LOCUS       NZ_CP053892            50940 bp    DNA     circular CON 05-MAY-2024
DEFINITION  Actinomadura verrucosospora strain NRRL:B18236 chromosome.
ACCESSION   NZ_CP053892
VERSION     NZ_CP053892.1
KEYWORDS    RefSeq.
SOURCE      Actinomadura verrucosospora
  ORGANISM  Actinomadura verrucosospora
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 10214634)
  AUTHORS   Samborskyy,M.
  TITLE     Actinomadura verrucosospora NRRL-B18236 (PFL_A860) Genome sequencing
            and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10214634)
  AUTHORS   Samborskyy,M., Dickens,S. and Scott,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAY-2020) Biochemistry, DNA Sequencing Facility,
            University of Cambridge, 80 Tennis Court Road, Cambridge,
            Cambridgeshire CB2 1GA, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-DEC-2016
            Assembly Method                   :: Newbler v. 3.0
            Assembly Name                     :: A860_AS2.mpe1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013211575.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 03:37:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,277
            CDSs (total)                      :: 9,181
            Genes (coding)                    :: 9,110
            CDSs (with protein)               :: 9,110
            Genes (RNA)                       :: 96
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 18 of 71
            Pseudo Genes (incomplete)         :: 57 of 71
            Pseudo Genes (internal stop)      :: 2 of 71
            Pseudo Genes (multiple problems)  :: 6 of 71
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:15:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9743574
            Orig. end                         :: 9794514
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP053892.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Peter Leadlay,
            NRRL-B18236 (patent collection, not in online catalogue).
FEATURES             Location/Qualifiers
     region          1..50940
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="NRPS"
                     /product="T1PKS"
                     /region_number="33"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..50940
                     /SMILES="C=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..42721
                     /SMILES="C=CC(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..42721
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:22721](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..22721
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            598..1185
                     /locus_tag="ACTIVE_RS44090"
                     /old_locus_tag="ACTIVE_8835"
     CDS             598..1185
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025343.4"
                     /locus_tag="ACTIVE_RS44090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8835"
                     /product="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="WP_173100508.1"
                     /transl_table=11
                     /translation="MVKVDPERRRADVVEAVWRVVRRDGLSAASVRNVAQEAGLSMGSL
                     RHYFASQAELLSFTLRAVIERIEARIAALPSEPDPRRRAERVLLELLPLDPERAAENEV
                     WLAFTARAQVDPELRAVHDEGYDVLRGGCRRLVEGLAGHVEGLDVELETDRLHALLDGL
                     AVHIAMRPDALTPDRARLIVARHLDELTRYAR"
     misc_feature    complement(1264..1277)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.46"
                     /tool="antismash"
     misc_feature    1265..1278
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.13"
                     /tool="antismash"
     misc_feature    complement(1823..1836)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            1998..2327
                     /locus_tag="ACTIVE_RS44100"
                     /old_locus_tag="ACTIVE_8836"
     CDS             1998..2327
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040072.3"
                     /locus_tag="ACTIVE_RS44100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8836"
                     /product="DUF6355 family natural product biosynthesis
                     protein"
                     /protein_id="WP_173100509.1"
                     /transl_table=11
                     /translation="MTAFSSPAHAEFKRVPEVWQAGADAFAAPPCGFFRYRVRESEFAA
                     YNHCGPTTVRIHVDVRGGGSANDYHLCVSPGRTQLPGAGPNYLNAYYIGGAGCRSGERT
                     GHTPH"
     gene            2438..2602
                     /locus_tag="ACTIVE_RS47965"
     CDS             2438..2602
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS47965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_246343250.1"
                     /transl_table=11
                     /translation="MVERITERILRLAAGRLRVAIDGLTAAGKTSLGANSQSKSALPGA
                     RYSGRRLRF"
     gene            complement(2579..2908)
                     /locus_tag="ACTIVE_RS47970"
     CDS             complement(2579..2908)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /locus_tag="ACTIVE_RS47970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="WYL domain-containing protein"
                     /protein_id="WP_343062992.1"
                     /transl_table=11
                     /translation="MESFGRERAPVDTAEALLTLVRACRDEVGADFDYPSGNEVRRRQV
                     EPYRLVASDRRWCLLAYGLERDDWRCFRVDRMSAVSARTRRFRSRAAPDAEAAGRRYSE
                     AESAP"
     gene            complement(2854..3252)
                     /locus_tag="ACTIVE_RS47975"
                     /old_locus_tag="ACTIVE_8837"
     CDS             complement(2854..3252)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019884.4"
                     /locus_tag="ACTIVE_RS47975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8837"
                     /product="HTH domain-containing protein"
                     /protein_id="WP_246342560.1"
                     /transl_table=11
                     /translation="MLTLVGLQQRREWTGPELADRLGVTARTVRRDVERLRTLGYPVHA
                     TQGVGGGYQLGRGQVLPPLLLNDEEAIATAVSLLVSAVASASDAALRALAKLDRVLPTR
                     LRDEVRPPPARWSPLAESVRRSTPPRRC"
     misc_feature    3275..3290
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            complement(3407..4282)
                     /locus_tag="ACTIVE_RS47980"
                     /old_locus_tag="ACTIVE_8838"
     CDS             complement(3407..4282)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="ACTIVE_RS47980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8838"
                     /product="MFS transporter"
                     /protein_id="WP_246342561.1"
                     /transl_table=11
                     /translation="MVAIIAALRLLAESRGVGTRGPDLIGAITVTLGLPALEFGMLQTP
                     AYGWGSARALILMGVGVLALAAFVLVEATFARAPLMPLKVFRARSVSGALLVQFLLGVA
                     GFAVWYFLSLYMQQVLHYSALQAGLAFLPHTLAIIVTSKATPRLLGRAGLRPLLAAGTL
                     ISAVGFAWQATITPDSGLLTGIVLPGVLITGGMGLTSAPIAMAATAGADPGEAGLISGI
                     LNSSRQVGGSLGLAALTTLAAARTGAPTSGYAMAFWACAGVVAAGALAVLALPKTQRDV
                     PDARERHQGM"
     gene            complement(4300..4845)
                     /locus_tag="ACTIVE_RS47985"
                     /old_locus_tag="ACTIVE_8839"
     CDS             complement(4300..4845)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="ACTIVE_RS47985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8839"
                     /product="MFS transporter"
                     /protein_id="WP_246342562.1"
                     /transl_table=11
                     /translation="MMNVADAPPSGRSIARPPSPVWPIVGLVCLAQFMMVLDVSIVNVA
                     LPAMESGLHLGAERLQWVVNGYVLTFAGFLLLGGRAADLFGRRRTFVAGLAVFAIAGLA
                     GGLATTPELLIAARASQGLGAAVVAPATLTILTTAIPTETARARAIATWGAVGATGGAV
                     GSLAGGCSPTTCRGVGSC"
     misc_feature    4844..4860
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.4"
                     /tool="antismash"
     gene            complement(5121..5510)
                     /locus_tag="ACTIVE_RS44115"
                     /old_locus_tag="ACTIVE_8840"
     CDS             complement(5121..5510)
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013228.4"
                     /locus_tag="ACTIVE_RS44115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8840"
                     /product="RidA family protein"
                     /protein_id="WP_173100510.1"
                     /transl_table=11
                     /translation="MGVRHINPEGLHRSPAFSQAVVVEQPAKTIYVGGQNGVGADGKVV
                     GPSVGDQARQAFRNLETILKSEGASLANIVHWRIAVVDGHSFDEGVAAFQEVWNRADPP
                     PAITVHVVAGLGPGFLVEIDAVAVV"
     cand_cluster    5445..50940
                     /SMILES="C=CC(=O)O"
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    5445..50940
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[25444:30940](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      25445..30940
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     gene            5578..6180
                     /locus_tag="ACTIVE_RS44120"
                     /old_locus_tag="ACTIVE_8841"
     CDS             5578..6180
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017599351.1"
                     /locus_tag="ACTIVE_RS44120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8841"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_246342563.1"
                     /transl_table=11
                     /translation="MRANATGRVLHDPKGGSFRFDAGAVCLDFAHTGGEGRYAIFESLH
                     EPADLAEWLAQPPLAVAMTAAVTARELTAAKALRQAIWDAAHARASGRPLPASAIATIN
                     RAAIAAPLIPELAADGTTAGWAPPVRATQALSTLAREMIELLAGPLAERIRECAGDNCP
                     LVFVDTSRPGARRWCAMERCGNRHKLRALRARQAMEP"
     misc_feature    7095..7109
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.65"
                     /tool="antismash"
     gene            7175..>7658
                     /locus_tag="ACTIVE_RS44125"
                     /pseudo=""
     CDS             7175..>7658
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017565183.1"
                     /locus_tag="ACTIVE_RS44125"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="glyoxalase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTVPLMPCASVEDALAFYEALGFEATYKQSRPYVYLALQWSGFQL
                     HFGPAPKGLDPAREESGGCLVMVDAVAPYHAEFVAAMLPGVREGAEDRPTANHPLPARR
                     VPVHADRSVRKLDHLHPARRAG"
     gene            complement(7975..9519)
                     /locus_tag="ACTIVE_RS44130"
                     /old_locus_tag="ACTIVE_8843"
     CDS             complement(7975..9519)
                     /EC_number="1.4.-.-"
                     /GO_function="GO:0015930 - glutamate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016638 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors [Evidence IEA]"
                     /GO_process="GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013784.4"
                     /locus_tag="ACTIVE_RS44130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8843"
                     /product="FMN-binding glutamate synthase family protein"
                     /protein_id="WP_173100511.1"
                     /transl_table=11
                     /translation="MRARSIGAAAATALALVAARDLIQKKHALLRNFPVVGHARYLLET
                     IGPELRQYIVTSNEEERPFSRDQRAWIYASAKEENNYFGFGTETDVEHVQGHAYVKQRT
                     FAGTLPDVHDPQAPLPSAKVLGGPRGRAKAFRPASVVNISAMSFGSLSGAAITALNQGA
                     ALAGTMHNTGEGGLSPYHRNGGDLVLQLGTSYFGCRDEDGGFNLGKLKDVVAGAPVKAI
                     EIKLSQGAKPGLGGMLPGAKVTEEIAEIRGIPAGKDCASPSRHTAFSDVDSMLDFVELL
                     ATETGLPVGVKSAVGEMAFWQELATLMARGDRGVDFVTIDGGEGGTGAAPRIFADSVAL
                     PFRMGFSRVYGTFAELGLTDEVTFIGSGKLGLPENATVAFALGADMVNVAREAMLSIGC
                     IQSQKCHTDRCPTGIATQNPWLARGIDPTSKATRAAVYLRTLRRELIKVSSAVGVAHPA
                     LITANDIEIMNGDYEARTLASVYDYKDGWGELGPHLADEITALITTTPASAQEPIV"
     misc_feature    complement(9849..9862)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.68"
                     /tool="antismash"
     gene            complement(10237..10806)
                     /locus_tag="ACTIVE_RS44135"
                     /old_locus_tag="ACTIVE_8844"
     CDS             complement(10237..10806)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03083.1"
                     /locus_tag="ACTIVE_RS44135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8844"
                     /product="TIGR03086 family metal-binding protein"
                     /protein_id="WP_173100512.1"
                     /transl_table=11
                     /translation="MSHLSNAAEAMAAVARAITDDQLANKTPCTEYDVRALVNHLLFWG
                     PSLAGGGRKESVPQPAGAESDVDLATGDWRGRLLALLDDITSSWAPPSAWEGETSMGTP
                     HSLPAPVLGDMITGELALHGWDLAVATGQRLELPADLLEHLHDTVLAGVEQGREMGMYG
                     PEVAVPADAPTLDRILGLTGRDPAWT"
     misc_feature    complement(10800..10810)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            10871..11614
                     /locus_tag="ACTIVE_RS44140"
                     /old_locus_tag="ACTIVE_8845"
     CDS             10871..11614
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042696.2"
                     /locus_tag="ACTIVE_RS44140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8845"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_216858167.1"
                     /transl_table=11
                     /translation="MERDVRELRGAWSRYQRHTFHDPSPALAPWVERYWEARWDYAEPY
                     RQKIVPYPNVHLSFGSGRADVNGVCSGYRIKVLEGRDHVFGVAFRPGCFRPFLGAAVST
                     ITDRVVPAAEVFGPDLPATLDVPTVEAFLLEHLPDDDPRVRQAVASVELIAQDKAVTRV
                     ERLADELGLSVRGLQRLFAEYVGIGPKWVIRRYRLHEATERMAAGGAIEWAALAADLGY
                     VDQGHFIRDFKGMFGEQPTWYAQRY"
     gene            complement(11958..12632)
                     /locus_tag="ACTIVE_RS44145"
                     /old_locus_tag="ACTIVE_8846"
     CDS             complement(11958..12632)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="ACTIVE_RS44145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8846"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_173100513.1"
                     /transl_table=11
                     /translation="MRGVLSALESASQFYRVTAIQTAGEVDALLQETCEPPILLLALPQ
                     IIDDRFIDDLRRWTERSLVLGISQMLDRDRLATLIRAGLHGHLDMTTEAGTLILALSIV
                     APDRFLLFGPVGGELFCEPAGPPAPASVVLQSGLTQREGQVLTLVAEGWTHKQISSKLG
                     LSKATIDTYVQRIRQKLGLRNKADLTRAAVHYGLGTPEIPPASPRAPEMSSAQIKRHAG
                     SR"
     misc_feature    complement(12303..12305)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12697..12713)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.6"
                     /tool="antismash"
     gene            complement(12760..13512)
                     /locus_tag="ACTIVE_RS44150"
                     /old_locus_tag="ACTIVE_8847"
     CDS             complement(12760..13512)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Thioesterase (20-224). E-value: 3.6e-35.
                     Score: 114.4. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS44150_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.4"
                     /locus_tag="ACTIVE_RS44150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8847"
                     /product="thioesterase"
                     /protein_id="WP_173100514.1"
                     /sec_met_domain="Thioesterase (E-value: 9.3e-33, bitscore:
                     113.4, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGDGLWLTRLTGDPAEPAIRLFAFPNAGAGPNVFTGLARRLPGW
                     IDLWAVALPGREARFGEPPRTELAPLTAELADALLPHLSRPYALFGDCSGALLAFLVAH
                     RVRELGGPAPVRLVVRAYPPPDIVNRTPRELLALESAEFWRRLVSQGRIPPEIAAIDDM
                     REVFEPAFRADYRLLAQYEYRPMPPLNTAITSLPGPGDPDARRHAAGWAAHGKGDPHHR
                     EVGNGGRATDSPAALGAHLAQTLGDLAP"
     aSDomain        complement(12841..13452)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS44150_Thioesterase.1"
                     /evalue="3.60E-35"
                     /label="ACTIVE_RS44150_Thioesterase.1"
                     /locus_tag="ACTIVE_RS44150"
                     /protein_end="224"
                     /protein_start="20"
                     /score="114.4"
                     /tool="antismash"
                     /translation="RLFAFPNAGAGPNVFTGLARRLPGWIDLWAVALPGREARFGEPPR
                     TELAPLTAELADALLPHLSRPYALFGDCSGALLAFLVAHRVRELGGPAPVRLVVRAYPP
                     PDIVNRTPRELLALESAEFWRRLVSQGRIPPEIAAIDDMREVFEPAFRADYRLLAQYEY
                     RPMPPLNTAITSLPGPGDPDARRHAAGWAAHGKGDPHHREV"
     CDS_motif       complement(13198..13260)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44150_0001"
                     /evalue="1.20E-04"
                     /label="NRPS-te1"
                     /locus_tag="ACTIVE_RS44150"
                     /protein_end="105"
                     /protein_start="84"
                     /score="14.6"
                     /tool="antismash"
                     /translation="RPYALFGDCSGALLAFLVAHR"
     gene            complement(13509..13763)
                     /locus_tag="ACTIVE_RS44155"
                     /old_locus_tag="ACTIVE_8848"
     CDS             complement(13509..13763)
                     /NRPS_PKS="Domain: PCP (12-79). E-value: 3.5e-23. Score:
                     73.6. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS44155_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="ACTIVE_RS44155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8848"
                     /product="acyl carrier protein"
                     /protein_id="WP_173100515.1"
                     /sec_met_domain="PP-binding (E-value: 7.9e-17, bitscore:
                     60.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGFAMAPDDTDAELRAIWEEVLGCPVGDHESFFELGGDSLTAAR
                     ILTRVRERLGHSLTILDIFDAPTLGDFSAVVGRSAPHRE"
     aSDomain        complement(13527..13727)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS44155_PCP.1"
                     /evalue="3.50E-23"
                     /label="ACTIVE_RS44155_PCP.1"
                     /locus_tag="ACTIVE_RS44155"
                     /protein_end="79"
                     /protein_start="12"
                     /score="73.6"
                     /tool="antismash"
                     /translation="AELRAIWEEVLGCPVGDHESFFELGGDSLTAARILTRVRERLGHS
                     LTILDIFDAPTLGDFSAVVGRS"
     CDS_motif       complement(13641..13670)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44155_0001"
                     /evalue="2.00E-04"
                     /label="PCP_mC"
                     /locus_tag="ACTIVE_RS44155"
                     /protein_end="41"
                     /protein_start="31"
                     /score="14.3"
                     /tool="antismash"
                     /translation="SFFELGGDSL"
     misc_feature    13788..13802
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.16"
                     /tool="antismash"
     gene            14012..15031
                     /locus_tag="ACTIVE_RS44160"
                     /old_locus_tag="ACTIVE_8849"
     CDS             14012..15031
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="ACTIVE_RS44160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8849"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_216858168.1"
                     /transl_table=11
                     /translation="MSGRVAVALTDVAKHFRQGRRTVAQRIRRAPDTRREVPAIDGVDL
                     AVRDREVFGLVGPNGAGKSTTVRVIATLLEPTRGTVEVCGVDAVAHPREARRHLGVVIG
                     GERSVYWKLTGRENLEYFAALYHLPPRETPGRIERVLRDVELLDRADDYAERYSTGMRQ
                     RLSLARALLQEPAVLLLDEPTSGLDPRSAERLREQVRRLRDAGHCVLITTHDMAEADQV
                     CDRVAVIDRGRVARLGTPAELKRLVKANQVARVRLVLRDRAGDSDLLESVGRFATVADK
                     SVDGLHAEMTLHLAPGVDLLPRLVEAANRHGATIHGVDVEPVTLHDVFLAVTAPGTAG"
     gene            15028..15867
                     /locus_tag="ACTIVE_RS44165"
                     /old_locus_tag="ACTIVE_8850"
     CDS             15028..15867
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024110.4"
                     /locus_tag="ACTIVE_RS44165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8850"
                     /product="ABC transporter permease"
                     /protein_id="WP_173100516.1"
                     /transl_table=11
                     /translation="MNRAEAELRAIAATTRKELRLMRRYPAEIVALAVWMLLLPLAYIA
                     QARAFSGGGPASVAAFERRAGTDDYVAFLYLGWSVYLWITAVLWGPGLALRQERQRGSF
                     ETMFASPASRFTLLFGGAPAQIVPVLVVFASAAASMRLLFGVPLDGGDLVRWLAVLALA
                     FPVLMALGAVFATASLSLQDASGALQISRGAFTLLCGVTYPLAVLPEPLRAVGEALPPT
                     QVLDALRAVTAGHEGLAARLPGLAVLLGEAVVAAALAMALLWLSVRHARRAGKLGLF"
     gene            15867..17513
                     /locus_tag="ACTIVE_RS44170"
                     /old_locus_tag="ACTIVE_8851"
     CDS             15867..17513
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS44170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_8851"
                     /product="hypothetical protein"
                     /protein_id="WP_173100517.1"
                     /transl_table=11
                     /translation="MAGTTGREGPLTWYQEAVWWSQYWNPPDETYPPMADVWYLPERPP
                     AEAVHAVFAELAARHEVLRTSLPLGEDGLPHQRLHAPGAMPVPLRSVPLGELREDVAGV
                     LGGFRRPGAGDPDGPRWRAVLGVKEGRVPAVAFAGDRSVMDGGAVAGLRHQFLTALRGR
                     RGVPPGALVQPLARADHERSAAGRAKADAALGRLADVFGRAPGPLFTGPPAPPGTPRYV
                     EASTRSPELAARAAQAARIHRVTLPSIVLAAFSSVLALRTGRSVVPIRSLCANRTTGAE
                     RASVLGLYQPAYLVLDLSGDPLMSDVVRRTWRESLSAYAHSEYPPDEFRETVVRAARGR
                     GFVPEFQLDYDFLPAPGPATGRPPAGGAVENAEPPVEHAGSDQGRPDYALFQARVLGEE
                     LMLALDADTALVPRAEIDRLLSWTVRALFRLADASAGAMRCGEFGAAIGLEPKAAEGAQ
                     EPPVAAGAAADPAAERALREAFLTAHRGVGDVDLRDDYVAAGGRLRRVPRTVRALAGHG
                     FGGLRAEHVETPVSLRTVAAALRREPCEAGR"
     misc_feature    17292..17294
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17510..18973
                     /locus_tag="ACTIVE_RS44175"
                     /old_locus_tag="ACTIVE_8852"
     CDS             17510..18973
                     /NRPS_PKS="Domain: AMP-binding (11-389). E-value: 7.7e-46.
