LOCUS       NZ_CP053564            11467 bp    DNA     circular CON 29-MAR-2024
DEFINITION  Pseudonocardia broussonetiae strain Gen 01 chromosome, complete
            genome.
ACCESSION   NZ_CP053564
VERSION     NZ_CP053564.1
KEYWORDS    RefSeq.
SOURCE      Pseudonocardia broussonetiae
  ORGANISM  Pseudonocardia broussonetiae
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Pseudonocardia.
REFERENCE   1  (bases 1 to 7177725)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-MAY-2020) College of Life Science and Technology,
            Central South University of Forestry and Technology, No. 498,
            Shaoshan South Road, Changsha, Hunan 410004, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013155125.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 06:16:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,087
            CDSs (total)                      :: 7,032
            Genes (coding)                    :: 6,962
            CDSs (with protein)               :: 6,962
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 19 of 70
            Pseudo Genes (incomplete)         :: 48 of 70
            Pseudo Genes (internal stop)      :: 6 of 70
            Pseudo Genes (multiple problems)  :: 3 of 70
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:38:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 130048
            Orig. end                         :: 141515
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP053564.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Mo.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..11467
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11467
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11467
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6467](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..6467)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(1016..2143)
                     /locus_tag="HOP40_RS00660"
                     /old_locus_tag="HOP40_00660"
     CDS             complement(1016..2143)
                     /GO_function="GO:0008195 - phosphatidate phosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021466.4"
                     /locus_tag="HOP40_RS00660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_00660"
                     /product="phosphatase domain-containing protein"
                     /protein_id="WP_172153903.1"
                     /transl_table=11
                     /translation="MTARSWRRQLTYALLRLEDVVETGIAAGARLGGHRYPLIIPFIGH
                     GTTERARVGARLVLGRRAAVEPSAPAVRIGDAPSSPRSRRATLRVSLARFLTVEVPRAS
                     VTIHAPGGDVVVQTNRDGYIDHELELSGVAPGWLELRLSGPDGAHATARVLLVDPAVDV
                     GVISDVDDTILNTGLTRGLDFLKATLLTDVEERTPLPGAAALYRALVTKPGKPERPVFY
                     VSTSPWNLHEMLLQFVSMRGFPLGPLLLTDWGPSHTGLFRIGAQAHKPGLVRRLLDEHP
                     QLRLVLIGDSGQEDPEIYGDIAREHPDRVAAVYIRRTTGIDLGRNDEIDALAAEITALG
                     VPMRAVDDSVQIAEHASEHGLMDADAVAAVRAELS"
     gene            complement(2140..2898)
                     /locus_tag="HOP40_RS00665"
                     /old_locus_tag="HOP40_00665"
     CDS             complement(2140..2898)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014625.4"
