LOCUS       NZ_CP053892            21389 bp    DNA     circular CON 05-MAY-2024
DEFINITION  Actinomadura verrucosospora strain NRRL:B18236 chromosome.
ACCESSION   NZ_CP053892
VERSION     NZ_CP053892.1
KEYWORDS    RefSeq.
SOURCE      Actinomadura verrucosospora
  ORGANISM  Actinomadura verrucosospora
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 10214634)
  AUTHORS   Samborskyy,M.
  TITLE     Actinomadura verrucosospora NRRL-B18236 (PFL_A860) Genome sequencing
            and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10214634)
  AUTHORS   Samborskyy,M., Dickens,S. and Scott,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAY-2020) Biochemistry, DNA Sequencing Facility,
            University of Cambridge, 80 Tennis Court Road, Cambridge,
            Cambridgeshire CB2 1GA, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-DEC-2016
            Assembly Method                   :: Newbler v. 3.0
            Assembly Name                     :: A860_AS2.mpe1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013211575.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 03:37:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,277
            CDSs (total)                      :: 9,181
            Genes (coding)                    :: 9,110
            CDSs (with protein)               :: 9,110
            Genes (RNA)                       :: 96
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 18 of 71
            Pseudo Genes (incomplete)         :: 57 of 71
            Pseudo Genes (internal stop)      :: 2 of 71
            Pseudo Genes (multiple problems)  :: 6 of 71
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:15:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 10173239
            Orig. end                         :: 10194628
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP053892.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Peter Leadlay,
            NRRL-B18236 (patent collection, not in online catalogue).
FEATURES             Location/Qualifiers
     region          1..21389
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="35"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21389
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21389
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11389](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11389)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    39..53
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.9"
                     /tool="antismash"
     gene            complement(240..845)
                     /locus_tag="ACTIVE_RS46070"
                     /old_locus_tag="ACTIVE_9241"
     CDS             complement(240..845)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012852480.1"
                     /locus_tag="ACTIVE_RS46070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9241"
                     /product="DUF3105 domain-containing protein"
                     /protein_id="WP_173100836.1"
                     /transl_table=11
                     /translation="MSKSARNKQARKKNALTQRQVPWGGIAFFTVIGLVAVVAIGYAFL
                     QSRPSSADTASIAGVTVKEGLSRDHTADSVKYDGNPPMGGDHDPVWQNCDGRVYDQALR
                     NENAVHSLEHGAVWITYRPGLAAAQLDALKAKVERTDYTFLSPYPSLDAPIALTAWGHQ
                     LKLQDAGDARVDRFLRAYVKGPQTPEPGAACDGAKDTP"
     gene            complement(952..1416)
                     /locus_tag="ACTIVE_RS46075"
                     /old_locus_tag="ACTIVE_9242"
     CDS             complement(952..1416)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS46075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_9242"
                     /product="hypothetical protein"
                     /protein_id="WP_173100837.1"
                     /transl_table=11
                     /translation="MSGTAHRRRHGQAGLLVALFVVAGLVFSYGLGHALPDRVCIENGM
                     SVPAEVATAMHHASTSPGGPAAHPAAVHGVPGHAGTAAASLSAPLRLPPLAPADACLCL
                     AVLFALMLLGLATGRRALLRLPARAPRAPAPPPGGVLSPISLASLQVLRL"
     gene            1563..2357
                     /locus_tag="ACTIVE_RS46080"
                     /old_locus_tag="ACTIVE_9243"
     CDS             1563..2357
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025736.4"
                     /locus_tag="ACTIVE_RS46080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9243"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_173100838.1"
                     /transl_table=11
                     /translation="MRRSGGTEAILRRELTGRRLVAATAVQVLVMGVVIGAYELGRHFA
                     DGRPGDAFAHARWLWDLERTLRLPDESAFQKWALGWDGWVRAANEYYVRVHFPAILLFM
                     AWMWFRHREGWPRVRAVIAITAAAALALHFAFPLAPPRMLPGHGFIDLMNVYGPSSYSS
                     KPGEGMANQFAAMPSLHVGWALLVAWGAIRYGGGRLRYIMALHPVLTFLIVVVTANHYW
                     TDGIVGCTIVIVTLWATSKVPALADRTPERAGVSLPRDSVGA"
     gene            2495..3754
                     /locus_tag="ACTIVE_RS46085"
                     /old_locus_tag="ACTIVE_9244"
     CDS             2495..3754
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017625759.1"
                     /locus_tag="ACTIVE_RS46085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9244"
                     /product="replication-associated recombination protein A"
                     /protein_id="WP_246343244.1"
                     /transl_table=11
                     /translation="MRPRALDEVVGQGHLLGPGTPIRQLVDRDVPMSLVLWGPPGTGKT
                     TLATVVSHVTSRRFVEISAVSDGVKRVRAEIDLARRELGMTGRQTVLFVDEVHRFNKAQ
                     QDALLPAVENRWVSFIGATTENPFFSVISPLLSRSLLLTLEPLGDDDLREVIRRALADE
                     RGLNGTVGLDPAAENHLIRLAGGDARRTLTYLEAAALVVDEGAVIDADVLEKAVDRAAV
                     RYDREGDQHYDVISAFIKSIRGSDVDAALHYLARMIEAGEDARFIARRLIVHASEDVGM
                     ADPTALQTAVAAAQAVEFVGLPEARINLAQAVIHLSLAPKSNAVIRAVDGALGDVRKGL
                     AGPVPGHLRDAHYKGAAKIGHGKGYKYAHDHPGGVVRQQYAPDAVDGREYYSPTRHGAE
                     SRFTEVLARIRSVLRGAPGR"
     gene            3982..4401
                     /locus_tag="ACTIVE_RS46090"
                     /old_locus_tag="ACTIVE_9245"