                     Score: 148.4. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS44175_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="ACTIVE_RS44175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8852"
                     /product="AMP-binding protein"
                     /protein_id="WP_173100518.1"
                     /sec_met_domain="AMP-binding (E-value: 2.5e-44, bitscore:
                     150.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGGAVPAAERFRELARDRPDKPALIVDGGPAAPDTVVSREALDA
                     ASADLAARLAASAAATPRPPVVVIDAANDARTVIAFAACMRARLPFLPLDPLMPEAEAA
                     RVLDALSAHRSPVAVEDTASPAGRPHAATGRGGYLLATGGSSGTPRLIEHPRPLDHDPA
                     RVPNAMLRAVGWRSGQRQLIAGPLHHAAPFMCCWEGLLGGDTLVVLPRFDPRRMLRAID
                     EHAIEWAQLTPVHLQWGLAALERSAYSLRSLNAVMHTAAPCPAEVKRAWIDLLGPTRLY
                     EVYGATEAVGTTLLRGDEWLERPGSVGRGFCTQIRIVDEDGRLVPPGVEGEVLMRRTTG
                     RDAVGRELGGASGGVRWTVDGFAGVGDVGRLDASGHLYLAARRHDMVIVGGGNVYPAEV
                     EAALAEHPDILDVAAVGRADGQLGGGLLALVIKRPGSALTEAAVADFARGRLAPHKVPW
                     TVRFVTELPRTEAGKLHRRRLAEQEVTGV"
     aSDomain        17543..18676
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS44175_AMP-binding.1"
                     /evalue="7.70E-46"
                     /label="ACTIVE_RS44175_AMP-binding.1"
                     /locus_tag="ACTIVE_RS44175"
                     /protein_end="389"
                     /protein_start="11"
                     /score="148.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FRELARDRPDKPALIVDGGPAAPDTVVSREALDAASADLAARLAA
                     SAAATPRPPVVVIDAANDARTVIAFAACMRARLPFLPLDPLMPEAEAARVLDALSAHRS
                     PVAVEDTASPAGRPHAATGRGGYLLATGGSSGTPRLIEHPRPLDHDPARVPNAMLRAVG
                     WRSGQRQLIAGPLHHAAPFMCCWEGLLGGDTLVVLPRFDPRRMLRAIDEHAIEWAQLTP
                     VHLQWGLAALERSAYSLRSLNAVMHTAAPCPAEVKRAWIDLLGPTRLYEVYGATEAVGT
                     TLLRGDEWLERPGSVGRGFCTQIRIVDEDGRLVPPGVEGEVLMRRTTGRDAVGRELGGA
                     SGGVRWTVDGFAGVGDVGRLDASGHLYLAARRHDMVIV"
     gene            18966..19574
                     /locus_tag="ACTIVE_RS44180"
                     /old_locus_tag="ACTIVE_8853"
     CDS             18966..19574
                     /NRPS_PKS="Domain: PCP (131-196). E-value: 8.8e-17. Score:
                     53.1. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS44180_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="ACTIVE_RS44180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8853"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_173100519.1"
                     /sec_met_domain="PP-binding (E-value: 5.1e-12, bitscore:
                     45.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDLDDGAGGPADAGGRPPAGGTDTVVPGLGTRRVEGVLRAHPDV
                     REAVLLPSGGDGPGETALVVPHGYAVGPELAAHVAAELGIAAIPATIALLPEIPRGPDG
                     TPDAAAVRERLASWPAVYRFELPRTSAERRVAALWCRVLDRGWVGVHDDFIELGGDSRT
                     AALLLAELRAEPGADVTMGDLFELATVARLAERFGPSDD"
     aSDomain        19359..19553
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS44180_PCP.1"
                     /evalue="8.80E-17"
                     /label="ACTIVE_RS44180_PCP.1"
                     /locus_tag="ACTIVE_RS44180"
                     /protein_end="196"
                     /protein_start="131"
                     /score="53.1"
                     /tool="antismash"
                     /translation="ERRVAALWCRVLDRGWVGVHDDFIELGGDSRTAALLLAELRAEPG
                     ADVTMGDLFELATVARLAER"
     gene            19567..20004
                     /locus_tag="ACTIVE_RS44185"
                     /old_locus_tag="ACTIVE_8854"
     CDS             19567..20004
                     /NRPS_PKS="Domain: PCP (73-142). E-value: 1.6e-23. Score:
                     74.7. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS44185_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="ACTIVE_RS44185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8854"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_173100520.1"
                     /sec_met_domain="PP-binding (E-value: 2.1e-13, bitscore:
                     49.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEAPAGGRPSGDDLAAELRRHAARLLPAAMVPSLIVELPELPRT
                     PSGKLDRAALPAPDAARGPVRAEPGDEREAALAEIFAEVLGLPAVGADDDFFRLGGTSV
                     HAVRALAGMSARFGTRVPPLRFFQEPTVRRLARVLREGGGS"
     aSDomain        19786..19992
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS44185_PCP.1"
                     /evalue="1.60E-23"
                     /label="ACTIVE_RS44185_PCP.1"
                     /locus_tag="ACTIVE_RS44185"
                     /protein_end="142"
                     /protein_start="73"
                     /score="74.7"
                     /tool="antismash"
                     /translation="EAALAEIFAEVLGLPAVGADDDFFRLGGTSVHAVRALAGMSARFG
                     TRVPPLRFFQEPTVRRLARVLREG"
     gene            20001..22721
                     /locus_tag="ACTIVE_RS44190"
                     /old_locus_tag="ACTIVE_8855"
     CDS             20001..22721
                     /NRPS_PKS="Domain: Condensation_LCL (18-307). E-value:
                     1.6e-80. Score: 262.3. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS44190_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (470-856). E-value: 6e-99.
                     Score: 323.3. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS44190_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="ACTIVE_RS44190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8855"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_173100521.1"
                     /sec_met_domain="Condensation (E-value: 1.6e-63, bitscore:
                     213.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2e-107, bitscore:
                     358.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSDAREAAPAASAYAPPPVQETMWLRERLLPGTAMHNLAAAHEI
                     DGPVDAAVLAAAVRTVAARHEALRTTFHEVAGRPEARVHADAPVELAEVDATGRADWRD
                     PARAEATRPFDLTRPPLLRALLFRRPAGRSALVLVVHHLVADAWSLGILWEEIGDAYNA
                     GLRGEPWMPPPPPLSYGDHARRENAARGAGRRDRTAAFWRDRLATAPPFTVVPPDRPRP
                     AGAATGGATHEVRLDAGLRDRLAAFASARRASPFMVLAAVWSAVLARYAGQDDVVFGVP
                     ASGRDRPDLERVVGLFASPFPLRAAVDVAEPFEALLARVRRELLESMAHQDVSMLELAD
                     AARAPRQLDTTPVFQILFTLFRTDHRPLELAGARCRYVSGLVEAVQTDLALTATMPNTG
                     ELRFQLHYSTGLYDAETARCLLGCVGELLRDALERPGVPLRELRMTGGSPAPAAVRPAA
                     DAAGGETAPEMVRRVAAAVPGAVAVSDGTRSLTYAELERRVERFAGRLRAAGAGRGDLV
                     ALLLPRGADLVVAMLGAWRAGAAYLPLDPAHPPDRLASLLADARPAVAVGSSASGAPVP
                     SGLPVLPMDRDGGQATASAGPPHDPAPGDLAYVIHTSGSTGGPKGVEVPHRAVAHLFRA
                     MARRPGLDRTDAVLALTNPTFDISLAELVLPLSVGARVVIAPPGAEHDPRAVAGLVRDT
                     EVTTVQATPTGWRNLLLAAPAGRWLRRAWCGGEALDAALADRLTGLAGEAWNLYGPTET
                     TVWSLAARLRPGAGTVPLGTPLGDTTATVRDGWLEPAPPGVAGELWIGGPGVARAYRDR
                     PALTAERFVPDAGGAVTYRTGDLVRRRPGGGLEYLGRTDRQVKLNGHRIEPGEVEAVLR
                     AHPAIADAAVVLRDDLPGGPRLVAYVTRRPGGGAP"
     aSDomain        20055..20921
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS44190_Condensation_LCL.
                     1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.60E-80"
                     /label="ACTIVE_RS44190_Condensation_LCL.1"
                     /locus_tag="ACTIVE_RS44190"
                     /protein_end="307"
                     /protein_start="18"
                     /score="262.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLVADA"
                     /tool="antismash"
                     /translation="PVQETMWLRERLLPGTAMHNLAAAHEIDGPVDAAVLAAAVRTVAA
                     RHEALRTTFHEVAGRPEARVHADAPVELAEVDATGRADWRDPARAEATRPFDLTRPPLL
                     RALLFRRPAGRSALVLVVHHLVADAWSLGILWEEIGDAYNAGLRGEPWMPPPPPLSYGD
                     HARRENAARGAGRRDRTAAFWRDRLATAPPFTVVPPDRPRPAGAATGGATHEVRLDAGL
                     RDRLAAFASARRASPFMVLAAVWSAVLARYAGQDDVVFGVPASGRDRPDLERVVGLFAS
                     PFPLRAAV"
     aSModule        20055..22568
                     /domains="nrpspksdomains_ACTIVE_RS44190_Condensation_LCL.1"
                     /domains="nrpspksdomains_ACTIVE_RS44190_AMP-binding.1"
                     /incomplete
                     /locus_tags="ACTIVE_RS44190"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20106..20219
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44190_0001"
                     /evalue="2.00E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="ACTIVE_RS44190"
                     /protein_end="73"
                     /protein_start="35"
                     /score="45.9"
                     /tool="antismash"
                     /translation="MHNLAAAHEIDGPVDAAVLAAAVRTVAARHEALRTTFH"
     CDS_motif       20418..20483
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44190_0002"
                     /evalue="1.20E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="ACTIVE_RS44190"
                     /protein_end="161"
                     /protein_start="139"
                     /score="27.4"
                     /tool="antismash"
                     /translation="VHHLVADAWSLGILWEEIGDAY"
     CDS_motif       20823..20912
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44190_0003"
                     /evalue="1.20E-11"
                     /label="C5_LCL_267-296"
                     /locus_tag="ACTIVE_RS44190"
                     /protein_end="304"
                     /protein_start="274"
                     /score="37.0"
                     /tool="antismash"
                     /translation="DVVFGVPASGRDRPDLERVVGLFASPFPLR"
     CDS_motif       20961..21080
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44190_0004"
                     /evalue="1.70E-07"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ACTIVE_RS44190"
                     /protein_end="360"
                     /protein_start="320"
                     /score="23.5"
                     /tool="antismash"
                     /translation="RRELLESMAHQDVSMLELADAARAPRQLDTTPVFQILFTL"
     aSDomain        21411..22568
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS44190_AMP-binding.1"
                     /evalue="6.00E-99"
                     /label="ACTIVE_RS44190_AMP-binding.1"
                     /locus_tag="ACTIVE_RS44190"
                     /protein_end="856"
                     /protein_start="470"
                     /score="323.3"
                     /specificity="substrate consensus: Gly"
                     /tool="antismash"
                     /translation="RRVAAAVPGAVAVSDGTRSLTYAELERRVERFAGRLRAAGAGRGD
                     LVALLLPRGADLVVAMLGAWRAGAAYLPLDPAHPPDRLASLLADARPAVAVGSSASGAP
                     VPSGLPVLPMDRDGGQATASAGPPHDPAPGDLAYVIHTSGSTGGPKGVEVPHRAVAHLF
                     RAMARRPGLDRTDAVLALTNPTFDISLAELVLPLSVGARVVIAPPGAEHDPRAVAGLVR
                     DTEVTTVQATPTGWRNLLLAAPAGRWLRRAWCGGEALDAALADRLTGLAGEAWNLYGPT
                     ETTVWSLAARLRPGAGTVPLGTPLGDTTATVRDGWLEPAPPGVAGELWIGGPGVARAYR
                     DRPALTAERFVPDAGGAVTYRTGDLVRRRPGGGLEYLGRTDRQVKL"
     CDS_motif       21594..21635
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44190_0005"
                     /evalue="1.40E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ACTIVE_RS44190"
                     /protein_end="545"
                     /protein_start="531"
                     /score="15.2"
                     /tool="antismash"
                     /translation="LGAWRAGAAYLPLD"
     CDS_motif       21819..21878
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44190_0006"
                     /evalue="2.80E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ACTIVE_RS44190"
                     /protein_end="626"
                     /protein_start="606"
                     /score="26.0"
                     /tool="antismash"
                     /translation="AYVIHTSGSTGGPKGVEVPH"
     CDS_motif       22371..22460
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44190_0007"
                     /evalue="1.50E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ACTIVE_RS44190"
                     /protein_end="820"
                     /protein_start="790"
                     /score="52.4"
                     /tool="antismash"
                     /translation="PPGVAGELWIGGPGVARAYRDRPALTAERF"
     CDS_motif       22536..22601
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44190_0008"
                     /evalue="3.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ACTIVE_RS44190"
                     /protein_end="867"
                     /protein_start="845"
                     /score="35.2"
                     /tool="antismash"
                     /translation="YLGRTDRQVKLNGHRIEPGEVE"
     gene            22718..24301
                     /locus_tag="ACTIVE_RS44195"
                     /old_locus_tag="ACTIVE_8856"
     CDS             22718..24301
                     /NRPS_PKS="Domain: AMP-binding (10-424). E-value: 2.1e-79.
                     Score: 258.9. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS44195_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890179.1"
                     /locus_tag="ACTIVE_RS44195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8856"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_173100522.1"
                     /sec_met_domain="AMP-binding (E-value: 2.9e-84, bitscore:
                     282.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGGSLYSWFAAGAARHPDAVALETGNASWTYAELERAAAATAAL
                     MAPRRGEPPRRVGLLCSRTLPAYAGYLAALRLGAAVVPLAPGYPAPRNRAMAEATGIDV
                     LLTDEFEAARAAGIAAAAGARVVELPGSPRGLAQTSSPPAPASVEPDDIAYILFTSGST
                     GVPKGVPVTHANVTAFLRSCAERYPVVKGDRASHTFELTFDPSVCDLFLAWSGGATVVV
                     PVGNEALRPSAYVNRRGITHWFSVPYAVSLGLRAGGVEPGSMPGLRRTRFGGDRLTARQ
                     AAAWAEAAPHSAIENTYGPTEAAVFSTAYELPRSPSNWPATSNGTVPIGRPLPTVEHVV
                     IGPDGRPAAEGELCLRGEQRFPGYLDPRSDAGRFYALPPAAPARVPCRPGPYGPEHWYR
                     TGDRVRVEDGLLVHLGRLDQQVKVRGYRVEPGEVEAVLRRHPDVADAVVFPAGDGDGRG
                     LAAVYTGRPVPAADLAAAVLGALPPHMLPGSFEHRAVLPVNGNGKVDRARAAAEGAGAP
                     WPPGTPHAAP"
     aSDomain        22748..23989
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS44195_AMP-binding.1"
                     /evalue="2.10E-79"
                     /label="ACTIVE_RS44195_AMP-binding.1"
                     /locus_tag="ACTIVE_RS44195"
                     /protein_end="424"
                     /protein_start="10"
                     /score="258.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="AAGAARHPDAVALETGNASWTYAELERAAAATAALMAPRRGEPPR
                     RVGLLCSRTLPAYAGYLAALRLGAAVVPLAPGYPAPRNRAMAEATGIDVLLTDEFEAAR
                     AAGIAAAAGARVVELPGSPRGLAQTSSPPAPASVEPDDIAYILFTSGSTGVPKGVPVTH
                     ANVTAFLRSCAERYPVVKGDRASHTFELTFDPSVCDLFLAWSGGATVVVPVGNEALRPS
                     AYVNRRGITHWFSVPYAVSLGLRAGGVEPGSMPGLRRTRFGGDRLTARQAAAWAEAAPH
                     SAIENTYGPTEAAVFSTAYELPRSPSNWPATSNGTVPIGRPLPTVEHVVIGPDGRPAAE
                     GELCLRGEQRFPGYLDPRSDAGRFYALPPAAPARVPCRPGPYGPEHWYRTGDRVRVEDG
                     LLVHLGRLDQQVKVR"
     CDS_motif       23177..23236
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44195_0001"
                     /evalue="6.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ACTIVE_RS44195"
                     /protein_end="173"
                     /protein_start="153"
                     /score="31.0"
                     /tool="antismash"
                     /translation="AYILFTSGSTGVPKGVPVTH"
     CDS_motif       23762..23839
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44195_0002"
                     /evalue="5.20E-03"
                     /label="NRPS-A_a6"
                     /locus_tag="ACTIVE_RS44195"
                     /protein_end="374"
                     /protein_start="348"
                     /score="9.3"
                     /tool="antismash"
                     /translation="AEGELCLRGEQRFPGYLDPRSDAGRF"
     CDS_motif       23954..24019
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44195_0003"
                     /evalue="2.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ACTIVE_RS44195"
                     /protein_end="434"
                     /protein_start="412"
                     /score="35.8"
                     /tool="antismash"
                     /translation="HLGRLDQQVKVRGYRVEPGEVE"
     gene            24328..25008
                     /locus_tag="ACTIVE_RS44200"
                     /old_locus_tag="ACTIVE_8857"
     CDS             24328..25008
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS44200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_8857"
                     /product="GNAT family protein"
                     /protein_id="WP_173100523.1"
                     /transl_table=11
                     /translation="MIGTLTTLEHCLPGDYERLAKWFSSASGWYALGKQKLFSADDLRN
                     ENLHGRTHFLIVVENGSKRRVGAVTWTEKEEYEGSYVIGTGVGDPELYDRGLGAEATVL
                     LLNYLFHMKNAHRIEFIFGLYNKHALPALTQWNVTLEGILRDYFYLDGEYQDAALCSVL
                     REEFYEFAAAGGFLSTLDEIPRADKEEARARVSEHLAKMPDRHLADLFGRSRPVAPHRR
                     ERPL"
     misc_feature    24371..24389
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.84"
                     /tool="antismash"
     misc_feature    24372..24388
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.22"
                     /tool="antismash"
     gene            25106..25444
                     /locus_tag="ACTIVE_RS44205"
                     /old_locus_tag="ACTIVE_8858"
     CDS             25106..25444
                     /NRPS_PKS="Domain: PP-binding (11-74). E-value: 7.3e-13.
                     Score: 40.6. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS44205_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="ACTIVE_RS44205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8858"
                     /product="acyl carrier protein"
                     /protein_id="WP_216858169.1"
                     /sec_met_domain="PP-binding (E-value: 5.3e-09, bitscore:
                     35.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHEVESAMLGIVRDAWEKRLGKRGLGVEVNFFDFGGTSRIIAEVR
                     ADLMAGLGREIPLVAFYRHQNIRALARHLAGGADASPEAGRARRPAPGGRQRALRGAAR
                     ARRTEGEA"
     aSDomain        25139..25327
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS44205_PP-binding.1"
                     /evalue="7.30E-13"
                     /label="ACTIVE_RS44205_PP-binding.1"
                     /locus_tag="ACTIVE_RS44205"
                     /protein_end="74"
                     /protein_start="11"
                     /score="40.6"
                     /tool="antismash"
                     /translation="VRDAWEKRLGKRGLGVEVNFFDFGGTSRIIAEVRADLMAGLGREI
                     PLVAFYRHQNIRALARHL"
     gene            25445..30940
                     /locus_tag="ACTIVE_RS44210"
                     /old_locus_tag="ACTIVE_8859"
     CDS             25445..30940
                     /EC_number="6.4.-.-"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (9-433). E-value:
                     1.6e-151. Score: 497.0. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS44210_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (532-820). E-value: 1.2e-102.
                     Score: 335.3. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS44210_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1142-1338). E-value: 1.1e-58.
                     Score: 190.2. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS44210_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_DH2 (1391-1597). E-value: 3.8e-32.
                     Score: 103.5. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS44210_PKS_DH2.1"
                     /NRPS_PKS="Domain: PCP (1759-1827). E-value: 3.6e-23.
