LOCUS       NZ_CP053564            25224 bp    DNA     circular CON 29-MAR-2024
DEFINITION  Pseudonocardia broussonetiae strain Gen 01 chromosome, complete
            genome.
ACCESSION   NZ_CP053564
VERSION     NZ_CP053564.1
KEYWORDS    RefSeq.
SOURCE      Pseudonocardia broussonetiae
  ORGANISM  Pseudonocardia broussonetiae
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Pseudonocardia.
REFERENCE   1  (bases 1 to 7177725)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-MAY-2020) College of Life Science and Technology,
            Central South University of Forestry and Technology, No. 498,
            Shaoshan South Road, Changsha, Hunan 410004, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013155125.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 06:16:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,087
            CDSs (total)                      :: 7,032
            Genes (coding)                    :: 6,962
            CDSs (with protein)               :: 6,962
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 19 of 70
            Pseudo Genes (incomplete)         :: 48 of 70
            Pseudo Genes (internal stop)      :: 6 of 70
            Pseudo Genes (multiple problems)  :: 3 of 70
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:38:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6268404
            Orig. end                         :: 6293628
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP053564.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Mo.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25224
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="14"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..25224
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25224
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15224](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15224
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            700..2958
                     /locus_tag="HOP40_RS30405"
                     /old_locus_tag="HOP40_30420"
     CDS             700..2958
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023418.4"
                     /locus_tag="HOP40_RS30405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30420"
                     /product="DUF3488 and transglutaminase-like
                     domain-containing protein"
                     /protein_id="WP_172165506.1"
                     /transl_table=11
                     /translation="MTLTAPRPLRAAPPPPPAPPAPGPVVRPLAPLLCAVAVLLAAAPV
                     SSVVQGWTWLGYAGGAVALVAVVGVVGALVPRVPAVAVALVQVAAVLGLLTALFTDDGV
                     ARVLPGPAALGDMGALLAGAGAQIDVGTAPVAATPEILFLVTAALGLLAVAVHLAVVGA
                     GAPAAAGVPLLAAFAVPAALADDLLPWWTLAVAALGFGVLLLAPDGNRRQIPGGAVLVA
                     GAAVVALLLGTATAFVGTAGRFDGGEDGTGRGAIGLSPFTALRGQLDQSEPTPLFEVRG
                     LAQPQYLRALTLSDYQAGIGWQATRPGPGVAPEGPFTQPGVPGDVVDVTVGNVGFRDYW
                     LPVYGAPLGIGGLAPDLFVYDEPSGIAYTARPQQQETWTERAFLPAPTTDLLRAAQGER
                     PAAIYANILGVDPRVTEIAQQVTAGAASDFDRAMALQEYFTGPDTAFTYDLATAPPAGD
                     DALVEFLTVGRVGYCEQFASAMAVMLRSVGVPARVAVGFTAGSPISDYRAVSTADAHAW
                     VEAWFPGIGWTTFDPTPLTDGRTITPPYVEAARAEAAGGGTGAGAVPAAPTGAAPTTAP
                     TTAPGEQPLDAAAPAPVAADPGLPLWPLFVVLGLVLVGLVPAAVRALRGRSRLAAAAAG
                     GTGAAGAAWDEIVATSVDRRVPVPATDTVRAAARRLVREHRLDAAAQDAVRAVVGAVEA
                     SWFGDRHPEPGELAGPVRVVRDGIAAGSPVSLRGRLLPRSVLVRPVRSAPEAPVTTSV"
     gene            complement(3041..3439)
                     /locus_tag="HOP40_RS30410"
                     /old_locus_tag="HOP40_30425"
     CDS             complement(3041..3439)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013674918.1"
                     /locus_tag="HOP40_RS30410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30425"
                     /product="DUF3040 domain-containing protein"
                     /protein_id="WP_172165509.1"
                     /transl_table=11
                     /translation="MPLSEHEQRLLEQIERALYAEDPKFASTVRGGRLRKPTRRRRMQG
                     VALFLLGLVMLVVGVVIQSLSGGGGGMIALIVLSVLGFVVMLGGSVLAVTSSGKAPAGS
                     GTPAEAEKEKNGFTGRMEERFRRRFEQD"
     gene            complement(3765..4481)
                     /locus_tag="HOP40_RS30415"
                     /old_locus_tag="HOP40_30430"
     CDS             complement(3765..4481)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013674917.1"
                     /locus_tag="HOP40_RS30415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30430"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_240157850.1"
                     /transl_table=11
                     /translation="MEAEVARAAERARSRGAEPRVLDVGGGSGAWAVALARLGCVVTVV
                     DNSPNALAALHRRARDAGVHGRVTPVQCDVDALADVAPAGGADLVLGHGLLEVVDDAPH
                     ALGALADATAPGGAVSVLVAGRHAAVLGRTLAGRLAEARALLTDPHGRSGPDDPLRRRL
                     DATELRALLDAAGLLPELVQGDGVLDGWVPGSVRDSGPAATRAVAELEVLAAARPALLE
                     LAARLHVLARRPLPAG"
     gene            4614..5468
                     /locus_tag="HOP40_RS30420"
                     /old_locus_tag="HOP40_30435"
     CDS             4614..5468
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1157: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011874870.1"
                     /locus_tag="HOP40_RS30420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30435"
                     /product="ParA family protein"
                     /protein_id="WP_172165512.1"
                     /transl_table=11
                     /translation="MQVVATLSLKGGVGKTTVALGLAGAAQQHGVRTLLVDLDPQANAT
                     IALDVGDTSATVADVLDDPRRSVLRRAIAPSGWGEGLDVMVGAEQTERHNHPDPGAKQL
                     SRLTRALGRLVDADEEDARDGGAEEHDLGPYRLVVIDCPPSLGQLTRSALAAAHRAVLV
                     TDPTMFAVSGVQRAFDAVQTERQRGNPDLQPLGVLINRVRPRNAEHEFRVAELRELFGP
                     LVFSGVLPDRSAVQQAQGACVPIQSWDTPGAREVSAVFTTLLGRVLRSERRPRAATAPP
                     PTR"
     misc_feature    complement(4649..4664)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 18.71"
                     /tool="antismash"
     gene            complement(6589..7005)
                     /locus_tag="HOP40_RS30425"
                     /old_locus_tag="HOP40_30440"
     CDS             complement(6589..7005)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099097.1"
                     /locus_tag="HOP40_RS30425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30440"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_172165515.1"
                     /transl_table=11
                     /translation="MTITTDRPVPAPRPAPVSRSALALLRQAADGLAEAHREHDPLRRY
                     PAAYLAALRAGAAVLAVRAAPQPRRGAPRAVWDILATVAPELGEWAAFFASCSATRAAA
                     EAGIARLVDQRGADDLLRQAEQFVGMVTESVRLR"
     misc_feature    7027..7042
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.98"
                     /tool="antismash"
     misc_feature    complement(7028..7041)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.4"
                     /tool="antismash"