                     /locus_tag="HOP40_RS00665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_00665"
                     /product="PIG-L family deacetylase"
                     /protein_id="WP_172153904.1"
                     /sec_met_domain="PIG-L (E-value: 2.6e-17, bitscore: 62.4,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVAVSPHLDDAVFSAGATLAALAGAGWEVVVVTCFTASVPDPP
                     PFALSTQLDKGLDASVDYLALRRAEDAAACAVLGATPVHLPLPEAPHRGYVSAPDLFAG
                     VHDDDGVRGPLADALNAHLAGVDLVLAPQGIGDHADHRVVVDVVARLAPGAAWWRDAPY
                     VLRRPDARPWSPPGERRAVDVTRHLDLKIAAARCYTTQLGFQFGGPEQVGPVLRELAAA
                     EAGPGSGGCAEVFTVPRCSAAVPGAVALLP"
     gene            complement(2909..4165)
                     /locus_tag="HOP40_RS00670"
                     /old_locus_tag="HOP40_00670"
     CDS             complement(2909..4165)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018334673.1"
                     /locus_tag="HOP40_RS00670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_00670"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_172153905.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.2e-35,
                     bitscore: 121.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVCFVSRRYWPAVSGMSAYAENLLRHLVRVGHEVTMVSQYRGDE
                     AGRAVYGGGPPPADRVPDGVQVVALEALGEQAVGRGERADFEGDVDAMTRTVLDLHEKE
                     PFDVLHAQYAYPNGLAVLRAAREAGLPAVVSVQGGDGHWVGTCCATHRDLVRAVFAHAP
                     ALLIGSPSFAAEVAQRHGIDVGRFTLVPGATDAERFTPVDGESVAPVGDPAVLLYHGRV
                     DARKGVLDLLQAVRLLRDDDVPVRLLVSGIGPDTDLVARTVDELGLRADVELLGAVPYE
                     RAHEVYRRGEVFVSPTYAEGFSNTILEAMASGLPVVSTDVVGVRDCVRPDDNGVLVPPA
                     DPPALAAGIRRVLDDDALRRRIVAQAHSDVHRLWSWPVVAGRITDVYDAVLADRAEIPE
                     IPDPPVDPDCRFRAAPHLL"
     gene            complement(4162..5004)
                     /locus_tag="HOP40_RS00675"
                     /old_locus_tag="HOP40_00675"
     CDS             complement(4162..5004)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018334674.1"
                     /locus_tag="HOP40_RS00675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_00675"
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_172153906.1"
                     /transl_table=11
                     /translation="MTLRYAYNTNGLTSHRLDDALTLLADSGYDGVALTLDVHHHDPFA
                     PALPARTRALRRQLETLGLGSVVETGARFLLDPRRKHRPTLVTEDPHARAVRVAFLRTC
                     VDVAAELGSEAVSFWAGVPAPEVDRAHAWEWLVEGVGEVVEHARNAGVTCAFEPEPGML
                     VDDCDDWARLHEAVPDLTLALDTGHCIVSGSYEPADAVRTFAGHLGACAVEDMPRGRHE
                     HRAPGEGDMDLPAVLGALADVGYRRLVSLELSRDSHRADVLVPAALAALREAESRVAA"
     gene            complement(5001..6467)
                     /locus_tag="HOP40_RS00680"
                     /old_locus_tag="HOP40_00680"
     CDS             complement(5001..6467)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014661.4"
                     /locus_tag="HOP40_RS00680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_00680"
                     /product="YcaO-like family protein"
                     /protein_id="WP_172153907.1"