                     Score: 73.5. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS44210_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012901.4"
                     /locus_tag="ACTIVE_RS44210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8859"
                     /product="type I polyketide synthase"
                     /protein_id="WP_173100524.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.3e-63, bitscore:
                     213.9, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 1.3e-156, bitscore:
                     520.8, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.8e-100, bitscore:
                     335.3, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 3.7e-43, bitscore:
                     146.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.8e-16, bitscore:
                     58.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADDIRENDVAIVGMACRFPGANDVREYWDNLVKGVEAIRFLTDD
                     ELRAAGVPERFVNDPNYVKACPMIDDMDGFDAAFFGYTARDAELRDPQGRLFLETCHSA
                     LEDAGYDVGRYSGTVGVFGGAGEYRYGSDNVRRNGAAVDAAGGMSVATATEPDYLATTV
                     SYRLGLQGPSFTVQTACSTALVAIHLGCQSLQMGECDMALVGAVDVRLPYGRGHWRVDG
                     GIGSADGHVRAFDAAASGTIFGSGVGVLAVKRLADARADGDHVYAVIRGSAINNDGAAR
                     AGYTAPGVEGQTRLIVEALAVAQVPPETIGYVEAHGTGTLVGDPIEVTALSDAFRAAGA
                     TAAQYCALGSVKTNVGHLGAAAGVAGIIKACLAVRHGVIPPTLHFQEPNPAIDFESSPF
                     YVNTEPVPWTGPRRAGVSSFGIGGTNAHIVLEEPPEHVRVPDERSSPQVIALSARTGGA
                     LAAMAARLGEHLGEPDPPPLADVAWTLQHGRREFPYRRTVVAATVQDAAAALRDLAGAA
                     ASTRPVPVDGRGVALLFPGQGAQYPGMGEGLYRTQKAFRTVIDDCAEVLEPLIGADLRD
                     LLYGGAPDEALARTRLAQPALFAVEYAVARLFASWGVVPDALLGHSIGEYTAACLAGVM
                     SFEDALAVVAARGELMQGMPPGSMAAVPLPEHLVVPMLLGGVEVAAVNGPAATVVAGPD
                     AAVDAFEKRLAPWGVRCGRLVTSHAFHSGMMDAIVEPFRERVASVRLNEPRIPFLSNVT
                     GTWITAEQATDPGYWAAHLRSAVRFADCVRALADGADRVLLEAGPGRTLTGAARQCLPG
                     ARTVLATSMRHPLGEGDDEVLALEALGRLWSAGVPVGWDGAASGDRRRVPLPVYPFERR
                     RYWLDPDPAGTAGQDAEEHDEGARPVERAVYAPVWTERPIGTEIPAVPDGSRWLVLTPG
                     TGPVEDLADRLEAEGARVVRVTAGPGFAETGADRFAVRPAERDDYEALLGALGDGAFPT
                     HVVHGWTATAAEPDPLAPEAVERACDLGFYSLLLLAQALEDRLPDEPVRIVAVSTNMQD
                     VSGEGANEPGKATLLGPAILMNRELRHVGCRSVDLAAPARQPADVVTGQLLRECLRDDD
                     ADRQVAWRGLKRWAWSYTGVPVEVPEEKPAVLREGGTYLITGGLGGIGLTTARELARTA
                     RANLVLLGRTAPPDRDAWPALLADEGTDEATRRLLGELAEIEELGGTVLARACDVTDED
                     ALAAAVAEAVERFGRVDGVFHSAGVAGGGLLAVRDREAARRVLAPKVAGTLALHRVLGD
                     DVDFVVLYSSITSVVGDFGQVDYCAANNFLDSYARRRAASGARVLSVSWGAWRDVGMAV
                     DAARITPNVFREMRGGKWSEPAEHPLLGRRLHDLSDDVVFSTVLGPESHWMLTDHRVGA
                     IPLMPGSGCLEMIRAAAVTALGAAADEHVEMTDVVFLGPIEVRTDQEMRITLRPAQDGF
                     HDASFTVAPADTDDPAAWTERVRARVRTVPATPAPVHDVEAVRAECADHRFEPTPDFRS
                     RGIVDFGPHWYSVERVDIGARRQLGTVALPEEFRAECGQYVLHPGLFDDAVSNARVIEG
                     IRKGNKYLPLSYRRILVRAPLPPRFHVDVRELDDAEGEIVAADIRVMAPDGTELAEIEQ
                     YALRRVDPAAFAEGAGGDEGAPAEPGPAGAPAPAAAPDRADWMITPATGMDALRALLGA
                     WGAAPHLVVCPEGLEANLRRVESLTGDVLERELGDGAVVATTAAQGERLLDTPYAAPET
                     PLQQRIAALWSDAFGIREIGLDDDFAELGGNSLMAVQLAWRVRQHFDVEVTVARLFRRP
                     TVRALAELVENEQGAR"
     aSDomain        25472..26743
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS44210_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="1.60E-151"
                     /label="ACTIVE_RS44210_PKS_KS.1"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="433"
                     /protein_start="9"
                     /score="497.0"
                     /tool="antismash"
                     /translation="VAIVGMACRFPGANDVREYWDNLVKGVEAIRFLTDDELRAAGVPE
                     RFVNDPNYVKACPMIDDMDGFDAAFFGYTARDAELRDPQGRLFLETCHSALEDAGYDVG
                     RYSGTVGVFGGAGEYRYGSDNVRRNGAAVDAAGGMSVATATEPDYLATTVSYRLGLQGP
                     SFTVQTACSTALVAIHLGCQSLQMGECDMALVGAVDVRLPYGRGHWRVDGGIGSADGHV
                     RAFDAAASGTIFGSGVGVLAVKRLADARADGDHVYAVIRGSAINNDGAARAGYTAPGVE
                     GQTRLIVEALAVAQVPPETIGYVEAHGTGTLVGDPIEVTALSDAFRAAGATAAQYCALG
                     SVKTNVGHLGAAAGVAGIIKACLAVRHGVIPPTLHFQEPNPAIDFESSPFYVNTEPVPW
                     TGPRRAGVSSFGIGGTNAHIVLEEP"
     aSModule        25472..30925
                     /complete
                     /domains="nrpspksdomains_ACTIVE_RS44210_PKS_KS.1"
                     /domains="nrpspksdomains_ACTIVE_RS44210_PKS_AT.1"
                     /domains="nrpspksdomains_ACTIVE_RS44210_PKS_KR.1"
                     /domains="nrpspksdomains_ACTIVE_RS44210_PKS_DH2.1"
                     /domains="nrpspksdomains_ACTIVE_RS44210_PCP.1"
                     /locus_tags="ACTIVE_RS44210"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       25955..26002
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44210_0001"
                     /evalue="1.70E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="186"
                     /protein_start="170"
                     /score="17.0"
                     /tool="antismash"
                     /translation="GPSFTVQTACSTALVA"
     CDS_motif       26378..26425
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44210_0002"
                     /evalue="2.40E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="327"
                     /protein_start="311"
                     /score="13.2"
                     /tool="antismash"
                     /translation="YVEAHGTGTLVGDPIE"
     CDS_motif       26489..26533
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44210_0003"
                     /evalue="5.20E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="363"
                     /protein_start="348"
                     /score="9.7"
                     /tool="antismash"
                     /translation="GSVKTNVGHLGAAAG"
     aSDomain        27041..27904
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS44210_PKS_AT.1"
                     /evalue="1.20E-102"
                     /label="ACTIVE_RS44210_PKS_AT.1"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="820"
                     /protein_start="532"
                     /score="335.3"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFPGQGAQYPGMGEGLYRTQKAFRTVIDDCAEVLEPLIGADLRDL
                     LYGGAPDEALARTRLAQPALFAVEYAVARLFASWGVVPDALLGHSIGEYTAACLAGVMS
                     FEDALAVVAARGELMQGMPPGSMAAVPLPEHLVVPMLLGGVEVAAVNGPAATVVAGPDA
                     AVDAFEKRLAPWGVRCGRLVTSHAFHSGMMDAIVEPFRERVASVRLNEPRIPFLSNVTG
                     TWITAEQATDPGYWAAHLRSAVRFADCVRALADGADRVLLEAGPGRTLTGAARQCLPGA
                     RTVLATS"
     CDS_motif       27044..27091
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44210_0004"
                     /evalue="1.00E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="549"
                     /protein_start="533"
                     /score="18.0"
                     /tool="antismash"
                     /translation="FPGQGAQYPGMGEGLY"
     CDS_motif       27224..27259
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44210_0005"
                     /evalue="1.30E-03"
                     /label="PKSI-AT-M_m2"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="605"
                     /protein_start="593"
                     /score="11.6"
                     /tool="antismash"
                     /translation="QPALFAVEYAVA"
     CDS_motif       27278..27400
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44210_0006"
                     /evalue="9.50E-27"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="652"
                     /protein_start="611"
                     /score="85.4"
                     /tool="antismash"
                     /translation="GVVPDALLGHSIGEYTAACLAGVMSFEDALAVVAARGELMQ"
     CDS_motif       27482..27520
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44210_0007"
                     /evalue="3.40E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="692"
                     /protein_start="679"
                     /score="10.8"
                     /tool="antismash"
                     /translation="AAVNGPAATVVAG"
     CDS_motif       27743..27778
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44210_0008"
                     /evalue="2.90E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="778"
                     /protein_start="766"
                     /score="14.3"
                     /tool="antismash"
                     /translation="YWAAHLRSAVRF"
     aSDomain        28871..29458
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS44210_PKS_KR.1"
                     /evalue="1.10E-58"
                     /label="ACTIVE_RS44210_PKS_KR.1"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="1338"
                     /protein_start="1142"
                     /score="190.2"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GTYLITGGLGGIGLTTARELARTARANLVLLGRTAPPDRDAWPAL
                     LADEGTDEATRRLLGELAEIEELGGTVLARACDVTDEDALAAAVAEAVERFGRVDGVFH
                     SAGVAGGGLLAVRDREAARRVLAPKVAGTLALHRVLGDDVDFVVLYSSITSVVGDFGQV
                     DYCAANNFLDSYARRRAASGARVLSVSWGAWRD"
     CDS_motif       28874..28972
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44210_0009"
                     /evalue="6.60E-13"
                     /label="PKSI-KR_m1"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="1176"
                     /protein_start="1143"
                     /score="41.2"
                     /tool="antismash"
                     /translation="TYLITGGLGGIGLTTARELARTARANLVLLGRT"
     CDS_motif       29300..29407
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44210_0010"
                     /evalue="9.50E-17"
                     /label="PKSI-KR_m4"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="1321"
                     /protein_start="1285"
                     /score="53.5"
                     /tool="antismash"
                     /translation="VDFVVLYSSITSVVGDFGQVDYCAANNFLDSYARRR"
     aSDomain        29618..30235
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS44210_PKS_DH2.1"
                     /evalue="3.80E-32"
                     /label="ACTIVE_RS44210_PKS_DH2.1"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="1597"
                     /protein_start="1391"
                     /score="103.5"
                     /tool="antismash"
                     /translation="HWMLTDHRVGAIPLMPGSGCLEMIRAAAVTALGAAADEHVEMTDV
                     VFLGPIEVRTDQEMRITLRPAQDGFHDASFTVAPADTDDPAAWTERVRARVRTVPATPA
                     PVHDVEAVRAECADHRFEPTPDFRSRGIVDFGPHWYSVERVDIGARRQLGTVALPEEFR
                     AECGQYVLHPGLFDDAVSNARVIEGIRKGNKYLPLSYRRILVR"
     CDS_motif       29627..29701
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44210_0011"
                     /evalue="7.30E-07"
                     /label="PKSI-DH_m2"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="1419"
                     /protein_start="1394"
                     /score="21.8"
                     /tool="antismash"
                     /translation="LTDHRVGAIPLMPGSGCLEMIRAAA"
     aSDomain        30722..30925
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS44210_PCP.1"
                     /evalue="3.60E-23"
                     /label="ACTIVE_RS44210_PCP.1"
                     /locus_tag="ACTIVE_RS44210"
                     /protein_end="1827"
                     /protein_start="1759"
                     /score="73.5"
                     /tool="antismash"
                     /translation="QRIAALWSDAFGIREIGLDDDFAELGGNSLMAVQLAWRVRQHFDV
                     EVTVARLFRRPTVRALAELVENE"
     gene            30963..31961
                     /locus_tag="ACTIVE_RS44215"
                     /old_locus_tag="ACTIVE_8860"
     CDS             30963..31961
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012517.4"
                     /locus_tag="ACTIVE_RS44215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8860"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_173100525.1"
                     /transl_table=11
                     /translation="MTGSFIAADELRTAANPLLLGPGAHGLRATADRARMAEEAGAGQL
                     WLSQVPDEHDSALIAAGCAAATRSMRVGTAVTPVAGRHPVLAAQAASALADLSGGRFAL
                     GLGAGHPFINEFVLGLDPVPPVAAMREYLTIVRTLLREGRVDFVGRHHTAHASNVTGHG
                     ADVPILLGGMRPKMIELAAELADGLLLWLAPLRYVEEHVLPAVHDACARVGRDPATLPV
                     LVEVPVYLADDHPNLYSHLEGLITQYAMMPSYRHVFEASGFGDRLATGEIDRAMTDAIA
                     IAGDAAEIAGRLEEFRTLGCVPVPATAIGDRPLELDTPDAFARFLKAVCVA"
     gene            31954..32724
                     /locus_tag="ACTIVE_RS44220"
                     /old_locus_tag="ACTIVE_8861"
     CDS             31954..32724
                     /NRPS_PKS="Domain: Thioesterase (23-245). E-value: 7.8e-42.
                     Score: 136.2. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS44220_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.4"
                     /locus_tag="ACTIVE_RS44220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8861"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_173100526.1"
                     /sec_met_domain="Thioesterase (E-value: 3.8e-37, bitscore:
                     127.7, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.1e-13, bitscore:
                     51.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEPVAPPGRWTRFALPASAPRVRLICLPCAGGGATAYRSWVREL
                     AGAGVDVWPVQLPGRENRFEEDLPGSMEDLVEELLDQLGPALRAAPYALFGHSMGASIA
                     LALAFGARARGLPAPVRLFPSAGRPPNRPDPDPPAHSLPKAAFAERLRAYDAGSFLLRE
                     PELLEMFLPKLRGDFALFENYRPPDEEPLDCPFTVLGGLDDASVPAALLPAWADYTRGA
                     FEVRLVAGGHLFLDSARDAVVRLVRGRLVPEAAG"
     aSDomain        32023..32688
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS44220_Thioesterase.1"
                     /evalue="7.80E-42"
                     /label="ACTIVE_RS44220_Thioesterase.1"
                     /locus_tag="ACTIVE_RS44220"
                     /protein_end="245"
                     /protein_start="23"
                     /score="136.2"
                     /tool="antismash"
                     /translation="RLICLPCAGGGATAYRSWVRELAGAGVDVWPVQLPGRENRFEEDL
                     PGSMEDLVEELLDQLGPALRAAPYALFGHSMGASIALALAFGARARGLPAPVRLFPSAG
                     RPPNRPDPDPPAHSLPKAAFAERLRAYDAGSFLLREPELLEMFLPKLRGDFALFENYRP
                     PDEEPLDCPFTVLGGLDDASVPAALLPAWADYTRGAFEVRLVAGGHLFLDSARDAVVRL
                     "
     CDS_motif       32224..32277
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS44220_0001"
                     /evalue="7.10E-06"
                     /label="NRPS-te1"
                     /locus_tag="ACTIVE_RS44220"
                     /protein_end="108"
                     /protein_start="90"
                     /score="18.6"
                     /tool="antismash"
                     /translation="PYALFGHSMGASIALALA"
     gene            32721..33548
                     /locus_tag="ACTIVE_RS44225"
                     /old_locus_tag="ACTIVE_8862"
     CDS             32721..33548
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013245.4"
                     /locus_tag="ACTIVE_RS44225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8862"
                     /product="ABC transporter permease"
                     /protein_id="WP_173100527.1"
                     /transl_table=11
                     /translation="MSPDGRALLAVARKELRVLRRYPLTLLNTMLFMPLYQLVLPVLLL
                     GTAFLVKGRSLGMDELTGTSDFGGWLSAGLVGATVTGTVLSGPAQAMASERGLGTLEQT
                     WAMPVSRRALVLGLMTCMTGLSLLAGVTMAVLVSLLAGAHYGPGTVLVLPVFAALVPGL
                     AGMGLLSASLSLLWRQAVGLTDNLGYVVTVLAGVTFPVAVLWDALRPVSYLIPTTWAID
                     LSRRAALGADSLYPPAVEACALLATSGLFLAGGSALFGRMERRMRAEGALGQH"