     gene            complement(7064..7381)
                     /locus_tag="HOP40_RS30430"
                     /old_locus_tag="HOP40_30445"
     CDS             complement(7064..7381)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010231343.1"
                     /locus_tag="HOP40_RS30430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30445"
                     /product="hypothetical protein"
                     /protein_id="WP_172165518.1"
                     /transl_table=11
                     /translation="MSAFSRVFRSREPTPVQVRWLDGEPVEFQRRPARRGPRYLIVDVR
                     ERWIEQSPWPFPSPMPVGGDRLRCWRVEARSADEPDVPGREFVLRMRAGPGVWDLVRVP
                     E"
     misc_feature    7505..7520
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: strong, score: 27.38"
                     /tool="antismash"
     misc_feature    complement(7506..7519)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 23.11"
                     /tool="antismash"
     misc_feature    7506..7519
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 17.81"
                     /tool="antismash"
     misc_feature    complement(7598..7613)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.79"
                     /tool="antismash"
     gene            7609..8187
                     /locus_tag="HOP40_RS30435"
                     /old_locus_tag="HOP40_30450"
     CDS             7609..8187
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010231344.1"
                     /locus_tag="HOP40_RS30435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30450"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_172165521.1"
                     /transl_table=11
                     /translation="MTTAPARHIVEWGPSDLAARVDDALAVYVAAMGYPPSTARHRRTL
                     WLDHVRRPGWRAVGCVDDAGRLLGVAYGYTGAPGQWWFEEVSRGLRPRPQERFWLEDYF
                     ELTELHVHPDTQGGGLGEGLLRTLLAGATARRVLLSTPENGDGPTNRAWLLYRRLGFAD
                     VLRHHRFTGDARPFAVLGRDLPLPPAPPR"
     gene            8217..8873
                     /locus_tag="HOP40_RS30440"
                     /old_locus_tag="HOP40_30455"
     CDS             8217..8873
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013674910.1"
                     /locus_tag="HOP40_RS30440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30455"
                     /product="DUF3153 domain-containing protein"
                     /protein_id="WP_172165524.1"
                     /transl_table=11
                     /translation="MPSPRRRPALLLVLVLALLALSGCARVQAALAVQPDDTVRGQIVV
                     ATPETGPEDPGPVLTLPPDLAASVDVSEYRQEGYAGSLVRFSDLTFEQVSELITAAGPP
                     GEKVRLELRRAGNRVVVNGSVDLTTVDVDRSDFQLKIAFPGQVLDANGDADSGEVSWVF
                     EAGEVGDIEAVVAFDDPDAPSPFNWSLGLFLVVALAAAAVVLAAHRTRNPPVRQG"
     gene            complement(8978..9871)
                     /locus_tag="HOP40_RS30445"
                     /old_locus_tag="HOP40_30460"
     CDS             complement(8978..9871)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013674909.1"
                     /locus_tag="HOP40_RS30445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30460"
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="WP_172165527.1"
                     /transl_table=11
                     /translation="MKITDRIGGDQPVFSVEFMPPKDDAGEAELWNAIRRLEPLDPAFA
                     SVTYGAGGSSRDRTVRTTGRIASETTLVAMAHLTAVSHSVAELRHVIGEYAAAGIRNVL
                     AVRGDPPGDPLGEWVAHPEGLMYADELVSLVRSLGDFCVGVAAFPYGHPRSADEDSDLQ
                     RLVAKVRAGADFAITQLFLEPEGFLRLRDRLSAAGCEVPLLPGIMPLTTLRTLHRGPEL
                     SGAPLPPGLAERLERYAGDPAAFRRAGMDLTTELCARLLAEGVGGLHFYTFNRSTATTE
                     LVQRLGLGARRGVAVA"
     gene            10001..11110
                     /locus_tag="HOP40_RS30450"
                     /old_locus_tag="HOP40_30465"
     CDS             10001..11110
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013674908.1"
                     /locus_tag="HOP40_RS30450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30465"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_240157366.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1e-47, bitscore:
                     161.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTAPERVRAADDELSDAVEEVLAAYLERRGADTAAIDPAFGAA
                     TAALTEFVLSGGKRLRPTFAWWGWRGAGGSPDDAHAVGVLEAISALELIQACALVHDDL
                     MDASATRRGRPTVHVDFARRHAEAGWQGRPARFGAAAAILLGDLALVWADDLFRSSALP
                     VEALRRAAAPWEAMRTEVLGGQYLDVLHQSTGDTSPRAALQVDRYKTAAYTVERPLHLG
                     AAIADASPELVACYRRFGADIGIAFQLRDDLLGVFGDPAVTGKPAGDDLREGKRTLLLA
                     LALERAAEQGSRASAAAIEAALGDPDLDADGVDRVRGLLVDLGAEQAVEQRIAAMTGSA
                     LDALSTADIEEPAASRLSDLAVAATRRRR"
     gene            11113..12672
                     /gene="crtI"
                     /locus_tag="HOP40_RS30455"
                     /old_locus_tag="HOP40_30470"
     CDS             11113..12672
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686264.1"
                     /locus_tag="HOP40_RS30455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30470"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_172169526.1"
                     /sec_met_domain="DAO (E-value: 3.2e-15, bitscore: 55.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVTGPTDHVVVVGAGFAGLTTALHLLGAGRRVTVVERGEHPGG
                     RAGRLDLQTASGTYQVDTGPTVLTMPDLLDEAFGAVGEKVSERLDLVELDPAYRTHFAD
                     GSTIDVHTDAGAMEAEVRAVCGPDAAAGYVRMREWLGKLYRAEIDTFIGANFDSPLNLL
                     GPDLVRLAALGGFGRLGPRVEGFLPDERLQRIFSFQALYAGVPPQTALGAYGVIAYMDT
                     IAGVHFPKGGMRSVGQALADAAVAAGAEILYGRTVTGLERGAGRVTAVRHRATDDPLGA
                     SDRLAADSFVLTPDLPVVHDLLGRAPRRVVPLRYSPSAVVLHAGLRTSRPEAAHHTISF
                     GSAWRETFREIIDDGRLMSDPSLLITRPTATDPSLAPDGRDLLFVLAPCPNLEAGPIDW
                     ERVGPAYRDELLGVLEARQHPGLDGIEGDIEVSDLVTPADWAAQGMAAGTPFSAAHTFA
                     QTGPFRPRNLVRGFENVVLAGCGTTPGVGIPPVLLSGRLAAARITGPAPTTGRGRRVPT
                     GG"
     gene            12701..14260
                     /gene="mptB"
                     /locus_tag="HOP40_RS30460"
                     /old_locus_tag="HOP40_30475"
     CDS             12701..14260
                     /codon_start=1
                     /gene="mptB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013674906.1"
                     /locus_tag="HOP40_RS30460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30475"
                     /product="polyprenol phosphomannose-dependent alpha 1,6
                     mannosyltransferase MptB"
                     /protein_id="WP_240157367.1"
                     /transl_table=11
                     /translation="MTAQPSSPVDRSESPDRAVTAPAGSTPRASAWRARLGSPPRGPLV
                     LGVVASLLMVLGGFGAGGVLVDDPLLTNSPLGFWRYGHGREIANSLIYLGVGLLAWAWV
                     RLGREVLARRVGGRAVLTTATAWLLPMLVAPPLFTRDVFSYLAQGALPLHGFDPYAVGP
                     DALPGIFTDNVHYFWQDTPAPYGPLFILYAKSVAWLAGDQIILGVVLMRLALAVGLVLL
                     VRALPELSRRMGGRPALALWIVVANPVMVIHMVGGGHNDLLVMGLLATAALSALRGQHA
