LOCUS       NZ_CP053892            21038 bp    DNA     circular CON 05-MAY-2024
DEFINITION  Actinomadura verrucosospora strain NRRL:B18236 chromosome.
ACCESSION   NZ_CP053892
VERSION     NZ_CP053892.1
KEYWORDS    RefSeq.
SOURCE      Actinomadura verrucosospora
  ORGANISM  Actinomadura verrucosospora
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 10214634)
  AUTHORS   Samborskyy,M.
  TITLE     Actinomadura verrucosospora NRRL-B18236 (PFL_A860) Genome sequencing
            and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10214634)
  AUTHORS   Samborskyy,M., Dickens,S. and Scott,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAY-2020) Biochemistry, DNA Sequencing Facility,
            University of Cambridge, 80 Tennis Court Road, Cambridge,
            Cambridgeshire CB2 1GA, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-DEC-2016
            Assembly Method                   :: Newbler v. 3.0
            Assembly Name                     :: A860_AS2.mpe1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013211575.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 03:37:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,277
            CDSs (total)                      :: 9,181
            Genes (coding)                    :: 9,110
            CDSs (with protein)               :: 9,110
            Genes (RNA)                       :: 96
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 18 of 71
            Pseudo Genes (incomplete)         :: 57 of 71
            Pseudo Genes (internal stop)      :: 2 of 71
            Pseudo Genes (multiple problems)  :: 6 of 71
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:15:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7480166
            Orig. end                         :: 7501204
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP053892.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Peter Leadlay,
            NRRL-B18236 (patent collection, not in online catalogue).
FEATURES             Location/Qualifiers
     region          1..21038
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="19"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21038
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21038
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11038](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11038)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            593..1474
                     /locus_tag="ACTIVE_RS33590"
                     /old_locus_tag="ACTIVE_6735"
     CDS             593..1474
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653490.1"
                     /locus_tag="ACTIVE_RS33590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_6735"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_281382705.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.6e-17,
                     bitscore: 63.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLSVVVLTMGNRPDELARAVRSALEQEHADVEVVLVGNGVDPVG
                     DRAGVPPFDDERVKTISLPTNVGIPAGRNRGVEASCGDVVVFLDDDGFYRSTRLGTYLR
                     DRFAADPGLGVMSFRVRDPEGGRGERRHVPRLRAGDPERSSEVTTFLGGACAIRRAAFD
                     AGGGLPEDFFYAHEETDLAWQILNAGYHIVYDSSAVMFHPAVLPTRHEMFYRYNARNRV
                     WLARRNLPWPLAFTYLAVWIGMTLLRERKPSALKPWFKGFLEGWRKPAGPRRPISYRTA
                     WRMTRMGRPPII"
     gene            complement(1467..2099)
                     /locus_tag="ACTIVE_RS33595"
                     /old_locus_tag="ACTIVE_6736"
     CDS             complement(1467..2099)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF036525.4"
                     /locus_tag="ACTIVE_RS33595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_6736"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_173098760.1"
                     /transl_table=11
                     /translation="MSGRNPAPRRSYGGRSAEERRADRRERLLGAGLELFGTRGYAATS
                     IERLCATASVSTRNFYEEFTGREELLTALHRGINERARAALDTAYAEAAGEPLPVRVER
                     AVRAFVTVTASDPRWARIAFVEVIGVSAGLERHRLQWRAHWEETMLAMIREAVERGEAA
                     DRDYRLTVIAIIGAANNLVHHWSARDQTIPLDDITRELAHLILSAVR"
     misc_feature    complement(2343..2352)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.08"
                     /tool="antismash"
     gene            2556..3107
                     /locus_tag="ACTIVE_RS33600"
                     /old_locus_tag="ACTIVE_6737"
     CDS             2556..3107
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS33600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_6737"
                     /product="hypothetical protein"
                     /protein_id="WP_173098761.1"
                     /transl_table=11
                     /translation="MEPDRTSPATTRRVFLVAGGTAVSAMLVGTAPAGAAEGTAGGDGA
                     ALTTDQTAAVLAVARIGAVYPVPFPAYGESGPAVRRATEARLRAAAAKLDAARLTLVRT
                     AAQDLVARGAHRKSGAALLADLGAGAADTTRRKPLTALTALAVGTVSRHFDPGSDEAAD
                     GWLGMLARLHRNGIRPTVRG"
     gene            3127..4674
                     /locus_tag="ACTIVE_RS33605"
                     /old_locus_tag="ACTIVE_6738"
     CDS             3127..4674
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS33605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_6738"
                     /product="hypothetical protein"
                     /protein_id="WP_173098762.1"
                     /transl_table=11
                     /translation="MTLDAHSPATLERARRELFDRHFDDPNFTGCAIGRRRRAGAVLDE
                     PVVVAMVVKKLGEGFVSRRRLLPKTIGVDGASVGVDVVEVGRLARHGRASGPIPDRLRP
                     PLQGGGISNTHGSVAGSIGCFVRDDTDGTINILSSNHVVGRMSAGSAGETIAQPAAADA
                     GGTAETIAKLKRSVAVSTTATDNLVDAAIAQLDDQSAYAQDVAQGLMAPISADHPVVGM
                     VVAGDAGTNCFLTPIGHVLEKLKVSLLPATSSSPCTAAATIGMHIEKVGRASGYSSSTV
                     DALAAQVKIDFSAKQDRSDVRVLSDLIWTQAFNLPGDSGAIACQGGDGMTFVVRPRVDC
                     PFLGAAGTYYDLPLVDDNPLTSKARDEFFSQSLTGNLLISVLYQNSQVVVDRLQGKTAD
                     PDTQSYAQGYYDQYHDLLAGVLADPDSTVTVTDQNLNDVLNIILGMSGAFGVGEPVLTP
