LOCUS       NZ_CP053892            25999 bp    DNA     circular CON 05-MAY-2024
DEFINITION  Actinomadura verrucosospora strain NRRL:B18236 chromosome.
ACCESSION   NZ_CP053892
VERSION     NZ_CP053892.1
KEYWORDS    RefSeq.
SOURCE      Actinomadura verrucosospora
  ORGANISM  Actinomadura verrucosospora
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 10214634)
  AUTHORS   Samborskyy,M.
  TITLE     Actinomadura verrucosospora NRRL-B18236 (PFL_A860) Genome sequencing
            and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10214634)
  AUTHORS   Samborskyy,M., Dickens,S. and Scott,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAY-2020) Biochemistry, DNA Sequencing Facility,
            University of Cambridge, 80 Tennis Court Road, Cambridge,
            Cambridgeshire CB2 1GA, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-DEC-2016
            Assembly Method                   :: Newbler v. 3.0
            Assembly Name                     :: A860_AS2.mpe1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013211575.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 03:37:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,277
            CDSs (total)                      :: 9,181
            Genes (coding)                    :: 9,110
            CDSs (with protein)               :: 9,110
            Genes (RNA)                       :: 96
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 18 of 71
            Pseudo Genes (incomplete)         :: 57 of 71
            Pseudo Genes (internal stop)      :: 2 of 71
            Pseudo Genes (multiple problems)  :: 6 of 71
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:15:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2195322
            Orig. end                         :: 2221321
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP053892.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Peter Leadlay,
            NRRL-B18236 (patent collection, not in online catalogue).
FEATURES             Location/Qualifiers
     region          1..25999
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="7"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..25999
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25999
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15999](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15999)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(127..138)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.48"
                     /tool="antismash"
     tRNA            179..250
                     /anticodon=(pos:2195533..2195535,aa:Gly,seq:gcc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="ACTIVE_RS09190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="ACTIVE_7"
                     /product="tRNA-Gly"
     gene            179..250
                     /locus_tag="ACTIVE_RS09190"
                     /old_locus_tag="ACTIVE_7"
     tRNA            291..361
                     /anticodon=(pos:2195645..2195647,aa:Cys,seq:gca)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="ACTIVE_RS09195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="ACTIVE_8"
                     /product="tRNA-Cys"
     gene            291..361
                     /locus_tag="ACTIVE_RS09195"
                     /old_locus_tag="ACTIVE_8"
     tRNA            397..468
                     /anticodon=(pos:2195751..2195753,aa:Val,seq:gac)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="ACTIVE_RS09200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="ACTIVE_9"
                     /product="tRNA-Val"
     gene            397..468
                     /locus_tag="ACTIVE_RS09200"
                     /old_locus_tag="ACTIVE_9"
     misc_feature    complement(653..669)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.53"
                     /tool="antismash"
     gene            1010..3568
                     /locus_tag="ACTIVE_RS09205"
                     /old_locus_tag="ACTIVE_1842"
     CDS             1010..3568
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893995.1"
                     /locus_tag="ACTIVE_RS09205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1842"
                     /product="glycosyl hydrolase family 18 protein"
                     /protein_id="WP_173094647.1"
                     /transl_table=11
                     /translation="MRRFLAVLVSFLVVAALAVAPARAASRLTATFSISGTTGKYVVAN
                     PGTSDVSGWKLTFELPAGVTVSNPQNATVSQNGTKVTLTPAFYINTVKAGGSTEPYSPT
                     FTLSSAAQPTNCLLNGANCDGSGEPPPTVKAVTAEYSVSGTQAKFVVANNTDTAVDGWT
                     IVFDLPDGVTASGAQNGTISQSGTTVTLSSTYYNSSVGAGKTTEPYSPAFTVSKSGAEP
                     TSCRVNDANCDGSADVPPSAPGGLKSTVKTTKTVSLSWDAAKAGSLPVTAYEVYNGSAL
                     ATTVPGTSATVTGLTPNTEYTFTVKARDRKGNLSAASAPVTVKTNDPGDDTQAPSVPAG
                     LHSTGKDSASVTLAWNASTDNTGIANYDVLLDGKVATTVTGTSATVAGLSPSTEYSFTV
                     RARDLYDNVSAESAAVKVTTDDVVSGYARVGYFVQWGIYGRQYFVKNLDTTGNAARLTH
                     LNYAFANIDPKNLTCLQGVTKGTTSDPEDPSQGDGAGDAEADYGRPFSAAQSVDGVADT
                     GWEKLRGNFNQLKKLKAKYPKLKVLISIGGWTYSKYFSDVAATDASRKKFVSSCIDTYI
                     KGDLPEYESAGGAGAAAGIFDGIDLDWEWPGSDGHPGNHVSGADKQNNTLLIAEFRRQL
                     DALTTQTGKRYELTAFTPADPAKIQAGWDLPQVAKSLDIFNIQGYDFHGSGSDNSWEPN
                     RTGHQANLYTDTNDPYPFHFSVENAVNAYLDAGVNPRKLTIGLAYYGRGWQGVTDGGKG
                     GEWQAAKGAAPGQFQEEAGTRGYGNLISSLPNCTVAHDEQAVATSCFTGDGGQWWSFDD
                     AWSIGKKAAWLKSKHLLGAMIWEMSGDPGVLTKALDDGLG"
     gene            complement(3624..4253)
                     /locus_tag="ACTIVE_RS09210"
                     /old_locus_tag="ACTIVE_1843"
     CDS             complement(3624..4253)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044515.1"
                     /locus_tag="ACTIVE_RS09210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1843"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_216858356.1"
                     /transl_table=11
                     /translation="MDVTWPAVDRLLDDGTGHRPRADARRNVERLVAAAHEAAREAGTE
                     ITAHDVARRAGVGIGTFYRRVGSLEELLKAVLDELIAEINATGDACLAADDPWEGFREF
                     AASYIRRRNELCDISETLGDVLGNSRADLRDRIRRLVERAQDAGAMRADVGWTDVAFLL
                     VSAATGPHTLGLRGGEEQWDRNLHVILDGLRAPGSGGLPGEPPRAP"
     misc_feature    complement(4255..4271)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 18.88"
                     /tool="antismash"
     misc_feature    4352..4369
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.83"
                     /tool="antismash"
     gene            4369..5772
                     /locus_tag="ACTIVE_RS09215"
                     /old_locus_tag="ACTIVE_1844"
     CDS             4369..5772
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="ACTIVE_RS09215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1844"
                     /product="MFS transporter"
                     /protein_id="WP_173094648.1"
                     /transl_table=11
                     /translation="MNAKTLVRRPPAAEPDAKERDRFALAAGSAAAFMVFLGTTIVTLA
                     LPTMLRDLHGGPAAGEWIVNGYTLTLAAGLISAGALADVLGARRVFLAGLAVVAPASAV
                     AAAAGAVPVLIAAQLAMGAGAALLLPSSLTLATSGARNTAGRARAVAVWGATGGVGLAA
                     GPLVGGVLIAAAGWRAVFLVNVLLGAVAATVTLLRVGAVPARPRRIDVGGQLTAGAAIA
                     GLVFGMIEGPHLGWTHPAVAAAGAVFAAGVAAFALAERRAADPLLPLGLFRRAGFSGTS
                     ALGVLFNFTFYGVMFALSLLLQDVKGEPPLVAGLSFLPFTGLIALGNLVTPTLLARFGT
                     TAALLAGELLFGGAIAAILFAGPLPQAWPMLLAMTPAGLGAGIVVAAMTTRLVESVPAA