                     WGIVLATLAMAVKASAGVALPFLVLVWAGTMAGSVLARTLRATAYGIAVFVPVFALCTV
                     AAGVGLGWLPALSAPSMIVNWMSLPTGAGQLVHSVVSIFGPVSMQPFVNAGRAVGALIL
                     LVIAVHQWWASRDGGPDAMRRAGIVLLAVALLSPTTLPWYVSWGMALLAMVDWTPRALQ
                     VLVFFSLWLMIVYYPDGEAALYDLAVLGIGAALSALAAVSLLRPDPLGLARRPVGADPV
                     VR"
     gene            14250..15224
                     /locus_tag="HOP40_RS30465"
                     /old_locus_tag="HOP40_30480"
     CDS             14250..15224
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016700029.1"
                     /locus_tag="HOP40_RS30465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30480"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_172165533.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.7e-118,
                     bitscore: 392.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.4e-65,
                     bitscore: 219.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGSAELDAAGITDPALRAAYATCRRLNAAHGRTYFLATRLLPPD
                     RRPAVHALYGFARYADEIVDDLGDDRPVAEKAAELDALTAGLHAALDGAPTDVPVLAAL
                     GDTARRYGIDRAHFTDFMTSMRMDTHVTSYATDADLAVYVHGSAAVIGLQMLPVLGTTV
                     PLEEATPPATALGVAFQLTNFLRDVGEDLDRGRVYLPADELAAFGVDRELLAWCRAHRR
                     ADPRVRRALAHLVARTRGTYRRAAPGIAMLEPVSRACVGCAFALYQGILDEIEAAGYAV
                     LHRRVAVPNRRRLGVALPGLARAVAARRPGERPARTPSPARGA"
     gene            complement(15193..15558)
                     /locus_tag="HOP40_RS30470"
                     /old_locus_tag="HOP40_30485"
     CDS             complement(15193..15558)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013674904.1"
                     /locus_tag="HOP40_RS30470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30485"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_240157368.1"
                     /transl_table=11
                     /translation="MSEVSVLADDVETLPVAEVATLLNQPVSRVHQLVRDGQILSLRRD
                     GEVVVPAAFFSPGEERAEVVKGLPGTITVLRDGGYSDEDILRWLFSVDDSLPGSPMSFL
                     TEGRHREIKRRAQAMAF"
     gene            15638..17437
                     /gene="pknB"
                     /locus_tag="HOP40_RS30475"
                     /old_locus_tag="HOP40_30490"
     CDS             15638..17437
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155384.1"
                     /locus_tag="HOP40_RS30475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30490"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_172165536.1"
                     /sec_met_domain="Pkinase (E-value: 2e-44, bitscore: 150.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAPPAALLDARYRLGPVIARGGMSIVYRGTDTRLDRPVAIKVME
                     PRLAADPAFRTRFEREARSAARIDHPAVVDVYDQGRHVDDSGGHGPEPVLFLVMELVEG
                     ATLRDVLRMRGQLGVPGAVAVLDRVLAGLAEAHRLGLVHRDVKPENVLISHTGEVKVAD
                     FGLVVAAAQAGASHVGTIMGTVAYLSPEQVATGSADARSDVYAAGILLYELLTGTPPFT
                     GDTAISVAFRHVNDRVPPPSLIAGDVPPELDALVLRATDRDPAARPADAGALLGELRRV
                     AHRLEVPRVPVPAPPRPAQHATEPVTHPGPVVMPGPRGTQALPAGPPRGATSTDLAGPP
                     AGGTLHGGAGDPFPDHRRARRRSRRAFAVGIALVLVLALVVGAVAWWMGSGRWTQVPAL
                     VGVQQTAAAELLDDYGLVTGPATTTFDNAAPAGAVLAVDPPVGAQLLRGEIVTLTVSTG
                     RPVVPPVEAGTDVAGAEQLVRDAGLTPTRDSSDAEFSDSVPEGAVIRTEPPAGQAVDIG
                     GAVTLVVSRGVEPPPAPARVSVPMVVGQTASAAQALLDELGLSTVVQSTLPFALNEDPT
                     VIGQSPAAGTVVEEGTQVVLDTL"
     gene            complement(17451..18839)
                     /locus_tag="HOP40_RS30480"
                     /old_locus_tag="HOP40_30495"
     CDS             complement(17451..18839)
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013674902.1"
                     /locus_tag="HOP40_RS30480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30495"
                     /product="3-deoxy-7-phosphoheptulonate synthase class II"
                     /protein_id="WP_172165539.1"
                     /transl_table=11
                     /translation="MNWTVDAPVEVLPELPPLPADLRSRLDDALSRPAAQQPDWPDAAE
                     VAHVRTVLESVPPVTLPPEVDRLQSRLADVANGKAFLLQGGDCAETFVDNTEPHIRATI
                     RTLLQMAIVLTYGASTPVVKVGRIAGQYAKPRSSPVDALGLPSYRGDIVHSIVADPEAR
                     RADPSRMVRAYANASAAMNLVRALTATGMADLTTVHDWNKDFVRTSAAGERYEAVAAEI
                     ERAVRFMDACGVDDHNLHSVEFYASHEALLLDYERAMLRMDTTREEARLYDLSAHFLWI
                     GERTRQLDGAHIAVAELLSNPIGLKIGPTTTPELAVEYVERLDPKGAPGRLTLISRMGN
                     GKVRDVLPAIVEKVEASGHKVIWQCDPMHGNTVESTSGYKTRHFDRIVDEVQGFFEVHR
                     GLGTHPGGIHVEVTGEDVTECLGGAQEISDADLGGRYETACDPRLNTQQSLELAFLVAE
                     MLRG"
     misc_feature    18933..18948
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.71"
                     /tool="antismash"
     gene            18934..19077
                     /locus_tag="HOP40_RS30485"
                     /old_locus_tag="HOP40_30500"
     CDS             18934..19077
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040511.1"
                     /locus_tag="HOP40_RS30485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30500"
                     /product="GPGG-motif small membrane protein"
                     /protein_id="WP_172165542.1"
                     /transl_table=11
                     /translation="MATILWILAVVLVVAGVLAIIRKQLVWGIVLIVVGLLVGPGGVSI
                     FT"
     gene            complement(19111..19602)
                     /locus_tag="HOP40_RS30490"
                     /old_locus_tag="HOP40_30505"
     CDS             complement(19111..19602)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075260.1"
                     /locus_tag="HOP40_RS30490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30505"
                     /product="polyadenylate-specific 3'-exoribonuclease AS"
                     /protein_id="WP_172165565.1"
                     /transl_table=11
                     /translation="MRFFYDCEFIEDGTTIDLVSIGVVGEDGREFYAVSTEFDPSRAGA
                     WVRANVLPKLPSPADPAWRSRSRLRADLLDFVTEPGGDVEMWAWIAAYDHVALCQLWGA
                     MPALPRALPRFTRELRQRWEDAGRPALPPPTADAHDALADARLNLRRWEAIESAVAARS
                     "
     misc_feature    19568..19586
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.21"
                     /tool="antismash"
     gene            19777..22017
                     /locus_tag="HOP40_RS30495"
                     /old_locus_tag="HOP40_30510"
     CDS             19777..22017
                     /EC_number="2.7.7.65"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017081.4"
                     /locus_tag="HOP40_RS30495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30510"
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_172165583.1"
                     /transl_table=11
                     /translation="MTGPSPPRAAWPAAAWTRSPLVVGVAVLVLALGAVVLRPEGSGVA
                     AWWPAAGVAVAAAACTTGRRRGAVLIAVGAGILAANLLGGRPVALAVAFTAANVAEAAL
                     AARLLSADGHPELRTLPQLARLLGAAGAGALVAGTLSAAGVALLAAGDPWAAGSAAAAA
                     HGAAIVVLVPAVMHLPDRAAPPRRWEVAALWALVVAGTVVVFLPGQTMPLGFLVVAALA