                     DESSAALNLYDAVLSPTLGMNRAQILAYMQRQDVYQQVLDQASTVPTIEVTGPVSAG"
     gene            4720..5970
                     /locus_tag="ACTIVE_RS33610"
                     /old_locus_tag="ACTIVE_6739"
     CDS             4720..5970
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="ACTIVE_RS33610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_6739"
                     /product="S53 family peptidase"
                     /protein_id="WP_173098763.1"
                     /transl_table=11
                     /translation="MTVLPPARVLRTILSVAASLSLAALLPVPPAAADGPPPGAVERAC
                     AWPPQHGRSSCLALRRTDVGVKAGLKGIVGDGYGPSELQDAYNLPSKANGKGQTVAIVD
                     AYDDPNAESDLAAYRSFYGLPPCTTANGCFRKYNQRGETKNYPDPDRDWAGEIALDIDM
                     VSAICPNCHIALVEADSNSNDDLAGAVSTAATTWLTGAKYISNSYGSPESSSSPDRNAD
                     YVAEGIAVTASAGDSGLEVEFPAADPYVVAVGGTSLLPAANARGWDEITWSGTGSGCSK
                     YEQPRPPWQADPGCSHRMVTDVSAVADPETGVAVYDSYGATGGWGVYGGTSASSPIIAS
                     VYALAGPPASDGTDPAYSVYKHADQLNDIVAGRNSWDPCTPSYACQAGPGYDGPTGNGT
                     PDGIGAFVATPGYPWWP"
     gene            6000..6386
                     /locus_tag="ACTIVE_RS33615"
                     /old_locus_tag="ACTIVE_6740"
     CDS             6000..6386
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS33615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_6740"
                     /product="hypothetical protein"
                     /protein_id="WP_173098764.1"
                     /transl_table=11
                     /translation="MPAALALAFAAGCGGGGDGGGRACPMIRGQDGVTVDAAPFAAAHP
                     RARRLCAGKQCVPLAAKPPGPGITVPYHGAPLRIRVVVTAADGSALVDRTVSATAHRVA
                     PKGCGAIARRGRVTVAADGSVRAS"
     gene            complement(6403..7317)
                     /locus_tag="ACTIVE_RS33620"
                     /old_locus_tag="ACTIVE_6741"
     CDS             complement(6403..7317)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543108.1"
                     /locus_tag="ACTIVE_RS33620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_6741"
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="WP_173098765.1"
                     /transl_table=11
                     /translation="MSGPAEPTTGGDRADPATEAFVAHRNLLFTVAYEMLGSAADAEDV
                     LQETWLRWTGVDLAEVRDHRAYLVRITTRQALGRLRTLRRRKESYVGPWLPEPLLTAPD
                     VADDVELADSLSMAMLLVLETLAPTERAVFVLREVFDVPYDEIAEAVGKNPAAVRQIVR
                     RARAHVAARRPRGAVTPDQTRTALREFQRAVETGDLQRLLDVLAPDVVFLGDGGGVAQA
                     ALEPVTGADRVGPIAVGLSRFGAAATLRPAHVNGHPALVFRLDGEIDTVIAVRVDDGLI
                     TGLYAVRNPEKLSRMAEENPVLR"
     gene            7509..7994
                     /locus_tag="ACTIVE_RS33625"
                     /old_locus_tag="ACTIVE_6742"
     CDS             7509..7994
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1298: putative carboxymuconolactone decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009081960.1"
                     /locus_tag="ACTIVE_RS33625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_6742"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_173098766.1"
                     /transl_table=11
                     /translation="MESRFDLMANGVGAKIGKRFFNVSLAIQQSTLPRTVQDLVMMRAS
                     QINGCGYCLDAHAKEAAAAGETAVRLALVAAWRESTVFTEAERAALALAEEGSRLADAH
                     EGVSDATWALVREHYDDDQIAALVYLVAMINAANRLGVIVRSKGGSYEPGVFAGLEN"
     misc_feature    7510..7525
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.91"
                     /tool="antismash"
     misc_feature    complement(7522..7537)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.22"
                     /tool="antismash"
     misc_feature    complement(7528..7543)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.68"
                     /tool="antismash"
     gene            complement(8058..10004)
                     /locus_tag="ACTIVE_RS33630"
                     /old_locus_tag="ACTIVE_6743"
     CDS             complement(8058..10004)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1161: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.4"
                     /locus_tag="ACTIVE_RS33630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_6743"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_173098767.1"
                     /transl_table=11
                     /translation="MTPRSPSPDAEAVVIGGGPAGAAAAALLARRGVATVLVDAGAPVA
                     AHDVLLSGPTLRAVAQLGGTFAATRPVETLELRSAGGHVRTIEGVGGATADRAAFTAFL
                     RDTAAALGATVLTGTAAPVTAAAGGYRTTVGGTEVLARHAIVATGAADAARGPSGGAVH
                     ARRVTGAALGAPASLTLPPPRTADPNEPPTALWALAGAGDTATVLLLRIGADEPDDADL
                     DAHLAADPRFAGASPAGPPVRGPVSVGFSPDAVAAAAGLPVGDAAGLVNPFTGEGLSNA
                     VQSGLLAAEAVAAHRADPDAAGRAYERRLRRSFVGYFETARHASRRHSLTRRVLDAAAE
                     DDHPFFAKARRAVLLPEGLSDLAGADRLGLEGRDAAPMAPFLVACDEVAVATVRAEWPF
                     LARIALAGDVRSRDRLRPAVPFYAALLAGGAPPAAAHATTAAAVELATLGALAFLSTPP
                     ERPPERGIDWALTSTVLAGDFLMAQASRLVADSAPEASRSFADWLAELAELRAEQLAAA
                     TAAEAAALSARVFGALLEYPARIGAQFGGAAPPAVAALREYGHQCGRAFLHAEDVLALR
                     GERTRLDTTRAAMIAARLTAVPEDGDGAVARAASAAREAADAARAALAAVAGSPADRLL
                     RRFLDAVVRPAES"
     gene            complement(10001..11038)
                     /locus_tag="ACTIVE_RS33635"
                     /old_locus_tag="ACTIVE_6744"
     CDS             complement(10001..11038)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891674.1"
                     /locus_tag="ACTIVE_RS33635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_6744"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_173098768.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.7e-49, bitscore:
                     166.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYGRHDEEAALTHTHPPPAGSPAGSPGAPAPEERSRAVERRLLAL
                     CAELSAPLAASARALVERPGKRLRSALVSACARLGPADPERVARFGAVVELLHIASLLH
                     DDIVDRAETRRGGPAAHTVVGSARASLAGLACFALAGQEAADLGRGAATLASRAAAHLS
