LOCUS       NZ_CP053892            12929 bp    DNA     circular CON 05-MAY-2024
DEFINITION  Actinomadura verrucosospora strain NRRL:B18236 chromosome.
ACCESSION   NZ_CP053892
VERSION     NZ_CP053892.1
KEYWORDS    RefSeq.
SOURCE      Actinomadura verrucosospora
  ORGANISM  Actinomadura verrucosospora
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 10214634)
  AUTHORS   Samborskyy,M.
  TITLE     Actinomadura verrucosospora NRRL-B18236 (PFL_A860) Genome sequencing
            and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10214634)
  AUTHORS   Samborskyy,M., Dickens,S. and Scott,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAY-2020) Biochemistry, DNA Sequencing Facility,
            University of Cambridge, 80 Tennis Court Road, Cambridge,
            Cambridgeshire CB2 1GA, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-DEC-2016
            Assembly Method                   :: Newbler v. 3.0
            Assembly Name                     :: A860_AS2.mpe1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013211575.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 03:37:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,277
            CDSs (total)                      :: 9,181
            Genes (coding)                    :: 9,110
            CDSs (with protein)               :: 9,110
            Genes (RNA)                       :: 96
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 18 of 71
            Pseudo Genes (incomplete)         :: 57 of 71
            Pseudo Genes (internal stop)      :: 2 of 71
            Pseudo Genes (multiple problems)  :: 6 of 71
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:15:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 611175
            Orig. end                         :: 624104
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP053892.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Peter Leadlay,
            NRRL-B18236 (patent collection, not in online catalogue).
FEATURES             Location/Qualifiers
     region          1..12929
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="3"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..12929
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12929
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7929](+)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7929
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     gene            complement(923..1822)
                     /locus_tag="ACTIVE_RS02750"
                     /old_locus_tag="ACTIVE_0551"
     CDS             complement(923..1822)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013130666.1"
                     /locus_tag="ACTIVE_RS02750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_0551"
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="WP_173092480.1"
                     /transl_table=11
                     /translation="MSEFVQYLVNGLTIGAFLALIALGYSMIYGVVRLINFAHGDVFMI
                     GAFAGYAVLTTLGVTGGAAWPALLAAVAVGALTTGVVGTGIARAAYVPLLSSPRLALLI
                     SAIGVSLALEEGVKDLTHARFKSYPGVLDGGRIFSGAVRVTYGQLALVLLSVALMAGLW
                     LFVTRTVTGTAMRALAMDRDAARLQGINVERLILVTFFAGSMLAGAAGVMYGLYYVQIS
                     FGMGFLIGLRAFTAAVLGGIGNLPGTMVAGVCIGLVQSFAAGYVSSRWTDVIIFGLLIA
                     VLALRPTGLFGERVVERA"
     gene            complement(1833..3041)
                     /locus_tag="ACTIVE_RS02755"
                     /old_locus_tag="ACTIVE_0552"
     CDS             complement(1833..3041)
                     /GO_function="GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1282:
                     extracellular ligand-binding receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF024825.4"
