LOCUS       NZ_CP053892            26917 bp    DNA     circular CON 05-MAY-2024
DEFINITION  Actinomadura verrucosospora strain NRRL:B18236 chromosome.
ACCESSION   NZ_CP053892
VERSION     NZ_CP053892.1
KEYWORDS    RefSeq.
SOURCE      Actinomadura verrucosospora
  ORGANISM  Actinomadura verrucosospora
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 10214634)
  AUTHORS   Samborskyy,M.
  TITLE     Actinomadura verrucosospora NRRL-B18236 (PFL_A860) Genome sequencing
            and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10214634)
  AUTHORS   Samborskyy,M., Dickens,S. and Scott,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAY-2020) Biochemistry, DNA Sequencing Facility,
            University of Cambridge, 80 Tennis Court Road, Cambridge,
            Cambridgeshire CB2 1GA, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-DEC-2016
            Assembly Method                   :: Newbler v. 3.0
            Assembly Name                     :: A860_AS2.mpe1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013211575.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 03:37:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,277
            CDSs (total)                      :: 9,181
            Genes (coding)                    :: 9,110
            CDSs (with protein)               :: 9,110
            Genes (RNA)                       :: 96
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 18 of 71
            Pseudo Genes (incomplete)         :: 57 of 71
            Pseudo Genes (internal stop)      :: 2 of 71
            Pseudo Genes (multiple problems)  :: 6 of 71
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:15:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9439759
            Orig. end                         :: 9466676
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP053892.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Peter Leadlay,
            NRRL-B18236 (patent collection, not in online catalogue).
FEATURES             Location/Qualifiers
     region          1..26917
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="31"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..26917
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26917
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:16917]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16917
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     misc_feature    122..136
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     gene            551..1399
                     /locus_tag="ACTIVE_RS42590"
                     /old_locus_tag="ACTIVE_8535"
     CDS             551..1399
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="ACTIVE_RS42590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8535"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_173100252.1"
                     /transl_table=11
                     /translation="MENAQRPTVRSRKLGQRLRAIREDRGLTLQKAARLLNRTPSSLSK
                     LETGKRGIRRPALENMLDRYGLTDPDERQHLFDLASRATEKGWWRRYEGKLSPSMLDYI
                     ALEADATSIKTFQLHLVPGLLQTPEYARSVVECGFIQGFTPDVDGLVEIRLKRQRIVAA
                     SNSTELWAIISEAALRQQFGGRCVMKAQLKRLIEMSELPHVTVQILPFSVGGHAGLNGS
                     FTTLSTNDLSVVLVENLTTGWYLEGDDDIRQHEVTFEHLKTAALAPSASRSLIQRLLSE
                     L"
     gene            1396..1728
                     /locus_tag="ACTIVE_RS48395"
     CDS             1396..1728
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016070.4"
                     /locus_tag="ACTIVE_RS48395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_173100253.1"
                     /transl_table=11
                     /translation="MTNHGFVFSPWQKSSHSGSVGQECVEVAAVWRKSRHSSGGEGQCV
                     EVAPAWRKSSHSEGGGGQCVEVAQAERRVAVRDSKDPDGAVLAVAPAGWAALLDGVKAG
                     SFDLAR"
     gene            complement(1801..2958)
                     /locus_tag="ACTIVE_RS42600"
                     /old_locus_tag="ACTIVE_8537"
     CDS             complement(1801..2958)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS42600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_8537"
                     /product="hypothetical protein"
                     /protein_id="WP_173100254.1"
                     /transl_table=11
                     /translation="MDDLTLIRRMHSAERPPSPETARAARRRLLAEATGPGARNRRVAP
                     LPRSKRWVTLVAAATACVLAGVSWTAYRWETRPLYHPEPLADQNGPASTFLLAAADAKT
                     QHASDGRFWYVHRVIGETVVASSPLRPGVHYTVQLTKDTYDLGAKTAKEFGTLPHEKKP
                     STGLRWDDLNVHVRPATPADKKAWETDLQPGAQDLHLTGPDEERGPFKQEGAELDFGVE
                     DERRLPANPSKLRAWILNYATKFDHQPLREPDLYLFTAAPILLVDRVVTDRVRIATYRM
                     LAGLRGVKTINGTDAAGHPGKGVAMRQTTADYGTIEWQLLIDPETGRLTASQGIVVKPG
                     RKNSGLAPGTRQYFEIVKTAEWTNAPRDSLLPKDVTDPNWQPPMN"
     gene            complement(2951..3553)
                     /locus_tag="ACTIVE_RS42605"
                     /old_locus_tag="ACTIVE_8538"
     CDS             complement(2951..3553)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012886889.1"
                     /locus_tag="ACTIVE_RS42605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8538"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_173100255.1"
                     /transl_table=11
                     /translation="MTSAPSQTGASAEQEPSDADIVTAALRDPERFADLFDRHYQEIHR
                     YVDRRLGADAADDIAAETFLIAFRRRAVFDTAHASARPWLYGIATRLISRHRRDELRRY
                     KAMARMRTADVVESHESSVTSAVAAASFGLSPALARLRHGDRDVLLLVALAELSYPEVA
                     EALGIAYGTVCSRLSRARKQVRAALRASGHDEEDDHG"
     misc_feature    complement(3963..3975)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.41"
                     /tool="antismash"
     gene            complement(3972..4586)
                     /gene="bluB"
                     /locus_tag="ACTIVE_RS42610"
                     /old_locus_tag="ACTIVE_8539"
     CDS             complement(3972..4586)
                     /EC_number="1.13.11.79"
                     /GO_function="GO:0016722 - oxidoreductase activity, acting
                     on metal ions [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032363 - FMN catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="bluB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009081635.1"
                     /locus_tag="ACTIVE_RS42610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8539"
                     /product="5,6-dimethylbenzimidazole synthase"
                     /protein_id="WP_173100256.1"
                     /sec_met_domain="PF00881 (E-value: 7.3e-27, bitscore: 93.5,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLYDVIHRRRDVRAEFTGAPIPDGVLDRVLTAAHAAPSVGLSQP
                     WDFVLVRDPDVRRAFHDHVRSERDAFAATLTGDAAARFARIKIDGVLESTVSVVVTYDA
                     ERGGPAVLGRHAIADAGLYSVCLAIQNLWLAATAEGLGVGWVSFYREPHLRDLLGIPAG
                     VRPVAWLCLGPVTHLETVPDLERHGWRHRRPLEAAVHHDRW"
     regulatory      complement(4621..4813)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            complement(4857..5294)
                     /locus_tag="ACTIVE_RS42615"
                     /old_locus_tag="ACTIVE_8540"
     CDS             complement(4857..5294)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025445.4"
                     /locus_tag="ACTIVE_RS42615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8540"
                     /product="DUF4260 family protein"
                     /protein_id="WP_173100257.1"
                     /transl_table=11
                     /translation="MSTVTAPAARENDARKQLVPTAVRRGAWAANGLFWSAFAVLEAVN
                     HGWVAGGVAAAFFIAPDLTFLAGVRDAQTVQPGQLPARAVPYYNAAHRALVPLAFMVLY
                     TVTPPMQWAPLFAGLCGWMAHISIDRAVGYGLRTKDGFQRR"
     gene            5459..6898
                     /locus_tag="ACTIVE_RS42620"
                     /old_locus_tag="ACTIVE_8541"
     CDS             5459..6898
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS42620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_8541"
                     /product="hypothetical protein"
                     /protein_id="WP_173100258.1"
                     /transl_table=11
                     /translation="MSQWSQRAQLRLWIAAVAITAEPVLEKAATSLFGPTTSRLSFGVG
                     ITSIDACQGWRHQIELWSVPGYRLLHTWPILVVLPAFLLWLLLRHRAVGWAAALLLGAV
                     TLPEPVLYGYDVARWGTQCTRMWLPFGSWEVARWVLTAVPVLLILASTCRPGRRTVRLV
                     GGTVAAGLLLSVAADREVPHRYGASEDECRHVNYAAAPERTSYTAAMAGLSQRERQIAF
                     LCSRRGFLMGYSGGPMRHDSLSDAEQIEMGRRACRGERPMTNGVRLGIAPVSLQDMAYL
                     CPGKADERQAVQRRSLAALHAKYQRERAKAEASCRRGVPEGFGPVRQATHVIDGDESGS
                     YTVEDEDDGLGASFDPALKEGLIASAGHGATVIAGTEGPLCLTVRVYRKAPPVEPRGWD
                     RVEEVGVDNPHGRARLMSMDGLLPFPVVNAAGPGRYRIRIYVRGRTEPEALMDEPPKEH
                     HLLVVFPGKSEKRKVYKNTEH"
     misc_feature    5492..5494
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6934..7503)