     CDS             3982..4401
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657995.1"
                     /locus_tag="ACTIVE_RS46090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9245"
                     /product="DUF948 domain-containing protein"
                     /protein_id="WP_173100840.1"
                     /transl_table=11
                     /translation="MLTGGQLAGLIVAVFWAVLVAFVALTLLRLARLLGEASKLVRDLG
                     DQAAPLLDDMTTTVKRANEQLGRTDVITKQVAGVTQNVSAVTTVMTSVVGGPLVKAAAF
                     SYGVRKALSSRDGDGRGAASGRPQLQARSSGKGRR"
     gene            4398..4718
                     /locus_tag="ACTIVE_RS46095"
                     /old_locus_tag="ACTIVE_9246"
     CDS             4398..4718
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634490.1"
                     /locus_tag="ACTIVE_RS46095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9246"
                     /product="DUF6167 family protein"
                     /protein_id="WP_173100841.1"
                     /transl_table=11
                     /translation="MKRLFWLSVGAGAGVYATHRVKRRVERFARSWSPEGVAARAVSSG
                     QSAGERMRLFAADVRTGMQAREEELREAVRMDQAPPESPGARPRRVLRARYTIIDDEKD
                     GH"
     gene            4721..7390
                     /gene="alaS"
                     /locus_tag="ACTIVE_RS46100"
                     /old_locus_tag="ACTIVE_9247"
     CDS             4721..7390
                     /EC_number="6.1.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="alaS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011292493.1"
                     /locus_tag="ACTIVE_RS46100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9247"
                     /product="alanine--tRNA ligase"
                     /protein_id="WP_173100842.1"
                     /transl_table=11
                     /translation="MESAEVARRFLKFFEERGHTVVPSASLVAEDPTLLLVNAGMVPFK
                     PYFLGQRTPPSQRMTSAQKCVRTPDIDEVGKTTRHATFFQMLGNFSIGDYFKEQAIPFA
                     WELLTRSREDGGFGFPEDRLWVTVFHDDDEARDLWHNKVGVPLERIQKRGMEDNFWSMG
                     VPGPCGPCSEIYYDRGPEYGREGGPVADEDRYLEVWNLVFMQFERGPGDSKTDFPILGD
                     LPAKNIDTGMGLERMAAVLQGVDNIYETDTLWRVLDRAANLTGTSYGREHRADVSLRVI
                     ADHVRSGTMMVADGIRPGNEGRGYVLRRILRRSIRNLRLLGGQEAGLMHELTSVAIAAM
                     GEQYPELIRTAANIHTVIDAEEESFLQTLRTGTAIFDTAVAETRRSGGGTLAGDQAFKL
                     HDTYGFPIDLTLEMASEAGLQVDEDGFRRLMKEQRDRAKQDARDKKTGNLDVSVLDELL
                     TGAGGKVDFIGYHDVTADARLVGLLVNGANAPAAGEGTEVEVVLDRTPFYAEGGGQLAD
                     QGVIRLGNGAVIDVHDVQSPLAGLIVHRGRVRSGEAQAGDSAHAEIDLTRRAAISRSHT
                     ATHLVHAGFRRALGESAAQAGSENSPGRFRFDFTASGAVPASVLRDVEDEVNEVLVGDL
                     DVRAFHTSIDEARAMGALALFGEKYGDEVRVVEVGDYSRELCGGTHVARSGQLGLVKVL
                     GESSIGAGVRRVEALVGIDAFRFLARESVLVAQLAEQMKARKEELPERISGVVGRLREA
                     EKELEKLRSQQILAVAGSLADGAKDVNGTAFVGHRAPDGTGADDLRKLAVDVRGRLQAR
                     PAVVMVTGVPKDRPVVVVAVTQGARDRGLKAGALVGLAARTLGGGGGGKDDLAQGGGAN
                     PAAIDDALAAVERAVGAA"
     gene            7484..7942
                     /gene="ruvX"
                     /locus_tag="ACTIVE_RS46105"
                     /old_locus_tag="ACTIVE_9248"
     CDS             7484..7942
                     /EC_number="3.1.21.10"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ruvX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017573440.1"
                     /locus_tag="ACTIVE_RS46105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9248"
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="WP_151539443.1"
                     /transl_table=11
                     /translation="MRQGVRLGVDVGSVRVGVARCDPGGILASPLETVKSGRGDIDRLV
                     ELVAEHEAIEVVVGLPTSLSGREGPAAQSARKFAARLADRLPPEAVRLYDERLTTVTAE
                     SGLRAGGVRGQARRKVVDQAAAAVLLQAALDGERLTGRPPGEIVRGSS"
     gene            7939..9108
                     /gene="mltG"
                     /locus_tag="ACTIVE_RS46110"
                     /old_locus_tag="ACTIVE_9249"
     CDS             7939..9108
                     /GO_function="GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="mltG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634493.1"
                     /locus_tag="ACTIVE_RS46110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9249"
                     /product="endolytic transglycosylase MltG"
                     /protein_id="WP_173100843.1"
                     /transl_table=11
                     /translation="MNDLDLFSDPYGDPYDEGQPQEPPSRRDRRRARKRQRRRRRSGRA
                     AFLFALAFIVAVFGTAGVFGAAILDNRLHPPDYSGSGSGNVTVQVKDGASGAVIGATLQ
                     EHHVVKSTRAFVKVYNGESRASSIQPGFYQMRREMSSKAAMALLLDPKSRAGNQITIPE
                     GKRAIEIFELLSKKTGIPVRDFQAVAKNTKGLGLPSYSGGKLEGFLYPGRYDLDPNGSA
                     RKIVQQMVDAFNKEASSSDLENKAKKAGLSPLRLLTVASLAQAEGGKPSDLPKISRVIY
                     NRVKSGMALQFDTTVLYALNKRTLDVRNKDLEVDSPYNTYKHKGLPPGPICNPGPDAIE
                     AALSPKSGEWLYFVATDPTHKITEFAVTDAQRQRLEQKFRDWQAKHPGN"
     gene            9133..9990
                     /locus_tag="ACTIVE_RS46115"
                     /old_locus_tag="ACTIVE_9250"
     CDS             9133..9990
                     /EC_number="1.1.1.25"
                     /GO_function="GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013154088.1"
                     /locus_tag="ACTIVE_RS46115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9250"
                     /product="shikimate dehydrogenase"
                     /protein_id="WP_173100844.1"
                     /transl_table=11
                     /translation="MEAGETGGTRRAAVLGSPIAHSLSPVLHRAAYAAMGLDGWRYGAV
                     ECGEDGLAPLLDGLGPEWAGLSLTMPLKRVALKLADSVSDLAGRVGGANTLVLRDGRRH
                     ADNTDVHGIVTALTEAGLGSPGSAVVLGGGATAASALAALAELGLDAAVLAVRDPGRAS
                     EAAEVGERCGLSVRVATLDRVADHLPAGLVVSTLPGRAADAFAGPVAASGAALFDVVYA
                     PWPTALAAAVERAGGTVVGGFAMLLHQAVRQVELMTGRDDVPVAAMRAAGEAELARRAA
                     APAG"