     misc_feature    33602..33617
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.76"
                     /tool="antismash"
     misc_feature    complement(33605..33620)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.18"
                     /tool="antismash"
     gene            33636..34628
                     /locus_tag="ACTIVE_RS44230"
                     /old_locus_tag="ACTIVE_8863"
     CDS             33636..34628
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS44230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_8863"
                     /product="hypothetical protein"
                     /protein_id="WP_173100528.1"
                     /transl_table=11
                     /translation="MSVTPEIGSQAEPGAAGHNLRQVFPDGEIFVVSDDAELNRYAAGL
                     GMRALPLEDASGLPDDANVVLLLRARLVSRDLRRLFRRMRVLLVPIASFDPSLAVAEYT
                     LRLVRATDYTAACEWNRYWARSISEQPGPLVFEGNGTDLTCSFADRLSADAWLDPHIGP
                     GKWVSVASFCEFSITAPSSSDWRGAFDIDGTAVASGLLVARDARVRPEGDERIRRAARL
                     REEIVARAPIELRLADGVLASVTAGGVDYTGAVIDVTNPGYAGHTLELGLGTNMNLLPL
                     VDWELNSQLNEGAGTLHLGFGEGMTGAHMDFVVAECGHRFQEGGAGAPR"
     gene            34660..34794
                     /locus_tag="ACTIVE_RS48405"
                     /old_locus_tag="ACTIVE_8864"
     CDS             34660..34794
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS48405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_8864"
                     /product="hypothetical protein"
                     /protein_id="WP_264159645.1"
                     /transl_table=11
                     /translation="MRELTINDQSWNVDEDDTLVEGAERLESADPVEAASLSYGYARI"
     gene            34874..36142
                     /locus_tag="ACTIVE_RS44235"
                     /old_locus_tag="ACTIVE_8865"
     CDS             34874..36142
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016777.4"
                     /locus_tag="ACTIVE_RS44235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8865"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_173100529.1"
                     /transl_table=11
                     /translation="MAERTRYTVISADCHGGADLLEYREHLDPAYQEEFDAWAASYEVP
                     YEDLKGEDGTRNWDSDRRLRELERDGTVAEVLFPNTIPPFFSASSLGSQRAAESAADLR
                     RRWAGLRAHNRWLAGFCAAAPGRRAGVFQVMLHDVGEAVAEIERAAAAGLRGGLLLPGT
                     PPGSGLPPLYYHEYYDPIWRACVEAGLPVNVHSGSAAPRAGDRPEDHVLFMLELRWWDQ
                     RTLRHLILGGVLERHPGLTVVFTEEGLGWIPNALRAMDGFVDSMRTASGRGDLSHGATV
                     ARNLSLRPSEYWRRQCYAGASFMHPSETAIRTSIGVSRIMWGSDYPHTEATYPYSESAI
                     RLAYAGVPEDEVELMLAGNAARVFGFDLEALARHAERVGPERDAVSAGVDPASLPAGVA
                     KSPAFAGITPGSSRTRWVDNRKA"
     gene            complement(36172..37014)
                     /locus_tag="ACTIVE_RS44240"
                     /old_locus_tag="ACTIVE_8866"
     CDS             complement(36172..37014)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012517.4"
                     /locus_tag="ACTIVE_RS44240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8866"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_173100530.1"
                     /transl_table=11
                     /translation="MTPTFGLYLPQVRRSFAQLATLAEAAEDLGFEAVWFMDHLALPGV
                     PGGALEGWTVATAIAARTSAVRVGHLVLCESFRNPVLLGRMAVTLDQISGGRLNLGLGW
                     GSSPSELTGLGFTADPPRVRRARLAELLDVLGLVVGGRPVDHAGEFFTVRDPQGGPAAV
                     QSRIPLTIGGVGEGTMALARERADWWNCWAPDTARLGELIPRTGTARVSANYEIAFSHR
                     ADVPDFVLTGPPRELARRLCADRDLGVRHFVVQMVDPAGGVRDLRRFMKEVAPAVTGG"
     gene            complement(37011..38246)
                     /locus_tag="ACTIVE_RS44245"
                     /old_locus_tag="ACTIVE_8867"
     CDS             complement(37011..38246)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014686.4"
                     /locus_tag="ACTIVE_RS44245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8867"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_173100531.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 3.1e-09, bitscore:
                     36.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDTRPLILVIGHGSELFRGHLLESVGADYRVHLFCRAEPTWERP
                     HICGSTVFDDVFDVPALIREAVRIAAAGEVRGVVSWSDDLAVPAAYVAESLDLPGGKPE
                     MVVACSDKHLTRAALAGANVPQPLSIAVSRTDEALRAAERTGYPAVLKPRGLAGSIGIV
                     RVDGPEELESWFPWSAGAHAAGAPRYETPVLVEEYLDGPEISIDSVVHRGRVQPIYLAR
                     KVVGYAPFFAELGHFVDGADPLLADLRVMQVLQAAHSALGFTEGVTFTEMRLTRRGPKV
                     IELNGRLGGDLLSLLGRYATGIDPGLVSAAAACGQPPVLAPDRKLTAGIRFFHPERDDT
                     TIRAIRFDEDGLPPEVVRAVTLAEPGETVSPPSRDIRYGRIAYAVAVSGSIDECGRVLD
                     EAERLLHVETGA"
     misc_feature    complement(38307..38321)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.89"
                     /tool="antismash"
     misc_feature    38311..38324
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.91"
                     /tool="antismash"
     gene            38363..39787
                     /locus_tag="ACTIVE_RS44250"
                     /old_locus_tag="ACTIVE_8868"
     CDS             38363..39787
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013584.4"
                     /locus_tag="ACTIVE_RS44250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8868"
                     /product="amidase"
                     /protein_id="WP_173100532.1"
                     /transl_table=11
                     /translation="MSHDFLDLDGVAQAGLLRTGRLSPAELVDAAIDRIERLDPVLGAL
                     AAERFERARDEAARPARGAFAGVPFLLKDAVQHSAGDRYQHGMTYLREHPWVSPADTAL
                     TGRYRAAGLVLLGRTKVPELTMSPTTEPLAHGPSRNPWDPTRSSGGSSGGSAVAVASGM
                     VAFAHGNDMGGSIRIPASCCGLVGLKPSRARMTLAPYASYWGPLTHEHVLTRTVRDSAA
                     VLDATAGPAPGDLTAAPPPSRPWTAELGADPGRLRIGLLQERPSGGPIAPECATAVNAT
                     ARMLESLGHHVRILAPGAFADADGVSAMGLVIATSVARDVTAWERRIGVPMHDLEPGTA
                     AAVARGSATTTAQLLDALDVLARWSRRIVRASSAVDVVLSPTLPGLPPPLGMLSGDRPL
                     SETAPAWTAMAELAVLSNISGQPAISLPLHRTETGLPIGIQLTAPYAREDLLFRLSSQL
                     ERTAPWPQTPSHLTRS"
     gene            39894..40646
                     /locus_tag="ACTIVE_RS44255"
                     /old_locus_tag="ACTIVE_8869"
     CDS             39894..40646
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF036686.4"
                     /locus_tag="ACTIVE_RS44255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8869"
                     /product="decarboxylase"
                     /protein_id="WP_173100533.1"
                     /transl_table=11
                     /translation="MRAPRIGLLYPTPDTGEDDFAALAARVTPRIDLDVIYMPWPDGVD
                     DLRELDTEATYDAVRRLGGEAHLRAVVPKALAAHDPIDAVAFGVSSASFLHGPDGVTAQ
                     VQTLSEVTGVPATSTTAAFLEALRHLRLRRVALASVYHPSGTEHFIDRVREAGTQVVHR
                     VDADAPSDRDLAAWTPDRITGLVRAAAHPDAQAILLPETALHTSPLASRLDSAAGVPVL
                     TATGVTIWAACRLLGLVPSADDAGPLFA"
     gene            complement(40895..43723)
                     /locus_tag="ACTIVE_RS44260"
                     /old_locus_tag="ACTIVE_8870"
     CDS             complement(40895..43723)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="ACTIVE_RS44260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8870"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_173100534.1"
                     /transl_table=11
                     /translation="MITSAARLVARREELALIDAAFRDSEAGEARFVLLGGDAGVGKTR
                     IMDHVAQRLADSGVRVLRGSCVALGAEGLPLAPVTAILRSLVRDLGTDALDAIVPGASL
                     LHRLLPDSGTAAEPSGQARMFESFTTLLERIGADRPLLLVIDDLHWADRSSRDLLGLLA
                     RSLRGTRVLVLLAFRTDTLGARHPLRAFTAELERLPSVRRVDVAPFNRAETAGLLAALT
                     GKRPPEALVDRVYQASGGNALFAAELARTSGTRLPTTLRDLLLERFSELADGAREVVRV
                     AAAGGPRVAHDLLAEVAGVAAPDLLAALRVAADAQILVADGDGYVFRHSLLYEAVAADL
                     LPAERVALHRAYAAALERDPGLTSPGRAAAETAYHWSEAGDAGRALPALLRAADAAEAM
                     DARAEQAQTLIRALGLWPRTGAPDRFAVVENALAAAGWSGEPLRALGLADRELVEETDP
                     GRAALLHAHRGLSLYSLGRDGSVTAFDEALQTIAGDEVAPAARAKVLDLAAAGLMLRGL
                     PDRAHAAATEAMHIASGLGDRDLLANASATAGTVLSQLGRYEEALAALEATGRPGSAPQ
                     QVRIDLNRSEALAALGRHDDAIAAARRGMHVCRTAGLTRTLGALLAFRIAAVLTVTGRW
                     DDATAEIAAALEQDPPGGAGGMLHALHGEIALARGDLDLARERLTLAQSLTGPASGFEA
                     VPADRLEARVALCDGRVTDARAALARALAAPVLTPAQSWALLVDGARIEARAGSRGATH
                     LPPNEGVPLPLAERAGQLPANGALCTAYAAEYAAVSGGSWTAAVAAWDTAGDPFAASGA
                     RLRAAEAAAASGDRDGARDLLRTAAAQASALGARPLAEEIALLARAAHIDLATGPASDA
                     SPAERLGLTGREREVLRLIAEGHSNRQIAETLFISPKTASVHVSRILAKLGAATRGEAA
                     ATAHRLRLFADR"
     gene            43845..44180
                     /locus_tag="ACTIVE_RS44265"
                     /old_locus_tag="ACTIVE_8871"
     CDS             43845..44180
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044751.1"
                     /locus_tag="ACTIVE_RS44265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8871"
                     /product="NAD(P)-binding protein"
                     /protein_id="WP_173100535.1"
                     /transl_table=11
                     /translation="MPGNRVTVLLAGAGATGLTCAAFLADQKVTCLLVERHPDQLTGRA
                     GTAWTQAAQTLDVTTHHLGIESLAAHGIGADGGLLVRPDGVVARRSTGKAPADLSKQAP
                     DPARSLA"
     gene            44177..44827
                     /locus_tag="ACTIVE_RS44270"
                     /old_locus_tag="ACTIVE_8872"
     CDS             44177..44827
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS44270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_8872"
                     /product="hypothetical protein"
                     /protein_id="WP_173100536.1"
                     /transl_table=11
                     /translation="MSPTEITAEGARAEHVVVAMAQQHDVAGLSFDNGASLLNVRTMDG
                     AGPLLRGRFTDPLPLVWAADANVHIEYPLGARLAHTSRPGELHLSARRPWSVDVHGGTD
                     RFDADLSGLRLSSLTFHSGLAHAHLRLGGPRGRRMIRFSSVTDLVLTRPVNVPVRVEAT
                     KGVSRLGLDDRSVDAANGFEGQTHDYNDADDRYLILLTGDVASLTITTAPELG"
     gene            45000..46538
                     /locus_tag="ACTIVE_RS44275"
                     /old_locus_tag="ACTIVE_8873"
     CDS             45000..46538
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891458.1"
                     /locus_tag="ACTIVE_RS44275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8873"
                     /product="multicopper oxidase domain-containing protein"
                     /protein_id="WP_173100537.1"
                     /transl_table=11
                     /translation="MTRDPSITRRRLLRATAVGVPALAAGSAGVPAWLWASADVSTVGR
                     TRFVNRLAIPPLATGRRDTDGARVYSLRAAAGTRRFKPGRPTRTWGFDNGHLGPTLRAM
                     RGETVRIDVRNTLRETTTVHWHGMHLPARMDGGPHQPIPPGGAWSPTWRIDQPATTLWY
                     HPHPHGATARHVYRGMAGLFIIDDPADRRLGLPARYGVDDIPVIVQDRKFDGDNQFDES
                     RPLIGGVGLIGDTLLVNGTIGPYHDVTTERVRLRLLNASNARTHRFALSAGRTFTLIGT
                     DGGLLPEPYETHTVQLTPGERAEVVVRLRPGERIVLRSMPPDLNVNFWNSRFEGGDDAF
                     DVLELRAAPRLAPSAAPPAALAPPPRLAPFGPGRVDRRFKLSGHKINERRMGMDRIDFR
                     IDRDRTEIWELRNTNGTPHTFHVHDTQFQVLSVNGAAPPPELRGWKDTVYARPGAPIRI
                     AVRFRGYADPNHPYMYHCHLLYHEDQGMMGQFLVTEPGRSPGPPPLTQDGHHHM"
     gene            46558..47445
                     /locus_tag="ACTIVE_RS44280"
                     /old_locus_tag="ACTIVE_8874"
     CDS             46558..47445
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS44280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_8874"
                     /product="hypothetical protein"
                     /protein_id="WP_173100538.1"
                     /transl_table=11
                     /translation="MRRTRIWGLVAAAVLCGSATSTPAKADPGSAPVIDITADDDGFTA
                     PASYTSGTTSFRVNTSATGDRGTIIGLARLRPGATPAGFADHLGKVFSDDPKVAVPAGR
                     ALMAEAELLGGAESQAGRSTTFTTMVRPGTYYLLNYLDFETRTPAGPQALHKLTITRER
                     HTGSAPRPGSVVGMTDTPSGPRFHLPDQIKAGAPLLLTNHLKQVNEAIFIPVSPDTSRA
                     EIQKFFEGVQNGEWGRPPFTGAPLGSPPLSPGRTLTLQAPLKPGRYAVITWVLDLTDGV
                     RLAAKGMHSLIIVT"
     misc_feature    complement(47924..47935)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.16"
                     /tool="antismash"
     gene            48146..48538
                     /locus_tag="ACTIVE_RS44285"
                     /old_locus_tag="ACTIVE_8875"
     CDS             48146..48538
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS44285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_8875"
                     /product="hypothetical protein"
                     /protein_id="WP_173100539.1"
                     /transl_table=11
                     /translation="MTAVIAAMLLLASIDVVRVLRGQGGVVSVTRIPAALSVLPSLLVW
                     CIGGLVAAFAWYFIDDCGTGAAAPCLDRPGATLSALSVICLVLPTLLLALVVRLGQRSA
                     VCAILAPPSIASIYILAIHLAVPHAG"
     misc_feature    48569..48582
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    complement(48670..48682)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.34"
                     /tool="antismash"
     misc_feature    48729..48744
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.19"
                     /tool="antismash"
     misc_feature    48835..48850
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.01"
                     /tool="antismash"
     gene            48842..49585
                     /locus_tag="ACTIVE_RS44290"
                     /old_locus_tag="ACTIVE_8876"
     CDS             48842..49585
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS44290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_8876"
                     /product="hypothetical protein"
                     /protein_id="WP_173100540.1"
                     /transl_table=11
                     /translation="MIIESALWPGDPAAYNALIIVIVALIVAGIVWTATYDHVRTKRLH
                     AHAAAFGWSPVGAADPMPGPVAEAVRSRRSKLAFATEQPYPIWLVWQQPSTDSTGQARE
                     LTRYFLLIGSEYPDVRVVRRTALGGLFKPVRGAGTGDPAFDRKFLIRGPGGHRAADLVT
                     PQVRAAMLAGDAPAWEITAGVLVASHPDAPTRRTLQPRADALTDLARMLTAPPLQRPDR
                     RVRHTPGTRFVSAISTDDSDHADGS"
     gene            49945..50391
                     /locus_tag="ACTIVE_RS44295"
     CDS             49945..50391
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS44295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_173100541.1"
                     /transl_table=11
                     /translation="MPIDEIAPVIDSTRVTAGKLPSRGREKHINCNTDTVPVTVSKLRS
                     NLGALPLNESLSGAGYRLRISPRRPMRSPRRSGRPSSEPYGNSSTGFACGCQAGALVIL
                     DQQAFWSCPTRRHERARVRSEKASARAGAHLQFDQPGQAARAQH"
     gene            complement(50388..50753)
                     /locus_tag="ACTIVE_RS44300"
                     /old_locus_tag="ACTIVE_8878"
     CDS             complement(50388..50753)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS44300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_8878"
                     /product="hypothetical protein"
                     /protein_id="WP_173100542.1"
                     /transl_table=11
                     /translation="MTETSMARTNRDLLICAWVCAVPAVGGFLLALGLMFLPPSFDNNG
                     SFQRPMSCGVPALFDREAFTKRQYGPDAGLDELGTSGCAATVAAREHQALGALAVATPL
                     GLLALTLHLHRRTAPAS"
ORIGIN
        1 gcatcactgc gacggaccag gtgccgtgtg tcttgttcca gttcagcgtc cggacgcctg
       61 gtcctgagga cgtcgctacc cagaacggct ggtgcgcggg tgcggatgcc gcgcgggcgg
      121 cgcccgggtg ccgggtgaag gccgcccgga acggagagag gttcgcggag gcgaactcgt
      181 cgtgcgcgac ggtgcgcagg taggcctcga cctcctgctt cggtccgatg ccgacgaaca
      241 gccgggtgcg cgggtcggcg gggcgcacca cgatccggac ctgcgccagt tcgcccacgt
      301 cgggatcggg gtccgccgga cgggccgtgt cggagccgac atcgatctcg tcggtcttca
      361 gggctgcggt cggcgtggtg aagcggtgct cggcggtgcc gaagcggccg ccggagtccg