                     YGEILDVERAFDTAFPIADYRELVERKTGDLFGLCCALGALEAGADADVVRAVERFGRE
                     FGVAFQIADDCLDFAGAPGGSSGGPDKPAGTDHLLGLFGAPTLFALARDTTGELAALLL
                     SPAFSLADMPAVGELVRAYGGLTEASALAAVHRDRAVAALEDVPDPAVRDELLRLTSLA
                     GKDGP"
     gene            complement(11065..13527)
                     /locus_tag="ACTIVE_RS33640"
                     /old_locus_tag="ACTIVE_6745"
     CDS             complement(11065..13527)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012854416.1"
                     /locus_tag="ACTIVE_RS33640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_6745"
                     /product="ATP-binding domain-containing protein"
                     /protein_id="WP_173098769.1"
                     /transl_table=11
                     /translation="MSSQVTGRPTGPGGTVKDREIAAEQRYVDIAYTRLEEMRADAQAM
                     IREGYRQSLAGTKGSLVDRDAMVHQAALRAQALDIADDGLVFGRLDLAGTGEVRYVGRI
                     GVRTSEHDSLVIDWRAPAAEDFYRATPEDPRGVVRRRVLHSRGHTVVDLEDDLLDPDAA
                     DGMTIVGDGAFLASLARAREGAMRDIVATIQREQDEVIRAPADGTVLVRGAPGTGKTAV
                     ALHRVAYLLFRHRRRFGSRGVLVVGPNRRFTAYIERVLPSLGEGSATLRSLGDLVDGVT
                     ATVHDTPALAALKGAEEMATVLRRAVADHAPGAPDELRVVFKGVVLSLDRQRLDRIRGD
                     VHRRSRGSVNAARRQVAEMLLDALWQRFNDLGGPEAAREAEGAEAGLWNAILAADGLGA
                     LDDEQPGRPAGNGTPREQFDARVREQREFADFLVAFWPIRRPAEVLRSLGDPARLRRAA
                     GRDVHRDDVARLAASWAGPAGGEAPFSYQDVALIDEIDALLGAPPRPSRRRASAAADDP
                     FVVDGVNILTGEEVAEDDWEPEMQELTTSMERLERSRRVDDGVVEERPEYAHIVVDEAQ
                     DLSPMQWRMLGRRGRQASWTVVEDPAQSAWEDLAAARTAMDAALSGERPSSRGRNRRRK
                     PAPRRTRHEYELTTNYRNSTEIAAVSARVLARALPEARPARAVRSSGIAPVLRVLPEPD
                     LAAAAREAAEELLAQVEGTIGVIVPFHPAEAHDEGTIPLPHEIASARWDAAARERLAAG
                     LPDRVQVLDVLEAKGLEFDAAVIAAPETVAAQSPNGLRVLYVAVSRATQHLVVLTSAPE
                     WEDILLSG"
     gene            complement(13597..14277)
                     /locus_tag="ACTIVE_RS33645"
                     /old_locus_tag="ACTIVE_6746"
     CDS             complement(13597..14277)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012334.4"
                     /locus_tag="ACTIVE_RS33645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_6746"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_173098770.1"
                     /transl_table=11
                     /translation="MRRTALVAGAAHGVGALAARRLAAAAWDVVAVDTDEDGLAATALR
                     SPNTHVRTCDITEAKDVADILGVTGAVHRLVIAPPPPATPEPPVDEVMRDAFLGPANLV
                     RAALPGMLERAAGEVIVIVPAGTSPASAAAAAAARAYVEALADEHRGRGVAFRCASPPA
                     GVPARLVVDELERSLARPGEVHVAPGPPTGPLPGPLRRVLFGPGTAGRPRRAERAALNV
                     RGSA"
     gene            complement(14274..15020)
                     /locus_tag="ACTIVE_RS33650"
                     /old_locus_tag="ACTIVE_6747"
     CDS             complement(14274..15020)
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012854415.1"
                     /locus_tag="ACTIVE_RS33650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_6747"
                     /product="acetoacetate decarboxylase family protein"
                     /protein_id="WP_246342335.1"
                     /transl_table=11
                     /translation="MTSAAQVHPIQGHEVALPVKIRDAAVASAMFAVPAAAAQAVVAYS
                     GLEIAEPWPGRAICSLAFVRYADGDLGPYHEFAVAFLVRPPGTPPPSGRLGRLHGMRGV
                     GAFIHWLPVNQEFTLECGRSIWGFPKELADIPMDLAGRVKRCAVQVGGRTAVEIAVRPG
                     APMPGGAGAPKVDAYSCLDGVTRRTPWTLAPSDVRMRPGGAKVTLGDHPVAEELRALGL
                     DRARALSSTTVGHLSMSFDPAEEVAP"
     misc_feature    14994..15007
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.12"
                     /tool="antismash"
     misc_feature    15039..15055
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.33"
                     /tool="antismash"
     gene            complement(15099..15593)
                     /locus_tag="ACTIVE_RS33655"
                     /old_locus_tag="ACTIVE_6748"
     CDS             complement(15099..15593)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-161). E-value:
                     2.6e-15. Score: 49.0. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS33655_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653485.1"
                     /locus_tag="ACTIVE_RS33655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_6748"
                     /product="SRPBCC family protein"
                     /protein_id="WP_173098771.1"
                     /transl_table=11
                     /translation="MEREWVVEESVAIEAGPRAVYAAVADLRRTREWSPEVFATWIRGR
                     AVRPGMKFVGFNRLGWRVWFTTCEVTVAVPGEAFAFRVSSFGIPVALWGYRIEDVGGGD
                     AARTRLTEYWEDLRRGTRGAGLVSLLGKVFTGVPAAERAALNRTGMQATLGRIKAGVER
                     G"
     aSDomain        complement(15111..15581)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS33655_Polyketide_cyc2.1
                     "
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.60E-15"
                     /label="ACTIVE_RS33655_Polyketide_cyc2.1"
                     /locus_tag="ACTIVE_RS33655"
                     /protein_end="161"
                     /protein_start="4"
                     /score="49.0"
                     /tool="antismash"
                     /translation="WVVEESVAIEAGPRAVYAAVADLRRTREWSPEVFATWIRGRAVRP
                     GMKFVGFNRLGWRVWFTTCEVTVAVPGEAFAFRVSSFGIPVALWGYRIEDVGGGDAART
                     RLTEYWEDLRRGTRGAGLVSLLGKVFTGVPAAERAALNRTGMQATLGRIKAGV"
     misc_feature    15613..15628
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 20.96"
                     /tool="antismash"
     gene            complement(15628..16239)
                     /locus_tag="ACTIVE_RS33660"
                     /old_locus_tag="ACTIVE_6749"
     CDS             complement(15628..16239)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019629115.1"
                     /locus_tag="ACTIVE_RS33660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_6749"