     gene            complement(10001..11389)
                     /locus_tag="ACTIVE_RS46120"
                     /old_locus_tag="ACTIVE_9251"
     CDS             complement(10001..11389)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012647.4"
                     /locus_tag="ACTIVE_RS46120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9251"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_173100845.1"
                     /sec_met_domain="T2TS (E-value: 4.2e-13, bitscore: 47.7,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQTPQPPQPPAPAPRAAPLAPASSGARAAPAIDMAVLQARLDES
                     LDVLRDTYAPAPGSGGGWYHELARPEPGTTATTLGLLAFVEAGRPFEHFDAGLAFLAER
                     QATSADALRDGGWATRTSLGMPVVEATGWIARFLARARCDLREDAPDLRRAYRWLLRNQ
                     NPDGGWGSLYGCASRVWQTCLALRALAQLNPYDPAVDRGVEWLTAGRTAHRPAWGPVPA
                     AAATVTHTAFVLVTLAEARPGLRSERLLDAYDWLLAHLDPDDDHTWIETYEVSPHGLGS
                     RPVWRLALWHYGLPIALTALLHDPRGPHGPTIARAFRTLVRGEVADPRRNGPPGGGRTS
                     LWTLWWRLETLIALTRVPLAGGADVLHWFPDATVVQRAHARERPVAALLPHRRLADPVA
                     FARRHWPALVLGFVCVSSAFGVKLGAWGWRDFWLSVIVPIVLASVDESLKRRRTPRGPP
                     PAAP"
     gene            11516..12238
                     /locus_tag="ACTIVE_RS46125"
                     /old_locus_tag="ACTIVE_9252"
     CDS             11516..12238
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS46125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_9252"
                     /product="hypothetical protein"
                     /protein_id="WP_173100846.1"
                     /transl_table=11
                     /translation="MRPRVLEEALAEPSAQPGRECVLCPPLRFRINAMAGLPGDPSVLA
                     RDRDFLLMPDVAPLADGHVLLVTREHHQCAGDFDARLWGRALRWRDRVSRLYRYAYGTG
                     ELLLFEHGPALSQGGGACIDHAHWHFLPGTPGVRDVVEECGLPGTPAEFAALRARFRTG
                     RSYLLVEERGTATVHPGDGVRGQFLRWAVTAALGSAEPWRWQETFGLPGSRRCFLRTLR
                     TLRRAAAALDGPPPCEHR"
     gene            complement(12266..12763)
                     /locus_tag="ACTIVE_RS46130"
                     /old_locus_tag="ACTIVE_9253"
     CDS             complement(12266..12763)
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012514.4"
                     /locus_tag="ACTIVE_RS46130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9253"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_173100847.1"
                     /transl_table=11
                     /translation="MPSPETGSPGPATASPPVRLQFAQKAFITSAGRLLMVRKAVSDPF
                     QPGRWEVPGGRLDVGGDLDLDDHIRREVWEEVGLKIDPGPPFHLWQWFMDDRSPGAGGG
                     TVRVVAAARRCRPLTLDVRFGNQDESDHLDGCAWVPLGEVWSYPLIPSLRPVVRAFLPA
                     AR"
     misc_feature    12858..12872
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.14"
                     /tool="antismash"
     misc_feature    13037..13051
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.9"
                     /tool="antismash"
     gene            13324..13881
                     /gene="infC"
                     /locus_tag="ACTIVE_RS46135"
                     /old_locus_tag="ACTIVE_9255"
     CDS             13324..13881
                     /GO_function="GO:0003743 - translation initiation factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="infC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013132287.1"
                     /locus_tag="ACTIVE_RS46135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9255"
                     /product="translation initiation factor IF-3"
                     /protein_id="WP_281382898.1"
                     /transl_table=11
                     /translation="MNDRIRVPEVRLVGPNGEQVGIVPIAKALELARESDLDLVEVAPT
                     ARPPVAKLMDYGKFKYESAMKAREARKNQAHTIIKEIKLRPKIDPHDYETKKGHVVRFL
                     KAGDKVKVTIMFRGREQSRPELGFRLLQRLADDVEELGFVESRPKQDGRNMIMVLGPHK
                     KKAEAKAERAASREQDAATGPA"
     misc_feature    13917..13926
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            14256..14450
                     /gene="rpmI"
                     /locus_tag="ACTIVE_RS46140"
                     /old_locus_tag="ACTIVE_9256"
     CDS             14256..14450
                     /GO_component="GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpmI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005319593.1"
                     /locus_tag="ACTIVE_RS46140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9256"
                     /product="50S ribosomal protein L35"
                     /protein_id="WP_067468638.1"
                     /transl_table=11
                     /translation="MPKTKTHSGAKKRFKLTGSGKVMRRRANKNHLLEHKPTKRTRRLS
                     GPAVVADADAKNIKKLLRK"
     gene            14520..14888
                     /gene="rplT"
                     /locus_tag="ACTIVE_RS46145"
                     /old_locus_tag="ACTIVE_9257"
     CDS             14520..14888
                     /GO_component="GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rplT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013154085.1"
                     /locus_tag="ACTIVE_RS46145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9257"
                     /product="50S ribosomal protein L20"
                     /protein_id="WP_151544049.1"
                     /transl_table=11
                     /translation="MARVKRAVNAAKKRRVVLERSSGYRGQRSRLYRKAKEQQLHSMTY
                     AFRDRKDRKGQFRRLWIQRINAAARANGITYNRFIQGLKAAEVEVDRRMLAELAVNDAP
                     AFAALVKVAKDALPAEAA"
     gene            14923..15738
                     /locus_tag="ACTIVE_RS46150"
                     /old_locus_tag="ACTIVE_9258"
     CDS             14923..15738
                     /GO_function="GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011292486.1"
                     /locus_tag="ACTIVE_RS46150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9258"
                     /product="RNA methyltransferase"
                     /protein_id="WP_173100848.1"
                     /transl_table=11