                     /locus_tag="ACTIVE_RS42625"
                     /old_locus_tag="ACTIVE_8542"
     CDS             complement(6934..7503)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025390.4"
                     /locus_tag="ACTIVE_RS42625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8542"
                     /product="DUF4240 domain-containing protein"
                     /protein_id="WP_173100259.1"
                     /transl_table=11
                     /translation="MDERAWWDLIEDARAEAGEHADDRDSPDDPLIGLVTDRLLALDGP
                     GIVAFDATLTRILDTAYRRPLWNAAYLIEGGCGDDGFMDFRAGLALLGRDVFTRAVDDP
                     DSLADVPTVVRMAKEDKGWIGAEGLLYAAVKAYERVIGEREAFDTAVEAALASMQGLEQ
                     PLGETWDVDDDAENRRHLPRLAALFL"
     gene            complement(7580..8260)
                     /locus_tag="ACTIVE_RS42630"
                     /old_locus_tag="ACTIVE_8543"
     CDS             complement(7580..8260)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020380060.1"
                     /locus_tag="ACTIVE_RS42630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8543"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_216858145.1"
                     /transl_table=11
                     /translation="MTTEDGRRAGTGPGEIADDGSAVEFYAALPPDVPSAALVHTAIPA
                     GTTVLELGAGTGRVTRPLLDFGHPVTAVDGSAAMLARIEGARTVCSPIQELDLPDRFGC
                     VLLMSFLVNYGDRDALLATCRRHVRPDGVVIVQRDTDGRWLDGAPREWERDGVRYRKAH
                     VERPEPGIVVATMEYRIGERRWTHTFTTRRLGDEDLPAVLEAAGLRLDGFLDDDGAWFT
                     ARPL"
     misc_feature    complement(8320..8333)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            8370..8816
                     /locus_tag="ACTIVE_RS42635"
                     /old_locus_tag="ACTIVE_8544"
     CDS             8370..8816
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024854.4"
                     /locus_tag="ACTIVE_RS42635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8544"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_173100260.1"
                     /transl_table=11
                     /translation="MSDSVEPISPSAARAAQEVRVVFSRLRRRLREIGGAHDLTPSQAA
                     VLSRLLKDGATTASALAAAERVRPQSMAATLGALEERGLIRRDPDPQDGRRQLVTPSDA
                     GREWVEGSRQARDEWLSRALQDHCTEEERETVLRAFTVLDRLVQ"
     gene            complement(8853..10001)
                     /locus_tag="ACTIVE_RS42640"
                     /old_locus_tag="ACTIVE_8545"
     CDS             complement(8853..10001)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634236.1"
                     /locus_tag="ACTIVE_RS42640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8545"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_173100261.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.3e-36, bitscore:
                     123.9, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.9e-20, bitscore:
                     71.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.1e-47, bitscore:
                     160.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDFKLSDEQEELRRTVERFARETVAPVIGDLYERGEFPYDIVAA
                     MGKMGLFGLPFPEEHGGMGGDYFALCLALEELARVDSSVAITLEAGVSLGAMPIYRFGS
                     DEQKARWLPMLTSGEKLAGFGLTEPGGGSDVPGGMRTTARLDGDSWVINGSKAFITNSG
                     TDITAFVTVTAFTGDGEISTIIVPSGTPGFTVGRKYSKVGWSSSDTRELAFDDVRVPAE
                     NLVGERGRGYAQFLRILDEGRIAIAALSVGLAQGCVDECLRYAGERQAFGKEIGRYQAM
                     QFKIADMEVRAHTARLAYYAAAAKMLAGEPFKKEAAIAKLVASNAAMDNARDATQVFGG
                     YGFMNEYAVGRFYRDAKILEVGEGTSEVQRMLIARALGLPAS"
     gene            complement(10001..10930)
                     /locus_tag="ACTIVE_RS42645"
                     /old_locus_tag="ACTIVE_8546"
     CDS             complement(10001..10930)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892860.1"
                     /locus_tag="ACTIVE_RS42645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8546"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_173100262.1"
                     /sec_met_domain="HMGL-like (E-value: 4.4e-46, bitscore:
                     156.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMATPLPGLPDRVTIYEVGPRDGLQNEKAIVPVEVKSEFVTRLAG
                     AGLTTIETTSFVHPKWVPQLADAEELLGVLPRSGNLRYPVLVPNERGLDRALANGITEI
                     AIFGSATETFARRNLNRTVDESLAMFAPVVERARAEGLWVRAYVSMVCGDPWEGDVPIE
                     QVVSVATRMMDLGCSQLSLGDTIGVGTPGHVTALIEALVAAGIGTDRLAVHFHDTYGQA
                     LANTLAALRAGVTVVDASAGGLGGCPYAESATGNLPTEDLVWMLDGLGVETGVDLAALA
                     ATSRWMAERLGRPSPSRVVQALSPATEK"
     gene            complement(10927..12864)
                     /locus_tag="ACTIVE_RS42650"
                     /old_locus_tag="ACTIVE_8547"
     CDS             complement(10927..12864)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540603.1"
                     /locus_tag="ACTIVE_RS42650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8547"
                     /product="biotin carboxylase N-terminal domain-containing
                     protein"
                     /protein_id="WP_173100263.1"
                     /sec_met_domain="ATP-grasp (E-value: 1.5e-07, bitscore:
                     30.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.3e-06,
                     bitscore: 27.1, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDSVLVANRGEIAVRVFRTLRRLGIRAVAVHTDADAGARHVREA
                     DEALRIPSYLDVDAVIGAARASGAAAVHPGYGFLAENTAFARACADAGLVFIGPPASAI
                     EAMGDKIRAKRTVAAAGVPVVPGRDEPGLSDAELEAAALEVGLPVLLKPSAGGGGKGMR
                     LVRDAADLPDAIASARREARGSFGDDTLLAERFVENPRHIEIQVFADAHGNAVHLGERE
                     CSLQRRHQKIVEEAPSPLLDEASRARMGAAAVAAAQAVGYVGAGTVEYIVSADRPDEFF
                     FMEMNTRLQVEHPVTELVTGLDLVELQLRVASGEPLPFAQDGVRLDGHAIEARVYAEDP
                     ARGFLPTGGTVLALDEPEGARVDSGLGVGTEVGGSYDPMLAKVIVHGADRTEALHRLDR
                     ALAGYTLLGVPTNVAFLRALLKHPSVASGDLDTGLVERALDELTSDGGVPPEVLAAAAL
                     DRMLALEPADGDPWAIPDGWRPGAHAWTPWIITPSGGEPVEVRVQGRAAAARVAIGDGE
                     PVAASLTGTALTYGGRTVSFTAARDGRTLWLGRGGHVWALAEHVKAEGGAAADASGDGV
                     LRSPMPGTVLAVKVGEGDRVDEGQPLVVVEAMKMEHTVTAPRAGVVAQLPARAGAQVAL
                     DAVLAVIEEA"
     gene            complement(12921..14534)
                     /locus_tag="ACTIVE_RS42655"
                     /old_locus_tag="ACTIVE_8548"
     CDS             complement(12921..14534)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012852328.1"
                     /locus_tag="ACTIVE_RS42655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8548"
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_173100264.1"
                     /transl_table=11
                     /translation="MSGPEIGSLADAAGEAFKASAAHNEALAAELRDRVDRAGRGGPER
                     ARERHVARGKLLPRDRVDTLLDPGSPFLELSPLAANGMYGDEAPGAGIITGVGRVSGRE
                     CVIVANDATVKGGTYYPVTVKKHLRAQEVALHNRLPCLYLVDSGGAFLPRQDEVFPDRE
                     HFGRIFYNQATMSGRGIPQIAAVLGSCTAGGAYVPAMSDEAVIVRGQGTIFLGGPPLVK
                     AATGEIVTAEELGGGELHSRTSGVTDHLAEDDAHALRIVRDIVGTLGPREPRPWDVAAP
                     EEPAVDPSELYGVVPPDPRTPYDVREVIARIVDGSRFQEFKKEYGATLVTGFARIHGHP
                     VGIVANNGILFGESAQKGAHFIELCDRRSVPLVFLQNITGFMVGREYEAGGIAKHGAKM
                     VTAVSCARVPKFTVVIGGSFGAGNYAMCGRAYSPRFLWMWPNARISVMGGEQAASVLAT
                     VRRDQMDARGEDWPAEDEEAFKAPIRDQYEAQGNPYYSTARLWDDGVIDPLDTRRVLGL
                     GLSAAANAPLEPVGYGVFRM"
     misc_feature    complement(14579..14594)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.42"
                     /tool="antismash"
     misc_feature    complement(14584..14597)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 12.94"
                     /tool="antismash"
     gene            14621..15232
                     /locus_tag="ACTIVE_RS42660"
                     /old_locus_tag="ACTIVE_8549"
     CDS             14621..15232
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657842.1"
                     /locus_tag="ACTIVE_RS42660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8549"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_173100265.1"
                     /transl_table=11
                     /translation="MTSYPAAAPGDTGGEPPVAAVNPRRAEILAAAAELFARRGYHGAS
                     IGDVGRAVGLTGPALYRHFSGKEAVLAEMLVDISERLHAEGVRRAADPDPGRALDALLR
                     WHIAFSLDNPALITVHERELDNVPEPQRHEVRRLQRAYVEEWVGVLRRLRPGQPDGRTR
                     AAVHACFGLLNSTPRSAAGLDRDAMDDLLRTMARAALEAA"
     misc_feature    complement(15367..15380)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.81"
                     /tool="antismash"
     gene            15370..16917
                     /locus_tag="ACTIVE_RS42665"
                     /old_locus_tag="ACTIVE_8550"
     CDS             15370..16917
                     /NRPS_PKS="Domain: AMP-binding (9-412). E-value: 3.4e-86.