                     /product="HD domain-containing protein"
                     /protein_id="WP_173098772.1"
                     /transl_table=11
                     /translation="MEVFTRWRTWDAARADLESSGDAARVDLGALAAAAQAAERWHGDQ
                     LRPTGVPYVEHLLEALEVLVRGAGVTDTAVLSAVLLHDVVEDTPATLADVEAAFGPEVT
                     ELVDWVTKPPAGGAGRQAKRAAKSAYLRRLRDAPPEAVLVKLADRVSNVQRLDRMPPDF
                     QRRYYAETVTYIVPLAEPHPWFAAWYGEWREAFSGLRWTT"
     misc_feature    16293..16311
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.81"
                     /tool="antismash"
     gene            16417..18417
                     /locus_tag="ACTIVE_RS33665"
                     /old_locus_tag="ACTIVE_6750"
     CDS             16417..18417
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024753.4"
                     /locus_tag="ACTIVE_RS33665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_6750"
                     /product="PQQ-binding-like beta-propeller repeat protein"
                     /protein_id="WP_173098773.1"
                     /transl_table=11
                     /translation="MALGLLAGALAVALCAVLVERFVLHAEWWQVRHTVTRQPVAPQID
                     VGPPPGPLAPGWEQTTRIHRESAAGYDGVAFAVARGQVVTASGGGLDVRDARDGAERWS
                     YRRTGWTLLGWTSTRSRLVAYFERDGRRGDRLLVGFDELSGAQLWRREAERPAAVSRAT
                     LRWPAGAGVVLTTDDGRRTLYGVSALTGRRLWRTPLPKGCRLYEGAAQPSDALDPADAR
                     TAAGGPDPGDALAALAAGCSGRDGRLLAVDPGHGRVLWSRTLAKGESPEVRVLDGAVLV
                     ADGTALRAFTAGGDQIARWDGDLVCGDQMCPAVRAGGRLLIVRHKDGKGAGTDRMEAVD
                     VPSGRVEWSRDVPGYAALAQAGGTVYALRPRLSDQLLPAGVDTVDPGDGRASTVPVPFA
                     MDPDLRGARPWLAAAGGLLYTAVAEAAPRPEGAARLVALRGAADGPGPAELGGVPVRDW
                     PDACALLKKADLAAVHADDHRMRSARTSVGGVTLPHPVSCTYETTWNEPPGHGTPGKQP
                     GKQPGKARPSGGADPSKSPSGKPGATGAKAGTSPTPHASGGTRSAKPGKPGEAVPEQAF
                     RGLTVSVRWVAETRAEAERMLDALQEVQSQARERPDIPADRAYELGPTAGMIALLVDRA
                     VVVVDVDQPPGAAARLARSVVERLRARAQGA"
     gene            complement(18449..19684)
                     /locus_tag="ACTIVE_RS33670"
                     /old_locus_tag="ACTIVE_6751"
     CDS             complement(18449..19684)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017618792.1"
                     /locus_tag="ACTIVE_RS33670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_6751"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_173098774.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.8e-15,
                     bitscore: 56.1, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRICVCTVVHHPEDARILHRQIRALLDAGHEVTYIAPFRACNVTP
                     WRDVSPVDVPRATGRRRVAALRAARRALAEHAGYADVILLHDPELVVSLPREALDRTVV
                     WDVHEDTAAALTAKEWVPGPVRPLLRPAVRRLERRGERRLKLLLAEEGYRARFRGDHPV
                     VPNTTYVSDLPPGPPDDRRAVYVGNLSAARGALDMIEMARLLAPDGITVELIGSADPDV
                     RPALRDAQRTGVLRWYGFVPNDRALRIAEGAMAGLALLHDEPNYRHSMPTKVVEYMSRG
                     VPVITTPNPPAVDIVEPAGCGLVVPFGDPAAAADAVRRLRDDPELRNRLGERGYAAARA
                     RFHWPVHAERFVAQLEAWAGRSTAVVPDPALSPEPLAEPLTESLPEPPARPLAGPLPEP
                     MPEPMPEAVPDY"
     misc_feature    complement(19700..19714)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 13.65"
                     /tool="antismash"
     misc_feature    19701..19714
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.09"
                     /tool="antismash"
     misc_feature    19748..19762
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.53"
                     /tool="antismash"
ORIGIN
        1 tggtgtcgct gcccgcgtcc ggcacgggcg cgctctggac ggccctcggc ggcgccctgc
       61 tcatccaggt gtacctgctg ctcgactgcg tcgacggcga ggtcgcccgg tacctgcggc
      121 agacgtcggt cgcgggggtc ttcctcgacc gcatcgggca ctacctgtcg gagatctcgc
      181 tgctcatcgg gctcggcttc gccgcgcagg gcggctggaa gaacggcggc tgggccgagc
      241 tcgggctcgt cgccgcgctc ggcgccgcgc tgatcaaggc ggagaccgac aacgtcgtgg
      301 tggcccgcgc caagtccggg ctgaccgccg acccgtccgg cggcgaccgg gcgctgcggc
      361 cccgctccac cgggatcgcg ctggcccggc aggccgcgtc gatgctgcgc ttccaccgca
      421 tcatcggcgc cgtcgagctg tcgctgctga tcctcgccgc cgccctgatc gacaccctga
      481 ccggtgcgga cacgcccgtc gcgacccggg tgctgacggt cgccgtcgcg ctcgtcgcgg
      541 tcgtccagac cctgctgcac ctggtcagca tcctggcctc ccggagactg aagtgaaact
      601 cagcgtcgtc gtcctcacca tgggcaaccg cccggacgag ctggcccgcg ccgtgcgcag
      661 cgcgctggag caggagcacg cggacgtcga ggtcgtcctc gtcggcaacg gcgtcgaccc
      721 ggtgggcgac cgcgcgggcg tcccgccgtt cgacgacgag cgggtcaaga cgatcagcct
      781 gccgacgaac gtcggcatcc cggccggccg caaccgcggc gtcgaggcgt cctgcggcga
      841 cgtggtggtg ttcctcgacg acgacggctt ctaccgctcc acccgcctcg gcacctacct
      901 gcgggaccgg ttcgccgccg acccggggct cggcgtcatg tcgttccggg tccgcgaccc
      961 ggagggcggg cgcggcgagc gccggcacgt gccgcggctg cgcgcgggcg acccggagcg
     1021 ctcctcggag gtcacgacgt tcctcggcgg cgcctgcgcg atccgccgcg ccgcgttcga
     1081 cgcgggcggc ggcctgccgg aggacttctt ctacgcgcac gaggagaccg acctcgcgtg
     1141 gcagatcctc aacgccggct accacatcgt gtacgactcg tccgcggtga tgttccaccc
     1201 ggcggtgctg ccgacgcggc acgagatgtt ctaccggtac aacgcgcgca accgcgtgtg
     1261 gctggcgcgc cggaacctgc cgtggccgct ggcgttcacc tacctcgcgg tgtggatcgg
     1321 catgacgctg ctgcgcgagc gcaagccgag cgccctgaag ccctggttca agggcttcct
     1381 ggagggctgg cgcaagcccg cgggcccgcg ccggccgatc tcctaccgca ccgcctggcg
     1441 gatgacgcgg atgggccgcc cgccgatcat ctgaccgccg acaggatcag gtgcgccagc
     1501 tcccgggtga tgtcgtccag cgggatcgtc tggtcgcggg cggaccagtg gtggacgagg
     1561 ttgttggcgg ccccgatgat cgcgatgacg gtgaggcggt agtcgcggtc ggcggcctcg
     1621 ccgcgctcga cggcctcccg gatcatcgcg agcatcgtct cctcccagtg cgcccgccac
     1681 tgcagccggt gccgttcgag gccggcgctg accccgatga cctcgacgaa cgcgatgcgc
     1741 gcccagcgcg ggtcgctggc ggtgacggtg acgaacgcgc ggacggcgcg ttcgacgcgg
     1801 acgggcaggg gctcgccggc cgcctcggcg taggcggtgt cgagggcggc gcgggcgcgc
     1861 tcgttgatgc cgcggtgcag ggcggtgagc agttcctcgc gtccggtgaa ctcctcgtag