                     /translation="MAGRELTSIRSPRVKAARRLAKRAFRRREGRFLAEGPQAVREALE
                     IPGGLAELFTTAEAEARHPELVAAAERAGVPVLRVSGEIMAELAQTVTPQGLLAVCGFV
                     DVPLAGALESGPRLVTVLAHVRDPGNAGTVLRTADAAGSETVVFTDASVDPYNGKCVRA
                     SAGSLFHLPVVVGPRFDTLIPELKKSGLTVLAADGAGDRTLDEAIDQGLLARPTAWVFG
                     NEAWGLPEEILRHVDEVVRVPIYGRAESLNLATAAAVCLYASARAQRRA"
     gene            16045..16620
                     /locus_tag="ACTIVE_RS46155"
                     /old_locus_tag="ACTIVE_9259"
     CDS             16045..16620
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657981.1"
                     /locus_tag="ACTIVE_RS46155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9259"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_173100849.1"
                     /transl_table=11
                     /translation="MTEETRPARRPGRRAPEIRCRTGAGQAAPLGSAAPGTTTAGTPAP
                     GAVARGDGASAAVALDAAGAWAPGPVAGLVVEVAERRPGTAVVTVTGEIDLHTADGLRS
                     RLVKAHAAGARQLVLDFAAVPFCDAAGLGALVGAHNEISPSGGEIVLAGVRPAQLRLLR
                     ITGLHRLFALHADVEAALAGQDSPTGSR"
     gene            16885..17952
                     /locus_tag="ACTIVE_RS46160"
                     /old_locus_tag="ACTIVE_9261"
     CDS             16885..17952
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017540385.1"
                     /locus_tag="ACTIVE_RS46160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9261"
                     /product="ATP-binding protein"
                     /protein_id="WP_246342599.1"
                     /transl_table=11
                     /translation="MAARALSGPEQADDLPDGLLVADRDARVVVFNTAAERMTGIAAAA
                     ALGCDFRDVLPLHDAEGRDWWKCLAPYDGLPTRTRHPERSLFLPGGTELLVTAGYRRGD
                     GGRVERFSVCMRDAQRRARQERDRADLVSTVAHELRSPLTSVKGFTATLLAKWHRFNDD
                     QKRVMLETVNADADRVTRLITELLDVSRIEAGRLEMRRQVVDLPDEVRKVIAGRVAAGD
                     AEDRFRFEVRGALPEMWLDPDKMDQILGNLVENAVRHGAGTVTIVVEPDAHKEGAAVSV
                     RDEGEGIPPEAVQRVFRQFWRGPGGNRRGGTGLGLYIVKGLVEAHGGAITVRRAPGGGA
                     EFRFTVPAGAPDHAS"
     gene            18085..19194
                     /gene="pheS"
                     /locus_tag="ACTIVE_RS46165"
                     /old_locus_tag="ACTIVE_9262"
     CDS             18085..19194
                     /EC_number="6.1.1.20"
                     /GO_component="GO:0009328 - phenylalanine-tRNA ligase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pheS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011292484.1"
                     /locus_tag="ACTIVE_RS46165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_9262"
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="WP_173100851.1"
                     /transl_table=11
                     /translation="MSAPNKSYDPVEVSALQPEQLDAARDEALAAIAAAADLDALKQVR
                     LAHAGDRSPLALANREIGALPPAARADAGKRIGAARGAVSKALKERQAALEEERDQRVL
                     VEETVDVTLPWDRAPRGARHPLTTMQERMADVFVAMGFEVSEGPEVEAEWFNFDALNFL
                     PDHPARTMQDTFFVESEESGLVMRTHTSPMQIRSLLSRPLPVYVVAPGRTFRTDELDAT
                     HSPVFHQLEGLAVDEGLTMADLRGGIDAFVTGMFGAGLKTRFRPSYFPFTEPSAEVDMQ
                     CFVCRGASAEPGGEPCRTCGSEGWIELGGCGMVNPRVLVACGVDADRYSGWAFGLGVER
                     TLMFRHGVEDMYDMVEGDVRFTLPFGMEI"
ORIGIN
        1 caggcggacg gcggggtcgg acgtccggtc ccggacgatg aacgacatct ccacggcctg
       61 cgcgtggtgg gcgcccatgt cgcgggcgaa cccggcctcg ggcccgtcgg cggccggttc
      121 gccggacctc caggccgccg tcccgagcag cgccgccgcg gcgagcagga ccagcgcggc
      181 gatggcgacg gtcacgcgcc ggccgcgggg ccggacggcg ccttcctgtt cggtgccggt
      241 cacggggtgt ccttggcgcc gtcgcaggcc gcgcccggct cgggcgtctg cgggcccttg
      301 acgtaggcgc gcaggaaccg gtcgacgcgc gcgtccccgg cgtcctggag cttcagctgg
      361 tggccccacg cggtgagggc gatcggcgcg tccagcgacg ggtacgggct caggaacgtg
      421 tagtcggtgc gctcgacctt ggccttcagc gcgtccagct gggcggccgc caggccggga
      481 cggtaggtga tccacacggc gccgtgctca agggagtgga cggcgttctc gttgcgcagc
      541 gcctggtcgt agacgcggcc gtcgcagttc tgccagacgg ggtcgtggtc gccgcccatg
      601 ggcgggttcc cgtcgtactt gacggagtcg gcggtgtggt cgcgggacag gccttccttg
      661 acggtgacgc ccgcgatgga cgccgtgtcg gcggacgacg gcctggactg caggaacgcg
      721 tagccgatcg cgacgaccgc gaccaggccg atgacggtga agaaggcgat gccgccccac
      781 ggcacctgcc gctgcgtcag ggcgttcttc ttccgggctt gcttgttgcg ggcgctcttg
      841 gacatcgagc ggtcctctca ggggatctca agcggtatgc ggacatggcg gcagcgcgcc
      901 ggcgcgcgga cgcgcgcggc gggcggtgcc ggtggcctta cggccggtcc gtcacagccg
      961 gagaacctgg agggacgcca gggagatggg ggagaggacc ccgccgggcg gcggcgcggg
     1021 cgcccgggga gcgcgggccg gcaggcgcag cagcgcccgg cggcccgtgg cgagccccag
     1081 cagcatgagg gcgaagagca ccgccaggca gaggcacgcg tcggccgggg ccagcggcgg
     1141 gagcctcagg ggcgcgctga gggacgcggc ggcggtcccg gcgtggccgg gcacgccgtg
     1201 gacggccgcg ggatgggcgg cggggccgcc gggggacgtc gaggcgtggt gcatcgcggt
     1261 ggcgacctcg gcgggcacgc tcatcccgtt ctcgatgcac acgcggtcgg gcagggcgtg
     1321 cccgaggccg tagctgaaga cgagcccggc cacgacgaac agcgccacga gcaggcccgc
     1381 ctgcccatgg cgccggcggt gggccgttcc ggacaccgtc acgctcctga ttccgtcttc
     1441 cggccggtaa caacgcggcg gcggggcccg gggttcccgg ccccgtctcg gactccgggg
     1501 ggaggccgat accctcctga cggatcaggc gtgccgcgcc gggtggctgg aggatgaacc
     1561 ctatgcggcg ttcagggggt acggaggcca ttctgcgacg tgaactgacc ggccgccgcc
     1621 tcgtcgcggc gaccgcggta caagtgctgg tgatgggcgt ggtgatcggg gcctacgagc
     1681 tcggccgcca tttcgccgac ggacgtccgg gcgacgcgtt cgcgcacgcc cggtggctgt
     1741 gggacctgga gcgcacgctc cgcctaccgg acgagtcggc gttccagaag tgggcgctcg
     1801 gctgggacgg ctgggtccgc gcggcgaacg agtactacgt ccgcgtgcac ttcccggcga
     1861 tcctgctgtt catggcctgg atgtggttcc ggcaccggga gggctggccg cgggtccgcg
     1921 ccgtgatcgc gatcacggcg gccgccgcgc tggcgctgca cttcgcgttc ccgctggcgc
     1981 cgccgcgaat gctgcccggc cacgggttca tcgacctcat gaacgtgtac ggcccgagct
     2041 cctacagctc gaagccgggg gaggggatgg ccaaccagtt cgcggccatg ccgtcgctgc
     2101 acgtcggatg ggcgctgctg gtcgcctggg gcgcgatccg ctacggcggg ggccgcctgc
