacg
    13501 ggagtttcag gccgtgtagc tcaggccctt gcacagaaga ttcacaagat tggccaacat
    13561 ggtcaggttc tggctatttc ccatttgcca caagtgattg cgattgcgga ttatcaattc
    13621 tttattgaga agattagcaa tgagcattca acggtttcga ctgttcgtct cttgacggtt
    13681 gaagagcgag tggaagaagt tgctaagatg ttggcaggtg atgatgtgac ggaagcagcc
    13741 ctgacgcaag ccagagaatt gttgagaaac agggagaaat aagatgacag actattatgt
    13801 aattggagat gttcacggaa aagctgggat gctggaagac cttctcaaaa catgggatgg
    13861 tcagacccag ttgctctttc taggggattt gattgaccgt ggtgaagata gtcgccgtgt
    13921 ccttgaaatg gtcaaggact tggtcgataa tcaaggggca atctgtttgt caggaaacca
    13981 cgagtatatg tttctgactt ggctcgataa cccagaagaa agttatgacc attatcgtcg
    14041 caatggtgga gatacaacca ttaactctat cctaggtcgt cccttggatg caccagttga
    14101 tggggtagaa gatgccaagc gggttaccac tgaagcggca gacttggtcg aatttattcg
    14161 tcaaatgccg tttgtggtag agacagataa gtatatcttt gttcacgcag gtattgattt
    14221 gaccttagac gactggcatg aaaccacaga ttacaagaaa gtctggctta gaaaaccatt
    14281 ccacgaagcc gaaaatcata ctgggaaaac tattgtcttt ggtcacacac cagtttatgg
    14341 tttgttgaat caagatcgag gtacagctga gctttggact acagaagatg gcaagattgg
    14401 gatggacgga ggagctgtct atggtggtgt ccttcacggg attgtcttta cagaccaagg
    14461 aatgacagaa caccacttta tcgaaaatga cggctttgtc gctgaagatt agtactccta
    14521 acagggtatg gtcttgtcaa aatgtcaaaa acaatttata ataaatagat accctgaaag
    14581 gaagagaatc atgaacttag aagaattgaa aaaacgacag gagaagatcc ggaacttctc
    14641 tattatcgcc catattgacc acgggaaatc aactttagca gaccgcattt tggaaaagac
    14701 agagacagta tctagtcgtg aaatgcaggc ccaacttctg gatagtatgg accttgagcg
    14761 tgaacgtggg attaccatta aactcaatgc tatcgagctg aattatactg caaaagatgg
    14821 ggaaacttat attttccact tgattgacac gccggggcac gtagacttta cctatgaagt
    14881 gtcacgttcg ctagctgcct gtgagggagc gattttggtg gtcgatgctg cccaagggat
    14941 tgaggctcaa acccttgcca acgtttatct ggccttggac aatgatttgg aaatcatgcc
    15001 agtcattaac aaaattgacc taccagctgc agatcctgag cgcgtgcgta cagagattga
    15061 agatgtgatt ggtttggacg ccagtgaagc agttttggct tctgccaagg ctggtattgg
    15121 tatcgaagaa attctagagc aaattgtaga aaaagtacca gcaccaacgg gtgatgtgac
    15181 ggcgccactt aaggccttga ttttcgactc ggtttacgat gcttaccgtg gggttattct
    15241 tcaagtgcgt gtcatggatg gggtggtcaa acctggtgat aagattcagc ttatgagcaa
    15301 cggcaagacc tttgatgtga ccgaagtcgg tatatttaca cccaaagcag ttggtcgtga
    15361 tttccttgcg actggtgacg ttggatatat cgctgcatct atcaagacag ttcaggatac
    15421 tcgtgtgggt gataccgtta ccttggcaac caatcctgcg gcagagccat tacatggtta
    15481 caagcagatg aatcctatgg tctttgcggg gctatatcct atcgagtcaa acaagtacaa
    15541 tgacctacgt gaagcccttg aaaaattgca actgaatgat gctagtctcc aatttgaacc
    15601 agaaacatct caggcacttg gatttggttt ccgttgtggt ttccttggac ttctccatat
    15661 ggatgttatc caagaacgtt tggaacgtga gttcaacatc gacctcatca tgacagctcc
    15721 atccgttatc tataaggtta atttgactga cggtgagtct atggatgtgt ccaacccgtc
    15781 tgaattccca gatcctacca agattgcgac cattgaagag ccttatgtta aggcgcaaat
    15841 catggtacca caggagtttg tcggagcagt gatggagcta gctcagcgca agcgtgggga
    15901 ctttgtgact atggactata ttgatgataa tcgtgtcaat gttatctatc aaattccact