                     /sec_met_domain="YcaO (E-value: 4.4e-53, bitscore: 179.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPARTGTADLLRAALGDADAGDFPISGADRVGVPVVAADVTGP
                     PRFGSFGYGHTVEQARTGAYGELVEAALLHHHLRALTPRRASYAELRRELGERGVVDPR
                     ELVLPAGTVVDDDRPRTWLPATRWRTGEAVRLPAEFCASWAPDVADQDPAERLITVITN
                     GSGAGDTAARAVAHGLLELLQRDGNGTAFRALDEGTVLDLDGVTDPVTHRVLGQLRGAG
                     ITVLAKLASTQFGLADVHVVGVDADPDAEPLAVTACGEACHPDREVALRKALLEYAAAR
                     SRKVFAHGPLDRVRPLAPPAYWERELASPVPDQEPRALAAMRDWSRRSAAELQDLLAPT
                     VLSVHRTVPFTDLPTVPPGSLDDPAALLADLLERLADLDVLVVLARGGGAVSAKVVVPG
                     LEVETMSYGRIGARGVEKLRARSNRSGRDLAGLGSPPHPGAAPVVLTAQGRERLGDDAW
                     LDLDAVAAAVGPLYPLYREPTRHALARSTA"
     gene            complement(6464..7288)
                     /locus_tag="HOP40_RS00685"
                     /old_locus_tag="HOP40_00685"
     CDS             complement(6464..7288)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018334676.1"
                     /locus_tag="HOP40_RS00685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_00685"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_172153908.1"
                     /transl_table=11
                     /translation="MPLRPYSCDNCGHWQRWFAEPPSCPVCTDVRNALPEDGWAWTTPD
                     DLAGRAARWAEVAPGVTGFWCEPQIGLGTTGWVLETDAGLVGWEGAGFYPPDALAELRR
                     RGGLVALGASHVHGYGALWQLQDELAPPVLAIDVRDLAWTKAFVVTWPTDARHELAPGL
                     VMHRSGGHFPGHAVLHDERRGILFVGDLLKVDLDGDRPVGLSCHKAYHAQIPLSHDEIR
                     EARALVERLDFEAVATPFEFAAPVTQKQVLALFDHHLGRQPLAGPVPLEELT"
     gene            complement(7290..8039)
                     /locus_tag="HOP40_RS00690"
                     /old_locus_tag="HOP40_00690"
     CDS             complement(7290..8039)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014893.4"
                     /locus_tag="HOP40_RS00690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_00690"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_205347040.1"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 1.6e-22,
                     bitscore: 78.5, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAAVAGSGLPLLCEKPLAPDVAGAQALVDAAPALAGTAFDQRFH
                     PAHRRIADIVAAGELGTVTAVRIVYGCWLPPEWSPDGTPQHNWRVDPGGGAVIDLAPHG
                     VDLVGTLLGGDDLVALSVLTRTRVHDYPVDDGGVLAGHTAGGVLYSAHVSFATPDALPR
                     RRLEVVGTRAQLVAVDTLGQTPGGTLTRVDATTGTATEVPFDTATSPFTAQLAAFSAAV
                     AGAADWPYPLHRDLALHTLLLTALERT"
     gene            complement(8349..9479)
                     /locus_tag="HOP40_RS00695"
                     /old_locus_tag="HOP40_00695"
     CDS             complement(8349..9479)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="HOP40_RS00695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_00695"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_205347041.1"
                     /transl_table=11
                     /translation="MTAPAWVAADGTPLRADTPATLTDGERRWPVVSGIAWLRAGRDDV
                     RERAVAALDDGDPDGAAVALLADADDWWDEPPPPPERLRAALHARTLRDAVTLLGLGRV
                     GVYFLHRWSDPSWLAALALTAAHPPAGRPVVDLACGAGHLLRHLASHGHRDLVGVDVVF