                     LTGAATAAFNTGRQVGSSAGVAVFGPLLAGAAFATGFRIALGIAVTAVAATVPITLALR
                     HDTASTRPQ"
     gene            5769..6134
                     /locus_tag="ACTIVE_RS09220"
     CDS             5769..6134
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS09220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_173094649.1"
                     /transl_table=11
                     /translation="MTSATAADAACAEQGKLTDEAVAALDSTGVLRALRARRPARWGGG
                     EADLADTVIEIGRASASDTPAAPTVRVPNEHQAPTPHSPQNSPQERRHTDEAMRDRATR
                     GGVAAALVTRSRTRAST"
     misc_feature    complement(6501..6510)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.14"
                     /tool="antismash"
     gene            6692..7504
                     /locus_tag="ACTIVE_RS09225"
                     /old_locus_tag="ACTIVE_1845"
     CDS             6692..7504
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017555715.1"
                     /locus_tag="ACTIVE_RS09225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1845"
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="WP_173094650.1"
                     /transl_table=11
                     /translation="MIGLSSPATSEAAPPRAGAGPAGQSAEALLMEMNRPGMDDARREE
                     LRAALVRMHASMVQRIAHRYAHRGEPVEDLAQVAYVGLVNAINRFDPERGGQFFVYAYP
                     MVLGEVRRYFRDRTWGIRVSRRIQELRPRLQVATQRFLQVHGRSPTPGELAAVLGVTAE
                     EITDALLAWESYRPLSLDRTGGDDPDASPLAERLGTEDAALQHVVDGEALHALLARLPK
                     RERTIVLLRFFGNKTQSQIAQELGISQMHVSRLLSKTLRHLREQMYGP"
     gene            complement(8770..9768)
                     /gene="hpnH"
                     /locus_tag="ACTIVE_RS09230"
                     /old_locus_tag="ACTIVE_1846"
     CDS             complement(8770..9768)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076658.1"
                     /locus_tag="ACTIVE_RS09230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1846"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_246342741.1"
                     /sec_met_domain="PF04055 (E-value: 3.9e-20, bitscore: 72.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 8e-08, bitscore: 31.1,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLRQSVRVASHIMSNKARGKDKFPLIMELEPLFACNLKCAGCGK
                     IQHPADVLKRRMPVEQAIAAVKECGAPMVSIAGGEPLMHPQIGEMVDELVRMKKFVFLC
                     TNALLVPKKLDKFKPSPYFAFTVHIDGLQERHDESVCKEGVFDEAVAAVKLIKERGFRV
                     TTNTTFFNTDTPQTVIDVLNYLNDDLQVDEMMLSPGYAYDKAPDQEHFLGVQETRELFR
                     KAFADGNRKRWRLNHSPLFLDFLEGKADFGCTAWAIPSYSLFGWQRPCYLMSDGYAQTY
                     QELLDDTDWESYGRGRDPRCANCMAHCGYEPTAVFTTLGSLKQSLRALREN"
     misc_feature    complement(9723..9737)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.28"
                     /tool="antismash"
     gene            complement(9774..10004)
                     /locus_tag="ACTIVE_RS09235"
                     /old_locus_tag="ACTIVE_1847"
     CDS             complement(9774..10004)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTIVE_RS09235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ACTIVE_1847"
                     /product="hypothetical protein"
                     /protein_id="WP_173094652.1"
                     /transl_table=11
                     /translation="MTRLAVCAARGTAARLRDADTLAVDICYATTNRQRPVTRVLVVGS
                     SNSRRLGPTDTAEHAVAVETTEFTSPKEVRP"
     gene            complement(10001..11866)
                     /gene="shc"
                     /locus_tag="ACTIVE_RS09240"
                     /old_locus_tag="ACTIVE_1848"
     CDS             complement(10001..11866)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540957.1"
                     /locus_tag="ACTIVE_RS09240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1848"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_173094653.1"
                     /sec_met_domain="T2TS (E-value: 2.1e-147, bitscore: 491.0,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTEAPGLTGAAAAAVEAARDHLLGLQSAEGWWKAELETNVTMD
                     AEDLLLRQFLGIRTGAETAAAARWIRSRQRADGTWANFHGGPPDPSTTIEAYVALRLAG
                     DPPDAPHMRKAAAYALEAGGIEGSRVFTRIWLALFGQWSWDDLPVMPPELMFLPSRVPL
                     NVYSWACWARQTIVPLTVLGSLRPVRSLPFDLPELRAGRRPARKATGWGRAFNTLDRVL
                     HVYEKAPVRPLRTAALRRAAEWIVARQEADGCWGGIQPPWVYSLMALSLLGYDLDHPVM
                     KRGLAGLDRFTIEDEKGRRLEACQSPVWDTVLAMNALSDAGAPAGDPALLRAARWIVDE
                     EIRGPGDWSVRRPDLPPGGWAFEFDNDLYPDTDDTAEAILALRRSGLPEARGPIDRAVR
                     WMSGMASKDGGFAAFDADNTQELCTKLPFCDFGAVIDPPSADVTAHVVEALAKEGHAES
                     PVTKRAVVWLLKAQEADGSWFGRWGANHVYGTGGVVPALIAAGVRPDKPPIRRAVAWLE
                     HHQNPDGGWGEDLRSYDDPAWIGRGTSTPSQTAWALLALLAAGERSPAVEAGVRWLVDH
                     QRPDGTWDEDQFTGTGFPGDFYINYHLYRLVFPISALGRYLGRDR"
     gene            complement(11945..12955)
                     /locus_tag="ACTIVE_RS09245"
                     /old_locus_tag="ACTIVE_1849"
     CDS             complement(11945..12955)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634145.1"
                     /locus_tag="ACTIVE_RS09245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1849"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_173094654.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.8e-59, bitscore:
                     200.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVPGPITDGRALVDEAMRACVDRLDPANRRVIAYHLGWTDADG
                     RPAAAGGKALRPALALLSGRAAGAPPENALPGAVAVEFVHAFSLLHDDIMDGDRTRRHR
                     PAAWTVFGAAAAILAGDALLALSEELLLEQHTRGAHWAAEALTAATQRLISGQALDMGF
                     ETRADVTLDECLTMASDKTGALLACASSIGAMLGEAPAGLVTALTGYGTEMGLAFQLVD
                     DLLGIWGTPETTGKPVLSDLRARKKSLPVVAALTAGTPESARLAELYAAPGDPAETDLR
                     EMAELVEAAGGRAWAEAEADRRVALAAKHVGDVEMDDAVRAEFRDVALFVTARDH"
     gene            complement(12952..14283)
                     /gene="hpnE"
                     /locus_tag="ACTIVE_RS09250"
                     /old_locus_tag="ACTIVE_1850"
     CDS             complement(12952..14283)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634146.1"
                     /locus_tag="ACTIVE_RS09250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1850"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_246342742.1"
                     /sec_met_domain="DAO (E-value: 7.7e-07, bitscore: 28.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPRGNAAVVGGGLAGISAALALLEAGVRTTLYEARPRLGGATHS
                     FDRDGLTVDNGQHVFLKCCTAYRGLLERLDALDFVRVQDRLDIPVLTPDGTAGRLRRAK
                     APGPLHLLPALARYRLMPPGDRLRAVRASLALQGIDPQDPALDGQAMGAWLAAHGQRER
                     ARTALWELFLISALNIGVDDAAMGPAAMVCKQGLLGRSDAADIGVPTVPLGELHGVLAA
                     KRIERLGGRVHLKAKVSAVEAGPKLVVDGEPVAADAVVVAVPHRAAAPLVPAQACPDRD
                     RWAGLGASPIINVHVVYDRPVMDVPFAAAVDSPVQWVFDRTDISGLADGQYLAVSVSAA
                     DGWIDTPAADVRAAFLPALERLFPAARRARVTDFFVTRERHATFRQSPGSGALRPASAT
                     RLPGLFLAGAWTDTGWPDTMEGAVRSGLTAARLVRRHLDGVSGR"
     gene            complement(14280..15140)
                     /gene="hpnD"
                     /locus_tag="ACTIVE_RS09255"
                     /old_locus_tag="ACTIVE_1851"
     CDS             complement(14280..15140)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634147.1"
                     /locus_tag="ACTIVE_RS09255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1851"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_173094656.1"
                     /sec_met_domain="phytoene_synt (E-value: 1e-54, bitscore:
                     184.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.9e-65,
                     bitscore: 220.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAAGAYRHCEEVVRSQARNFSYGIRLLPPPKRRALSAVYAFARR
                     VDDIGDDIDAPPDARLAALAAERDRLAGLDAHPDDPVMVALADAARRMPVPLEAFGELI
                     DGCEADVRGAAYDTFDDLLWYCRCVAGSIGRLSLGVFGTRDLRVARARADALGVALQLT
                     NILRDVREDRLGGRVYLPAKDLARFGCTLDQDASGRFTDPPEQLAALVRFQAARAGEWY
                     GTGLRLLPMLDRRSAACTGTMAGIYRRLLRRITADPASALASRMSLPAWEKAAVAATAL
                     TGIRR"
     misc_feature    complement(14463..14465)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15142..15999)
                     /gene="hpnC"
                     /locus_tag="ACTIVE_RS09260"
                     /old_locus_tag="ACTIVE_1852"
     CDS             complement(15142..15999)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634148.1"
                     /locus_tag="ACTIVE_RS09260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1852"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_173094657.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.1e-41,
                     bitscore: 140.2, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 7.1e-41, bitscore:
                     139.3, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSISERLWNETRERETRNRLQARENFPVAARLLPARYRAHLLDVY
                     GYARLVDDIGDEAPPAERAGLLDLIDRDLDRIYAGTAPEIPVMRALARTVHERRIPAEP
                     FRKLVLANRRDQVVTRYRTFGELLDYCTLSADPVGHIVLHVFGAATPARLRLSDRICSA
                     LQIIEHCQDVGEDHRDGRVYLPEEDLRRFGCTEDDFRAAATPTRLRGVIAVQAGRAGRL
                     LAEGAPLVRTLPGFARVAVAGYAAGGSAALAALDRRAYDVLAGPPRPRKTRLLAEWSRM
                     LGRR"
     misc_feature    complement(15979..15981)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15993..16007
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 20.61"
                     /tool="antismash"
     gene            16139..18196
                     /locus_tag="ACTIVE_RS09265"
                     /old_locus_tag="ACTIVE_1853"
     CDS             16139..18196
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025736.4"
                     /locus_tag="ACTIVE_RS09265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1853"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_173094658.1"
                     /transl_table=11
                     /translation="MTPETAPSALPGRRPPLARELAFGLSLFALYAVAAAVPIGDRHAA
                     AADHGRRIHDLERTLHIAAERPLNDWLAGHRTVAVAANYEYATVYVASTLWVLAWLYRR
                     HPDRYRVARTSFALINVIGAVCFALWPVAPPRLVPDLGFVDTVLTHGTWGSWGSPVVDH
                     ADRLAAMPSLHVAWALWVSVELARLPVRRSLQAASLLHVFVTLYVIVATANHYVLDAAG
                     AVAVVWFAYVVTDRDSDRRSRPVVPPEDAFFLAVESDRTPQHVGGLIFLDAPDGTPARE
                     DVIAMLRGKLDELPRLGQRLSPASRLRRRRWVEHPLIDWDWHVHEAVLAESGDAGLNAL
                     VGALQSEPLPRDRPMWRMILVRGYAPDRAAVVFLMHHVVADGMGVITHVLRLLTPPDAL
                     PVAGAGPSATRRALGTLVGIAQLATESRQRTRLPASGTGERAFGTFRLPMPAVRGLARR
                     HRVRVTDVVLCALAGGLRRVGPAAGGPEGGRALRVAVPLMTGGPEVPPEGNHTSAVMVD
                     LPYGPMPEIERLRALAAATRRLRSGTRALASAFVMQRAARALPPVLHAAFARAVYGGRT
                     FQAIATNLPGSNTPARLAGAPMSVAHPIVPTGPGAPLAVGALGWNGMLNMGISAEATLV
                     ADMDALCGAMRDVIEELGAAEAPEPQDGPEPPEAAAARSARRGRGPSVPG"
     gene            18267..19472
                     /locus_tag="ACTIVE_RS09270"
                     /old_locus_tag="ACTIVE_1854"
     CDS             18267..19472
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF020037.4"
                     /locus_tag="ACTIVE_RS09270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1854"
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="WP_173094659.1"
                     /transl_table=11
                     /translation="MAEIDLSAVFDAMPVGCAVLTPGLRYVTVNRAYEGLAGLPREQLV
                     GRPFYEVFPGGPDGQGMSEVRASLERVAETGETDIMPLQRYDIEIPGRPGAYEERYWSI
                     RNASLRAPDGTVTALIHRAEEVTSYIRQLRETHPSDASPADRVEAVQAELFARTRELEE
                     VNQRLHRAREEEERANAALHDALQRQQQAVADTSHDLRAPLTGLQTRLQLALTDPESDS
                     DAILHAALHDADRLGDIVADLLELARLEAGPPVLTETVDLARLVEDELAGHDPGVALTA
                     RLEHGLRVRGSALRLARLLGNLVSNAERHAGSRVEVLLGCDDGRAVLQVVDDGPGIPAG
                     EREAVFRRFYRRPDARGSEPEGTGLGLAIARQIADAHQGTLYVADRPSGTCMVLCLPLC
                     AA"
     misc_feature    complement(18268..18282)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            19569..20597
                     /locus_tag="ACTIVE_RS09275"
                     /old_locus_tag="ACTIVE_1855"
     CDS             19569..20597
                     /NRPS_PKS="Domain: PKS_KR (9-173). E-value: 4.8e-14. Score:
                     44.6. Matches aSDomain:
                     nrpspksdomains_ACTIVE_RS09275_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017602555.1"
                     /locus_tag="ACTIVE_RS09275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1855"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_173094660.1"
                     /transl_table=11
                     /translation="MKYGIDRDSVVVITGASGGIGRAAARAFGARGARIALLARGEEGL
                     DGAADDVERAGGRALPISVDVADDDRVEQAAQRVEDELGSIDVWVNVAFSSVFAPFWEI
                     KPAEFKRITEVTYLGYVNGTRAALKRMMPRERGVIVQCGSALAYRGIPLQSGYCGAKHA
                     VQGFHDALRAELLHECPGVKVTMVEMPGVNTPQFSWVLSRLPRRAQPVPPIYQPEIAAD
                     ALLYAAEHPRRREYWVGGSTVGTLVANKFAAGLLDRYLARTAFSSQQTDQKRPRDQAAN
                     LWEPADDAGGHDYGAHGRFDEEAHPHSPQLWAAKHKYLVGAATAGAAATGAAVGAARLL
                     RR"
     aSDomain        19596..20087
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTIVE_RS09275_PKS_KR.1"
                     /evalue="4.80E-14"
                     /label="ACTIVE_RS09275_PKS_KR.1"
                     /locus_tag="ACTIVE_RS09275"
                     /protein_end="173"
                     /protein_start="9"
                     /score="44.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASGGIGRAAARAFGARGARIALLARGEEGLDGAADDVER
                     AGGRALPISVDVADDDRVEQAAQRVEDELGSIDVWVNVAFSSVFAPFWEIKPAEFKRIT
                     EVTYLGYVNGTRAALKRMMPRERGVIVQCGSALAYRGIPLQSGYCGAKHAVQGFHDALR
                     A"
     CDS_motif       19599..19688
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTIVE_RS09275_0001"
                     /evalue="2.50E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ACTIVE_RS09275"
                     /protein_end="40"
                     /protein_start="10"
                     /score="16.9"
                     /tool="antismash"
                     /translation="VVITGASGGIGRAAARAFGARGARIALLAR"
     gene            20637..21002
                     /locus_tag="ACTIVE_RS09280"
                     /old_locus_tag="ACTIVE_1856"
     CDS             20637..21002
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013868.4"
                     /locus_tag="ACTIVE_RS09280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1856"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_173094661.1"
                     /transl_table=11
                     /translation="MGAAGGAPDGGADFGVAEHDGWTVVTVAGELDLGTAGRLDEHLSK
                     AIGAEGRPRVVVDVTRMTFCDSSGLNVLIRASKRIASMHGRFVMVRPTERVRNVLRVTG
                     LERVFDIRDELPPAGRG"
     gene            complement(21034..22377)
                     /locus_tag="ACTIVE_RS09285"
                     /old_locus_tag="ACTIVE_1857"
     CDS             complement(21034..22377)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540310.1"