                     Score: 281.3. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS42665_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541894.1"
                     /locus_tag="ACTIVE_RS42665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8550"
                     /product="AMP-binding protein"
                     /protein_id="WP_173100266.1"
                     /sec_met_domain="AMP-binding (E-value: 2.5e-92, bitscore:
                     308.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVQGVGFYEIASNDPDRPAILAPGVPVSYGELHAEVNRLSNALD
                     GLGLRPGDAVATVLGNRPEFLTVLLAAMQSGLYIVPVSRHLTAPEIGYILADCGAKAVV
                     TESAFAPTVAGAADKAGIAADLRVSVDPADGHRSMAALCASGSAEPPGKRRMGSIMLYT
                     SGTTGRPKGVRRPLLDVPPELLFDIMRRTLATHLGLEPGDEVHLAIGPLYHSAPCVHAM
                     MALNLGHAVVVASRFEPEQTLELIQRHGVTNSFMVPTMFHRMLALPDDVRARYDLSSLR
                     QVYHSAAPIPVETKQRMMDWWGPVLYEYYGSTESGAVVVATPHDWLARPGTVGRAVDGV
                     RIRILDPEGAELPPGETGLIYAAGQPGFEYHGDPDKTASTMRGEFYTPGDLGHLDEDGW
                     LYMSDRRTDLIISGGVNIYPAEIESVLLQHPTVGDVVVIGVPDEDWGQRVVALVEPADG
                     AVAGDDLAADLLAHCEPRLARLKHPRRLEFRASLPRTPSGKLSRSRVRDAYLREQAG"
     aSDomain        15397..16605
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS42665_AMP-binding.1"
                     /evalue="3.40E-86"
                     /label="ACTIVE_RS42665_AMP-binding.1"
                     /locus_tag="ACTIVE_RS42665"
                     /protein_end="412"
                     /protein_start="9"
                     /score="281.3"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="EIASNDPDRPAILAPGVPVSYGELHAEVNRLSNALDGLGLRPGDA
                     VATVLGNRPEFLTVLLAAMQSGLYIVPVSRHLTAPEIGYILADCGAKAVVTESAFAPTV
                     AGAADKAGIAADLRVSVDPADGHRSMAALCASGSAEPPGKRRMGSIMLYTSGTTGRPKG
                     VRRPLLDVPPELLFDIMRRTLATHLGLEPGDEVHLAIGPLYHSAPCVHAMMALNLGHAV
                     VVASRFEPEQTLELIQRHGVTNSFMVPTMFHRMLALPDDVRARYDLSSLRQVYHSAAPI
                     PVETKQRMMDWWGPVLYEYYGSTESGAVVVATPHDWLARPGTVGRAVDGVRIRILDPEG
                     AELPPGETGLIYAAGQPGFEYHGDPDKTASTMRGEFYTPGDLGHLDEDGWLYMSDRRTD
                     LIIS"
     CDS_motif       15847..15888
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS42665_0001"
                     /evalue="4.20E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="ACTIVE_RS42665"
                     /protein_end="173"
                     /protein_start="159"
                     /score="19.4"
                     /tool="antismash"
                     /translation="MLYTSGTTGRPKGV"
     gene            17007..18272
                     /locus_tag="ACTIVE_RS42670"
                     /old_locus_tag="ACTIVE_8551"
     CDS             17007..18272
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853001.1"
                     /locus_tag="ACTIVE_RS42670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8551"
                     /product="chromosome segregation ATPase"
                     /protein_id="WP_173100267.1"
                     /transl_table=11
                     /translation="MEDQKVAPLDNAPTPAAPTLTDLPVITDPGFYTDPAYSAQSVPPE
                     DAAAPGTGLDTVPRAGTARPGGPVAVWPCAGCGRPVPQPVRGARTVRYCQDDGGACERA
                     AHEQRERARETPGLTGQVAWTWEMVERLEAVADRLAGSLVSELGVAGVERRVADARADA
                     AGQIAVAQRERDASQRQAEAAWRETAAARARADAAEGEAAAARAAAEQAAAERDTARRG
                     GQDAKDTADAAVAAQLAAERERDRVASREGELLAALETARTELVGLHGRLSEAETLAEG
                     QRIEAAAARRAADDLRSAVRDAETQRGQAVADRDQIQARARDVDERNRDLSRANEELRA
                     AVQTLTAERDAARAEADRARRRVDALTRPADPRPDGRPAADREPLTGLHPLPPLNGSRP
                     NGSSLDGTDPLAVNEHRLPHAG"
     gene            complement(18384..19094)
                     /locus_tag="ACTIVE_RS42675"
                     /old_locus_tag="ACTIVE_8552"
     CDS             complement(18384..19094)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634229.1"
                     /locus_tag="ACTIVE_RS42675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8552"
                     /product="adenosylcobinamide amidohydrolase"
                     /protein_id="WP_173101813.1"
                     /transl_table=11
                     /translation="METIWRDEDGARLAATVWRAGGGWRAVSSAMLGGGIGPLNWALNA
                     QVRGRYARTDPVVHLAELAASFGLDGPGVGMLTAASVARTMRREDGGVAVSATVGLRVP
                     TWAAAPEGSADPELAPLHMAVPPPAPEPAPEATRRPGTINIVVAVPVALSDAALVNAVV
                     TATEAKTQALLEAGYPCTGTASDAICVAARASGAQEPFAGPRSTWGARIARAVHAAVRA
                     GALDYTEYLRTRPS"
     gene            complement(19097..19867)
                     /locus_tag="ACTIVE_RS42680"
                     /old_locus_tag="ACTIVE_8553"
     CDS             complement(19097..19867)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634228.1"
                     /locus_tag="ACTIVE_RS42680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8553"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_173100268.1"
                     /transl_table=11
                     /translation="MTVSVRGLDVSLGGRPVLKGVSLEVPAGSWTAVIGPNGAGKSTLL
                     RAVLGLLPCAGDIGVAGADLAAMKPRQRARLVAYAPQSPNLPVGMTVFDYTLLGRSPYI
                     PHLGRESARDRAIAGEVLDRLDLTGLADRPLDHLSGGERQRVVLARALAQQTSVLLLDE
                     PTTALDIGHQQQVMELIDQLRLSDGLTVVTTIHDLTLAGQYADDLVLLSGGRVAAAGAP
                     ATVLTRAAIQEHFDARVHVLPGPDGRPLLSLERP"
     gene            complement(19864..20892)
                     /locus_tag="ACTIVE_RS42685"
                     /old_locus_tag="ACTIVE_8554"
     CDS             complement(19864..20892)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546256.1"
                     /locus_tag="ACTIVE_RS42685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8554"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_173101814.1"
                     /transl_table=11
                     /translation="MRGRLRPLPLVVALVLLAATLLAGLVVGAAGLPVGGILAALADKV
                     PFVHVDSGFSVVDENVLFQLRVPRVLMAALVGGMLSMAGAGYQGVFRNPLADPYLLGAA
                     AGAGVGATLVIVVVPGDPGYGVPLAAFAGALLGVAMAYALGSAAGRGNRAATLVLAGVA
                     VSSFLSAVQTFMQQVKAEELQRIYSWILGGVGSADWHQLALVAPYSLVSTVVLLAHGRL
                     LDVLSVGDEEAASLGLSAARVRLTVLVAASLATATAVAVSGLIGFVGIVVPHAVRRLAG
                     GSYRVVLPLSLLGGAAFLELADLVARTVIAPGELPLGVVTAFVGGPFFVAVLRASRRQV
                     ET"
     gene            complement(21305..22222)
                     /locus_tag="ACTIVE_RS42690"
                     /old_locus_tag="ACTIVE_8555"
     CDS             complement(21305..22222)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131483.1"
                     /locus_tag="ACTIVE_RS42690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8555"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_173100269.1"
                     /transl_table=11
                     /translation="MRPVRVLGAAIVTAAVTLAAGCGGDGKTKTADDGAKTVTVQAGNG
                     AVTVPAHPKRIVSLSPTHTETLFAIGAGSQVVAVDGLSDYPSNAPRTQLSGFKPNAEAV
                     IKYRPDLVVLSNDMDGVVKALEKVKIPVLLEPAAEKLDDAYDEITDLGLATGHAAEAKK
                     VTDGMRADIQKTVAASTKGKGLTYYHELDNELHTVTSQTFAGQVYGLFGLRNVADAADK
                     ASGGYPQLSREYLVKKDPDLIFLADTKCCGQNAAALAKRPGFGDLKAVKDGGVVPLDDD
                     LASRWGPRLPQFVKAIGDAVQKTR"
     misc_feature    22335..22348
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     gene            22499..23140
                     /locus_tag="ACTIVE_RS42695"
                     /old_locus_tag="ACTIVE_8556"
     CDS             22499..23140
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020545241.1"
                     /locus_tag="ACTIVE_RS42695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8556"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_246342535.1"