                     AKLWLAHRFVLPPGAASLVCADLTAPWPLPAPGRPRHVACHDALYFLPDKERVVERARA
                     AAGEGGAVLLGHCHNATHPAGRSGLPLDAPGWTALLPGSATYAEEELTAAAVEDRVALP
                     ATPAELMGTEAIGLADDDAAAPPDRTLLRPAPGAALRPNPLYGDPGGPRGRIWPHVRWA
                     EEYGPRAERYLPERWTPLPVADAVRRRLLLDLPDRW"
     gene            complement(9476..10372)
                     /locus_tag="HOP40_RS00700"
                     /old_locus_tag="HOP40_00700"
     CDS             complement(9476..10372)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018334679.1"
                     /locus_tag="HOP40_RS00700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HOP40_00700"
                     /product="HD domain-containing protein"
                     /protein_id="WP_172153909.1"
                     /transl_table=11
                     /translation="MTTVPTARLAAVVPLFREVTDLKRVRVAHAEGSVANRSFARAWAA
                     VLGGADEGAVAAAECAAALAGARLAGIDADVLAATGVADPDAVLRRAIDEVAGPLHPAT
                     VARVRVAPPVAVEPVAPPAFVDALRRQPRAGATAPGRPRLVVEPPEDHAEHCWAVAVLG
                     ALLADDLDADPGAVFLLGLAHHLHNAALPDAGFAGETLLGAELDPLLERLTERELAALP
                     DPLAGRVRDLLALRADADTPVGRAFHAADVLDRVLQVHHHARAAAFTPAQALDDLDLVH
                     AGPVTGYHDAVLAAAGL"
     misc_feature    complement(10565..10580)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.38"
                     /tool="antismash"
     misc_feature    complement(11341..11350)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 gcggcggccg gtgcccgggc tcgtcgtcca ccgcgacgtg ctcgggcccg gcgagaccgt
       61 ctgccgtggc ggtgtcctca tgaccgacgc ggtccgcacc gccttcgacc tgatccgctg
      121 ggcgcccgac ctcgtcgaga aggtcaccgc gttcgacgcg ctggcgttcc actgcggggt
      181 gacggtcgag gcggtgcggg cgctggcccg gcttcacctc ggggcgcacc acacgcgcgg
      241 gctcgaccgg gtgctggacc tgacggacgg ccgggcggag tcgccgatgg agtcgcggat
      301 ccgggtggcg gtggtgctcg acggcctgcc ggcgcccgtg gtccagcacg tggtcgaggt
      361 cgacggccgc cgctaccggc tcgacctcgc ctacccggac ctgatgctcg ccatcgagta
      421 cgacggacgc gagcaccgcg gccagcagcg ggcccacgcc gacctgcgcc gcgaggccga
      481 cctggcccgg cagggctggc ggatcctccg cttcgacgcc gtcacggtcc tgcagcaccc
      541 ggggttcgtc gtggcggagg tgcgggccga gctcgcccgc cgcgcggccc gcaccgtctc
      601 cccttgatca ccgggaccgc accaccacgg tcgccgcggg gaccgtggtg tcaccttccc
      661 gacgatcacc gagccggatc acgcaagacc gcaccaccac ggccctcgtg gcgaccctga
      721 cggcgcactt ccgacgatca agggcaggtg gcgcgccccg ccgcggaggc ggcgcaccat
      781 ccgcccttga tcaccgagac cgcaccacca cggccgccac gaggaccgtg gcgtcacctt
      841 cccgacgatc accgagccgg atcacgcaag accgcaccac cacggccctc gtggcgaccc
      901 tgacggcgca ctcccgacga tcaagggcag taggcgagcc ggccgaggcc cgcccgcacc
      961 atctcccctt gatcaccgag accccaccac cacagccgcg tgccggcggc tcggctcagc
     1021 tcaactccgc ccgcaccgcc gccaccgcat cggcgtccat caacccgtgc tccgacgcgt
     1081 gctcggcgat ctgcacgctg tcgtccaccg cccgcatcgg cacgcccagg gcggtgatct
     1141 cggccgccag tgcgtcgatc tcgtcgttgc ggcccaggtc gatgccggtg gtgcggcgga
     1201 tgtagacggc ggcgacgcgg tcggggtgct cgcgggcgat gtcgccgtag atctcggggt
     1261 cctcctggcc gctgtcgccg atcagcacca gccggagctg ggggtgctcg tcgagcaggc
     1321 ggcggaccag gccgggcttg tgggcctgcg cgccgatccg gaacaggccc gtgtgcgagg