                     /locus_tag="ACTIVE_RS02755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_0552"
                     /product="branched-chain amino acid ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_173092482.1"
                     /transl_table=11
                     /translation="MTARRRRRGGARSHGLAAAGAGLLLVPLAAGCGSGGSGGSGGSGD
                     VKIGVPAPLSGDSASAGQDILAAARVAADEVNKAGGVKGKKIKIVQADDQCSAQQGAQA
                     AQKLLNSGVVAVAGGYCSGAAVPAIPIYGRRSVPFVMDASTNPSLTDSGKGKVFRTCGR
                     DDNQGLVAAKFMTGPLGAKRIALLHDNTTYAKGLADAAANSVKQSGGQVVYEDALQPGQ
                     SDYSPVLTKIASTKPDVLYFTGYYAEAGLLMKQRKQLGLKFTLMGGDATTDATVLKTAG
                     SAADGYIATTAPLAKDLPAASGFVSAYKAKNGADPGPFSVYEYDAVKVLAKVIGQTGTK
                     GADIIKGLHGVKDFPGITGPITFDAKGDRTDPLYITVHVQNGAFTAFKKLDRSGAWVDA
                     KAS"
     gene            3199..4176
                     /locus_tag="ACTIVE_RS02760"
                     /old_locus_tag="ACTIVE_0553"
     CDS             3199..4176
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014476.4"
                     /locus_tag="ACTIVE_RS02760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_0553"
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="WP_173092484.1"
                     /transl_table=11
                     /translation="MADVLLLSAADVRAVFDLPAAIESQRAAFAALGTGEARLAPRVLL
                     DGPDGAVAFSYVSRLPGTGAVAKFGSVTPGNAARGLPSVAALVTVQDPVDGRPVAIIEG
                     EAVTTLRTSAASAVAADHLAAPGASRLAVIGCGVQGRAHVRAMPRVRPVERVTVACRNP
                     GTCRAAAELAAELELPVEGTGDARTAVAGADLVVTATTSAEPVVLGEWLEPGCTVLSVG
                     SFAPDRCEVDGALLDRAAAVVVDDVDTAARQAGPIVAGLRDGRLSEDRIRPLGPIVAGL
                     APGRAAADDVVFYNSVGLGVQDAAAAAVIVERARAAGAGRIVAL"
     gene            4284..4895
                     /locus_tag="ACTIVE_RS02765"
                     /old_locus_tag="ACTIVE_0554"
     CDS             4284..4895
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017623952.1"
                     /locus_tag="ACTIVE_RS02765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_0554"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_173092486.1"
                     /transl_table=11
                     /translation="MGGPGDSVRDVLAGNLRRARLELGLSLSELSRRSKIGKATLSQLE
                     AGAGNPTIETVFSLSRALEVPISDLLDHQEPSGLTVVRGADVEVLRGEGVDLRPLRGIE
                     SGGAIFEVYDQQVRAGSRQDSLGHVGTEHTIVQAGRLGVRVDDRDVELGPGDYVSFDAR
                     LPHTYTALDGPVRSVLLLQYRSDQRLHAAPAESPHLVETP"
     gene            5001..6161
                     /locus_tag="ACTIVE_RS02770"
                     /old_locus_tag="ACTIVE_0555"
     CDS             5001..6161
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017593031.1"
                     /locus_tag="ACTIVE_RS02770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_0555"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_173092488.1"
                     /sec_met_domain="DAO (E-value: 1.4e-63, bitscore: 214.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRIVVLGAGMVGAACARELALAGFAVTVVDRSGPAAGTTAHGEG
                     NVLVSDKGPGPELELAKLSRELWPAILDGDPNAGAAEWDPKGGIVVATTPEGAGALAEF
                     AEGQRKAGVTAEEMDAAALAAAEPHLTRDVAMAVHYSEDAQVQPAGAATALLAAAVRAG
                     AGLRTGCEVLGAVRRGGRITGVRTSTGTIECDAVVNAAGPWSGEVAKRLGVRLGVRPRR
                     GEVLVTAPMPPTVFHKVYDADYVGAVGSAAEDLQASAVVEATRGGTILLGSSRRRVGFD
                     DRIRPEVLSVIAAKALRLFPMLAGVPVIRAYGGFRPFVPDHLPVIGADPELDGLWHATG
                     HEGAGIGLSAGTAAVLRDLMLGREPAIDAAPFRADRPAVQSEGENL"
     gene            6158..6472
                     /locus_tag="ACTIVE_RS02775"
                     /old_locus_tag="ACTIVE_0556"
     CDS             6158..6472
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017593032.1"