     2161 gctacatcat ggccctccac cccgtgctga cgttcctcat cgtggtcgtc accgccaacc
     2221 actactggac ggacgggatc gtcggctgca cgatcgtcat cgtgacgctg tgggcgacgt
     2281 ccaaggtccc ggcgctggcg gaccggacgc ccgagcgggc aggagtgtcg ctgccgcgag
     2341 atagtgtcgg agcgtgacga gcagggcgga accgggccag tcggaggggc tcttcgacga
     2401 tccgtcggcc gaggcggaga gcgcctccgc cgagcgtgag cgcagcgcgc ccgcgagggc
     2461 ggcggaggcc gggcggcagc cgctcgcggt ccggatgcgg ccgcgcgcgc tggacgaggt
     2521 cgtcgggcag gggcatctcc tcggccccgg aaccccgatc cggcagctcg tcgaccggga
     2581 cgtcccgatg tcgctggtcc tgtggggccc gcccggcacc ggcaagacca ccctcgccac
     2641 ggtcgtcagc cacgtcacgt cccgccggtt cgtggagatc tccgcggtca gcgacggggt
     2701 caagcgggtc cgcgccgaga tcgacctggc ccgccgcgag ctcggcatga cggggcggca
     2761 gacggtcctg ttcgtcgacg aggtgcaccg cttcaacaag gcccagcagg acgcgctgct
     2821 ccccgcggtc gagaaccggt gggtgtcgtt catcggcgcc accaccgaga acccgttctt
     2881 ctccgtgatc agcccgctgc tgtcgcggtc gcttctgctc actctcgagc cgctcggcga
     2941 cgacgacctg cgcgaggtga tccgccgcgc gctcgccgac gagcgcggcc tgaacggcac
     3001 ggtcggcctc gaccccgccg ccgagaacca cctgatcagg ctcgccggcg gcgacgcccg
     3061 ccgcaccctc acctacctgg aggccgcggc gctcgtcgtc gacgagggcg cggtgatcga
     3121 cgcggacgtc ctggagaagg ccgtcgaccg cgccgccgtc cgctacgacc gcgagggcga
     3181 ccagcactac gacgtcatca gcgcgttcat caagagcatc cgcggcagcg acgtcgacgc
     3241 cgcgctgcac tacctcgccc gcatgatcga ggccggcgag gacgcccggt tcatcgcgcg
     3301 ccgcctcatc gtgcacgcca gcgaggacgt cggcatggcc gacccgaccg cgctgcagac
     3361 ggccgtcgcg gcggcgcagg cggtcgagtt cgtcgggctg cccgaggccc gcatcaacct
     3421 cgcgcaggcg gtgatccacc tgtccctcgc gcccaagtcc aacgcggtga tcagggcggt
     3481 ggacggcgcg ctcggcgacg tccgcaaggg cctggccggg cccgtccccg ggcacctgcg
     3541 cgacgcccac tacaagggcg ccgcgaagat cgggcacggc aagggctaca agtacgccca
     3601 cgaccatccc ggcggggtcg tccggcagca gtacgcgccc gacgcggtgg acggccgcga
     3661 gtactacagc ccgacccggc acggcgcgga gtcccgcttc accgaggtcc tcgcgcgcat
     3721 ccgctcggtg ctgcgcggag cgccgggccg gtgagccgga ccatgaagat cgatcttccc
     3781 ggcgccgtgc tccgggcatc ggcgccgcgg ggccgctact ctgccgggaa cggccccggg
     3841 cgcggtcccg gcgcgccggc cgcccggccg gcgcccgccg ccgcccggcc gtgaccggcg
     3901 cccacggcgc acgtccgggc cggtaaggtc tgtcaggcca atgcccggcc cgggccggaa
     3961 ccacagcgaa cggaagccct catgctcact ggtggacagc tagcaggtct catcgtggcc
     4021 gtgttctggg ctgtgctggt cgcgttcgtc gcgctcacgc tgctgcgcct cgcccgcctg
     4081 ctcggggagg ccagcaagct cgtccgcgac ctcggcgacc aggcggcccc gctgctggac
     4141 gatatgacga cgacggtgaa gcgggccaac gagcagctcg gccgcacgga cgtcatcacc
     4201 aagcaggtcg cgggcgtcac gcagaacgtc tcggccgtca ccaccgtgat gacctcggtg
     4261 gtcggcgggc cgctggtgaa ggcggccgcc ttctcctacg gggtgcgcaa ggccctgagc
     4321 agccgcgacg gggacgggcg gggcgccgcg tccgggcgtc cgcagcttca ggcccgctcc
     4381 tcggggaagg ggcgcaggtg aaacggctct tctggctgtc ggtcggcgcg ggcgcgggcg
     4441 tctacgccac gcaccgcgtc aagcgccggg tcgagcggtt cgcgcgcagc tggtccccgg
     4501 agggggtcgc ggcgcgggcg gtgtcgtccg gccagtccgc gggcgagcgg atgaggcttt
     4561 tcgcggcgga cgtgcgtacc gggatgcagg cccgcgagga ggagctgcgc gaggccgtcc
     4621 ggatggacca ggctccgccc gagtcccccg gggcccggcc ccgccgggtg ctgcgggcgc
     4681 gttacacgat catcgacgac gagaaggatg gccactgatc atggagtcgg cagaggtggc
     4741 gcgccgcttc ctcaagttct tcgaggagcg cgggcacacg gtggtgccct ccgccagcct
     4801 ggtcgccgag gacccgaccc tgctgctggt gaacgccggc atggtcccgt tcaagccgta
     4861 cttcctcggc cagcgcaccc cgccgtcgca gcggatgacc agtgcgcaga agtgcgtccg
     4921 gacgcccgac atcgacgagg tcggcaagac cacccggcac gccacgttct tccagatgct
     4981 gggcaacttc tccatcgggg actacttcaa ggagcaggcg atcccgttcg cctgggagct
     5041 gctgacccgc tcccgcgagg acggcggctt cgggttcccc gaggacaggc tctgggtcac
     5101 cgtcttccac gacgacgacg aggcccgcga cctgtggcac aacaaggtcg gcgtccccct
     5161 cgagcgcatc cagaagcgcg gcatggagga caacttctgg tcgatgggcg tccccggccc
     5221 ctgcggcccc tgctcggaga tctactacga ccgcggcccc gagtacgggc gcgagggcgg
     5281 cccggtcgcc gacgaggacc gctacctcga ggtgtggaac ctcgtcttca tgcagttcga
     5341 gcggggcccc ggcgacagca agaccgactt cccgatcctc ggcgacctgc ccgccaagaa
     5401 catcgacacc ggcatgggcc tggagcgcat ggcggcggtc ctgcagggcg tcgacaacat
     5461 ctacgagacc gacaccctgt ggcgggtcct ggaccgcgcc gcgaacctga ccggcacgtc
     5521 ctacgggcgc gagcaccgcg ccgacgtgtc gctgcgcgtc atcgccgacc acgtccgcag
     5581 cgggacgatg atggtcgccg acggcatccg ccccggcaac gagggtcgcg gctacgtgct
     5641 gcgccgcatc ctgcgccgct cgatccgcaa cctgcggctg ctcggcggcc aggaggccgg
     5701 gctgatgcac gagctgacct ccgtcgcgat cgccgcgatg ggcgagcagt acccggagct
     5761 gatccgcacc gccgccaaca tccacacggt gatcgacgcg gaggaggagt cgttcctcca
     5821 gacgctgcgc accggcaccg cgatcttcga caccgcggtg gcggagaccc ggcgctcggg
     5881 cggcgggacc ctggccggcg accaggcgtt caagctgcac gacacctacg gcttcccgat
     5941 cgacctgacg ctcgagatgg cctccgaggc cggcctccag gtcgacgagg acggcttccg
     6001 ccggctgatg aaggagcagc gcgaccgcgc caagcaggac gcgcgcgaca agaagaccgg
     6061 caacctcgac gtctccgtcc tcgacgagct gctcaccggc gccggcggca aggtcgactt
     6121 catcggctac cacgacgtca ccgccgacgc gcgcctcgtc gggctgctcg tcaacggcgc
     6181 caacgcgccc gcggcgggcg agggcaccga ggtcgaggtc gtcctcgacc gcaccccgtt
     6241 ctacgccgag ggcggcggcc agctcgccga ccagggcgtg atccggctcg gcaacggcgc
     6301 ggtcatcgac gtgcacgacg tgcagtcgcc gctcgcgggg ctgatcgtgc accgcggccg
     6361 ggtccgcagc ggcgaggcgc aggccggcga ctccgcgcac gccgagatcg acctgacccg
     6421 gcgcgccgcg atctcccggt cgcacaccgc gacccacctc gtgcacgccg ggttccggcg
     6481 ggcgctcggc gagtccgcgg cgcaggcggg ctcggagaac tcgcccggcc ggttccggtt
     6541 cgacttcacc gcctccggcg ccgtcccggc gagcgtcctg cgcgacgtcg aggacgaggt
     6601 caacgaggtc ctcgtcggcg acctggacgt gcgggcgttc cacacctcga tcgacgaggc
     6661 ccgcgccatg ggcgccctcg cgctgttcgg cgagaagtac ggcgacgagg tccgcgtcgt
     6721 cgaggtcggc gactactccc gcgagctgtg cggcggcacg cacgtcgccc ggtccgggca
     6781 gctcggcctg gtcaaggtgc tgggcgagtc gtcgatcggc gcgggcgtgc gccgcgtcga
     6841 ggcgctcgtc ggcatcgacg cgttccggtt cctggcccgc gagagcgtgc tggtcgcgca
     6901 gctcgccgag cagatgaagg cgcgcaagga ggagctgccc gagcgcatct ccggcgtcgt