                     /locus_tag="ACTIVE_RS09285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1857"
                     /product="cytochrome P450"
                     /protein_id="WP_246342743.1"
                     /sec_met_domain="p450 (E-value: 1.5e-18, bitscore: 65.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPDETTTGDETTTPGETTPGGTDGADDRFTRGFQEMRESRPLG
                     TRNEVVTGPVADWATDFSHMEPEWAADPYPIQDDLRERCPIAHTGRFGGGWLPTRYEDV
                     SAIAYDTERFSSRSIVMSNFRPPLESAPVGGVPPISSDPPFHHDARKLLLPAFTKTAVS
                     RLEPATRAFCHSLIDGLEAGDVVDAARDYAQHIPMRVIADMLGFPPEDGPKFREFVENA
                     LEGVNRPPDERIARMEKLFDYLLEQIRDHVDRPRDDLTTYLIDAELYGRRLDPSHVSGT
                     MALLLIAGIDTTWSAIGASLWHLARTPADRERLVAEPGLLPTAMEEFLRAYAPVTMARL
                     VKQDMHWRGADMKAEDWVLLSFPAANRDPGQFDRAGEVVIDREVNRHAAFGLGIHRCVG
                     SHLARMELRVALEVWLERFPRFALDDPSAVTWSAGQVRGPRTLPLRVG"
     gene            complement(22374..22580)
                     /locus_tag="ACTIVE_RS09290"
                     /old_locus_tag="ACTIVE_1858"
     CDS             complement(22374..22580)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540309.1"
                     /locus_tag="ACTIVE_RS09290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1858"
                     /product="ferredoxin"
                     /protein_id="WP_173094662.1"
                     /transl_table=11
                     /translation="MKVRIDPGRCQGHGRCYDLAPALFGEDDEGYGTVLGDGTVPADGE
                     QDARRAAANCPERAITVVKEAEA"
     gene            complement(22577..23215)
                     /locus_tag="ACTIVE_RS09295"
                     /old_locus_tag="ACTIVE_1859"
     CDS             complement(22577..23215)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540308.1"
                     /locus_tag="ACTIVE_RS09295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1859"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_173094663.1"
                     /transl_table=11
                     /translation="MGRIAGVTAAETRERLLRAAADVFAERGYDGTRVADIAAAAGVSN
                     GALYAHFGSKGELLVAALRTHGRQMLAELVAADPGRPVTESLLIIGRWLPKRRDARGHL
                     VVEALVAARRDADVARPMHDYMGERAALLEELVRAAQAGGEMDGALSPDAIAHFCLLLA
                     MGSVLVPPEMHGVGDEEWSSLLTRVVAAFAPARPAAEAAGPEAETGGTR"
     misc_feature    complement(23261..23275)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.29"
                     /tool="antismash"
     misc_feature    23268..23283
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.88"
                     /tool="antismash"
     gene            23351..24820
                     /locus_tag="ACTIVE_RS09300"
                     /old_locus_tag="ACTIVE_1860"
     CDS             23351..24820
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020542112.1"
                     /locus_tag="ACTIVE_RS09300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1860"
                     /product="MFS transporter"
                     /protein_id="WP_173094664.1"
                     /transl_table=11
                     /translation="MTGTTPAVRRPEPAAGRPGDPWWTLSAVSLASVLTGLGGNTLNVA
                     LPSVVRHFHAGPVAANWMLLAFMLANTVLIVVFGRFADMFGRRAMYLSGLGAYTFASLL
                     LGFAPTAWTVVGLRVLQAAGGAMLLANSAAIVTDAFPRERLGRAMGVYTASFSIAQLAG
                     PTLGGYLTDAFGWRWVFWYNVPFGVLCLVWGAVALRPVEAASRERGVDVPGNVLVLAGL
                     GGLLFGLSQVNERGWHSPAVLAGVAVFAVLLPVFLAVERRAARPVVDTALFRDVPFALG
                     LLATFLNATARMGAVVLLALFFQSAQGDDPVTAGLKVLPMSAVAVLASTGAGFLENRVG
                     ARTMTVAATALTTLGLLELLAVIARDVPYAAVAAGLMLLGAGSGTFLPSNATALLSGLP
                     SHRLGIVNAMRLMVQNTGIVVSTALAFSIIAGPVPAALRAHVFAGDLSRVSGQGVQQLV
                     VGYRYALACMAALSALAVLACLGTRRAERAR"
     gene            complement(24833..25837)
                     /locus_tag="ACTIVE_RS09305"
                     /old_locus_tag="ACTIVE_1861"
     CDS             complement(24833..25837)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021509.4"
                     /locus_tag="ACTIVE_RS09305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_1861"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_173094665.1"
                     /transl_table=11
                     /translation="MAPRTNILAARFERAFDAEIRSRFFRGLEFAGPEGDPGWFGPDSA
                     VWYVHSHLPTLVLGLVGAAYIEGLDPSISWMAYDHSRIPERVDGVPTGGIDPEGAAVRL
                     GHSLSFFIGTAYGSTETAERLARTVRAMHHTVKGTRPDGLPYDADDPDWLRWNYATVVW
                     GLATAHERYHRKPLRGADLERYYGEFVRVGEALGGTDLPATKAEVAECLESYLPRLAVT
                     PIKAFGTGPNLRGNGTKPWEPGSPFMDWAARDMLPHWAQKLALYQRPNPVVLRMRRGAL
                     WLALNGLYDATGPLTEFKQAEARVAGGTSAPVAATAPSEPDPVLTREEVEATA"
     misc_feature    25788..25803
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.03"
                     /tool="antismash"
ORIGIN
        1 cgcgatgtcc gaagtaacag caagttccgc catacctcga ccctaggcgc cccacccttc
       61 gaccggcgcc gaagcatccg gcgcgcgcct cgccggaaac ccggtttggg gaacggccgc
      121 gaacacgcta atgttttccc cgtcgccgca aggggccgca aggcaccggg cagcacacgc
      181 ggaagtggct caggggtaga gcatcacctt gccaaggtga gggtcgcggg ttcaaatccc
      241 gtcttccgct ctgaggggcc tttcaggctg tgatccagaa ggtctcttct ggtggagtgg
      301 ccgagaggcg aggcaacggc ctgcaaagcc gtgtacacgg gttcaaatcc cgtctccacc
      361 tcaaccgccg tgtctccccc cggagaccac gtgcaggggc gattagctca gtgggagagc
      421 gctaccttga cacggtagag gtcactggtt caatcccagt atcgcccacg atcgagtagg
      481 gagtggtgta cccgcggaaa gcgcgggccc gccactctct cttcgtgttc gcccgggggg
      541 cgacccccgg acccccgatg tggagggctc cgccccccac gccccccacg tggttgcggt
      601 tggtgggcat ctttctcgtc tgcgtcgctt ctggttttgg ggcttcgccc cttgccccct
      661 tgtggttcag gtcggcactc ccgtaccggt cggtgagtgg tttggggctt cgccccttgc
      721 ccccttgtgg ttgcggttgc tggtctactg cgggtctcgg cggtggttgt caggtgttga
      781 ccggggtggg ggcgttgttc gggctctttg tgccgagatt cttgcggggt ccgactggtt
      841 cggtgcgcta gctggggtgg ttggcgcggg gggccggacg agtgggggtt gtcggtgaag
      901 gtgcaggcgg ttaccttgct cgttaattga taggaaacct tcctatcaat tgccggttcg
      961 ggggcggccg gtcgtcgtag caccaccacc ccggaagcag gtgttcggca tgcgaagatt
     1021 cctcgcggtc ctggtgtcgt tcctggtcgt cgcggcattg gcggtcgctc ccgcgcgggc
     1081 ggcgtcgcgg ttgaccgcca cgttcagcat ctccgggacg accgggaagt acgtggtcgc
     1141 caatcccggg acgtccgatg tgagcggctg gaagctgacg ttcgaactgc cggcgggcgt
     1201 gacggtgagc aacccgcaga acgccaccgt ctcccagaat gggacgaagg tgaccctcac
     1261 gcccgcgttc tacatcaaca ccgtcaaggc gggcgggagc accgagccgt acagcccgac
     1321 gttcaccctg agttcggccg cgcagccgac gaactgcctg ctcaacggcg cgaactgcga
     1381 cgggtccggc gagccgccgc cgacggtcaa ggcggtgact gcagagtact cggtgagcgg
     1441 gacgcaggcg aagttcgtcg tcgcgaacaa caccgacacg gcggtggacg gctggacgat
     1501 cgtgttcgac ctgccggacg gcgtcaccgc gagcggcgcc cagaatggga cgatcagtca
     1561 gagcggcacg accgtcaccc tgtcgtccac ctactacaac tcgtcggtcg gggcggggaa
     1621 gacgacggag ccgtacagtc cggcgttcac cgtcagcaag tccggtgcgg agccgacgag
     1681 ctgccgggtc aacgacgcca actgcgacgg gtccgcggac gtcccgccga gcgcgcccgg
     1741 cgggctgaag tcgacggtga agacgaccaa gaccgtctcg ctgagctggg acgcggcgaa
     1801 ggcggggagc ctgccggtca ccgcctacga ggtgtacaac gggtcggctc tcgcgacgac
     1861 cgtgcccggt accagcgcga ccgtcaccgg gctcacgccg aacaccgagt acacgttcac
     1921 ggtgaaggcc cgcgatcgga aggggaacct gtccgcggcg agcgcgcccg tcaccgtgaa
     1981 gacgaacgac ccgggcgacg acacgcaggc gccgtccgtc ccggcggggc tgcacagcac
     2041 cggtaaggac tcggcgagcg tcacgctggc gtggaacgcc tcgaccgaca acaccggcat