     1921 aagttgcggg tggacacgct cgcggtggcg cagagccgct cgatggaggt cgccgcgtag
     1981 ccgcgggtcc cgaacagttc gaggccggcg ccgagcagcc gctcccgccg gtcggcgcgg
     2041 cgctcctcgg cggagcggcc gccgtagctg cggcgggggg cggggttccg gccgctcatc
     2101 gatctccgtt ctggcggtgt cggaaggagg cagcgccagc ctaaccgcgg ccgcgccccc
     2161 gcgcctcccg cccgccggga cggcggccgc gcggagcgcc gccgagggcg ctccccgatg
     2221 gccggcctgc cggatccgcg gtatccgtcc cgatgtcgac ggtgactgcc gcgccgccgc
     2281 cggaaacgcg cacatcgcga tgacttttgc gaatggccgc cggtcgaaat tcgctccgct
     2341 gcgcaaaaat cgatgccttt ccacttcgcg ccgatatcgg ggtgcgagtc caggtccggc
     2401 cgcaccgttg acagagctga tcaactgatc ttgaatcggc tttcgatcgc tccctctccc
     2461 ctcgtcgccg gcccgggacg gaccagccgt cccgccatcc ggatctgccc gcctttccgc
     2521 tgacacacgg ccccgtgccg tttccggagg ctgccatgga acccgaccga acgtccccgg
     2581 cgacgacccg ccgcgtcttc ctcgtcgccg gcgggaccgc cgtctccgcc atgctcgtcg
     2641 ggacggcgcc ggccggcgcc gccgagggca cggcgggcgg cgacggcgcc gccctgacca
     2701 ccgaccagac ggcggcggtg ctggccgtcg cccggatcgg cgcggtctat cccgtgccgt
     2761 tcccggccta cggcgagtcc ggtccggccg tccgccgggc caccgaggcc cgcctgcggg
     2821 ccgccgccgc gaaactggac gccgcccggc tcacgctcgt gcggaccgcc gcgcaggacc
     2881 tcgtggcccg cggcgcccac cgcaagagcg gggcggcgct gctcgccgac ctcggcgcgg
     2941 gcgccgccga tacgacccgc aggaaaccgc tgaccgcgct caccgcgctc gcggtcggca
     3001 cggtgtcccg ccatttcgat ccgggctccg acgaagccgc ggacggctgg ctcggaatgc
     3061 tcgcccgcct gcaccgcaac ggaatccggc cgacggtccg cggctgagcc gaacaaaggg
     3121 agacccatga cgttggacgc gcattcgccg gcgactctgg aacgcgccag gcgcgagctc
     3181 ttcgaccgcc atttcgacga cccgaatttc accggctgcg cgatcggccg gcgccgcagg
     3241 gcgggggcgg tgctcgacga gcccgtcgtc gtcgccatgg tggtgaagaa actcggtgag
     3301 ggtttcgtgt cccggcgccg gctgctgccg aagacgatcg gcgtggacgg cgcgtccgtc
     3361 ggcgtcgacg tcgtcgaggt gggacgcctc gcccgccacg gccgggccag cggtcccatc
     3421 cccgaccgcc tccgcccgcc gctccagggc ggagggatct ccaacacgca cggttccgtg
     3481 gcggggtcga tcggctgctt cgtccgcgac gacaccgacg gcacgatcaa catcctgtcc
     3541 tcgaaccacg tcgtggggcg gatgagcgcc gggtcggcgg gggagaccat cgcccagccc
     3601 gccgcggccg acgcgggcgg gacggcggag acgatcgcca agctcaagcg gtccgtcgcg
     3661 gtcagcacga ccgccactga caacctcgtg gacgcggcca tcgcgcagct cgacgaccag
     3721 agcgcctacg cccaggacgt ggcgcagggg ctgatggccc cgatctccgc ggaccatccg
     3781 gtggtcggca tggtcgtggc gggcgacgcg ggtaccaact gcttcctcac cccgatcggg
     3841 cacgtcctgg agaagctgaa ggtcagcctg ctgcccgcga cgtcgtcctc gccctgcacg
     3901 gccgccgcga cgatcgggat gcacatcgag aaggtcgggc gggccagcgg ctactcgtcc
     3961 agcaccgtgg acgccctcgc cgcgcaggtg aagatcgact tctccgcgaa gcaggaccgc
     4021 agcgacgtcc gggtgctgtc cgacctcatc tggacccagg cgttcaacct gccgggcgac
     4081 tcgggggcga tcgcctgcca gggcggcgac gggatgacgt tcgtggtgag gccccgggtc
     4141 gactgcccgt tcctgggcgc ggccggcacc tactacgacc tgcccctcgt cgacgacaac
     4201 ccgctgacga gcaaggcgcg cgacgagttc ttctcgcaga gcctcaccgg gaacctgctg
     4261 atctccgtgc tgtaccagaa ctcgcaggtc gtcgtcgacc ggctgcaggg caagacggcg
     4321 gatccggaca cgcagtccta cgcgcagggc tactacgacc agtaccacga cctcctcgcc
     4381 ggcgtcctcg ccgacccgga ctcgaccgtg acggtcaccg accagaacct caacgacgtc
     4441 ctgaacatca tcctcggcat gagcggggcc ttcggggtgg gcgagccggt cctgaccccg
     4501 gacgagtcca gcgcggccct gaacctctac gacgcggtcc tctccccgac gctcggcatg
     4561 aaccgcgcgc agatcctcgc ctacatgcag cggcaggacg tctaccagca ggtcctcgac
     4621 caggcgtcga ccgttccgac gatcgaggtg accggtcccg tctcggcggg ctgacggcgc
     4681 ctgcacggcg cgccgtcccg actctgagga atccaccaga tgacagtgct cccccctgca
     4741 cgggtcctcc ggacgatcct gtccgtcgcc gcgtcgctca gcctcgcggc actgctcccc
     4801 gtcccgccgg cggcggcgga cggaccgccg ccgggcgccg tcgagcgggc gtgcgcgtgg
     4861 ccgccgcagc acggccgatc gtcctgcctg gcgctcaggc gcaccgatgt cggcgttaag
     4921 gccgggctga aaggcatcgt gggcgacgga tacgggccga gcgagctcca ggacgcctac
     4981 aacctgccgt cgaaggcgaa cggcaagggc cagacggtcg cgatcgtcga cgcctacgac
     5041 gacccgaacg ccgaatccga cctcgccgcc taccggtcct tctacgggct cccgccgtgc
     5101 accaccgcga acggctgctt ccgcaagtac aaccagcgcg gcgagacgaa gaactacccc
     5161 gaccccgacc gcgactgggc cggggagatc gccctcgaca tcgacatggt gtccgcgatc
     5221 tgcccgaact gccacatcgc gctcgtcgag gcggactcca actccaacga cgacctcgcc
     5281 ggcgcggtga gcaccgccgc cacgacgtgg ctgacggggg cgaagtacat ctccaacagc
     5341 tacggctcgc cggagtcgtc gtcatcgccc gaccgcaacg ccgactacgt ggccgagggc
     5401 atcgcggtga cggcgtcggc gggcgacagc ggcctggagg tcgagttccc ggccgccgac
     5461 ccgtacgtgg tcgcggtggg cgggacgtcc ctgctgcccg ccgccaacgc ccgcggctgg
     5521 gacgagatca cctggtccgg gacgggctcg ggctgctcga agtacgagca gccgagaccg
     5581 ccgtggcagg ccgaccccgg ctgctcgcac cggatggtca ccgacgtgtc ggccgtcgcc
     5641 gaccccgaga cgggcgtcgc cgtctacgac agctacggcg ccaccggcgg ctggggcgtc
     5701 tacggcggca ccagcgcgtc gtcgccgatc atcgcgtcgg tgtacgcgct ggccggcccg
     5761 cccgcctcgg acggcaccga cccggcctac tccgtctaca agcacgcgga ccagctcaac
     5821 gacatcgtcg cgggccgcaa ctcgtgggac ccgtgcaccc cgtcctacgc ctgccaggcc
     5881 ggtcccggct acgacgggcc gacggggaac gggacgcccg acggcatcgg cgcgttcgtc
     5941 gccacgcccg ggtacccctg gtggccctga tcgggcatcg gcgggcccgc ggtgcgctgg
     6001 tgccggcggc tctcgccctc gccttcgccg ccggctgcgg cggaggcggg gacggcggcg
     6061 gccgggcgtg cccgatgatc cgcgggcagg acggcgtcac ggtcgacgcg gcgccgttcg
     6121 ccgcggccca cccgcgggcc aggcggctgt gcgcggggaa gcagtgcgtc ccgctcgcgg
     6181 cgaagccgcc cggccccggg atcacggtgc cgtatcacgg cgccccgctg cgaatccggg
     6241 tcgtcgtgac ggccgcggac gggtccgcgc tggtcgaccg gaccgtgtcc gccacggcgc
     6301 accgcgtcgc cccgaagggc tgcggcgcga tcgcccgccg ggggcgcgtc accgtggcgg
     6361 ccgacggctc ggtccgcgcg agctgacccc accgggcggc ggtcagcgca ggacggggtt
     6421 ctcctcggcc atgcgggaga gcttctcggg gttgcggacg gcgtagaggc cggtgatgag
     6481 gccgtcgtcg acgcggaccg cgatgacggt gtcgatctcg ccgtcgagcc ggaacaccag
     6541 cgccggatgg ccgttgacgt gcgcggggcg cagcgtcgcc gccgcgccga accgggacag
     6601 cccgaccgcg atgggcccca cccggtccgc tccggtgacg ggctccagcg cggcctgcgc
     6661 gaccccgccg ccgtcgccga ggaacacgac gtcgggggcg aggacgtcca gcaggcgctg