     6961 cggccgcctc cgcgaggcgg agaaggagct ggagaagctg cgctcgcagc agatcctcgc
     7021 ggtcgccggg tccctcgccg acggcgcgaa ggacgtgaac ggcaccgcgt tcgtggggca
     7081 ccgcgccccc gacggcaccg gcgccgacga cctgcgcaag ctggccgtgg acgtgcgggg
     7141 ccggctgcag gcgcggcccg cggtcgtcat ggtcacgggc gtcccgaagg accgtcccgt
     7201 cgtggtcgtc gccgtcaccc agggcgcgcg ggaccgcggc ctgaaggccg gcgcgctcgt
     7261 cggcctggcc gccaggaccc tcggcggcgg gggcggcggc aaggacgacc tcgcgcaggg
     7321 cggcggcgcg aaccccgccg cgatcgacga cgcgctcgcc gcggtcgaac gagccgtagg
     7381 ggccgcgtga gccccgcggg cgggttaggg gcggcgccat gaggtccgtg aaggacgcgg
     7441 cgcccacccc ggggcgcccc gcgccgcgcg gcggagcgga gcgatgaggc agggcgtgcg
     7501 gctcggcgtg gacgtgggga gcgtccgcgt cggcgtcgca cggtgcgatc ccggcgggat
     7561 cctcgcctcc cccctggaga ccgtgaagag cggcaggggc gacatcgacc ggctcgtcga
     7621 gctggtggcc gagcacgagg cgatcgaggt cgtcgtcggg ctgccgacct cgctgtcggg
     7681 ccgggagggc ccggcggcgc agtcggcgcg caagttcgcc gcgcggctcg cggaccgcct
     7741 tcccccggag gcggtccggc tgtacgacga gcggctcacc accgtcacgg ccgagagcgg
     7801 gctgcgggcg gggggagtgc gcggtcaggc ccgccgcaag gtcgtcgacc aggccgccgc
     7861 ggccgtcctg cttcaagccg ccctggacgg ggaacggttg accgggcgcc ccccaggcga
     7921 gatcgtccgg gggagctcat gaacgatttg gaccttttct ccgatccgta cggtgatccg
     7981 tacgacgagg ggcagccgca ggagccgccg agccggcggg accggcggcg ggcccgcaag
     8041 cgccagcggc gccgccgccg cagcggccgc gcggcgttcc tgttcgcgct ggcgttcatc
     8101 gtcgcggtgt tcggcaccgc gggcgtgttc ggcgccgcga tcctggacaa ccggctgcac
     8161 ccgccggact actccggttc cggcagcggc aatgtcacgg tccaggtgaa ggacggcgcg
     8221 agcggcgcgg tgatcggggc gacgctccag gagcaccacg tggtgaagag cacccgggcg
     8281 ttcgtgaagg tctacaacgg cgagtcgcgc gcctccagca tccagccggg cttctaccag
     8341 atgcgccggg agatgtcgtc gaaggcggcg atggcgctgc tgctggaccc gaagtcgagg
     8401 gccggcaacc agatcacgat ccccgagggc aagcgcgcga tcgagatctt cgagctgctg
     8461 tcgaagaaga ccggcatccc ggtaagggac ttccaggcgg tcgcgaagaa caccaagggc
     8521 ctcgggctgc cgtcgtactc gggcggcaag ctggagggct tcctgtaccc gggccgctac
     8581 gacctcgacc cgaacgggtc ggcgcgcaag atcgtccagc agatggtcga cgcgttcaac
     8641 aaggaggcga gcagctccga cctggagaac aaggcgaaga aggcgggcct cagcccgctg
     8701 cggctgctga cggtcgccag cctcgcgcag gcggagggcg gcaagccgag cgacctgccg
     8761 aagatctccc gggtgatcta caaccgggtc aagtcgggga tggcgctcca gttcgacacc
     8821 accgtcctgt acgcgctgaa caagcggacg ctggacgtgc ggaacaagga cctcgaggtc
     8881 gattcgccgt acaacaccta caagcacaag ggcctgccgc ccgggccgat ctgcaacccc
     8941 ggcccggacg cgatcgaggc ggcgctgtcg ccgaagagcg gggagtggct gtacttcgtc
     9001 gccaccgacc ccacgcacaa gatcacggag ttcgcggtca cggacgccca gcgccagagg
     9061 ctggagcaga agttccggga ctggcaggcg aagcacccgg ggaactgacg ggcgatggag
     9121 cggagcggac ggatggaggc cggggagacc ggcgggacgc ggcgcgccgc cgtgctgggg
     9181 tcgccgatcg cgcattcgct gtcgccggtg ctgcaccggg cggcgtacgc ggcgatgggc
     9241 ctggacgggt ggcgttacgg cgccgtggag tgcggcgagg acggcctggc cccgctgctg
     9301 gacggcctcg gccccgaatg ggcggggctg tcgctgacga tgccgctcaa gcgggtcgcg
     9361 ctgaagctgg ccgactcggt gtcggacctg gccggacggg tcggcggcgc caacacgctc
     9421 gtcctgcgcg acgggcgccg gcacgccgac aacaccgatg tgcacggcat cgtcaccgcg
     9481 ctcaccgagg cgggcctcgg ctcgcccggc tccgcggtgg tgctgggcgg cggcgcgacg
     9541 gccgcgtcgg cgctcgccgc gctcgccgaa ctgggcctgg acgcggcggt cctcgcggtg
     9601 cgcgaccccg gccgggcctc cgaggcggcc gaggtcggcg agcgctgcgg gctgtcggtg
     9661 cgggtcgcca ccctcgaccg ggtcgccgac cacctgcccg ccgggctcgt ggtgtcgacc
     9721 ctgccgggcc gcgccgccga cgccttcgcc gggccggtcg ccgcgtccgg cgccgcgctg
     9781 ttcgacgtgg tgtacgcgcc gtggccgacg gcgctcgccg cggccgtcga gcgcgcgggc
     9841 ggcacggtcg tcggcggctt cgcgatgctg ctgcaccagg ccgtccggca ggtcgagctg
     9901 atgaccggcc gcgacgacgt cccggtcgcg gcgatgcgcg cggccggcga ggcggaactg
     9961 gcccgccgcg ccgccgcccc cgccggctga gaacgggcgg ctagggcgcc gccgggggcg
    10021 ggccgcgcgg cgtccgccgc cgcttgagcg actcgtccac gctcgccagc acgatcggca
    10081 cgatcacgct cagccagaag tcgcgccacc cccacgcgcc gagcttgacg ccgaacgcgc
    10141 tggacacgca cacgaagccg agcaccagcg ccggccagtg ccgccgtgcg aacgccaccg
    10201 ggtcggcgag ccggcggtgc ggcagcagcg ccgccaccgg ccgctcgcgc gcgtgggcgc
    10261 gctgcacgac cgtcgcgtcc gggaaccagt gcagcacgtc cgcgccgccg gcgagcggca
    10321 cgcgggtgag cgcgatcagc gtctccagcc gccaccacag cgtccacagc gaggtgcggc
    10381 cgccgcccgg cgggccgttg cggcgcggat cggcgacctc gccgcgcacc agcgtccgga
    10441 aggcgcgggc gatcgtcggc ccgtgcgggc cgcgcgggtc gtgcagcagc gccgtcagcg
    10501 cgatcggcag gccgtagtgc cacagcgcca gccgccacac cggccgcgac ccgaggccgt
    10561 gcggggacac ctcgtacgtc tcgatccagg tgtggtcgtc gtcggggtcg aggtgggcga
    10621 gcagccagtc gtaggcgtcc agcagccgct cggaccgcag ccccggccgc gcctccgcca
    10681 gcgtcaccag cacgaacgcc gtgtgcgtga cggtcgccgc ggccgccggc accgggcccc
    10741 acgcgggccg gtgcgccgtc cggcccgcgg tcagccactc cacgccccgg tccaccgccg
    10801 ggtcgtacgg gttgagctgc gcgagcgcgc gcagcgccag gcacgtctgc cacacccggg
    10861 acgcgcagcc gtacagcgag ccccagccgc cgtcggggtt ctggttgcgc agcagccacc
    10921 ggtaggcgcg ccgcaggtcc ggggcgtcct cgcgcaggtc gcagcgggcg cgggcgagga
    10981 accgggcgat ccagccggtg gcctccacca cgggcatgcc gaggctcgtg cgggtcgccc
    11041 agccgccgtc gcgcagcgcg tcggcggatg tggcctgtcg ttccgcgagg aaggccagcc
    11101 ccgcgtcgaa gtgctcgaac gggcggcccg cctccacgaa cgccagcagc ccgagcgtcg
    11161 tcgcggtcgt cccgggctcg ggccgggcca gctcgtggta ccagccgccg ccgctgccgg
    11221 gcgcgggcgc gtaggtgtcg cgcaggacgt cgagggactc gtccaagcgg gcctggagca
    11281 ccgccatgtc gatggcgggg gcggcgcggg cgccggagga cgcgggagcg agaggagcgg
    11341 cgcggggcgc gggggcgggg ggctgtgggg gctgtggggt ctgattcacg gttgctgcct
    11401 tctatcccat atgtgcccct tcagccatgc tttgtacccc atgggtcccg tgtctgtatc
    11461 cgtcgccgta cagatcgccg gtgcggcgcc gcgggcacgc tggaggcgac cgcccgtgcg
    11521 tccccgtgtg ctggaggagg cgttggccga gccatcggcg cagcccggcc gcgagtgcgt
    11581 gctgtgcccg cccctccggt tccggatcaa cgccatggcc ggcctgccgg gcgatccgtc
    11641 cgtcctggcc cgggaccgcg acttcctgct gatgcccgac gtcgcgccgc tcgccgacgg
    11701 gcacgtcctc ctcgtcacgc gggagcacca ccagtgcgcg ggcgacttcg acgcacggct