     1381 ggccccagtc ggtcagcagc agcgggccga gcgggaagcc gcgcatcgac acgaactgca
     1441 gcagcatctc gtgcaggttc cacgggctcg tcgacacgta gaacacgggc cgctcgggct
     1501 tgcccggctt cgtcaccagc gcgcggtaca gggcggcggc accggggagc ggggtgcgct
     1561 cctcgacgtc ggtgagcagg gtggccttga ggaagtcgag gccgcgggtg aggccggtgt
     1621 tgaggatcgt gtcgtcgacg tcgctgatga cgcccacgtc gacggccggg tcgaccagca
     1681 gcacgcgcgc cgtggcgtgc gcgccgtcgg ggccgctcag ccggagctcc agccacccgg
     1741 gcgcgacgcc ggagagctcc agctcgtggt cgatgtagcc gtcgcggttg gtctgcacga
     1801 cgacgtcgcc gccgggcgcg tggatcgtca ccgacgcccg cggcacctcg acggtgagga
     1861 accgcgcgag gctgacccgc agggtcgccc ggcgcgaccg cggcgaggac ggggcgtcgc
     1921 cgatgcgcac cgcgggcgcc gacggctcga cggccgcgcg ccgccccagc accagccgcg
     1981 caccgacccg cgcgcgctcg gtggtgccgt gcccgatgaa cgggatgatg agcgggtacc
     2041 ggtgcccccc gaggcgggcg cccgcggcga tcccggtctc cacgacgtcc tccaaccgga
     2101 ggagggcgta cgtgagctgt ctgcgccaac tgcgtgccgt cacgggagta gggctaccgc
     2161 accgggtacc gcggcgctac accggggcac cgtgaacacc tccgcgcacc cgccggatcc
     2221 ggggcccgcc tcggccgccg ccagctcgcg cagcaccggc cccacctgct ccggaccgcc
     2281 gaactggaac cccagctggg tcgtgtagca gcgggcggcg gcgatcttga ggtccaggtg
     2341 ccgggtgacg tcgacggcgc gccgctcccc cggcggcgac cacggccgcg cgtccgggcg
     2401 ccgcagcacg tacggcgcgt cgcgccacca cgccgccccg ggcgcgagcc gggccaccac
     2461 gtcgacgacg acccggtggt cggcgtggtc gccgatcccc tgcggcgcca gcaccaggtc
     2521 gacgccggcg aggtgcgcgt tgagggcgtc ggcgagcggg ccgcgcaccc cgtcgtcgtc
     2581 gtggacgccc gcgaacaggt ccggggcact cacgtagccg cggtgcggcg cctcgggcag
     2641 cggcaggtgc accggcgtcg cgccgagcac cgcgcaggcg gcggcgtcct cggcgcggcg
     2701 cagggccagg tagtcgacgg acgcgtcgag gcccttgtcc agctgcgtcg acagcgcgaa
     2761 cggcggcggg tccggcacgc tcgcggtgaa gcaggtgacg accacgacct cccatcccgc
     2821 cccggcgagc gcggccaggg tcgcgcccgc ggagaacacg gcgtcgtcca ggtgcgggga
     2881 gaccgccacg gccctcacag cgccgccctc acagcaggtg cggcgccgcg cggaaccggc
     2941 agtccgggtc gacgggcggg tcggggatct ccgggatctc cgcgcggtcg gcgagcacgg
     3001 cgtcgtagac gtcggtgatc cgccccgcga ccaccggcca cgaccagagc cggtgcacgt
     3061 cggagtgcgc ctgcgcgacg atccgccggc gcagcgcgtc gtcgtcgagc acgcggcgga
     3121 tgccggcggc cagcgcgggc gggtcggcgg gcggcacgag gacgccgttg tcgtccggcc
     3181 ggacgcagtc ccgcacgccc accacgtcgg tcgacaccac cggcagcccc gacgccatcg
     3241 cctccaggat cgtgttcgag aacccctcgg cgtaggtcgg gctgacgaac acctcaccgc
     3301 gccggtagac ctcgtgcgcc cgctcgtagg gcacggcgcc cagcagttcg acgtcggcgc
     3361 gcagaccgag ctcgtcgacg gtgcgggcga cgaggtcggt gtcgggcccg atcccggaga
     3421 cgagcagccg cacgggcacg tcgtcgtcgc gcagcaggcg gacggcctgc agcaggtcga
     3481 gcacgccctt ccgggcgtcg acgcgaccgt ggtagagcag cacggcgggg tcgccgaccg
     3541 gcgcgaccga ctccccgtcg acgggtgtga accgctccgc gtcggtggcg ccgggcacga
     3601 gcgtgaaccg cccgacgtcg atgccgtggc gctgcgcgac ctccgcagcg aaggacggcg
     3661 agccgatcag cagcgcgggc gcgtgcgcga acaccgcgcg gaccaggtcg cggtgcgtgg
     3721 cgcagcaggt gccgacccag tgcccgtcgc caccctgcac cgacaccacc gcgggcagcc
     3781 cggcctcccg cgcggcgcgc agcacggcga ggccgttggg gtaggcgtac tgggcgtgca
     3841 ggacgtcgaa gggctccttc tcgtgcaggt cgaggacggt gcgggtcatc gcgtcgacgt