     2101 cgcgaactac gacgtgctgc tggacgggaa ggtcgccacg acggtgaccg ggacgtccgc
     2161 cacggtcgcg gggctatcgc cgtccaccga gtactcgttc accgtccggg ctcgcgacct
     2221 gtacgacaac gtgtcggcgg agagcgcggc ggtgaaggtg acgacggacg atgtggtgag
     2281 cgggtacgcg cgcgtcggct acttcgtcca gtggggcatc tacgggcggc agtacttcgt
     2341 gaagaacctg gacacgacgg gcaacgcggc gcggctgacc cacctcaact acgcgttcgc
     2401 caacatcgac ccgaagaacc tgacgtgcct gcagggcgtc acgaagggca ccacgtccga
     2461 ccccgaggac ccgagccagg gcgacggcgc gggcgacgcc gaggcggact acggccgccc
     2521 gttcagcgcg gcgcagtcgg tggacggcgt ggccgacacg ggctgggaga agctgcgcgg
     2581 caacttcaac cagctgaaga agctgaaggc gaagtacccg aagctgaagg tcctcatctc
     2641 gatcggcggc tggacgtact cgaagtactt ctccgacgtc gccgcgacgg acgcctcgcg
     2701 gaagaagttc gtcagctcct gcatcgacac ctacatcaag ggcgacctgc ccgaatacga
     2761 gagcgcgggc ggtgcgggcg cggccgccgg gatcttcgac ggcatcgacc tcgactggga
     2821 gtggccgggc tcggacgggc accccggcaa ccacgtcagc ggggccgaca agcagaacaa
     2881 cacactgctc atcgccgagt tccgccgcca gctcgacgct ctgaccacgc agaccggcaa
     2941 gcggtacgag ctgaccgcgt tcacgcccgc ggacccggcg aagatccagg ccggctggga
     3001 cctgccccag gtcgccaagt ccctggacat cttcaacatc cagggctacg acttccacgg
     3061 ctccggcagc gacaactcct gggagccgaa ccggaccggc caccaggcca acctgtacac
     3121 cgacaccaac gacccgtacc cgttccactt cagcgtcgag aacgcggtga acgcctacct
     3181 cgacgccggc gtgaacccgc gcaagctgac gatcgggctc gcctactacg gccgcggctg
     3241 gcagggcgtc accgacggcg gcaagggcgg cgaatggcag gcggccaagg gcgcggcgcc
     3301 cggccagttc caggaggagg cggggacgcg cggctacggc aacctgatct ccagcctgcc
     3361 gaactgcacg gtcgcgcacg atgagcaggc cgtcgcgacg tcgtgcttca ccggcgacgg
     3421 cggccagtgg tggtcgttcg acgacgcctg gtcgatcggg aagaaggcgg cctggctgaa
     3481 gagcaagcac ctgctcggcg ccatgatctg ggagatgtcc ggtgatccgg gcgtgctgac
     3541 caaggcgctc gacgacggct tgggctgacc accgactcag ggccggcgcc gtctcccccg
     3601 cgcggtgccg gccctgaccc ctgtcacggc gcccgcgggg gctcgccggg caggccgccg
     3661 gagccggggg cccgcaggcc gtccaggatg acgtgcaggt tgcggtccca ctgctcctcg
     3721 ccgccccgca ggccgagcgt gtgcgggccg gtcgccgccg acaccagcag gaacgccacg
     3781 tcggtccagc cgacgtcggc gcgcatggcg cccgcgtcct gcgcccgctc gaccagccgc
     3841 cggatgcggt cgcgcaggtc ggcgcgggag ttgccgagga cgtcgccgag cgtctcgctg
     3901 atgtcgcaca gctcgttgcg gcggcggatg taggacgcgg cgaactcgcg gaagccctcc
     3961 cacgggtcgt cggcggccag gcacgcgtcg ccggtcgcgt tgatctcggc gatcagctcg
     4021 tccaggacgg ccttcagcag ctcctccagc gagccgacgc ggcggtagaa ggtgccgatc
     4081 ccgacgccgg cgcggcgcgc gacgtcgtgc gcggtgatct ccgtcccggc ctcgcgggcg
     4141 gcctcatggg ccgccgccac caggcgttcc acgttgcggc gggcatcggc gcggggccgg
     4201 tgcccggtcc cgtcgtccag cagccggtcc acggcgggcc aggtcacgtc catgcgccca
     4261 atgtaccagc aagcggacgg ccagcctcca tttaaatgga cgagctccgt ccgcttgtgc
     4321 tagcgtctgc aaccggacgg ccagagtccg cttgttgaag gggtgtgtat gaacgcgaag
     4381 acgctggtca gacggcctcc agccgcagag ccggatgcga aggaaagaga ccggttcgcg
     4441 ctcgcggcgg ggtcggcggc ggcgttcatg gtgttcctcg gcaccacgat cgtgacgctc
     4501 gcgctgccga cgatgctgcg cgacctgcac ggcgggccgg ccgccgggga atggatcgtc
     4561 aacggctaca cgctgacgct ggccgccggg ctgatcagcg cgggagccct cgcggacgtc
     4621 ctcggcgccc gccgggtgtt cctcgcggga ctggccgtcg tcgcgcccgc gtccgccgtc
     4681 gcggccgccg ccggggccgt cccggtgctg atcgccgcgc aactcgccat gggcgcgggc
     4741 gccgcactgc tgctgcccag ctcgctgacc ctcgccacgt ccggggcgcg gaacaccgcc
     4801 gggcgggcgc gcgccgtggc cgtctggggc gcgaccggcg gcgttggcct ggccgccgga
     4861 ccgctggtcg gcggagtgct gatcgccgcg gccgggtggc gcgcggtgtt cctcgtgaac
     4921 gtcctcctcg gtgcggtggc ggctacggtg acgctccttc gggtcggagc ggtcccggcg
     4981 cgtccgcgcc ggatcgacgt cggcggccag ctcaccgcgg gcgccgcgat cgcgggcctg
     5041 gtcttcggca tgatcgaggg cccgcatctg ggctggacgc acccggcggt ggcggccgcg
     5101 ggagccgtct tcgcagcggg ggtcgccgcg ttcgccctcg cggagcgcag ggccgccgat
     5161 ccgctgctgc ccctcggcct cttccggcgc gcgggcttct ccggcacgtc cgcgctcggc
     5221 gtgctgttca acttcacctt ctacggcgtg atgttcgcct tgagcctgct cctgcaggac
     5281 gtgaaaggcg agccaccgct cgtcgccggc ctctccttcc tgcccttcac cggcctcatc
     5341 gcgctgggca acctcgtgac gccgacgctg ctcgcacggt tcggcaccac cgccgcgctg
     5401 ctcgccgggg aactgctgtt cggcggcgcg atcgccgcga tcctgttcgc cgggccgctg
     5461 ccgcaggcat ggccgatgct gctggccatg accccggcgg gcctgggcgc cggcatcgtc
     5521 gtggccgcga tgacgacgcg cctcgtggag tcggtccccg ccgcgctcac cggcgccgcg
     5581 accgccgcgt tcaacaccgg ccgccaggtc ggctcgtcgg cgggcgtcgc ggtgttcggc
     5641 ccgctcctgg ccggcgcggc gttcgccacg ggcttccgga tcgccctcgg catcgccgtc
     5701 accgccgtgg ccgccaccgt gccgatcaca ctcgccctcc gccacgacac cgcctccacc
     5761 cgaccgcaat gacctcggcc accgccgccg acgcggcgtg cgcggagcag ggaaagctca
     5821 ccgacgaggc cgtcgcggcg ctcgactcga cgggcgtgct gcgggcgctg cgggcgcggc
     5881 ggccggcccg ctggggcggc ggcgaggccg acctcgccga cacagtgatc gagatcggcc
     5941 gcgcgtcggc gtccgacacc ccggcagcgc caaccgtccg agtaccgaac gagcaccaag
     6001 caccgacgcc gcacagcccg cagaactcgc cccaagaacg tcggcacacc gacgaagcca
     6061 tgcgggacag agcaacacgg ggtggggtgg cggcagcgct ggttacgaga agccgcacta
     6121 gggcgtcgac gtaacggcga tggcgcatct agcgcaacgg acgcagcgtc ggcgttggag
     6181 agccacgtcg cgcgcgccgc gcagcgcgag ggcggagccc acgcagcggc accgttagcg
     6241 cagcgtgggg caaggccgtc gaggcgtcgg tgtgggcaac tggtgccggt atggcaaggg
     6301 cagcatgagg cgtaggccag gggcggccgg tgccgtacgg cgagagcagc tatgaccgac
     6361 cgcctcgtcc aagccgacga tccatggcag cggcggtggc gtgggcacgg ggcggcgttg
     6421 ccgagaggag ggggacagcc ggtcggcatc catcccgacg gcggccgcgt tctaccccag
     6481 gtccagccgc aggacggaac gaaaaaagca ggtagacgcc ctgctcggcc agctgcccgg
     6541 atccacttga caccgcgcgt cctgccgccc actcggcggt gattcacgaa cagccatgac
     6601 cggcggaaac ccggggaaca agcacggatc tttatatcgt gagacgatgt atcgaggttc
     6661 caggtgagcg cggctccggc atcgacagga ggtgatcggt ctgagctccc cagcgacatc
     6721 ggaggcggcc ccgccgcgtg cgggcgccgg cccggcgggc cagtccgccg aggcgctgct
     6781 gatggagatg aaccgtcccg gcatggacga cgcccgcagg gaggaactgc gcgcggcgct
     6841 cgtccggatg cacgcgtcga tggtgcagcg gatcgcgcac cgctacgccc accggggaga
     6901 accggtggag gatctggcac aggtggccta cgtcggcctc gtcaacgcga tcaacaggtt
     6961 cgaccccgaa cgcggcggcc agttcttcgt ctacgcctac ccgatggtgc tcggggaggt
     7021 ccgccgctac ttccgtgacc ggacctgggg catccgcgtg tcccgccgca tccaggagct
     7081 gcgcccccgg ttgcaggtcg ccacccagcg cttccttcaa gtgcacggcc gctcccccac
     7141 gcccggcgag ctcgcggccg tactcggcgt caccgcggag gagatcaccg acgccctcct
     7201 ggcgtgggag tcctaccggc cgctctccct ggaccgcacc ggcggcgacg accccgacgc
     7261 gagcccgctc gcggagcggc tcgggaccga ggacgccgcg ctccagcatg tcgtcgacgg
     7321 cgaggcgctg cacgccctgc tggcccggct accgaagcgg gagcgcacga tcgtgctgct
     7381 gcgcttcttc ggcaacaaga cccagtcgca gatcgcacaa gagctcggga tatcccagat
     7441 gcacgtctcg cgcctgctca gcaagacact gcgccacctg cgcgaacaga tgtacggccc
     7501 ctgacccccg cccgcatgca cgggtcccga tcaacacccg caccctggga gcttcctgat
     7561 gcgggtctcg acccccgcgc gtaccagggc ggagcgcacc ccatacggac acgcgcccta
     7621 cccgtgatcc gatccctgcc ccgcccccga agcccttcgc gcgcgccatg cacgagcgcg
     7681 cgttgtacgc gaacatgcgt gcatggcgcg aacgggcgct gcacggcgaa cgggcgtgca
     7741 gcacgcgagc gggtgtgctg ggcgtgagcc agcgtggagt tcgcgaacgg acgtgcaccg
     7801 cgcgagcaga ggcgcaccac acgagcagac gcgcaccgcg ctagcagacg cgttggcccg
     7861 agcgggcgcg ctgtgcgcga gcgcggtgtg caccgcgtga gctggcgtgc accgcgctag
     7921 ccgacgcgca ccgcgcgaac gggcgcgcgc accgcgcaag cagacgcaca tggccgtgag
     7981 cggggttgtg ctgggcgcga gcagacatgc accgcgcaac cagacgcaca ccgcgcaagg
     8041 agacgcgatg gcccgagcgg gcgcgctgcg tgcgagcaag cgcgcatcgc gcgagcgggg