                     GTGLRLGVRAASAQLVAVGVVVGVLSALGGGPFAAAGRAHGPAVTGTLEQLYLGSCAVV
                     VLALAISVAQREAALVQLARLRRFDLAVLEVVNAGVLACDADGNVLVRNRVHRRATGVD
                     RTVDDADGHVLATGIRVTQDGVALPPSRTPMQRALAGEVLTDESLRIEPASGPASDVVA
                     MAGPIHDHDGSLLGAVVAFADVTAERAVQARLRESLAFREAVLAVSPDTLFLFDPRSRE
                     TLWLSPSGTGSPEDSPTDLVALGGEPCQQRVHPADVARLVAADEAARGLADGAVLKLRL
                     RIRDWQGRYRWVSRRVTPFDRDEAGEVTALLGVARDITENVELEERLAAAALHDPLTGL
                     PNRRLLADRLETALHRASRTGSEVPVLFCDLDGFKVVNDTAGHAVGDALLQATAARLKK
                     VLRPQDTVARVGGDEFVAVLDPALRAVDPVDARAEVRRQARSVARRIVVALAEPFVVDG
                     VPHAITVSIGITFAVAGAEPEQALRDADRAMYQAKLLGKGRHQELDDVSGQA"
     gene            complement(22041..22814)
                     /locus_tag="HOP40_RS30500"
                     /old_locus_tag="HOP40_30515"
     CDS             complement(22041..22814)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005449564.1"
                     /locus_tag="HOP40_RS30500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30515"
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="WP_172165586.1"
                     /transl_table=11
                     /translation="MLYWWSKFVFLGPLLRLFCRPTIEGLEHIPARGGAILASNHLAVV
                     DSFVLPLVVPRRITFPAKSEYFTKPGLVGRMQKAFFTGVGQIPIDRSGGSAARDAMDTA
                     VRVLREGRLLGIYPEGTRSPDGRLYKGKTGVARMALEAGVPVIPVAMIGTDKVNPIGSR
                     MWRPRKVHIRVGEPLDFSRYAGMEGDRFIERSMTDEIMYALMELSGQTYVDMYAASVKE
                     RAAKALAEKAEPAAADGVGDVPRPAPPTVPDTRAS"
     gene            22972..23451
                     /locus_tag="HOP40_RS30505"
                     /old_locus_tag="HOP40_30520"
     CDS             22972..23451
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HOP40_RS30505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HOP40_30520"
                     /product="hypothetical protein"
                     /protein_id="WP_172165588.1"
                     /transl_table=11
                     /translation="MGGDPDERPHPDGWVDDFDAIVAGWRREGAVPEWPDEEPPAAVRE
                     PGSPDGPSSDLPPPTAPEPPPIVVRPGPRTAPEDDHFVPPEPPPIPRIGPPAAVGLVLL
                     VLGIVLVTAPGWVGVPDTYGLPLGLLTLAAGLGWLVLRLWPSPPGPGQDDDGAIL"
     gene            complement(23457..24884)
                     /locus_tag="HOP40_RS30510"
                     /old_locus_tag="HOP40_30525"
     CDS             complement(23457..24884)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="HOP40_RS30510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_30525"
                     /product="MFS transporter"
                     /protein_id="WP_172165591.1"
                     /transl_table=11
                     /translation="MDRTVSTTTGTPPGPPAGLRPGGTLAITAGGTLLSMTAFTAPFSI
                     IPTVARDLGAGPVGTSWVLSSMSLGLAVALLTSGAIGDEVGRRRVFVAGAALLAAGSAA
                     CALAPDAWTFVVGRVLEGIGSAAVIACGLALISHTFPGPDRARATGIWGACMGAGPAVG
                     PPLGAVLAAVADWRFAFVVVAVVSVLLAVAGQRLLTESRSGRGRRVDVTGALLLAVGTG
                     ALLAGLTEGRRGWTGPLALGLVAGAVVVLAVFLVHQRRAREPMLELALFRRPALVSATF
                     AAFVTGAAIIALMSFVAVVLESGLAYTSVQASVIGIGWSGFSVVFALLARRIPLRVPGA
                     ARLAAGLLTIALGLLPLALLDTGAPLAQVLVGLVVAGVGSGVVNATLAREAVASVPAAS
                     AGAGSGLNNSSRYIGAAFGVTVVTALAVHPDGTPASLVAGWNTAVLVGIVLSVVGAVVV
                     LLLQRAETRYLAAAAAV"
     misc_feature    24868..24883
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.14"
                     /tool="antismash"
ORIGIN
        1 aggcgatggg ctcgggcgag ggcaccccgg gcgccgcgct cgcccaccag gggcagggcc
       61 ggtccgacgt cctcgtccgc cagtaccgcc agggcgacga gctgcgccgg gtccactggc
      121 gcagcaccgc ccgccacgac gagctgatgg tgcggctcga ggagcgcccg tggcgcaccg
      181 gcaccaccgt gctgctcgac cgccgcgacg ccgcccaccg cgggcacggc cccgacgcca
      241 gcctggaggt cgcgatcagc ctcgcggcga gcatctgcac ccacctcggc ggccggggcg
      301 aggtgatcac gctggtcacc gaggacggcg ccgcgctggg ctccgcgtcc ggtgacgtcg
      361 acccgctgct cgacgccctc gccgccctgc gccccgccgc ccgcaccgac ctcgccgggc
      421 ccgagctctc cggcgacgtg ctggccgtgc tcggcgggat ggagtcgggg cagctggagg
      481 ccctggtcgc ccggcagccc gcgggcgggc acgccgtgct gctcgacgtc gccggctggg
      541 acccctccgg ccgcggcccg gacgccgccg ccaccgcggc cgccctgcgc tccgccggct
      601 ggcgggtggc cgtcgcccgt gccggcgtcg ggccggaccg cgcgtgggac gacctggtcg
      661 cgcagagcat cgggagcacc gcatgaccag gaccgcagca tgaccctcac cgcgccccgc
      721 cccctgcgcg ccgccccgcc tcccccgccc gcgccgcccg cccccgggcc ggtcgtgcgg
      781 ccgctcgccc ccctgctgtg cgcggtggcg gtgctgctcg ccgccgcgcc ggtctcgtcg
      841 gtcgtgcagg gctggacctg gctcggctac gcgggcggcg ccgtggcgct cgtcgcggtc
      901 gtcggcgtgg tcggggcgct ggtgccgcgg gtgcccgccg tcgccgtcgc gctggtgcag
      961 gtggcggccg tgctcggcct gctcaccgcc ctgttcaccg acgacggcgt ggcgcgcgtg
     1021 ctgcccgggc ccgccgcgct cggcgacatg ggcgcgctgc tcgcgggcgc gggcgcccag
     1081 atcgacgtcg gcaccgcacc cgtcgcggcc accccggaga tcctgttcct ggtcacggcc
     1141 gcgctcgggc tgctcgccgt ggcggtgcac ctggccgtcg tcggggcggg ggcgccggct
     1201 gcggccgggg tgccgctgct cgccgcgttc gccgtgcccg ccgcgctggc cgacgacctg
     1261 ctgccgtggt ggacgctcgc ggtcgccgcg ctcggcttcg gggtcctgct cctcgcgccc
     1321 gacggcaacc ggcgccagat ccccggcggc gcggtgctcg tcgcgggggc ggcggtggtc
     1381 gccctcctgc tcggcacggc cacggccttc gtcggcacgg cgggccggtt cgacggcggc
     1441 gaggacggca ccggccgcgg cgcgatcggg ctcagcccgt tcacggcgct gcgcggccag
     1501 ctcgaccaga gcgagcccac tcccctgttc gaggtccgcg gcctggcgca gccgcagtac
     1561 ctgcgcgccc tgaccctgag cgactaccag gccgggatcg gctggcaggc cacccggccc
     1621 gggccgggcg tcgcgccgga ggggccgttc acgcagcccg gcgtgcccgg cgacgtcgtc
     1681 gacgtcacgg tcggcaacgt cggcttccgc gactactggc tccccgtcta cggcgccccg
     1741 ctgggcatcg gcggcctcgc gcccgacctg ttcgtctacg acgagcccag cggcatcgcc
     1801 tacaccgccc gcccccagca gcaggagacg tggaccgagc gggcgttcct gcccgcgccc
     1861 accaccgacc tgctgcgcgc cgcgcagggc gagcgacccg ccgcgatcta cgcgaacatc
     1921 ctgggcgtcg acccgcgggt caccgagatc gcgcagcagg tcacggcggg tgcggccagc
     1981 gacttcgacc gcgcgatggc cctgcaggag tacttcaccg ggcccgacac cgcgttcacc
     2041 tacgacctgg cgacggcccc gcccgcgggc gacgacgcgc tcgtcgagtt cctcaccgtc
     2101 ggccgcgtcg gctactgcga gcagttcgcc tcggcgatgg cggtcatgct gcgcagcgtc
     2161 ggcgtgccgg cgcgggtggc ggtcggcttc accgcgggct ccccgatcag cgactaccgc
     2221 gccgtgagca cggccgacgc gcacgcctgg gtcgaggcgt ggttccccgg catcggctgg
     2281 acgacgttcg acccgacgcc gctcaccgac ggccgcacga tcacccctcc ctacgtcgag
     2341 gccgcgcgcg ccgaggccgc gggcgggggc accggcgccg gggccgtccc ggccgcgccg
     2401 accggggccg cgccgaccac cgcacccacc acggccccgg gcgagcagcc cctcgacgcg
     2461 gccgcacccg cgcccgtcgc cgccgatccc ggcctcccgc tgtggccgct gttcgtcgtg
     2521 ctgggcctgg tgctcgtcgg gctggtgccc gccgcggtgc gggcgctgcg cgggcggtcc
     2581 cgcctcgcgg ccgcggcggc gggcggcacc ggggccgcgg gggcggcctg ggacgagatc
     2641 gtggcgacgt cggtcgaccg gcgggtgccc gtgccggcca ccgacaccgt ccgcgcggcg
     2701 gcccggcggc tggtgcggga gcaccggctc gacgcggcgg cccaggacgc ggtgcgggcc
     2761 gtggtcggcg cggtcgaggc gagctggttc ggcgaccggc accccgagcc gggcgagctc