     6721 gaggtcaccg gtctcgaccg cgcgctggaa ctcgcggagc gcggtccggg tctggtccgg
     6781 ggtgaccgcg ccgcgcgggc ggcgggcggc gacgtgcgcc cgcgcccggc ggacgatctg
     6841 ccggacggcg gcggggttct tcccgacggc ctcggcgatc tcgtcgtagg gcacgtcgaa
     6901 cacctcgcgc agcacgaaca cggcccgctc ggtcggggcg agcgtctcca gtaccagcag
     6961 catcgccatc gagaggctgt cggcgagctc gacgtcgtcg gcgacgtcgg gggcggtgag
     7021 cagcggctcg ggcagccagg ggccgacgta ggactccttg cggcggcgga gggtgcgcag
     7081 ccggccgagc gcctgccggg tggtgatccg gacgaggtag gcgcggtggt cccggacctc
     7141 ggcgaggtcg acgcccgtcc agcgcagcca cgtctcctgg aggacgtcct cggcgtcggc
     7201 ggcggagccg agcatctcgt acgcgacggt gaacagcagg ttgcggtggg cgacgaacgc
     7261 ctcggtggcg gggtcggccc ggtcgcctcc ggtcgtcggt tccgcgggtc cgctcatggc
     7321 cggctcctgt tcgctcgtcg tcaaggctgc catgcgcatg ggatgccgcc cgcggccgtc
     7381 ctgtgacacc cgcggccggt ggcgtacgtc acagggcggc gccgtcacag gatccggggc
     7441 gccggcatct ccatggcatc aggacgccgc gcgacgagga gcgcggcgcc cggcgatgag
     7501 gagaagtcat ggaatcccgg ttcgacctga tggccaacgg cgtcggcgcc aagatcggca
     7561 agcggttctt caacgtcagc ctggcgatcc agcagtcgac gctgccccgg accgtccagg
     7621 acctggtgat gatgcgggcc agccagatca acggctgcgg ctactgcctg gacgcccacg
     7681 ccaaggaggc ggcggccgcg ggggagaccg cggtgcggct cgccctggtc gcggcgtggc
     7741 gcgagtccac cgtgttcacc gaggcggagc gggccgcgct ggcgctcgcc gaggagggct
     7801 cccggctcgc cgacgcccac gagggggtgt cggacgcgac gtgggcgctc gtgcgcgagc
     7861 actacgacga cgaccagatc gccgcgctcg tctacctcgt cgcgatgatc aacgcggcga
     7921 accggctcgg cgtgatcgtc cgcagcaagg gcgggtccta cgagcccggc gtgttcgccg
     7981 gcctggagaa ctgaccggcg ggaccggcgt ccggggccgc tcgcccgctg cggcgggcgg
     8041 cctcgccggg ggcgtcgtca ggactcggcg gggcggacga ccgcgtcgag gaaccggcgc
     8101 agcagccggt ccgccggcga gcccgccacg gcggccaggg ccgcccgcgc ggcgtccgcg
     8161 gcctcgcggg cggccgacgc cgcccgcgcc acggcgccgt cgccgtcctc ggggacggcg
     8221 gtgagccgcg ccgcgatcat cgccgcgcgc gtcgtgtcga gccgggtccg ctccccgcgc
     8281 agcgccagga cgtcctcggc gtgcaggaac gcccgcccgc actggtgccc gtactcgcgc
     8341 agcgcggcga cggcgggcgg ggccgcgccg ccgaactgcg cgccgatccg cgccggatac
     8401 tccagcagcg cgccgaacac gcgggcgctg agcgccgcgg cctccgcggc cgtcgcggcg
     8461 gcgagctgct ccgcccgcag ttcggccagc tcggcgagcc agtcggcgaa cgaccgcgac
     8521 gcctccggcg cggagtccgc gacgagccgg gacgcctgcg ccatcaggaa gtcgcccgcg
     8581 aggacggtcg aggtgagcgc ccagtcgatg ccgcgctcgg gcgggcgctc gggcggcgtg
     8641 ctgaggaagg ccagcgcgcc gagcgttgcc agctccacgg cggcggcggt cgtggcgtgc
     8701 gccgcagcgg gcggcgcgcc gcccgccagc agcgccgcgt agaacgggac ggcgggccgc
     8761 agccggtcgc gggaccggac gtcgccggcc agcgcgatcc gggcgaggaa cggccattcg
     8821 gcgcggaccg tggcgacggc gacctcgtcg cacgccacca ggaacggggc catcggcgcg
     8881 gcgtcccggc cttcgaggcc gaggcggtcc gcgcccgcca ggtccgacag cccctccggc
     8941 agcaggaccg cgcggcgcgc cttggcgaag aacgggtggt cgtcctcggc ggcggcgtcg
     9001 aggacccgcc gcgtcagcga gtgccggcgc gacgcgtgcc gcgccgtctc gaagtagccg
     9061 acgaacgagc gccgcagccg gcgctcgtag gcgcggccgg ccgcgtccgg gtcggcccgg
     9121 tgcgccgcga cggcctccgc ggcgagcagg ccgctctgga cggcgttgct cagcccctct
     9181 ccggtgaacg ggttgaccag cccggccgcg tcgccgacgg ggagcccggc cgccgccgcc
     9241 acggcgtcgg gggagaaccc gacgctgacc ggcccgcgca ccgggggacc ggccggggag
     9301 gcgccggcga accgggggtc ggcggcgagg tgcgcgtcga gatccgcgtc gtccggctcg
     9361 tccgcgccga tgcgcagcag caggacggtg gcggtgtccc cggccccggc cagcgcccac
     9421 agcgcggtgg gcggctcgtt cgggtccgcg gtccggggcg gcgggagcgt cagcgacgcc
     9481 ggggcgccca gcgcggcgcc ggtgacgcgg cgggcgtgga cggcgccgcc ggacggcccg
     9541 cgcgccgcgt ccgccgcgcc ggtggcgacg atcgcgtgcc gggcgaggac ctcggtgccg
     9601 ccgacggtgg tgcggtagcc gccggccgcg gccgtcaccg gcgcggccgt cccggtcagg
     9661 accgtcgcgc cgagggcggc ggcggtgtcg cggaggaagg cggtgaacgc ggcgcggtcg
     9721 gccgtggcgc cgccgacgcc ctcgatcgtg cggacgtggc cgccggcgga gcgcagctcc
     9781 agggtctcca ccgggcgggt cgcggcgaac gtcccgccga gctgcgcgac cgcgcgcagc
     9841 gtcgggccgc tgagcagcac gtcgtgggcc gcgaccgggg cgcccgcgtc gaccaggacg
     9901 gtcgcgacgc cgcgccgggc gagcagcgcc gcggccgccg ccccggcggg gccgcccccg
     9961 atgacgacgg cctcggcgtc cggagacggc gatcgggggg tcacggcccg tccttcccgg
    10021 cgagcgaggt cagccgcagc agttcgtccc gtacggcggg gtcgggcacg tcctccaagg
    10081 ccgcgaccgc acggtcccgg tggacagcgg cgagcgcgga cgcctccgtg aggcccccgt
    10141 acgcgcggac gagctcgccg acggcgggca tgtcggcgag ggagaaggcg ggcgagagca
    10201 gcagcgccgc cagctcgccg gtcgtgtcgc gggcgagggc gaacagcgtc ggggcgccga
    10261 acagcccgag caggtggtcg gtcccggcgg gcttgtccgg gccgccggag gagccgccgg
    10321 gggcgcccgc gaagtccagg cagtcgtccg cgatctggaa ggcgaccccg aactccctgc
    10381 cgaagcgctc caccgcccgg acgacgtccg cgtccgcgcc cgcctccagg gcgcccagcg
    10441 cgcagcacag gccgaacaag tcgccggtct tgcgctcgac cagctcgcgg tagtcggcga
    10501 tggggaacgc ggtgtcgaag gcgcgctcca cgtcgaggat ctcgccgtac gacaggtgcg
    10561 cggcggcgcg gctcgccagc gtcgcggcgc cccggccgag gtcggcggcc tcctgcccgg
    10621 ccagcgcgaa gcacgcgagc ccggccagcg acgcccgcgc gctgccgacc accgtgtggg
    10681 ccgccggccc gccgcgccgc gtctccgcgc ggtccacgat gtcgtcgtgc agcagggacg
    10741 cgatgtgcag cagctccacc accgcgccga accgcgccac gcgctcgggg tcggcggggc
    10801 cgaggcgggc gcaggcggac accagcgccg accggagccg cttgccgggc cgttcgacga
    10861 gcgcccgcgc ggacgcggca agcggcgcgg acagctcggc gcacagcgcg agcagccgcc
    10921 gctcgacggc gcgggaccgc tcctccggcg ccggcgcgcc cggagacccg gccggtgagc
    10981 cggccggcgg ggggtgagtg tgggtcagcg ccgcctcctc gtcgtgccga ccgtacatgc
    11041 ggcggtccgc gccgcgccat gggctcagcc ggacaggagg atgtcctccc actcgggggc
    11101 ggacgtcagc acgaccagat gctgcgtcgc gcgggacacg gccacgtaga ggacgcgcag
    11161 cccgttcggc gactgggcgg cgaccgtctc cggcgccgcg atcacggccg cgtcgaactc
    11221 caggcccttg gcctccagga cgtcgaggac ctggacgcgg tcgggcagcc cggcggcgag
    11281 gcgctcgcgg gccgccgcgt cccaccgcgc ggacgcgatc tcgtgcggca gcgggatcgt
    11341 gccctcgtcg tgcgcctcgg ccggatggaa cgggacgatc acgccgatgg tgccctcgac
    11401 ctgcgcgagc agctcctcgg cggcctcccg cgcggcggcg gcgaggtccg gctcgggcag