     3901 cgccctcgaa gtcggcgcgc tccccgcgcc cgacggcctg ctcgcccagc gcctccagcg
     3961 cgacgacctg cacgccgtcg ggcacccggt cggcgggcgg cgggccgccg ccgtagacgg
     4021 cgcgcccggc ctcgtcgccg cggtactgcg acaccatcgt cacctcgtgc ccgacgcgca
     4081 cgaggtggcg cagcaggttc tccgcgtagg cgctcatgcc cgagacggcg ggccagtagc
     4141 ggcgggagac gaagcagacc ctcatgccgc cacccggctc tccgcctcgc gcagcgcggc
     4201 gagcgcggcg ggcacgagga cgtcggcgcg gtgggagtcg cgcgagagct cgagcgacac
     4261 cagccgccgg tagccgacgt cggcgagcgc gcccagcacg gcgggcaggt ccatgtcgcc
     4321 ctcgccgggg gcgcggtgct cgtggcgccc gcggggcatg tcctcgacgg cgcacgcccc
     4381 gaggtgcccg gcgaaggtgc gcacggcgtc ggcgggctcg taggagccgg agacgatgca
     4441 gtggccggtg tcgagcgcga gcgtgaggtc cgggacggcc tcgtgcaggc gcgcccagtc
     4501 gtcgcagtcg tcgacgagca tccccggctc gggctcgaac gcgcaggtca cccccgcgtt
     4561 gcgggcgtgc tccacgacct cgccgacgcc ctccaccagc cactcccacg cgtgcgcgcg
     4621 atccacctcc ggcgccggga cgcccgccca gaacgacacg gcctcgctgc ccagctcggc
     4681 ggcgacgtcc acgcaggtgc gcaggaaggc gacgcggacg gcgcgcgcgt gcgggtcctc
     4741 cgtgacgagc gtgggccggt gcttgcggcg cgggtcgagc aggaaccgcg cgccggtctc
     4801 cacgacgctg ccgagcccga gggtctccag ctgccggcgc agcgcgcgcg tgcgggcggg
     4861 cagcgcgggg gcgaacgggt cgtggtggtg cacgtcgagg gtgagcgcga cgccgtcgta
     4921 gccggagtcg gcgagcagcg tgagcgcgtc gtcgaggcgg tggctggtca ggccgttggt
     4981 gttgtaggcg taccggaggg tcatgcggtg ctcctcgcca gtgcgtgccg ggtgggttcg
     5041 cggtaaaggg ggtagagcgg gccgacggcc gcggcgacgg cgtcgaggtc gagccacgcg
     5101 tcgtcgccga ggcgctcgcg tccctgcgcg gtgagcacga cgggggccgc gccggggtgc
     5161 gggggcgacc cgaggcccgc gagatcccgc ccggaccggt tgcttcgggc ccgcagcttc
     5221 tccaccccgc gcgccccgat ccggccgtag gacatggtct cgacctccag ccccgggacg
     5281 acgaccttcg cgctcaccgc gcccccgccg cgggcgagca ccacgaggac gtccaggtcg
     5341 gcgaggcgct ccaggaggtc ggcgagcagc gccgccgggt cgtcgaggga gcccgggggc
     5401 accgtcggga ggtcggtgaa cgggacggtc cggtggacgc tgagcaccgt cggcgcgagc
     5461 aggtcctgca gctcggcggc gctgcggcgc gaccagtcgc gcatcgccgc cagcgcccgc
     5521 ggctcctggt ccggcaccgg ggacgccagc tcgcgctccc agtacgcggg cggggcgagc
     5581 gggcggacgc ggtccagcgg gccgtgcgcg aacaccttgc gcgagcgcgc ggccgcgtac
     5641 tccagcaggg ccttgcgcag cgcgacctcc cggtccgggt ggcacgcctc cccgcacgcg
     5701 gtgacggcca gcggctcggc gtccgggtcg gcgtcgacgc cgacgacgtg cacgtcggcc
     5761 agcccgaact gcgtcgacgc gagcttggcc agcaccgtga tcccggcgcc gcgcagctgc
     5821 ccgagcacgc ggtgcgtgac ggggtcggtg acgccgtcca ggtcgaggac ggtgccctcg
     5881 tcgagcgcgc ggaacgcggt gccgttgccg tcgcgctgca gcagctccag gaggccgtgg
     5941 gcgacggcgc gcgccgcggt gtcgccggcg cccgagccgt tggtgatcac cgtgatcagc
     6001 cgctcggccg ggtcctggtc ggcgacgtcg ggcgcccagg acgcgcagaa ctccgccggc
     6061 agccggacgg cctccccggt gcgccagcgc gtcgcgggga gccaggtgcg gggccggtcg
     6121 tcgtcgacga cggtgccggc gggcagcacc agctcccggg ggtcgacgac gccgcgctcc
     6181 ccgagctcgc ggcgcagctc cgcgtaggag gcccggcgcg gggtgagcgc gcgcaggtgg
     6241 tggtgcagca gcgcggcctc gaccagctcg ccgtaggcgc cggtgcgggc ctgctcgacg
     6301 gtgtggccgt agccgaagga gccgaaccgc gggggcccgg tgacgtccgc ggccaccacc
     6361 ggcaccccga cgcggtcggc gccggagatc gggaagtcgc cggcgtcggc gtcgcccagt