                     /locus_tag="ACTIVE_RS02775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_0556"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_173092490.1"
                     /sec_met_domain="Fer2_4 (E-value: 3.7e-24, bitscore: 83.7,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSARLVPAAGDASGRRPDVPLRITVDGEPVDGVAGQTIAGVLLAS
                     GRRTWRSGPSGAPRGVFCGIGACFDCLVTVNGVRDVRACRRRAHDGDAVATQSRGEDAR
                     "
     gene            6469..7929
                     /locus_tag="ACTIVE_RS48055"
                     /old_locus_tag="ACTIVE_0557"
     CDS             6469..7929
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017593033.1"
                     /locus_tag="ACTIVE_RS48055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_0557"
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="WP_173092492.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.4e-25, bitscore:
                     86.6, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 1.2e-07, bitscore: 30.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 9.2e-09, bitscore:
                     34.6, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRRVVVVGAGPAGLGAAAGALRAGADVTLIDASEQPGGQYHRML
                     PDAFAAAAPGRLHHGWQGFERLRDHVLRHPRCDWWPESTVWSIERHDEGAPAVHVLRGE
                     ADAAGRERRVLRADALVLAPGAHDRVLPFPGWGLPGVYTAGAAQALAKGERLVVGDPVL
                     IAGSGPFLLPVAASLIEAGATVLEVLEANPAATVARGWARRPWELASQAGKAGELAEYA
                     GLLARHRVPYRTGRAVIEARGDGRVEEAVTARLRPDWSVVPGTERTVPVDALCVTHGFS
                     PQLELPVAAGCALARTSGGSFTEVDADQRTTAPGVYAAGEITGIGGAPAARTEGLLAGW
                     IAGGGDPAAREAGALRRRRDQARAFAARLAAAHPIGAAWPGWLRDETVVCRCEETTYGS
                     LCRAAGDEASGSARAVKLGTRAGLGPCQARICGPTVAELLSGKVPGANPHHRPIAQPIR
                     LGELASPPTENTGNTKNRRNPDKKESAR"
     gene            7926..8855
                     /locus_tag="ACTIVE_RS02785"
                     /old_locus_tag="ACTIVE_0558"
     CDS             7926..8855
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017593034.1"
                     /locus_tag="ACTIVE_RS02785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_0558"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_173092494.1"
                     /transl_table=11
                     /translation="MSDTKLLSLGGVIVATALPYYEDASAPAGLAVDYDKYAEHCRWLV
                     DNGCRGVGPNGSLGEYSSLTDDERRRVARTAVEAVGKDGVVVVGVHGPGSHQAKQWAEI
                     AAEDGAHGVLCLPPTMYRANRGEVIAHYEAVASAGLPVMVYNNPIDTKVDLTPDLLAEI
                     AQIDGVVAVKEFSGDVRRVLEIKEKAPGIEVVAGADDVTLEALLMGATGWFAGFPNVFP
                     AESALLYELATTGKLEEARALYEPLVAAFRWDSRTEFVQAIKLGMEQVGRYGGPCRPPR
                     GPLTDEHRAGVTADMARAIEALARRQAA"
     gene            8855..9871
                     /locus_tag="ACTIVE_RS02790"
                     /old_locus_tag="ACTIVE_0559"
     CDS             8855..9871
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017623947.1"
                     /locus_tag="ACTIVE_RS02790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_0559"
                     /product="proline racemase family protein"
                     /protein_id="WP_173092496.1"
                     /transl_table=11
                     /translation="MRSVRSITAVDSHTEGMPTRVVTGGVAPIPGATMAERRRYAVEHL
                     DGLRRFLVDEPRGHPAMSGALLQPPTRSDADWGVVYIEVSGFLPMCGHGTIGVATVLVE
                     TGMVEVTEPETIVRLDTPAGLVEARVAVRDGVAENVTLRNVPAFALRQDAVVDVPGLGE
                     VRYDMAYGGNFYAITELERLGLPFDRARKDDILKAGLAIMAAINETDRPVHPGDPLIGG
                     CKHVQFLAPGSDARHSRNAMAIHPGWFDRSPCGTGTSARMAQLHARGELPLHTEFVNES
                     FIGTRFTGRLVGTTEIGTAEAGGRPAVIPEFTGRAWITGNATYLLDPADPFPEGFVL"
     gene            10012..11499