    15961 ggctgaaatc gtctttgact tctttgataa acttaagtct tcgacacgtg gttatgcaag
    16021 ttttgactac gaattgtcag aatatcgccc atctaagctg gtgaaaatgg atatccttct
    16081 caatggagac aaggtggatg ccctcagctt tatcgttcac aaggactttg cctacgaacg
    16141 tgggaaactc atcgttgata agctcaagaa aatcattcct cgccaacaat ttgaggttcc
    16201 tatccaagca gcaattggac acaagattgt ggctcgtact gatatcaagg cccttcgtaa
    16261 gaacgtactt gctaaatgtt atggtggtga cgtttctcgt aaacgtaaac tccttgaaaa
    16321 acaaaaagct ggtaagaaac gtatgaaagc tatcggatca gtagaagttc cacaagaagc
    16381 cttcctcagc gttttgagca tggatgaaga gtagaagtat aaagaaaagc attttattgt
    16441 tgatagactt taaatatcaa acaacaaaga taaataaaag aagatcaaat ggtcttcttt
    16501 tttatttgtt ttacgaataa atagatgagt agaaaaagaa atggagatat ttatgaaaat
    16561 cacaaactat gaaatctata agttaaaaaa atcaggtttg accaatcaac agattttgaa
    16621 agtcctagaa tacggtgaaa atgttgatca ggaacttttg ttaggtgata ttgcagatat
    16681 atcaggttgc cgaaatccag ccgtttttat ggaacgttat tttcagatag acgatgcgca
    16741 tttggagaag gagtttcaaa aatttccatc tttctctatt ttagatgact gttatccttg
    16801 ggatttgagt gaaatatacg atgcacctgt gcttttattt tacaagggaa atcttgacct
    16861 cttgaaattt cctaaagtag cagttgtggg gagtcgtgct tgtagcaaac agggagctaa
    16921 gtcagttgaa aaagtcattc agggattgga aaatgaactg gttatcgtca gtggattagc
    16981 taagggcatt gatacagcag ctcatatggt agctcttcag aatggcggca aaaccattgc
    17041 agtgattgga acaggactag atgtatttta tccaaaagcc aataaacgct tgcaagacta
    17101 catcggtaat gaccatctgg ttcttagtga atatggacct ggcgaaaaac ctctgaaatt
    17161 tcattttcct gcccgtaatc gcatcattgc tggactttgc cgtggtgtga ttgtagcaga
    17221 ggctaagatg cgctcgggga gtctcattac ctgtgagcga gcaatggagg aagggcgcga
    17281 tgtctttgct attcctggta gcattttaga tggactatca gacggttgcc atcatttgat
    17341 tcaagaaggg gcaaaattgg ccaccagtgg gcaggatgtt cttgcagaat ttgaatttta
    17401 atactcttcg aaaatcaaat tcaaaccacg tcagcttcac cttgccgtac tcaagtacag
    17461 cctgcggcta gcttcctagt ttgctctttg attttcattg actataagaa gaaagtccgc
    17521 ttactaaaca aacttttctt ctatatatag gagctaagtc ttgacagtta tggcaaaatg
    17581 gtttacactt tataaagttt attactttga aaaggtgtga tactgtggct acggcaacaa
    17641 aaaagaaaaa atcaacagtt aaaaaaaatc tagtaatcgt ggagtcgcct gctaaggcta
    17701 agacgattga aaaatatctc ggcagaaact acaaggtttt agccagtgtc gggcatatcc
    17761 gtgatttgaa gaaatccagt atgtcagtcg atattgaaaa taattatgaa ccgcaatata
    17821 tcaatatccg aggaaaaggc cctcttatca atgacttgaa aaaagaagcc aaaaaagcta
    17881 ataaagtctt tctggcgagt gacccggacc gtgaaggaga agcgatttct tggcatttgg
    17941 ctcacattct caacttggat gaaaatgatg ccaaccgtgt ggtcttcaat gaaatcacta
    18001 aggatgcggt caaaaatgct tttaaagaac ctcgtaagat tgatatggac ttggtcgatg
    18061 ctcaacaggc acgccgtgtc ctggaccgct tggtagggta ttcgatttcg cctattttgt
    18121 ggaagaaggt caagaagggc ttgtcagcag gtcgcgttca gtctattgcg cttaagttaa
    18181 tcattgatcg tgagaatgaa atcaacgcct ttcagccaga agaatactgg acaattgatg
    18241 gtgtctttaa aaagggaacc aagcaatttc aggcttcctt ctatggagtg gatggtaaaa
    18301 aactgaaact gactagcaat gatgaggtca aggaagtctt gtctcgtctg actaataaag
    18361 acttttcagt ggatcaggtg gataagaaag agcgcaaacg caatgctcct ttaccctata