    11461 gacgcgcagc accggcgcga tcccggacga gcggacggcc cgcgccggcc gcgcctccgg
    11521 cagcgcgcgg gccagcaccc gcgccgacac ggcggcgatc tcggtggagt tgcggtagtt
    11581 cgtcgtcagc tcgtactcgt gccgggtgcg gcgcggcgcg ggcttgcggc gccggttgcg
    11641 gccccgcgac gacgggcgct ccccgctgag cgccgcgtcc atcgccgtgc gggcggcggc
    11701 gaggtcctcc caggcgctct gcgccgggtc ctccacgacc gtccagctgg cctggcggcc
    11761 ccggcggccg agcatccgcc actgcatggg cgacaggtcc tgcgcctcgt ccaccacgat
    11821 gtgcgcgtac tcgggacgct cctccaccac gccgtcgtcg acgcggcggg accgctcgag
    11881 ccgctccatg gacgtggtga gctcctgcat ctccggctcc cagtcgtcct ccgcgacctc
    11941 ctcgccggtg aggatgttga cgccgtccac gacgaacggg tcgtcggcgg cggcggacgc
    12001 gcggcgccgg gacgggcggg gcggcgcgcc gagcagcgcg tcgatctcgt cgatcagcgc
    12061 gacgtcctgg tagctgaacg gcgcctcgcc gcccgcaggc ccggcccagg acgcggcgag
    12121 ccgcgcgacg tcgtcgcggt gcacgtcgcg gcccgcggcg cggcgcagcc gggccgggtc
    12181 gccgagcgag cggagcacct cggcgggccg gcggatcggc cagaacgcga cgaggaagtc
    12241 ggcgaactcg cgctgctcgc ggacgcgcgc gtcgaactgc tcgcggggcg tgccgttgcc
    12301 cgccgggcgg ccgggctgct cgtcgtcgag ggcgccgagg ccgtcggcgg cgaggatcgc
    12361 gttccacagc ccggcctcgg cgccctcggc ctcccgcgcc gcctcggggc cgccgaggtc
    12421 gttgaaccgc tgccacaggg cgtccagcag catctcggcg acctgccggc gggccgcgtt
    12481 cacgctgccg cggctgcgcc ggtgcacgtc gccgcggatg cggtcgaggc gctgccggtc
    12541 gagggagagc acgacgccct tgaacaccac gcgcagctcg tcgggggcgc cgggggcgtg
    12601 gtcggcgacg gcgcggcgca gcacggtcgc catctcctcc gcgcccttca gcgcggcgag
    12661 cgcgggcgtg tcgtggacgg tcgcggtgac cccgtcgacc aggtcgccga gggagcgcag
    12721 cgtcgccgag ccctcgccga gggacggcag cacccgctcg atgtaggcgg tgaagcggcg
    12781 gttcgggccg accaccagca cgccccggga gccgaaccgg cggcggtgcc ggaacagcag
    12841 gtaggcgacg cggtgcagcg cgaccgccgt cttgccggtg ccgggggcgc cgcggaccag
    12901 cacggtcccg tcggcgggcg cgcggatcac ctcgtcctgc tcgcgctgga tcgtcgcgac
    12961 gatgtcgcgc atcgcgccct cgcgggcgcg ggcgagcgag gcgaggaacg cgccgtcgcc
    13021 gacgatcgtc atgccgtcgg cggcgtcggg gtcgagcagg tcgtcctcga ggtcgacgac
    13081 ggtgtgcccg cgcgagtgca ggacgcggcg gcggacgacg ccgcgcgggt cctcgggggt
    13141 ggcgcggtag aagtcctcgg cggcgggcgc ccgccagtcg atgaccaggg agtcgtgctc
    13201 gctggtgcgc acgccgatcc ggccgacgta gcggacctcg cccgtcccgg cgaggtcgag
    13261 gcggccgaac accagcccgt cgtcggcgat gtcgagggcc tgggcgcgca gggccgcctg
    13321 gtggaccatc gcgtcccggt ccaccaggga gcccttggtg cccgcgagcg actgccggta
    13381 gccctcgcgg atcatcgcct gggcgtccgc gcgcatctcc tccagccgcg tgtaggcgat
    13441 gtcgacgtac cgctgctcgg cggcgatctc acggtccttg accgtgccgc cgggaccggt
    13501 cggccgcccg gtgacctggg acgacatgca ggctgctcct cgcgctcggc tcgccgggga
    13561 cggcccccgg cgccctaagg ggcgaaagag acaagcctat gcgctccccc tgacattgag
    13621 cgcggcgcgt tcagcgcggc gcggacgccc ggccgttccc ggaccgaaca ggacgcggcg
    13681 cagcggcccc ggcagcgggc ccgtcggcgg gccgggcgcc acgtgcacct cgccgggccg
    13741 cgccagcgac cgctcgagct cgtcgacgac gagccgggcg gggacgccgg cgggcgggct
    13801 cgcgcagcgg aacgcgacgc cgcgcccgcg gtgctcgtcc gcgagggcct cgacgtaggc
    13861 gcgggccgcg gcggccgcgg cggcggacgc gggggaggtg ccggccggga cgatgacgat
    13921 cacctcgccg gcggcgcgct ccagcatccc gggcagcgcg gcgcgcacga ggttcgccgg
    13981 gccgaggaac gcgtcgcgca tcacctcgtc cacgggcggt tccggggtcg cggggggcgg
    14041 cggggcgatg accagccggt gcacggcccc ggtcacgccc aggatgtccg cgacgtcctt
    14101 ggcctcggtg atgtcgcagg tgcggacgtg ggtgttgggc gagcggagcg cggtggccgc
    14161 gagcccgtcc tcatcggtgt cgacggcgac gacgtcccac gccgccgcgg cgagccgtcg
    14221 cgccgcgagc gctcctacgc cgtgggccgc gccggcgacc agggccgtcc gcctcacggg
    14281 gccacctcct cggccgggtc gaagctcatc gacaggtgcc cgaccgttgt gctgctcagc
    14341 gcgcgcgccc ggtccaggcc cagtgcgcgg agttcctcgg ccaccgggtg gtctcccagg
    14401 gtcaccttgg cgccgccggg gcgcatccgc acatcggacg gcgcgagcgt ccacggcgtc
    14461 cggcgggtga cgccgtccag gcacgagtag gcgtccacct tgggcgctcc ggcgccgccg
    14521 ggcatcggcg cgccgggccg cacggcgatc tcgacggcgg tgcggccgcc gacctgcacg
    14581 gcgcaccgct tgacgcgtcc ggccaggtcc atcgggatgt cggcgagctc cttggggaag
    14641 ccccagatgc tgcggccgca ctccagggtg aactcctggt tgacggggag ccagtggatg
    14701 aacgcgccca cgccccgcat gccgtgcagc cgcccgagcc ggccggacgg cggcggcgtg
    14761 ccgggcggcc ggaccaggaa cgcgacggcg aactcgtggt acggcccgag gtcgccgtcg
    14821 gcgtagcgga cgaacgcgag cgagcagatc gccctccccg gccacggctc ggcgatctcg
    14881 aggccggagt aggcgacgac ggcctgcgcg gcggcggccg ggacggcgaa catggccgag
    14941 gcgacggcgg cgtcccggat cttgaccgga agcgcgacct cgtgcccctg gatcggatgg
    15001 acttgcgcgg cacttgtcac aacggtaagt agaacaggtt ctcgttttgc tgccaagggc
    15061 ggccccgcgc caccccgcgc cgatggccgg cccccggctc agccgcgctc gacgcccgcc
    15121 ttgatccggc cgagcgtcgc ctgcatgccc gtgcggttga gtgccgcacg ctccgcggcc
    15181 ggcacgccgg tgaacacctt cccgagcagc gagaccagcc cggcgccgcg ggtgccgcgc
    15241 cgcaggtcct cccagtactc ggtgagccgc gtccgggcgg cgtccccgcc gccgacgtcc
    15301 tcgatccggt agccccacag cgccaccggg atgccgaagc tcgacacgcg gaaggcgaac
    15361 gcctcgccgg ggacggcgac cgtcacctcg caggtggtga accacacccg ccatccgagc
    15421 cggttgaacc cgacgaactt catgcccggg cggacggcgc gtccgcggat ccaggtcgcg
    15481 aagacctccg ggctccactc gcgcgtccgc cgcaggtcgg cgaccgccgc gtagaccgcc
    15541 cgcggcccgg cctcgatcgc gacgctctcc tcgacaaccc actcgcgttc catggcccga
    15601 tcatcccact ccatgaccgc ctggtcacta cgtggtccag cgcaggccgg agaacgcctc
    15661 gcgccattcg ccgtaccagg ccgcgaacca cgggtgcggc tcggccagcg ggacgatgta
    15721 ggtgaccgtc tcggcgtagt agcggcgctg gaagtccggc ggcatccggt cgagccgctg
    15781 gacgttgctg acccggtcgg cgagcttcac caggaccgcc tccggcgggg cgtcccgcag
    15841 ccgccgcagg tacgcggact tcgcggcgcg cttcgcctgc cgcccggcgc ctcccgccgg
    15901 cggcttggtg acccagtcga cgagctcggt cacctccggc ccgaacgcgg cctccacgtc
    15961 ggcgagcgtc gccggggtgt cctccaccac atcgtgcagc agcacggcgg acagcaccgc
    16021 cgtatcggtg acgcccgcgc ccctgaccag cacctccagg gcctccagca ggtgctcgac
    16081 gtacgggacg ccggtcggcc gcagctggtc gccgtgccag cgctccgccg cttgcgcggc
    16141 cgccgccagc gcgccgaggt ccacgcgggc ggcgtcgccg gacgactcca ggtccgcgcg
    16201 ggcggcgtcc caggtacgcc agcgggtgaa gacctccacg ttccctccgt ttcgtccggc