     6421 gcggcgcgca ggaggtcggc ggtgcccgtc ctggcgggtg cgctcacgtc agctcctcca
     6481 gcggcaccgg ccccgccagc ggctgccgcc cgaggtggtg gtcgaacagg gcgagcacct
     6541 gcttctgcgt caccggggcg gcgaactcga acggcgtggc gacggcctcg aagtccaggc
     6601 gctccaccag cgcgcgggcc tcgcggatct cgtcgtggga gagcgggatc tgggcgtggt
     6661 aggccttgtg gcagctcagc ccgaccggcc ggtcgccgtc gaggtcgacc ttgagcaggt
     6721 cgccgacgaa caggatcccg cggcgctcgt cgtgcaggac ggcgtggccc gggaagtgcc
     6781 cgccggaccg gtgcatcacc aggcccggcg ccagctcgtg gcgggcgtcg gtgggccagg
     6841 tgacgacgaa cgccttggtc caggcgaggt cgcggacgtc gatcgcgagg acgggcggcg
     6901 ccagctcgtc ctggagctgc cacagcgcgc cgtagccgtg gacgtggctc gcccccagcg
     6961 cgaccagccc gccccggcgg cgcagctcgg ccagcgcgtc gggcgggtag aagccggcgc
     7021 cctcccagcc gacgagcccg gcgtcggtct ccaggaccca gccggtggtg ccgagcccga
     7081 tctgcggctc gcaccagaac ccggtgacgc ccggcgcgac ctcggcccag cgcgcggcgc
     7141 ggccggcgag gtcgtcgggc gtcgtccagg cccagccgtc ctcgggcagc gcgttgcgga
     7201 cgtcggtgca cacggggcag gacggtggtt cggcgaacca gcgctgccag tgcccgcagt
     7261 tgtcgcacga gtaggggcgc aggggcatgt caggtcctct cgagcgcggt gagcagcagg
     7321 gtgtgcaggg cgaggtcgcg gtgcagcggg tagggccagt ccgcggcgcc cgcgacggcg
     7381 gcggagaacg cggcgagctg cgcggtgaag gggctggtgg cggtgtcgaa cgggacctcg
     7441 gtggccgtgc ccgtggtggc gtcgacgcgc gtcagcgtgc cgccgggcgt ctggccgagg
     7501 gtgtcgacgg cgacgagctg cgcgcgcgtc ccgacgacct ccaggcggcg ccgcgggagg
     7561 gcgtcgggcg tggcgaagga gacgtgcgcg gagtacagga cgccgcccgc ggtgtgcccg
     7621 gcgaggacgc cgccgtcgtc gacggggtag tcgtggaccc gcgtgcgggt gaggaccgag
     7681 agcgcgacga ggtcgtcgcc gccgagcagg gtgccgacga ggtcgacgcc gtgcggggcg
     7741 aggtcgatca ccgcgccgcc gcccgggtcg acgcgccagt tgtgctgcgg agtcccgtcg
     7801 ggcgaccact ccggcggcag ccagcagccg tagacgatcc gcaccgcggt gaccgtgccc
     7861 agctcgccgg ccgccacgat gtccgcgatc cgccggtggg cggggtggaa gcgctggtcg
     7921 aaggcggtgc cggcgagggc gggggcggcg tcgacgagtg cctgcgcgcc cgcgacgtcc
     7981 ggggcgaggg gcttctcgca caggagcggg aggccggagc cggcgacggc ggccaccacg
     8041 gcggggtggg tgtgggtggg gggtggcgag gtagagggcg tggaggtcgg ggaggtgcag
     8101 gaggccgtcg agggcgtccg gagttgcagg aaagccacgt tcccgcaacg gggtggcggg
     8161 aacgtggctt tcctgacccc cggcgccggc cccgcggtac gccgccaccg ccgcccgcgc
     8221 cgccgcggga tcccggtcgt gcacccccac cacccgcgcc cccgccacgg cccgcatccc
     8281 gggcaggacg tggtcgcgcg ccacccagcc gcagccgacg acgccccagt tcacgactcc
     8341 gtgcaccctc accaccggtc cggcaggtcg agcagcagcc gccggcgcac ggcgtcggcg
     8401 acgggcaggg gcgtccaccg ctccgggagg tagcgctcgg cccgcggccc gtactcctcc
     8461 gcccaccgca cgtgcggcca gatccggccg cgcgggccgc cggggtcgcc gtagaggggg
     8521 ttggggcgca gggcggcacc cggtgcgggc cgcagcagcg tgcggtcggg cggggccgcg
     8581 gcgtcgtcgt cggccagccc gatcgcctcg gtacccatca gctcggcggg cgtcgccggg
     8641 agcgcgacgc ggtcctcgac ggccgccgcc gtcagctcct cctccgcgta ggtcgccgag
     8701 ccgggcagca gcgccgtcca gccgggcgcg tcgagcggca ggcccgagcg cccggcgggg
     8761 tgcgtggcgt tgtggcagtg cccgagcagc accgccccgc cctcgcccgc cgcggcccgc
     8821 gcccgctcga cgacccgctc cttgtcgggc aggaagtaca gcgcgtcgtg gcacgcgacg
     8881 tggcgcggac gcccgggcgc gggcagcggc cagggcgcgg tgaggtccgc gcacaccagc