      421 cctggagtgc gccgccggtg gtgagggcga cgccggccgg cacggcgacg gcggcggtga
      481 tggcgagcgc gatgcggacg gggcgcgagc ccgcggggag acgagccatg ctcttcctcc
      541 tttgagtagc acagtcgtgc tagtcgcaaa gtagcacgac tgtgctagaa aggggagatg
      601 gtgaaagtgg atcccgaacg gcgcagggcc gatgtggtgg aggcggtgtg gcgggtcgtc
      661 cgccgcgacg gtctgtcggc ggcctcggtc cgcaacgtgg cccaggaggc cggcctgtcg
      721 atggggtcgc tgcggcacta cttcgcgtcc caggcggagc tgctgtcctt caccttgcgt
      781 gcggtcatcg aacggatcga ggcgcggatc gcggcgctgc cgtcggaacc cgatccgcgc
      841 cgccgcgccg agcgcgtcct gctggaactg ctgccgctgg acccggaacg cgccgccgag
      901 aacgaggtgt ggctggcctt cacggcgcgc gcgcaggtgg accccgaact gcgagccgtc
      961 catgacgaag gctacgacgt cttgcggggc gggtgccgcc ggctggtcga ggggctcgcc
     1021 ggacatgtgg agggactgga cgtggaactc gagaccgacc gcctccacgc gctgctcgac
     1081 ggcctcgcgg tgcacatcgc catgcggccc gatgccctca cgcccgaccg ggcgaggctg
     1141 atcgtcgcac gccacctgga cgagctgaca cggtacgcgc gctaagtgcc tgcgtcacaa
     1201 cctcggagat cgtccctgtc gcccaacggg tagccgtttc gagtgcccct atgtatccgg
     1261 ttcctaaaac ggttataggg ggtgatcgcc gaaccggttc gcccaggagc gaggagagcc
     1321 gttcggacgg gcggcgccgt aacatcctgg cgaacgccaa ggcctccact cgcctctgtc
     1381 acaccgccgc tcacctgggc gaatggggca ctaagggtgc gcaccgatgg ggtcgcggtc
     1441 gatgtcgttg agagcttgga cgactgcaat agcggtggtg agcgtgcggc gagggcaggc
     1501 cgggcggtac ctggtcgttg ctcagtcggc ggggtcgtcg cggctgccga catcgggagg
     1561 gcctcgccga agaggtcaca agtttcgagc ggggcgttgc ccacgggcac ggtgtggtgt
     1621 ctacccggga aatgctggtt ccgtagagcc tccggtgtcc tcgtcgggtg ccaggcgcca
     1681 ggctgggttc ggcgctcagc ggtgtgccct ggtcccgttg cagggattgc agaggacacc
     1741 gcgtacccag ccgtgttcgt ggcggtggtc ccggacgtga cccgcccgcc actcgattca
     1801 gtcacgtata gccatgacac gtgcacggag ggttatagtt gcggtgtcgg cgcaatgcgc
     1861 gagaggcgcc gtggtctcag gcggggcaga tcatctggtc ccaatcctca tggcccaaac
     1921 ttcaaggagt cttcatgaag ctctcccctc gcccactgcg agccgccttg gcagcagcgt
     1981 caggtactgc cctgaccatg accgccttct cgagcccggc tcacgccgag ttcaagcgcg
     2041 tcccggaagt gtggcaggcg ggtgcggacg cctttgccgc tcctccctgt gggttcttcc
     2101 gctacagggt ccgtgagtcc gagttcgccg cgtacaacca ctgcggcccg acgacggtgc
     2161 ggatacacgt cgacgtcaga gggggcggta gcgcgaatga ctaccacctc tgtgtcagcc
     2221 ccggccgcac ccagctaccg ggcgcaggtc cgaactatct caacgcgtac tacatcggcg
     2281 gcgccggctg ccgaagcgga gagcgcaccg ggcacacccc ccactgagtc gatcaagctg
     2341 gcctcgcgtc gtgggagttg aacgggcgcc ggcccatcgt tcggtttcga cctggcagcg
     2401 gccgacgccg cctccgggca cgccccagcg caacacggtg gtcgagcgaa tcaccgaacg
     2461 catcctccgc ctcgctgcgg gccggctgag ggtggcgatc gacggattga ccgccgccgg
     2521 caagaccagc cttggcgcga actcgcagag caaatcggcg ctgccgggcg cccggtactc
     2581 agggcgccga ctccgcttct gagtaccttc ggccggcagc ctccgcatcg ggcgccgcgc
     2641 gtgagcggaa gcgccgggtt cgtgcggaca ctgcggacat ccggtcgacg cggaagcagc
     2701 gccagtcgtc gcgctcgagg ccgtaggcaa ggaggcacca gcgccggtcg gaggcgacca
     2761 ggcgataggg ctcgacctgc ctccgtcgta cctcgttccc ggacgggtag tcgaagtcgg
     2821 cccccacctc gtcgcggcag gctctgacca gcgtcaacaa cgcctcggcg gtgtcgaccg
     2881 gcgcacgctc tcggccaaag gactccaccg agccgggggc gggcgcactt cgtcccgcag
     2941 ccgggtgggc agcacccggt cgagtttggc cagcgcccgc agggcggcgt cactggcgct
     3001 ggcgaccgcg ctaacgagca gtgataccgc cgtggcaatc gcctcttcgt cattgagcag
     3061 caacggcggc aagacctgcc cccgcccaag ctggtagccg ccgccgacgc cctgggtggc
     3121 gtgcaccgga tagccgagcg tgcgcagccg ctcgacatca cgccgtaccg tccgcgccgt
     3181 gaccccgagc ctgtcggcca gctcggggcc ggtccattct cgacgctgct gcagcccgac
     3241 cagggtgagc acccgctccg tcgtaacccc gctcgtcaca ccgatgtcac ccgctccgtc
     3301 ggagatggcg gaccgatccc gtccgtcagg gaccgaagag ctcaacctcc gagagctccg
     3361 agcaactgac cgcctcgcct acgggcaaga tcgcggcgat gctgactcac atcccttgat
     3421 gacgttcgcg cgcatcagga acgtcccttt gggtcttcgg aagagcaagc acggccaacg
     3481 ccccggcggc tacgacgccg gcgcaggccc agaacgccat ggcgtaccca gaggtcggtg
     3541 cgccggtgcg ggctgcagcc aaggtggtca gcgcggccag gccgagcgag ccgccgacct
     3601 ggcgggagga attgaggatg ccggagatca gccctgcctc gccagggtcg gccccggccg
     3661 tggcggccat ggcgatcggt gcggaggtaa ggcccattcc gccggtgatg agcacgcccg
     3721 gcagcacgat gccggtgagc aggccgctgt ccggcgtgat cgtcgcctgc caggcgaaac
     3781 ccaccgctga gatcagcgtg cccgcggcaa gcagaggacg caggccggcc cggccgagca
     3841 gccgcggtgt ggccttggag gtcacgatga tggccaaggt gtgcggcagg aaggccaggc
     3901 ccgcctggag cgcgctgtag tgcagtacct gttgcatgta cagggacagg aagtaccaga
     3961 ccgcgaagcc cgcgacgccc agcaggaact gcacgaggag cgctccggac accgagcggg
     4021 cccggaagac cttcagcggc atcagcggcg cccgcgcgaa tgtggcctcc accaggacga
     4081 acgcggccag cgccagcaca cctacgccca tcaggatcag cgcgcgcgcc gaaccccagc
     4141 cgtacgcggg ggtctgcagc atcccgaact ccagcgccgg cagtcccaga gtcaccgtga
     4201 tcgcaccgat cagatcgggc ccgcgggtgc cgacaccgcg gctctcggcg agcaggcgca
     4261 gcgcggcgat gatcgcgacc acaccgatcg gcgcgttgat cagcaggatc caacgccacg
     4321 acaggtagtc ggtgagcagc ccccggcgag cgagcccacc gccccgcccg tcgccccgac
     4381 cgcgccccac gtggcgatgg ccctggcccg cgccgtctcg gtggggatcg ccgtcgtgag
     4441 gatcgtcagc gtggcggggg cgaccacggc cgcgccgagc ccctggctcg cgcgcgcggc
     4501 gatcagcagc tccggcgtgg tggcgagccc tccggccagg ccggcgatcg cgaacacggc
     4561 caggcccgcg acgaaggtgc gcctgcggcc gaacaggtcg gccgcgcgac ctcccagcag
     4621 caggaacccg gcgaatgtga ggacgtagcc gttgaccacc cattgcagcc tctcggcacc
     4681 caggtggagg cccgattcca tggcgggcag cgcgacgttg acgatcgaaa cgtcgaggac
     4741 catcatgaac tgcgctaggc agaccagacc gacgatcggc cagacgggac tgggcggccg
     4801 ggcgatgctc cgcccggacg gtggtgcatc ggcgacgttc atcatgatcc gagatctcat
     4861 taatggtggg ccatggcttc gtgatgggca gtcgctaggc gtcacgaacg cagcagtggt
     4921 gtcggatcac ggggcgatcc ggcaccgtga gccgcagcgg gtgcgggcca gcggctcgcc
     4981 cgcggggacg ggcttctggc gccttcggtc cggagcgcgc atgctgacgg atgacctccg
     5041 gggcgccgct gttggctcgc gcccagcgtc aaaccgtgcc ggtggactgc ccgcccctgg
     5101 gagtagcccc aacccccggg tcacacgacg gcgacggcgt cgatctcgac gaggaagccg
     5161 gggcccaagc cggccacgac gtggaccgtg atggcaggcg gcggatcggc ccggttccac
     5221 acctcctgga aggcggccac tccctcgtcg aacgagtgac catcgaccac ggcgatgcgc
     5281 cagtgcacga tgttcgccag gctcgccccc tcgctcttca gaatggtctc gaggttgcgg
     5341 aaggcctgcc tggcctgatc cccgaccgag ggaccgacga ccttgccgtc ggcgccgaca
     5401 ccgttctgcc cgccgacata gatcgtcttc gccggctgct cgaccacgac ggcctggctg
     5461 aaagccgggc tgcggtgaag cccctcggga ttgatgtgcc gtacgcccat gtgcttcctc
     5521 cttggatgtc gaaaccggtt ataggggttt cgttgcgaca ccagttatag tggtgtcatg
     5581 cgagcgaacg caaccggacg ggtgctgcac gaccccaagg gcgggtcgtt ccggttcgat
     5641 gccggcgccg tctgcctgga cttcgcccac acgggcggcg agggccggta cgcgatattc
     5701 gagagcctcc acgaacctgc cgacctcgct gagtggctgg cccagccgcc actggcggtg
     5761 gcaatgacgg ccgccgtgac cgcccgcgag ctgaccgcgg ccaaggccct gcgccaggcg
     5821 atctgggacg cggcccacgc ccgggcttcg ggccgcccgc ttcccgcgag cgcgatcgcg
     5881 accatcaacc gggcggccat cgcggcgcca ctgatccccg agctcgcggc cgacggcacc
     5941 accgccggat gggctccgcc ggtgcgggcc acgcaggcgc tgtcgacctt ggcgcgggag
     6001 atgatcgaac tgctggccgg gccgctcgcc gagcgcatcc gcgagtgcgc cggcgacaac
     6061 tgcccattgg tgttcgtcga cacctcccgc cccggcgccc gccgctggtg cgcgatggaa
     6121 cgctgcggaa accgccacaa gctccgtgcc ctgcgcgccc gccaggccat ggaaccgtga
     6181 cccggcctcc aacgcggcga accccagacg ccttggatca cccgcttgcc gccacagagc
     6241 aggcctcgat gccgacctca aaccgcacgg gccccgcgcg atcggcctgg ccgagccggc
     6301 cacgctacgg cgcctcctcg gcgagggcat gagcgtcgcc gaggccgcac gcacactgaa
     6361 ggtcggctgg gccaccgcct acgacgctct tcgccgtggc acggcacgac cctcgtcgtc
     6421 ctggcgaacc gagacccgcc cgagagtgct ttgaggcggc ttcgagtctc cgaccaccgt
     6481 gcatgatcgg tgacggcgca catgccttgt gtgagattgc gggttgggcg gcctggccgg
     6541 gggacaggcc acggggagcc cggcgcggac gggaagtagt ccgctcgcgc ggtgccggcg
     6601 gagttcttca gccgatgagc cgaaagagca cctcggcccc ctgaccaccg gcaacccttt
     6661 gctgctgctg ctgcgcgcgc cgagccgcgc cagtcctcgc ggacgcgcag gccgatcgcc
     6721 tggtggcccc cgcttgcgtc tccccgtgga tggccgacgg tgagagcaca gccgcccgca
     6781 ccaccatcgg caccggcgtc tggcccctgc caatccagcc cgcatccgcg agccgtcctg
     6841 ccccgaccgg gtgccaccag gaatcagctc cctcggacgc cctcccagac cgggacagcg
     6901 ccgccggctt caccgccggg accggctcgg tctccacccg cccagcgccc agccccgcga
     6961 tctcggcgac ccattgagtc tcggccccac gttccagcga gacgtggccc cgccaccgcg
     7021 aagcgaattg acgtacgcgt gagagttgac cccacccgcc tgatgactcc ggcgaacgat
     7081 cggtccatag gcgaatttcg cggaaaagtg ccagcatctt cggacgacct ggaaggggaa
     7141 cggcttgagt gagcccgcgg ttcggccgaa cgagatgacg gtgccgttga tgccgtgcgc
     7201 gtcagtggag gacgccttgg cgttctatga ggcgctgggg tttgaagcga cctacaagca
     7261 gagcaggccc tacgtgtacc tggcgctgca gtggagcggg ttccaactgc acttcggccc
     7321 ggcgcccaag gggctggacc cggcccggga ggagtcgggc gggtgcctgg tcatggtcga
     7381 cgccgtggcg ccatatcacg cggagttcgt cgcggccatg ctgccgggcg tacgggaagg
     7441 tgctgaggac cggcctaccg cgaatcaccc gctaccggcc cggcgcgtcc cggttcacgc
     7501 tgatcgatcc gtccggaaac tcgatcatct tcatccagcg cgacgagccg gctgagctgg
     7561 agtatggggg ctccaagaag ctggcgggcc tggccagggc gctcgacaac gcccggattc
     7621 tgcgcgagtt caaggacgat gacctgcagg cgttccgtag cgatccgcga agtccgccat
     7681 gggggtcgac ggagtgctcg ggcttgagga acgtctctgc gccaccgccc gggcaagtga
     7741 cggcaggccc cggaccgtgg ggcccttcgg ggccgggcgg gggcagggtg aggtcggctg
     7801 ctcgccggcc accttcagcc ggggcgtccg ggccgcgggg cgtacgcggc gacccgcgct
     7861 cgctggtcgg cgtcgctggc gcggatcgtc ccggccacgt actccggctt cggcggcacc
     7921 gtgaggtcgg tggcgatcag cttgggcgcg gtggcgtggc tggtcgtcgg cgtgtcagac
     7981 gatcggttcc tgggcggagg ccggggtggt ggtgatcagc gcggtgatct cgtcggcgag
     8041 gtgcgggccg agctcgcccc agccgtcctt gtagtcgtag acgctggcca gggtgcgggc
     8101 ctcgtagtcg ccgttcatga tctcgatgtc gttggcggtg atgagtgccg ggtgggcgac
     8161 gccgacggcc gaggagacct ttatcagctc cctgcgcagg gtccgcaggt agacggcggc
     8221 ccgggtggcc ttcgaggtcg ggtcgatacc gcgggcgagc cacgggttct gggtggcgat
     8281 gccggtgggg cacctgtccg tgtggcactt ctgcgactgg atgcagccga tcgacagcat
     8341 cgcctcacgg gccacgttga ccatgtcggc gcccagggcg aaggcgaccg tggcgttctc
     8401 gggcaggccg agcttgccgg agccgatgaa ggtcacctcg tcggtcagcc ccagttcggc
     8461 gaaggtgccg tagacgcggg agaagcccat gcggaacggc agcgccaccg agtcggcgaa
     8521 gatccgcggc gctgccccgg tgccgccctc accgccgtcg atggtcacga agtcgacacc
     8581 acggtcaccc cgcgccatca gcgtggccag ctcctgccag aaggccatct ctcccaccgc
     8641 gctcttgacc ccgaccggca gaccggtctc ggtggcgagc agttcgacga agtcgagcat
     8701 cgagtcgacg tcgctgaacg cggtgtgccg cgacggggag gcgcagtcct tgccggccgg
     8761 gatgccgcgg atctcggcga tctcctcggt caccttcgcg ccgggcagca tcccgcccag
     8821 ccctggcttg gcgccctggg agagcttgat ctcgatcgcc ttgaccgggg cgccggccac
     8881 cacgtccttg agcttgccga ggttgaagcc gccgtcctcg tcgcggcagc cgaagtacga
     8941 cgtaccgagc tgaaggacga ggtcgccgcc gttgcggtgg tacggcgaga ggcctccctc
     9001 gcccgtgttg tgcatcgtgc ccgccagcgc cgccccctgg ttgagcgccg tgatcgccgc
     9061 gccggacagc gatccgaagc tcatcgccga gatgttcacc acgctcgccg gccggaacgc
     9121 cttggcgcgc ccgcgcggcc cgcccagcac cttggcggag ggcagcgggg cctgcgggtc
     9181 gtgcacgtcg ggcagcgtgc cggcgaacgt gcgctgcttc acgtaggcgt gcccctggac
     9241 gtgctcgacg tccgtctcgg tcccgaaccc gaagtagttg ttctcctcct tcgccgacgc
     9301 gtagatccag gcgcgctggt cacgactgaa cgggcgctcc tcctcgttgg aggtcacgat
     9361 gtactgccgc agttcgggcc cgatcgtctc caacaggtac cgggcgtgcc cgaccaccgg
     9421 gaagttccgg agcagtgcgt gcttcttctg gatgaggtcg cgggcggcca ccagcgccag
     9481 tgctgttgcg gcggccgctc ctatgctccg ggcgcgcatg aacgttcctc ctcgatgcac
     9541 gactccatcg ccgggcaatg gacgtcgttg tgctgtcttg ggcgacgggc aatgggcgat
     9601 caggtgtcag cgtcggacaa agaacgcgaa atgatgttgc tcagcatagg gccggtcagc
     9661 gcgagttcgt cgagttcctc gagagcgcct ctggggacga gctgtgactc cgggccatcg
     9721 ctactggtct cgcgcgcggt cgtcgatgac gatgtggggg acgggcccag ctgcgatgga
     9781 gatccgcggg gcggtcgccc ggtcggcggc gttactgatc agaccgggat cggcctgcgg
     9841 ggaggatcgg aacggtggtt cgcggcagag cctccgacct gcgctgacgt ggacgctgga
     9901 ccggaccggg tcggcgcgct gtcgggtccg agtcgcagga ccagcgcaga tcggaggctt
     9961 accgctaatt cctaatgact acccacgggg cctcggtgga tggaggcgtt gggcgacgtc
    10021 ttcgccaatt ccgggcccgg gatcccaagt gcaggccgtg cggccgagcg cttacagccg
    10081 tctcacgaag gacccagcga ggtggcgttc agtcgccctt ggtccgtgtc gacggagtgg
    10141 actgccgggc aatgccgcct ctcacctgga tgaactgaac gcggtgtcgc cgcaccacgc
    10201 ttcacaccag gtgcgaccgg catcagcggt cggggactac gtccaggcgg gatcacggcc
    10261 ggtcaggccg aggatgcggt ccaaggtggg ggcgtcggcc ggcaccgcga cctccggtcc
    10321 gtacatgccc atctcccgcc cctgctccac cccggcgagg acggtgtcgt gcagatgctc
    10381 gagcaggtcg gcgggcagtt ccagccgctg cccggtcgcg actgccaggt cccagccgtg
    10441 cagggccagc tcgccggtga tcatgtcgcc caggacgggc gcgggcagag agtgcggcgt
    10501 gcccatgctc gtctcgccct cccaggcgct cggcggcgcc catgacgagg tgatgtcgtc
    10561 cagcagggcg agcaggcggc cgcgccagtc gccggtcgcc aggtccacat cggactcggc
    10621 gcccgccggc tgtggaacgg actccttgcg gccgccgccg gcgagggagg ggccccagaa
    10681 caggaggtgg ttgaccagtg cccgcacgtc gtattccgtg cacggagtct tgttggcgag
    10741 ctggtcgtcg gtgatggcgc gggcgacggc ggccatggcc tcggcggcgt tggacagatg
    10801 tgacatggcg gcgaggctag gcggcctgtg ccggaggggt attggacaaa ggcgacatag
    10861 gctttgccgt gtggagcggg acgttcgtga actgcggggt gcgtggagca ggtatcagcg
    10921 ccacacgttc cacgacccgt cgccggcgct cgcgccatgg gtggagcggt actgggaggc
    10981 tcgctgggac tacgccgagc cctaccggca gaagatcgtg ccgtacccga acgtgcacct
    11041 gtcgttcggc agtggccgcg cggacgtcaa cggcgtgtgc agcggttacc ggatcaaggt
    11101 cctcgagggc cgcgaccacg tcttcggcgt cgcgttccgg ccgggctgct tccgcccgtt
    11161 cctcggtgcg gccgtctcga cgatcaccga ccgcgtcgtc ccggcggccg aggtgttcgg
    11221 cccggacctg cccgcgacgc tcgacgtgcc gaccgtggag gcgttcctgc tggaacacct
    11281 gccggacgac gacccccgag tgcgccaggc ggtggcctcg gtcgagctga tcgcccaaga
    11341 caaggccgtg accagggtcg aacgcctcgc cgacgagctg ggcctgagcg tgcgggggct
    11401 gcaacggctg ttcgcggagt acgtcggcat cggacccaag tgggtgattc gccgctaccg
    11461 cctgcacgag gcgaccgaac gcatggccgc cggcggggcg atcgagtggg ccgcgctggc
    11521 ggccgacctc ggctacgtcg accagggcca cttcatccgc gacttcaagg gcatgttcgg
    11581 cgagcaaccg acctggtacg cgcagcggta ttagggcttc ggggcccgtt cgggccggac
    11641 cgtggccggc ctcttagtcc tcggcgcgct gctcgcggcc gaaccgggct ccgtgtcatg
    11701 gtccgggaca tgcagggcag tccgccaacg cgtcgtgaac caatgcaggc cagccggatc
    11761 cggccgcggt ctacccagac cagcgtcccc tcgcatccgc cccggacgac ggagacgggg
    11821 agccccatgg ccctggcggc gtccaagccg aggcccgccg gcgccgcagg cggtggttcg
    11881 ctcccgggag ccctcctctg aggagcgcgg gccggtgttc accgccggag gcgtggccaa
    11941 gccggggcgg gctctcctca gcggctgccg gcgtgccgct tgatctgggc ggacgacatc
    12001 tcaggggcgc gcggtgaggc cggcgggatc tccggggtgc cgaggccgta gtgcaccgcg
    12061 gcacgggtga ggtcggcctt gttgcggagg ccgagcttct gccggatgcg ctggacgtag
    12121 gtgtcgatgg tcgccttgga caggccgagc ttcgagctga tctgcttgtg cgtccagccc
    12181 tcggcgacca gggtcagcac ctgcccctcc cgctgggtga ggccgctctg caggacgacc
    12241 gaggcgggag cgggaggccc ggccggttca cagaagagtt ctccgccgac cgggccgaac
    12301 agtaagaagc ggtccggggc cacgatgctg agggcgagga tgagggtgcc ggcctcggtg
    12361 gtcatgtcca gatggccgtg cagcccggcg cggatcagcg tggccagccg gtcgcggtcg
    12421 agcatctggg agatgccgag caccagggag cgctccgtcc agcggcgcag gtcgtcgatg
    12481 aagcggtcgt cgatgatctg cgggagggcg agcagcagga tgggcggctc gcacgtttcc
    12541 tggaggagcg cgtccacttc gccggccgtc tggatcgcgg tcacgcggta gaactgcgag
    12601 gccgactcca atgcgctgag gacgcctctc atcagaagcg aaccgtcgtg caggaataac
    12661 acgagttgcg gggcgcggtc ggcgttggcg gcgtcgatga tttcgtgtac cgagggggag
    12721 cggatgtcgt ccggtctgtg tcccaagctc atcaatcctt caaggtgcga ggtctccgag
    12781 cgtctgtgcg aggtgcgctc cgagggcggc gggcgaatcg gtggcgcgcc cgccgttccc
    12841 gacctcgcgg tggtgcggat ctccttttcc gtgagccgcc cagccggccg catggcggcg
    12901 tgcgtccggg tcccccggtc cgggcagcga cgtgatggcg gtgttcaggg gcggcatcgg
    12961 ccggtattcg tactgggcga gaagccgata gtcggcgcgg aatgcgggct cgaagacctc