    16261 ggtgtcgcgc gggcgggcgc gacaaggcaa ggtgggggtc cacagtatgc ggccagtgga
    16321 acgggaatgc gggcggcgga acagggaggc ggcacgggcg tgggcgggag ccggcggcgg
    16381 ccggacggcc ggccggggcc gggaggcggc gtccgcgtgg ccctcggcct cctcgcgggc
    16441 gccctcgccg tcgcgctgtg cgccgtcctc gtcgagcggt tcgtcctgca cgccgagtgg
    16501 tggcaggtcc ggcacaccgt cacccggcag cccgtcgcgc cgcagatcga cgtcggcccg
    16561 ccgcccgggc cgctcgcacc gggctgggag cagaccaccc ggatccaccg cgagtccgcc
    16621 gccgggtacg acggcgtcgc cttcgccgtg gcgcgcgggc aggtggtgac ggcgtccggc
    16681 ggcggcctgg acgtccggga cgcgcgcgac ggcgccgagc gctggagcta ccgccgcacc
    16741 gggtggacgc tgctcggctg gacgtccacg cggtcccggc tcgtcgccta cttcgagcgg
    16801 gacggccggc gcggcgaccg gctgctcgtc gggttcgacg agctgtcggg cgcgcagctg
    16861 tggcggcgcg aggccgagcg ccccgcggcg gtgtcgcgcg cgaccctgcg ctggcccgcc
    16921 ggcgccgggg tggtgctgac caccgacgac ggccgccgca ccctgtacgg cgtgtccgcg
    16981 ctgaccggca ggcggctgtg gcggacgccg ctgccgaagg gatgccggct ctacgagggc
    17041 gcggcgcagc cgtcggacgc cctcgacccg gcggacgccc gcaccgcggc gggcggcccg
    17101 gaccccggcg acgccctcgc ggcgctggcg gcgggctgct ccgggcggga cggccggctg
    17161 ctcgccgtcg acccgggcca cgggcgggtc ctctggagcc ggacgctcgc gaagggggag
    17221 tcgcccgagg tgcgggtgct ggacggcgcg gtcctggtcg cggacgggac ggcgctgcgc
    17281 gcgttcaccg ccggcggcga ccagatcgcc cgctgggacg gcgacctcgt gtgcggcgac
    17341 cagatgtgcc cggccgtccg cgccggcggg cggctcctca tcgtccgcca caaggacggg
    17401 aagggcgccg gcacggaccg gatggaggcg gtcgacgtcc cgtccggccg ggtggagtgg
    17461 tcgcgcgacg tccccggata cgcggcactg gcgcaggcgg gcggcaccgt ctacgcgctg
    17521 cggccgcgcc tgtcggacca gctcctcccg gcgggcgtcg acaccgtgga cccgggggac
    17581 ggccgggcct cgaccgtccc ggtgccgttc gcgatggacc cggacctccg gggagcgcgg
    17641 ccgtggctgg cggcggcggg cgggctgctg tacacggcgg tcgcggaggc ggcgccgcgt
    17701 ccggagggcg cggcccggct ggtcgcgctg cgcggcgcgg cggacgggcc gggccccgcc
    17761 gagctgggcg gggtgccggt gcgcgactgg ccggacgcct gcgcgctgct caagaaggcc
    17821 gacctggcgg ccgtgcacgc cgacgaccac cgcatgcggt ccgcccggac gagcgtcggg
    17881 ggcgtgacgc tgccgcaccc ggtgtcctgc acgtacgaga cgacctggaa cgagccgccg
    17941 ggccacggca cgccggggaa gcagcccggg aagcagccgg ggaaggcacg gccgtcgggc
    18001 ggagcggatc cgtcgaagag cccgtccggc aagccggggg cgaccggcgc gaaggccggg
    18061 acgtcgccga cgccgcacgc ctcgggcggc accagatcgg ccaagcccgg caagcccggc
    18121 gaggccgtgc cggagcaggc gttccgcggg ctgacggtga gcgtccgctg ggtggcggag
    18181 acgcgggcgg aggcagagcg gatgctcgac gcgctgcagg aggtgcagtc gcaggcgcgg
    18241 gagcgccccg acatcccggc cgaccgcgcc tacgagctcg gccccaccgc ggggatgatc
    18301 gcgctgctcg tcgaccgggc ggtcgtggtc gtggacgtgg accagccgcc cggcgccgcg
    18361 gcccggctcg cccggtccgt cgtcgagcgg ctgcgcgcgc gggcgcaggg cgcctgaccg
    18421 tccggcgccc ggcgtcccgc gccggccgtc agtagtccgg aacggcctcg ggcatcggct
    18481 ccggcatcgg ctcgggcagc ggccccgcga gcggcctggc cggcggttcc ggcagcgact
    18541 cggtgagcgg ctcggcgagc ggctccgggg acagcgccgg gtccggcacg acggcggtgc
    18601 tgcggcccgc ccacgcctcc agttgcgcga cgaaccgctc cgcgtgcacc ggccagtgga
    18661 agcgcgcccg ggcggcggcg tagccgcgct cgcccaggcg gttgcgcagc tccgggtcgt
    18721 cgcgcaggcg ccggacggcg tccgcggcgg cggccgggtc gccgaacggg acgaccagcc
    18781 cgcagcccgc cggttcgacg atgtccaccg cgggcgggtt cggcgtcgtg atcaccggga
    18841 cgccacggga catgtactcc acgaccttcg tcggcatcga atgccggtag ttgggctcgt
    18901 cgtgcagcag cgcgagcccc gccatcgcgc cctcggcgat ccgcagcgcc cggtcgttcg
    18961 ggacgaaccc gtaccagcgc agcaccccgg tgcgctgcgc gtcgcgcagc gcgggccgca
    19021 cgtcggggtc ggcggagccg atcagctcca cggtgatccc gtcgggggcc agcagccgcg
    19081 ccatctcgat catgtcgagc gcgccgcgcg ccgccgacag gttgccgacg tagacggcgc
    19141 ggcggtcgtc cggcgggccg ggcggcaggt cggagacgta ggtggtgttc ggcacgaccg
    19201 ggtggtcgcc gcggaaccgg gcccggtagc cctcctcggc gagcagcagc ttcagccgcc
    19261 gctcgccgcg ccgctccagc cgccggacgg ccggccgcag cagcggccgg accggccccg
    19321 gcacccactc cttcgcggtg agcgccgcgg cggtgtcctc gtggacgtcc cacaccacgg
    19381 tccggtcgag cgcctcgcgc ggcagggaga ccaccagctc ggggtcgtgc agcaggatca
    19441 cgtcggcgta gccggcgtgc tcggcgaggg cccggcgggc cgcgcgcagc gccgcgacgc
    19501 ggcgccgccc ggtggcccga gggacgtcga ccgggctgac gtcccgccac ggggtcacgt
    19561 tgcacgcccg gaagggcgcg atgtaggtga cctcatggcc ggcgtcgagg agcgcgcgta
    19621 tctgccggtg cagaatgcgc gcatcctccg gatggtgcac caccgtgcaa acacagatcc
    19681 gcatttccac tcactccgca aggttccgat aaaagcgcct gctgctcgag tctcggtcgg
    19741 gtatggaaat cgtcaatgaa ttccccttgt ccgcgatatg gacggtcggg ggcgactggt
    19801 gcgctccacc gccggcccgc tagaggagtt cgacggtttc gaggtggacg tcccgggtcc
    19861 ggccgcgggt gtcgaacagc agcggggcgt gccgggtgag ggtctcgctg tcgtaggccg
    19921 cgtggtcggc cagcacgatc gccaggtcgg cctcccgcag cgcggtgggc aggtcgcggt
    19981 cggccggcgg gatcgcggtg ccgtcgacct gccattcggt gacgaacggg tcgtggaagg
    20041 acaggtctgc tccgaggcgt gcgaggcggc gtgcgacggg tcgtgctggg gattcgcgtt
    20101 ggtcggcgat gtcggctttg taggtgacgc cgaggaggag gactttggcg tctttgaggg
    20161 cgcgtccttc gcggttgagg agttgttggg cgcgttcggc gacgtagcgg ggcatgcggt
    20221 cgttgatctc ttgggcgagt tcgacgaagc ggaaggggta gcccagggag cggactttgt
    20281 aggacaggta gttggggtcg atggggatgc agtggccgcc gacgccgggt ccggggcgga
    20341 aggcctggaa gccgaagggt ttggtggcgg cgcagtcgat ggcgtcccag aggtcgatgt
    20401 cgagttcgtt gcagaagacg gccatctcgt tgaccagggc gatgttgacg tggcggtagg
    20461 tgttctccag gagtttggcc atctcggcct cgcgggtgcc tttggcctgg acgacgcggt
    20521 cgacgaactt gccgtagaag gcggcggcgg cggtggcgca ggcggcggtg agcccgccga
    20581 cgatcttggg tgtgttgcgg acgccgtaga cctggttgcc ggggtcgatg cgctcgggtg
    20641 agaacgccag gtggaagtct tcgccggcga cgagtccgga ggtttccagg atggggcgga
    20701 cgacctcgtc ggtggtgccg gggtaggtgg tggactccag taccaccagc gtgccgggtt
    20761 ccaggcgccg ggcgatggtc tcggcggcgc cgcggacggc ggtgaggtcg ggtccgccgt
    20821 cgggtgacag gggtgtgggg acgcagatga cgatggtgcg ggcgccttgc aggacggtgt
    20881 cgtccaggct gggggtgaac ccggccgcca gcatgtcctg cacttcggcg ggtgtgacgt
    20941 cgtcgatgtg cgagtcgccg gtggtgaggc cggtgacgac gcgggcgtcg cggtccaggc
    21001 cgccgacgtg cagtccggcc cggcaggcct cccgtacc
//