                     /transl_table=11
                     /translation="MESENRRRAPGMSPEQRREMIVRTALPLVAEHGTAVTTGQIARAA
                     GIGEATIFRVFADKDELLDACVMEALRTDHVLAEIQEIPLDQPLPARLAEATAAIEAYL
                     GRMGMILGALHATGRRGRGSHGGGEAADAAIDRASAMARTRGALAELFEPDRDRLRLPA
                     DRLAGMFMGLVFTRSRPPGGPETPAPSLEEYLEVFLYGALTGTTPEGSTE"
     gene            23137..23514
                     /locus_tag="ACTIVE_RS42700"
                     /old_locus_tag="ACTIVE_8557"
     CDS             23137..23514
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892725.1"
                     /locus_tag="ACTIVE_RS42700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8557"
                     /product="VOC family protein"
                     /protein_id="WP_173100270.1"
                     /transl_table=11
                     /translation="MTITLNHTIVTAADNDEAARFFAAVMGLAYTGPHPHARHFVPIKV
                     NEGLTLDFMTVAFPQGHHLAFDVDAATFDAVLDRLDAREIPYGDHPAHPDNGRVDTAHP
                     LGGRGLYFSDSCGNLYELISS"
     gene            complement(23546..24457)
                     /locus_tag="ACTIVE_RS42705"
                     /old_locus_tag="ACTIVE_8558"
     CDS             complement(23546..24457)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012850888.1"
                     /locus_tag="ACTIVE_RS42705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8558"
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_173100271.1"
                     /transl_table=11
                     /translation="MRIGVSLGERGGAGALDKLADDVRRAADDGFASAWMSNIFGVDAL
                     TALAVAGSRVPGIELGTAVVPTYPRHPAALAQQVRTVALALGEGRLTLGIGLSHKVVIE
                     EMYGYDFGRPLRHMDEYLSVLLPLLDHQTASFTGETLRGQIGLTVPNEGRVPVLLAALG
                     PKMLKLAAERADGTVLWMTGPATVRDHIAPTITAAAEAAGRPAPRIVCVLPVCVTGDVE
                     RARERAAKAFEVYGTLPSYRAMMDREGAEGPADLAIIGDEDAVGARIRDLAAAGVTEFV
                     AGEFMPGDDRTRTRAFLRSFAS"
     gene            complement(24507..25154)
                     /locus_tag="ACTIVE_RS42710"
                     /old_locus_tag="ACTIVE_8559"
     CDS             complement(24507..25154)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS42710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_8559"
                     /product="hypothetical protein"
                     /protein_id="WP_173100272.1"
                     /transl_table=11
                     /translation="MTVDPEILRTTRRSLHGAAELLLAGPQYRESGTIRLRVLADGFAT
                     VSAPVLRVAGAELVAGDRTIPLNGATCGELATAADVEAGAPQGLYKDGSGVGADETLDV
                     DAGAAAHLEECFARGNEALVRLAPDVAPVLWPEHFDLAITLDEVNYGISPGDDFLGEPY
                     AYAGPWEPRQGAFWNASVGAARPVRLLPGATALHDFFMEARDRAAHDPARRP"
     gene            complement(25224..25577)
                     /locus_tag="ACTIVE_RS42715"
                     /old_locus_tag="ACTIVE_8560"
     CDS             complement(25224..25577)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS42715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_8560"
                     /product="hypothetical protein"
                     /protein_id="WP_173100273.1"
                     /transl_table=11
                     /translation="MDGEDRALRLTAREKPRDARAAWPRDASDAGQRPAKKAGTRPGRS
                     PRRGAGEYALRSMLSSAWAHDRAADLLEDMAAVHPDEAAAHLETAERHRRWAENDRDLA
                     ERYGPHSGDPDGL"
     gene            25744..26493
                     /locus_tag="ACTIVE_RS42720"
                     /old_locus_tag="ACTIVE_8561"
     CDS             25744..26493
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657837.1"
                     /locus_tag="ACTIVE_RS42720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_8561"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_246342536.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.3e-11, bitscore:
                     44.6, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.8e-06, bitscore: 26.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.1e-06, bitscore:
                     27.3, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLHAADGVRIDAGHLGGDGDLCFVLAHGFTCSWRQPALRRIGAV
                     LHRYGGVVALDLRGHGRSGGHSTVGDREVLDVQAAVAAARSRGYRRVAVAGFSLGGAVA
                     IRHAALHGDVDAVVSVSAPARWYYRDTVPMRRVHWVIEQPLGRLAVRLARGTRIAAKGW
                     DPVPEAPHEVAARIAPAPLLIVHGDADAFFPTEHGWQLYDAARDPKELWIEPGFGHAEV
                     AATPDLIHRIGAWAASAATVMRPDATL"
ORIGIN
        1 ccttgccgcg tagttccgtc ccccagtccc gtgcgatgga cgcgacgatc cgcaggccgc
       61 gaccggtgac gtccagctcg cccgcctcgg cgacgtgcgg ggtcgtcgcc gcccggccgt
      121 catcgatcac ctcgatcctg accgtccgcg ccgagtacgt cacctccacg cggatctgcc
      181 cggcccgccc cgactcggtg tagcgcagcg cattcgttag aagctcgctc atgcacagcg
      241 ccgcgtcgtc caggcacggg tgctcgcggc ccagcacgtc ccgcagccag cgccgcgcat
      301 gccccaccgc ccggtccatc cccggcaaca gaagcgcgtc gaacctcgtg gtcggcgcag
      361 tcatcgctca ctcccttcgc gtcgctgtcg ccgaaaagaa tgagccggac atcgcccgcc
      421 gagcgatgcg ttcccgggcc tcggctccaa gtcctccggc acgcggtccc cggtcacttt
      481 tgactgaggc actgttgccg ccttcgttgg aaaccttcac cgtcacgcaa agtcaaggca
      541 tgattacgcc atggagaacg cgcagcgccc gaccgtgcga agccgcaagc tcggccagcg
      601 ccttcgcgcc atccgcgagg accgcgggct caccctccag aaggccgccc gcctgctgaa
      661 ccgcaccccg tcctcgctca gcaagctcga aaccggcaaa cgcggcatcc gccggcccgc
      721 cctggagaac atgctcgacc gctacggcct caccgacccc gacgaacgtc agcacctgtt
      781 cgacctggcc agtcgcgcca ctgagaaggg ctggtggcgg cgctacgaag ggaagctctc
      841 cccgtcgatg ctggactaca ttgccctcga ggctgacgcc acgtccatca agacttttca
      901 acttcaccta gttccagggt tgctgcagac tccagaatat gctcgctcgg tcgttgagtg
      961 tggttttatt caaggattca cgcccgatgt tgatggcctg gtcgaaatca gactaaaacg
     1021 tcagcggatt gtcgccgcgt ctaattcgac ggagttgtgg gccattatta gcgaggcggc
     1081 tctgcgtcag cagtttgggg ggcgatgtgt gatgaaagcc cagctcaagc gcctgattga
     1141 gatgtcggag ctccctcatg taacggttca gatcctgccc ttctctgtgg ggggtcacgc
     1201 tggtctcaac gggtccttca ctaccttgtc cactaatgat ttgtccgtgg tcttggttga
     1261 aaacttgaca acgggatggt acttggaggg cgatgacgat attcgtcagc acgaagttac
     1321 tttcgagcat ctcaagactg cggctctagc gccgtctgcc tcccgttctc tgatccaacg
     1381 gctactgtca gagctatgac caaccatggg ttcgtcttct cgccttggca gaagagcagc
     1441 catagcggaa gcgtggggca ggagtgcgtt gaggtcgcgg ccgtgtggcg caagagccgt
     1501 cacagcagcg gtggggaagg gcagtgcgtc gaggtcgcac ctgcgtggcg gaagagcagc
     1561 cacagcgagg gtggcggcgg gcagtgtgtt gaggtggcgc aggctgagcg gcgggtggcg
     1621 gtgcgggact ccaaggatcc ggacggggcc gtgctggccg ttgcgccggc cgggtgggcg
     1681 gcgctgctcg acggggtcaa ggccgggtcc ttcgacctcg cccgctgacg cgggtttcag
     1741 ggggacggcg cgtgggcgtc cgtccccctg ccctgcgtga ccgccgggtg cggtccggcg
     1801 tcagttcatc gggggctgcc agttcgggtc ggtgacgtcc ttcgggagaa ggctgtcgcg
     1861 gggcgcgttg gtccattcgg ccgtcttgac gatctcgaag tactggcgcg tgcccggggc
     1921 caggccggag ttcttgcgtc ccggcttcac cacgatgccc tggctggcgg tgagccgtcc
     1981 ggtctcgggg tcgatgagga gctgccactc gatcgtgccg tagtcggcgg tggtctgcct
     2041 catcgcgacg cccttgcccg ggtgcccggc ggcgtccgtg ccgttgattg tcttgacgcc
     2101 gcggaggccg gcgagcatcc ggtaggtcgc gatccgcacc cggtcggtga cgacgcggtc
     2161 gaccagcagg atcggggcgg ccgtgaacag gtacaggtcc ggttcgcgca gcggctggtg
     2221 gtcgaacttg gtcgcgtagt tcaggatcca cgcccgcagc ttcgacgggt tcgccgggag
     2281 ccgccgctcg tcctctacgc cgaagtcgag ttcggcgccc tcctgcttga aggggccgcg
     2341 ttcttcgtcg gggccggtga ggtggaggtc ctgggcgccg ggttgaaggt ccgtttccca
     2401 ggccttcttg tcggcgggcg tcgcggggcg gacgtggacg ttcaggtcgt cccaccgcag
     2461 tccggtcgac ggcttcttct cgtgggggag ggtgccgaat tccttcgccg tcttggcacc