                     /locus_tag="ACTIVE_RS02795"
                     /old_locus_tag="ACTIVE_0560"
     CDS             10012..11499
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890372.1"
                     /locus_tag="ACTIVE_RS02795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_0560"
                     /product="amino acid permease"
                     /protein_id="WP_173092499.1"
                     /transl_table=11
                     /translation="MPKTPPSADPAARGLFTRAGVFRLKPVDSSEEETAGGLRRTMGLW
                     QLVALSLGGLVGAGVFSLAGVVAHDDAGPGVMISFLIAIIASSAAALCYAEFAGLIPKA
                     GSAYTYSYAALGEAIGWAIGWDLLLEYTAIVAVVAIAISGYLSYILDQVGLDIPHWALG
                     APGTGSGHKVDLFAALLCLLLAFVLSRGTKESARFETILVVVKLGIVALVVIAGAFHIS
                     GGNFSPFLPFGIGGAISGAATTFFAVYGYDAMSAAAEESAEAKKVLPKAIVISLAIAAV
                     IYLLVCIVLLGMQDYRHIDVKSPFSSALASVGLAGLGTVVAVGAVIGITTSALANMLAV
                     TRVWFSMSRDGLLPAYFAKNHPKRQVPDRVIWLVGIGSAVIAGFLPIKEAADLTNIGIL
                     MAFIVVAVAIMVMRRTRPDLPRSFRTPWVPLVPLVGIGFSIWLIANLDWVTWVRFVVWM
                     LLGLIVYAFYGYRNSVENRGPGTVRTTPQGGDEGSTS"
     gene            11496..12893
                     /locus_tag="ACTIVE_RS02800"
                     /old_locus_tag="ACTIVE_0561"
     CDS             11496..12893
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017556434.1"
                     /locus_tag="ACTIVE_RS02800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ACTIVE_0561"
                     /product="aldehyde dehydrogenase (NADP(+))"
                     /protein_id="WP_173092501.1"
                     /sec_met_domain="Aldedh (E-value: 7.7e-39, bitscore: 132.5,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPDQAVAAAVSAAAGWAAAPPHERAEGLTAIADALEAARAELVA
                     LADEESRLGETRLNGELTRTTFQLKLFADQVREGAFYDARIDRPDPHWPSGPRPDLRRY
                     RTALGPVLVFAASNFPFAFSVAGGDTASALAAGCPVVVKAHPGHPRLSRRTAEIIAGAG
                     LPDGVFGLIEGEAEGVEALRHPGIAAAAFTGSEKGGLALAKIAAERPTPIPFFGELGSV
                     NPTVVTPRAAATRADEIAQGYAASLTLGAGQFCTNPGLLFAPEALVDEIAERLDGVAAA
                     PMLNDRIASGFLAVSDVLGGRPGVRRVVWPEDGASLAPRLLTMDLAAFRADADAAQECF
                     GPLGLIVTYDDLADVAEAVAALPGQLTTSLHAEQDETGDLAALTGVLADRSGRVLWNQW
                     PTGVAVSYAMEHGGPYPATTAPATTSVGTAAIERFLRPVAFQGWPQELLPPPLRDDNPW
                     KVPQTVH"
ORIGIN
        1 gccggccaca cgccctgcgg ccgcaggatc acgatgacga tgagcagcag cgcgaagaac
       61 agcccccggt actcctgcac ggtccgcagc gcctcgggca gcgcgacgat gacgatcgcg
      121 ccgaccatca ccccgggccg gctgcccatc ccgccgatga tcaccacgag caggatcatc
      181 agcgaggtca ggaacgtgaa gctggacggg tcgacggtgc cgagctgcgc ggcgttcagc
      241 ggccccgcga ccgcgccgac cgcggcgccg aggacgtagg cgagcagctt cactcgccgg
      301 gacgggacgc cgaccgcctc cgcggcggtg tcgtcggacc gtatcgcccg ccacgcgtac
      361 gccagccgcg tccgcgccag cagtcccgtc aggacgagca cgacgacgaa gaacgcgagc
      421 gcgaggtaga agaagccggc gggcgtgacg atctggcggc cggcgaccga gaccggcggg
      481 atcccggtca gcccgttcgg gccgccggtg acgtccaggt tcaccacggt gatccggatg
      541 atctcgccga agccgagcgt gacgatcgcg aggtagtcgc tgcgcagccg cagcgtcggg
      601 tagccgatca cgacgccggc ggcggccgcg gcgagcaccg cggcgggcag cgtcagccag
      661 aagttccagt ccagcttcag catcagcagg ccggaggtgt acgcgccgat cgcgaagaac
      721 gccgcgaagc cgaggtcgag cagcccggcg tagccgacga cgacgttgat gccgagcccg
      781 aggatcgcgt agatgaggat cgtcccggcg acggtgacct ggtagtcgtc catcacctgc
      841 ccgccggcga gcgcgaccac gatcagcagc ggccagccgc cgtgccgcag cgcggggttc
      901 cggaggagcg cggcccgggc cttcatgcgc gctccacgac gcgctcgccg aacagcccgg
      961 tcggccgcag cgccagcacc gcgatcagca gcccgaagat gatcacgtcg gtccagcggg
     1021 acgagacgta cccggcggcg aacgactgga cgagcccgat gcacaccccc gcgaccatcg