    13021 gcgcatatcg tcgatggcgg cgatctccgg cggtatgcgg ccctgggaga cgagccggcg
    13081 ccagaactcc gccgactcca gggccagcag ttcccgcggc gtgcggttga cgatgtcggg
    13141 cggcggatac gcccgcacga cgaggcggac gggcgcggga ccgccgagct cgcggacgcg
    13201 gtgcgccacc aggaaggcga gcagggctcc cgagcagtcg ccgaagaggg cgtacgggcg
    13261 ggacaggtgc gggagcagcg cgtcggccag ctcggccgtc aagggggcca gctccgtgcg
    13321 cgggggctcc ccgaacctgg cctcgcggcc cgggagggcc accgcccaga ggtcgatcca
    13381 gccgggcagc cgccgggcga ggccggtgaa gacgttgggc ccggcgcccg cattggggaa
    13441 ggcgaacagc cggatcgccg gttccgccgg atccccggtc aggcgcgtca gccagaggcc
    13501 gtccccggtc attcgcgatg gggggccgag cgtccgacga ccgccgagaa atcgccgagg
    13561 gtgggggcgt cgaagatgtc gaggatcgtg agcgaatggc ccaggcgctc gcggacccgg
    13621 gtgaggatcc gggccgccgt cagggagtcg ccgccgagct cgaagaacga ttcgtggtcg
    13681 ccgacggggc accccaggac ttcctcccag atggccctca gttccgcgtc ggtgtcgtcc
    13741 ggcgccattg cgaagcccgc catgccgtca cgtcctcccg gagtgatcaa caacttgtgt
    13801 gcatggtaag tgactccatc gcggtcttcc ttgtcaatca aatgagacgt tgctgttctt
    13861 ttggatggct cacttgtgag acatcggacc gtgcgacggg gcgcggacct ccgaagagtg
    13921 acttgtccgg cgcgacacgt ggttgatcga cttaccgtgt gagcaaggca ccgatcgtcc
    13981 gcctcgcgga ccgcgcccgg cggtgcgccg ggtgagcggc cgcgtcgcgg tcgcgctgac
    14041 ggacgtggcc aagcacttcc ggcagggccg gcggaccgtc gcccagcgga tccgccgggc
    14101 gcccgacacc cggcgggagg ttccggcgat cgacggcgtg gacctcgccg tccgcgaccg
    14161 cgaggtcttc ggcctggtcg ggccgaacgg cgccggcaag tcgaccaccg tgcgggtgat
    14221 cgcgacgctg ctggaaccga cccgcggcac cgtcgaggtg tgcggggtcg acgcggtagc
    14281 gcacccgcgg gaggcgcggc ggcacctcgg cgtggtgatc ggcggggagc gcagcgtcta
    14341 ctggaagctg accggccggg agaacctgga gtacttcgcg gcgctgtacc acctgccgcc
    14401 ccgcgagacg ccgggccgga tcgagcgggt gctgcgcgac gtggagctgc tggaccgcgc
    14461 cgacgactac gccgagcgct actcgacggg catgcggcag cgcctgtcgc tggcgcgcgc
    14521 gctgctccag gagccggccg tgctgctgct ggacgagccg acgtccggcc tggacccgcg
    14581 ctcggccgag cggctccgcg agcaggtccg ccggctgagg gacgccgggc actgcgtgct
    14641 gatcaccacg cacgacatgg cggaggccga ccaggtctgc gaccgggtcg ccgtcatcga
    14701 ccggggccgc gtcgcccggc tcggcacccc ggccgagctg aagcggctgg tcaaggccaa
    14761 ccaggtcgcc cgggtccggc tcgtcctgcg ggaccgggcc ggtgacagcg acctgctgga
    14821 gtcggtcggc cggttcgcga cggtggcgga caagtccgtc gacgggctcc acgccgagat
    14881 gaccctgcac ctggcaccgg gcgtggacct cctgccgcgg ctggtggagg cggccaaccg
    14941 gcacggcgcg acgatccacg gcgtggacgt cgagccggtg acgctgcacg acgtcttcct
    15001 cgcggtcacc gccccgggga cggccggatg aaccgggcgg aggccgagct gcgcgcgatc
    15061 gccgcgacga cccgcaagga gttgcggctg atgcgccgct atcccgcgga gatcgtggcg
    15121 ctggccgtct ggatgctgct gctgccgctc gcgtacatcg cccaggcgag ggccttcagc
    15181 ggcggcggcc cggcgtccgt cgccgcgttc gagcgccggg cgggcaccga cgactacgtc
    15241 gccttcctgt atctcggctg gtccgtctac ctgtggatca cagcggtcct gtgggggccg
    15301 ggcctcgcgc ttcggcagga gcggcagcga ggctccttcg agaccatgtt cgccagcccg
    15361 gcgtcccggt tcaccctgct gttcggcggc gctcccgcgc agatcgtccc cgtgctggtg
    15421 gtgttcgcga gcgccgccgc gtcgatgcgg ctgctgttcg gcgtgccgct ggacggcggg
    15481 gacctcgtcc gctggctcgc cgtgctcgcg ctcgccttcc cggtgctgat ggcgctcggc
    15541 gcggtgttcg ccacggcctc gctgtcgctg caggacgcgt ccggcgccct gcagatctcg
    15601 cggggggcgt tcactctcct gtgcggggtg acgtacccgc tcgccgtcct gccggagccg
    15661 ctgcgcgccg tgggggaggc gttgccgccg acacaggtgc tggacgcact gcgcgccgtg
    15721 acggccgggc acgaggggct cgcggcccgg cttcccgggc tggcggtcct gctcggcgag
    15781 gccgtcgtcg ccgccgcgct ggccatggcg ctgctctggc tgagcgtccg gcacgcgcgc
    15841 agggcgggga agctggggct cttctgatgg ccgggacgac ggggcgggag ggcccgctga
    15901 cgtggtacca ggaggccgtc tggtggagcc agtactggaa cccgccggac gagacctacc
    15961 cgccgatggc ggacgtctgg tacctgccgg agcgcccccc ggcggaggcg gtgcacgcgg
    16021 tgttcgcgga gctcgcggcc cggcacgagg tcctgcgcac cagcctgccg ctgggggagg
    16081 acggcctgcc ccaccagcgg ctccacgcgc ccggtgcgat gccggtgccg ctccgttccg
    16141 tccccttggg cgagctccgt gaggacgtgg ccggagtgct cggcggcttc cgccgtccgg
    16201 gcgccggcga tccggacggt ccgcgctggc gggcggtgct cggcgtgaag gaagggcggg
    16261 ttccggccgt cgcgttcgcc ggcgaccggt cggtcatgga cggcggggcc gtcgccggac
    16321 tgcgccacca gttcctgacc gcgctccgcg gccgccgcgg cgttccaccg ggcgcgctcg
    16381 tgcagccgct cgcccgcgcg gaccatgagc gctccgccgc gggacgggcc aaggccgacg
    16441 cggcgctcgg ccgtctcgcc gacgtgttcg gccgggctcc gggcccgctt ttcaccggcc
    16501 cgccggcgcc gcccggcacg ccgcggtacg tggaggcgtc gacgcgctcg ccggaactgg
    16561 cggcccgcgc cgcgcaggcc gcccggatcc accgggtgac gctgccgagc atcgtgctcg
    16621 cggccttctc atcggtgctg gccctgcgca cgggacggtc cgtcgtgccc atccggagcc
    16681 tgtgcgcgaa ccggacgacg ggggccgagc gcgcgagcgt cctcgggctc taccagccgg
    16741 cctacctggt cctcgacctg tccggggacc cgctcatgtc ggacgtggtg cggcggacgt
    16801 ggcgggagtc cctcagcgcc tacgcgcact ccgaataccc gcctgacgag ttccgcgaga
    16861 ccgtggtgcg cgccgcgcgc gggcgcgggt tcgtgccgga gttccagctc gactacgact
    16921 tcctacccgc acccggtccc gccacgggac gtcccccggc gggaggggcg gtggaaaacg
    16981 cggaaccgcc cgtcgagcac gccggcagcg accagggccg ccccgattac gccctgttcc
    17041 aggcgcgggt gctcggcgag gagttgatgc tcgcgctcga cgccgacacc gcgctcgttc
    17101 cccgcgccga gatcgaccgg ctgctgtcct ggacggtgcg cgcgctgttc cgcctggcag
    17161 acgcgtccgc cggcgccatg cgctgcggtg agttcggcgc ggcgatcgga ctggagccga
    17221 aggccgcgga gggggcgcag gagccgcctg tcgcggccgg cgcggcggcg gacccggcgg
    17281 ccgaacgggc cttacgcgag gcgttcctga ccgcgcacag gggagtgggc gacgtggatc
    17341 tccgcgatga ctacgtggcg gccggcggac ggctgcgcag agtgccccgc acggtgcgcg
    17401 cgctcgccgg tcacggcttc ggcgggctgc gggccgagca cgtcgagacg ccggtgagcc
    17461 tccggacggt cgcggccgcc ctgcggcgcg agccgtgcga ggccgggcga tgacgggcgg
    17521 cgccgtcccg gcggccgagc ggttccgcga gctggcgcgt gaccgcccgg acaagcccgc
    17581 gctgatcgtg gacggcgggc ccgccgcgcc ggacacggtg gtgagccggg aggcgctgga
    17641 cgccgcttcg gcggacctcg ccgcgcggct ggcggcctcg gccgccgcga ccccgcggcc
    17701 gcccgtggtg gtgatcgacg cggcgaacga cgcgcggacc gtgatcgcgt tcgcggcctg
    17761 catgcgcgcg cggctgccgt tcctgcccct ggacccgctg atgccggagg cggaggcggc
    17821 gcgggtgctg gacgcgctgt ccgcgcaccg gtccccggtg gccgtggagg acaccgcctc
    17881 cccagcgggg aggccccacg ccgcgacggg ccggggaggg tacctgctgg ccacgggcgg
    17941 ctcgtccggg acgcctcgcc tgatcgagca tccgcgcccg ctcgaccacg acccggcacg
    18001 ggtgccgaac gcgatgctgc gggccgtggg gtggcgcagc gggcagcgcc agctcatcgc
    18061 ggggccgctg caccacgccg cgccgttcat gtgctgctgg gagggcctgc tcggcggcga
    18121 cacgctggtg gtgctgccgc gcttcgaccc gcgccggatg ctccgcgcca tcgacgagca
    18181 cgcgatcgag tgggcgcagc tcacgcccgt ccacctccag tggggcctgg cggcgctgga
    18241 gcggtccgcg tactcgctgc gctcgctcaa cgcggtgatg cacaccgccg cgccctgtcc
    18301 cgccgaggtc aagcgcgcct ggatcgacct gctcggcccg acgcgcctct acgaggtcta
    18361 cggggccacc gaggcggtcg ggaccacgct gctgcgcggc gacgagtggc tggagcggcc
    18421 gggcagcgtc ggccggggct tctgcacgca gatccgcatc gtcgacgagg acggacggct
    18481 cgtcccgccc ggcgtcgagg gcgaggtgct catgcgccgc accaccggcc gggacgcggt
    18541 gggccgggag ctcggcggcg cgtccggcgg cgtccgctgg acggtcgacg gcttcgccgg
    18601 cgtcggcgac gtcggccgtc tcgacgccag cgggcacctg tacctggcgg cccgccgcca
    18661 cgacatggtg atcgtcggcg gcggcaacgt ctatcccgcc gaggtcgagg cggcgctcgc
    18721 cgagcatccc gacatcctcg acgtcgcggc cgtgggccgg gccgacgggc agctcggcgg
    18781 ggggctgctc gccctggtga tcaagcgtcc gggcagcgcg ctcaccgagg ccgccgtggc
    18841 ggacttcgcg cgcggccgcc tcgccccgca caaggtgccg tggaccgtgc ggttcgtgac
    18901 ggagctgccg cgcacggagg cgggcaagct gcaccggcgc cgcctcgccg aacaggaggt
    18961 gacgggtgtc tgatctcgac gacggagccg gcgggccggc ggatgccggg ggccgtcccc
    19021 ccgcgggagg caccgacacg gtcgtcccgg ggctcgggac gcgacgggtc gaaggggtcc
    19081 tgcgggccca tccggacgtg cgcgaggcgg tcctgctgcc gagcggcggc gacggcccgg
    19141 gagagacggc gctggtggtg ccgcacgggt acgccgtcgg acccgagctg gccgcgcacg
    19201 tggccgcgga gctcgggatc gcggcgatcc cggcgaccat cgcgctgctg ccggagatcc
    19261 cccgcggccc ggacgggacg cccgacgcgg cggcggtccg cgagcggctg gcctcctggc
    19321 ccgccgtgta ccgcttcgag ctgccgcgca cctccgccga gcggcgcgtc gccgccctgt
    19381 ggtgccgggt cctcgaccgc gggtgggtcg gcgtgcacga cgacttcatc gagctcggcg
    19441 gcgactcccg gacggccgcg ctgctcctgg ccgagctgcg cgcggagccg ggcgcggacg
    19501 tcaccatggg ggacctgttc gagctcgcca ccgtggcgcg actcgccgag cggttcgggc
    19561 cctccgatga ctgaggcgcc ggccggggga cgcccgtccg gggacgatct cgccgcggag
    19621 ctgcgccggc acgccgcccg gctgcttccg gcggccatgg tccccagcct gatcgtggag
    19681 cttccggagc tgccgaggac gccgagcggc aagctcgacc gcgcggccct cccggcgccg
    19741 gacgccgctc ggggccccgt gcgggccgag ccgggcgacg agcgggaggc ggcgctcgcg
    19801 gagatcttcg cggaggtgct ggggctcccg gcggtcggcg cggacgacga cttcttccgc
    19861 ctcggcggca cctccgtgca cgcggtccgc gcgctggccg gcatgtcggc gcgtttcggg
    19921 acccgtgtcc cgccgctgcg gttcttccag gagcccaccg tccggcggct cgcgcgcgtc
    19981 ctgagggaag ggggcggctc gtgacatcgg acgcccggga ggcggcgccg gcggcgagcg
    20041 cgtacgcgcc gccgcccgtc caggagacga tgtggctgcg cgaacggctg ctgccgggca
    20101 ccgcgatgca caacctggcc gcggcgcacg agatcgacgg gcccgtggac gccgccgtcc
    20161 tggccgcggc ggtccggacg gtcgcggccc ggcacgaggc gctgcgcacc acgtttcacg
    20221 aggtggcggg gcggccggag gcgcgggtcc acgcggacgc gccggtcgag ctggcggagg
    20281 tggacgcgac cggccgcgcg gactggcgcg acccggcgag ggccgaggcg acccggccct
    20341 tcgacctgac ccgcccgccg ctgctgcgcg cgctgctctt ccggcggccg gcgggccgct
    20401 cggcgctcgt gctggtcgtc caccacctgg tggccgacgc ctggtcgctc gggatcctgt
    20461 gggaggagat aggggacgcc tacaacgccg gcctgcgcgg cgaaccgtgg atgcctccac
    20521 cgccgcccct ctcctacggc gaccacgcgc ggcgcgagaa cgcggcgcgc ggcgccggcc
    20581 gccgcgaccg gacggcggcc ttctggcgcg accggctggc gacggcgccg ccgttcaccg
    20641 tcgtgccgcc ggaccggccg cgcccggcgg gcgcggcgac cggcggcgcc acgcacgagg
    20701 tccggctcga cgccgggctg cgggaccggc tggcggcgtt cgcgagcgcg cggcgcgcgt
    20761 cgccgttcat ggtgctcgcc gccgtgtgga gcgccgtcct cgccaggtac gccgggcagg
    20821 acgacgtggt gttcggcgtt cccgcgtccg ggcgggaccg gccggacctg gagcgcgtcg
    20881 tcggcctgtt cgcgagcccg ttcccgctgc gggcggccgt ggacgtcgcg gagccgttcg
    20941 aggcgctgct cgcgcgggtg cggcgggagc tgctcgaatc gatggcccac caggacgtgt
    21001 cgatgctgga gctggcggac gcggcccggg cgccgcggca gctggacacg acaccggtgt
    21061 tccagatcct gttcacgctg ttccggacgg accaccggcc gctggagctg gcgggcgccc
    21121 gctgccgcta cgtgtcgggg ctcgtggagg cggtgcagac cgacctggcg ctgacggcga
    21181 cgatgccgaa cacgggggag ttgcggttcc agttgcacta cagcaccggc ctctacgacg
    21241 cggagaccgc gcggtgcctg ctgggatgcg tcggcgaact gctccgcgac gccctcgaac
    21301 gccccggcgt gccgcttcgc gaactgcgca tgaccggcgg atccccggcc ccggccgctg
    21361 tgcggcccgc cgcggatgcc gcaggaggcg agacggcacc ggagatggtg cgccgcgtgg
    21421 cggcggccgt acccggagcc gtcgcggtct ccgacgggac gcgttcgctg acgtacgccg
    21481 agctggagcg gcgggtcgag cggttcgccg ggcggctgcg cgcggcgggc gccgggcgcg
    21541 gtgatctggt ggcgctcctc ctgccccgcg gcgccgacct ggtcgtcgcg atgctcggcg
    21601 cgtggcgggc gggcgccgcc tacctcccgc tcgaccccgc gcatccgccg gaccgtctcg
    21661 cgtccctgct ggccgacgcg aggccggcgg tcgccgtggg ttcctccgcg tccggcgcgc
    21721 ccgtgccctc cggcctgccg gtgctgccca tggaccggga cggcgggcag gccaccgcgt
    21781 ccgccgggcc cccgcacgac cccgcacccg gtgacctggc gtacgtcatc cacacgtccg
    21841 ggtcgaccgg cgggccgaag ggcgtggagg tgccccaccg ggccgtcgcg cacctgttcc
    21901 gggcgatggc ccggcgcccc ggcctggacc ggaccgacgc cgtcctcgcg ctgacgaacc
    21961 cgacgttcga catctcgctc gccgagttgg tcctcccgct cagcgtgggc gcccgcgtcg
    22021 tcatcgcgcc cccgggcgcc gagcacgacc cgcgggccgt cgccgggctc gtccgggaca
    22081 cggaggtgac caccgtccag gcgacgccga ccggctggcg gaacctgctg ctcgccgccc
    22141 cggcgggccg gtggctgcgg cgcgcctggt gcggcggcga ggcgctggac gccgcgctgg
    22201 ccgaccgcct caccggcctg gccggcgagg cgtggaacct gtacgggccg accgagacca
    22261 cggtgtggtc gctcgccgca cggctgcggc ccggcgccgg gaccgtcccg ctcggcaccc
    22321 ccctcgggga cacgaccgcg accgtccgcg acggatggct cgaacccgcc ccgcccggcg
    22381 tcgcgggcga gctgtggatc gggggaccgg gcgtcgcgcg ggcgtaccgg gaccggcccg
    22441 ccctcaccgc ggaacggttc gtgccggacg ccggtggcgc ggtgacgtac cggaccggcg
    22501 acctcgtgcg gcgccgcccc ggcggcgggc tggagtacct cggccggacg gaccggcagg
    22561 tcaagctgaa cggccaccgg atcgagccgg gcgaggtgga ggcggtgctc cgcgcgcatc
    22621 ccgcgatcgc cgacgcggcc gtcgtcctgc gcgacgacct tccgggcggg ccccggctcg
    22681 tcgcgtacgt cacccgtcgt cccggagggg gtgcgccgtg agcggcggct ccctgtactc
    22741 gtggttcgcc gcgggcgccg cgcgccaccc ggacgccgtc gccttggaga cggggaacgc
    22801 gagctggacc tatgccgagc tggagcgggc cgcggccgcg accgccgcgc tcatggcacc
    22861 gcggcgcggc gagccgcccc ggcgggtcgg cctgctctgc tcccgtacgc tgcccgccta
    22921 cgccggctac ctggcggcgc tgcgccttgg cgccgccgtc gtgccgctcg cccccgggta
    22981 tccggcgccc cgtaaccggg ccatggccga ggccacgggg atcgacgtgc tgctcacgga
    23041 cgagttcgag gccgcgcggg cggccggcat cgcggcggcg gcgggggcga gggtcgtcga
    23101 gctgcccggc tcaccgcggg gcctcgcgca gacctcctcg ccgcccgcgc ccgcctccgt
    23161 ggagccggac gacatcgcct acatcctgtt cacctccggg tcgacgggcg tgccgaaggg
    23221 cgtgcccgtc acgcacgcca acgtcaccgc cttcctgcgc tcgtgcgccg agcggtaccc
    23281 ggtcgtgaag ggcgaccggg cgtcgcacac cttcgagctg accttcgacc cctccgtctg
    23341 cgacctgttc ctggcctgga gcgggggcgc gaccgtcgtc gtcccggtgg ggaacgaggc
    23401 gctgcggccg tcggcgtacg tgaaccgcag gggcatcacg cactggttct cggtgccgta
    23461 cgcggtgtcc ctcggcctgc gggccggggg agtggagccg ggctccatgc ccggcctgcg
    23521 gcgcacccgc ttcggcggcg accggctgac cgcacggcag gcggccgcct gggccgaggc
    23581 cgcgccgcac agcgccatcg agaacaccta cgggcccacc gaggcggcgg tgttctccac
    23641 ggcctacgaa ctgccgcggt ctccgtcgaa ctggcccgcc acctccaacg gcaccgtgcc
    23701 gatcggccgc ccgctgccga cggtggagca cgtcgtcatc ggccctgacg ggcggccggc
    23761 ggcggagggc gaactatgcc tgcgcggcga gcagcgcttc cccggctacc tcgacccaag
    23821 gtccgacgcc gggcgcttct acgcccttcc gccggcggcg cccgcccggg tgccgtgccg
    23881 gccgggcccc tacgggcccg agcactggta ccgcaccggc gaccgggtgc gcgtcgagga
    23941 cggcctgctc gtccacctcg gccggctcga ccagcaggtc aaggtgcgcg gctaccgcgt
    24001 cgagccgggc gaggtcgagg cggtgctgcg gcggcacccg gacgtcgccg acgccgtcgt
    24061 cttcccggcc ggggacggag acgggcgcgg cctcgcggcg gtctacaccg gccgcccggt
    24121 gccggcggcg gacctggcgg cggcggtcct cggcgccctg cccccgcaca tgctgccggg
    24181 ctcgttcgag caccgggcgg tgctgcccgt caacggcaac gggaaggtcg accgggcccg
    24241 cgccgcggcg gagggcgccg gcgccccgtg gccgccgggg acgccgcacg cggccccgtg
    24301 aaaaggatcg gacagcgagg agccaccatg atcggcaccc tgaccacgct cgaacactgc
    24361 cttcccggcg actacgaacg cctcgccaag tggttctcct cggcgtccgg atggtacgcc
    24421 ctcggaaagc agaaactgtt ctccgcggac gacctgagga acgagaacct gcacgggagg
    24481 acgcacttcc tcatcgtggt ggagaacggc agcaagcggc gggtcggcgc ggtcacctgg
    24541 acggagaagg aggagtacga gggcagctat gtgatcggca ccggtgtcgg agatcccgaa
    24601 ctctacgatc ggggactcgg tgcggaggcc accgtcctgc tgctcaacta tctcttccac
    24661 atgaagaacg cgcaccggat cgaattcatc ttcggcctgt acaacaagca tgcgcttccc
    24721 gcgctgacgc agtggaacgt cacgctcgaa gggatcctgc gcgactactt ctatctcgac
    24781 ggcgagtacc aggacgccgc gctgtgctcg gtgctgcgtg aggagttcta cgagttcgcc
    24841 gccgcgggcg gattcctgtc gaccctcgac gagattccgc gcgccgacaa ggaggaggcg
    24901 cgggcacggg tgagcgagca tctcgcgaaa atgccggacc gccatctcgc ggacctgttc
    24961 ggacggtccc gcccggtggc cccgcaccgc cgggaacggc cgctctgacc agcggcgaca
    25021 agggtcagac cgtcaaaaag agactgtccg gacgccgccg gacgtggtgg tatcgggatc
    25081 atcgtccacg gaaggaacgc cgagcgtgca cgaggtggag tcggcgatgc tgggcatcgt
    25141 ccgggacgcc tgggagaaac gcctgggaaa gcgcggcctc ggcgtcgagg tgaacttctt
    25201 cgacttcggc gggacgtcgc ggatcatcgc cgaggtgcgc gccgacctca tggcgggact
    25261 cggacgcgag atacccctcg tggcgttcta ccgccatcag aacatcagag ctctggcccg
    25321 ccatctggcc ggcggcgccg acgcctcccc ggaggcaggg agagcgcgcc ggcccgcgcc
    25381 gggcgggcgg cagcgggcac tgcgcggcgc ggcacgcgcc cgccggacgg aaggtgaagc
    25441 gtaaatggcc gacgacattc gggagaacga tgtcgcgata gtcgggatgg cgtgccgctt
    25501 tcccggcgcg aacgacgtcc gcgaatactg ggacaacctc gtcaagggcg tcgaggccat
    25561 ccgcttcctg accgacgacg agctgcgcgc cgccggcgtt ccggagcgtt tcgtcaacga
    25621 cccgaactat gtcaaggcct gtccgatgat cgacgacatg gacgggttcg acgcggcgtt