     2521 gaggtcgtag gtgtccttgg tgagctgcac ggtgtagtgg acgccggggc gcagcgggga
     2581 cgacgccacg acggtttcgc cgattacccg gtgcacgtac cagaaccgtc cgtccgacgc
     2641 gtgctgggtc ttggcgtcgg cggcggcgag caggaacgtg gacgcggggc cgttctggtc
     2701 ggcgagcggt tcggggtggt agagcgggcg ggtctcccag cggtaggccg tccaggacac
     2761 gccggcgagg acgcatgcgg tggccgccgc gacgagcgtc acccaccgct tggaccgggg
     2821 gagcggcgcg acgcggcggt tccgggcgcc gggcccggtg gcctcggcca ggaggcggcg
     2881 gcgggccgcc cgggccgtct cgggggacgg ggggcgttcg gcggagtgca tccgccggat
     2941 gagggtgagg tcatccatgg tcgtcctcct cgtcgtgtcc cgatgcgcgc agtgccgcgc
     3001 ggacctgttt gcgggcgcgg ctgagccgcg agcagaccgt gccgtaggcg atcccgaggg
     3061 cctcggcgac ctccgggtag ctgagttcgg cgagcgccac gaggagcagg acgtcgcggt
     3121 cgccgtgccg cagccgcgcg agggccgggc tcagcccgaa gctcgcggcc gccaccgcgg
     3181 aggtcacgct gctctcgtgg ctctcgacga cgtcggcggt gcgcatccgg gccatcgcct
     3241 tgtagcggcg cagctcgtcc cggcggtggc ggctgatcag ccgggtcgcg atgccgtaca
     3301 gccagggccg cgccgacgcg tgcgccgtgt cgaacacggc gcggcgccgg aacgcgatga
     3361 ggaacgtctc ggccgcgatg tcgtccgcgg cgtccgcgcc gagccgccgg tccacgtagc
     3421 ggtggatttc ctggtagtgc cggtcgaaga ggtccgcgaa ccgttcgggg tcgcggaggg
     3481 ccgcggtgac gatgtcggcg tcggacggtt cctgctccgc cgatgcgccg gtctgggaag
     3541 gggcgctcgt cacggctcgt cccgcgccgc cggggaagtg gccatgcgga gcccttctcg
     3601 aagcgtggag gggggtcacg tccttgattg cccggtcccg tcccacccct tctcggccgg
     3661 cgcctagagg cagtggccgc tcgcgaggta gggggcggcc cgatcatgcc gcgcacggcg
     3721 agcgcctccc acagcggggc ctgcgccgtc tcggggcggt cggcggccgg cagcacggga
     3781 cgcccgccgg cctcgtcgat ggagacgtcg ccgcgcgcca ggtaccggag tccctcccgg
     3841 ttctgggaga cggcgacgcc cacgacggtt ccggctctgg ttcgctcacc cggcggccga
     3901 ggcggtcgcc ttcgagggac gtcaccgccg acgtccgctc cgccgcgcag ccgagtatcc
     3961 gggtgacggg gtcaccagcg gtcgtggtgg acggcggctt cgagggggcg gcggtggcgc
     4021 cagccgtgcc gttcgagatc cgggacggtc tccaggtggg tgaccggccc gaggcacagc
     4081 caggcgacgg ggcggacgcc cgccgggatg ccgaggaggt cgcgcaggtg cggctcgcgg
     4141 tagaaggaca cccagccgac gccgagtccc tccgccgtcg ccgccagcca cagattctgg
     4201 atcgccaggc agaccgagta caggcccgcg tcggcgatcg cgtgccggcc gaggaccgcc
     4261 gggccgccgc gctccgcgtc gtaggtgacg acgaccgaca cggtcgattc gagcaccccg
     4321 tcgatcttga tgcgggcgaa gcgggcggcg gcgtcgccgg tcagggtggc ggcgaacgcg
     4381 tcccgctcgg accggacgtg gtcgtggaag gcgcggcgga cgtccgggtc gcgcaccagg
     4441 acgaagtccc acggctgcga gaggccgacg ctcggcgcgg cgtgcgcggc ggtgaggacc
     4501 cggtcgagga cgccgtccgg gatcggcgcg ccggtgaact cggcgcgcac gtcgcggcgg
     4561 cggtggatga cgtcgtaaag gttcatgggc aggctcccgc tgcggtcggg ccgcccgggc
     4621 gggcggccgt cggagcgagg ccggtcttcg gactcccgga tcgacgcctc accgcccgcc
     4681 ttcccggccc gaaggccagt ggccgcgcgt gcgcgcatgg gcggcggctc cccggtcacc
     4741 gcggcgggcc cgtgccggat tcgcaccggc ttcccgattc tccccggagg gcacctcgcg
     4801 tcagttcacg ccgtccgcga tcgtagcggc gccgtccgcg cggggccggg ccggggtcag
     4861 cggcgctgga acccgtcctt ggtgcgcagg ccgtagccga cggcgcggtc gatcgagatg
     4921 tgcgccatcc agccgcagag cccggcgaac agcggagccc actgcatcgg cggcgtgacc
     4981 gtgtagagca ccatgaacgc gagcgggacc agcgcgcggt gcgcggcgtt gtagtacggg
     5041 acggcgcgcg ccggaagctg accgggctgc acggtctgcg catcgcgcac cccggccagg
     5101 aaggtcaggt cgggcgcgat gaagaacgcg gcggccacgc cgccggcgac ccagccgtgg
     5161 ttgaccgctt cgaggacggc gaacgcggac cagaacagcc cgttcgccgc ccaggcgccg
     5221 cggcggacgg cggtcgggac gagctgcttg cgggcgtcgt tctcgcgggc ggcgggtgcg
     5281 gtgacggtgc tcatggcctt gacctcctgg ctaatggcgt tagctacaag ctatgactaa
     5341 gggcattagc tgtcaagcta taagcgatcc tgcatcggag ggtgtccggt ccatcgctgt
     5401 acggagtcat gggaaaggcg gcgaaaggga gcttgtcgtt cactagggtc aggtggctgt
     5461 gtcccaatgg agccagcgcg cacagctacg gttatggatc gccgccgtcg cgattaccgc
     5521 ggaaccggtc ctggagaaag ccgccacctc gctgttcggg ccgacgacgt ccagactctc
     5581 cttcggggtc gggatcacca gcatcgatgc ctgccaaggg tggcggcacc agatcgagct
     5641 ctggtccgtc cccggttacc ggctcctgca cacctggccg atcctcgtcg tccttccggc
     5701 gttcctgctt tggctgctgc tccggcaccg cgccgtcgga tgggcggcgg cgctgcttct
     5761 cggagcggtg acgctgcccg aaccggtcct ctacggatac gacgtggcgc gctgggggac
     5821 gcaatgcacg cgaatgtggc tgcctttcgg cagctgggag gtggcgcgct gggttctcac
     5881 ggcggtgccc gttctcctga tcctcgcgtc cacctgcagg cccggccgtc gcaccgtccg
     5941 ccttgtcggc gggacggtcg ccgcggggct cctgctgtcc gtcgcggcgg accgggaggt
     6001 tccgcacagg tacggggcga gtgaggacga atgccggcac gtgaactacg ccgccgcgcc
     6061 cgagcggacg tcctacacgg ccgcgatggc gggtctgtcg cagcgcgaga ggcagatcgc
     6121 cttcctctgc tcgcggcgcg gtttcctgat gggctactcg ggcggaccca tgcgccatga
     6181 ctcgctttcg gacgctgaac agatcgagat ggggcgccgc gcttgccgcg gcgaacggcc
     6241 gatgacgaac ggagtgcggt tgggaatcgc ccccgtctcg ctccaggaca tggcgtatct
     6301 gtgcccagga aaggcggacg aacggcaggc ggtccagcgg cgatccctgg ccgcgctcca
     6361 cgcgaaatac caacgggaaa gggcgaaggc cgaggcgtcc tgccggcgcg gagtcccgga
     6421 ggggttcggc ccggtccgcc aggccacgca cgtcatcgac ggggatgaga gcgggagtta
     6481 cacggtcgag gacgaggacg acggcctcgg cgcctccttc gaccccgcgc tcaaggaagg
     6541 gctgatcgcg agcgcgggcc atggggccac ggtgatcgcg gggaccgagg ggccgctctg
     6601 cctgaccgtc cgtgtgtaca ggaaggcgcc gccggtcgag ccgaggggct gggaccgcgt
     6661 cgaggaggtc ggggtcgaca acccgcacgg gcgggcgcgc ctgatgtcga tggacggtct
     6721 gcttcccttt ccggtggtga acgccgccgg gcccggccgc taccggatcc gcatctacgt
     6781 cagggggagg acggagcccg aggcgttgat ggacgagccg ccgaaagagc accacctgct
     6841 cgtcgtcttc cccggcaagt cggagaaacg gaaggtctac aagaacaccg agcactgacc
     6901 tcgggatcgt ggcgggccgc cgcggaagga cgttcagagg aagagggcgg cgaggcgtgg
     6961 caggtggcgc cggttctcgg cgtcgtcgtc gacgtcccag gtctcgccca gcggttgttc
     7021 gagaccctgc atcgaggcca gggccgcttc caccgccgtg tcgaacgcct cgcgctctcc
     7081 gatgacgcgc tcgtaggctt tgacggccgc gtagagcagg ccctccgcgc ctatccagcc
     7141 cttgtcctcc ttggccatcc gcaccaccgt ggggacgtcg gccagcgagt cggggtcgtc
     7201 gacggcgcgg gtgaacacgt cgcgtcccag cagcgcgagc ccggcgcgga agtccatgaa
     7261 gccgtcgtcg ccgcagccgc cttcgatgag gtaggccgcg ttccagaggg gccgccggta
     7321 cgccgtgtcg aggatccggg tgagggtggc gtcgaacgcg acgatgccgg ggccgtccag
     7381 cgcgaggagc cggtcggtga ccaggccgat cagcgggtcg tcgggggagt cgcggtcgtc
     7441 ggcgtgctcg cccgcctcgg cccgggcgtc ctcgatcaga tcccaccaag cccgctcgtc
     7501 catcggttct ccgcacgcat cggttccgct ttggtggacc aatatcgcgc atgggtccga
     7561 cagaccggca cggaggagat cagagggggc gggcggtgaa ccaggcgccg tcgtcgtcca
     7621 ggaagccgtc gaggcgcagg cccgccgcct ccagcaccgc gggcaggtcc tcgtcgccga
     7681 ggcgccgggt cgtgaaggtg tgcgtccagc ggcgctcgcc gatccggtac tccattgtcg
     7741 ccacgactat cccgggctcc gggcgttcga cgtgcgcctt ccggtagcgg acgccgtcgc
     7801 gctcccactc gcggggcgcg ccgtcgagcc agcggccgtc ggtgtcgcgc tggacgatca
     7861 ccacgccgtc cggccggacg tggcgccggc aggtcgcgag gagggcgtcc cggtcgccgt
     7921 agttgaccag gaacgacatc agcagcacgc agccgaaccg gtcgggcagg tcgagctcct
     7981 ggatgggcga gcagacggtg cgcgcgccct cgatccgggc gagcatcgcc gcggagccgt
     8041 ccaccgccgt caccggatgg ccgaagtcga gcagggggcg ggtgacgcgc ccggtgcccg
     8101 cgcccagctc caggaccgtc gtgccggccg ggatcgccgt gtggacgagc gccgcgctcg
     8161 ggacgtccgg tggcagcgcg gcgtagaact cgaccgccga gccgtcgtcc gcgatctcgc
     8221 ccggacccgt cccggcccgc cgcccgtcct ccgtcgtcat gatcgacatc gtcggacggc
     8281 gccccgctcc cgtcaagccg gccggctccg cggccggaat tgatcaggct gaactggaca
     8341 ggttggcctg aataatttac cctggggcca tgagcgacag cgtcgagccc atctccccgt
     8401 cggccgcccg cgccgcccag gaggtgcggg tcgtgttcag ccggctgcgc cgcaggctgc
     8461 gcgagatcgg cggagcccac gatctcacac cgtcgcaggc ggcggtgctc agccggctgc
     8521 tcaaggacgg cgcgaccacc gcgagcgcgc tcgccgcggc cgagcgggtc cgcccgcagt
     8581 ccatggccgc cacgctcggc gcgctggagg agcgcggcct gatccgccgc gaccccgacc