     1081 tccccggcag gttcccgatc ccgccgagca cggcggcggt gaacgcgcgc agcccgatca
     1141 ggaagcccat gccgaagctg atctgcacgt agtacagccc gtacatgacg ccggcggcgc
     1201 ccgcgagcat ggacccggcg aagaacgtga cgaggatgag ccgctcgacg ttgatgccct
     1261 gcaggcgcgc ggcgtcgcgg tccatcgcca gcgcccgcat cgccgtcccg gtgacggtgc
     1321 gggtgacgaa cagccacagc cccgccatca gcgccaccga cagcagcacc agcgcgagct
     1381 gcccgtaggt gacgcggacg gcgccgctga agatccggcc gccgtccagc acccccggat
     1441 aggacttgaa ccgggcgtgc gtcaggtcct tcacgccctc ctccagcgcc agcgacaccc
     1501 cgatcgcgga gatcagcagc gccagccggg gcgaggacag cagcgggacg taggcggcgc
     1561 gggcgatccc ggtgccgacc acgccggtgg tgagcgcgcc gacggccacc gcggcgagca
     1621 gggcgggcca cgccgccccg ccggtgacgc cgagcgtggt cagcaccgcg tacccggcga
     1681 acgccccgat catgaacacg tcgccgtgcg cgaagttgat cagccgtacc acgccgtaga
     1741 tcatcgagta gccgagcgcg atcagcgcca ggaacgcccc gatggtcagg ccgttcacca
     1801 ggtactggac gaactcgctc atgccgccgc gctcacgagg ccttggcgtc cacccaggcg
     1861 ccgctcctgt cgagcttctt gaaggcggtg aacgcgccgt tctgcacgtg gacggtgatg
     1921 tacagcgggt cggtccggtc gcccttcgcg tcgaaggtga tggggccggt gatgccgggg
     1981 aagtccttga cgccgtgcag gcccttgatg atgtcggcgc ccttcgtccc ggtctgcccg
     2041 atgaccttcg cgaggacctt gaccgcgtcg tactcgtaga cggagaacgg cccggggtcg
     2101 gcgccgttct tcgccttgta ggccgacacg aatccggacg ccgccggcag gtccttggcg
     2161 agcggcgcgg tcgtggcgat gtagccgtcc gcggccgaac cggccgtctt caggacggtc
     2221 gcgtcggtcg tcgcgtcccc gcccatcagc gtgaacttca ggccgagctg cttgcgctgc
     2281 ttcatcagca ggcccgcctc ggcgtagtag ccggtgaagt acaggacgtc cggcttcgtt
     2341 gaggcgatct tcgtcagaac cgggctgtag tcggactggc cgggctgcag cgcgtcctcg
     2401 tagacgacct gcccgccgga ctgcttcacc gagttcgccg ccgcgtccgc gaggcccttg
     2461 gcgtaggtgg tgttgtcgtg cagcagcgcg atccgcttcg cgccgagcgg gccggtcatg
     2521 aacttcgccg cgaccaggcc ctggttgtcg tcgcgcccgc aggtccggaa caccttgccc
     2581 ttgccgctgt cggtgagcga cgggttggtg gaggcgtcca tgacgaacgg cacgctccgc
     2641 cgcccgtaga tcgggatcgc gggcaccgcg gcacccgagc agtacccgcc ggcgaccgcc
     2701 acgacgccgc tgttcagcag cttctgcgcg gcctgcgcgc cctgctgcgc gctgcactgg
     2761 tcgtccgcct ggacgatctt gatcttcttg cccttcaccc cgccggcctt gttgacctcg
     2821 tcggcggcga cccgcgcggc ggcgaggatg tcctggcccg cggaggcgga gtcgccgctc
     2881 agcggcgccg gaacgccgat cttgacgtcg ccggagccgc cggagccgcc ggagccgccc
     2941 gatccgcagc cggcggcgag cgggaccagc agcagcccgg cgccggccgc cgcgagcccg
     3001 tgcgatcgcg ctccgccgcg ccgtcgtctt ctggccgtca tcgccgctcc ctcgctcgtc
     3061 aggcgggttg gcaaaagcgt gatccgactg cggacggccg tcgagacgac gaagcatgcg
     3121 atctcatgtc gtgatcggta agcaccgctt gcccttccgc cctggacggc gcggggaccg
     3181 ggtcgcgagg atcggcgcat ggccgacgtc ctgctgctgt ccgccgccga cgtgcgcgcg
     3241 gtgttcgacc tgccggccgc gatcgagtcg cagcgcgccg cgttcgcggc gctcggcacc
     3301 ggcgaggcgc ggctcgcgcc gcgggtgctg ctggacgggc cggacggcgc ggtggcgttc
     3361 agctacgttt cgcggcttcc cgggacgggc gcggtcgcga agttcggcag cgtcacgccg
     3421 ggcaacgccg cgcgcggcct gccgagcgtc gcggcgctgg tcaccgtgca ggacccggtg
     3481 gacgggcggc ccgtcgcgat catcgagggc gaggcggtca cgacgctgcg gacgtcggcg
     3541 gcgagcgcgg tcgccgccga ccatctcgcg gccccgggcg cgtcccggct cgccgtgatc
     3601 ggctgcggcg tgcagggccg cgcgcacgtg cgggcgatgc cgcgcgtgcg cccggtcgag
     3661 cgggtgaccg tggcctgccg caaccccggg acatgccgcg ccgccgccga gctggccgcg
     3721 gagctggagc tcccggtcga ggggaccggg gacgcccgca cggccgtcgc cggcgcggac
     3781 ctcgtcgtca ccgccaccac cagcgcggag ccggtcgtcc tcggcgagtg gctcgaaccg
     3841 ggctgcacgg tgctgagcgt cggctcgttc gcgccggacc gctgcgaggt cgacggcgcg
     3901 ctcctcgacc gcgcggcggc cgtcgtcgtg gacgacgtgg acaccgccgc gcggcaggca
     3961 ggcccgatcg tggcggggct gcgcgacggg cggctgagcg aggaccggat ccggcccctc