    11761 gtggggccgc gccctccgct ggcgcgaccg cgtctcccgc ctctaccggt acgcctacgg
    11821 caccggcgaa ctgctgctct tcgagcacgg gcctgcgctg tcacagggcg gtggcgcatg
    11881 catcgaccac gcgcactggc acttcctccc cgggacgccg ggcgtccgcg acgtggtgga
    11941 ggagtgcggc ctgccgggta cgcccgccga gttcgcggcg ctccgggccc gcttccgcac
    12001 cgggcgctcc tacctgctgg tcgaggagcg ggggacggcg accgtccatc ccggtgacgg
    12061 cgtgcgcggc cagttcctgc gctgggccgt caccgcggcc ctggggagcg ccgaaccgtg
    12121 gcgctggcag gagacgttcg ggctgcccgg gagccggcgg tgcttcctgc gcaccctgcg
    12181 gacgctgcgg cgcgcggccg ccgccctcga cggcccgcct ccgtgcgagc accggtagga
    12241 cggccaccgc taggacggac ggccgtcagc gggcggccgg caggaacgcc cgcaccaccg
    12301 ggcgcaggct cgggatcagc gggtaggacc acacctcgcc cagcggcacc caggcgcatc
    12361 cgtccaggtg gtcgctctcg tcctggttgc cgaaccggac gtcgagcgtc agcgggcggc
    12421 agcggcgggc cgccgcgacc acccggaccg tcccgcctcc cgcgcccggc gaccggtcgt
    12481 ccatgaacca ctgccacagg tggaacggcg gccccggatc gatcttcagg ccgacctcct
    12541 cccacacctc ccgccggatg tggtcgtcga ggtccaggtc tccgccgacg tccagccgcc
    12601 cgccgggcac ctcccagcgg ccgggctgga aggggtcgga caccgccttg cgcaccatca
    12661 ggagccgccc cgcggaggtg atgaacgcct tctgcgcgaa ctgcaggcgg acgggcggcg
    12721 aggcggtggc ggggccgggg gagccggtct ctggtgaggg catcgcggga atacctccct
    12781 ggcaccggcc caccggggcc gacctggcat cacggtaaca aggcgggctt ccgggccggg
    12841 gtgttcggcg ggccagatga ccgtcacttt cccaggtcga agacggccgg ccggggctcg
    12901 gtgacgcggc cgtacgcggc gcccgccccg catgcgggaa tgcggaggcg cccggccggg
    12961 ttggaacgat cggcgtatcc cgcggcggac gcggaaccag cggggcgcgc acacgccccg
    13021 caggtggtag tgttagtggc cgaccggccc tgtgcacgcg accgatgagg tcgtgcgcgc
    13081 cgggcgctca agcggaggcc acctcccacc tgaccggccg agaggccggt gggtatcggt
    13141 ccggcgaacg ggcgcggcgc gctcgttccg ccgtcgtccc cggacggcag tagccgttca
    13201 gggcgaccga aggtggcccc gcacgtgagt cgtgcggggc ttttcgcgtg agagcctcgg
    13261 ggtacgaccg gtcccagaac ttgagaacgg ccccaaggag gtcccatcag cgccgaaccg
    13321 cgtatcaacg accgcattcg cgtgcccgag gtccggctcg tcggcccgaa cggcgaacag
    13381 gtgggcatcg tgcccatcgc caaggccctt gaactcgcgc gtgagtcgga cctcgacctg
    13441 gtcgaggtgg cgcccaccgc gcgcccgccc gtcgccaagc tcatggacta cggcaagttc
    13501 aagtacgagt ccgcgatgaa ggcgcgtgag gcgcggaaga accaggcgca cacgatcatc
    13561 aaggagatca agctccgccc gaagatcgac ccgcacgact acgagaccaa gaagggtcac
    13621 gtggtgcggt tcctgaaggc cggggacaag gtgaaggtca cgatcatgtt ccgtggtcgt
    13681 gagcagtccc gtcccgagct cggtttccgg ctgctgcagc ggctcgccga cgacgtcgag
    13741 gagctcggct tcgtcgagtc gcggcccaag caggacggcc gtaacatgat catggtgctc
    13801 ggtccgcaca agaagaaggc ggaggccaag gccgagcggg ccgcgagccg cgagcaggac
    13861 gcggcgaccg gaccggcctg acccgccgcc cgacgcgcga gcgcgacgcc ggccgcgaag
    13921 gcggccgcgg cgcccggtcg tgaacgcccg accgcggcgc caggcccggc gctgcccgcg
    13981 cgagcgcgga gcgcaccggg cgcagtgcac gcacgatctg gtgccggacc ggccgcgacg
    14041 ccggtccggc cgcaacgccc gcggcccgca agggccgccg ggccccccgc cccgggcggc
    14101 gggcccgccg gcggtctcgt ggctttcgcg gggccgttac gcacgtacat tgaagcctga
    14161 cctggcgcgt cgcacgcgtc cgagtgcgac gcgccgatca ggtgcgctcc cgtgccgccg
    14221 cacgggggcc gggaacgagg gagacgacgg cgaccatgcc gaagaccaag acccacagcg
    14281 gtgccaagaa gcgcttcaag ctgaccggct ccggcaaggt gatgcgccgc cgcgccaaca
    14341 agaaccacct gctcgagcac aagcccacca agcggacgcg ccgcctgtcc ggccccgccg
    14401 tggtggccga cgccgacgcc aagaacatca agaagctgct gcgcaagtag caccgaccgg
    14461 caacatcgac gaccggccgg cgccaggacg gctccggccc ccacgaagga gttcagcacg
    14521 tggcacgcgt gaagcgggcg gtcaacgccg ccaagaagcg tcgggtcgtt ctggagcggt
    14581 cgagcggcta ccgcggccag cgttcgcggc tgtaccgcaa ggccaaggag cagcagctcc
    14641 actcgatgac ctacgccttc cgggaccgca aggaccgcaa gggccagttc cgccgcctgt
    14701 ggatccagcg gatcaacgcc gcggcccgcg ccaacggcat cacctacaac cggttcatcc
    14761 agggcctgaa ggccgccgag gtggaggtcg accggcgcat gctggccgag ctcgccgtga
    14821 acgacgcccc cgcgttcgcc gccctggtca aggtggccaa ggacgcgctg ccggcggagg
    14881 ccgcctgagc cgggcgacct ggcgacgggc gagtacggcg acatggcggg ccgcgagctg
    14941 acctctatcc gatcaccacg ggtgaaggcc gctcggcggc tcgccaaacg cgccttccgg
    15001 cgccgtgagg ggcggttcct cgccgagggg ccgcaggcgg tgcgggaggc gctggagatc
    15061 cccggcgggc tggccgagct gttcaccacg gccgaggccg aggcccgcca tcccgagctg
    15121 gtggccgccg ccgagcgcgc cggggtcccg gtgctgcggg tcagcggcga gatcatggcg
    15181 gagctggcgc agaccgtgac cccgcagggg ctgctggcgg tctgcgggtt cgtggacgtc
    15241 ccgctggccg gcgcgctgga gtccggcccg cggctggtga cggtcctcgc gcacgtccgc
    15301 gaccccggca acgccgggac ggtgctgcgc accgccgacg cggcgggctc ggagacggtc
    15361 gtgttcaccg acgcgtccgt cgacccctac aacggcaagt gcgtgcgcgc ctcggcgggc
    15421 agcctgttcc acctgccggt ggtggtcggg ccgcgtttcg acacgctgat cccggagctg
    15481 aagaagtcgg ggctgacggt gctggccgcc gacggcgccg gcgaccggac cctggacgag
    15541 gccatcgacc aggggctgct ggcgcggccc accgcctggg tgttcggcaa cgaggcgtgg
    15601 gggctgcccg aggagatcct ccggcacgtg gacgaggtgg tccgggtgcc gatctacggc
    15661 cgggccgaga gcctgaacct ggcgacggca gcggccgtct gcctgtacgc ctcggcgcgg
    15721 gcgcagcgcc gggcctgaga cgcgccggcc ccctgaggga gcgcgcgcgg acacgtacga
    15781 gcacccgcgg cggttcaatg cgttccgtgg ccggttggcc gcaagcggtc gccttcgaag
    15841 ccgtttcgtg ccgggtgagc tgcgaagatg gtcttcccgt ggacggcagg gcagggggcc
    15901 cgccggcacg ggtgactcat tccaaggtag gagcgggata ccggcccggc ggtggatccg
    15961 accgcgccgg cccgctgcct acggtgttga ccagggcgtt gaccagggcg gcagcggtgc
    16021 cgccgcagag tgggggcgaa cgtgatgacc gaggagacca ggccggcgag gcggccgggc
    16081 cggcgcgcac cggagatccg gtgccggacg ggcgccggcc aggccgcgcc gctcggttcc
    16141 gcggcgcccg gcacgaccac ggccggcacg cccgcgcccg gcgcggtcgc gcggggcgac
    16201 ggagcttccg ccgcggtggc gctcgacgcg gccggtgcgt gggcgcccgg cccggtggcg
    16261 ggcctggtgg tcgaggtcgc cgagcggcgg ccggggaccg ccgtcgtcac ggtgaccggc
    16321 gagatcgacc tgcacaccgc ggacggcctg cggtcccggc tggtcaaggc gcacgccgcg
    16381 ggggcgcgcc agctggtgct ggacttcgcc gccgtcccgt tctgcgacgc ggccggtctc
    16441 ggcgcgctcg tcggcgcgca caacgagatc tccccgtccg gcggcgagat cgtgctggcc
    16501 ggcgtgcggc ccgcccagct gcggctgctg cgcatcaccg ggctgcaccg gctgttcgcg
    16561 ctgcacgcgg acgtcgaggc cgcgctcgcc ggccaggatt cgcccaccgg ctcccgctga