     8641 cgcaggacgg gcgccgccag ctggtcacgc cgagcgacgc cggccgcgaa tgggtcgagg
     8701 gctcccggca agcccgcgac gaatggctga gccgcgccct ccaggaccac tgcaccgagg
     8761 aggagcgcga gacggtcctg cgggccttca ccgtcctcga ccggctcgtc cagtgagcgg
     8821 gagaggggac gcgcccctct cccgcccccg cgtcaggacg cgggcaggcc gagggcgcgg
     8881 gcgatcagca tccgctggac ctccgacgtc ccctcgccga cctccaggat cttcgcgtcg
     8941 cggtagaagc ggccgaccgc gtactcgttc atgaagccgt agccgccgaa gacctgcgtc
     9001 gcgtcgcggg cgttgtccat cgccgcgttg gacgcgacga gcttggcgat cgccgcctcc
     9061 ttcttgaacg gctcgcccgc cagcatcttc gccgccgccg cgtagtaggc gaggcgggcc
     9121 gtgtgcgcgc ggacctccat gtcggcgatc ttgaactgca tcgcctggta gcggccgatc
     9181 tccttgccga acgcctgccg ctcgccggcg tagcgcaggc actcgtccac gcagccctgc
     9241 gccaggccca ccgacagcgc ggcgatcgcg atccggccct cgtccaggat ccgcaggaac
     9301 tgcgcgtagc cccggccgcg ctcgccgacg aggttctccg ccgggacccg gacgtcgtcg
     9361 aacgccagct cccgggtgtc cgacgacgac cagccgacct tggagtactt gcggccgacc
     9421 gtgaaccccg gcgtgccgct cggcacgatg atcgtggaga tctcgccgtc gccggtgaac
     9481 gcggtgacgg tcacgaacgc ggtgatgtcg gtgccggagt tggtgatgaa cgccttcgac
     9541 ccgttgatca cccacgagtc gccgtccagc cgggccgtgg tgcgcatccc gccggggacg
     9601 tccgagccgc cgcccggctc cgtcagcccg aaccccgcga gcttctcacc ggacgtcagc
     9661 atcggcagcc agcgcgcctt ctgctcgtcc gacccgaacc ggtagatcgg catcgcgccg
     9721 agcgagacgc ccgcctccag cgtgatcgcg accgacgagt cgacgcgcgc cagctcctcc
     9781 agcgccaggc agagcgcgaa gtagtcgccg cccatcccgc cgtgctcctc ggggaacggc
     9841 agcccgaaca gtcccatctt gcccatcgcc gcgacgatgt cgtacgggaa ctcgccgcgc
     9901 tcgtacaggt ccccgatcac cggggcgacg gtctcgcgcg cgaaccgctc gacggtccgc
     9961 cgcagctcct cctgctcgtc gctgagcttg aaatcgatca tcatttctcc gttgcgggtg
    10021 acagggcctg gacgacgcgg gacgggctcg ggcggccgag ccgctcggcc atccagcggc
    10081 tggtggcggc gagcgccgcg aggtcgacgc cggtctcgac gccgaggccg tccagcatcc
    10141 agacgaggtc ctcggtgggc aggttgccgg tggcgctctc ggcgtacggg cagccgccga
    10201 ggccgcccgc cgaggcgtcc acgacggtga cgccggcgcg cagcgcggcg agggtgttgg
    10261 cgagcgcctg cccgtaggtg tcgtggaagt gcacggcgag gcggtcggtg ccgatcccgg
    10321 ccgcgaccag cgcctcgatc agcgcggtga cgtggcccgg cgtgccgacg ccgatggtgt
    10381 cgccgaggct gagctgcgag cagccgagat ccatcatccg ggtcgcgacg gacacgacct
    10441 gctcgatcgg gacgtcgccc tcccacgggt cgccgcacac catcgacaca taggcgcgca
    10501 cccacaggcc ctcggcgcgc gcgcgttcca cgacgggcgc gaacatcgcg agcgactcgt
    10561 ccacggtccg gttgaggttg cggcgggcga acgtctcggt ggcgctcccg aagatcgcga
    10621 tctcggtgat gccgttggcg agcgcccggt cgaggccccg ctcgttcggc accagcaccg
    10681 ggtaccgcag attccccgag cgcgggagca cgccgagcag ctcctcggcg tcggcgagct
    10741 gcggcaccca cttcggatgc acgaagctcg tcgtctcgat cgtggtcagc cccgcgccgg
    10801 cgagccgggt gacgaactcc gacttcacct cgaccgggac gatcgccttc tcgttctgca
    10861 gcccgtcccg cggcccgacc tcgtagatcg tgacccggtc gggaaggccg ggcagcggtg
    10921 tcgccatcat gcctcctcga tcacggccag caccgcgtcc agggcgacct gggcgcccgc
    10981 gcgggccggc aactgcgcca cgacaccggc gcgcggcgcg gtgacggtgt gctccatctt
    11041 catcgcctcg acgacgacga gcggctgtcc ctcgtccacc cggtcgccct cgccgacctt
    11101 cacggccagg accgtgccgg gcatcgggct gcgcagcacc ccgtcgccgg acgcgtccgc
    11161 cgcggcgccg ccctccgcct tgacgtgctc ggcgagcgcc cacacgtggc cgccgcggcc
    11221 gagccacagg gtgcggccgt cgcgggccgc ggtgaacgag accgtccggc cgccgtaggt
    11281 gagggccgtg ccggtgagcg acgcggcgac cggctcgccg tcgccgatcg cgacccgcgc
    11341 ggccgcggcg cggccctgca cgcggacctc gacgggctcg ccgccggacg gggtgatgat
    11401 ccacggcgtc caggcgtgcg cgccggggcg ccagccgtcc gggatcgccc acgggtcgcc
    11461 gtcggcgggt tcgagggcga gcatccggtc cagcgcggcg gcggcgagca cctccggcgg
    11521 cacgccgccg tccgaggtca gctcgtcgag cgcgcgttcc accaggcccg tgtcgaggtc
    11581 gccggacgcg acggacgggt gcttcagcag cgcgcgcagg aacgccacgt tcgtcgggac
    11641 gcccagcagc gtgtacccgg cgagcgcgcg gtcgagccgg tgcagcgcct ccgtgcggtc
    11701 cgcgccgtgg acgatcacct tcgccagcat cgggtcgtag gacccgccga cctccgtccc
    11761 gacgccgagg cccgagtcga cgcgggcgcc ctccggctcg tcgagcgcga ggacggtccc
    11821 gccggtcggc aggaagccgc gcgccgggtc ctcggcgtag acgcgcgcct cgatcgcgtg
    11881 cccgtccagc cggacgccgt cctgcgcgaa cggcagcggc tcgccggacg ccacccgcag
    11941 ctggagttcg accaggtcga ggccggtgac cagctcggtg acggggtgct cgacctgcag
    12001 ccgggtgttc atctccatga agaagaactc gtcggggcgg tcggcggaca cgatgtactc
    12061 gaccgtcccc gcgcccacgt acccgaccgc ctgcgcggcg gcgacggccg cggcgcccat
    12121 ccgcgcgcgg gacgcctcgt ccagcagcgg cgacggcgcc tcctcgacga tcttctggtg
    12181 ccggcgctgc aggctgcact cgcgctcgcc caggtggacg gcgttgccgt gcgcgtcggc
    12241 gaacacctgg atctcgatgt gccgcgggtt ctccacgaac cgctcggcga gcagggtgtc
    12301 gtcgccgaac gagccgcgcg cctcgcgacg ggcggacgcg atggcgtccg gcaggtccgc
    12361 cgcgtcgcgg acgaggcgca tgcccttgcc gccgccgccc gccgacggct tgagcagcac
    12421 cggcagcccg acctccagcg cggcggcctc cagctcggcg tccgacaggc ccggttcgtc
    12481 ccgtccgggg acgaccggga cgcccgccgc cgcgacggtc cgcttcgcgc ggatcttgtc
    12541 gcccatcgcc tcgatcgcgg acgcgggcgg cccgatgaac accagcccgg cgtcggcgca
    12601 cgcccgcgcg aacgcggtgt tctcggccag gaacccgtag ccggggtgga cggccgccgc
    12661 gcccgacgcc cgggccgcgc cgatgaccgc gtcgacgtcg aggtaggacg ggatgcggag
    12721 cgcctcgtcg gcctcgcgga cgtggcgggc gcccgcgtcc gcatccgtgt ggacggccac
    12781 cgcgcggatc ccgagccgcc gcagcgtgcg gaacacgcgg acggcgatct cgccccggtt
    12841 ggcgaccagg acgctgtcga acatcgatgc cccgcgccgg gaaggcgccg tggctccgtg
    12901 ccgggaagac attgggcccc tcacatccgg aagacgccgt agccgaccgg ctccagcggt
    12961 gcgttggcgg cggcggacag cccgaggccg aggacgcgcc gggtgtcgag cgggtcgatc
    13021 accccgtcgt cccacagccg ggccgtcgag tagtacgggt tgccctgcgc ctcgtactgg
    13081 tcgcggatcg gcgccttgaa cgcctcctcg tcctcggccg gccagtcctc gccgcgggcg
    13141 tccatctggt cgcggcggac cgtcgcgagc acgctcgcgg cctgctcgcc gcccatgacc
    13201 gagatccggg cgttcggcca catccacagg aagcgcggcg agtacgcccg gccgcacatc
    13261 gcgtagttgc ccgcgccgaa cgacccgccg atgacgaccg tgaacttcgg gacgcgcgcg
    13321 cacgacacgg ccgtgaccat cttcgcgccg tgcttggcga tgccgcccgc ctcgtactcg
    13381 cggccgacca tgaaaccggt gatgttctgc aggaacacga gcgggacgct gcgccggtcg
    13441 cacagctcga tgaagtgcgc gcccttctgc gccgactcgc cgaacaggat gccgttgttg
    13501 gcgacgatcc cgaccgggtg cccgtggatc cgcgcgaacc cggtgacgag cgtcgcgccg
    13561 tactccttct tgaactcctg gaaccggctg ccgtccacga tccgcgcgat gacctcgcgc
    13621 acgtcgtagg gggtgcgcgg gtcgggcggg acgaccccgt acagctcgga cgggtcgacc
    13681 gccggctcct ccggcgccgc cacgtcccac gggcgcggct cgcgcgggcc gagcgtgccg
    13741 acgatgtcgc ggacgatccg cagcgcgtgc gcgtcgtcct cggcgaggtg gtcggtcacc
    13801 cccgacgtgc gggagtgcag ctcgccgccg cccagctcct ccgccgtgac gatctcgccg
    13861 gtcgcggcct tcaccagcgg cggcccgccc aggaagatcg tgccctggcc gcggacgatc
    13921 accgcctcgt cgctcatcgc cgggacgtag gcgccgcccg ccgtgcacga gccgaggacc
    13981 gcggcgatct gcgggatgcc gcgccccgac atggtggcct ggttgtagaa gatgcggccg
    14041 aaatgctcgc ggtcggggaa gacctcgtcc tggcggggca ggaacgcgcc gccggagtcg
    14101 accaggtaca ggcaggggag gcggttgtgc agggccacct cctgcgcgcg cagatgcttc
    14161 ttcaccgtga ccgggtagta cgtcccgccc ttcacggtgg cgtcgttggc gacgatcacg
    14221 cactcgcggc cggacacccg gccgacgccg gtgatgatcc cggcgcccgg cgcctcgtcg
    14281 ccgtacatgc cgttcgccgc cagcggggac agctccagga acggcgagcc ggggtccagc
    14341 agcgtgtcga cccggtcgcg ggggagcagc ttgccgcgcg ccacgtgccg ctcgcgggcc
    14401 cgctcgggac cgccgcggcc ggcccggtcg acgcggtcgc gcagctcggc cgccagcgcc
    14461 tcgttgtgcg cggcgctcgc cttgaacgcc tcgccggcgg cgtcggcgag gctgccgatc
    14521 tcgggtccgc tcatggtccc cttcccagtt aatgctcgtt aacaacgccg atgttagaga
    14581 tgttaatacc cattaacaag tctggtctag actctccccc atgacctcct acccggccgc
    14641 ggcgcccggc gacaccggcg gcgagccgcc cgtcgccgcg gtgaacccgc gccgcgccga