    25681 cttcggctac accgcgcgcg acgccgaact ccgcgacccc cagggccggc tgttcctgga
    25741 gacctgccac agcgcgctgg aggacgccgg atacgacgtc ggccgctact ccgggaccgt
    25801 cggcgtgttc ggcggggcgg gggagtaccg gtacggctcg gacaacgtgc ggcgcaacgg
    25861 cgcggccgtg gacgccgccg gcgggatgag cgtcgcgacg gccaccgagc ccgactacct
    25921 ggccaccacc gtctcctacc ggctcgggct ccaggggccg agcttcaccg tccagaccgc
    25981 gtgctccacc gcgctggtgg cgatccacct cggctgccag tcgctgcaga tgggcgagtg
    26041 cgacatggcc ctggtcggcg ccgtggacgt ccgcctgccg tacgggcgcg gccactggcg
    26101 ggtcgacggc gggatcggct cggcggacgg gcacgtccgg gccttcgacg cggccgcgtc
    26161 cgggaccatc ttcggcagcg gggtcggggt gctggcggtg aagcggctcg cggacgcccg
    26221 ggccgacggc gaccacgtgt acgcggtcat ccgcggctcg gcgatcaaca acgacggcgc
    26281 cgcccgcgcc gggtacaccg ccccgggcgt cgaggggcag acccggctga tcgtggaggc
    26341 gctggcggtc gcgcaggtgc cgccggagac gatcgggtac gtcgaggcgc acggcaccgg
    26401 caccctcgtc ggcgacccga tcgaggtgac ggcgctcagc gacgcgttcc gcgcggctgg
    26461 ggcgaccgcc gcgcagtact gcgcgctcgg ctcggtgaag accaacgtgg ggcacctcgg
    26521 cgcggcggcg ggcgtcgccg ggatcatcaa ggcctgcctg gcggtccggc acggcgtgat
    26581 cccgccgacg ctgcacttcc aggagccgaa cccggcgatc gacttcgagt ccagcccgtt
    26641 ctacgtcaac accgagccgg tgccgtggac gggaccgcgg cgcgccgggg tgagctcgtt
    26701 cggcatcggc ggcaccaacg cgcacatcgt cctggaggag ccgccggagc acgtacgggt
    26761 ccccgatgag cgctcgtcgc cgcaggtcat cgcgctttcg gcgcgcacgg gcggcgccct
    26821 cgccgcgatg gccgcgcggc tcggcgagca cctcggggag ccggatccgc cgcccctcgc
    26881 cgacgtggcg tggacgctgc agcacggccg ccgcgagttc ccgtaccgcc gcaccgtggt
    26941 ggcggcgacc gtgcaggacg ccgccgcggc cctgcgggac ctggccggcg cggcggcctc
    27001 cacccggccc gtcccggtgg acgggcgcgg cgtggcgctg ctcttccccg gccagggcgc
    27061 ccagtacccg ggcatggggg agggcctcta ccggacccag aaggcgttcc gcaccgtgat
    27121 cgacgactgc gccgaggtgc tggagcccct catcggcgcc gacctgcgcg acctgctgta
    27181 cggaggcgcg ccggacgagg cgctcgcgcg gacccggctc gcccagcccg ccctcttcgc
    27241 cgtcgagtac gcggtggcgc ggctgttcgc ctcctgggga gtggtgccgg acgcgctgct
    27301 cgggcacagc atcggcgagt acacggccgc ctgcctcgcg ggcgtgatgt ccttcgagga
    27361 cgccctcgcg gtcgtcgcgg cgcggggcga gctgatgcag ggcatgccgc cgggctccat
    27421 ggcggcggtg ccgctgcccg agcacctggt cgtcccgatg ctcctcggcg gcgtcgaggt
    27481 ggccgcggtc aacggccccg ccgcgaccgt cgtcgccggc cccgacgccg ccgtggacgc
    27541 cttcgagaag cgcctcgcgc cgtggggcgt gcgctgcggc cggctggtca cctcgcacgc
    27601 gttccacagc ggcatgatgg acgcgatcgt cgagccgttc cgggaacgcg tcgcgagcgt
    27661 gcggctgaac gagccgcgga tccccttcct gtccaacgtc accggcacct ggatcaccgc
    27721 cgagcaggcc accgatcccg gctactgggc cgcgcacctg cgcagtgccg tccgcttcgc
    27781 cgactgcgtg cgggccctcg ccgacggggc ggaccgcgtc ctgctggaag cgggccccgg
    27841 ccgcaccctc accggcgcgg cgcggcagtg cctccccggc gcccggaccg tcctcgccac
    27901 ctcgatgcgg cacccgctcg gcgagggcga cgacgaggtc ctcgccctgg aggccctcgg
    27961 caggctctgg agcgccggcg tccccgtggg ctgggacggc gccgcgagcg gcgaccgccg
    28021 ccgcgtgccg ctgccggtct acccgttcga gcggcgccgg tactggctgg accccgaccc
    28081 cgccggaacc gccggccagg acgcggagga gcacgacgag ggcgcccgcc cggtcgagcg
    28141 cgccgtgtac gcgcccgtct ggacggaacg cccgatcggg accgagatcc cggcggtgcc
    28201 ggacggctcc cggtggctgg tgctgacccc cggcaccggg ccggtggagg atctcgcgga
    28261 ccggctggag gccgaggggg cgcgcgtcgt ccgcgtgacc gccgggcccg ggttcgccga
    28321 gaccggcgcg gaccggttcg cggtgcggcc cgccgaacgc gacgactacg aggccctgct
    28381 cggcgcgctc ggcgacggcg cgttccccac ccatgtcgtg cacggctgga cggccaccgc
    28441 cgccgaaccc gacccgctcg cccccgaggc cgtcgagcgg gcctgcgacc tcggcttcta
    28501 ctcgctgctc ctgctggcgc aggcgctgga ggaccggctc ccggacgagc ccgtccggat
    28561 cgtcgcggtc agcaccaaca tgcaggacgt ctccggcgag ggcgccaacg agcccggcaa
    28621 ggcgacgctg ctcggccccg ccatcctgat gaaccgcgag ctgcggcacg tcggctgccg
    28681 cagcgtggac ctcgccgcgc ccgcccgcca gccggccgac gtcgtcaccg gccagctgct
    28741 ccgcgagtgc ctgcgcgacg acgacgcgga ccggcaggtc gcctggcgcg gactcaagcg
    28801 ctgggcctgg tcttacaccg gcgtcccggt cgaggtcccc gaggagaagc ccgccgtcct
    28861 ccgcgagggc ggcacgtacc tcatcaccgg agggctcggc ggcatcggcc tcaccaccgc
    28921 gcgcgagctg gcccggacgg cgcgggcgaa cctcgtcctg ctcggccgca ccgcgccgcc
    28981 cgaccgcgac gcgtggcccg ccctcctcgc cgacgagggc acggacgagg cgaccaggcg
    29041 gctgctcggc gagctggcgg agatcgagga gctgggcggg accgtcctgg cccgcgcctg
    29101 cgacgtgacc gacgaggacg cgctggcggc ggcggtcgcc gaggccgtcg agcggttcgg
    29161 ccgcgtcgac ggcgtcttcc actcggcggg cgtcgcgggc ggtgggctgc tcgccgtccg
    29221 cgaccgggag gccgcccgcc gcgtcctcgc ccccaaggtc gccgggaccc tcgccctgca
    29281 ccgcgtcctc ggcgacgacg tggacttcgt cgtcctgtac tcctcgatca cctcggtcgt
    29341 gggcgacttc gggcaggtgg actactgcgc cgcgaacaac ttcctcgact cctacgcccg
    29401 ccgccgcgcc gcgtcggggg cgcgcgtcct gtcggtcagc tggggcgcct ggcgcgacgt
    29461 cggcatggcc gtggacgccg cccgcatcac tccgaacgtg ttccgcgaga tgcggggcgg
    29521 caagtggtcc gagcccgccg agcacccgct gctcggacgc cgcctgcacg acctgtcgga
    29581 cgacgtggtg ttctccacgg tgctcggccc cgagtcgcac tggatgctca ccgaccaccg
    29641 ggtcggcgcc atcccgctga tgcccgggtc ggggtgcctg gagatgatcc gggcggcggc
    29701 cgtcacggcc ctcggcgcgg cggcggacga gcacgtcgag atgaccgacg tcgtcttcct
    29761 cggccccatc gaggtccgca ccgaccagga gatgcggatc acgctgcgtc ccgcgcagga
    29821 cggcttccac gacgcctcct tcacggtcgc gcccgccgac accgacgacc ccgccgcctg
    29881 gacggaacgg gtgcgggcga gggtgcggac ggtgcccgcc acgccggcgc ccgtgcacga
    29941 cgtcgaggcg gtccgcgccg agtgcgccga ccaccgcttc gaacccactc cggacttccg
    30001 ctcccggggg atcgtcgact tcgggccgca ctggtacagc gtcgagcggg tcgacatcgg
    30061 cgcgcgccgg cagctcggca ccgtcgcgct gccggaggag ttccgcgccg agtgcggcca
    30121 gtacgtgctg cacccgggcc tgttcgacga cgcggtctcc aacgcccgcg tcatcgaggg
    30181 catccgcaag ggcaacaagt acctgccgct gagctaccgg cgcatcctcg tccgggcgcc
    30241 gctcccgccc cgcttccacg tcgacgtgcg cgagctcgac gacgccgaag gggagatcgt
    30301 cgccgccgac atccgcgtca tggcccccga cggcaccgag ctggcggaga tcgagcagta
    30361 cgcgctgcgg cgggtggacc ccgcggcgtt cgccgagggc gccggcggcg acgagggcgc
    30421 accggcggag ccgggcccgg cgggcgcgcc cgcccccgcg gcggcgccgg accgcgccga
    30481 ctggatgatc acccccgcca ccggcatgga cgcgctgcgg gcgctgctcg gcgcgtgggg
    30541 cgccgcgccg cacctcgtcg tctgcccgga gggactggag gcgaacctgc gccgcgtcga
    30601 gtccctcacc ggcgacgtgc tcgaacgcga gctcggcgac ggcgcggtgg tcgccacgac
    30661 cgccgcccag ggcgagcggc tcctcgacac cccctacgcc gcgcccgaga cgcccctcca
    30721 gcagcggatc gccgccctct ggtcggacgc cttcggcatc cgggagatcg gcctcgacga
    30781 cgacttcgcc gagctcggcg ggaactcgct catggccgtg cagctcgcct ggcgcgtccg
    30841 gcagcacttc gacgtggagg tcacggtggc gcggctgttc cgccgcccca ccgtccgcgc
    30901 cctggccgaa ctggtggaga acgagcaggg cgcgcgctga gcgtccggga aagggagcga
    30961 cgatgacggg atccttcatc gcggcggacg agctgcggac ggcggcgaac ccgctgctgc
    31021 tcggccccgg cgcgcacggg ctgcgcgcca ccgccgaccg cgcgcggatg gccgaggagg
    31081 cgggcgccgg gcagctgtgg ctgagccagg tccccgacga gcacgactcg gcgctcatcg
    31141 ccgcgggctg cgccgccgcg acccgttcga tgcgcgtcgg gaccgcggtc accccggtgg
    31201 cggggcgcca tccggtgctg gccgcgcagg cggcgtccgc gctggccgac ctgtccgggg
    31261 ggcggttcgc gctcgggctc ggcgcgggtc acccgttcat caacgagttc gtgctcggcc
    31321 tcgaccccgt cccgccggtg gcggcgatgc gcgagtacct gacgatcgtc cggaccctgc
    31381 tgcgcgaggg ccgggtcgac ttcgtcggac gccaccacac cgcgcacgcc tccaacgtga
    31441 ccgggcacgg cgccgacgtc ccgatcctgc tcggcggcat gcggccgaag atgatcgagc
    31501 tcgcggcgga gctggccgac gggctgctgc tgtggctcgc cccgctccgc tacgtggagg
    31561 agcacgtcct gcccgccgtc cacgacgcct gcgcccgggt cggccgcgac cccgcgacgc
    31621 tgcccgtcct cgtggaggtc ccggtctacc tggccgacga ccacccgaac ctgtactccc
    31681 acctggaggg cctcatcacc cagtacgcga tgatgccgtc gtaccggcac gtgttcgagg
    31741 cgtccgggtt cggggacagg ctcgcgaccg gcgagatcga ccgcgcgatg accgacgcga
    31801 tcgcgatcgc cggggacgcc gccgagatcg ccgggcggct cgaggagttc cggaccctcg
    31861 gctgcgtgcc ggtccccgcg accgccatcg gcgaccggcc gctggagctg gacacccccg
    31921 acgcgttcgc ccgcttcctc aaggcggtct gcgttgcctg agccggtggc gccgcccggc
    31981 cggtggacgc gtttcgcgct gccggcgagc gcgccgcggg tccggctcat ctgcctgccg
    32041 tgcgccgggg gaggcgcgac ggcctaccgc tcgtgggtgc gggagctcgc cggggcgggc
    32101 gtcgacgtct ggcccgtcca gctgcccggc agggagaacc ggttcgagga ggaccttccc
    32161 ggctccatgg aggacctcgt cgaggagctg ctcgaccagc tcggcccggc gctccgcgcg
    32221 gcgccgtacg ccctgttcgg gcacagcatg ggcgccagca tcgcgctggc gctggccttc
    32281 ggagcacggg cgcgggggct gcccgcgccg gtgcggctgt tcccgtccgc cggccgcccc
    32341 ccgaaccgcc ccgatccgga cccgcccgcc cacagcctgc cgaaggcggc gttcgccgag
    32401 cggctgcgcg cctacgacgc cggctcgttc ctgctccgcg aacccgagct gctggagatg
    32461 ttcctgccca agctgcgcgg cgacttcgcg ctgttcgaga actaccggcc gccggacgag
    32521 gagcctctgg actgcccgtt caccgtcctc ggcgggctcg acgacgcctc cgtgcccgcc
    32581 gccctcctgc ccgcctgggc ggactacacg cggggcgcct tcgaggtcag gctcgtggcg
    32641 ggcggccacc tgttcctgga ctccgcgcgc gacgccgtcg tccggctggt gcgcggccgg
    32701 ctcgtgccgg aggcggcggg atgagcccgg acgggcgcgc actgctggcg gtggcgcgca
    32761 aagaactgcg cgtcctgcgg cggtacccgc tgaccctgct gaacacgatg ctgttcatgc
    32821 ccctgtacca gctcgtcctg cccgtgctgc tcctcggcac cgcgttcctc gtgaaggggc
    32881 ggtccctggg catggacgag ctcaccggca cctccgactt cggcggatgg ctgtccgccg
    32941 gcctcgtggg cgcgaccgtc accggcaccg tcctgtccgg gcccgcccag gccatggcct
    33001 cggagcgggg cctcggaacg ctggagcaga cctgggcgat gccggtgagc cgccgtgccc
    33061 tcgtcctcgg cctgatgacc tgcatgaccg ggctgagcct gctggccggc gtgacgatgg
    33121 cggtcctggt gagcctcctg gcgggcgccc actacgggcc cgggaccgtg ctggtcctgc
    33181 cggtgttcgc cgcgctggtg ccgggcctgg ccgggatggg gctcctcagc gcgtcgctgt
    33241 cgctgctctg gcggcaggcc gtggggctca ccgacaacct cggctacgtc gtgaccgtcc
    33301 tcgccggcgt cacgttcccg gtggcggtgc tctgggacgc gctgcgcccc gtctcctacc
    33361 tcatccccac cacgtgggcg atcgatctga gccgccgcgc cgcgctcggc gcggactccc
    33421 tctacccgcc cgccgtggag gcgtgcgccc tgctggccac ctcgggcctg ttcctcgccg
    33481 gcggcagcgc gctcttcggc cggatggagc gccggatgcg cgcggaggga gcgctcggcc
    33541 agcactgacc atgaccgtcc catttatggg acagctctcg gaagtagtgg tttcggggat
    33601 tattgaaatt gcatctcctt tctatcatca agggcatgtc ggtgactcct gaaatcggtt
    33661 cgcaggcgga gcccggagcg gccgggcaca atctgcgcca ggtctttccg gacggcgaga
    33721 tattcgtcgt gtcggacgac gcggaactga accggtacgc ggccgggctg ggcatgcggg
    33781 ccctgccgct cgaggacgcc tccgggctgc ccgacgacgc caacgtcgtc ctgctcctgc
    33841 gcgcgcggct cgtcagccgc gacctgcgca ggctgttccg ccgcatgcgg gtgctgctgg
    33901 tcccgatcgc cagcttcgac ccgtcccttg cggtcgccga gtacaccctc cgcctcgtcc
    33961 gcgccaccga ctacaccgcg gcgtgcgagt ggaaccgcta ctgggcgcgg agcatctccg
    34021 agcagccggg accgctcgtc ttcgagggca acgggaccga cctgacctgc tcgttcgccg
    34081 accggctcag cgccgacgcg tggctcgacc cgcacatcgg ccccggcaag tgggtcagcg
    34141 tggcgagctt ctgcgagttc tccatcaccg ccccgtcctc ctccgactgg cgcggcgcct
    34201 tcgacatcga cggcacggcg gtcgcgtccg ggctgctcgt cgcccgggac gcgcgcgtcc
    34261 ggccggaggg cgacgagcgg atccgccggg ccgcccggct gcgcgaggag atcgtcgcgc
    34321 gggcgccgat cgagctgcgc ctcgccgacg gggtgctggc ctcggtgacg gccggcggcg
    34381 tggactacac cggcgccgtg atcgacgtga ccaaccccgg ctacgccggg cacacgctcg
    34441 aactcggcct cggcaccaac atgaacctcc tcccgctggt ggactgggag ctgaactccc
    34501 agctcaacga gggggccggg acgctgcacc tcggcttcgg cgagggcatg acgggcgcgc
    34561 acatggactt cgtcgtggcc gagtgcgggc accggttcca ggaaggcggc gcgggcgcac
    34621 cgcgctgaac ccccaccact tcgcgagagg aggagagaca tgcgcgagct gacgatcaac
    34681 gaccagtcct ggaacgtcga cgaggacgac accctcgtcg agggcgccga gcggctggag
    34741 tcggccgacc ccgtcgaggc ggcgtcgctc agctacggct acgccaggat ctagccggtc
    34801 cgggcgcggg ggcggcctgc ccgcccccgc gcccggtcgc ccatctcagc agcggaacgg
    34861 agcggggagc gcgatggccg agcggacgcg ctacacggtg atctcggcgg actgccacgg
    34921 cggcgcggac ctcctggagt accgcgagca cctcgacccg gcgtaccagg aggagttcga
    34981 cgcctgggcg gcctcctacg aggtgcccta tgaggatctc aaaggcgagg acgggacccg
    35041 caactgggac tccgaccggc gcctgcgcga gctggagcgg gacgggaccg tcgccgaggt
    35101 cctgttcccc aacacgatcc cgccgttctt ctccgcgtcc tcgctcggca gccagcgggc
    35161 cgccgagagc gccgcggacc tgcgccgccg ctgggcgggc ctgcgcgccc acaaccgctg
    35221 gctggccggc ttctgcgccg cggcgccggg ccgccgcgcc ggggtcttcc aggtgatgct
    35281 ccacgacgtc ggcgaggccg tcgccgagat cgagcgcgcc gccgcggccg gcctgcgcgg
    35341 cgggctgctg ctgcccggca ccccgcccgg ctccggcctg ccgccgctgt actaccacga
    35401 gtactacgac ccgatctggc gcgcgtgcgt cgaggccggg ctgccggtca acgtgcacag
    35461 cggcagtgcc gcgccccgcg cgggcgaccg tcccgaggac cacgtgctgt tcatgctgga
    35521 gctgcgctgg tgggaccagc ggaccctgcg gcacctcatc ctcggcggcg tgctggagcg
    35581 ccaccccggc ctgaccgtcg tcttcaccga ggaggggctc ggctggatcc cgaacgcgct
    35641 ccgcgcgatg gacggcttcg tcgactccat gcgcaccgcg tccggccgcg gagacctcag
    35701 ccacggcgcg accgtggcac ggaacctgtc gctgcggccc agcgagtact ggcggcgcca
    35761 gtgctacgcc ggggccagct tcatgcaccc gtccgagacc gcgatccgga cctcgatcgg
    35821 cgtgtcccgg atcatgtggg ggagcgacta cccgcacacc gaggcgacct acccctacag
    35881 cgagtccgcc atccggctgg cctacgccgg ggtgcccgag gacgaggtcg agctgatgct
    35941 ggccggcaac gccgcccgcg tcttcgggtt cgacctggag gcgctcgccc ggcacgccga
    36001 acgggtcggc cccgagcggg acgccgtcag cgcgggcgtg gaccccgcgt ccctgcccgc
    36061 cggcgtggcg aagagccccg cgttcgccgg gatcaccccc ggctccagca ggacgcggtg
    36121 ggtcgacaac cgcaaggcgt agccggcggc cggacggcgt ggtggccgcg gtcagccgcc
    36181 ggtgacggcg ggcgcgacct ccttcatgaa gcggcgcagg tcccggacgc ctcccgccgg
    36241 atcgaccatc tggacgacga agtgccgcac gccgaggtcg cggtcggcgc acagccgccg
    36301 cgccagctcc cgcggcggcc ccgtcagcac gaagtccggg acgtcggcgc ggtgcgagaa
    36361 ggcgatctcg tagttcgccg acacccgcgc cgtgcccgtc cgggggatca gctcgcccag
    36421 ccgcgcggtg tcgggcgccc agcagttcca ccagtccgcc cgctcgcgcg ccagcgccat
    36481 cgtcccctcg ccgacgccgc cgatggtcag cggaatcctg gactggacgg ccgccgggcc
    36541 gccctgcggg tcccgcacgg tgaagaactc gccggcgtgg tcgacgggcc gcccgccgac
    36601 gacgaggccg aggacgtcca gcagctcggc cagccgggcc cgccgcacgc ggggcgggtc
    36661 cgcggtgaag cccaggccgg tcagctcgga cggcgaggag ccccagccga gcccgaggtt
    36721 gagccgcccg ccgctgatct ggtcgagcgt caccgccatg cggccgagca gcaccgggtt
    36781 ccggaacgac tcgcacagca ccaggtgccc cacgcggacg gcgctggtcc gggccgcgat
    36841 cgccgtcgcg accgtccagc cctccagcgc cccgccgggc acgcccggca gcgccaggtg
    36901 gtccatgaac cacacggcct cgaagccgag gtcctccgcg gcctccgcca gcgtcgccag
    36961 ctgcgcgaag ctccgccgga cctgcggcag gtacagcccg aacgtcggcg tcacgcgccg
    37021 gtctccacat gcaggaggcg ctccgcctcg tccaggaccc gcccgcactc gtcgatcgat
    37081 ccggacacgg cgacggcgta ggcgatccgc ccgtaccgga tgtcgcggga cggcggggac
    37141 accgtctcgc ccggctcggc gagcgtcacg gcgcgcacca cctcgggcgg cagcccgtcc
    37201 tcgtcgaacc ggatcgcccg gatcgtcgtg tcgtcgcgct cggggtggaa gaaccggatc
    37261 ccggcggtga gcttcctgtc cggggcgagg acgggcggct gcccgcacgc cgcggccgcc
    37321 gacaccagcc ccgggtcgat cccggtggcg taccggccga ggagcgacag cagatcgccg
    37381 cccagccgcc cgttcagctc gatgaccttg gggccgcgcc gcgtcagccg catctcggtg
    37441 aacgtgacgc cctcggtgaa gccgagcgcc gaatgcgccg cctgcaggac ctgcatgacg
    37501 cgcagatcgg cgagcagcgg gtcggcgccg tccacgaagt gcccgagctc ggcgaagaac
    37561 ggcgcgtagc cgacgacctt gcgggccagg tagatcggct gcacccggcc ccggtgcacc
    37621 accgagtcga tgctgatctc cggcccgtcc agatactcct cgaccagcac cggcgtctcg
    37681 tagcgcggcg ccccggccgc atgcgcgccg gccgaccagg ggaaccacga ttcgagctcc
    37741 tcggggccgt ccacccggac gatcccgatg ctgccggcga gcccgcgcgg cttcagcacg
    37801 gccgggtacc cggtccgctc ggcggcgcgc agcgcctcgt cggtccgcga caccgcgatc
    37861 gagagcggct gcggaacgtt cgccccggcc agcgcggccc gcgtgaggtg cttgtcgctg
    37921 caggcgacga ccatctccgg cttcccgccc ggcaggtcca ggctctcggc gacgtacgcg
    37981 gccggcaccg ccaggtcgtc ggaccagctg accacgccgc gcacctcgcc ggcggccgcg
    38041 atccggacgg cctcccggat gagcgcgggc acgtcgaaga cgtcgtcgaa gaccgtgctg
    38101 ccgcagatgt ggggccgttc ccaggtcggt tcggcgcggc agaacaaatg gacccggtaa
    38161 tcggctccga cggactccag aagatggccg cggaaaagct cggacccgtg tccgatgacg
    38221 aggatgagcg gtcgagtgtc gggcatgctg atcccttctc ccgcacggcg gccgatagcc