     2821 gccggcccgg tccgggtcgt gcgcgacggg atcgccgcgg gcagcccggt gtcgctgcgc
     2881 gggcggttgc tgccgcgctc ggtgctggtc cggccggtgc ggtcggcgcc cgaggcgccg
     2941 gtcacgacgt cggtctgagc cccgcccggt cttcccccag acacgacgca gcgcccggac
     3001 cgagggtcgg tccgggcgct gcggctgtcg gcgagagcgg ctagtcctgc tcgaaccggc
     3061 ggcggaagcg ctcttccatc cggccggtga agccgttctt ctccttctcg gcctcagccg
     3121 gcgtgccgga gcccgcgggc gccttgccgg acgaggtgac cgcgagcacc gagccgccga
     3181 gcatcacgac gaacccgagc acgctgagca cgatgagggc gatcatgccg ccgccgccgc
     3241 cggacaagga ctggatcacg acgccgacga cgagcatgac gagaccgagc aggaacaggg
     3301 cgacgccctg catgcgccgg cgacgggtcg gtttgcgcaa ccgaccgccg cgcacggtcg
     3361 aagcgaactt ggggtcctcg gcgtagagag cgcgctcgat ctgttcgagc aaccgctgct
     3421 cgtgctcgga gaggggcatt acatcgcctc cggcactgct tgtgctgttg tcggtcatct
     3481 tccatggtgc cggaacgacg cgacgaacgc ccgggctggg cctcctggaa cagaggatac
     3541 gaggccgcgg gccggtcgac cacccgcact cgtcgagcgg gtggttccgg ttcaccggcg
     3601 gcacgtccgg gcgaccccgt tcgagggacg gccgacacgc tgcgcaaccg ttcgaccacc
     3661 tggcgcagcc cactgcaccc ccaccgacct gggcggcggg ccgccgagga cgacctgcca
     3721 ccacgccggt gaccgtccgc caccccggtc gggggtgcgc gggatcaccc ggccgggagc
     3781 ggccgccgcg ccaggacgtg cagccgcgcc gcgagctcca gcagggccgg acgcgccgcg
     3841 gccagcacct cgagctcggc gacggcccgg gtggccgccg ggccgctgtc gcgcaccgag
     3901 ccgggcaccc agccgtcgag gacgccgtca ccctgcacca gttcgggcag cagaccggcc
     3961 gcgtcgagca gcgcgcgcag ctcggtggcg tcgaggcgcc ggcgcagcgg gtcgtcgggc
     4021 ccggagcggc cgtgggggtc ggtgagcagg gcccgcgcct cggcgaggcg cccggccagc
     4081 gtgcggccca gcaccgcggc gtggcgcccg gccacgagca ccgagaccgc gccgccgggg
     4141 gcggtcgcgt cggcgagggc gcccagcgcg tgcggcgcgt cgtcgacgac ctccagcagg
     4201 ccgtgtccga gcaccaggtc ggcgccaccg gcgggcgcga cgtcggcgag ggcgtcgacg
     4261 tcgcactgga cgggcgtgac ccgcccgtgc accccggcgt cccgggcgcg gcggtgcagc
     4321 gcggcgagcg cgttggggct gttgtcgacg acggtgacga cgcagcccag ccgcgccagc
     4381 gccaccgccc acgccccgct gcccccgccg acgtcgagca cgcgcggttc ggcgccgcgc
     4441 gaccgggccc gttcggcggc ccgcgcgacc tccgcctcca gcgcgcggtg cacgggaccg
     4501 ggcggcaccg tgcccgtcgg gtcgggtccc gcgttgctcc cggcaggtgc gttcacgacg
     4561 acagcctcac ggcagcagcg tagtgggcgc cccggacggg taggttgatc gccgtgcagg
     4621 tcgtcgccac gttgagcctc aagggtggag tgggcaagac cacggtcgcc ctcgggctgg
     4681 ccggggcggc ccagcagcac ggtgtccgca ccctgctggt cgacctcgac ccccaggcca
     4741 acgccaccat cgccctcgac gtgggcgaca cctccgccac cgtcgccgac gtcctcgacg
     4801 acccgcgccg ctccgtgctc cgccgcgcca tcgcccccag cggctggggc gagggcctcg
     4861 acgtgatggt cggcgccgag cagaccgagc gccacaacca ccccgacccg ggcgcgaagc
     4921 agctcagccg cctcacccgc gccctgggcc ggctcgtcga cgccgacgag gaggacgccc
     4981 gggacggtgg cgccgaggag cacgacctcg ggccgtaccg gctcgtcgtg atcgactgcc
     5041 cgccgtcgct gggccagctc acccgcagcg ccctggccgc cgcccaccgc gcggtgctgg
     5101 tgaccgaccc cacgatgttc gccgtgtccg gcgtccagcg cgccttcgac gccgtgcaga
     5161 ccgagcgcca gcgcggcaac cccgacctgc agcccctcgg cgtcctcatc aaccgcgtcc
     5221 gcccccgcaa cgccgagcac gagttccggg tggcggagct gcgcgagctg ttcggacccc
     5281 tggtgttcag cggcgtcctg cccgaccggt cggccgtgca gcaggcccag ggcgcctgcg
     5341 tcccgatcca gagctgggac acccccggcg cccgcgaggt ctccgcggtc ttcaccaccc
     5401 tgctgggccg ggtgctgcgg agcgagcggc ggccgcgggc ggcgacggct ccgcctccca
     5461 ctcgctgacg gctccgcgcc cccgccgtac gaccttgatc accgcgacag caccggcagg
     5521 gtcgtcgcga ggaccgcagc gtcacactcc tgacgatcac ggttcggcga tcgccggaac
     5581 cgcaccacca gcgtcgccgc gacgaccgtg ccgtcgcact cccgacgatc acccgcccgc
     5641 atgcctcccg ccgggcgccg cctcgccatc agcccttgat cgccgagacc gcaccgccgg
     5701 cgtcgttgca aggaccgcag cgtcacactc ccgacgatca ccggctcggg accgtctgga
     5761 ccgcacgacc acggtccctg cgacgaccgt ggcgtcgcac tcccgacgat catccgggcg
     5821 cacgcctccc ggcgggcgcg gcctcaccac cagcccttga tcgccgggac cgcaccgcca
     5881 gcgtccccgc aacgaccgtg gcgtcgcact cccgacgatc acccgggcgc acgcctcccg
     5941 gcgggcgcgg cctcaccacc agcccttgat cgccgcgtcc gcaccaccag cgtccccaca
     6001 acgaccgtgg cgtcgcactc ccgacgatca cgatcccgct ccggccgctg atcgcgagga
     6061 cgccaggccg acgccccacg gcgacacacc cgcggaacgt ccgggcggcg gcggccaccg
     6121 tggccaccgt ggccaccctc ccgcgcgctt tcccggctgc cgcgcggatt tcccgctccc
     6181 gcgcgccccc ggggccgcgc gggagcatgt tcagcgcgcg ggagccgtct cggcgcgcgg
     6241 gagcgggggc cgtgaccccc ctcgcgcacg atgagacatc gccgccgtgc tccaccagcg
     6301 tcgccgcgag gaccgcagcg tcacgctccc acgatcaccc gaccgcacgc ctcccggcgg
     6361 gcgcggcctc gccatctgcc cttgatcgcc gagaccgcac caccagcgcc cccgcaacga
     6421 ccgtgacgag accatcccga cgatcactcg ctcaagatcg ccggaaccgc accaccaccg
     6481 cccccacgac gaccgtgacg ccacactccc gacgatcacc gccaaccccg caccgccacc
     6541 gccccggcca cgagcagcga cgacgtcgcc cggactgggg caggcgcctc accgcaaccg
     6601 caccgactcc gtcaccatcc ccacgaactg ctcggcctgc ctcagcaggt cgtcggcccc
     6661 gcgctggtcg accaggcggg cgatgcccgc ctcggccgcg gcccgggtgg cggagcagga
     6721 ggcgaagaac gccgcccact cccccagctc gggcgccacg gtggcgagga tgtcccacac
     6781 cgcgcggggc gcgccgcggc ggggctgagg ggcggcgcga acggccagga ccgccgcccc
     6841 ggcgcgcagc gcggccaggt aggcggccgg gtagcgccgg agcgggtcgt gctcgcggtg
     6901 ggcctcggcg agcccgtcgg cggcctgccg cagcagcgcc agcgccgaac gggagaccgg
     6961 ggccgggcgc ggcgcgggca ccggtcggtc cgtcgtgatc gtcatcggac acctccctgt
     7021 tcctgcacga acacctgttc ggacaacccg cgccgacctg cggtcattcc gggacccgga
     7081 cgagatccca gacaccgggg cccgcgcgca tccgcagcac gaactcgcgg ccggggacgt
     7141 cgggctcgtc ggccgagcgg gcctcgaccc gccagcaccg caggcggtcg cccccgacgg
     7201 gcatgggtga ggggaacggc cacggcgact gctcgatcca ccgctcgcgg acgtcgacga
     7261 tcaggtagcg cggcccccgc cgcgcgggcc tgcgctggaa ctcgacgggc tccccgtcca
     7321 gccagcgcac ctggacgggt gtgggctccc gggaacggaa cacccggctg aaggcactca
     7381 cgctgcactc ctcccgaccg gcctgttccg accggcaccg tgcccggccg gtctgggttc
     7441 cggccggtcc ggtcggcccg gcggccgggt gcttccccca ccccgccgcc ggacccaccg
     7501 atgatcgaac gcatgttcga tcccctccag tacaacctcc cgccgccccc gcgtcaagtc
     7561 gcgcaggcgc ggcaggacgg gacgccgccg acgtggtgtg atggcgcggt gaccaccgca
     7621 ccggcccggc acatcgtgga gtggggcccg tccgacctcg ccgcgcgcgt cgacgacgcg
     7681 ctggccgtgt acgtcgccgc gatgggctac ccgccgagca ccgcgcggca ccgccgcacg
     7741 ctgtggctcg accacgtccg ccgcccgggc tggcgcgccg tcggctgcgt cgacgacgcg
     7801 ggccgactgc tcggcgtcgc ctacggctac acgggggcgc ccgggcagtg gtggttcgag
     7861 gaggtctccc ggggcctgcg cccccgcccg caggagcggt tctggctcga ggactacttc
     7921 gagctcaccg agctccacgt gcaccccgac acccagggcg gcgggctcgg cgaggggctg
     7981 ctccgcacgc tgctcgcggg cgcgaccgcc cggcgggtgc tgctctcgac gccggagaac
     8041 ggcgacggcc ccaccaaccg ggcgtggctg ctctaccgcc gcctgggctt cgccgacgtc
     8101 ctgcgccacc accgcttcac cggcgacgcc cggccgttcg ccgtgctggg ccgcgacctc
     8161 ccgctgccgc ccgcgccccc gaggtgacgc ccggccgcgg atggcacgat ggcgtgatgc
     8221 cgtccccgcg ccgccggccc gcgctgctgc tcgtcctggt cctcgcgctg ctggccctgt
     8281 ccggctgcgc gcgcgtgcag gccgcactgg cggtgcagcc cgacgacacg gtgcgcggcc
     8341 agatcgtcgt cgccacgccc gagacgggcc ccgaggaccc gggaccggtg ctgacgctcc