     4021 ggcccgatcg tcgccgggct cgcgcccggc cgcgccgcgg ccgacgacgt cgtcttctac
     4081 aacagcgtcg gtctcggcgt gcaggacgcg gcggccgcgg ccgtcatcgt cgagcgcgcc
     4141 cgcgccgccg gggcgggccg gatcgtcgcg ctgtagcggg ccgatccgga cggcacgccg
     4201 cgccgtcggt aaactacgtg ttcgttaaag cgaacgcaag agatgcgggc gggcggcgtc
     4261 ccgcgggcga agggggcggg cacgtgggcg gtccgggcga ttcggtgcgg gacgtgctgg
     4321 cgggcaacct gcgccgcgcg cggctggagc tcgggctgtc gctgtcggag ctgtcgcgcc
     4381 ggtcgaagat cggcaaggcg acgttgtcgc agctggaggc gggtgcgggc aacccgacca
     4441 tcgagacggt gttcagcctg tcgcgcgctc tggaggtgcc gatctccgac ctgctggacc
     4501 accaggagcc gtccgggctg accgtggtgc gcggcgcgga cgtcgaggtg ctgcgcggcg
     4561 agggcgtcga cctgcgcccg ctgcgcggga tcgagtccgg cggcgcgatc ttcgaggtgt
     4621 atgaccagca ggtcagggcc ggttcccggc aggactcgct cggccatgtc gggaccgagc
     4681 acaccatcgt gcaggcgggc cggctcggcg ttcgggtgga cgaccgggac gtggagctcg
     4741 ggcccggcga ctacgtgagc ttcgatgccc ggctgccgca cacctacacc gctctcgacg
     4801 ggcccgtccg ctccgtgctg ctcctgcagt accgctctga ccagcggctt cacgccgcac
     4861 cggcggagtc gccgcacctg gtcgagacgc cgtgacgccg gtctcatccg cgcattgaca
     4921 gcgcgccgcg ggcggacgta ctctcgggct cgttcggttt aacgaacgct ctggacggtg
     4981 acggcgcggc gggagggtcg atgacgcgga tcgtggtgct gggcgccggg atggtcggcg
     5041 cggcctgcgc ccgcgagctg gccctcgccg ggttcgccgt cacggtcgtc gaccggtccg
     5101 gcccggccgc gggcaccacc gcgcacggcg agggcaacgt cctcgtctcc gacaaggggc
     5161 ccgggccgga gttggaactg gcgaagctgt cccgcgagct gtggcccgcg atcctggacg
     5221 gcgacccgaa cgcgggcgcc gccgaatggg accccaaggg cggcatcgtc gtcgccacca
     5281 cgcccgaggg cgccggcgcg ctcgccgagt tcgccgaagg gcagcgcaag gccggtgtca
     5341 ccgccgagga gatggacgcc gccgcgctcg ccgccgccga gccccacctc acccgcgacg
     5401 tcgcgatggc cgtccactac tccgaggacg cgcaggtgca gcccgccggc gccgcgaccg
     5461 cgctgctggc cgccgccgtc cgcgccggcg ccgggctgcg caccggctgc gaggtgctcg
     5521 gcgccgtccg ccgcggcggg cggatcaccg gtgtccgcac ctccaccggg acgatcgagt
     5581 gcgacgcggt cgtcaacgcc gccggaccct ggtccgggga ggtggcgaag cggctcggcg
     5641 tccggctcgg cgtccggccc cgccgcggcg aggtgctggt gaccgcgccg atgccgccga
     5701 ccgtcttcca caaggtctac gacgccgact acgtgggcgc cgtcggcagc gccgccgagg
     5761 acctccaggc gtccgcggtc gtcgaggcca cccgcggcgg cacgatcctg ctcgggtcgt
     5821 cgcgccgccg cgtcgggttc gacgaccgga tccgccccga ggtgctgtcg gtcatcgccg
     5881 ccaaggcgct gcggctgttc ccgatgctgg ccggcgtgcc ggtgatccgg gcctacggcg
     5941 ggttccgccc gttcgtcccc gaccacctgc cggtcatcgg cgccgacccg gaactggacg
     6001 gcctctggca cgccaccggc cacgagggcg ccgggatcgg gctgtccgcc ggcaccgccg
     6061 ccgtgctgcg cgacctgatg ctcggccgcg agcccgcgat cgacgcggcg ccgttccggg
     6121 cggaccggcc cgccgtccag tccgaaggag agaacctgtg agcgcgagac tcgtgcccgc
     6181 ggccggcgac gcgtccgggc gccgccccga cgtcccgctg cggatcaccg tggacggcga
     6241 gcccgtcgac ggcgtcgccg ggcagaccat cgcgggcgtg ctgctcgcgt ccgggcgccg
     6301 cacctggcgg tccgggccgt ccggcgcccc gcgcggggtg ttctgcggga tcggcgcctg
     6361 cttcgactgc ctcgtcaccg tcaacggcgt ccgcgacgtg cgggcctgcc gccgccgcgc
     6421 ccacgacggc gacgccgtcg ccacccagtc gcgcggcgag gacgcccgat gagccgccgc
     6481 gtcgtggtcg tcggcgcggg ccccgcgggg ctcggcgccg cggcgggcgc gctgcgcgcc
     6541 ggtgccgacg tgacgctgat cgacgcgtcc gagcagcccg gcggccagta ccaccggatg
     6601 ctccccgacg cgttcgccgc cgcggccccc ggacgcctgc accacggctg gcagggcttc
     6661 gagcggctgc gcgaccacgt cctgcggcac ccgcggtgcg actggtggcc ggagagcacc
     6721 gtctggtcga tcgaacggca cgacgagggg gcgccggccg tccacgtgct gcgcggcgag
     6781 gccgacgcgg ccggccgcga acgccgcgtc ctgcgcgcgg acgccctggt cctcgcgccc
     6841 ggcgctcacg accgcgtcct gccgttcccc gggtgggggc tgcccggcgt ctacaccgcc
     6901 ggcgccgcgc aggcgctcgc caaaggggag cgcctcgtcg tcggcgaccc cgtgctgatc
     6961 gccggctctg gaccgttcct tctcccggtc gccgcgtcgc tgatcgaggc cggcgccacc