    38281 gcttccgcat gatcgaatct acagcgcata aagtgaaaat aaaaggacgg gtccgcccgg
    38341 cggcacagcg gagaggacgg ccatgagcca tgacttcctg gacctcgacg gagtcgcgca
    38401 ggccgggctc ctgcggaccg ggcggctgag cccggccgaa ctcgtggacg ccgccatcga
    38461 ccggatcgag cgcctcgacc cggtgctcgg cgcgctcgcc gcggaacgct tcgaacgcgc
    38521 gcgcgacgag gccgcccggc ccgcccgcgg cgccttcgcc ggcgtcccgt tcctgctcaa
    38581 ggacgccgtg cagcactccg ccggcgaccg ctaccagcac ggcatgacct acctgcgcga
    38641 gcatccgtgg gtctcgcccg ccgacaccgc gctcaccggc cgctaccgcg cggccgggct
    38701 cgtcctcctc ggccggacga aggttcccga gctcaccatg tcgcccacca ccgaaccgct
    38761 cgcccacggc ccgtcccgca acccgtggga ccccacgcgc tcgtccggcg gctccagcgg
    38821 cggctccgcg gtggccgtcg cctccggcat ggtcgcgttc gcgcacggga acgacatggg
    38881 cggctccatc aggatcccgg cgtcgtgctg cggcctggtc ggcctcaaac cctcccgtgc
    38941 ccgcatgacc ctcgccccct acgcgtcgta ctgggggccg ctcactcacg agcacgtgct
    39001 gacccgcacc gtgcgtgaca gcgccgccgt cctggacgcc accgccggcc ccgcccccgg
    39061 cgacctcacc gcggccccgc ccccgtcccg tccctggacg gcggaactcg gcgccgaccc
    39121 cgggcgcctg cgcatcggcc ttctccagga gcggccgtcc ggcgggccga tcgcccccga
    39181 gtgcgccacc gcggtgaacg ccacggcccg gatgctggag tcgctcggcc accacgtccg
    39241 gatactcgcc cccggcgcct tcgccgacgc cgacggcgtc tcggccatgg gactcgtgat
    39301 cgccacctcc gtcgcccgcg acgtgaccgc ctgggaacgg cgcatcggcg tccccatgca
    39361 cgacctcgaa ccgggaaccg ccgcggccgt cgcccgaggc tccgcgacca ccaccgccca
    39421 gctcctggac gccctggacg tcctggcccg gtggagccgc cgcatcgtgc gggcctccag
    39481 cgcggtcgac gtcgtcctga gcccgaccct gcccggactc ccgccgcccc tgggcatgct
    39541 gagcggcgac cgcccgctca gcgaaacggc accggcctgg accgccatgg cggaactggc
    39601 cgtcctcagc aacatctccg gccagcccgc gatctccctg ccgctgcacc ggaccgagac
    39661 cggtctgccg atcgggattc agctgaccgc cccgtacgca cgggaggacc ttctcttccg
    39721 gttgtcctcc caactcgaac gaaccgcacc gtggccccag actccgtccc acctcacccg
    39781 gtcctgaccg ccctgctcac ctgccagacg gacctcgcga catgagagcc cgtgatcggg
    39841 gcgcggcatc ggcgatccgt gtgaagcggg acgcgtgcgg gcaaggtgcc cgaatgcgcg
    39901 caccgcggat cggcctgctc tacccgacac cggacaccgg cgaggacgac ttcgcggcac
    39961 tggccgcccg tgtcactcct cgcatcgacc tcgacgtcat ctacatgccg tggccggacg
    40021 gcgtcgacga tctgcgcgaa ctcgacaccg aggcgaccta cgacgcggtc cgccggctgg
    40081 gcggcgaggc gcacttgcgt gccgtcgtcc cgaaggctct ggcagcacac gaccccatcg
    40141 acgcggtcgc gttcggggtg tcctccgcga gcttcctgca cggccccgac ggcgtcacag
    40201 cacaggtgca gaccctgtcg gaagtgacag gagtaccggc gaccagcaca acggcagcct
    40261 tcctggaggc cctgcggcat ctgcggttgc gtcgggtcgc gctggcatcc gtctaccatc
    40321 cgagcggtac cgagcacttc atcgaccgcg tccgcgaggc cggcacccag gtcgtccacc
    40381 gagtggacgc cgacgctcca tccgaccgcg acctggcggc ctggacaccc gatcggatca
    40441 ccggtctggt gcgcgccgcc gctcaccccg acgcccaggc catcctgctc cccgagacgg
    40501 cgctgcacac cagtccgctc gcctcgcgcc tggactcggc cgccggagtc cccgtcctga
    40561 ccgcgaccgg cgtcacgatc tgggccgcct gccggctcct cgggctcgtc ccatcggccg
    40621 acgacgccgg ccccctgttc gcctgacatc gagcccgcac gatccgatgg cttggatggc
    40681 cgcgtggcga gatcgtcctt acggttgccg gatggcggta cggggaaggt ggccggacga
    40741 ccggcggata cggatcgctg ttcagcgggt gcggctcgac ggcggtgagc accgcgtcct
    40801 caggcctgcc cgccccttga agaacgcgtc aatgcgccag gttctggtcc ggttccgggg
    40861 gagcccttcg ggaggggcgg ctgcggacgc gccgtcaccg gtcggcgaag aggcggaggc
    40921 ggtgggcggt cgcggcggcc tccccccggg tggccgcgcc gagcttggcc aggatgcggg
    40981 acacgtggac gctggcggtc ttcgggctga tgaacagggt ctcggcgatc tgccggttcg
    41041 agtgaccctc ggcgatcagg cggagcacct cccgttcgcg gccggtgaga ccgagccgtt
    41101 cggcaggtga ggcgtccgac gcgggaccgg tggccaggtc gatgtgcgcg gctcgggcga
    41161 gcagggcgat ctcctcggcg agggggcgcg cgccgagcgc ggacgcctga gcggcggcgg
    41221 tgcgcagcag gtcgcgggcc ccgtcgcggt cgccggacgc ggcggcggcc tcagccgcgc
    41281 gcagccgggc gccggacgcg gcgaacgggt cgccggccgt gtcccaggcg gcgacggcgg
    41341 ccgtccacga cccgcccgat accgccgcgt attcggcggc gtaggcggtg cagagggcgc
    41401 cgttggcggg tagttgcccg gcccgctccg ccagcggcag cggcacgccc tcgttcggag
    41461 gcaggtgggt ggcgccgcgg gatccggccc gagcttcgat ccgggcgccg tccaccagca
    41521 gcgcccacga ctgcgccgga gtgaggacgg gcgcggccag tgcgcgggcc agtgcggcgc
    41581 gcgcgtcggt gacacggcca tcgcacaggg cgacccgggc ttccaggcgg tcggcgggaa
    41641 ccgcctcgaa gccagacgcc gggccggtca gcgactgggc gagcgtgagc cgctcccggg
    41701 cgaggtccag gtcaccgcgg gcgagagcga tctcgccgtg gagcgcgtgc aacatgccgc
    41761 cggcgccgcc cggcgggtcc tgctccagcg cggccgcgat ctcggccgtg gcgtcgtccc
    41821 agcggccggt cacggtgagg accgcggcga tccggaacgc caggagggcg ccgagagtgc
    41881 gagtgagccc ggccgtccga cagacgtgca taccgcggcg ggccgcggcg atggcgtcgt
    41941 cgtgccgtcc gagcgcggcg agcgcctcgg agcggttgag gtcgatgcgc acttgctggg
    42001 gcgcactgcc tgggcgaccg gtcgcctcca gcgccgccag ggcctcttcg tagcggccga
    42061 gctgcgaaag gacggtcccc gccgtggcgg aggcgttggc gagcaggtcc cggtcgccga
    42121 ggccggacgc gatgtgcatc gcctcggtcg cggcggcatg cgcccggtcc ggcaggccgc
    42181 ggagcatgag cccggcggcg gccaggtcca ggaccttcgc gcgggccgcc ggggcgacct
    42241 catcgccggc gatcgtctgc agcgcctcgt cgaacgcggt gaccgagccg tccctgccga
    42301 ggctgtacag cgagagtccg cggtgtgcgt gcagcagcgc ggcccggccc gggtcggttt
    42361 cctccacgag ttcccgatcg gcgaggccga gagcccgcag tggctcgccg gaccagccgg
    42421 ctgcggcaag cgcgttctcc acgaccgcga accggtccgg ggcgccggtg cggggccaca
    42481 ggccgagcgc ccgtatcagc gtctgggcct gctcggcccg agcgtccatc gcctcggcgg
    42541 cgtcggcggc gcgcagcaac gcgggcagcg ctcgcccggc gtcgcccgcc tcggaccagt
    42601 ggtacgcggt ctcggcggcg gcccggcccg gtgaggtgag cccggggtcg cgttcgaggg
    42661 cggcggcgta ggcacggtgc aacgccaccc gctcggccgg gagcaggtcc gcggcgaccg
    42721 cctcgtacag cagggagtgc cggaagacgt acccgtcgcc gtcggccacg aggatctgcg
    42781 cgtcggccgc gacgcgcagc gccgccagca ggtcgggcgc ggcgacgccg gcgacctcgg
    42841 cgagcaggtc gtgcgccacc cgcggcccgc cggccgccgc gacccgcacc acctcccggg
    42901 cgccgtccgc aagctcggag aaccgctcca gcagcaggtc gcggagggtc gtcggcagcc
    42961 gcgtcccgct cgtgcgggcg agctcggcgg cgaacagcgc attgccgccg gatgcctggt
    43021 agacgcggtc caccagggcc tccggcggcc gtttcccggt cagcgcggcg agcaacccgg
    43081 ctgtctcggc ccggttgaac ggagcgacgt cgacccgccg gaccgaaggg aggcgttcca
    43141 gctcggcggt gaaggcgcgc agcggatggc gggcgccgag cgtgtcggtg cggaaggcga
    43201 gcaggaccag aacgcgggtg ccgcgcaggc tccgggcgag aaggcccagc aggtcgcggg
    43261 aggaccggtc cgcccagtgc aggtcgtcga tcacaagaag aagcggacga tcggcgccga
    43321 ttcgttcgag cagcgtggtg aacgactcga acatgcgggc ctggccggac ggttccgcgg
    43381 cggtgccgga atccggcagc agccggtgca gcagcgacgc tccgggcacg atggcgtcca
    43441 gggcgtccgt cccgaggtcg cggacgagtg agcggagtat cgcggtcacc ggagccagcg
    43501 gaagcccttc ggcgcccagc gcgacacaac tgccgcgcag cacccggacc ccggagtcgg
    43561 ccagccgctg tgcgacatgg tccatgatcc gggttttgcc gaccccggcg tccccgccga
    43621 gcagaacgaa ccttgcttcc cccgcctcgg agtcccggaa cgccgcgtcg atcagcgcga
    43681 gctcttcccg ccgcgccacc agccgcgcag ccgaagtgat cacaacatgg acggtaccgg
    43741 gaatgccccg ggcgtcatct tgaggagtcg gatagggcat ttgccggacg ctcgggaacc
    43801 tcctcagggc acaggctcgg ggcatccgat cccgaggaga cgcgatgccc ggcaaccgcg
    43861 tgaccgtcct gctcgcgggc gccggagcga ccggcctgac ctgcgcggcg tttctcgccg
    43921 accagaaggt cacctgcctg ctcgtcgagc ggcatcccga ccagctcacc ggccgcgcgg
    43981 gcaccgcgtg gactcaggcc gcgcagacgc tggacgtcac cacgcaccac ctcggcatcg
    44041 agagcctggc tgcacacggg atcggcgccg acggcgggct gctcgtccgg cccgacgggg
    44101 tcgtcgcccg gcgaagcacc ggcaaggcac cagcggatct gtcgaagcag gcccccgacc
    44161 cggccaggag cctggcatga gcccgaccga gatcacggcg gaaggcgcac gggccgaaca
    44221 cgtcgtcgtg gccatggcgc agcaacacga cgtcgccgga ctcagcttcg acaacggcgc
    44281 gagcctgctg aacgtacgga ccatggacgg cgccgggcct ctgctgcgcg gtcgattcac
    44341 cgatccgctc ccactggtct gggccgcgga cgccaacgtc cacatcgagt accccctcgg
    44401 ggcgcggctg gcgcacacct cgcgcccggg agaactgcac ttgtccgccc ggaggccgtg
    44461 gtcggtggac gtgcacggcg gcaccgatcg gttcgacgcc gacctctccg gtctgcgcct
    44521 gagctcgctg acgtttcaca gcggcctggc acacgcccat ctccgcctgg gcggtccacg
    44581 gggccgccgc atgatccggt tctcgtcggt gacggacctg gtgctcaccc ggcccgtgaa
    44641 cgtcccggtc cgtgtggagg cgaccaaggg cgtcagccgg ctcggcctgg acgaccgcag
    44701 cgtcgacgcg gccaacgggt tcgaaggcca gacccatgac tacaacgacg ccgacgaccg
    44761 ctacctgatc ctcctgaccg gcgacgtggc ctcgttgacg atcacaaccg ccccggagct
    44821 cggttgagaa gagcactcgg ctctccgcgc gaccgccgcg cgacttccac acgcgacctg
    44881 tacggaagga actctgtgct gaacagcgga atcggggggc gtcgctggac gcccgaagcc
    44941 gcggcagaac tcacgccgat gtcggacgcc gtcctgtgcc gcgctgggca gggcgcggca
    45001 tgacgcgcga tccgtcgatc acccggcgcc ggttgctgcg cgccaccgca gtgggggtgc
    45061 ccgcgctggc cgccggctcg gcgggcgtgc ccgcgtggct gtgggcctcc gccgacgtct
    45121 ccaccgtcgg gcgaaccagg ttcgtcaacc gcctcgccat cccgccgctg gccaccgggc
    45181 gccgcgacac cgacggcgcc cgcgtgtact cactgcgggc cgccgcgggc acgcgcaggt
    45241 tcaagcccgg ccggccgacc aggacctggg ggttcgacaa cggccacctg ggcccgacgc
    45301 tccgggcgat gcggggcgag accgtacgaa tcgacgtacg caacaccctg cgggagacaa
    45361 cgaccgtcca ctggcacggc atgcaccttc cagcgcgcat ggacggcgga ccgcaccagc
    45421 cgatcccgcc cggcggcgca tggtcgccga cctggcgcat cgaccagccc gcgacgaccc
    45481 tgtggtacca cccccacccg cacggcgcga ccgcgcgcca cgtctaccgg ggcatggccg
    45541 gcctgttcat catcgacgac ccggcggacc ggcggctggg cctgcccgcc aggtacggcg
    45601 tggacgacat cccggtgatc gtgcaggacc ggaagttcga cggcgacaac cagttcgacg
    45661 agtcccggcc gctgatcggc ggcgtcgggc tcatcggcga cacgctgctg gtcaacggca
    45721 cgatcgggcc gtatcacgac gtcacgaccg agcgcgtgcg gctgcgcctg ctcaacgcct
    45781 ccaacgcgcg gacgcaccgg ttcgcgctct cggccgggcg gacgttcacg ctgatcggca
    45841 cggacggcgg gctgctgccc gagccgtacg agacgcacac ggtgcaactc accccggggg
    45901 agcgggccga ggtcgtcgta cggctccgcc ccggggaacg gatcgtcctg cgcagcatgc
    45961 cgcccgacct caacgtgaat ttctggaact cccgcttcga aggcggcgac gacgccttcg
    46021 acgtcctcga gctgcgcgcc gcgccccggc tcgccccgtc cgcggccccg cccgcggccc
    46081 tcgccccgcc accccggctc gctccgttcg gccccggccg ggtggaccgc cggttcaaac
    46141 tgtccggcca caagatcaac gagcgcagga tgggcatgga ccggatcgat ttccgtatcg
    46201 accgggaccg caccgagatc tgggagctgc gcaacaccaa cggtaccccg cacaccttcc
    46261 acgtccacga cacgcagttc caggtgctct cggtgaacgg cgccgccccg cccccggaac
    46321 tgcgcggctg gaaggacacc gtgtacgccc ggcccggcgc ccccatcagg atcgccgtcc
    46381 gcttccgcgg ctacgccgac ccgaaccacc cgtacatgta ccactgccac ctgctctacc
    46441 acgaggacca gggaatgatg ggccagtttc tggtcaccga acccggccga tccccgggcc
    46501 cgccacctct cacgcaagac ggccaccacc acatgtgaca cccacctagg agcaccgatg
    46561 agacgaacaa ggatctgggg actcgtcgcg gccgcggtac tgtgcgggtc cgcgacctcg
    46621 accccggcga aggccgatcc gggcagcgca cccgtcatcg acatcacggc cgatgacgac
    46681 ggtttcaccg cgccggcgtc ctacaccagc gggacgacgt cgttccgggt gaacacgagc
    46741 gcgaccggcg accgcggcac catcatcggc ctggcccggc tacggcccgg cgccaccccg
    46801 gccggcttcg ccgaccacct gggcaaggtc ttctccgacg accccaaggt cgccgtcccg
    46861 gcgggccggg cgctgatggc cgaggccgaa ctcctcggcg gagccgagtc ccaggccggg
    46921 cgatcaacga ccttcaccac catggtgcgg cccggcacct actacctgct caactacctc
    46981 gacttcgaga cccggacccc ggcaggccca caggcgctgc acaagctgac catcacccgc
    47041 gagcgacaca ccggatcggc cccgcgcccc ggctcggtcg tcggcatgac cgacacgccg
    47101 tccgggccca gattccacct gcccgaccag atcaaggcgg gcgccccgct gctgctgacc
    47161 aaccatctga agcaggtcaa cgaggccatc ttcataccgg tatcacccga taccagcaga
    47221 gccgagatac agaaattctt cgaaggagtc cagaacggcg aatggggccg gcctccgttc
    47281 accggagcgc cactgggcag cccgccactc tctccgggcc gcactctgac actccaggcc
    47341 ccgctcaagc cgggccggta cgcggtcatc acctgggtac tcgacctgac cgacggcgtc
    47401 cgcctcgccg ccaagggcat gcactccctg atcatcgtga catgacccgc tgacgcccgg
    47461 cagcgtgaca ttaggccacc tgcgcctgcg gcaatggcgt ccgcaggcgc aggtgctttg
    47521 ccgcagagac ctgcgacagg cgtcctggat tgctgcggta aagccaccta acggcggccc
    47581 attcaggcac gggcgtggcg gagccatgaa agtggaagcg gttttgtcag gaggggccgt
    47641 ttcaaggctg ctcgcgccac agtgattcag cccttggagt tcggtgcaga cgacgagagg
    47701 cgagcctata gaagcggaag tattgggatt gctgatagcc tctggctgct ggtccagctg
    47761 gcgccgttcg tcacggggct ggtggcggcg ccgaaggcac ggcacacagt cccggcatcg
    47821 ctaagggggc atctcctgta cgggtcaggt caaacatcgg ccgcaaattg ccgatacgag
    47881 ccgctcgtca cgcaatcact aggcccgtgt catcgtagag gtagaaagcg atttcggtga
    47941 gcattccact gacatccccg tgtggtgact cctaatggct gggcgaccgt ttatttggtt
    48001 tctcgctctg gcgagttggg cggtaacgct ggtcatgatg aaccttgtcg gtgccgggca
    48061 gtcaaagcga attgcttcga ccgacacgtt cggagaccct gtccccgcag gagactcttg
    48121 ggcatggggt gcggcgacgc tcgcgatgac ggccgtcatc gccgccatgc tgctcctggc
    48181 ctcgatcgat gtcgttcgcg tgctgcgcgg ccagggtggt gtggtgtccg taacgagaat
    48241 tcccgctgcg ttgagcgtac tgccgagttt gctcgtgtgg tgtatagggg ggctcgtcgc
    48301 cgcattcgcg tggtacttca tagatgattg cggcaccggt gctgccgccc cgtgtctgga
    48361 ccgtccaggt gccactctct ctgcgctttc cgtgatctgc ctggtcctgc cgaccctgtt
    48421 gctggcattg gtggtgcggc tcggccaacg ctccgcggtc tgcgcgatcc tggctccacc
    48481 atccattgcg agcatatata ttctggcgat tcatctagcg gtaccgcatg cagggtgagg
    48541 tgcagtcgtc ggctgaccag tgagctcttc gatcctgatc acgctgacgc actttgattg
    48601 aggacggagt ccggtcccac ttatggtcga gactgtcctg tcggaatgac aagggcagtt
    48661 caggcgggat tgtaaatggc gagcgtgatc gcggctgcta tagcgagctg cggggccggc
    48721 cgaccatgtc gaacttcgct tcgactccct cggacgcagt accgcacggc ccggccccgt
    48781 cactggaact tgtcgacttc cgcccacgaa cccgccgccg cccgcccgca tcgaaacggt
    48841 catgatcatc gaatccgcgc tctggcccgg cgacccggcc gcctacaacg ccctgatcat
    48901 cgtcatcgtc gcgctgatcg tggcgggtat cgtgtggacc gcgacgtacg atcacgtccg
    48961 gaccaagcgg ctccacgcgc acgcggccgc gttcggctgg tcgccggtcg gcgccgccga
    49021 tccgatgccg ggcccggtgg ccgaagccgt gcggtcccgc cggtccaagc tcgcgttcgc
    49081 gacggagcag ccgtacccga tatggctggt ctggcagcag ccgtccacgg acagcaccgg
    49141 gcaggcgcgg gagctgaccc gctacttcct cctcatcggc tccgagtacc cggacgtgcg
    49201 ggtcgtccgg cgcaccgccc tcggcggcct cttcaagccc gtccgcggcg ccggcaccgg
    49261 cgaccccgcc ttcgacagga agttcctgat ccgcgggccc ggcgggcacc gggcggccga
    49321 cctggtcact ccccaggtcc gcgcggcgat gctggccggc gacgcgcccg cctgggagat
    49381 caccgccggc gtcctggtcg cgtcacaccc cgacgctccg acccggcgca ccctccagcc
    49441 gcgcgccgac gcgctcaccg acctggcgcg catgctgacc gcgcccccgc tccagcggcc
    49501 tgaccggcgg gtgcgtcaca ctcccgggac ccggttcgtc agtgcgatca gcacggacga
    49561 cagcgatcac gcagacggat catgaacgaa cggaaccttc cagccgaacg gttcagggag
    49621 caccgcacgc atctcaagcg gtggcctacc ggatgctcga ctctctgacc gaggccgatg
    49681 acgccgtcca ggagtcctgg ctcggctcgc ccgctccgac gcctacgaga tcggcgacct
    49741 cggcggctgg ctcaccacgg tggtcggctg ggtctgcctg gacatgccgc gctcgtgcac
    49801 gcagcggggc gagaccccgc aggaggcccg gccgccggac cctgtcgtgc gcggcgagtc
    49861 cgccgatcgc gagccggagg cgctgatcgc cggctcggtc gggctggcct gcttgtggcg
    49921 ttcgtcctac aggacatgtt cggcatgccc atcgacgaga tcgccccggt catcgacagc
    49981 acccgggtca cggccggcaa gctccccagc cgcggccggg agaagcacat caactgcaac
    50041 accgacaccg tcccggtgac cgtcagcaag ctgcgctcca atctcggcgc gctgcccctg
    50101 aacgagagct tgtccggcgc cggataccgg ttgcggatat cgccgcgccg gccgatgcga
    50161 tcaccacgtc ggtcgggtcg accgtccagt gagccatacg gcaactcatc aacgggattc
    50221 gcctgcgggt gccaggccgg tgcgctagtg attctcgatc agcaagcgtt ctggtcctgc
    50281 ccaacccggc ggcacgaacg cgctcgcgtc cgcagtgaaa aggcgtccgc cagggcgggc
    50341 gcccacttgc agttcgatca acccggccaa gctgcgaggg cacagcacta ggaggccggg
    50401 gctgtgcggc ggtgcaggtg gagtgtcagg gcaagcaggc cgagcggggt ggccacggcc
    50461 agggcgccga gcgcttggtg ctcccgggcg gcgaccgtcg cggcgcatcc ggacgtgccg
    50521 agttcatcga gtccggcatc ggggccgtac tgccgcttcg tgaacgcctc ccggtcgaac
    50581 aacgcgggaa caccgcacga catcggccgc tggaagcttc cgttgttgtc gaaggacggt
    50641 gggaggaaca tcaggccgag cgccaaaagg aagccgccca ccgccgggac cgcgcagacc
    50701 caagcgcaaa tgagcaggtc tcgattggtc cgggccatgc tggtttcggt cacgccgaaa
    50761 gacgatatcg cggtgtccgc ggggctgctc ggtgaccgcg accgcggaaa cccgccgtgg
    50821 ctggagattc tctggcgcgc gggccaggcg ggcacgcgac atagaccgct gtcgacgtcg
    50881 gcggtgtcgg cctgcccgcc ggcaatagcc atcagcaggg acggcaccgc accacggctg
//