     8101 gtgcttggcg cgagcagacg tgcaccacga acggacgtac accacgaacg ggcgtacacc
     8161 gcgcaagcag gcaaccgcgc gaccgggcgt gctgcgcgcg agcaggcgca ggccgcgaac
     8221 gggcgcgcac ctcgcaagca cgtgtgcacc acgcgaccgg gtgtgctgcg cgcgagcagg
     8281 cgcgcaccgc gtgaacgggc gtgcaccgtg cgagcagacg cacaccgcgc aaggagaagg
     8341 gatggcccga gcgggtgcgc tgcgtgcgag caagcgcgcg ccgcgcgagc agggccgcga
     8401 gcggggggac tgggcgcgag cagacgtgca ccacgaacgg gcgtgcaccg cgcaagcagg
     8461 cgcgcaccgc gtgaacgggc gtgctgcgcg cgagcaggcg tcgcaggtcg cgaatgggcg
     8521 cacctcgcaa gcacgcgtgc accacgcgac cgggcgtgct gcgcgcgagc aggcgcaggc
     8581 cgcgaacggg cgcgcatcgc gcaagcacgc gtgcaccacg cgaccgggtg tgctgcgcgc
     8641 gagcaggcgc aggccgcgaa cgggcgtgga ccgtgcgagc agacgcgcag cgcgcgggcg
     8701 ggcgtgtgta tgtgtgctgc gcacgggtgt ggtgtgcggt gggtgggccg tgtgtcctct
     8761 gtcgggtggt tagttttcgc gtagggcgcg tagggattgt tttagggagc cgagggtggt
     8821 gaagaccgcg gtcggctcgt agccgcagtg ggccatgcag ttggcgcagc gcgggtcgcg
     8881 gccgcggccg taggactccc agtcggtgtc gtcgagtagt tcctggtagg tctgcgcgta
     8941 gccgtccgac atcaggtagc aggggcgctg ccagccgaag agggagtagg acgggatcgc
     9001 ccaggcggtg cagccgaagt cggccttgcc ttcgaggaag tcgaggaaga gcggagagtg
     9061 gttcaggcgc cagcgcttgc ggttgccgtc ggcgaacgcc ttgcggaaca gttcgcgggt
     9121 ctcctggacg ccgaggaagt gctcctggtc gggcgccttg tcgtaggcgt agccgggcga
     9181 gagcatcatc tcgtcgacct gcaggtcgtc gttgaggtag ttcaggacgt cgatgacggt
     9241 ctgcggggtg tcggtgttga agaacgtggt gttggtggtg acgcggaagc cgcgctcctt
     9301 gatcagtttc acggcggcga ccgcttcgtc gaagacgcct tccttgcaga cggactcgtc
     9361 gtgcctttcc tggaggccgt cgatgtggac ggtgaaggcg aagtagggcg acggcttgaa
     9421 cttgtcgagc ttcttgggga cgagcagcgc gttcgtgcag aggaagacga acttcttcat
     9481 cctgacgagt tcgtcgacca tctcgccgat ctgcgggtgc atgagcggtt cgccgccggc
     9541 gatcgacacc atcggggcgc cgcattcctt gacggcggcg atggcctgct cgaccggcat
     9601 gcgccgcttc agcacgtcgg cggggtgctg gatcttgccg cagcccgcgc atttgaggtt
     9661 gcaggcgaac agcggctcga gctccatgat gagcgggaac ttgtccttgc cgcgcgcctt
     9721 gttggacatg atgtgcgagg cgacgcggac gctctggcgc agtggcatcg gcattatggt
     9781 cgaacctcct tcggcgaggt gaactcggtg gtctccacgg cgacggcgtg ttcggcggtg
     9841 tcggtgggac cgaggcggcg ggagttggag gacccgacga cgagcacccg ggtcacgggg
     9901 cgctgccggt tggtggtggc gtagcagatg tccacggcga gcgtgtcggc gtcgcgcagg
     9961 cgcgcggcgg tgccgcgcgc cgcgcacacg gcgagccgcg tcaccggtcc cgtcccaggt
    10021 agcggccgag ggcgctgatg gggaacacca gccggtacag gtggtagttg atgtagaagt
    10081 cgccggggaa gccggtgccc gtgaactggt cctcgtccca ggtgccgtcc gggcgctggt
    10141 ggtcgacgag ccagcggacg ccggcctcga cggccgggga gcgttcgccg gcggcgagca
    10201 gcgcgagcag ggcccaggcc gtctgcgacg gggtggacgt gccgcgcccg atccaggccg
    10261 ggtcgtcgta ggagcgcagg tcctcgcccc agccgccgtc ggggttctgg tggtgctcca
    10321 gccaggcgac ggcgcggcgg atcgggggct tgtccgggcg gacgcccgcg gcgatcagcg
    10381 cgggcaccac gccgcccgtg ccgtagacgt ggttggcgcc ccaccggccg aaccaggacc
    10441 cgtccgcctc ctgcgccttc agcagccaca cgacggcgcg cttggtgacg ggcgactccg
    10501 cgtggccctc cttggcgagg gcctcgacga cgtgcgcggt gacgtccgcc gacggcgggt
    10561 cgatgacggc gccgaagtcg cagaacggca gcttggtgca cagctcctgg gtgttgtcgg
    10621 cgtcgaacgc ggcgaacccg ccgtccttgg acgccatccc ggacatccag cggacggccc
    10681 ggtcgatcgg gccgcgggcc tcgggcagcc cggagcggcg cagcgcgagg atcgcctcgg
    10741 cggtgtcgtc ggtgtcgggg tacaggtcgt tgtcgaactc gaacgcccag ccgcccggcg
    10801 gcaggtccgg gcgccgcacc gaccagtccc ccggtccgcg gatctcctcg tccacgatcc
    10861 agcgggcggc gcgcagcagc gccgggtcgc cggcgggcgc gcccgcgtcc gacagcgcgt
    10921 tcatcgcgag gacggtgtcc cagaccggcg actggcacgc ctcgaggcgg cggcccttct
    10981 cgtcctcgat cgtgaaccgg tcgaggccgg cgaggccgcg cttcatcacc ggatggtcga
    11041 ggtcgtagcc gagcaggctg agcgccatca gcgagtacac ccacggcggc tggatgccgc
    11101 cccagcagcc gtccgcctcc tgccgcgcga cgatccactc cgcggcgcgg cgcagcgcgg
    11161 cggtccgcag cggccgcacc ggcgccttct cgtagacgtg caggacgcgg tcgagggtgt
    11221 tgaacgccct cccccagccg gtcgccttcc gggcggggcg ccggcccgcg cgcagctccg
    11281 gcaggtcgaa cggcagcgac cggacggggc gcagcgaccc gaggacggtc agcggcacga
    11341 tcgtctgccg cgcccagcac gcccagctgt agacgttcag cgggacgcgg ctcggcagga
    11401 acatcagctc cggcggcatg accggcaggt cgtcccagga ccactggccg aacagcgcga
    11461 gccagatgcg ggtgaacacg cgactgccct cgatgccgcc ggcctcgagc gcgtaggcgg
    11521 cggccttgcg catgtgcggg gcgtccgggg ggtcgccggc gagccgcagc gcgacgtacg
    11581 cctcaatggt ggtggacggg tcgggcgggc cgccgtggaa gttcgcccac gtcccgtcgg
    11641 cgcgctgccg cgagcggatc cagcgcgccg ccgcggcggt ctcggccccg gtgcggatgc
    11701 cgaggaactg gcgcagcagc aggtcctcgg cgtccatggt gacgttggtc tccagctccg
    11761 ccttccacca gccctcggcc gactgcaggc cgagcaggtg gtcgcgggcc gcctcgacgg
    11821 cggccgcggc cgctccggtg agtccggggg cttccgtcgt ggtcattcgg catcctgctt
    11881 tctgacggtc tccgttttct cgggtgcggg gttcgggtgg tccccgggtg cgggggtccg
    11941 ccggtcagtg gtcccgggcg gtgacgaaca gcgcgacgtc gcggaactcg gcgcggaccg
    12001 cgtcgtccat ctcgacgtcg ccgacgtgct tggcggccag cgcgacgcgg cggtccgcct
    12061 cggcctcggc ccaggcgcgg ccgcccgcgg cctcgaccag ctccgccatc tcccgcaggt
    12121 cggtctcggc ggggtcgccg ggcgcggcgt acagctcggc gaggcgcgcg gactccggcg
    12181 tcccggcggt gagcgcggcg acgaccggca gcgacttctt gcgggcgcgc aggtcggaca
    12241 gcacgggctt gccggtcgtc tccggtgtcc cccagatgcc gagcaggtcg tcgacgagct
    12301 ggaacgccag tcccatctcc gtcccgtacc cggtgagggc ggtgaccagc ccggcgggcg
    12361 cctcgccgag catcgcgccg atggagctgg cgcaggccag cagcgcgccg gtcttgtcgg
    12421 acgccatcgt caggcattcg tcgagcgtga cgtcggcgcg cgtctcgaac cccatgtcga
    12481 gggcctggcc ggagatgagg cgctgggtgg cggcggtcag cgcctccgcg gcccagtgcg
    12541 cgccgcgggt gtgctgctcc agcagcagtt cctccgacag cgccagcagc gcgtcgccgg
    12601 cgaggatcgc ggcggcggcg ccgaacaccg tccaggccgc gggacggtgc cggcgggtcc
    12661 ggtcgccgtc catgatgtcg tcgtgcagca gcgagaacgc gtgcacgaac tccacggcga
    12721 cggcgccggg cagcgcgttc tccggcggtg cgccggccgc gcgccccgac agcagcgcca
    12781 gcgcggggcg cagcgccttg ccgccggccg cggcgggccg gccgtcggcg tcggtccagc
    12841 cgaggtggta ggcgatgacg cgccggttgg ccgggtcgag ccggtccacg caggcgcgca
    12901 tcgcctcgtc gacgagggcg cgcccgtcgg tgatcgggcc ggggacggcg gtcatcggcc
    12961 gctcaccccg tccaggtgcc gccggaccag ccgggcggcg gtcagtccac tgcgcactgc
    13021 cccctccatg gtgtcgggcc agcccgtgtc ggtccacgcg ccggcgagga acagcccggg
    13081 caggcgcgtc gcggacgcgg gacgcagcgc gccgctgccg gggctctggc ggaacgtcgc
    13141 gtgacgctcg cgggtgacga agaagtcggt gacgcgggcc cgccgggcgg ccgggaagag
    13201 ccgttcgagg gcgggcagga acgcggcgcg gacgtcggcg gcgggcgtgt cgatccagcc
    13261 gtcggcggcc gagaccgata ccgcgaggta ctggccgtcg gccaggccgc tgatgtcggt
    13321 gcggtcgaac acccactgca ccggcgagtc gacggcggcg gcgaacggca cgtccatgac
    13381 cggccggtcg tagacgacgt ggacgttgat gatcgggctg gcgccgaggc cggcccagcg
    13441 gtcccggtcc gggcacgcct gcgccgggac gagcggcgcc gcggcgcggt gcggcaccgc
    13501 gacgacgacg gcgtccgcgg cgacgggttc gccgtccacc acgagcttcg gtcccgcctc
    13561 gaccgccgac accttcgcct tcaggtggac ccgcccgccg agccgctcga tccgcttcgc
    13621 cgcgagcacg ccgtgcagct cgccgagcgg gacggtcggg acgccgatgt ctgcggcgtc
    13681 ggagcgtccg agcaggccct gcttgcacac catcgccgcg gggcccatcg cggcgtcgtc
    13741 cacgccgatg ttcagcgccg agatgaggaa cagctcccac agcgcggtgc gggcccgttc
    13801 gcgctggccg tgggcggcga gccaggcgcc catcgcctgc ccgtcgagcg ccgggtcctg
    13861 cgggtcgatg ccctgcaggg ccagcgacgc gcggacggcg cgcagccggt cgcccggcgg
    13921 catcagccgg taccgggcga gcgcgggcag caggtgcagc ggccccggcg ccttcgcccg
    13981 gcgcagcctc ccggccgtcc cgtccggagt gaggacgggg atgtcgaggc ggtcctggac