     7021 gtcctggaag tgctggaggc caaccccgcc gcgaccgtgg cgcgcggctg ggcccgccgc
     7081 ccctgggagc tggcctcgca ggccggcaag gccggggagc tggccgagta cgcggggctg
     7141 ctggcccggc accgcgtccc ctaccggacg ggccgcgccg tgatcgaggc ccggggcgac
     7201 gggcgcgtcg aagaagcggt cacggcgcgg ctgcgtcccg actggtcggt cgtccccggc
     7261 accgagcgca ccgtcccggt cgacgcgctg tgcgtcaccc acggcttcag cccgcagctc
     7321 gaactgcccg tcgcggcggg ctgcgcgctc gcccgcacgt ccggcggctc gttcaccgag
     7381 gtggacgccg accagcgcac caccgcgccg ggcgtctacg cggccggcga gatcaccggc
     7441 atcggcgggg cgcccgccgc ccgcaccgag ggcctgctcg ccggctggat cgccggggga
     7501 ggggaccccg ccgcccgcga ggccggcgcg ctgcgccgcc gccgcgatca ggcccgcgcg
     7561 ttcgccgccc gcctagcggc cgcgcacccg atcggcgcgg cctggcccgg ctggctgcgc
     7621 gacgagaccg tcgtctgccg ctgcgaggag accacgtacg gctccctgtg ccgtgcggcc
     7681 ggcgacgagg cgagcgggtc cgcccgcgcg gtcaagctcg gcacccgcgc cgggctcgga
     7741 ccgtgccagg cccgcatttg cggccccacg gtcgccgaac tgctttccgg caaggtgccc
     7801 ggggcgaacc cccaccaccg gcccatcgcc cagcccatca ggctcggcga gctcgcaagt
     7861 ccccctaccg agaacaccgg taacaccaag aaccgcagga accccgacaa gaaagagagc
     7921 gcccgatgag cgacaccaag ctcctgagcc tcggcggcgt catcgttgcg acggcgctgc
     7981 cctactacga ggacgcctcg gcccccgccg ggctcgccgt cgactacgac aagtacgccg
     8041 agcactgccg ctggctcgtc gacaacggct gccgcggcgt cggaccgaac ggctccctcg
     8101 gcgagtactc gtcgctgacc gacgacgagc gccgccgcgt cgcgcgcacc gccgtcgagg
     8161 ccgtcggcaa ggacggcgtc gtcgtggtcg gcgtgcacgg ccccggctcc caccaggcga
     8221 agcagtgggc ggagatcgcc gccgaggacg gcgcgcacgg cgtgctgtgc ctcccgccga
     8281 ccatgtaccg ggccaaccgc ggcgaggtca tcgcccacta cgaggccgtc gcctccgccg
     8341 ggctgcccgt catggtctac aacaacccga tcgacaccaa ggtcgacctc acccccgacc
     8401 tgctcgccga gatcgcgcag atcgacggcg tcgtcgcggt caaggagttc tccggcgacg
     8461 tccgccgcgt cctggagatc aaggaaaagg cccccggcat cgaggtggtc gcgggcgccg
     8521 acgacgtcac gctcgaagcg ctgctgatgg gcgccaccgg ctggttcgcc ggcttcccga
     8581 acgtgttccc cgccgagtcc gcgctgctgt acgagctggc caccaccggc aagctggagg
     8641 aggcacgcgc gctgtacgag ccgctcgtcg ccgcgttccg ctgggactcg cgcaccgagt
     8701 tcgtccaggc gatcaagctc ggcatggagc aggtcggccg gtacggcggc ccgtgccgcc
     8761 cgccgcgcgg cccgctcacc gacgagcacc gcgccggcgt caccgccgac atggcccgcg
     8821 ccatcgaggc cctcgcccgg cggcaggccg cctgatgcgc tcggtccggt cgatcaccgc
     8881 ggtcgactcg cacaccgagg gcatgccgac ccgcgtcgtc accggcggcg tcgcgcccat
     8941 cccgggcgcg acgatggccg agcgccgccg gtacgccgtc gagcacctcg acgggctgcg
     9001 ccggttcctg gtggacgagc cgcgcgggca ccccgcgatg agcggcgcgc tgctgcagcc
     9061 gcccacccgg tcggacgccg actggggcgt ggtgtacatc gaggtcagcg ggttcctgcc
     9121 gatgtgcggg cacggcacca tcggggtcgc gaccgtgctg gtcgagaccg ggatggtcga
     9181 ggtgaccgag ccggagacga tcgtccggct ggacaccccc gccgggctcg tcgaggcccg
     9241 cgtcgcggtc cgcgacggcg tcgccgagaa cgtcacgctc cgcaacgtcc cggcgttcgc
     9301 gctgcggcag gacgcggtcg tggacgtgcc gggcctcggc gaggtccgct acgacatggc
     9361 gtacggcggc aacttctacg cgatcaccga gctggagcgg ctcgggctgc cgttcgaccg
     9421 ggcccgcaag gacgacatcc tcaaggccgg gctggcgatc atggcggcga tcaacgagac
     9481 cgaccgcccc gtgcaccccg gcgacccgct gatcggcggc tgcaagcacg tccagttcct
     9541 cgcgcccggc tcggacgcga ggcactcgcg gaacgccatg gcgatccacc cgggctggtt
     9601 cgaccgctcg ccgtgcggca ccggcacgtc cgcgcggatg gcgcagctgc acgcgcgcgg
     9661 cgagctgccg ctgcacaccg agttcgtgaa cgagtcgttc atcggcaccc ggttcaccgg
     9721 ccggctcgtc ggcaccaccg agatcggcac cgccgaggcg ggcggccggc cggcggtgat
     9781 ccccgagttc accggccgcg cctggatcac cggcaacgcc acctacctgc tcgaccccgc
     9841 cgatccgttc cccgagggct tcgtcctctg acggaaccgg cttctcccgt tccggggccg
     9901 cgggccccgt ccgggccctt cacggcggcc ggccgcaccg ggccggccgc cgcgcacccc