    16621 gcggacccga tccggcccgc cggtcctgac cccgcggtca ggacgccgcg gcggcaccgg
    16681 tcatgatcgt ttggttgcgt ccggccttgc cggcaccggg cgcggcgaag ccgccggaca
    16741 caccccccgg cggctacaaa tgccttgccg cggggccttc tccgggtccc gtaaggggcc
    16801 cgactgcgga tagagtctct tctcgacagg ccgcgctcta ccggtgttct ggaggccgct
    16861 gtgggcggag aggaaccccc cggcgtggcc gcgcgcgctc tctccgggcc cgagcaggcc
    16921 gacgacctgc cggacgggct gctggtcgcc gaccgcgacg cccgcgtcgt ggtgttcaac
    16981 acagccgccg agcggatgac cgggatcgcc gccgcggccg cgctgggctg cgacttccgc
    17041 gacgtcctgc ccctgcacga cgccgagggc cgcgactggt ggaagtgcct ggcgccctac
    17101 gacggtctgc cgacccgcac ccggcacccc gagcggtcgc tgttcctgcc cggcggcacg
    17161 gagctgctgg tgaccgccgg ctaccggcgc ggcgacggcg gccgggtcga gcggttctcg
    17221 gtctgcatgc gcgacgcgca gcgccgcgcc cgccaggagc gcgaccgcgc cgacctggtc
    17281 tccaccgtcg cgcacgagct gcgctccccg ctgaccagcg tcaagggctt caccgcgacg
    17341 ctgctggcca agtggcaccg cttcaacgac gaccagaagc gcgtcatgct ggagacggtc
    17401 aacgccgacg ccgaccgcgt cacccggctg atcaccgagc tgctggacgt gtcccggatc
    17461 gaggcgggcc ggctggagat gcgccgccag gtcgtcgacc tgcccgacga ggtccgcaag
    17521 gtcatcgcgg gccgggtcgc ggccggcgac gccgaggacc ggttccgctt cgaggtccgc
    17581 ggcgccctgc ccgagatgtg gctcgatccc gacaagatgg accagattct cggcaacctg
    17641 gtggaaaacg cggtgcggca cggcgccggc actgtcacga tcgtggtgga gccggacgcg
    17701 cacaaggagg gggccgccgt gtcggtgcgc gacgagggcg agggcatacc gcccgaagcc
    17761 gtccagcgcg tcttccggca gttctggcgc ggtccgggcg gcaaccgccg cggcggcacc
    17821 gggctcggcc tgtacatcgt gaagggcctg gtcgaggcgc acggcggcgc gatcacggtg
    17881 cggcgggcgc ccggcggcgg cgccgagttc cgatttaccg tgcccgccgg ggcccccgac
    17941 cacgcgagct gagccctccg ggcgcggccc gcggccgcga agggctccgg gcgggccgcg
    18001 cgtcacgcgc acgctttccg gatgtccacc gcccgcgcac tagactgcgg gcgtcccacg
    18061 ccgaccggag tcgatcacac caccatgtct gcacccaaca agtcctatga ccccgtcgag
    18121 gtgtccgcct tgcaacccga gcagctcgat gcggcccgcg acgaggcgct cgcggccatc
    18181 gccgcggccg ccgacctcga cgcactcaag caggttcgcc tggcgcacgc cggcgaccgc
    18241 tccccgctgg ccctcgccaa ccgcgagatc ggcgcgctgc cgccggccgc gcgcgccgac
    18301 gcgggcaagc gcatcggcgc cgcccgcggc gcggtgtcca aggcgctgaa ggagcgccag
    18361 gccgccctgg aggaggagcg cgaccagcgg gtcctcgtcg aggagaccgt cgacgtcacg
    18421 ctgccctggg accgcgcgcc gcgcggcgcg cggcacccgc tgaccaccat gcaggagcgg
    18481 atggccgacg tcttcgtcgc gatgggcttc gaggtctccg agggccccga ggtcgaggcg
    18541 gagtggttca acttcgacgc gctgaacttc ctgcccgacc acccggcccg caccatgcag
    18601 gacaccttct tcgtggagtc ggaggagtcc gggctggtga tgcgcacgca cacctcgccg
    18661 atgcagatca ggtcgctgct gtcgcggccg ctgccggtgt acgtggtcgc gccgggccgc
    18721 acgttccgca ccgacgagct ggacgcgacg cacagcccgg tgttccacca gctggagggc
    18781 ctcgccgtcg acgagggcct gaccatggcg gacctgcgcg gcggcatcga cgcgttcgtc
    18841 accggcatgt tcggcgcggg gctgaagacg cggttccggc cgtcgtactt cccgttcacc
    18901 gagccgtcgg cggaggtgga catgcagtgc ttcgtgtgcc ggggcgcgtc cgcggagccg
    18961 ggcggcgagc cgtgccgcac ctgcggctcg gagggctgga tcgagctggg cggctgcggc
    19021 atggtcaacc cgcgggtgct ggtggcctgc ggcgtcgacg ccgaccgcta cagcggctgg
    19081 gcgttcgggc tgggcgtcga gcggacgctg atgttccggc acggcgtcga ggacatgtac
    19141 gacatggtgg agggcgacgt ccggttcacc ctcccgttcg ggatggagat ctgatgcggg
    19201 ccccgctttc ctgggtgcgc gagcacgtcg agctgccggc cggcgtgacc ggccgggacc
    19261 tggccgcgaa gctgatcgcg gcgggcctgg aggtcgagac ggtcgagcag gccggcgccg
    19321 acatcaccgg cacgctcgtg gtcggcgagg tcctggcgat cgaggagctg accggcttca
    19381 agaagccgat ccgctactgc caggtgaacg tcggcgacgc caacggcacc ggcgagccgc
    19441 agaacatcat ctgcggcgct acgaacttcg aggtcggcga ccgcgtcgtg gtgatcctgc
    19501 ccggcggcgt gctgcccggc ggcttccaga tcggcgcccg caagacctac ggcaggctgt
    19561 ccgagggcat gatctgctcg gtcaccgagc tcggcatcgg cgacgaccac agcggcatcc
    19621 tcgtgctgcc gccggacacg ccggtcggcg ccgacgccgt cgagctgctc ggcatccgcg
    19681 acgacgtcct ggacatcgcc gtcaccccgg accgcagtta cgcgctgtcg atccgcggca
    19741 tcgcccgcga ggccgcgacc gcctacgacg tcccgttcaa ggacccggcg gacgtggagc
    19801 tgcccgccaa gaacggcgag gcgtacccgg cgagcatcgg cgacccgacc gcgtgcgacc
    19861 ggttcgtcct gcgggaggtg cgcggcttcg acccggacgc gcagaccccg atgtggatgc
    19921 aggtgcgcct gcaccgcgcg gggatgcgcc cggtgtcgct ggcggtcgac gtcaccaact
    19981 acctgatgct ggagctcggg cagccgctgc acgcgttcga ccgggccaag ctcaccggcc
    20041 cgatcgtggt gcggcgcgcc gagaagggcg agagcctgga gaccctcgac cacgtcaagc
    20101 gcaagctcga ccccgaggac atcctgatca ccgacgagtc gggcccgatc tcgatggccg
    20161 gcacgatggg cggcctcgcg acggagatcg acgaccggtc cgccgacatg gtcatcgagg
    20221 ccgcgcactt cgacgcgatc ggcaccgccc ggatgagccg ccgccacaag ctgcacagcg
    20281 aggcgtcgta ccggttcgag cgcggcgtcg accgcgagct gccgctgtac gcgtcgtacc
    20341 gcgcggcgcg gatgctggcg gagctgggcg gcgcggagat cacgccgggc gtcacgcacg
    20401 ccgaggcgcc ggtcgccggc gtcgcgatca cgatgccggc cgggcacccc gacaaggtcg
    20461 cgggcgtgac ctacgggcgc gacacggtcg tgcggcggct ggagcaggtc ggctgcgcgg
    20521 tcgagggcgg cgacgtcctc acggtgacgc cgccgtcctg gcggcccgac ctcaccgacc
    20581 cgaacgacct cgccgaggag gtcatccggc tcgagggcta cgaggacatc ccggcccgcg
    20641 cgccgcgccc gtccgccggg cggggcctga cgatccagca gcggctgcgc cgccgggtcg
    20701 gccgcaccct cgcgggcgcc gggtacgtcg aggtgctggc gttcccgttc gtctccgcga
    20761 aggactggga cgacctgcaa ctgcccgccg acgacgcgcg ccgccgcacg ctgcggctgg
    20821 cgaacccgct gtcggaggag gagccgctgc tgcgcaccac gctgctgcca ggcctgctgc
    20881 gcacgctcgc gcacaacgtc gggcggggct tccccgacac ggcgctgttc gagctgggcg
    20941 tggtgttccg gccgcgcccg ggcgcgccgg agcgggcgcc gcgcctcgcg gtggaccgcg
    21001 gcccgacggc cgaggaggtc gcgtccgtcg aggcggcgct gcccgaccag ccgcaccggg
    21061 tggcggtcgt gctgtccggc gaccgcgagc cctcgggctg gtggggcggc ggacgtccgg
    21121 cgctgtgggc ggacgcggtg caggccgcgc gcatggtggc ggccgaggtc ggcgtggagc
    21181 tgacggtgaa ggccgaccag cacgcgccgt ggcatccggg ccgctgcgcc gcgctgtacg
    21241 cgggcgacac gctcgtcggc cacgccggtg agctgcaccc gcgcgtcacc aaggcgtacg
    21301 ggctgccggc gcgcagctgc gcgatggagc tggagctgcg ccgcctcggc gagccggtga
    21361 cggtccgcgc gccgcacgtg tcgacctac
//