    14041 gcggacgaag tccagcgcgt ccagccgctc cagcagcccc cggtaggcgg tgcagcactt
    14101 caggaacacg tgctgcccgt tgtcgacggt caggccgtcc cggtcgaacg aatgggtcgc
    14161 gcccccgagc cggggacgcg cctcgtagag ggtggtgcgc acgcccgcct ccagcagggc
    14221 gagcgcggcg ctgatcccgg cgagcccgcc gccgacgacg gcggcgttcc ctcgggggct
    14281 caccgccgga tcccggtgag cgccgtcgcg gcgacggccg ccttctccca tgcgggcagc
    14341 gacatgcggc tcgccagcgc gctcgccggg tcggcggtga tgcgccgcag caggcgccgg
    14401 tagatgccgg ccatcgtccc cgtgcacgcg gcgctgcgcc ggtcgagcat cggcagcagc
    14461 cgtaaccccg tcccgtacca ctcgcccgcg cgcgccgcct ggaaccggac cagcgccgcg
    14521 agctgctccg gcgggtcggt gaaccggccg gacgcgtcct ggtccagggt gcagccgaac
    14581 cgcgcgaggt ccttggccgg caggtagacg cggccgccga ggcggtcctc gcggacgtcc
    14641 cgcaggatgt tcgtgagctg cagcgcgacg ccgagcgcgt cggcacgcgc ccgcgcgacc
    14701 cggaggtcgc gggtgccgaa cacgccgagc gacagccggc cgatcgagcc ggcgacgcac
    14761 cggcagtacc agagcaggtc gtcgaaggtg tcgtaggccg cgccgcggac gtccgcctcg
    14821 cagccgtcga tcagctcgcc gaacgcctcc agcgggaccg gcatccggcg cgccgcgtcc
    14881 gcgagggcga ccatcaccgg gtcgtccggg tgcgcgtcga ggccggccag gcggtcccgc
    14941 tcggcggcga gcgcggcgag cctcgcatcg ggaggcgcgt cgatgtcgtc gccgatgtcg
    15001 tcgacccgcc gcgcgaaggc gtagacggcg ctcagcgcgc ggcgtttcgg cgggggcagg
    15061 aggcggatcc cgtacgagaa gttgcgcgcc tgcgaacgga cgacctcttc gcagtgccgg
    15121 taggcgccgg ctgcgtccat ctcatctcct tcccagcatc cgcgaccact cggccagcag
    15181 ccgcgtcttc ctcgggcgtg gcggacccgc caggacgtcg taggcgcggc ggtccagcgc
    15241 ggcgagcgcg gcggacccgc ccgccgcgta cccggccacg gcgacgcgcg cgaaccccgg
    15301 cagggtccgg acgagcggcg ccccctcggc gagcagtcgt cctgcccttc ccgcctggac
    15361 ggcgatgaca ccgcgcagcc gggtcggggt ggccgcggcg cggaagtcgt cctcggtgca
    15421 gccgaaccgg cgcaggtcct cctccggcag gtagacgcgg ccgtcgcggt ggtcctcgcc
    15481 gacgtcctgg cagtgctcga tgatctgcag cgcggagcag atccggtcgg agaggcggag
    15541 ccgcgccggg gtggcggcgc cgaacacgtg gagcacgatg tggccgacgg ggtcggccga
    15601 gagcgtgcag tagtcgagca gctcgccgaa cgtccggtag cgggtgacga cctggtcgcg
    15661 gcggttggcc agcaccagct tccggaacgg ctcggcgggg atccggcgct cgtggacggt
    15721 gcgggccagc gcgcgcatga cggggatctc gggcgcggtg ccggcgtaga tccggtcgag
    15781 gtcgcggtcg atgaggtcga gcaggccggc gcgctcagcc ggcggcgcct cgtcgccgat
    15841 gtcgtcgacg aggcgggcgt agccgtagac gtcgagcagg tgggcccggt accgggcggg
    15901 caggaggcgg gcggccaccg ggaagttctc ccgggcctgc agccggttcc tggtctcgcg
    15961 ttcgcgggtc tcgttccata agcgctcgct gatggacatc gtttcctttg ggggcggcgc
    16021 gcggggcggg gcggcgctct gccggtcgca acgatcccca ttacccgttg atcgcctggt
    16081 aaacgcgaac cggccatata tatgtgtata ggccaagttt ttgggttact agagatgggt
    16141 gaccccagaa accgccccct ccgcgcttcc gggccgccgc cccccgctcg cgcgcgaact
    16201 cgcgttcggg ctgtcgctgt tcgccctgta cgccgtcgcc gccgccgtcc cgatcggcga
    16261 ccggcacgcc gccgccgccg accacggccg ccggatccac gacctcgagc gcacgctgca
    16321 catcgccgcc gagcggccgc tcaacgactg gctcgccggc caccggaccg tcgccgtcgc
    16381 cgcgaactac gagtacgcca ccgtctacgt ggcgagcacg ctgtgggtcc tggcctggct
    16441 gtaccgcagg catcccgacc ggtaccgcgt cgcgcgcacc tcgttcgcgc tgatcaacgt
    16501 catcggcgcg gtctgcttcg cgctgtggcc ggtcgcgccg ccgcgcctcg tgcccgacct
    16561 cgggttcgtc gacaccgtgc tgacccacgg cacctggggt tcgtggggca gcccggtcgt
    16621 cgaccacgcc gaccggctcg cggccatgcc gtcgctgcac gtcgcgtggg cgctgtgggt
    16681 gagcgtcgaa ctggcccggc tgccggtgcg gcgctcgctg caggcggcga gcctcctgca
    16741 cgtcttcgtg accctctacg tcatcgtggc gaccgcgaac cactacgtgc tggacgcggc
    16801 gggcgcggtc gccgtggtct ggttcgccta cgtcgtgacc gaccgggact ccgatcgccg
    16861 gagccgtccg gtcgtcccgc ccgaggacgc gttcttcctg gccgtcgagt cggaccggac
    16921 gccgcagcac gtcggcgggc tgatcttcct cgacgcgccc gacgggacgc cggcccgcga
    16981 ggacgtgatc gcgatgctgc gcgggaagct ggacgagctg ccccggctcg gccagcggct
    17041 gtcccccgcg tcgcggctgc ggcggcgccg ctgggtcgag cacccgctga tcgactggga
    17101 ctggcacgtg cacgaggcgg tcctcgccga gagcggcgac gcggggctca acgcgctggt
    17161 cggcgcgctg cagagcgagc cgctgccgcg cgaccgacct atgtggcgga tgatcctggt
    17221 gcgcggctac gcccccgacc gggcggcggt ggtcttcctg atgcaccatg tcgtcgccga
    17281 cggcatgggc gtgatcaccc atgtgctgcg gttgctgact cccccggacg cgctgccggt
    17341 cgcgggcgcc ggcccgtcgg cgacgcgccg cgcgctcggc acgctcgtcg ggatcgcgca
    17401 gctggcgacc gagtcgcggc agcggacccg gctgcccgcg agcggcaccg gcgagcgggc
    17461 gttcggcacg ttccggctgc cgatgccggc ggtacgcggc ctcgcccgca ggcaccgcgt
    17521 gcgggtgacg gacgtggtgc tctgcgcgct ggccggcggg ctgcggcggg tcgggccggc
    17581 cgccggcgga cccgagggcg ggcgcgccct gcgggtcgcg gtgccgctga tgacgggcgg
    17641 gccggaggtg ccgcccgagg gcaaccacac ctcggcggtc atggtcgacc tgccgtacgg
    17701 gccgatgccg gagatcgagc ggttgcgcgc gctggccgcg gccaccaggc ggctgcggtc
    17761 cggcacccgg gcgctggcct cggcgttcgt gatgcagcgg gcggcgcggg cgctgccgcc
    17821 ggtgctgcac gccgcgttcg cgcgggccgt gtacggcggc cggacgttcc aggcgatcgc
    17881 cacgaacctc cccggctcga acactccggc gcggctcgcc ggcgccccga tgtccgtggc
    17941 gcacccgatc gtcccgactg ggcccggcgc gccgctcgcg gtcggcgcgc tcggctggaa
    18001 cgggatgctg aacatgggga tcagcgcgga ggcgacgctg gtggccgaca tggacgcgct
    18061 gtgcggcgcc atgcgcgatg tgatcgagga gctcggcgcc gcggaggcgc cggaaccgca
    18121 ggacgggccg gagccgccgg aggcggccgc cgcacgctcc gcgcggcggg gccgcggccc
    18181 gtccgtcccc ggatgagggc ggggtttttg cggcccggat gcctgcgaca ttccggctat
    18241 ttgccctgaa tggatagata gagaagatgg ccgagatcga cctgtcggcg gtcttcgacg
    18301 cgatgccggt cggctgcgcg gtgctcacgc ccggcctgcg gtacgtcacg gtcaaccgcg
    18361 cctacgaagg gctcgccggg ctcccccgcg agcagctggt cgggcggccc ttctacgagg
    18421 tcttcccggg cggccccgac gggcagggca tgtccgaggt gcgggcgtcc ctggagcggg
    18481 tggcggagac cggcgagacc gacatcatgc cgctccagcg ctacgacatc gagatccccg
    18541 gccgtcccgg cgcctacgag gagcggtact ggagcatccg caacgcatcg ctgcgggctc
    18601 cggacggcac ggtcaccgcc ctcatccacc gggcggagga ggtgacctcc tacatccggc
    18661 agctgcgcga gacccacccg tccgacgcgt cgcccgccga ccgggtcgag gcggtgcagg
    18721 ccgagctgtt cgcccggacc cgcgagctgg aggaggtcaa ccagcggctg caccgcgccc
    18781 gcgaagagga ggagcgggcg aacgcggcgc tgcacgacgc cctgcagcgg cagcagcagg
    18841 cggtcgccga cacctcgcac gacctgcggg ccccgctcac cggcctgcag acccgcctgc
    18901 agctcgcgct caccgacccg gagtcggact cggacgcgat cctgcacgcg gcgctgcacg
    18961 acgccgaccg gctcggcgac atcgtcgcgg acctgctgga gctggcccgg ctggaggccg
    19021 gcccgcccgt cctcaccgag accgtggacc tggcccggct cgtcgaggac gagctggccg
    19081 gccacgatcc cggcgtcgcg ctcaccgcgc ggctggagca cgggctgcgg gtgcgcgggt
    19141 cggcgctgcg gctggcgcgg ctgctgggga acctggtgtc caacgccgaa cggcacgcgg
    19201 gcagccgggt ggaggtgctg ctcggctgcg acgacgggcg ggccgtcctg caggtcgtcg
    19261 acgacggccc gggcatcccg gcgggcgagc gggaggcggt cttccgccga ttctaccgcc
    19321 gtcccgacgc ccgcggcagc gaacccgagg ggacgggcct cggactggcg atcgcccgcc
    19381 agatcgccga cgcccaccag ggcaccttgt acgtcgccga ccggccgtcc ggcacctgca
    19441 tggtcctgtg ccttccgctg tgcgccgcgt agggcggcgg agtccggcca ccgcgtccgg
    19501 tcgcgttacg gacgcgtctg tgcgggcact gctgatctgt gctgaccgag ccggttggga
    19561 gggccgcgat gaagtacggg atcgacaggg acagcgtcgt tgtgatcacc ggggccagcg
    19621 gcggcatcgg acgcgccgcc gcgcgggcct tcggtgcccg cggcgcgcgg atcgccctgc
    19681 tcgcccgtgg tgaggagggg ctggacggcg ccgccgacga cgtcgagcgg gccggcgggc
    19741 gggcgctgcc gatcagcgtg gacgtcgccg acgacgaccg ggtggagcag gccgcgcagc
    19801 gcgtcgagga cgagctcggg tcgatcgacg tctgggtgaa cgtggcgttc tcgtcggtgt
    19861 tcgcgccgtt ctgggagatc aagccggcgg agttcaagcg gatcaccgag gtcacctatc
    19921 tcggctacgt caacggcacg cgggcggcgc tcaagcggat gatgccgcgc gagcggggcg
    19981 tcatcgtcca gtgcgggtcg gcgctggcgt accggggcat cccgctgcag agcgggtact