    14701 gatcctcgcc gccgcggccg agctgttcgc ccgccgcggc taccacgggg cctccatcgg
    14761 cgacgtcggg cgggccgtcg ggctcaccgg ccccgccctc taccggcact tcagcggcaa
    14821 ggaggccgtc ctcgccgaga tgctcgtcga catcagcgag cggctgcacg ccgagggcgt
    14881 ccgccgcgcc gccgaccccg accccggccg cgccctcgac gcgctgctgc gctggcacat
    14941 cgccttctcg ctcgacaacc ccgcgctcat caccgtccac gagcgcgaac tcgacaacgt
    15001 ccccgagccg cagcgtcacg aggtccgccg gctccagcgc gcctacgtgg aggaatgggt
    15061 cggcgtgctg cggcggctgc gccccggcca gcccgacggg cgcacgcgcg ccgccgtcca
    15121 cgcctgcttc ggcctgctca actccacccc gcgcagcgcc gccggcctcg accgcgacgc
    15181 gatggacgac ctcctgcgca ccatggcccg cgccgccctg gaagccgcct gacgggacgc
    15241 gccgccgccc gcccgccccg gaccgggcgg atcacggacg gcccgcaatc ttgacgcgcc
    15301 gccgctcagg tgggtcatat gggatgaaag gtcacccggc catcccaccc cgccgcagag
    15361 gagagccgca tgggcgtaca gggcgtcggc ttctacgaga tcgcgagcaa cgacccggac
    15421 cgccccgcga tcctggcccc cggcgtcccc gtctcctacg gcgagctgca cgccgaggtg
    15481 aaccggctgt cgaacgcgct ggacggcctc ggcctgcgcc ccggcgacgc cgtcgcgacc
    15541 gtcctcggca accgccccga gttcctcacc gtgctgctgg cggcgatgca gtccgggctc
    15601 tacatcgtcc cggtgagccg ccacctgacc gcgcccgaga tcggctacat cctcgccgac
    15661 tgcggcgcga aggccgtcgt gaccgagagc gcgttcgcgc cgaccgtcgc cggcgccgcc
    15721 gacaaggccg ggatcgccgc ggacctgcgc gtcagcgtcg accccgccga cggccaccgc
    15781 tccatggccg cgctgtgcgc gtccggcagc gccgagccgc ccggcaagcg gcggatgggc
    15841 tcgatcatgc tctacacgtc cgggaccacc gggcgcccca agggcgtgcg gcgcccgctg
    15901 ctggacgtcc cgccggaact gctcttcgac atcatgcgcc ggacgctcgc gacccacctc
    15961 ggcctcgaac ccggcgacga ggtgcacctg gcgatcgggc cgctctacca ctcggcgccc
    16021 tgcgtgcacg cgatgatggc gctcaacctc ggccacgccg tcgtcgtcgc gtcccggttc
    16081 gagcccgagc agacgctcga gctcatccag cggcacggcg tcaccaactc gttcatggtg
    16141 ccgaccatgt tccaccgcat gctcgccctg cccgacgacg tccgcgcacg gtacgacctg
    16201 tcgtcgctgc ggcaggtgta ccacagcgcc gcgccgatcc ccgtcgagac caagcagcgg
    16261 atgatggact ggtgggggcc cgtcctctac gagtactacg ggtccaccga gagcggcgcc
    16321 gtcgtcgtcg ccaccccgca cgactggctc gcccgccccg gcacggtcgg ccgcgccgtc
    16381 gacggcgtcc ggatcaggat cctcgacccg gagggcgcgg agctgccgcc cggcgagacc
    16441 ggcctcatct acgccgcggg acagcccggc ttcgagtacc acggcgaccc ggacaagacc
    16501 gcctccacca tgcgcggcga gttctacacc cccggcgacc tcggccacct cgacgaggac
    16561 ggctggctct acatgagcga ccgccgcacc gacctcatca tctccggcgg cgtgaacatc
    16621 tacccggccg agatcgagtc cgtgctgctc cagcacccca ccgtcggcga cgtcgtcgtc
    16681 atcggcgtcc cggacgagga ctgggggcag cgcgtcgtcg ccctcgtcga gcccgcggac
    16741 ggcgccgtcg ccggcgacga cctcgccgcc gacctgctcg cgcactgcga gccgcgcctc
    16801 gcccggctca agcatccgcg ccggctggag ttccgcgcgt cgctgccgcg caccccgtcc
    16861 ggcaaactca gccgcagccg cgtgcgggac gcctacctgc gcgaacaggc ggggtaggcg
    16921 gctccgggcc gcgcacgggg gagggccgcc gcacgccgct gccgagaccg tcgaacgatc
    16981 ccggggcgcg ccgcgtacaa cggcacatgg aagaccagaa ggtcgccccg ctcgacaacg
    17041 ccccgacccc tgccgccccg acgttgaccg accttcccgt gatcacggac cccggcttct
    17101 acaccgaccc cgcgtactcc gcgcagagcg tcccgcccga ggacgccgcc gcccccggca
    17161 ccgggctcga caccgtgccc cgcgccggga ccgcccgccc cggcggcccc gtcgcggtct
    17221 ggccgtgcgc cggctgcggc aggcccgtac cgcagccggt gcgcggcgcc cgcaccgtcc
    17281 gctactgcca ggacgacggc ggcgcgtgcg agcgcgccgc gcacgagcag cgcgaacgcg
    17341 cccgcgagac ccccggcctc accggccagg tcgcctggac gtgggagatg gtcgaacggc
    17401 tggaggccgt cgccgaccgg ctcgccggat cgctggtctc cgagctgggc gtcgccggcg
    17461 tcgagcggcg cgtcgccgac gcccgcgccg acgccgccgg gcagatcgcc gtcgcccagc
    17521 gcgagcgcga cgcctcccag cgccaggccg aggccgcctg gcgcgagacc gcggccgccc
    17581 gcgcccgcgc ggacgccgcc gagggcgagg ccgccgcggc ccgcgccgcc gccgagcagg
    17641 ccgccgccga acgcgacacc gcccggcgcg ggggacagga cgccaaggac accgcggacg
    17701 ccgccgtcgc cgcgcagctg gccgccgaac gcgaacgcga ccgggtcgcc tcccgcgagg
    17761 gcgagctgct cgccgcgctc gagaccgccc ggaccgagct cgtcggcctg cacggccggc
    17821 tgtcggaggc cgagaccctc gccgaggggc agcggatcga ggccgccgcc gcccggcgcg
    17881 ccgccgacga cctgcgctcg gccgtccgcg acgccgagac ccagcgcggc caggccgtcg
    17941 ccgaccgcga ccagatccag gcgcgcgccc gcgacgtcga cgagcgcaac cgggacctgt
    18001 cgcgcgccaa cgaggagctg cgcgccgccg tccagaccct caccgccgaa cgcgacgccg
    18061 cgcgcgccga ggccgaccgc gcccgccgcc gcgtcgacgc gctcacccgc ccggcggacc
    18121 cgcgcccgga cggccggccc gccgccgacc gggaaccgct gaccggcctg caccccctgc
    18181 ccccgctgaa cgggtcgcgg ccgaacgggt cctccctcga cggaaccgac cccctcgcgg
    18241 tcaacgaaca ccgccttccc cacgccggct gaccaccggc cggcgaaccg acgacgagga
    18301 ggtgaggccc ttcacccaca cggcactggc cctgaaccgg ccgccgcacc gcaccggggt
    18361 ggtggggcgg ccggtacgcc aggctaggac ggccgggtgc gcaggtactc ggtgtagtcc
    18421 agcgcgcccg cgcggaccgc cgcgtgcacg gcgcgcgcga tccgggcacc ccatgtcgaa
    18481 cggggcccgg cgaacggctc ctgcgcgccc gaggcgcgcg ccgccacgca gatcgcgtcg
    18541 gacgcggtgc ccgtgcacgg gtagcccgcc tccaggagcg cctgcgtctt ggcctccgtc
    18601 gcggtcacca cggcgttcac cagcgcggcg tcgctcaacg ccaccggaac cgcgactacg
    18661 atgttgatcg ttcccggccg ccgggtcgcc tccggcgcgg gctccggcgc cggcggcggc
    18721 acggccatgt ggagcggcgc cagctccgga tcggcggacc cctccggcgc cgccgcccac
    18781 gtcggcacgc ggagcccgac cgtcgccgac accgcgacac cgccgtcctc gcggcgcatc
    18841 gtccgcgcga cggacgccgc cgtcagcatg ccgacacccg ggccgtcgag cccgaacgac
    18901 gcggccagct ccgccaggtg gacgaccggg tccgtccgcg cgtaccggcc gcggacctgc
    18961 gcgttcagcg cccagttcag gggcccgatc ccgccgccga gcatcgccga cgacaccgcc
    19021 cgccacccgc cgcccgcgcg ccacaccgtc gcggcgagcc gcgcgccgtc ctcgtcccgc
    19081 cagatcgtct cgatgttcac gggcgctcca gcgacagcag gggccggccg tccggcccgg
    19141 gaaggacgtg cacgcgggcg tcgaagtgct cctggatcgc cgccctggtc agcaccgtcg
    19201 cgggcgcgcc cgccgccgcg acccggccgc ccgacagcag caccaggtcg tcggcgtact
    19261 gcccggcgag cgtcaggtcg tggatcgtcg tcacgaccgt cagcccgtcc gacagccgca
    19321 gctggtcgat cagctccatc acctgctgct ggtgcccgat gtccagcgcg gtcgtcggct
    19381 cgtccagcag cagcaccgac gtctgctgcg ccagcgcgcg cgccagcacc acgcgctgcc
    19441 gctcgccgcc ggacagatgg tccagcggac ggtccgccag cccggtcaga tcgaggcggt
    19501 ccaggacctc gcccgcgatg gcgcggtcgc gcgcgctctc ccggcccaga tgcgggatgt
    19561 acggcgaccg ccccagcagc gtgtagtcga acaccgtcat cccgaccgga aggttcgggc
    19621 tctgcggcgc gtacgcgacc agccgggcgc gctgccgcgg cttcatcgcc gccaggtccg
    19681 cccccgccac gccgatgtcg cccgcgcacg gcagcagccc gagcaccgcc cgcagcagcg
    19741 tcgacttccc cgccccgttc ggcccgatca ccgccgtcca cgaccccgcc gggacctcca
    19801 gcgacacccc cttcagcacc ggacgcccgc ccagcgacac gtccaggccc cgcaccgaga
    19861 ccgtcacgtc tccacctgcc gccggctcgc ccgcagcacc gccacgaaga acggacctcc
    19921 gacgaacgcc gtcaccacgc cgagcggcag ctcgcccggc gcgatcaccg tgcgggccac
    19981 caggtcggcc agctccagga acgccgcccc gccgagcagc gacagcggca gcaccacccg
    20041 gtacgacccg cccgccagcc gccgcaccgc gtgcggcacg acgatcccga cgaacccgat
    20101 caacccgctc accgccaccg cggtcgccgt cgccagcgac gccgccacca gcaccgtcag
    20161 cctgacacgc gccgccgaca atccgagcga cgccgcctcc tcgtcgccga cgctcagcac
    20221 gtccagcagc cgcccgtgcg cgagcagcac caccgtcgag accagcgagt acggcgcgac
    20281 gagcgccagc tggtgccagt ccgccgaacc gacgccgccg aggatccacg agtagatccg
    20341 ctgcagctcc tccgccttca cctgctgcat gaacgtctgc accgccgaca ggaacgacga
    20401 caccgccacc cccgccagca ccagcgtcgc cgcccggttc ccccggcccg ccgcgctgcc
    20461 cagcgcgtac gccatcgcca ccccgaggag cgcgcccgcg aacgcggcca gcggcacccc
    20521 gtaccccggg tcgcccggca ccaccacgat caccagcgtc gccccgacgc ccgcgcccgc
    20581 cgccgcgccg agcaggtacg gatcggccag cggattgcgg aacaccccct ggtatcccgc
    20641 gcccgccatc gacagcatcc cgccgaccag cgccgccatc agcacccgcg gcacccgcag
    20701 ctggaacagc acgttctcgt cgaccacgct gaacccgctg tcgacgtgca cgaacgggac
    20761 cttgtcggcc agcgccgcca ggatcccccc gaccggcagc ccggccgcgc ccaccacgag