     8941 gacgccgccc cgggcggcag cacgaaccgg tgcgccagcc acagcttggc gaacaccacg
     9001 tcgacgccga ccaggtcgcg gtgcccgtgc gaggcgaggt ggcgcagcag gtgaccggcc
     9061 ccgcaggcga ggtcgacgac cggacgcccg gcgggcgggt gcgcggcggt cagcgcgagg
     9121 gcggccagcc agctggggtc cgaccagcgg tgcaggaagt agacgccgac gcggccgagg
     9181 ccgagcagcg tcacggcgtc gcgcagcgtc cgcgcgtgca gcgccgcccg cagccgttcc
     9241 ggcggcggcg ggggctcgtc ccaccagtcg tcggcgtcgg cgagcagggc cacggcggcg
     9301 ccgtcggggt caccgtcgtc gagcgcggcg acggcccgct cccgcacgtc gtcgcgcccg
     9361 gcccgcagcc acgcgatccc cgagacgacc ggccagcgcc gctccccgtc ggtgagcgtg
     9421 gcgggggtgt cggcgcgcag cggggtgccg tcggccgcga cccaggcggg agcggtcaca
     9481 gcccggccgc cgcgaggacc gcgtcgtggt agccggtgac gggtccggcg tgcacgaggt
     9541 cgaggtcgtc gagcgcctgc gccggggtga acgcggccgc gcgggcgtgg tggtggacct
     9601 gcagcacgcg gtcgaggacg tccgcggcgt ggaacgcccg cccgaccggg gtgtccgcgt
     9661 cggcgcgaag cgcgagcagg tcccgcacgc gcccggccag cgggtcgggc agcgcggcga
     9721 gctcgcgctc ggtgagccgc tccagcagcg ggtcgagctc cgcgcccagc agcgtctccc
     9781 ccgcgaaccc ggcgtcgggc agggccgcgt tgtgcaggtg gtgggcgagc ccgagcagga
     9841 acaccgcgcc cgggtcggcg tcgaggtcgt cggccagcag cgccccgagg acggcgacgg
     9901 cccagcagtg ctcggcgtgg tcctccggcg gctcgacgac gaggcgcggg cgccccggcg
     9961 ccgtcgcccc ggcccggggc tgccggcgca gggcgtcgac gaacgcgggc ggcgcgacgg
    10021 gctccaccgc caccggcggg gcgacccgga cccgggccac cgtcgcgggg tgcagcggcc
    10081 cggccacctc gtcgatcgcc cggcgcagca cggcgtccgg gtcggcgacc cccgtggcgg
    10141 ccagcacgtc ggcgtcgatc ccggccaggc gcgcgccggc cagcgccgcc gcgcactccg
    10201 cggcggccac cgcgccctcg tcggcgccgc ccaggaccgc ggcccacgcc cgtgcgaagg
    10261 accggttcgc gacggaaccc tccgcgtgcg cgacccgcac ccgcttgagg tcggtgacct
    10321 cccggaacag cggcaccacc gccgccagcc gcgcggtggg gaccgtcgtc accctcggtc
    10381 cagccagtcc agcagcacct gctcctgcag gtgcagcgcg tgctcgggca cgccgccgtc
    10441 ggacgtcatc ggctgcttga agaagtaccc cagctgctcc tgcgcgccgc cctcgccgcg
    10501 ccgcgcggcc tcggcgacca agcgcaccag ctccagcacc agcggcgccg cgaggatcga
    10561 gtcgcggcac aggaagtcga tcttcatctg catccgctgg cccatgaagc cgacgaggtc
    10621 gatgttgtcc caggcctcct tggcgtcgcc gcgggggcgg tagtagtcga tccgcaccac
    10681 gtggtcgtcg acgtcgtagc cgaggatgga gtcgagcacc gaccccttcg tgtccagctt
    10741 gctggccagc gacgacgggt cgtcgaggat ctggccgtcg cggttgccga ggatgttggt
    10801 cgagtaccag ccctcgacgg tgagcgcgcg cgagcggaac gcgggcgcca gcaccgtctt
    10861 gaccatcgtc tgcccggtct tgccgtcctt gcccgccacc ggcacgttct cgcgcgcggc
    10921 cagctccagc agggcgggca cgtccgggcc gaggctcggc gtgaagttga cgaacgggca
    10981 gccctcggtg atcgcggcgt aggcgtagac catgcccggc gtgatcaccg ggtcgtcgag
    11041 gtcgaggccc ttctcgaacg tgtcgaggtc gccgaggatc gccgacgtgc ggtccggcca
    11101 cgcctcggtc gaggcgaggt tgacgacgac gaccgtgtcg agcgactgct cctcgcggaa
    11161 gcgacgcagg tcgtcgcgca ggtgggcgac gcgctcgcgc agcggcccga cgggcacgac
    11221 gttcgcgccg accgcgttgc ggcagtaggc cgggtcgacc accgcgggcc acggcgagat
    11281 cgacgcgagg ggttcggcga cggcgtcgag ctgcgccggc tcgatgacgc ggtgcaccgc
    11341 ggccgccttc gccaggtcgc tgccgtcgag gtcccagccc gcgaacacca gcgactcgta
    11401 gggcgcgagc tccgtgcggt gcgccagcgg gaggccgtcg gtgccgatgg tgccgagccg
    11461 gagctgc
//