    18421 ccacttcatc tatgcagatg gatgcggcca ataaaatcaa tttccgtact cgaaaaacca
    18481 tgatggttgc ccaacagctc tatgaaggaa ttaatatcgg ttctggtgtt caaggtttga
    18541 ttacctatat gcgtaccgat tcgactcgta tcagtcctgt agcgcaaaat gaagcagcaa
    18601 gtttcattac ggaccgtttt ggtagcaagt attctaagca tggtagcaag gtcaaaaatg
    18661 catcaggtgc tcaggatgcc catgaggcta ttcgcccgtc tagcgttttt aatacacctg
    18721 aaagcatcgc taagtatctg gacaaggatc aactcaagct ttatactctt atttggaatc
    18781 gttttgtggc tagccagatg acagctgctg tctttgatac catggctgtt aaattgtctc
    18841 aaaatggggt tcaatttgct gctaatggta gtcaggttaa gtttgatggt tatcttgcca
    18901 tttacaatga ttctgacaag aataagatgt taccagatat ggctgttgga gatgtggtca
    18961 aacaggtcaa tagcaaacca gagcaacatt tcactcaacc gcctgctcgc tattctgaag
    19021 cgacactgat caagaccttg gaggaaaatg gggttggacg tccgtcaacc tacgcaccta
    19081 ccattgaaac cattcagaaa cgttattatg ttcgccttgt agccaaacgt tttgaaccga
    19141 cagagctggg agaaattgtc aacaagctca tcgttgaata tttcccagat atcgtaaacg
    19201 tgaccttcac agctgaaatg gaaggtaaac tggatgatgt cgaggtcgga aaagagcagt
    19261 ggcaacgcgt tattgacgcc ttttacaaac cattctctaa agaagtcgca aaggctgaag
    19321 aagaaatgga gaaaatccaa atcaaggatg aaccagctgg atttgactgt gaagtgtgtg
    19381 gcagtccaat ggtcattaaa cttggtcgtt ttggtaagtt ctacgcttgt agcaatttcc
    19441 cagattgccg tcatacccaa gcaattgtga aagagattgg tgttgagtgt ccaagttgtc
    19501 atcagggaca aatcattgag cgtaaaacca aacgtaaccg cctcttctat ggttgcaatc
    19561 gctatccaga atgtgaattt acctcttggg acaagcctgt tggtcgtgac tgtccaaaat
    19621 gtggcaactt cctcatggag aaaaaagtcc gcggtggtgg caagcaggtt gtttgtagca
    19681 aaggcgacta cgaggaagaa aagattaaat aagaggagtg tcctgaaagt taatttcagg
    19741 ctcttttggt tagaacttga caaaattcat cattgtatgc gaaactagaa gaagattatt
    19801 ttatactcaa tgaaaatcaa agaacaaact aggaaactag ccgcaggttg ctcaaagcac
    19861 tgctttgagg ttgcagataa gactgacgaa gtcaggaacc atacctacgt caaggcgacg
    19921 ttgacgcggt ttgaagagat tttcgaagag tattaactag gagaagttat gcgtcttatc
    19981 tatctaataa ttggtttttt atcactagcc ttggctattg ttggggtagt tttacccttg
    20041 ttgcccacaa cgccttttct tttgttgtct attgcttgtt tctctagaag ttccaagcgc
    20101 ttcgaagatt ggctttatca taccaagctc tatcaaacat atgtagctga ttttcgggag
    20161 actaagtcta tcgcgcgtga acgtaaaaaa aagattattg tctctatcta catcttgatg
    20221 ggaatttcca tttattttgc acctctttta ccagtcaaaa tcggtctggg tgctttgacc
    20281 atctttatca cctattatct cttcaaggtc attccagaca aagaatagtt aaaatagtag
    20341 ttatttgcct tgataaaatt gaaagcatat ccacaacaat atgatataat aaatttaaag
    20401 taatcttcaa ggagaatcaa atgatttacg aattttgtgc tgaaaatgtg accttgcttg
    20461 aaaaagcgat acaggctgga gctcgtcgaa tcgaactctg tgataatcta gcagtgggag
    20521 gaacaacacc aagctatgga gtgaccaagg cagcggttga attggcagct aactacgata
    20581 cgaccatcat gaccatgatt cgtccacgtg gtggtgactt tgtctataat gaactagaaa
    20641 ttgcaattat gctagaagac attcggttga ctgctcagac tggaagtcaa ggggttgtat
    20701 ttggggcttt aactgctgat aagaagttgg ataagcctaa tcttgaaaag ttaattgctg
    20761 catcaaaagg aatggaaatt gtcttccaca tggcctttga tgaattgagc gatgaagatc
    20821 aactggaagc tattgactgg ctcagtcaag ctggaatcac tcgaatcctg actcgt
//