     8401 cgcccgacct cgcggcgtcg gtggacgtca gcgagtaccg ccaggagggc tacgccggct
     8461 cgctcgtgcg gttctccgac ctcaccttcg agcaggtcag cgagctgatc acggccgcgg
     8521 ggccgcccgg ggagaaggtg cgcctcgagc tgcgccgggc gggcaaccgc gtggtcgtca
     8581 acgggtcggt cgacctcacc accgtcgacg tcgaccgctc cgacttccag ctcaagatcg
     8641 ccttccccgg ccaggtcctc gacgccaacg gcgacgccga ctccggcgag gtcagctggg
     8701 tgttcgaggc gggcgaggtc ggcgacatcg aggccgtcgt ggccttcgac gacccggacg
     8761 cgccctcgcc gttcaactgg agcctcggcc tgttcctggt ggtggcgctg gccgcggccg
     8821 cggtggtgct ggcggcgcac cgcacccgca acccgccggt ccggcagggc tgagtcggtc
     8881 cggcagggct gagtcggtcc ggcagggctg agtcggtccg gcagggccga gccggtccgg
     8941 cagggctgag ccggtccgcc ggggccgggt cggcctctca ggccaccgcc actccccgcc
     9001 gcgcccccag gcccagccgc tgcacgagct cggtcgtggc cgtggagcgg ttgaacgtgt
     9061 agaagtgcag cccgccgacg ccctcggcga gcagccgcgc gcacagctcg gtcgtgaggt
     9121 ccatgcccgc ccggcggaac gcggccgggt cgccggcgta gcgctccagc cgctcggcga
     9181 gcccgggcgg cagcggcgcg ccggacagct ccgggccgcg gtgcagcgtg cgcagcgtcg
     9241 tcagcggcat gatcccgggc agcagcggga cctcgcagcc ggcggcggag agccggtcgc
     9301 gcagccgtag gaatccctcg ggctccagga acagctgggt gatcgcgaag tcggcgcccg
     9361 cccggacctt ggcgacgagc cgctgcaggt cggagtcctc gtcggccgag cgcgggtggc
     9421 cgtaggggaa ggcggccacg ccgacgcaga agtcgcccag gctgcgcacc agcgagacga
     9481 gctcgtcggc gtacatgagg ccctcggggt gggcgaccca ctcgcccagc gggtcgccgg
     9541 gggggtcgcc gcgcaccgcg aggacgttgc ggatgcccgc cgccgcgtac tcgccgatga
     9601 cgtggcgcag ctcggccacc gagtgcgaga cggcggtgag gtgcgccatg gcgacgagcg
     9661 tggtctccga cgcgatgcgg ccggtggtgc gcacggtccg gtcgcggctg gacccgcccg
     9721 cgccgtaggt gaccgaggcg aacgccgggt cgagcggctc cagcctgcgg atggcgttcc
     9781 agagctcggc ctcgcccgcg tcgtccttgg gcggcatgaa ctccaccgag aacaccggct
     9841 ggtcgccgcc gatccggtcc gtgatcttca tcggatggtc tcctcggatg tggtccgtgc
     9901 gggaggagcc tagtgggccc cgccgccacc gcgccgacgt ccggcaccgc cgctaccctc
     9961 gtcaggtgcc tccccgatcg tcacgccgcc tggcgtcctc gtgacccgca ccgccccgga
    10021 gcgcgtccgg gccgccgacg acgagctgtc cgacgccgtg gaggaggtgc tggcggccta
    10081 cctggagcgc cggggcgccg acacggccgc catcgacccc gcgttcgggg ccgccaccgc
    10141 ggcgctgacg gagttcgtgc tgagcggggg caagcggctg cggccgacgt tcgcctggtg
    10201 ggggtggcgc ggcgcggggg gctcccccga cgacgcgcac gccgtcggcg tgctggaggc
    10261 gatcagcgcc ctggagctga tccaggcgtg cgcgctcgtg cacgacgacc tgatggacgc
    10321 ctcggccacc cgccgcggcc gccccaccgt gcacgtcgac ttcgcccggc gccacgccga
    10381 ggccggctgg cagggccgcc cggcgcgctt cggcgcggcc gctgcgatcc tgctcggtga
    10441 cctggccctc gtctgggccg acgacctgtt ccgctcctcc gcgctgccgg tcgaggcgct
    10501 ccgccgcgcc gcggcgccgt gggaggccat gcgcaccgag gtcctcggcg ggcagtacct
    10561 cgacgtgctg caccagtcca ccggcgacac gagcccgcgg gccgcgctgc aggtcgaccg
    10621 ctacaagacc gccgcgtaca ccgtcgagcg cccgctgcac ctgggcgccg cgatcgccga
    10681 cgcgtccccc gagctggtcg cctgctaccg ccgcttcggc gccgacatcg gcatcgcctt
    10741 ccagctgcgc gacgacctgc tcggcgtctt cggcgacccg gccgtcaccg gcaagcctgc
    10801 gggcgacgac ctgcgcgagg gcaagcggac gctgctgctc gcgctggcgc tggagcgcgc
    10861 cgccgagcag ggctcccggg cgtcggcggc ggcgatcgag gccgcgctcg gcgaccccga
    10921 cctcgacgcc gacggggtcg accgcgtccg cgggctgctc gtcgacctcg gcgccgagca
    10981 ggctgtggag cagcgcatcg cggcgatgac cggctccgcg ctcgacgccc tgagcaccgc
    11041 cgacatcgag gagcccgcgg cctcgcggct ctccgacctc gccgtcgcgg ccacccggcg
    11101 gcggcgatga ggctgcgcac cgtcaccggt cccaccgacc acgtcgtcgt ggtcggggcg
    11161 gggttcgccg gcctcaccac cgccctgcac ctgctgggcg cgggccgccg cgtcacggtc
    11221 gtcgagcggg gcgagcaccc cggcgggcgc gccgggcgcc tcgacctgca gaccgcctcg
    11281 ggcacctacc aggtcgacac cggccccacc gtcctgacca tgcccgacct gctcgacgag
    11341 gcgttcggcg ccgtcgggga gaaggtgtcg gagcggctcg acctcgtcga gctcgacccg
    11401 gcctaccgca cccacttcgc cgacggctcg acgatcgacg tccacaccga cgccggggcg
    11461 atggaggccg aggtccgcgc ggtctgcgga cccgacgcgg cggcgggcta cgtccgcatg
    11521 cgcgagtggc tcggcaagct ctaccgcgcc gagatcgaca cgttcatcgg cgccaacttc
    11581 gactcgccgc tgaacctgct cggccccgac ctggtgcgcc tggccgcgct cggcgggttc
    11641 gggcgcctgg gtccgcgggt cgagggcttc ctgcccgacg agcggctcca acggatcttc
    11701 tcgttccagg cgctctacgc gggcgtgccg ccgcagacgg cgctcggcgc gtacggcgtg
    11761 atcgcctaca tggacaccat cgccggcgtc cacttcccca agggcggcat gcgctcggtc
    11821 gggcaggccc tggccgacgc ggccgtggcc gccggcgcgg agatcctcta cgggcggacc
    11881 gtcaccggcc tggagcgcgg cgcgggccgc gtcaccgccg tgcgccaccg ggccaccgac
    11941 gacccgctcg gcgcgtccga ccggctcgcg gccgactcgt tcgtgctgac gccggacctg
    12001 cccgtcgtgc acgacctgct gggccgcgcg ccgcggcgcg tcgtgcctct gcgctactcc
    12061 cccagcgccg tcgtcctgca cgccgggctg cgcacctccc gaccggaggc ggcgcaccac
    12121 accatctcct tcgggtcggc ctggcgggag acgttccgcg agatcatcga cgacggccgc
    12181 ctgatgagtg atccgtcact gctgatcacg cgcccgacgg ccaccgaccc ctcgctcgcc
    12241 cccgacggcc gcgacctgct gttcgtgctc gccccgtgcc ccaacctcga ggcgggcccg
    12301 atcgactggg agcgcgtcgg accggcctac cgcgacgagc tcctcggcgt gctggaggcc
    12361 cgccagcacc cggggctcga cggcatcgag ggcgacatcg aggtgtcgga cctggtcacc
    12421 ccggccgact gggccgcgca ggggatggcc gcgggcaccc cgttctcggc ggcgcacacg
    12481 ttcgcgcaga ccggcccgtt ccggccgcgc aacctggtcc gcgggttcga gaacgtggtc
    12541 ctcgcgggct gcggcacgac gcccggggtc ggcatcccgc cggtgctgct gtcgggccgc
    12601 ctggccgccg cgcgcatcac cgggcccgct ccgacgaccg ggcggggtcg cagggtcccg
    12661 acaggcggct gagggcggcc atggcagcat ggtccgcgcc atgaccgcgc agccctcctc
    12721 ccccgtcgac cggtcggagt cacccgatcg ggccgtgacg gcgcccgccg gcagcacgcc
    12781 ccgggcgtcc gcgtggcgtg cccgcctggg gtcgcctccc cggggtccgc tggtgctcgg
    12841 cgtggtcgcg tcgctgctca tggtgctggg cgggttcggc gcgggcggcg tcctcgtcga
    12901 cgacccgctg ctgacgaact cgccgctggg cttctggcgc tacggccacg gccgggagat
    12961 cgccaactcg ctgatctacc tcggcgtcgg gctgctggcc tgggcctggg tccggctggg
    13021 ccgcgaggtg ctggcgcggc gcgtcggcgg ccgcgcggtg ctcaccaccg ccacggcgtg
    13081 gctgctgccg atgctggtgg cgcccccgct gttcacccgc gacgtgttca gctacctcgc
    13141 ccagggcgcg ctgccgctgc acgggttcga cccgtacgcc gtcgggcccg acgcgctgcc
    13201 cgggatcttc accgacaacg tccactactt ctggcaggac accccggcgc cctacggccc
    13261 gttgttcatc ctctacgcca agtcggtcgc gtggctcgcg ggcgaccaga tcatcctcgg
    13321 cgtcgtgctc atgcgcctcg cgctcgccgt ggggctggtg ctgctggtcc gggccctgcc
    13381 cgagctgtcg cggcggatgg gcgggcggcc ggcgctcgcg ctctggatcg tcgtcgccaa
    13441 ccccgtcatg gtcatccaca tggtcggcgg cggccacaac gacctgctgg tcatgggcct
    13501 gctggccacg gccgcgctgt cggcgctgcg cgggcagcac gcctggggca tcgtgctcgc
    13561 cacgctcgcg atggcggtca aggccagcgc gggcgtcgcg ctgccgttcc tggtactggt
    13621 ctgggcgggc acgatggccg gctcggtgct cgcgcgcacg ctgcgcgcca ccgcgtacgg
    13681 gatcgcggtc ttcgtgccgg tgttcgcgct gtgcacggtc gcggccggcg tcggactggg
    13741 ctggctgccc gcgctcagcg cgccgtcgat gatcgtcaac tggatgtccc tgcccaccgg
    13801 cgcgggccag ctcgtgcact cggtcgtcag catcttcgga cccgtgtcga tgcagccgtt
    13861 cgtcaacgcg ggccgtgccg tcggcgcgct gatcctgctg gtgatcgccg tgcaccagtg
    13921 gtgggcctcg cgcgacggcg gccccgacgc gatgcgccgc gccggcatcg tgctgctggc
    13981 cgtcgcgctg ctctccccca ccacgctgcc ctggtacgtc agctggggca tggcgctgct