     9961 acccctggta ttcccctgac ccatccggga gggaccgtca tgtcccaagc catgccgaaa
    10021 acgccgccgt cggccgatcc ggccgcgcgc ggtctgttca cccgagcggg cgtcttccgc
    10081 ctgaagccgg tcgactcctc ggaggaggag accgccggcg gcctgcgccg caccatgggc
    10141 ctctggcagc tcgtcgcgct cagcctcggc ggcctcgtcg gcgccggcgt gttctcgctc
    10201 gcgggcgtcg tcgcgcacga cgacgccggc cccggcgtga tgatctcgtt cctcatcgcg
    10261 atcatcgcca gcagcgccgc cgcgctctgc tacgccgagt tcgccggcct catcccgaag
    10321 gccggctccg cctacaccta ctcctacgcc gcgctcggcg aggcgatcgg gtgggcgatc
    10381 ggctgggacc tgctgctgga gtacaccgcg atcgtcgcgg tggtcgccat cgcgatctcc
    10441 ggctacctgt cctacatcct cgaccaggtc ggcctcgaca tcccgcactg ggcgctcggc
    10501 gcgcccggca ccggctccgg ccacaaggtc gacctgttcg ccgcgctgct gtgcctgctg
    10561 ctggcgttcg tgctgtcgcg cggaacgaag gagtcggcgc gcttcgagac gatcctcgtc
    10621 gtcgtcaagc tcggcatcgt cgccctggtc gtgatcgcgg gagcgttcca catctccggc
    10681 ggcaacttca gcccgttcct gccgttcggc atcggcggcg cgatctccgg cgccgccacc
    10741 acgttcttcg ccgtgtacgg ctacgacgcg atgagcgccg cggccgagga gagcgccgag
    10801 gccaagaagg tgctgccgaa ggcgatcgtc atctcgctcg ccatcgccgc ggtcatctac
    10861 ctgctggtct gcatcgtgct gctcggcatg caggactacc ggcacatcga cgtcaagagc
    10921 ccgttctcca gcgcgctcgc ctccgtcggc ctcgccggcc tcggcaccgt cgtcgcggtc
    10981 ggcgccgtca tcggcatcac cacctccgcg ctggcgaaca tgctcgccgt cacccgcgtc
    11041 tggttctcga tgagccggga cgggctgctg cccgcctact tcgccaagaa ccacccgaag
    11101 cggcaggtcc ccgaccgcgt catctggctg gtcgggatcg gctcggcggt catcgccggg
    11161 ttcctgccga tcaaggaggc cgcggacctc accaacatcg gcatcctgat ggcgttcatc
    11221 gtggtcgccg tcgcgatcat ggtgatgcgc aggacccggc ccgacctgcc gcgctcgttc
    11281 cgcaccccgt gggtgccgct ggtgccgctg gtcggcatcg gcttctcgat ctggctgatc
    11341 gccaacctcg actgggtcac ctgggtccgg ttcgtggtct ggatgctgct cggcctgatc
    11401 gtctacgcgt tctacgggta ccggaactcg gtggagaatc ggggaccggg gaccgtccgc
    11461 accaccccgc agggcgggga cgaagggagc acctcatgac acccgaccag gccgtcgccg
    11521 ccgccgtgtc cgccgcggcc ggctgggccg cggcgccgcc gcacgagcgc gccgagggcc
    11581 tgaccgcgat cgcggacgcc ctggaggccg cccgcgcgga gctggtcgcc ctcgccgacg
    11641 aggagagccg cctcggcgag acccggctga acggcgagct gacccgcacc accttccagc
    11701 tgaagctgtt cgccgaccag gtccgggagg gcgccttcta cgacgcccgc atcgaccgcc
    11761 ccgacccgca ttggccgagc ggcccccggc ccgacctgcg ccgctaccgg acggcgctcg
    11821 gccccgtgct ggtgttcgcg gcgagcaact tcccgttcgc gttcagcgtc gcgggcggcg
    11881 acaccgcgtc cgcgctcgcc gccggctgcc ccgtcgtggt caaggcgcac cccggccacc
    11941 cccggctgtc gcgccgcacc gccgagatca tcgccggcgc ggggctgccg gacggggtgt
    12001 tcgggctgat cgagggtgag gcggagggcg tcgaggcgct gcggcacccg ggcatcgccg
    12061 ccgcggcgtt caccggctcg gagaagggcg gcctcgccct cgccaagatc gcggcggagc
    12121 ggccgacccc gatcccgttc ttcggcgagc tcggcagcgt caacccgacc gtggtgacgc
    12181 cgcgcgccgc cgcgacgcgg gccgacgaga tcgcgcaggg ctacgccgcg tccctcaccc
    12241 tgggcgccgg gcagttctgc accaaccccg gcctgctctt cgcgcccgag gcgctggtgg
    12301 acgagatcgc cgagcggctg gacggcgtcg ccgccgcgcc gatgctgaac gaccgcatcg
    12361 cgtccggctt cctggcggtg tccgacgtgc tcggcggccg tcccggcgtc cgccgcgtcg
    12421 tgtggcccga ggacggggcg tccctcgccc cgcgcctgct gaccatggac ctcgcggcgt
    12481 tccgcgccga cgccgacgcc gcccaggagt gcttcggccc gctcggcctc atcgtcacct
    12541 acgacgacct cgccgacgtc gcggaggccg tcgccgccct gcccgggcag ctcaccacct
    12601 cgctgcacgc cgagcaggac gagaccggcg acctcgccgc gctcaccggc gtgctcgcgg
    12661 accgcagcgg gcgcgtgctg tggaaccagt ggcccaccgg cgtcgccgtc agctacgcga
    12721 tggagcacgg cggcccgtac ccggccacga ccgcgcccgc caccacctcg gtgggcacgg
    12781 ccgcgatcga gcggttcctg cggcccgtgg cgttccaggg ctggccgcag gagctgctgc
    12841 cgccgccgct gcgcgacgac aacccgtgga aggtcccgca gaccgtccac taggcggaac
    12901 cgccggcccc gggacgagcc ggggccggc
//