    20041 gcggcgccaa gcacgccgtc caggggttcc acgacgcgct gcgcgccgag ctgctgcacg
    20101 aatgcccggg cgtgaaggtg acgatggtcg agatgcctgg cgtcaacacc ccgcagttca
    20161 gctgggtgct gtcgcggctg ccgcgccgcg cgcagccggt cccgccgatc taccagccgg
    20221 agatcgcggc ggacgccctg ctgtacgcgg cggagcatcc gcgccggcgc gagtactggg
    20281 tgggcggcag cacggtgggc acgctggtcg cgaacaagtt cgccgccggg ctgctggacc
    20341 gctacctggc gcggaccgcg ttctcctcgc agcagaccga ccagaagcgc ccgcgcgacc
    20401 aggccgcgaa cctgtgggag cccgccgacg acgcaggcgg ccacgactac ggcgcgcacg
    20461 ggcggttcga cgaggaggcg catccgcaca gcccgcagct gtgggccgcc aagcacaagt
    20521 acctggtggg cgcggcgacg gcgggggccg ccgccacggg ggccgcggtg ggcgccgcac
    20581 ggctcctgcg ccggtgaccc cccggcgcgc cggggaaccg atcggagggt gagcgcatgg
    20641 gggccgctgg gggcgcgccg gacggcggcg cggatttcgg ggtcgccgag cacgacgggt
    20701 ggacggtcgt gacggtggcc ggagagctgg acctcggcac ggccgggcgg ctcgacgagc
    20761 acctgtcgaa ggcgatcggc gcggaggggc ggccgcgcgt cgtcgtcgac gtgacgcgca
    20821 tgacgttctg cgactcgtcg gggctgaacg tgctgatccg cgcgagcaag cggatcgcct
    20881 cgatgcacgg ccggttcgtg atggtgcgcc ccaccgagcg ggtccgcaac gtgctgcggg
    20941 tcaccggcct ggagcgcgtc ttcgacatcc gcgacgagct gccgccggcc gggcgcggct
    21001 gacccgcgcc cggcctggcc ggccgccggg aggtcagccg acgcgcagcg gcagggtgcg
    21061 gggcccgcgg acctgcccgg cggaccacgt caccgccgac gggtcgtcga gggcgaagcg
    21121 cgggaaccgc tcgagccaga cctcgagggc gacgcgcagc tccatccggg ccaggtgcga
    21181 gccgacgcag cggtggatgc cgagcccgaa cgcggcgtgc cggttgacct cgcggtcgat
    21241 gacgacctcg ccggcgcggt cgaactgccc ggggtcgcgg ttggcggcgg ggaacgacag
    21301 caggacccag tcctcggcct tcatgtcggc gccgcgccag tgcatgtcct gcttcaccag
    21361 ccgcgccatc gtcaccggcg cgtaggcgcg caggaactcc tccatcgccg tcggcagcag
    21421 ccccggctcg gcgaccagcc gctcccggtc cgccggcgtc ctcgccaggt gccacagcga
    21481 cgcgccgatc gcgctccagg tcgtgtcgat gcccgcgatc agcagcagcg ccatcgtccc
    21541 ggagacgtgc gacgggtcga gcctgcggcc gtacagctcg gcgtcgatca ggtaggtcgt
    21601 gaggtcgtcg cgcggccggt cgacgtggtc gcggatctgc tcgagcaggt agtcgaacag
    21661 cttctccatc cgcgcgatgc gctcgtcggg cggccggttg acgccctcca gcgcgttctc
    21721 gacgaactcg cggaacttcg ggccgtcctc cggcgggaag ccgagcatgt cggcgatgac
    21781 gcgcatcggg atgtgctggg cgtagtcgcg ggcggcgtcg acgacgtcgc cggcctccag
    21841 gccgtcgatg agggagtggc agaacgcgcg ggtcgcgggc tccagccggg agacggccgt
    21901 cttggtgaac gccggcagca gcagcttgcg cgcgtcgtgg tggaacggcg ggtcggacga
    21961 gatcggcggc accccgccga ccggcgccga ctccagcggc gggcggaagt tgctcatgac
    22021 gatcgaccgg gacgagaacc gctcggtgtc gtaggcgatc gcgctgacgt cctcgtagcg
    22081 ggtcggcagc cagccgccgc cgaaccggcc ggtgtgcgcg atcgggcagc gttcgcgcag
    22141 gtcgtcctgg atcgggtagg ggtcggccgc ccattcgggc tccatgtgcg agaagtcggt
    22201 cgcccagtcc gcgaccgggc cggtgacgac ctcgttgcgg gtgccgagcg gccggctctc
    22261 gcgcatctcc tggaagccgc gggtgaagcg gtcgtcggcg ccgtccgtcc cgccgggggt
    22321 cgtctcgccg ggggtggtcg tctcgtcgcc ggtggtggtc tcgtcgggag tggtcatgcc
    22381 tccgcctcct tcacgacggt gatcgcgcgc tcggggcagt tggccgccgc gcggcgcgcg
    22441 tcctgctccc cgtccgccgg gacggtgccg tcgccgagga cggtgccgta gccctcgtcg
    22501 tcctcgccga acagggcggg ggccaggtcg tagcagcggc cgtgcccctg gcagcgcccg
    22561 ggatcgatcc gcaccttcat cgcgttcctc ctgtctccgc ttcgggaccg gccgcctccg
    22621 ccgcggggcg ggccggcgcg aaggccgcga cgacgcgggt cagcagcgac gaccactcct
    22681 cgtcgccgac cccgtgcatc tccggaggga ccagcacgct gcccatcgcc agcaggaggc
    22741 agaagtgcgc gatcgcgtcc ggcgacagcg cgccgtccat ctccccgccg gcctgcgcgg
    22801 cgcgcaccag ctcctcgagc agcgcggcgc gctcgcccat gtagtcgtgc atcggccggg
    22861 ccacgtccgc gtcccggcgg gccgccacca gcgcctccac gaccaggtgg ccgcgcgcgt
    22921 cgcggcgctt cggcagccac cggccgatga tcagcagcga ctcggtgacg gggcgcccgg
    22981 ggtcggcggc gacgagctcg gcgagcatct gccggccgtg cgtgcgcagc gccgcgacga
    23041 gcagctcgcc cttggagccg aagtgcgcgt acagcgcgcc gttgctgacg ccggcggcgg
    23101 ccgcgatgtc ggcgacgcgc gtgccgtcgt agccgcgctc ggcgaagacg tccgccgcgg
    23161 cgcgcagcag ccgctcccgc gtctcggcgg ccgtgacgcc cgcgatccgg cccatggacg
    23221 gaattaaaag accgttcatt cagtaccgtc aagggctgga ttctcgaatt gaattctagt
    23281 atcaagatct agaaagagct tcgtgtctcg tcggccggga ggcgcgcatg gtcgatgccg
    23341 gcgcacccgg atgaccggga cgacgcccgc cgtccggcgc ccggagcccg ccgccggacg
    23401 gcccggcgac ccctggtgga cgctgtcggc ggtgagcctg gcaagcgtcc tgaccggcct
    23461 cggcggcaac accctcaacg tcgcgctgcc ctcggtcgtg cggcacttcc acgccggccc
    23521 cgtcgccgcg aactggatgc tgctggcgtt catgctggcc aacaccgtcc tcatcgtggt
    23581 gttcggacgg ttcgccgaca tgttcggccg ccgcgcgatg tacctgtccg gcctcggcgc
    23641 ctacacgttc gcgagcctcc tgctcgggtt cgccccgacc gcttggacgg tcgtcggcct
    23701 gcgcgtcctg caggccgcgg gcggcgcgat gctgctggcc aacagcgccg ccatcgtcac
    23761 cgacgcgttc ccgcgcgagc ggctcggccg cgcgatgggc gtctacaccg cctcgttctc
    23821 catcgcgcag ctcgccgggc ccaccctcgg cggctacctc accgacgcct tcggctggcg
    23881 ctgggtgttc tggtacaacg tgccgttcgg cgtgctgtgc ctggtctggg gcgccgtcgc
    23941 gctgcggccc gtggaggcgg cgtcgcgcga gcggggcgtc gacgtgcccg gcaacgtgct
    24001 cgtcctcgcc gggctcggcg gcctgctgtt cgggctgtcg caggtcaacg agcggggctg
    24061 gcacagcccc gccgtgctgg cgggcgtcgc ggtcttcgcg gtgctgctgc cggtgttcct
    24121 cgccgtggag cggcgcgccg cccgccccgt cgtcgacacc gcgctgttcc gcgacgtccc
    24181 gttcgcgctc gggctgctcg ccacgttcct caacgcgacc gcgcggatgg gcgccgtcgt
    24241 gctgctcgcg ctgttcttcc agtccgcgca gggcgacgac ccggtcacgg ccggactcaa
    24301 ggtgctgccg atgtcggcgg tcgcggtgct ggcgtccacc ggcgccggct tcctggagaa
    24361 ccgcgtcggc gcccgcacca tgacggtggc cgccaccgcg ctcaccacgc tcggcctgct
    24421 cgaactgctg gcggtgatcg cgcgggacgt cccgtacgcg gcggtcgcgg cgggcctgat
    24481 gctgctcggc gccgggtcgg ggacgttcct gccctcgaac gcgacggcgc tgctcagcgg
    24541 cctgccgtcg caccggctcg ggatcgtcaa cgcgatgcgg ctgatggtgc agaacaccgg
    24601 catcgtggtg agcaccgccc tggccttctc gatcatcgcg ggcccggtgc cggcggcgct
    24661 gcgggcgcac gtgttcgccg gggacctgtc gcgggtgtcg gggcagggcg tccagcagct
    24721 cgtcgtcggc taccggtacg cgctggcctg catggcggcg ctgtcggcgc tcgccgtgct
    24781 cgcctgcctc ggcacccgcc gcgcggagcg cgcacgctag gcggcggtcc cgctacgcgg
    24841 tggcctccac ctcttcgcgg gtcaggacgg ggtcgggctc ggacggcgcc gtcgcggcga
    24901 cgggggcgga cgtcccgccg gcgacccggg cctcggcctg cttgaactcc gtcagcggac
    24961 cggtcgcgtc gtacagcccg ttgagcgcga gccacagggc gccgcggcgc atgcgcagca
    25021 ccaccgggtt gggccgctgg tagagggcca gcttctgcgc ccagtggggg agcatgtcgc
    25081 gggccgccca gtccatgaac gggctgccgg gctcccacgg cttggtgccg ttgccgcgca
    25141 ggttcgggcc cgtcccgaac gccttgatcg gcgtgacggc caggcgcggc aggtaggact
    25201 ccaggcactc ggcgacctcc gccttcgtgg cgggcagatc ggtaccgccg agcgcctccc
    25261 ccacccggac gaactcgccg tagtagcgct ccaggtcggc gccgcgcagc ggcttgcggt
    25321 ggtagcgctc gtgcgccgtc gcgaggcccc acacgacggt ggcgtagttc cagcgcagcc
    25381 agtcggggtc gtcggcgtcg tagggcaggc cgtccgggcg ggtgcccttc acggtgtggt
    25441 gcatggcgcg gacggtgcgc gcgagccgct cggcggtctc ggtggagccg taggcggtgc
    25501 cgatgaagaa cgacagcgag tggccgagcc ggacggcggc gccctccggg tcgatgccgc
    25561 cggtcgggac gccgtccacc cgctcgggga tgcgggagtg gtcgtaggcc atccagctga
    25621 tgctggggtc caggccctcg atgtaggcgg cgccgaccag tccgaggacg agggtcggca
    25681 ggtgcgagtg gacgtaccag accgcgctgt ccgggccgaa ccagcccggg tcgccctcgg
    25741 gtccggcgaa ctccaggccc cggaagaacc gggaccggat ctcggcgtcg aaggcccgct
    25801 cgaagcgtgc cgcgaggatg ttcgtcctgg gtgccatccc ggcgctcccg tcaaaatctg
    25861 gatacgaccg tgtccagacc tcagcgtaag tgtttgggta catgcgtgtc cagacttggt
    25921 atcgtggccg ccatggcgaa cgcccggacg gccgcgaaca cccggtgggc cggggtcccc
    25981 gccgcccggc gccgcgacg
//