    14041 cgcgatggtc gactggacgc cgcgcgcgct gcaggtgctg gtcttcttct cgctctggct
    14101 gatgatcgtc tactaccccg acggcgaggc cgcgctctac gacctggcgg tcctgggcat
    14161 cggcgccgcg ctgtcggcgc tggccgcggt gtcgctgctg cggcccgacc cgctcgggct
    14221 cgcccggcgc ccggtgggag ccgacccggt tgtccggtag cgccgagctc gacgccgcgg
    14281 gcatcaccga cccggccctg cgcgccgcct acgccacctg ccgccggctc aacgcggccc
    14341 acgggcgcac gtacttcctc gccacccgcc tgctcccgcc cgaccgccgc ccggccgtgc
    14401 acgccctcta cggcttcgcg cgctatgccg acgagatcgt cgacgacctg ggcgacgacc
    14461 ggcccgtcgc cgagaaggcc gcggagctcg acgccctcac cgcgggcctc cacgccgcct
    14521 tggacggcgc gcccaccgac gtaccggtcc tcgcggcgct gggcgacacc gcccgccgct
    14581 acggcatcga ccgggcccac ttcaccgact tcatgacgtc gatgcggatg gacacccacg
    14641 tcacgtccta cgccaccgac gccgacctcg ccgtctacgt ccacggctcg gccgccgtga
    14701 tcgggctgca gatgctgccg gtgctcggca cgacggtgcc cctggaggag gcgacgccgc
    14761 ccgccacggc gctcggggtg gcgttccagc tcaccaactt cctgcgcgac gtcggcgagg
    14821 acctcgaccg cggccgcgtg tacctgcccg ccgacgagct cgccgcgttc ggcgtcgacc
    14881 gcgagctgct ggcctggtgc cgcgcgcacc gccgtgccga cccgcgggtg cggcgcgcgc
    14941 tcgcgcacct cgtcgcccgc acccgcggca cctaccgccg cgcggcgccc ggcatcgcca
    15001 tgctggagcc ggtctcccgg gcctgcgtcg gctgcgcctt cgccctctac cagggcatcc
    15061 tcgacgagat cgaggccgcg ggctacgccg tgctgcaccg ccgggtggcg gtgccgaacc
    15121 gcaggcgcct cggcgtggcg ctcccgggcc tggcccgcgc ggtggcggcg aggaggccgg
    15181 gagagcgccc cgctagaacg ccatcgcctg cgcgcggcgc ttgatctccc ggtggcgccc
    15241 ctcggtgagg aacgacatcg gggagccggg cagcgagtcg tcgacggaga acagccagcg
    15301 caggatgtcc tcgtcgctgt agccgccgtc gcgcagcacg gtgatcgtgc ccggcaggcc
    15361 cttcacgacc tccgcgcgct cctcgccggg cgagaagaac gcagcgggca ccaccacctc
    15421 gccgtcgcgg cgcagggaca ggatctgccc gtcgcgcacg agctggtgga cccgggacac
    15481 gggctggttc aacagggttg cgacctcggc gacgggcagc gtctccacgt cgtcggccag
    15541 aacggacacc tcactcacga ggcgacagga tgccacatcc ggtgccgtcc ccgcgcctgc
    15601 tccgggccgc cggtggccgg gcggtaccgt caggctcgtg aacgccccgc ccgccgcgct
    15661 gctcgacgcg cgctaccggc tcggtccggt gatcgcccgc gggggcatgt ccatcgtcta
    15721 ccggggcacc gacacccgcc tcgaccggcc cgtcgcgatc aaggtgatgg agccgcggct
    15781 cgcggccgac ccggcgttcc gcacccgctt cgagcgggag gcgcgctccg cggcccggat
    15841 cgaccacccg gccgtcgtcg acgtctacga ccagggccgc cacgtcgacg acagcggcgg
    15901 ccacggcccg gagcccgtgc tgttcctcgt gatggagctc gtggagggcg ccaccctgcg
    15961 cgacgtcctg cggatgcgcg ggcagctggg cgtgccgggc gcggtggccg tgctcgaccg
    16021 cgtgctcgcc gggctcgccg aggcccaccg gctcgggctg gtgcaccgcg acgtcaagcc
    16081 ggagaacgtg ctcatcagcc acaccggcga ggtcaaggtc gccgacttcg ggctcgtcgt
    16141 cgcggcggcg caggccgggg ccagccacgt cggcacgatc atggggacgg tcgcgtacct
    16201 gtcccccgag caggtcgcca ccggctccgc cgacgcccgc agcgacgtct acgccgccgg
    16261 gatcctgctc tacgagctcc tcaccggcac gccgccgttc accggcgaca cggcgatctc
    16321 ggtggccttc cggcacgtca acgaccgcgt gccgccgcca tcgctgatcg cgggcgacgt
    16381 cccgcccgag ctcgacgccc tggtgctgcg ggccaccgac cgcgaccccg ccgcccgccc
    16441 cgccgacgcc ggggccctgc tgggcgagct gcgccgcgtc gcgcaccgcc tcgaggtgcc
    16501 gcgggtgccc gtgccggccc cgccgcggcc cgcgcagcac gcgaccgagc ccgtgacgca
    16561 ccccgggccg gtcgtgatgc ccgggccgcg cggcacgcag gcgctgcccg cgggcccgcc
    16621 gcgcggcgcc accagcaccg acctggccgg gccaccggcc ggcggcaccc tgcacggcgg
    16681 ggcgggcgac ccgttccccg accaccgccg cgcccggcgc cgcagccgcc gcgccttcgc
    16741 cgtcggcatc gcgctggtgc tcgtcctcgc gctcgtggtg ggcgcggtgg cctggtggat
    16801 gggcagcggg cgctggacgc aggtgcccgc gctcgtgggg gtgcagcaga ccgcggccgc
    16861 ggagctcctc gacgactacg gcctcgtcac cgggccggcc acgaccacgt tcgacaacgc
    16921 cgcacccgcc ggcgccgtgc tggccgtcga cccgccggtc ggcgcgcagc tgctgcgtgg
    16981 ggagatcgtc acgctgacgg tgtccaccgg gcgccccgtc gtgccgcccg tggaggccgg
    17041 caccgacgtc gccggcgccg agcagctcgt ccgcgacgcc gggctgacgc ccacccggga
    17101 cagctccgac gccgagttca gcgactccgt gcccgagggc gcggtgatcc gcaccgagcc
    17161 cccggcgggt caggccgtcg acatcggcgg ggcggtgacg ctggtcgtca gccgcggggt
    17221 cgagccgccg cccgcgcccg cgcgcgtgtc ggttccgatg gtcgtggggc agacggcctc
    17281 ggccgcccag gccctgctcg acgagctggg cctgagcacc gtggtgcagt cgacgctgcc
    17341 gttcgcgctc aacgaggacc cgaccgtgat cggccagagc cccgcggcgg ggacggtggt
    17401 cgaggagggc acccaggtcg tcctggacac cctctagacc ccgcggaccg tcagccgcgc
    17461 agcatctccg ccacgaggaa cgccagctcg agcgactgct gggtgttgag ccgcgggtcg
    17521 cacgcggtct cgtagcggcc gccgaggtcg gcgtcggaga tctcctgggc gccgcccagg
    17581 cactccgtga cgtcctcgcc ggtgacctcg acgtggatgc cgcccgggtg cgtgcccagg
    17641 ccgcggtgga cctcgaagaa gccctgcacc tcgtcgacga tgcggtcgaa gtggcgcgtc
    17701 ttgtagcccg acgtggactc gacggtgttg ccgtgcatcg ggtcgcactg ccagatgacc
    17761 ttgtgcccgg acgcctcgac cttctcgacg atcgcgggca gcacgtcgcg gaccttgccg
    17821 ttgcccatcc ggctgatcag cgtgagccgg ccgggggcgc ccttcgggtc gagccgctcg
    17881 acgtactcga cggccagctc gggcgtggtc gtcgggccga tcttgagccc gatcgggttg
    17941 gacagcagct ccgcgacggc gatgtgggcg ccgtcgagct ggcgggtgcg ctcgccgatc
    18001 cacaggaagt gcgccgacag gtcgtagagc cgggcctcct cgcgggtggt gtccatccgc
    18061 agcatcgcgc gctcgtagtc gagcagcagc gcctcgtgcg aggcgtagaa ctcgacgctg
    18121 tgcaggttgt ggtcgtcgac cccgcacgcg tccatgaacc tgacggcccg ctcgatctcg
    18181 gcggcgacgg cctcgtaccg ctcgcccgcg gcggacgtgc ggacgaagtc cttgttccag
    18241 tcgtggaccg tcgtcaggtc ggccatgccg gtggcggtga gcgcgcgcac caggttcatg
    18301 gcggcgctcg cgttggcgta ggcgcggacc atgcgggagg ggtcggcgcg gcgcgcctcg
    18361 gggtcggcga cgatcgagtg cacgatgtcg ccgcggtagg agggcaggcc cagggcgtcg
    18421 acgggcgagc tgcgcggctt cgcgtactgc ccggcgatcc ggccgacctt gacgacgggc
    18481 gtcgaggcgc cgtaggtgag gacgatcgcc atctgcagca gcgtgcggat ggtggcgcgg
    18541 atgtgcggct cggtgttgtc gacgaaggtc tcggcgcagt cgccgccctg cagcaggaac
    18601 gccttcccgt tcgcgacgtc ggccagccgg gactgcaggc ggtcgacctc gggcggcagc
    18661 gtcaccggcg gcacgctctc cagcaccgtg cggacgtgcg ccacctcggc cgcgtcgggc
    18721 cagtcgggct gctgcgcggc ggggcgggag agggcgtcgt cgagcctgct gcgcaggtcg
    18781 gcgggcagcg ggggcagctc gggaagcact tcgaccgggg cgtcgacggt ccagttcacg
    18841 acctcagcct agaaggtccc gggcgggggc cggtgcccgg tacgtcaccc gaacggcccg
    18901 attccactga ggacgatccg gatacctgac ctcatggcaa ccatcctctg gatcctggca
    18961 gtcgtcctcg tcgtcgccgg cgtcctggcg atcatccgca agcagctcgt gtggggcatc
    19021 gtgctgatcg tcgtcgggct gctcgtcggc cccggcggcg tcagcatctt cacctgaccg
    19081 ctcacgccct gaccccgtga cccctcccgg tcaggaccgg gcggccaccg ccgactcgat
    19141 cgcctcccac cgacgcaggt tcaaccgcgc gtcggccagg gcgtcgtgcg cgtcggcggt
    19201 gggcgggggc agggccgggc ggcccgcgtc ctcccagcgc tggcgcagct cgcgggtgaa
    19261 ccgcggcagc gcccgcggga gggcgggcat cgccccccac agctggcaca gcgccacgtg
    19321 gtcgtacgcc gcgatccacg cccacatctc cacgtccccg ccgggctcgg tgacgaagtc
    19381 gagcaggtcg gcgcgcaggc gcgaccggga ccgccacgcg gggtcggcgg gcgagggcag
    19441 cttgggcagc acgttggccc gcacccacgc ccccgcgcgc gacgggtcga actcggtgga
    19501 gaccgcgtag aactcgcgtc cgtcctcccc gaccaccccg atggacacca ggtcgatcgt
    19561 ggtgccgtcc tcgatgaact cgcagtcgta gaagaagcgc acgtcacgag gttagccgcc