    20821 gcccgccagc agcgtcgccg ccagcagcac cagcgccacg accagcggca acggccgcaa
    20881 ccgcccccgc acccgaggcc cggcgccccg ctcggccgcg aggacgtcgc cgcgccgtcg
    20941 cgcggagacg tcctccgcct tcttcgggac gtcctcagcg tcctgcggga cgtccttcgc
    21001 gtcctgcggg acgtcgctct tgtcttgccg gatgtcttcc gcgtcccccc ggacgtcctg
    21061 cgcgccctgc gagacgtcct tcgcgtcctg cgggacgttc tccgcgttct gtgggacgtc
    21121 cttcgcgttc cccgggacgt ccttgacgtc ctggaggacg tccgtcgtgt cctgcgggac
    21181 gtcctgcttc cgcgcctcgg ccctctcggg acgtgccggg acgtccccgg gcgcgtcctc
    21241 gcggacggcc ggggacggct cgcggtcggg gggcctcacg ggcggggggc cttcagggcg
    21301 gcggtcaacg cgtcttctgc accgcgtcgc cgatcgcctt cacgaactgc ggcaggcgcg
    21361 ggccccagcg ggaggcgagg tcgtcgtcca gcggcaccac gccgccgtcc ttgacggcct
    21421 tcaggtcccc gaagccgggc cgcttggcga gcgcggcggc gttctgcccg cagcacttgg
    21481 tgtcggccag gaagatcagg tccgggtcct tcttgacgag gtactcgcgg gacagctgcg
    21541 ggtacccgcc gctcgccttg tccgccgcgt ccgcgacgtt gcgcaggccg aacaggccgt
    21601 acacctgccc ggcgaacgtc tgcgacgtca ccgtgtggag ctcgttgtcg agctcgtggt
    21661 agtaggtgag gcccttgccc ttggtggacg cggcgacggt cttctggatg tcggcgcgca
    21721 tcccgtcggt gaccttcttg gcctcggcgg cgtgcccggt ggcgaggccc aggtcggtga
    21781 tctcgtcgta ggcgtcgtcg agcttctccg cggccggctc cagcagcacc gggatcttga
    21841 ccttctccag cgccttgacg acgccgtcca tgtcgttgga caggacgacg aggtccggcc
    21901 ggtacttgat gaccgcctcg gcgttcggct tgaagccgga cagctgcgtg cggggcgcgt
    21961 tcgaggggta gtccgacagg ccgtcgacgg cgacgacctg ggagccggcg ccgatcgcga
    22021 acagcgtctc ggtgtgcgtg ggggacagcg acacgatccg cttcgggtgg gcgggaacgg
    22081 tcaccgcgcc gttcccggcc tggacggtga cggtcttcgc gccgtcgtcc gccgtcttgg
    22141 tcttgccgtc gccgccgcat ccggcggcga gcgtcacggc ggcggtcacg atggccgcgc
    22201 cgaggacgcg cacgggtctc acaggagcct cctggctgca gggaagccgc ggcccgtcat
    22261 gacggatcgc ccttccacga ggtcgagagt cgtcggcgcg cgcggaggcg acctggctcg
    22321 gcctcttcga caggggcacc acagttgcgg gacagcgccg ggttcacacc ggacttcgct
    22381 ccagggcgcg cttgaagtgc aacggtatca gccgccttat ccggtttcgt gtgagcaccg
    22441 gagtgagtac tcacttcggt attgacggag tgagtactca ctccgtactg tggcgggcat
    22501 ggagtccgag aaccgccggc gcgcccccgg gatgagtccc gagcagcgcc gggagatgat
    22561 cgtcaggacc gcgctgccgc tcgtcgccga gcacggcacc gccgtcacca ccgggcagat
    22621 cgcccgcgcc gccggcatcg gcgaggcgac gatcttccgc gtcttcgccg acaaggacga
    22681 gctgctcgac gcctgcgtca tggaggcgct gcgcaccgac cacgtgctcg ccgagatcca
    22741 ggagatcccg ctcgaccagc cgcttcccgc ccgcctcgcc gaggccaccg ccgcgatcga
    22801 ggcctacctc ggccgcatgg gcatgatcct cggcgccctg cacgccaccg gacgccgcgg
    22861 gcgcggctcg cacggcggcg gcgaggcggc cgacgccgcg atcgaccgcg cgtccgccat
    22921 ggcccgcacg cgcggcgcgc tcgccgagct cttcgaaccc gaccgcgacc ggctccggct
    22981 gcccgccgac cggctcgccg ggatgttcat ggggctggtg ttcacccgca gccgcccgcc
    23041 gggcggcccc gagacgccgg cgccctccct ggaggagtac ctggaggtct tcctgtacgg
    23101 cgcgctcacc ggcacgaccc ccgaagggag caccgaatga ccatcaccct caaccacacc
    23161 atcgtcaccg ccgccgacaa cgacgaggcc gcccgcttct tcgccgccgt gatggggctg
    23221 gcgtacaccg ggccccaccc gcacgctcgc cacttcgtcc cgatcaaggt caacgagggc
    23281 ctcaccctcg acttcatgac cgtcgcgttc ccgcagggcc accatctggc cttcgacgtg
    23341 gacgccgcca cgttcgacgc ggtcctcgac cgcctcgacg cccgcgagat cccctacggc
    23401 gaccaccccg cgcaccccga caacggccgc gtcgacaccg cccacccgct cggcgggcgc
    23461 ggcctgtact tctccgactc ctgcggcaac ctctacgagc tgatctcgtc ctgaggccga
    23521 cccggcccgg tcggggcgcg ccgggtcagg acgcgaacga ccgcaggaag gcgcgggtgc
    23581 gggtccggtc gtcgccgggc atgaactcgc ccgccacgaa ctcggtgacg cccgcggcgg
    23641 ccaggtcccg gatccgcgcg ccgaccgcgt cctcgtcgcc gatgatcgcg aggtcggcgg
    23701 ggccctcggc gccctcccgg tccatcatcg cgcggtagga cggcagcgtc ccgtacacct
    23761 cgaacgcctt cgccgcgcgc tcgcgggccc gctccacgtc gcccgtgacg cacaccggca
    23821 gcacgcacac gatccggggc gcgggacggc cggccgcctc cgcggccgcg gtgatggtcg
    23881 gcgcgatgtg gtcgcggacg gtggccgggc ccgtcatcca caggacggtc ccgtccgcgc
    23941 gctccgcggc gagcttcagc atcttcgggc cgagcgccgc cagcagcacc gggacccggc
    24001 cctcgttcgg cacggtcagc ccgatctggc cgcgcagcgt ctcaccggtg aacgacgccg
    24061 tctggtggtc gagcagcggc agcagtaccg acaggtactc gtccatgtgc cgcagcggac
    24121 ggccgaagtc gtacccgtac atctcctcga tgacgacctt gtgcgacagg ccgatgccga
    24181 gggtcagccg tccctcgccg agcgcgagcg cgacggtccg cacctgctgg gccagcgccg
    24241 ccgggtgccg cggatacgtc ggcaccacgg cggtccccag ctcgatcccc ggcacccggc
    24301 tgcccgccac cgcgagcgcg gtcagcgcgt ccacgccgaa gatgttcgac atccacgccg
    24361 aggcgaaccc gtcgtcggcg gcgcgccgca cgtcgtcggc cagcttgtcc agcgcgccgg
    24421 caccgccgcg ctcgccgagg gaaacaccga tgcgcacaac gacctcccag gtcagcgtcc
    24481 tgctccgatc gtcgcacaga gcgtggtcag ggccgccggg cggggtcgtg ggcggcgcgg
    24541 tcccgcgcct ccatgaagaa gtcgtgcagc gccgtcgcgc cgggcaggag ccggacgggc
    24601 cgcgccgcgc cgaccgaggc gttccagaac gcgccctgcc tgggctccca cggaccggcg
    24661 tacgcgtacg gctcgccgag gaaatcgtcg ccgggggata tgccgtaatt gacctcgtcc
    24721 agggtgatgg ccaggtcgaa atgctccggc cacagcacgg gcgcgacatc cggcgcgagc
    24781 cggaccaggg cctcgttgcc gcgtgcgaag cactcttcga ggtgggcggc cgcgcccgcg
    24841 tccacgtcga gcgtctcgtc cgcgccgact ccgctgccgt ccttgtaaag gccttgcggg
    24901 gcgcccgcct cgacgtcggc cgccgtggcc agttccccgc acgtcgcgcc gttcagcggg
    24961 atcgtcctgt ctccggcgac gagctcggcg cccgcaaccc gcagaaccgg tgcgctgacg
    25021 gtcgcgaacc cgtcggccag cacgcgcagg cggatcgtcc cgctctcccg gtactgcggt
    25081 ccggcgagca gcagttccgc ggcgccgtgc agcgaccggc gcgtcgttcg aagaatctcc
    25141 ggatccacgg tcatgtccac ttccctcgcc tgccgccgcc gatgactgcc ccggtgtctc
    25201 accctgcgcc ccaagggcgt ccctcacaaa ccgtccgggt caccggagtg cggcccgtag
    25261 cgctccgcca ggtcccggtc gttctccgcc caccggcgat gccgctcggc cgtctccaga
    25321 tgcgccgcgg cctcgtcggg atggacggcc gccatgtcct ccagcaggtc cgccgcccgg
    25381 tcgtgcgccc acgccgacga cagcatggac cgcagtgcgt actcgccggc accgcgccgc
    25441 ggcgaacgcc cgggacgcgt gccggccttc ttcgcgggcc gctgccccgc gtcggaggcg
    25501 tcccgcggcc aggcggcccg ggcatcccgc ggcttctcgc gcgccgtcag gcgcagcgcg
    25561 cggtcttcgc cgtccatacc ggccgaaccg acccgcgcgc ccgtgacccg accagcgtcc
    25621 cccgcacacc cgctccctac ccacccacct gcacgttcag ccccatccgc cgcacttctc
    25681 cggcggggcc ggatgagatc cctgagcgcc atgaccgatc atggaagggt gactccggac
    25741 cccgtgaccc ttcacgccgc cgacggtgtg cggatcgacg ccggacacct cggcggcgac
    25801 ggcgacctct gcttcgtgct cgcgcacggc ttcacctgct cgtggcggca gcccgcgctc
    25861 cgccgcatcg gcgcggtcct gcaccgctac ggcggcgtcg tggccctcga cctgcgcggc
    25921 cacggacgct ccggcgggca ctccaccgtc ggcgaccggg aggtcctcga cgtgcaggcc
    25981 gcggtcgccg ccgcgcgctc gcgcggctac cggcgcgtcg ccgtcgccgg cttctcgctg
    26041 ggcggcgccg tcgccatccg gcacgccgcc ctgcacggcg acgtcgacgc cgtcgtctcg
    26101 gtcagcgcgc ccgcccgctg gtactaccgt gacaccgtcc ccatgcgccg cgtccactgg
    26161 gtcatcgaac agcccctcgg acggctcgcc gtccgcctgg cccgcggcac ccgcatcgcc
    26221 gccaagggct gggaccccgt ccccgaggcg ccccacgagg tcgccgcgcg catcgcgccc
    26281 gcgccgctgc tcatcgtcca cggcgacgcc gacgcgttct tccccaccga gcacggatgg
    26341 cagctgtacg acgcggcgcg cgacccgaag gagctgtgga tcgaaccggg cttcggccac
    26401 gccgaggtcg ccgcgacccc ggacctcatc caccgcatcg gcgcctgggc cgcgtccgcc
    26461 gccaccgtca tgcgccccga cgcgaccctc tgacgtcagc gctcccgccg cttatcggcg
    26521 aggccgtcga cgaggctccg cagcccgaac ccgaaccggt cggtgaggcg cggcgcgagg
    26581 agcccgcccg cgaccgccac caggtcggga tagcggtcgg cgggcagtcc ctccaggtag
    26641 cggcccacct cggcgagccg gtccccgttc tccggaccct tgccgaacgc gatctcctgg
    26701 acggcgaagc ccgtcacgta gaacatcagc agcaggtacc cgtagcccgc catccggtcg
    26761 tcgaagccgg cgcggcgcag catgccgatc acgcggtcgg cgaggcgcag cccgttggga
    26821 ccgaacggga gccggcccgg cagcagccgc gtcgccgcgg gatgcgcgag cagcacgccg
    26881 cgcaggtcga ggccgacctc gatgagccgt tcgtccc
//