    19621 gggtccggcg ggccgcccgg gcggccggtc cccgccaccc cgggcgacgc gtcgctaacg
    19681 ggatcgggca ggctccgata ccactggtgg agcaccgtgc ccgcacgttc ccggaaggcc
    19741 tcggccgggc ggtgccgtag ggacctcggg ggacccatga ccggaccgtc gccgccgcgt
    19801 gccgcctggc cggccgccgc gtggacccgc tcccccctcg tcgtgggcgt cgccgtgctg
    19861 gtgctcgccc tgggcgccgt ggtgctgcgc cccgagggct ccggggtggc ggcgtggtgg
    19921 cccgcggcgg gcgtcgccgt cgcggcggcg gcctgcacga ccggccgccg gcgcggggcg
    19981 gtgctgatcg ccgtgggcgc cgggatcctc gcggccaacc tcctcggggg ccggccggtc
    20041 gccctcgccg tggccttcac cgccgccaac gtggccgagg cggccctggc cgcgcgcctg
    20101 ctgtccgccg acggccaccc ggagctgcgc acgctgccgc agctggcgcg cctgctcggc
    20161 gccgcgggcg ccggagcgct ggtcgccggg accctcagcg ccgcgggcgt ggcgctgctg
    20221 gccgccgggg acccctgggc ggcggggtcg gcggccgcgg ccgcgcacgg cgccgcgatc
    20281 gtcgtgctgg tgccggcggt gatgcacctg cccgatcgcg ccgctccccc gcgccggtgg
    20341 gaggtcgcgg cgctgtgggc gctggtcgtc gccgggaccg tggtggtgtt cctgcccggg
    20401 cagacgatgc cgctcgggtt cctcgtcgtc gccgcgctcg ccggcaccgg gctgcgcctg
    20461 ggcgtgcggg ccgcgtcggc ccagctggtg gccgtcggcg tggtcgtcgg ggtgctcagc
    20521 gcgctgggcg gcggcccgtt cgccgccgcg gggcgggcgc acgggccggc cgtcaccggc
    20581 accctggagc agctctacct cgggtcgtgc gcggtcgtcg tgctggcgct ggcgatctcg
    20641 gtggcccagc gggaggccgc gctggtgcag ctcgcccggc tgcgccggtt cgacctggcc
    20701 gtcctcgagg tcgtcaacgc cggggtgctc gcctgcgacg ccgacggcaa cgtcctggtg
    20761 cgcaaccgcg tgcaccggcg cgccacgggc gtagaccgga ccgtcgacga cgccgacggg
    20821 cacgtgctcg ccaccggcat ccgggtcacg caggacgggg tcgcgctgcc gccctcgcgc
    20881 accccgatgc agcgggcgct ggccggggag gtgctcaccg acgagtcgct gcggatcgag
    20941 cccgcgtccg ggccggcctc cgacgtcgtc gcgatggccg ggccgatcca cgaccacgac
    21001 ggttcgctgc tcggcgccgt cgtcgcgttc gccgacgtca ccgcggagcg cgccgtgcag
    21061 gcccggctgc gggagagcct ggcgttccgc gaggccgtgc tggccgtcag cccggacacg
    21121 ctgttcctgt tcgacccgcg cagccgcgag acgctgtggc tgtccccgtc gggcaccggg
    21181 tcgccggagg actcccccac ggacctcgtc gcgctcggcg gcgagccgtg ccagcagcgg
    21241 gtgcaccccg cggacgtcgc ccgcctggtc gccgccgacg aggccgcgcg cggcctcgcc
    21301 gacggggccg tgctcaagct gcgcctgcgc atccgcgact ggcagggccg ctaccgctgg
    21361 gtgtcccggc gcgtcacgcc gttcgaccgc gacgaggcgg gtgaggtcac ggcgctgctg
    21421 ggcgtcgccc gcgacatcac cgagaacgtc gagctcgagg agcgcctcgc cgcggcggcc
    21481 ctgcacgacc cgctcaccgg gctgcccaac cgccgcctgc tcgccgaccg gctggagacc
    21541 gccctgcacc gggcgtcgcg caccggcagc gaggtgccgg tgctgttctg cgacctcgac
    21601 ggcttcaagg tcgtcaacga caccgcgggc cacgccgtcg gcgacgccct gctgcaggcc
    21661 accgccgccc gcctcaagaa ggtcctgcgg ccgcaggaca ccgtcgcgcg cgtcggcggc
    21721 gacgagttcg tggccgtgct cgacccggcg ctgcgggccg tcgacccggt cgacgcccgc
    21781 gccgaggtgc gccgccaggc ccggtcggtg gcgcggcgga tcgtcgtggc gctggccgag
    21841 ccgttcgtcg tcgacggggt gccgcacgcg atcacggtga gcatcggcat cacgttcgcc
    21901 gtggccggag ccgagcccga gcaggccctg cgcgacgccg accgcgcgat gtaccaggcc
    21961 aagctgctcg gcaagggccg ccaccaggag ctcgacgacg tctccgggca ggcctgaggc
    22021 caccgcccgg ggcgccgccg tcaggaggcg cgggtgtcgg gcaccgtcgg cggggcgggg
    22081 cgcgggacgt cgccgacgcc gtcggccgcg gccggctccg ccttctcggc cagcgccttc
    22141 gccgcgcgct ccttcaccga ggccgcgtac atgtcgacgt aggtctgccc ggacagctcc
    22201 atgagcgcgt acatgatctc gtcggtcatc gagcgctcga tgaaccggtc gccctccatg
    22261 ccggcgtagc ggctgaagtc gaggggctcg cccacgcgga tgtgcacctt gcgcggccgc
    22321 cacatgcgcg acccgatcgg gttgaccttg tcggtgccga tcatggccac cgggatgacg
    22381 ggcacgcccg cctccagcgc catccgggcg acaccggtct tgcccttgta gaggcgtccg
    22441 tcgggcgagc gggtgccctc cgggtagatc cccagcagcc ggccctcgcg cagcacccgc
    22501 accgcggtgt ccatggcgtc gcgggcggcc gacccgccgg agcggtcgat cgggatctgg
    22561 cccacgccgg tgaagaacgc cttctgcatg cggccgacca gccccggctt ggtgaagtac
    22621 tccgacttcg ccgggaacgt gatccgccgc ggcaccacca ggggcaggac gaacgagtcg
    22681 acgaccgcga ggtggttgct cgcgaggatg gccccgccgc gggccgggat gtgctcgagc
    22741 ccctcgatcg tggggcggca gaacagccgc agcagcggac cgaggaacac gaacttggac
    22801 caccagtaca gcacctgggc gtgccccctt caccgcgacg ggcgtcagcc tacggacggg
    22861 cggggcgcgg cgacaacggc ggtggcccgc atcggttccc gcaccgctgc gagcgtgtca
    22921 ggatggaggc gggccgtcgc acggcggtcc gcgcggtggc gaggagatca cgtgggcggc
    22981 gatccggacg agcgtccgca ccccgacggc tgggtcgacg acttcgacgc catcgtcgcg
    23041 ggctggcggc gcgagggcgc ggtccccgag tggcccgacg aggagccgcc cgccgccgtg
    23101 cgggagccgg ggtcgcccga cggaccgtcg tcggacctgc cgccgcccac cgcccccgag
    23161 ccgccgccga tcgtcgtccg gccggggccg cgcacggccc ccgaggacga ccacttcgtg
    23221 cccccggagc cgccgccgat cccccgcatc gggccgcccg cggccgtcgg cctggtgctg
    23281 ctggtgctcg ggatcgtcct ggtcaccgcg cccggctggg tcggggtgcc cgacacctac
    23341 ggcctgccgc tcgggctgct caccctcgcg gccggcctcg gctggctggt gctgcgcctg
    23401 tggccctccc cgcccggccc ggggcaggac gacgacgggg cgatcctgta gccgtctcag
    23461 acggcggcgg ccgctgccag gtagcgggtc tcggcccgct gcagcagcag gacgacgacc
    23521 gcgcccacca cgctcagcac gatcccgacg agcacggccg tgttccaccc ggccacgagg
    23581 ctcgcggggg tgccgtcggg gtgcacggcc agcgccgtca cgaccgtgac gccgaaggcc
    23641 gcgccgatgt agcggctgga gttgttgagg ccgctgcccg cgcccgcgct ggcggccggg
    23701 acgctcgcca cggcctcacg ggccagcgtc gcgttgacca ccccgctgcc gacgcccgcc
    23761 acgaccagcc ccacgagcac ctgcgccagc ggggcgccgg tgtcgagcag cgccagcggc
    23821 agcaggccca gcgcgatcgt cagcaggccg gcggcgaggc gggccgcgcc ggggacccgc
    23881 agcgggatcc ggcgggcgag cagcgcgaac acgacgctga accccgacca gccgatgccg
    23941 atcaccgacg cctgcaccga cgtgtaggcc agaccgctct ccagcaccac ggccacgaac
    24001 gacatcagcg cgatgatcgc ggcgccggtg acgaacgcgg cgaacgtggc ggagaccagc
    24061 gcgggccggc ggaacagggc gagctccagc attggctccc gcgcccgccg ctggtgcacc
    24121 aggaacaccg cgaggacgac caccgcaccg gcgacgaggc cgagcgcgag cgggccggtc
    24181 cagccgcggc ggccctcggt gagcccggcg agcagggcgc cggtgccgac ggccagcagc
    24241 agcgccccgg tgacgtcgac ccgccggccg cgcccggagc gcgactcggt gagcaggcgc
    24301 tgcccggcga cggccagcag caccgacacc accgcgacga cgacgaacgc gaagcgccag
    24361 tccgccaccg cggccagcac cgcgccgagc ggcggcccga cggcggggcc cgcacccatg
    24421 cacgcgcccc agattcccgt ggcgcgggcg cggtcggggc cggggaacgt gtggctgatc
    24481 agcgccagcc cgcaggcgat caccgcggcg gaaccgatcc cctccagcac ccggccgacg
    24541 acgaacgtcc aggcgtcggg ggcgagggcg caggcggccg agccggccgc gagcagtgct
    24601 gccccggcga cgaacacgcg ccgccgcccg acctcgtcgc cgatggcgcc ggaggtgagc
    24661 agcgcgacgg ccagcccgag gctcatcgag ctcagcaccc aggaggtgcc gaccggaccg
    24721 gcgccgaggt cgcgcgcgac cgtcgggatg atcgagaacg gtgcggtgaa cgccgtcatc
    24781 gagagcaggg tgccgcctgc ggtgatggcg agcgtgccgc cggggcgcag gccggcgggc
    24841 ggcccgggcg gggtgccggt cgtggtgctg accgtgcggt ccatgcgcgt ctcccccggg
    24901 gttcgtggtg gcccggaccg tagcacgcgc ggttcggtca ccgaaccgat gtgcgatgat
    24961 gggcacatgg tgctgccacg ggactaccag ggtcagcggt gctcgatcgc gcggacgctg
    25021 gaggtcgtcg gcgagcgctg gtcgctgctt gtcgtccgcg acgcgttctt cggggtgcgc
    25081 cgcttcagcg acttcgcccg ccacctcggc atcccgcgcg ccgtgctcac cgagcgcctc
    25141 gaccgcctgg tggaggaggg cgtgctggag cgcgtcccgg ggccggggcg gcgctcggag
    25201 tacgcgctca cgcccaaggg cgtc
//
